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The loss of visual function from glaucoma is directly caused by structural damage to retinal ganglion cells and their axons, resulting in retinal nerve fiber layer (rnfl) loss . Therefore, identifying and assessing retinal nerve fiber layer defects are important for diagnosing and managing glaucoma . Optical coherence ... |
Prenatal care (pnc) is a widely used preventive health service, and it is recognized as being important for the health of pregnant women and their babies . There is an international consensus that the initiation of pnc visits should start during the first trimester of pregnancy . The early initiation of pnc and regular... |
The donor site is limited around the medial canthus, which results in excess skin traction and distortion . Although a basic principle of an eyelid reconstruction is the use of neighboring tissues for matched skin color and texture, medial canthal reconstruction involves two different facial esthetic units: the areas s... |
The diagnosis requires a high index of suspicion and is often delayed; nearly 15% of iatrogenic tracheal injuries from emergency intubations are identified at post - mortem . The recognition that post intubation tracheal rupture (pitr) has a distinct etiology, characteristic pattern of injury and a high perioperative r... |
Federal regulations require hospitals to submit medicare cost reports as a prerequisite to medicare payment . Each participating hospital must submit the report to its designated fiscal intermediary (fi) and must do so within 90 days of the close of the hospital's fiscal year (fy). The fi's receipt of the cost report b... |
Implant placement in the posterior region of the jaw presents great occlusal and surgical challenges [14]. For a successful single - molar replacement, a balance between functional and parafunctional forces and the capacity of the implant to support prosthesis is critical; otherwise, increased load conditions can devel... |
Anastomotic leakage may lead to prolonged hospital stay, reintervention, sepsis, and even death [16]. Besides a very complicated postoperative recovery, anastomotic leakage can have lifelong impact, with a high risk of a permanent stoma and increased risk of fecal incontinence [710]. The current incidence of anastomoti... |
The australian health care system has a fundamental focus on providing access to safe and most appropriate care for the person's health care needs in the timeliest manner . As with most westernized countries, health care reform in australia is warranted in response to demographic shifts resulting in an aging population... |
We recruited 65 subjects who provided informed consent: 33 subjects with type 1 diabetes (13 recently diagnosed [diabetes duration <5 years] and 20 with longer - term diabetes [> 10 years]) and 32 age- and sex - matched control subjects with no cardiac history or diabetes . All subjects were without evidence of coronar... |
S - adenosyl - methionine (same) is a methyl donor that is most commonly used in the treatment of mild - to - moderate depression and osteoarthritis and as a liver - protective agent.1 although its use in serious depression is still controversial,2,3 its involvement in the synthesis of such neurotransmitters as norepin... |
The nutritional benefits of linum usitatissium seed, more commonly known as flaxseed, are of significant interest as flax is seen as healthy . Oil is the main constituent of flaxseed, with more than 70% of the oil composed of polyunsaturated fat . Flaxseed oil is the richest source of the essential omega-3 fatty acid, ... |
Changes in communication, brought about by neurological disorders, are most often defined and described in terms of the individual's impairments of speech and voice (dysarthria) or language (aphasia). Different aspects of speech and language can be measured and quantified using clinical tests and instrumental analyses ... |
Usual interstitial pneumonia (uip) is the most common of the idiopathic interstitial pneumonias (iips).1 uip can be idiopathic (idiopathic pulmonary fibrosis, ipf), may be secondary to certain inhalational exposures and medications, or occur in the context of connective tissue diseases (ctds). The detection of uip on l... |
The list of prokaryotic names with standing in nomenclature (lpsn), available at http://www.bacterio.net, was established in 1997 as the of list of bacterial names with standing in nomenclature (lbsn), which was available for downloading via an ftp server (1). It subsequently was published online on 28 january 1998 and... |
Blind individuals compensate their lack of visual input by improving sensitivity to auditory or somatosensory inputs . This type of plasticity is known as cross - modal plasticity [1, 2]. Although dynamic cortical reorganization among different sensory areas seemed to be critical for cross - modal plasticity, the molec... |
Since its introduction in 1973, x - ray computed tomography (ct) has revolutionized medical imaging and become a cornerstone of modern radiology . Improved resolution and reduced dose are two critical requirements in biomedical applications and remain the focus of ct research and development . The rapid development of ... |
It is a common gynecological condition that affects up to 22% of all women, 8 - 15% of women of reproductive age and 6% of premenopausal women . Most of the reported cases occurred in gynecologically induced abdominal or pelvic scars, including hysterectomy, episiotomy, caesarean section and laparoscopy . It is extreme... |
Several factors affecting bile content and bile flow are involved in the complex pathogenesis of gallstones . In hypothyroidism, not only the risk for gallbladder stones [1, 2], but also the risk for common bile duct (cbd) stones in particular is increased [35]. Impaired liver cholesterol metabolism, diminished bile se... |
However, progression of the scoliotic deformity after posterior spinal fusion has been described [14]. Various etiologies for loss of correction have been proposed, including pseudarthrosis, implant failure, incorrect selection of fusion levels, adding - on, biologic plasticity of the fusion mass [6, 7], and the cranks... |
Despite major progress in the treatment of acute stroke it remains one of the most devastating neurological conditions and substantial economic costs are incurred due to stroke - related disability . Cardiac complications such as arrhythmias, ischemic heart injury, or sudden death resulting from cardiovascular autonomi... |
This study was conducted at the national taiwan university hospital (ntuh), a 2,500-bed tertiary medical center in northern taiwan where 8,000 clinical visits occur daily . We evaluated all patients registered in the hospital s mycobacterial laboratory database with cultures positive for ntm or m. tuberculosis during 2... |
Field emission is quantum mechanical tunneling of electrons through the surface potential barrier into vacuum, which has been widely exploited in vacuum electronic applications including electron guns, microwave tubes, and flat panel displays . Vertically aligned nanowire array (vana) shows excellent field emission pro... |
Ocular biometry is an essential procedure in ophthalmology as it is used to calculate the optical power of the intraocular lens (iol) that replaces the cataract lens in pseudophakic cataract corrections.1,2 an integrated component of optical biometry is accurate measurement of the axial length (al) of the eye, the most... |
Image 1specificationsorganism / cell line / tissuehomo sapiens / hesc line hues6/differentiating human embryonic stem cellssexfemalesequencer or array typehumanht-12 v4data formatraw and processedexperimental factorsvariation of cell signaling factor stimulation; time - course expression profiling at daily intervals du... |
Driving ability of older drivers is reduced due to the overall dysfunction involved in the natural aging process1 . Almost half of all drivers are older, and their accident rate has continued to increase2, 3 . Therefore, recently, elderly driving experts have committed to the screening of at - risk older drivers to pre... |
We purchased 14 different type of human cancer human tissue microarray sections (lung, 49; breast, 49; thyroid, 10; pancreas, 10; gallbladder, 9; larynx, 9; esophagus, 10; liver, 10; cervix, 10; ovary, 10; stomach, 10; prostate, 9; kidney, 9; and endometrium, 9 sections) and normal tissues (lung, 9; breast, 8 sections)... |
A 42-year - old woman presented with a history of 15 days of short - term memory loss . She complained of generalized weakness and voice changes over the previous 3 months . On physical examination, she had mild bilateral ptosis . Chest x - ray revealed a right hilar mass and chest computed tomography showed a 5 cm ant... |
Biology's entry into the genomic era during the past decade has led to new scientific challenges concerning not only the characterization of organism's genomes, but also their expression levels . Among the various types of investigations supported by dna microarray technologies (17), transcriptome analyses are the most... |
Endoscopic surgical techniques are now enabling the repair of select complex congenital anomalies such as diaphragmatic hernia . Despite the target organ system for repair we are currently developing a minimally invasive vesicostomy model for the in utero treatment of obstructive uropathies . Prenatally diagnosed fetal... |
Ovarian cancer remains a major health problem worldwide, with over 225,000 new cases and 140,000 deaths reported annually.1,2 symptoms associated with ovarian cancer are often nonspecific, and the majority of patients continue to present with advanced disease, where the cost of treatment is high and the survival rate i... |
Modern public health practice still lacks strong political support.1 neither managers nor public health professionals appear to be succeeding in their attempt to improve the health of the public . This is evidenced by the enormous waste of resources on downstream interventions because of the absence of work upstream . ... |
The relationship between various work - related conditions and health outcomes is well - documented especially in the united states and europe . A classical study by karasek1 advocates the job strain model which claims that demanding work conditions and a lack of autonomy in decision - making at workplace lead to deter... |
Hypertension is a progressive cardiovascular disease that arises from many differing but inter - related etiologies . Early markers of the syndrome are often present before there is a sustained rise in blood pressure (bp) elevation . Hypertension therefore, cannot be classified solely using discrete bp parameters [1, 2... |
Insects cause economically important damage on crop yield by direct feeding damage, defoliation, and transmission of plant viruses . Although biological control methods have been developed for some insect species (daz et al ., 2012), chemical insecticides, based on varying modes of action, are still used in large quant... |
Benign intracranial tumors, with exception of pituitary adenomas, rarely present with a hemorrhagic event . While hemorrhage in most intracranial tumors like gliomas and metastatic lesions will present as intracerebral hemorrhage, the peculiarity of hemorrhagic transformation in meningiomas is that such hemorrhage may ... |
Paraquat (1,1-dimethyl-4,4-bipyridilium dichloride, pq) is a widely used contact and nonselective quaternary nitrogen herbicide . It was first introduced in agriculture in 1962 and has caused thousands of human deaths, either by accidental or voluntary ingestion . The toxicity of paraquat is based on its induction of r... |
Periodontal disease, including gingivitis and periodontitis, is considered to be one of the most common diseases among population and, if left untreated, can lead to tooth loss . The main cause of periodontal disease is bacterial plaque although many other factors such as hormonal changes, diabetes, poor nutrition, smo... |
The physiological balance of sera in neurocritical patients can be easily destroyed after a major surgery such as decompressive craniectomy . The course of coagulopathy due to major bleeding during and after the surgery would accelerate the imbalance of acid - base equilibrium of our blood.16) biomarkers such as arteri... |
Demyelinating diseases, such as multiple sclerosis (ms), the major demyelinating disease of humans affects not only young adults, but also children . It is the leading cause of neurological deficit in north america and western europe . It is characterized by the patchy destruction of the myelin sheath around the axon a... |
Palatal rugae are transverse ridges of the mucosa located at the upper jaw, on the anterior portion of the hard palate . The number, shape, width, height, and location of palatal rugae vary from the left side of the palate to the right side as well as from one person to another, and are unique to every individual . Pal... |
Bacterial chemotaxis is one of the best - studied signal networks in biology, having been exhaustively investigated with genetics, biochemistry, and mathematical modeling (1). Hence, it is exciting when a brand - new player in the process is discovered . In the july / august issue of mbio, howitt and colleagues (2) des... |
Dental fear / anxiety and behavior management problems in pediatric patients are two major aspects of uncooperativeness in pediatric dentistry . Whilst psychological techniques are the cornerstone of behavior management in pediatric dentistry, a number of children cannot cope with dental treatment using these technique... |
A dentistry drill was used to remove two samples of bone powder from an area where a larger sample had previously been removed for carbon dating . Two extracts (e1406, e1843) were prepared from 25 mg and 10 mg of bone powder, respectively, as described . Five libraries were produced from the two extracts using a single... |
It is not unusual for women to suffer from osteoporosis and breast cancer after menopause1,2,3,4 . The incidence of these two diseases has been reported to be related to estrogen levels . Since estrogen stimulates the mitosis of breast cells, it can also promote the occurrence and growth of breast cancer . Estrogen lev... |
Ms is an important health concern due to its relation with increased risk of coronary heart disease (chd). However, other factors such as genetic predisposition, ageing, and physical inactivity are also implicated in its development (1, 2). Developing societies experience an increasing trend in the prevalence of ms wit... |
Ioct may be used in both full - thickness and lamellar keratoplasty procedures as an aid to decision - making . In penetrating keratoplasty, ioct helps to delineate the anterior segment architecture in cases with extensive synechiae or corneo - iridic scars and help avoid iris trauma during initial trephination . The g... |
Based on an article by the who, mortality of children under 5 years has decreased up to 5% while noncommunicable diseases (ncds) mortality has increased from 59% in 2002 to 69% of deaths in 2003 . Moreover, a significant increase in hiv mortality from 2.8 million to 6.5 million and a rapid change in smoking mortality f... |
Acl ruptures are a common injury in orthopaedic practice . The acl is frequently replaced by a tendon autograft or allograft to restore normal knee laxity and to prevent the development of early osteoarthritis induced by persistent abnormal laxity . Reconstruction techniques were improved over the last 10 years, but gr... |
This surveillance project was a collaboration between mexican public health officials, nongovernment organizations, and the university of california, san diego (ucsd). The project was approved by the institutional review boards of tijuana general hospital and ucsd . Our binational research team of us and mexican resear... |
The driving forces and resulting pathways governing the transition of proteins from their unfolded state to their native state remain unanswered fundamental questions for biophysics . As the misfolding of proteins has been associated with a number of diseases, the understanding of the folding process has important pote... |
Elderly acute myeloid leukaemia (aml), generally defined as aml in a patient who is more than 60 years of age, is a clinical entity distinct from the aml in younger adults or children . Unlike in younger adults with aml in which the treatment is straightforward and the goal is cure with intensive chemotherapy, treatmen... |
, more than 240 million people with hbv infection and 150 million people with hcv infection, have chronic liver infections worldwide (2, 3). There were approximately 35.3 million people infected with hiv in 2012 (4), and 10% of the patients with hiv infection in europe and america are co - infected with hbv, and almost... |
On an international scale, access to palliative radiotherapy varies with geographic region, health care system, and sociodemographic factors [1, 2]. The presence of waiting lists might cause distress, unnecessary symptom burden, and under certain circumstances compromised outcomes, at least if long waiting time is unav... |
The gonadotropin releasing hormone (gnrh) neurons are central to sexual and behavioral maturation and the control of gnrh secretion is fundamental to reproductive maturation . The gnrh neurons are the fundamental regulator of the pulsatile release of gnrh required for puberty and fertility . The root of ginseng (panax ... |
A 64 year old male presented with exertional breathlessness progressing in severity over six months . He had been diagnosed to have dilated cardiomyopathy with non sustained atrial tachycardia and ventricular tachycardia elsewhere and advised implantation of a defibrillator . Review of electrocardiograms showed recurre... |
A cholesterol granuloma consists of fibrous granulation tissue containing cholesterol crystals that are surrounded by foreign body giant cells; the occurrence of this disease in the breast is very rare . It is not difficult to distinguish a cholesterol granuloma from a breast carcinoma on histological examination; howe... |
Since first described in 1964 there were several case reports of classical sweet's syndrome and sweet's syndrome complicating infections or medications in the medical literature . Sweet's syndrome in human immunedeficiency virus infection (hiv) is extremely rare and until date, there are only few case reports . To the ... |
A 35-year - old male patient presented with a swelling of the right upper eyelid of 10 years duration . The swelling which was initially the size of a peanut started increasing in size since the last 1 year, causing drooping of the upper eyelid . There was no history of ocular trauma, previous surgery or any systemic i... |
Wegener's granulomatosis (wg), which has been recently renamed as granulomatosis with polyangitis (gpa) is a systemic vasculitis involving small and medium vessels . Although classical gpa presents with a triad of upper respiratory tract, pulmonary and kidney involvement, uncommonly patients with atypical presentation ... |
Mental illness is a global public health concern . According to the world health organization, one out of four (25%) the prevalence of mental disorders is higher in developed countries, but the global burden of untreated mental disease is higher in developing nations . Eighty percent (80%) of the population suffering w... |
Regardless, one of every three humans is infected with the tb pathogen . According to the world health organization (who), 7.1 billion people worldwide are infected with tb and more than 20 million people suffer from active tb . Annually, more than 8 million people are infected with tb and about 3 million tb patients l... |
Relevant published english - language articles were identified by searching the medline database (national library of medicine, bethesda, md), embase, and cochrane reviews (the cochrane collaboration) through march 2010 and by a manual bibliography check . The medline search was as follows, with similar terms for other... |
To report visual and anatomic outcomes of chronic macular hole surgery, with analysis of pre - operative oct - based hole size and post - operative closure type . An irb - approved, retrospective case series of 26 eyes of 24 patients who underwent surgery for stage 3 or 4 idiopathic chronic macular holes at a tertiary ... |
Deoxyribozymes are catalytic dna oligonucleotides (1,2) derived by in vitro selection (3,4). They are not only convenient models for studying nucleic acid catalysis, but are also suited for biotechnological applications . The advantages offered by catalytic dnas include high chemical stability (5), low cost of synthesi... |
The most common human diseases have a complex aetiology involving both genetic and environmental factors . Genome - wide association studies (gwas) applying a selected set of single nucleotide polymorphism (snp) covering the entire genome have recently become popular and quite successful methods in search for genetic d... |
In 1994, the congress of the international federation of gynecology and obstetrics (figo) defined stage ia1 squamous cell carcinoma of the cervix as microscopic tumor with stromal invasion no greater than 3 mm in depth and 7 mm in width . The standard treatment for this stage of disease consists of a complete removal o... |
Image 1organism / cell line / tissuestreptococcus pneumoniae d39sexn / asequencer or array typeoligo - based dna microarraydata formatraw and processedexperimental factors5 mm versus 0 mm aspirinexperimental featuresaspirin - dependent gene expression was explored by microarray comparison of s. pneumoniae d39 wild - ty... |
We report a rare patient who developed cerebellar ataxia and optic neuritis following recovery from plasmodium vivax (pv) malaria, which is usually a mild and uncomplicated disease compared to plasmodium falciparum (pf). Furthermore, we discuss the differentials of malarial neurological manifestations and the possibili... |
The second leading cause of blindness worldwide is glaucoma, which involves optic neuropathy and the progressive loss of the retinal ganglion cells (rgcs), resulting in visual field defects (1). Depending on its etiology and the dynamics of the aqueous humor, glaucoma is classified into primary and secondary categories... |
Classically, it is believed that adaptive helper t (th) cells underlie the pathogenesis of multiple inflammatory skin disorders such as atopic dermatitis (ad) (bieber, 2008) and psoriasis (nestle et al ., 2009). For example, t helper type 2 (th2) cells produce hallmark type 2 cytokines il-4, il-5 and il-13 are believed... |
A previously healthy 38-year - old caucasian female sought medical attention because of excoriated acne . A small, pigmented papule in the malar region of unknown duration was incidentally noted during physical examination (figure 1). Dermatoscopy revealed some structures resembling brownish ovoid nests indicating the ... |
Metastasis to the oral cavity rarely occurs and constitutes 1% of all oral cavity malignancies, and has mostly been found in the jaws compared to the soft tissues . Metastasis to the jaw bones mainly occurs in the posterior region of the mandible, ramus, and the condyle, which are rich in red bone marrow . Metastasis t... |
Myeloid sarcoma (ms) is a tumorous aggregate of malignant immature granulocytes, monocytes, or both involving any extramedullary site . Although first described by burns in 1811, it was king in 1853 who coined the term chloroma based on the green color of the tumorous mass attributable to the enzyme myeloperoxidase . M... |
Unfortunately, the nomenclature and the classification of these tumors are complex and not consistent over a period of time . The complexity and the inconsistency in its classification have resulted in usage of a large number of terms and classification systems, resulting in confusion in understanding the pathophysiolo... |
Work at young ages could give rise to plenty of physical and mental disorders . During industrial revolution, materialistic and inhumane abuse of children left abject conditions in industrial societies (1). Child labor refers to forcing children to work at the age of childhood, i.e. Children under 14 years old (2). The... |
Guillain - barr syndrome (gbs) is an autoimmune inflammatory peripheral neuropathy disease, which results from an aberrant organ specific immune response that affects primarily the myelin sheath of the proximal portion of peripheral nerves . In approximately 60 - 70% of patients, gbs is triggered by a preceding acute d... |
This mediation is done through preventive services they provide to their children such as dietary habits supervision, oral hygiene performance and other practices . In this context, the important role of mothers in establishing lifelong positive attitudes and behaviors has been documented . Infancy and toddlerhood are ... |
We tested well - defined risk groups for hiv and parenterally transmitted infections to more precisely determine the transmission route of parv4 . Autopsy tissue samples used in this project were obtained from the edinburgh medical research council (mrc) hiv brain and tissue bank at the western general hospital, edinbu... |
The ubiquity of computers in our lives is undisputed . For every modern - age college student it is virtually a must to own or have access to a computer for him or her to succeed in course work . Almost every assignment in today's classroom requires some computer work, be it researching literature, performing calculati... |
It is related to vehicles that physically carry a computer with a storage device and a limited telecommunication module (usually wi - fi) between remote areas in order to effectively create a data communication link . A delay - tolerant network (dtn) is an architecture that provides a common method for interconnecting ... |
Men are affected twice as commonly as women, with peak incidence being at 30 years of age . Ureteral stones contribute to 20% of all urinary tract stones, 70% of which are located in the distal ureter . Fifty percent of patients have a recurrence of renal colic within 5 years of the first episode . Medical expulsive th... |
Congenital nasolacrimal duct obstruction (cnldo) occurs in up to 70% of neonates at delivery . However, only 6%20% of all neonates have symptoms, because the obstruction usually resolves spontaneously before lacrimal secretion begins.1 the main presentation of nasolacrimal obstruction is watering (epiphora) and mucopur... |
In recent years, polymerization - induced self - assembly (pisa) has become a widely recognized route for the synthesis of many types of diblock copolymer nano - objects . Compared to post - polymerization processing techniques (solvent exchange, film rehydration, or ph switch), pisa is much more efficient and this app... |
Breast cancer, with the incidence of 2% annually (1), is one of the most common malignancies among iranian women (2) and the lowest mean age in the middle east (3). Although its treatments such as surgery, radiotherapy, chemotherapy and hormonal therapy reduce mortality rates of breast cancer, each may lead to differen... |
Although patients with interstitial pulmonary fibrosis or pulmonary arterial hypertension can have normal spo2 at rest, some will show oxygen desaturation after submaximal exercise . (,) end - exercise pao2 decreases after maximal exercise, and submaximal steady - state exercise was found to be an important measure of ... |
Diabetic microvascular disease, one of the most important complications in diabetes mellitus (dm), has been considered a major cause of health impairment world - wide . Many biochemical mechanisms have explained the structural and functional abnormalities associated with overexposure of the vascular tissues to hypergly... |
Supplementary material is available for this article at 10.1007/s13659 - 011 - 0023 - 7 and is accessible for authorized users. |
Copd is a respiratory disease characterized by progressive and partially reversible airflow limitation, which results from an emphysematous destruction of the lung parenchyma and increased airway resistance due to inflammation, bronchospasm, and increased mucous production.1 there is an increasing need for awareness re... |
Autoimmune pancreatitis (aip) is a benign disease that was first reported in 1961 . It can occur as a primary disease of the pancreas (type 2) or as part of a systemic disease produced by igg4-positive lymphoplasmacytic infiltration of the involved organs associated with elevated igg4 blood levels (type 1). Aip - induc... |
Type 2 diabetes mellitus (t2 dm) is becoming a common worldwide disease with epidemic proportions in many populations . Environmental changes promoting unhealthy behaviours and development of obesity and overweight around the world have been suggested as the principal causes . In addition, related diabetes complication... |
It has been well accepted that hypercholesterolemia is a major risk factor for coronary heart disease . On the other hand, some previous studies [25] observed that hypocholesterolemia was associated with a significantly increased risk of lung cancer . To our knowledge, there is only one previous study that investigated... |
They are opportunistic and associated with some health - related infections (1, 2). Such bacterial infections, particularly in patients hospitalized at intensive care units, are very dangerous (3). In addition, colonization rates are rising among hospitalized patients, especially those hospitalized for a long time or t... |
Interleukin-33 (il-33) is a recently described member of the il-1 family, which includes il-1, il-1, il-18, and il-1ra . Interleukin-33 is the ligand of the st2 receptor, also termed t1, t1/st2, st2l, st2-rs1, der4, fit-1, ly-84, or il-33r, a member of the toll - like receptor / il-1r superfamily [3, 4]. It was initial... |
Inducing apoptosis in tumor cells is a promising therapeutic approach for the treatment of both solid and lymphatic tumors . The tnf family member tumor necrosis factor - related apoptosis - inducing ligand (trail) is an apoptotic mediator that has received much attention, due to its ability to bring about cell death s... |
It is well known that dental caries is a multifactorial infectious disease caused by aciduric and acidogenic bacteria that is a major oral health problem affecting 6090% of schoolchildren and also adults.1 since the 19 century, the best practice in treating dental caries has been physical amputation of softened tissue ... |
Computed tomography (ct) has emerged as an important diagnostic tool in clinical medicine . Its use has grown exponentially over the years, rising from 3 million in 1980 to 67 million in 2006, an equivalent of a 600% increase from 1980 to 2006 . This significant rise in frequency also brings into question the level of ... |
Dr . Potenza reports no conflicts of interest with respect to the content of this manuscript . Dr . Potenza has served as a consultant or advisor to boehringer ingelheim, somaxon, lundbeck, ironwood, shire, insys, rivermend health, and various legal and gambling entities on issues related to impulse control disorders .... |
Armchair - type swcnts, along with zigzag and chiral carbon nanotube structures [16], are important for both basic science studies and practical applications (e.g., in modern material science). Single - wall carbon nanotubes are frequently referred to as one - dimensional structures due to their nanoscale dimensions an... |
Chronic respiratory diseases have never, in any area of the world, been accorded a priority relative to their extent and impact . No political jurisdiction (rich or poor) proportionally commits resources to chronic respiratory diseases equivalent to the burden they represent in the community, whether for research, prev... |
To determine the physiological functions of mcu, we constructed a mouse model using a gene trap strategy in which a retroviral trapping vector was integrated into the first intron of the ccdc109a locus (supplemental fig . 1a, b), organ weight was proportional to body size and overall body composition was indistinguisha... |
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