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With the advent of bioinformatics, research into the restriction - modification (rm) of dna received a strong impulse, both to further evaluate basic research aspects and develop new tools for genetic engineering . After reaching a relative plateau over 10 years ago in the search for new prototype specificities using t... |
Since the first demonstration of specific brain sites involved in pleasure, extensive animal research has identified striatal and midbrain areas and their dopaminergic and glutamatergic projections to other brain structures as key components that regulate the reward circuit (for reviews see refs 31,32). Researchers usi... |
Male db / db and nondiabetic (db / m) mice aged 3, 7, and 15 weeks (bks.cg-m + /+ lepr / j; the jackson laboratories, bar harbor, me) were infected with an adenovirus coding for human ace2 (hace2) upstream of an enhanced green fluorescent protein (egfp) reporter gene (ad - hace2-egfp) or with the egfp virus alone (ad -... |
This clinical trial conformed to good clinical practice, the declaration of helsinki (2000), and all applicable regulatory requirements . Protocol approval was obtained from each study site's ethics committee or institutional review board . Written informed consent was obtained from subjects or from parents or guardian... |
The canadian population is aging, a trend that is expected to continue for the next several decades due to a reduced fertility rate, an increase in life expectancy, and the aging of the baby boom cohort . In 2011, an estimated 5 million canadians were 65 years of age or older, a number that is expected to double in the... |
The samscl gene was inserted into a pet15b vector with a stop codon at glu 95 introduced by site - directed mutagenesis to generate the samscl - c26 mutant . The channel was overexpressed in bl21-gold cells and purified in the detergent ldao by immobilized metal affinity and gel filtration chromatographies . Crosslinki... |
Scapholunate perilunate dissociation is the most common perilunate instability pattern seen in clinical practice [1, 2]. Perilunate dislocations may be due to ligamentous injuries (following the lesser arc) or osseoligamentous disruption combining fracture of one or more carpal bones with ligament injuries (the greater... |
Currently computed tomography pulmonary angiography (ctpa) has become a widely accepted clinical tool in the diagnosis of acute pulmonary embolism (pe) (1) with a high sensitivity (up to 94 - 96%) and specificity (up to 94 - 100%) as consequence to the recent developed ctpa techniques (2 - 4). Despite high sensitivity ... |
In fact, most of us credit our best work to that modified based on editorial and reviewer feedback . In this respect, editors and reviewers can (and do) recommend additional steps that strengthen reporting and clinical interpretations . Examples include encouraging authors to incorporate additional literature, to condu... |
Seventy five million unwanted pregnancies annually occur in the world, 50 million of which lead to termination of pregnancy and 20 million ends up with unsafe abortions . Itresults to 55000 deaths happen in the world, particularly in developing countries (95%) (1). The number of unwanted pregnancies in iran, as a devel... |
Ornithine transcarbamylase (otc; omim 300461), a mitochondrial matrix enzyme, is one of the enzymes involved in the urea cycle; this enzyme catalyzes the biosynthesis of citrulline from ornithine and carbamyl phosphate . The human otc gene is located on the short arm of the x chromosome (1), and otc deficiency (omim 31... |
Leishmaniasis is one of the neglected tropical diseases (ntds), which are a group of infection diseases in tropical and subtropical areas in 149 countries, mostly common in low - income population, that affect more than one billion people (1). Leishmaniasis is caused by protozoan parasites of the genus leishmania trans... |
One - repetition maximum (1rm) lifts are one of the major methods of evaluating strength performance among college football players and are considered by most strength and conditioning professionals to be the most valid and reliable measures of muscular strength . However, there may be occasions when a non - performanc... |
Acute lupus pneumonitis (alp) is a rare initial presentation of systemic lupus erythematosus (sle). We report a 19-year - old female presenting with fever and recurrent hemoptysis with radiological evidence of parenchymal lung involvement with mild pleural effusion . A 19-year - old previously healthy girl presented wi... |
To address this question without oversimplifying or guessing at the complexity of cells, we consider a chemical species x1 that affects the production of a second species x2, which in turn indirectly controls the production of x1 via an arbitrarily complicated reaction network with any number of components, nonlinear r... |
All participants were fully informed of risks and discomforts associated with the experiment before giving informed written consent . The study was approved by the ethics committee in copenhagen county and conducted in accordance with the guidelines of the declaration of helsinki . The diabetic patients were recruited ... |
Oral lesions in denture wearers constitute a heterogeneous group of tissue changes, both with regard to pathogenesis, clinical and histopathological appearance, and possible complications . Dentures may be the direct cause of these conditions, due to changing environmental conditions of the oral cavity and loading of t... |
Human cancers rely on multiple overlapping signal transduction pathways to activate and regulate cellular proliferation, survival and migration programs . The epithelial - to - mesenchymal transition (emt) is a critical process in embryonic development for metazoan organisms and a similar process has also been shown to... |
Recent progress in biotechnology and medical care has increased the number of surviving preterm newborns worldwide [1, 2]. Advances in perinatal medical care have increased the survival rate of infants delivered prematurely; more than 80% of very low birth weight (vlbw) infants survive in developed countries [3, 4]. Th... |
Virtually all neurodevelopmental disorders are defined by deficits in brain circuitry and function that unfold as an individual develops . Presumably, differential ontogeny of neural connectivity that is, when, how, and which specific brain circuits are affected dictates the presentation of clinical phenotypes that cha... |
Malaria is endemic in 104 countries with estimated 207 million clinical cases and 627,000 deaths, representing a major global public health problem . It mainly affects children, pregnant women, and non - immune adults who frequently die as victims of cerebral manifestations and anemia . Both of these malarial complicat... |
Chronic liver disease leads to several complications, with high morbidity and mortality rates . A worldwide health problem, chronic liver inflammation is a progressive disease with a slow stage, causing liver dysfunction, characterized by the formation of fibrosis . The chronicity of inflammation, as well as the type o... |
On june 9, 1999, the first report of e. coli in a person who had visited an open farm in north wales was made to the communicable disease control team of north wales health authority . Six days later, on june 15, two more patients with culture - positive e. coli o157 infection reported having visited the farm . The far... |
There is strong evidence from experiments in animal models and epidemiologic studies that cyclooxygenases are intimately involved in the promotion and progression stages of nmscs, and therefore, may be excellent targets for the prevention of nmscs (rundhaug and fischer, 2008). There are two major cyclooxygenase isoform... |
Herniated lumbar disc is one of the most frequent medical problems18), and for decades, lumbar discectomy has been one of the most common surgical practices performed by neurosurgeons22). Today, lumbar spinal fusion surgery has been commonly performed for patients who present with chronic back pain with neurological sy... |
The physical properties of these materials can be modulated by different factors, such as composition, light source, and the length of the curing time.13 different factors related to the composition may affect the mechanical properties of the material, such as the type and concentration of the monomer that is used4, or... |
As part of the centers for disease control and prevention investigation, vero cell culture isolates of wnv were obtained from pools of culex quinquefasciatus (say) mosquitoes collected during august 19, 2010, at multiple sites in the study areas (figure 1). Kf704145kf704159) for the envelope (e) protein coding regions ... |
There are approaches to femoral tunnel placement in arthroscopic acl reconstruction: the tibial tunnel - dependent approach (transtibial technique) and the tibial tunnel - independent approach (anteromedial [am] and outside - in techniques). Femoral tunnel placement using the transtibial technique is a common and relat... |
Vaccines are one of the most effective preventative health tools available against infectious diseases, cancer, allergy, and autoimmune diseases . Vaccination aims to generate a strong immune response to the administrated antigen and provide long - term protection against a disease . Vaccine adjuvants are compounds tha... |
Since 2000 the interest in micrornas (mirnas) and their role as gene expression regulators has grown immensely . Lee et al were the first to identify such a small regulator: the lin-4 rna in caenorhabditis elegans . It has been shown that the 21 nt lin-4 rna represses mrna and controls part of the c elegans larval deve... |
Progress in human immunodeficiency virus (hiv) treatment has resulted in up to nearly 80% of patients reaching viral suppression (ie, hiv-1 rna <200 copies / ml), with reduction of mortality and morbidity of hiv.1 the increase of virological success is reflected in an improvement in clinical and immunological outcomes ... |
Multidrug efflux pumps cause serious problems in cancer chemotherapy and in the treatment of bacterial infections . In bacteria, drug resistance is often associated with multidrug efflux pumps, which decrease cellular drug accumulation . In gram - negative bacteria, pumps belonging to the resistance division family are... |
An editorial error resulted in this article appearing in the wrong supplementary issue, here: jia et al . The full text remains available in both issues for the readers convenience . For citation purposes, please use the details of this republished version: jia et al . Mapping splicing quantitative trait loci in rna - ... |
Major neurological disorders among children include epilepsy, headache, migraine, cerebral palsy, behavior related disorders - attention deficit hyperactive disorder (adhd), breath holding spells (bhss), autism and related pervasive developmental disorders (pdds), developmental delay, and neurodegenerative diseases, et... |
Hodgkin lymphoma (hl) is a highly curable lymphoma with overall cure rates exceeding 80% and over 90% with limited stage disease . The improved survival has led to the concern about long - term effects of cancer therapy adversely affecting the quality of life of these children . Computerized tomography (ct) scan is cur... |
Migraine without aura (moa) could be considered common during the pediatric age, with a prevalence ranging from 2% to 17%.1,2 moa is not just a painful condition, it is often accompanied by comorbidities that may lead to significant disability.3 in fact, children and adolescents affected by moa could present a higher r... |
There is compelling evidence that the virus - specific cytotoxic t lymphocyte (ctl) response is an important factor in the control of human and simian immunodeficiency viruses (hiv and siv, resp .) In infected individuals . Failures in antibody - based vaccines emphasize the importance of the cd8 + t lymphocyte respons... |
Acinetobacter spp . Are glucose - nonfermentative, nonmotile, nonfastidious, catalase - positive, oxidase - negative, aerobic gram - negative coccobacilli . Acinetobacter baumannii has emerged as an important pathogen causing a variety of infections including pneumonia, bloodstream infections, skin and soft tissue infe... |
The combination therapy of daclatasvir, a hepatitis c virus (hcv) ns5a inhibitor, and asunaprevir, a second - generation ns3/4a protease inhibitor, was approved in july 2014 in japan as the first interferon (ifn)-free therapy for chronic hepatitis c (chc) caused by hcv genotype 1b . This combination therapy has been sh... |
Klotho is a single - pass transmembrane protein with a long extracellular domain and short cytoplasmic tail that appears to modulate aging [1, 2]. Despite the specific predominant expression of klotho in the kidney, parathyroid gland, and choroid plexus of the brain, the extracellular domain of klotho may be cleaved an... |
The carnitine palmitoyltransferase ii (cpt-2) enzyme is located in the inner mitochondrial membrane and is associated with -oxidation of long - chain fatty acids, . Cpt-2 converts long - chain acylcarnitine (lcac), which is transferred from long - chain acyl - coa by cpt-1, back to long - chain acyl - coa . Cpt-2 defic... |
Dengue fever (df) is an acute mosquito borne transmitted disease caused by the df virus of family flaviviridae, the most common cause of arboviral disease in the world . The dengue virus (denv) are four genetically related, but distinct serotypes designated denv-1, denv-2, denv-3 and denv-4 are circulating world - wide... |
A 75-year - old man visited a local hospital complaining of abdominal pain and melena . His computed tomography showed a 7 cm - sized abdominal aortic aneurysm and suspected an aortoenteric fistula (fig . When he arrived at the emergency room, his blood pressure was 70/40 mmhg, his heart rate was 120/min, and the body ... |
Melanoma is one of the most common types of cancer in denmark and the incidence has increased markedly during the recent decades, and by more than 50% in the present study period (from 1136 cases in 2004 to 1886 cases in 2009).1 the prognosis is highly dependent on cancer stage at diagnosis, with 5-year survival decrea... |
According to mantini et al ., the left hepatic vein (lhv) draining into the coronary sinus (cs) is an extremely rare finding classified as type ia2 of congenital abnormalities involving the coronary sinus . The anomalous vein is usually a single vessel that arises from the left hepatic lobe, passes through the diaphrag... |
Desmosomes are complex intercellular junctions comprising 3 major families of proteins: transmembrane cadherins (desmogleins and desmocollins), armadillo family proteins (plakoglobin and plakophilin), and plakins (desmoplakin). The amino - terminal extracellular domains of desmosomal cadherins form the adhesive interfa... |
The cutaneous t - cell lymphoma is characterized by skin infiltrating and/or circulating malignant cells displaying a cd4+cd7 phenotype in the majority of cases . Cd4 + t lymphocytes from a nonmalignant cloned human t - cell line have been recently reported to produce a 92-kd gelatinase (mmp 9). Apart from production o... |
In the broadest sense, synthetic biology attempts to understand and mimic biological systems in order to provide novel biologically inspired solutions for a variety of challenges, such as medicine, energy production and product manufacturing . Rnas, such as short interfering rnas (sirnas), aptamers, riboswitches and ri... |
Differences in prevalence relate to age, socioeconomic status, and geographic location [1, 2]. H. pylori infection is commonly associated with gastritis, gastric cancer, and peptic ulcer disease, as well as with a variety of extragastric manifestations [35]. The infection elicits a robust inflammatory response that in ... |
Primary treatment includes surgical excision with partial or total cystectomy along with removal of umbilicus, urachus tract with or without pelvic lymphnode dissection . Common metastatic sites include lung, liver, and bone . Here, we report a case of urachal carcinoma treated with surgical excision, which presented a... |
Laboratory mouse is one of the central model organisms in modern biology, especially since the sequencing of mouse genome . Mouse strains differ not only in the coat color but also in blood parameters, immune response, behavior and reaction to stress, and susceptibility to diseases, that is, atherosclerosis, diabetes a... |
Their delving into sports originally thought to be exclusively preserves for adults, but by commission, they were exposed to corresponding head injuries of adult sports . This is more common among teens in the western world . In our own local settings, we presented an unusual case of a shot putt used during regular sch... |
Osteoblastomas are rare bone tumors, accounting for approximately 1% of all primary bone neoplasms . These tumors typically arise in the spine and show a 3:1 male predominance.1 lesions involving the temporal bone are extremely rare, with 22 total cases reported in the english - language literature and only 8 cases rep... |
Chronic lymphocytic leukemia (cll) is a slowly progressive disorder of abnormal and malignant neoplastic proliferation of b lymphocytes . Acute myeloid leukemia (aml) is a rapidly progressive disorder of abnormal and malignant neoplastic proliferation of myeloid cells and their precursors . In the united states, a smal... |
Radical hysterectomy (rh) remains as the preferred surgical option for the management of early stage cervical cancer . Other indications include recurrence after radiation therapy, selected patients with upper vaginal carcinoma and other rare malignancies of the cervix . The goal of this surgery is to remove the tumor ... |
A significant improvement was the introduction of new molecular classification that recognized five types of breast carcinoma: luminal a, luminal b, basal - like, human epidermal growth factor receptor (her)-2/neu and unclassified . The main goal of this classification was to clarify the molecular markers of prognosis ... |
This was a prospective observational diagnostic accuracy study in patients recruited during the winter months of 2006 to 2008 in two hospitals with acute medical admission units within the university hospitals of leicester nhs trust, england . Patients were adults aged 18 to 93 years who were hospitalized with an inter... |
Judging by outcome studies from around the world, most experts agree that one cannot effectively treat anorexia nervosa without first restoring body weight . It is also clear that without a concerted refeeding effort, no meaningful psychotherapy can take place, due to starvation - induced cognitive deficits . However, ... |
Given a real - valued measure of discriminability m(x, y) between stimuli y y and stimuli x x, regular minimality (rm) means that [a] for every x x one can uniquely find a matching stimulus in y, defined as the y y which is least discriminable from x among all stimuli in y; [b] for every y y one can uniquely find a mat... |
Internet is growing worldwide for information and is a user - friendly communication medium that is cost - effective and fast useful tool in education . Today, internet is a global system that is increasingly used by all people as one of the most important devices for access to information in the world, especially youn... |
Osteonecrosis of the femoral head (onfh), of which avascular necrosis comprises the principal part, is a progressive and disabling condition in young and middle - aged patients . Typically, patients are asymptomatic in early stages while eventually requiring a total hip replacement (thr). Morbid vascularity (i.e., thro... |
Although leprosy does not constitute a public health problem in senegal since 1995, it still persists . Each year, hundreds of patients are diagnosed by the staff of the national program for elimination of leprosy (npel) and the institute of applied leprology of dakar (iald). In 2006, there were 353 new cases of lepros... |
Epilepsy is a chronic neurological disorder that affects individuals of all ages regardless of gender . The impact of living with epilepsy can be enormous than the seizure itself . A world health organization (who) report estimated that 10% of the global burden of brain and mental disorders is caused by epilepsy, calcu... |
A 5-year - old boy presented with a large 5 cm 5 cm cyst covering the left eye completely since birth [fig . 1]. A written informed consent was taken from the father of the patient for publishing the clinical photographs . The visual acuity in the right eye was 20/20 with unremarkable anterior and posterior segment fin... |
Evidence is emerging that neurological symptoms in prion diseases precede neuronal loss and are due to an adverse effect of misfolded prion protein (prp) on synaptic function . Therapeutic intervention, therefore, requires identification of the mechanisms by which abnormal prp disrupts normal neuronal activity . Here, ... |
Axin2 mice were obtained from jackson laboratory (city, state, country) and maintained on a c57bl/6 genetic background (charles river, hollister, ca, usa). Animals heterozygous and homozygous for the axin2 allele are here referred to as axin2 and axin2 mice, respectively . Noon on the day of detection of the vaginal pl... |
Infectious spondylitis is commonly caused by pyogenic infection, particularly staphylococcus aureus, which accounts for 60% of all spinal infection . The rate of occurrence of fungal infections has increased over the last decade as the population of immunocompromised patients has increased . Candida and aspergillus spe... |
Cavernoma, also called cavernous hemangioma or cavernous angioma, is a type of blood vessel malformation, which may be considered as a benign brain lesion.1 cavernoma can appear at all ages, mainly occurring in the third to fourth decade of life . It is a rare condition, presenting in 0.5% of the general population . W... |
Epithelial - myoepithelial carcinoma (emc) is a rare glandular epithelial neoplasm of the salivary gland, with an incidence of less than 1 percent of all salivary gland tumors . Emc generally occurs in the parotid gland, but some cases in the maxillary sinus, nasal cavity, trachea, larynx and lacrimal gland have been r... |
Malignant gastrointestinal lymphoma usually originates from the stomach and is mostly derived from b cells and rarely from t cells . We treated a patient with malignant t - cell lymphoma of gastric origin accompanied by chronic tuberculous pyothorax, which required differentiation from gastric metastases of adult t - c... |
This study uses social network and spatial analytical methods simultaneously to understand cholera transmission in rural bangladesh . Cholera is a bacterial disease that has been linked to the aquatic environment and can survive in brackish, coastal, and fresh water environments for significant periods of time [18]. Tr... |
Langerhans cell histiocytosis (lch) is a proliferative disorder of histiocytes in multiple organs . This study describes a seven - month - old iranian girl who presented with skin rash and cervical lymphadenopathy . Langerhans cell histiocytosis was suspected when it was associated with anemia, splenomegaly and lytic b... |
Pulmonary alveolar proteinosis (pap) is characterized by accumulation of surfactant proteins in the alveoli due to defective surfactant clearance by alveolar macrophages . The clinical course of the disease is variable, ranging from respiratory failure to spontaneous resolution . A crazy - paving pattern is suggestive ... |
Between august 2003 and november 2005, we recruited 282 consecutive diabetic patients with an acute foot ulcer who were hospitalized at the german diabetes clinic and 175 diabetic patients without a history of foot ulcer who were admitted to our outpatient unit . Fasting blood samples were drawn on the first day after ... |
The common -chain (c) cytokines include interleukin-2 (il-2), il-4, il-7, il-9, il-15, and il-21 . They have a common feature of sharing c as the signaling subunit of their receptors [13]. Among these cytokines, il-7 is the pivotal cytokine for the generation of t cells in the thymus and homeostasis in the peripheral l... |
Development, differentiation, and homeostasis are controlled by cell - cell interactions, cell - extracellular matrix (ecm) interactions, and soluble cues (hormones, cytokines, and growth factors) [1, 2]. These interactions cause the transduction of many different signals that regulate cellular functions, such as gene ... |
Meniscus injuries are frequently reported concomitantly with acl injury [13]. A recent study of matheny et al . Revealed 3.5% of posterior lateral meniscus root (plmr) tear with concomitant acl rupture . The meniscus roots are the insertions of the anterior and posterior meniscal horns on the tibial plateau [57]. A rad... |
A 5-year old male child was brought to hospital 15 h after ingestion of button (disc) battery of toy . Radiodraph of chest and abdomen erect showed the disc - shaped foreign body in lower one - third of oesophagus [figure 1]. Radiodraph of chest and abdomen erect showing the disc - shaped foreign body in lower one thir... |
Supraclavicular approach to brachial plexus block is routinely used all over the world for surgeries of upper limb because of the anatomical ease of blocking nerve roots at this level of brachial plexus . Over many years many adjuvant drugs like vasoconstrictor adrenaline have been tried with local anesthetics to prolo... |
Lipolytic enzymes catalyse hydrolysis and synthesis of either long - chain (lipases) or short - chain (esterases) acylglycerides . Nowadays, there is an increasing interest in the study of thermostable enzymes not only due to their more thermostability but often due to more resistance to other extreme conditions than t... |
A 67-year - old woman presented with blurring of the left eye . The patient presented with best - corrected visual acuity of count fingers at 2 oculus dexter (od) and 20/40 oculus sinister (os). A relative afferent pupillary defect was observed in the right eye . There were nuclear sclerosis (lens opacities classificat... |
The communication issues in history of civilizations always attract the attention of researchers . In this paper authors analyses the modern role of public health workforce in communication processes in emergencies and present the experiences from international community . The situation is more complicated when additio... |
We report on a 58-year - old caucasian woman that was hospitalized owing to a monstrous ovarian tumor on the right side with a three - month history of sudden abdominal growth and subsequent dyspnea . Sonography and ct scan rendered an additional myomatous uterus with requirement of a bilateral hysterosalpingectomy . T... |
The lung transplant, in contrast with other transplanted organs, can often be infected, notably by respiratory infectious agents . A 40-year - old caucasian woman with a lifelong history of cystic fibrosis was admitted for a progressive respiratory distress upon return by plane from turkey . The patient had noted over ... |
Several prognostic indicators for this cancer, such as tumour size, lymph node status, histological grade and type, vascular invasion and oestrogen receptor status, have been demonstrated . There is, nevertheless, a considerable need for reliable prognostic markers to assist clinicians in the management of this cancer ... |
We obtained peromyscus maniculatus bairdii and p. polionotus subgriseus from the peromyscus genetic stock center (university of south carolina). Laboratory - reared males were weaned at 25 days postpartum, housed individually, then paired with a sexually - mature virgin female at 60 days postpartum for 15 days . We har... |
Peripheral ossifying fibroma (pof) is a relatively uncommon, probably reactive gingival overgrowth . Pofs consist of one or more mineralized tissues, including bone, cementum - like material, or dystrophic calcification within a matrix of cellular fibroblastic tissue . Females are more commonly affected than males, and... |
Periodontitis is a chronic bacterial infection characterized by persistent inflammation, connective tissue breakdown and alveolar bone destruction . Inflammatory mediators and tissue breakdown products have been frequently detected in gingival tissues, gingival crevicular fluid, serum, and saliva . Tumor necrosis facto... |
It is unclear how these commensals regulate immunologic responses to food antigens, but there is mounting evidence that the microbiological environment of the intestine has a profound influence on oral tolerance [15]. In addition to the commensals and pathogens residing in the intestine, food products are often contami... |
Osteosarcoma is the most common primary bone sarcoma representing about 25 - 35% of all cases but constituting only about 0.1% of all neoplasms . A small subset of patients with osteosarcoma may have involvement of multiple skeletal sites without evidence of visceral metastases . Less than 100 cases of synchronous type... |
Stevens - johnson syndrome (sjs) has been an immune - mediated hypersensitivity reaction that involved the mucous membranes and skin in which detachment of 10% of the bsa occurs . Typical prodromal symptoms of sjs were arthralgia, malaise, fever, body aches, headache, fever, epistaxis, and tachycardia, and then complic... |
Suicide is a leading cause of preventable deaths and it is among the top 20 leading causes of mortality globally for all ages . In the last 50 years, suicide rates have increased by 60% worldwide while in india, in just last three decades there is 43% increase . Recent data suggest south india as one of the regions wit... |
Diabetes mellitus is a pandemic disease that has struck each and every corner of the world . According to the indian council of medical research - indian diabetes study (icmr), a national diabetes study the prevalence of diabetes among adults has reached approximately 20% in urban and approximately 10% in rural populat... |
Saccades are the rapid eye movements that we use to explore the visual world . They typically last a few tens of milliseconds, so the ongoing movement cannot use visual feedback for guidance . This means that the size and direction of the saccade are planned before the eyes move and accuracy is maintained based on erro... |
Breast cancer is the most common cancer among women as well as the leading cause of cancer deaths in women . Every year more than one million new cases are detected worldwide . With 502,000 deaths in 2005, the world health organization (who) has introduced breast cancer as the leading cause of cancer deaths among women... |
Karyomegalic interstitial nephritis (kin) is an uncommon hereditary cause of chronic interstitial nephritis described for the first time over 40 years ago . In 1974, burry et al reported a young woman dying from hepatocellular carcinoma and who displayed dysplastic nuclei in the renal epithelium . The term of kin was i... |
In june 2000, a 49-year - old muslim woman was admitted to the hospital with a purpuric rash . She was initially thought to have a hematologic disorder before meningococcal septicemia was suspected . Despite treatment with intravenous penicillin and cefotaxime, she died the following day . A latex agglutination test wi... |
Chronic kidney disease (ckd) has increasingly been recognized as emerging health problem in india . The major contributory factors leading to the development of ckd are diabetes and hypertension . In canada, the u.s centers for disease control and prevention found that ckd affected an estimated 16.8% of the u.s adults ... |
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