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In spite of precautions, a foreign body retained in the abdominal cavity after surgery may lead to persistent problems such as adhesions, perforation, and abscess or fistula formation (123). Endoloop ligature (ethicon, somerville, nj, usa) is surgical instrument to facilitate the ligation of pedicles in laparoscopic pr... |
This study included 51 hypermetropes (25 males and 26 females) with brown irides who attended the strabismus service, and were approved by our institutional review board . The age of the 51 patients ranged from 6 to 20 years (mean, 12.48 3.76). 1 . A total of 41 (80%) patients had esotropia, 6 (12%) had exotropia, and ... |
A 63-year - old male experienced decreased vision in his left eye for several weeks; he had no history of ocular trauma . His vision was 0.00 logmar and 0.80 logmar in his right and left eyes, respectively . Spectral domain optical coherence tomography (oct; cirrus, carl zeiss meditec, dublin, ca, usa) of the left eye ... |
Polycyclic aromatic hydrocarbons (pahs) are a class of ubiquitous environmental contaminants formed by incomplete combustion of organic material . The main sources of human exposure include occupation, passive and active smoking, food, water, and ambient air pollution . Children may face increased vulnerability to envi... |
One of the key aspects of maternal care is observing labor progress; and lack of labor progress is one of a couple of causes for converting to cesarean operations . Therefore, focusing on the labor progress is very important in the decision to intervene in normal vaginal delivery (1, 2). There are several methods for a... |
Consequently, signal transduction pathways are vital to an organism's survival and function . In microorganisms, they control the majority of cellular functions including chemotaxis, respiration, development, osmoregulation, transport, metabolism, virulence, host - recognition and antibiotic resistance . Such signal tr... |
Esthetic demands have increased among patients, and they prefer to have well aligned and white teeth, showing their health and youth . Tooth bleaching and orthodontic therapy are common treatments that patients seek to have beautiful smiles . Various methods of bleaching have been introduced using different materials, ... |
It is estimated that over 1.5 million new cases of cancer occur each year in the united states . Roughly 500,000 people die each year in the united states from cancer - related causes, most of whom have metastatic disease . The three most common cancers, lung, breast, and prostate, all commonly spread to bone, and the ... |
Although spinal tuberculosis (pott's spine or intradural extramedullary tuberculoma) is relatively common in developing countries, spinal intramedullary tuberculoma (simt) is rarely seen25). Since it was first reported by cascino and dibble4) in 1956, there have been only occasional case reports . In 2002, sharma et al... |
To generate splice variant cav1.342a, the alternatively spliced exon 42a was introduced into cav1.3 cdna (cav1.342 = human cav1.38a as in ref . 4, genbank accession number eu363339) by co - ligating an ecori - bamhi - cut pcr product containing exon 42a from a rat brain 1 subunit (genbank accession number m57682) with ... |
The world health survey indicated that in india the prevalence of psychosis was between 0.7% and 3.6%, while the treatment rates were only 36 - 85% . In addition to the high mental health burden and large treatment gap of mental disorders there are significant limitations in the availability and integration of mental h... |
Cells, viruses and animals: na cells and bhk cells were maintained in dulbecco s modified eagle s medium (dmem; gibco, carlsbad, ca, u.s.a .) Supplemented with 10% fetal bovine serum (fbs), 100 u / ml penicillin and 100 g / ml streptomycin (hyclone, logan, ut, u.s.a .) At 37c . The rabv virus standard (cvs)-11 strain w... |
A large ensemble gives high predictability of the subpolar gyre temperaturethe recently observed cooling is forecast to continueimpacts are numerous, reduced numbers of tropical storms are clearest a large ensemble gives high predictability of the subpolar gyre temperature the recently observed cooling is forecast to c... |
Endoscopic submucosal dissection (esd) is an effective procedure that allows the en bloc resection of premalignant lesions and early gastric cancer (egc) in the stomach.1 - 3 however, esd is technically difficult and time consuming.4,5 major complications of esd are bleeding and perforation and its complication rate is... |
Currently, co - cr alloys are extensively used in prosthodontics due to a combination of favourable properties in a variety of applications in fixed and removable restorations.1,2 however, joining of co - cr dental frameworks is often necessary to repair broken restorations3 or to achieve a passive fit of cast framewor... |
Polymorphisms in sex - linked genes have been reported in a wide range of species (dawson et al . 2001; jarvi and farias 2006; bantock et al . Recently, however, polymorphisms in the chd1 gene have been linked with fitness in common moorhens (gallinula chloropus; lee et al . 2002) and black - tailed godwits (limosa l. ... |
The causative agent of melioidosis in humans is burkholderia pseudomallei which is a facultative intracellular pathogen . This organism is a polar flagellated gram negative bacterium that can infect both humans and animals [13]. The major regulatory control mechanisms for the expression of genes including virulent gene... |
Hemodialysis (hd) patients usually experience relatively high mortality rates; for example, approximately 23% per annum in the u.s ., 15% in europe and 9% in japan . As the most common treatment of advanced kidney failure, hd typically requires patients to follow a strict treatment schedule, which typically entails rec... |
Osteoarthritis (oa) is among the diseases with the highest rates of comorbidity.1,2 comorbidity can be defined as any distinct additional clinical entity that has existed or that may occur during the clinical course of a patient who has the index disease under study.3 common comorbidities in oa include cardiovascular d... |
Psoriasis is a common inflammatory disease affecting more than 25 million people in north america and europe . It is associated with arthritis, myopathy, enteropathy, spondylotic joint disease, and atopic dermatitis . This disease is characterized by well - demarcated lesions on the skin of the elbows, knees, and scalp... |
A 70-year - old female with a past medical history significant for diabetes mellitus, peripheral neuropathy, charcot neuroarthropathy, hypertension, hypercholersteremia, and renal insufficiency initially presented with an unstable charcot joint about the rearfoot and ankle with two draining sinus tracts from the medial... |
Multiple myeloma (mm) is one of the hematologic malignancies with a poor prognosis, characterized by a neoplastic proliferation of monoclonal plasma cells . High - dose melphalan with autologous stem - cell transplantation improves overall survival (os) in patients with mm, who are <65 years old . However, because myel... |
Exhaled breath condensate (ebc) is a simple, noninvasive technique for monitoring airway inflammation . The measurement of eicosanoids in the expired breath condensate has proven to be a useful noninvasive method for the assessment and monitoring of airway inflammation in inflammatory diseases such as asthma and other ... |
Tusc was co - expressed with gst - spc110p as described13,21, except that complexes were eluted by cleavage of the gst tag with tev protease as the final purification step . Tusc rings were formed by 30 minute incubation on ice after dilution to 0.2 m in brb80 (80 mm pipes ph 6.9, 1 mm egta, 1 mm mgcl2). The cryo - em ... |
Total hip arthroplasty (tha) remains controversial in active tuberculosis (tb) infection because of the risks of septic loosening and reactivation of the infection . We present a rare case of tha in a patient positive for the human immunodeficiency virus (hiv) with active tuberculous coxitis . The patient was a 53-year... |
The natural course of aortic stenosis (as) is characterised by among others cardiac arrhythmia and sudden death in up to 34% of the patients. Surgical aortic valve replacement (avr) has shown to reduce the risk of sudden death . Whether this also holds for patients who undergo transcatheter aortic valve implantation (t... |
The international pilot study of schizophrenia estimated that 70% of schizophrenia patients suffered from hallucinations . 25 - 30% of the auditory hallucinations in schizophrenia are refractory to traditional antipsychotic drug treatment . Even with the advent of newer antipsychotics, a significant minority of patient... |
Iga nephropathy (igan) is the most common form of chronic glomerulonephritis for individuals of european and asian descent [1, 2]. The level of proteinuria at diagnosis of igan has been associated with the primary endpoint of outcome (i.e., progression to chronic dialysis or transplantation) in adults [37] and children... |
It is well - known that parkinson's disease (pd) is the second most common neurodegenerative disease in the elderly; however, the etiology of pd remains unclear . Recently, the role of concurrent medical problems has been a major concern surrounding pd . Cerebrovascular disease such as cerebral ischemic lesion (cil) is... |
Granuloma faciale (gf) is an uncommon, benign chronic skin disease of unknown origin characterized by single or multiple, soft, erythematous to livid papules, plaques, or nodules usually occurring on the face, often with follicular accentuation and superficial telangiectasias . Sites of predilection include nose, peria... |
Sebaceous carcinoma (sc) is a rare malignant tumor originating from adnexal skin structures . Most of these malignancies develop in the head and neck area, notably in the eyelid . Other sites include the parotid and submandibular glands, the external auditory canal, the trunk or the limbs . Tumors of this type commonly... |
The discovery that the potent tumorigenicity of transforming avian retroviruses is caused by capture of cellular oncogenes led to the identification of the protooncogenes c - myc and src, among others . An alternative tumorigenic strategy is used by dna tumor viruses, such as sv40 virus and human papilloma virus, which... |
When it comes to drug therapy, intensivists have plenty of decision making every day including drug selection, dosing, administration, and monitoring strategies to optimize effective pharmacotherapy . Even though the patient receives appropriate drug, a suboptimal dose or overdosing may result in either therapeutic fai... |
A previously healthy nine - year - old girl of 47 kg was successfully treated with penicillin v for the diagnosis cutaneous borrelia infection . Six months later (january 24, 2007), fever, headache and a small wound on the left foot without any known trauma appeared . (january 25, 2007), inflammation and lymfangitis in... |
Hepatitis b virus (hbv) infection still constitutes a major problem of public health since 360 million people worldwide are chronically infected and exposed to a progressive disease that may lead to liver cirrhosis and hepatocellular carcinoma (hcc). Hbv surface antigen (hbsag) is the established serological marker for... |
Psychophysical data suggest that number is represented as a point on an analog mental number line . For example, rats or humans asked to produce n responses or estimate n events do so with less precision as n increases (platt and johnson, 1971; whalen et al ., 1999). In addition, the variability of responses increases ... |
Conventional cavity preparation and direct bonding is an acceptable clinical procedure in operative dentistry . To achieve effective adhesion between dental tissue and restorative materials, the smear layer which is formed during removal of dental caries must be either removed or modified . Traditionally, after cavity ... |
The emergence of human language is generally seen as one of the major transitions in the evolution of the organic world: the defining characteristic of the human species [24] or at any rate a crucial twist within it [57]. The issue is not without controversy, as linguistic abilities have been argued to be present in ot... |
According to the original protocol proposed by brnemark, dental implant can be installed in a complete healing state after tooth extraction, and this procedure takes about 6 to 12 months.1,2 however, it was reported that the alveolar bone loss occurred in 23% during the initial 6 months after extraction and additional ... |
Kaposi sarcoma (ks) is a lymphoangioproliferative disease caused by human herpes virus 8 (hhv-8). Early ks seems to be a reactive process of polyclonal nature, which may remain so or progress to become a true sarcoma . Acquired immune deficiency syndrome (aids)-ks may have an unpredictable clinical course varying from ... |
Push - ups are used for many purposes, including strengthening the upper body, rehabilitating the shoulder, stabilization training of dynamic joints, and improving proprioceptive feedback mechanisms1, 2 . Among the various exercises that are generally used to strengthen the shoulder and upper extremity muscles, the pus... |
Total hip arthroplasty (tha) is an effective intervention for patients with severe hip disease and has been shown to lead to marked improvement in health outcomes (1). Because of the significant benefits realized with tha, utilization rates for this procedure have been increasing in most western and asian countries, in... |
The c-19 methyl - substituted indole alkaloids represented in figure 1 are a relatively rare class of alkaloids belonging to the sarpagine ajmaline series with over 17 members isolated to date . In addition to the asymmetric centers at c-3(s), c-5(s), and c-15(r) of the sarpagine / ajmaline framework, these alkaloids s... |
We report a case of an adolescent who sustained flash burns after the foaming bath soap she was using was exposed to a naked flame, causing flash burns to her face, neck, chest and arms . Pressurized aerosol cans, such as deodorants, air - fresheners and insecticides have been reported to cause burn injuries after expl... |
Rapid intra - hepatic dissemination of hepatocellular carcinoma (hcc) is a rare but known occurrence after radiofrequency ablation (rfa) of solitary hccs (1 - 4). The exact incidence is unknown but it is believed to be underreported, and the mechanism of spread remain elusive (1 - 4). We hereby report a case of rapid i... |
Localization of the primary motor cortex is an important neurosurgical consideration when treating lesions in the motor area.1 a major problem in the preoperative planning of surgery for central lesions is the exact assessment of the spatial relationship between pathology, function, and anatomy.2 the symptoms of cavern... |
Periodontal disease affects adolescents and young adults in varying degrees worldwide. [14] dental students are representative of the educated, urbanized, influential, and motivated class of individuals . The effect of joining a dental profession and its relationship with the personal level of oral health has not shown... |
Characterized by irreversible airflow obstruction, which is usually progressive, copd worsens as a result of inhalation of smoke and noxious gases . 1 this disease, which is preventable and treatable, has various systemic manifestations, such as skeletal muscle dysfunction related to decreased exercise capacity, which,... |
Ischemic colitis is an inflammatory disease caused by the lack of colonic blood supply.1,2 being one of the most common form of intestinal ischemias, ischemic colitis is manifested with unspecific clinical symptoms such as acute abdominal pain, diarrhea, or hematochezia . The major causes include hypotension due to deh... |
The management of multiple fragment axis fractures and unstable atlas fractures is still challenging for the spinal surgeon . There are no published reports of similar fractures with 3-part fracture of axis associated with an unstable atlas fracture . We present a patient with concurrent axis and atlas fractures, which... |
Methods and any associated references are available in the online version of the paper at http://www.nature.com / naturegenetics/. |
Accordingly, minimally invasive means to treat patients with aortic stenosis have been recently developed, including self - expandable or balloon - expandable aortic prostheses enabling transcatheter aortic valve implantation (tavi). The evidence base on these novel technologies has accrued recently, thanks to the comp... |
Prostate cancer is the most common malignancy in men, with an estimated incidence in the united states of 241,740 cases and 28,170 deaths in 2012 (surveillance, epidemiology and end results [seer] stats).1 low - dose rate (ldr) brachytherapy has been an effective form of definitive therapy for low - risk localized pros... |
We retrospectively reviewed our institutional database for liver mris conducted between january 2004 and september 2006 on patients suspected of having liver malignancy based on clinical and prior ct findings . We identified 391 patients with hccs and 55 patients with liver metastases who underwent a double contrast mr... |
An 84-year - old gentleman was referred to the urology department at bedford hospital with a computed tomography (ct) scan revealing multiple polypoidal lesions in the urinary bladder (fig the patient initially presented to the dermatology department in may 2010 with a suspicious, raised nodular lesion on the skin of h... |
Pulmonary trauma, severe infection as well as hemorrhage can result in acute lung injury (ali) or acute respiratory distress syndrome (ards), which are common pulmonary diseases in humans, especially in patients undergoing surgery [14]. Studies have confirmed that lipopolysaccharide (lps) plays important roles in the d... |
Recent estimates showed that cancer incidence will almost triple by 2030, with 2026 million new cancer diagnoses and 1317 million deaths . More than 70% of all cancer deaths occurred in low and middle - income countries [1, 3]. Of all types of cancers, breast cancer is the most common cancer among women both in develop... |
The gate control theory of pain developed by melzack and wall in 1965 proposes that tiny neural networks distributed along the dorsal horn of the spinal cord are responsible for relieving the pain in a specific body location when an intense tactile stimulation is applied at the same place . We experience this phenomeno... |
Traditional methods, which offer an individual facility a single rate for all patients, have been widely criticized for making the heaviest care patients economically unattractive . Rapid rises in nursing home costs, coupled with demographic shifts that will further increase the demand for long - term care, making nurs... |
Case - patients undergo a smear examination of the characteristic patch of thick gray membrane and samples are cultured for c. diphtheriae . To describe the epidemiology of diphtheria, we included cases defined as an acute febrile infection with gray - white patch in pharynx, tonsils, or fauces among residents of hyder... |
A 28-year - old female presented with a 6 months history of painless, progressive diminution of vision in the left eye . On examination, her best - corrected visual activity was 6/6 in the right eye and hand movement perception in the left eye . The left eye examination showed axial proptosis of 2 mm, with relative aff... |
The aging population of europe and worldwide means that there are increasing numbers of people being affected by health problems who are living with reduced functional efficiency . Thus, it is necessary to understand the problems as well as social, psychological, and medical needs of chronically ill patients in order t... |
Brain tumors are the second most common form of childhood cancer, after acute lymphoblastic leukemia (all). Given 5-year survival rates that approach 90% for children treated for all and 70% for those treated for brain tumors, there are currently a great many survivors of these cancers that suffer from the consequences... |
Despite the wide availability of pharmacological antihypertensive treatment, it is estimated that 1 of 50 patients with newly diagnosed hypertension will develop resistant hypertension, a condition associated with an increased risk for cardiovascular events and chronic renal disease compared with that of nonresistant h... |
Suicidal patients are commonly encountered in psychiatric practice, and attempted suicide and suicidal ideation are often a cause of emergency treatment and psychiatric hospitalization . The most common psychiatric illnesses in the background of suicide are the affective disorder (ad) of unipolar major depression and t... |
The most remarkable development the disability sector went through over the last 1015 years is the shift in paradigm . The shift from a medical model, a defect model, towards a social model of disability is made . For ageing people and their services a similar but less visible shift in thinking took place . Ageing peop... |
Indian studies showed that middle - aged women reported more psychological distress, more medical problems and lower morale than men . Anxiety and depressive disorders therefore in the present study, an attempt has been made to find level and factors affecting depression and anxiety in women aged 4060 years in a north ... |
Advanced periodontal disease is characterized by severe attachment loss, reduction of bony support, and increased tooth mobility, often resulting in pathologic tooth migration and flaring . When the maxillary anterior teeth are seriously involved, severe esthetic problems, including a deficient alveolar ridge and papil... |
Resistance to antimalarial drugs is a major public health problem, which hinders the control of malaria . Widespread p. falciparum resistance to conventional antimalarial medicines such as chloroquine and sulphadoxine - pyrimethamine (sp) led to a change in malaria treatment policy in endemic countries . Acts have beco... |
A 17-year - old south indian female was reported of a complaint of a pain in mandibular molar for three months . She had the asymmetry since the birth, however she was unaware of any progression of the asymmetry . She also reported of absence of both deciduous and permanent teeth in left posterior region of the upper j... |
Pcos is one of the most common endocrine disorders in women of reproductive age with a prevalence of 5%7% [13].pcos is associated with a broad range of adverse sequelae, including hypertension, dyslipidemia, insulin resistance, hyperandrogenaemia, gestational and type 2 diabetes, which ultimately increase the risk of c... |
Alignment of dna sequences from different species provides an effective tool to decode genomic information, based on the assumption that functional sequences tend to evolve at a slower rate than non - functional sequences . The availability of the complete genomic sequences from a variety of species (14) allows to carr... |
The selection of an artificial tooth or restoration with a proper shade has shown to positively influence the patient s aesthetic perception and improved prosthesis acceptance.3 it is advisable to select the tooth color in harmony with surrounding environment like facial skin, hair, and eye color.4 the tooth shade sele... |
Severe renal dysfunction, in particular, which requires dialysis, has been identified as a risk factor for adverse outcomes after coronary artery bypass grafting (cabg) [13]. Chronic kidney disease (ckd) that does not require dialysis, which has been defined according to levels of serum creatinine or estimated glomerul... |
These patients had chronic colonization or infection of pathogens, the underlying pathological process can be understood as a vicious circle caused by chronic infection . The two main pathogens isolated have been reported as haemophilus influenzae (mean of 42% and a range of 2970%) and pseudomonas aeruginosa (mean of 1... |
Dna base composition, specifically guanine - cytosine (gc) content, is a bacterial taxonomic marker . For example, actinobacteria have high, whereas clostridia have low gc - containing genomes . In addition, assessing the dinucleotide frequency profile, a genome signature, of a genomic dna sequence is a powerful tool t... |
The skin, most visible and accessible organ of the body, may function as an important diagnostic window to the diseases affecting the internal organs including the renal system . Some of the skin changes like pruritus, xerosis, hyperpigmentation, and acquired perforating dermatosis are said to be present regardless of ... |
The study was reviewed and approved by the institutional review board of the university of pennsylvania . Nhc is a company that provided comprehensive wound care management solutions to local wound care centers across the united states . Nhc developed clinical pathways to guide treatment based on reviews of best practi... |
A 2.5-year - old - male child was brought with a chief complaint of acute onset drooping of the right upper eyelid that persisted without improvement for 5 days . There was a preceding history of fever of 8 days duration followed by a vesicular eruption on the right scalp and forehead extending to the tip of the nose .... |
The velocity of scanning a whole glass slide reaches now in less than one minute with a sufficient number of focus points, and will probably further decrease with the new scanner generation . In addition to its main applications which are research (such as tissue micro arrays (tma), interdisciplinary case discussion as... |
One option to consider in auricular reconstruction, particularly when there has been traumatic loss, is the application of a manufactured auricular prosthesis . Offered a good overview of indications, technique, and difficulties with the use of auricular prostheses . It can also be attached directly to the skin by usin... |
Many factors predisposing people to the development of depression are known, for example: monoamine deficiency in the brain regions responsible for regulation of mood, hyperactivity of the hypothalamic - pituitary - adrenal axis and modifications of the amount or function of brain - derived neurotrophic factor elicited... |
The online version of this article (doi:10.1007/s00330 - 015 - 3849 - 2) contains supplementary material, which is available to authorized users . The canadian national breast cancer screening study (cnbss) is one of eight large - scale randomized controlled trials on mammography screening . Compared to the other studi... |
Interferential current (ifc) therapy is a form of transcutaneous electrical stimulation using medium frequency current, generally at about 4 khz1, 2 . The interaction of 2 slightly different medium - frequency currents generates an amplitude - modulated low - frequency current (0250 hz). Because the khz - region has lo... |
Anterior segment optical coherence tomography (asoct) was used to categorize and provide insights into the etiology of capsular bag distension syndrome (cbds). A prospective review was undertaken of 10 cases who presented with signs of late cbds 511 years after uneventful phacoemulsification with in - the - bag posteri... |
There are various terms of obesity loosely used such as abdominal obesity, abdominal adiposity, body fat percentage, and predictors for obesity . Body mass index (bmi) is the most commonly used parameter to measure abdominal obesity for determining whether someone may be defined as obese, overweight, or normal weight .... |
The nordic countries (denmark, finland, iceland, norway, and sweden) have been collecting health data of high quality and complete coverage in national registers for decades.17 all the nordic countries have public health care systems and it is mandatory for the health care professionals to report to the national regist... |
As more and more intracranial lesions are approached through the endoscopic transnasal route, neurosurgeons nowadays come across a lot of lesions in the sphenoid sinus with or without extension to intracranial cavity . We hereby describe our experience with few of the lesions which were in the sphenoid sinus . Isolated... |
Apoptosis is a physiological cellular process of cell death that is initiated by a wide variety of extrinsic and intrinsic signals and stimuli and hence critical in several disease processes . These signals instructing the cells to undergo apoptosis through the activation of a family of proteins known as caspases . Thi... |
Hyperglycemia is common in critically ill patients, and it has been associated with increased mortality and morbidity in adults and children.13 srinivasan et al4 found that blood glucose level> 150 mg / dl was associated with a 3.5-fold increased risk of mortality . In critically ill adults, a large prospective randomi... |
Elucidation of the mechanisms responsible for protective immunity against tumors is a prerequisite to the development of tumor - specific vaccines and effective immunotherapy for cancer . Because of their ability to be specifically captured by dendritic cells (dcs), enhance antigen presentation, and elicit tumor - spec... |
Hartal is a form of general strike in democratic nations, where a political or social organization leads the people to protest against an unfavorable law or rule by shutting down activities in government offices, companies, schools, and colleges as well as disrupting public and private modes of transportation . The org... |
Naegeli franceschetti jadassohn syndrome (nfjs) is a rare form of ectodermal dysplasia inherited as an autosomal dominant disorder . Nfjs and its closely related allelic disorder, dermatopathia pigmentosa reticularis (dpr), are characterized by the absence of dermatoglyphics, reticulate pattern of skin hyperpigmentatio... |
Chronic hepatitis c (hc) is a major public health concern, with the world health organization reporting that approximately 3% of the world's population suffers from the disease 1 . A wellestablished extrahepatic complication of hc infection is mixed cryoglobulinemic vasculitis type ii, a serious disorder in which cryog... |
We report the unusual outbreak of rvf at a northern latitude and in an extremely arid region (although rvf has been reported in egypt, where the nile river helps spread the disease from the south). The high mortality rates and severe clinical signs observed among dromedary camels indicate that these animals played a ma... |
With more than 15,000 newly diagnosed cases in the us in 2012, cll is the most common leukemia in the western world and affects mainly elderly patients . Different manifestation patterns and a wide range of genetic variations like hypermutation of the immunoglobulin heavy - chain genes (ighv), genomic aberrations, and ... |
Bacterial toxins of the cholesterol - dependent cytolsysin (cdc) superfamily form pores in lipid bilayers through the oligomerization of their membrane attack complex / perforin fold (macpf) domain . Cdcs are produced by over five different genera of gram - positive bacteria, resulting in a wide range of animal and hum... |
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