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Pressure ulcers are defined by the department of health as lesions caused by unrelieved pressure resulting in damage to the underlying tissue . They usually occur over bony prominences and are classified by the degree of tissue damage observed . Pressure, shear, friction, moisture, and poor nutrition contribute directl... |
Colorectal cancer (crc) with invasion limited to the lamina propria (lp) is defined as intramucosal carcinoma . The current consensus is that intramucosal crc should not metastasize because colonic lp lacks lymphatics . Tis in the tumor, node, metastasis (tnm) staging system, and endoscopic resection is regarded as ade... |
Liver infarction with portal vein thrombosis (pvt) is a very rare complication of pancreatic inflammatory disease because of peculiarities in its vascular architecture, such as its intrahepatic double blood supply system . Acrodermatitis enteropathica is also an unusual disorder characterized by alopecia, oral and peri... |
The overall incidence of cancer was reported to be 210.5 per 100,000 in 1999 (1). The increases in the rates of each cancer are variable, and the top - ranking cancers in the 1990s and the 2000s are different . For example, the incidences of thyroid cancer and colon cancer has increased dramatically, while the incidenc... |
Calcium channel blockers (ccb) are leading cause of cardiovascular drug overdose and are responsible for 48% of deaths related to cardiovascular drug exposure . Amlodipine is a dihydropyridine group of ccb having half life of 30 - 50 hours and a large volume of distribution (21l / kg). Hemofiltration and dialysis may n... |
The iii brazilian consensus on rhinitis (2012) defines allergic rhinitis as an nasal mucosa inflammation, mediated by immunoglobulin e, after exposure to allergens.1 according to aria (allergic rhinitis and its impact on asthma) initiative recommendation, allergic rhinitis can be classified considering the duration (in... |
Cyclosporine is one of the most common immunosuppressants used in allogenic stem cells transplant (asct) both in children and adults [1, 2]. This population had more digestive problems compared to solid transplant patient; consisting of mucositis and diffuse inflammation of the intestinal tract related to the preparati... |
Atomistic molecular dynamics (md) simulations are useful computational methods in the study of biological systems . However, many phenomena, such as vesicle fusion, protein folding, and peptide aggregation occur at time scales much longer than those currently accessible using atomistic simulation and in some cases do n... |
Neurofibromatosis type 1 (nf1) is an autosomal dominant disorder with an approximate incidence ranging from 1/2,500 to 1/3,000 and a prevalence ranging from 1/2,000 to 1/5,000 in the united states and united kingdom . Patients with nf1 have various manifestations, such as caf au lait spots, neurofibromas, intertriginou... |
Lipid - lowering treatment with statins clearly reduces morbidity and mortality of patients with documented cad [1 - 3]. However, because these trial protocols excluded patients with chronic heart failure, information on the effect of statins in this clinical condition is incomplete . Since the prevalent etiology of he... |
In the japanese classification, gastric carcinoma is generally divided into two pathological types, the differentiated type and the undifferentiated type, according to the presence of histological tubular structures 1; these two pathological types correspond closely to the intestinal type and diffuse type of gastric ca... |
Bacterial leakage and root fractures are the two most important causes for root canal treatment failure . Gutta - percha and resin sealer ah26 are commonly used for canal obturation, but they have drawbacks due to their lack of adhesion to the canal walls . In fact, the root is not strengthened owing to the lack of che... |
Several species of the protozoan parasites belonging to the genus leishmania are the causative agent of a spectrum of zoonotic disease collectively called leishmaniasis . The disease is considered endemic in over 80 countries and about 2 million new cases occur every year, of which approximately 50% of these new cases ... |
Apoptosis is an evolutionarily conserved process in multicellular organisms for eliminating unwanted or damaged cells, and is critical for normal development and tissue homeostasis . Environmental factors, such as uv irradiation or oxidative stress, can cause or increase susceptibility to apopotsis . A number of endoge... |
The systolic blood pressure of the brachial artery of both arms and the posterior tibial artery of both ankles were measured using a blood pressure cuff and a parks model 841-a pocket doppler probe (parks medical electronics, aloha, or). The ratio of ankle to arm systolic blood pressure was calculated for each leg, and... |
Hepatitis b virus (hbv) infection, the major cause of liver cirrhosis and hepatocellulcar carcinoma (hcc), is a serious global health concern . The world health organization (who) reported that approximately 45% of the population lives in an area with a high prevalence of chronic hepatitis b (chb).1 chb is particularly... |
Although a thyroglossal duct cyst is a congenital anomaly and most commonly presents in a pediatric age group, it can also appear in adults . Recent studies have shown that thyroglossal duct remnants are far more common than thyroglossal duct cysts . The key factors involved in the pathogenesis of an acquired cystic fo... |
Hypertension is the leading cause of cardiovascular disease worldwide,1,2 and is the major cause of death and second leading cause of disability after childhood malnutrition globally.3 briganti et al reported that almost one third of australian adults may have hypertension.4 in sub - saharan africa, hypertension is the... |
In the early years of the wars in afghanistan (operation enduring freedom, oef) and iraq (operation iraqi freedom, oif), there appeared to be an increase in the numbers of causalities sustaining a traumatic brain injury (tbi). By early 2005 tbi was being called the signature wound of war in iraq as cases of soldiers su... |
The world health organization (who) ranks indoor air pollution (from biomass fuel combustion) and urban outdoor air pollution 10th and 14th, respectively, among 19 leading risk factors for global mortality . There is indisputable epidemiologic evidence that air pollution exposure in humans increases not only the risk o... |
The prevalence of obesity is increasing worldwide, accompanied by a high incidence of type 2 diabetes (t2 dm) and cardiovascular disease (cvd). Although there is convincing evidence that obesity is accompanied by unfavorable metabolic profiles, such as impaired glucose tolerance, dyslipidemia, elevated blood pressure, ... |
Equine piroplasmosis (ep) is endemic, prevalent and a parasitic disease of all equids, caused by theileria equi and/or babesia caballi that are distributed in most parts of the world (1). The cause of equine theileriosis is a blood protozoan t. equi (laveran 1901). The majority of infected animals showing no clinical s... |
Myopia has emerged as a worldwide public health issue because of its dramatically increased prevalence during the past few decades, especially in east asia [25], with 6090% youngsters affected . Myopia occurs at a relatively young age and is more likely to progress to high myopia . In turn, high myopia is associated wi... |
Tumor necrosis factor (tnf) plays a central role in the pathogenesis of inflammatory bowel disease (ibd), and the introduction of tnf inhibitors has substantially broadened the therapeutic options in ibd . Available monoclonal antibodies which are effective for the treatment of crohn's disease (cd) and ulcerative colit... |
Infection is the most common and most serious complication of major burn injuries and is related to burn size and severity of the injury . Currently, sepsis accounts for 5060% of deaths in burn patients despite major improvements in antimicrobial therapies . Microbial colonization of the open burn wounds is usually est... |
Interventional cardiology has grown rapidly following the development of drug - eluting stents (dess). Des make percutaneous coronary interventions (pci) simpler, longer lasting and safer . With the advent of these devices, interventions for cases of complex coronary anatomy one of the problems is loss of a particular ... |
Deep vein thrombosis (dvt) is a condition involving the formation of a thrombus within a deep vein [1 - 6]. Dvt affects approximately 160 per 100,000 people annually, with relative yearly cost exceeding one billion dollars . The incidence of pulmonary embolus (pe) in patients with dvt ranges from 5% to 20%, and it can ... |
Traumatic posterior hip dislocation with ipsilateral intertrochanteric femur fracture is rare . To the best of our knowledge, this is the first case reporting the concomitant presence of posterior dislocation hip, ipsilateral intertrochanteric- and proximal tibia- fracture with popliteal artery injury . A handful of ca... |
Samples: common minke whales, bryde s whales, sei whales (b. borealis) and sperm whales (physeter macrocephalus) were captured legally under the japanese whale research program in the western north pacific (jarpn) during 19941999, and in the offshore (20002010) and the coastal (20062010) components of jarpn ii . Antarc... |
The obesity epidemic that has been described by the world health organization (who) is more prevalent in women than in men . Despite this greater proneness of women to accumulate body fat when exposed to an obesogenic environment, women are less affected by obesity comorbidities because of difference in fat distributio... |
Uropathogenic escherichia coli (upec), a subset of the extraintestinal pathogenic e. coli (expec), is the principal etiological agent of community onset urinary tract infection (uti) accounting for substantial morbidity and medical costs worldwide . Recent studies have shown that expec isolates have increasingly become... |
A 75-year - old caucasian female with a past medical history of type 2 diabetes presented with fatigue, jaundice, and pruritus for 7 days . Ten days prior to presentation, she had a urinary tract infection that was treated with oral clindamycin, 450 mg every 6 h. her symptoms started 3 days after she started taking cli... |
An accurate determination of the natural history of a cerebral aneurysm has implications on management . Few risk factors other than female gender and cigarette smoking have been identified to be associated with cerebral aneurysm progression, particularly rapid progression . This case series and literature review serve... |
Currently, more than 70% of kidney cancer is diagnosed in the organ - limited form . This percentage increased significantly in recent years mainly due to the wide introduction of imaging techniques . In 2011 in poland kidney cancer was diagnosed in more than 2,700 men and 1,800 women and died from the disease 1500 men... |
Congenital absence of the pericardium (cap) is a rare cardiac condition usually identified incidentally on autopsies and surgical procedures . The prevalence, including cases with other cardiopulmonary anomalies, is approximately 0.002 - 0.004% of the surgical and pathological series . The pathogenesis is multifactoria... |
Vitamin a exists in three physiologically active forms (vitamers) namely retinol (alcohol), retinal (aldehyde) and retinoic acid (acid), which are collectively known as retinoids (which also include synthetic compounds having some biological activity of vitamin a). Vitamin a is an important fat - soluble micronutrient ... |
One - third of adult americans are overweight, defined as a body mass index (bmi) between 25 and 30 kg m, and an additional one - third are obese, defined as a bmi of 30 kg m or greater . There are promising data from the centers for disease control and prevention to suggest that the prevalence of overweight and obesit... |
Numbers were maintained at about this level for a further five years since when there has been a consistent reduction in the mule population . In 2009 the numbers of mules in the country were at their lowest recorded, the actual number being about 51,500 . The reason for mules maintaining their numbers for a longer per... |
Chronic obstructive pulmonary disease (copd) is a respiratory disease characterized by the progressive development of airflow limitation in the lungs, causing primarily shortness of breath (dyspnea) and diminishing physical exertion capabilities [1, 2]. Symptomatic patients with copd are dyspnoeic even when they perfor... |
Overweight and obesity are important clinical and public health burdens worldwide affecting more than 30% of adult population . Aging- and menopause - induced estrogen deficiency results in an increase in body weight or abdominal fat and a decrease in lean mass which contribute to an elevated risk of cardiovascular dis... |
The largest concentration of thalassemia patients are seen in south east asia, sri lanka, bangladesh, north west india, pakistan, middle east countries, greece, and italy . In south east asia, there are 40 million carriers of thalassemia gene, 50% of which are in india alone . The mean prevalence of the carrier status ... |
Data on one or more of the renal function measures at the age of 6064 years (egfr calculated using cystatin c alone (egfrcys), egfr calculated using cystatin c in combination with creatinine (egfrcr - cys), and urine albumin creatinine ratio (uacr)) were available for 2198 study members; birth weight data were also ava... |
Cardiovascular disease (cvd) is the leading cause of hospitalization and death in chronic kidney disease (ckd) patients at all stages.1 the process of cvd is thought to commence early in ckd because it is common in patients commencing renal replacement therapy (rrt).2 foley et al . Found that only 15% of end - stage re... |
Tumour necrosis factor alpha (tnf-) is a pleiotropic cytokine known to play a major role in host defense mechanisms, initiating a beneficial local inflammation which in excess, however, may cause tissue damage . Since 1999, anti - tnf- therapy has been used with success in the treatment of patients suffering from rheum... |
Central retinal artery occlusion (crao) is the occlusion of the central retinal artery resulting in infarction of the retina and acute, painless vision loss . Furthermore, atherosclerosis - related thrombus, embolism, vasospasm, and giant cell arteritis have been known as causes of crao . Since the disease is analogous... |
Hepatitis c virus (hcv) infection has been associated with various extrahepatic manifestations, and diabetes mellitus is one of these . Diabetes in patients with chronic hepatitis c infection (chc) has unique and complex pathogenesis, which distinguishes this metabolic disorder from type 2 diabetes mellitus . In this r... |
One such system is nucleotide excision repair (ner), which eliminates photoproducts from dna strands by dual incision on both sides of a damaged base . When a replicative dna polymerase stalls upon encountering a residual photoproduct on the template strand, it is relieved by other low - processivity polymerase(s), whi... |
The techniques of performing laparoscopic assisted vaginal hysterectomy (lavh), laparoscopic hysterectomy and laparoscopic supracervical hysterectomy are well established in the literature .. these methods have utilized laparoscopes greater than 5 mm in diameter, usually 10 mm or larger . When this surgery is accomplis... |
Intestinal pseudo - obstruction (ipo) is characterized by ineffective intestinal propulsion without mechanical or obstructive factors . Its clinical manifestations include nausea, vomiting, dysphagia, abdominal distension, abdominal pain, constipation, and weight loss . It is also characterized by sluggish or no audibl... |
Pulmonary complications have been shown to be a major cause of morbidity and mortality in the perioperative period, in both cardiothoracic surgical populations, and non - cardiothoracic surgery . Several large studies that have looked at perioperative pulmonary complications (pcc) include a 2000 prospective cohort stud... |
The selection and arrangement of maxillary anterior teeth for edentulous patients in a natural and esthetically pleasing form has remained an elusive and challenging endeavour . Dentist use various techniques, their clinical expertise and aesthetic sense to attain acceptable results . The pre - extraction records can b... |
Aftereffects are a powerful behavioral paradigm used to infer how information is represented in the brain and how neural populations and circuits change over time neural dynamics . In the case of motion aftereffect paradigms, for example, an observer stares at visual motion such as a drifting grating (the adapting stim... |
Limb - saving surgery of bone tumours has increased due to improvement in imaging, adjuvant chemotherapy and radiotherapy . Large massive cortical allografts, large endoprostheses or a combination of both (composite) are the state of the art for reconstruction . Allograft fixation can be achieved with internal fixation... |
Castleman's disease (cd) is a relatively uncommon benign disease that is characterized by lymphoid hyperplasia . We describe herein a case of cd presenting as a soft - tissue tumor in the arm and discuss with reference to the literature . We studied aspirates in which the cytology was indicative of cd and which was sub... |
Engage: european network for genetic and genomic epidemiology; helex: centre for health, law and emerging technologies; hugo: human genome organization; pg: public population project in genomics . Bmk wrote the first draft of the manuscript; jrh, amt, ibl, jk, md and mhz contributed equally to the manuscript . This pro... |
One of the great challenges in chemistry, and particularly electrochemistry, is the catalysis of multielectron or multihole reactions . The mechanism of such reactions is generally ambiguous, particularly whether the reaction consists of a succession of independent oxidation / reduction steps or a concerted mechanism .... |
The international cerebral palsy workshop defined cerebral palsy as a clinical syndrome in which non - progressive disturbances occurring in the brain of the fetus or infant induce activity limitations by causing a permanent disorder in the development of movement and posture1 . Clinicians and researchers categorize ce... |
Fine needle aspiration (fna) of salivary gland represents one of the most challenging areas of cytopathology due to a wide variety of reactive and neoplastic lesions . Pathologically, salivary gland tumors have been described as one of the most heterogeneous groups of human tumors . There is marked cytomorphologic dive... |
However the prognosis of gist has been changed dramatically after the introduction of imatinib mesylate (glivec, previously called sti571). Imatinib inhibits not only bcr - abl tyrosine kinase and platelet - derive growth factor (pdgf), but also c - kit kinase which is constitutively activated in gists . By this reason... |
Until recently the antithrombotic therapies available to patients for the prevention of stroke due to atrial fibrillation (paf) have been fairly limited and have included: warfarin, an oral anticoagulant (oac); acetylsalicylic acid (asa), an antiplatelet agent; or no treatment . Accordingly, the acc / aha / esc 2006 gu... |
The development of weapon ammunition and energetic materials requires higher integrate performance including powerful efficacy, controllable energy release, insensitivity, and being friendly to environment . High energy density materials (hedm) offer the needful properties mentioned above fortunately, with additional a... |
Wounds, especially chronic ones, are now a major health concern affecting a large number of patients and causing a considerable reduction in their health - related quality of life [1, 2]. For this reason, research on wound healing agents is currently an attractive and developing field in biomedical sciences [2, 3]. One... |
Sweat gland carcinomas are rare malignant tumors of the skin.15 one entity is the aggressive digital papillary adenocarcinoma . These tumors are capable of aggressive local invasion resulting in a high recurrence rate, and are characterized by predominantly digital location . As the tumor is slow - growing, painless, a... |
The complex embryologic morphogenesis of the pancreatic gland by fusion of the dorsal and ventral bud of the primordial foregut possibly results in congenital anomalies that remain asymptomatic and are found incidentally during clinical imaging . Other variants of pancreas and pancreatic ducts may cause recurrent pancr... |
Ischaemic or ischemic heart disease (ihd), or myocardial ischaemia, is a disease characterized by ischaemia (reduced blood supply) of the heart muscle, usually due to coronary artery disease (atherosclerosis of the coronary arteries). Its risk increases with age, smoking, hypercholesterolaemia (high cholesterol levels)... |
A 62-year - old man reported with a history of bilateral progressive, painless blurring of vision for the last 2 years . Two years ago, admittedly for visual problems, he underwent uneventful cataract surgery with intraocular lens implantation in the right eye, but with no visual benefit . He continued to experience di... |
Neck pain is a common musculoskeletal disorder, and its economic cost is increasing in modern society . Many people work for a long time on monotonous tasks and consequently suffer from chronic neck pain . The life and work of the worker is usually affected, which leads to a tremendous economic burden due to healthcare... |
Dna sample: a total of 658 dna samples extracted from cattle blood from cebu, iloilo, negros oriental, negros occidental, cavite and batangas in the philippines [33, 34] were used (fig . 1.the philippine map indicating the sampling area (shaded).). In brief, the dna extraction was performed using a qiaamp dna blood min... |
The study of protein aggregation is critically important for understanding the etiology of many misfolded protein disorders such as alzheimer s disease, parkinson s disease, type 2 diabetes, and sickle cell anemia . In addition to a deeper understanding of these conditions, lessons learned from protein aggregation stud... |
In the primary care setting, assessment of growth and development is the foundation of pediatric care, and various forms of neglect and abuse may have an adverse influence on these factors . If the onset is during infancy, such the condition is referred to as failure to thrive (ftt), which indicates both a deficit in t... |
Septic cavernous sinus thrombosis (cst) is a rare condition that can result in high mortality and morbidity rates if not treated immediately . Less common primary sites of infection include the tonsils, soft palate, middle ear, and orbit . Reported cases of middle ear infection the present study is a case report of acu... |
Millions of urban poor women lack access to adequate water and sanitation even though this is considered a basic human right . The health of women often correlates with the health of children and the health of communities more generally, since many women living in urban informal settlements disproportionately support e... |
The study cohort has been described in more detail previously (14). Within a well - defined source population, we manually examined 250,000 births records from 1925 through 1949 and identified an exposed cohort by identifying all newborn infants with a gestational duration <35 weeks and/or a birth weight <2,000 g for g... |
The obesity epidemic is an ongoing and increasing problem in western societies, with a current prevalence of more than 35% in the united states (1). In 2008, annual health costs attributed to obesity exceeded 140 billion usd (2). Excessive overweight is associated with an increased risk of numerous diseases including c... |
Epithelioid hemangioma (eh) was described originally in 1969 as angiolymphoid hyperplasia with eosinophilia (alhe). Lesions usually present as single or multiple red - brown papules or subcutaneous nodules with a predilection for the head and neck region . Involvement of the trunk is extremely rare and only nine cases ... |
Of these, 62 formalin - fixed and paraffin - embedded tissue tumor blocks were selected . The selection was based on the availability of adequate neoplastic tissue within the paraffin blocks . Original diagnoses were based on morphological evaluation in the primary centers and confirmed by three expert pathologists . A... |
Excessive internet use leading to psychological, social, and occupational problems is varyingly termed as piu, internet addiction disorder, and internet dependence (spada, 2014; young, 1998). Multiple cross - sectional studies show that subjects who have so - called internet addiction also frequently have disorders lik... |
Cervical spondylotic myelopathy (csm) occurs due to degenerative changes in the cervical spine leading to progressive spinal cord compression and dysfunction . Cervical fixation along with spinal cord decompression is the most commonly performed surgical procedure for medically intractable patients . As there is concer... |
Mechanism - based pk / pd models typically describe first - order physiological processes that require systems of ordinary differential equations . Repeatedly solving these complex systems of ordinary differential equations during the iterative estimation of random and fixed effects can be very computationally intensiv... |
The bmi is wrongly considered a satisfactory predictor of the percentage of body fat, and it is known that it shows a curvilinear and not a linear association with the body fat percentage in both men and women . Beyond the criticisms recently leveled towards the normalization of weight by the square of the height (norm... |
Tissue collection and msi analysis were conducted as previously described.12 formalin - fixed, paraffin - embedded (ffpe) tissues of 168 msi - h crc cases were retrieved from the pathology archives of our hospitals . All tissue samples originated from patients who received curative surgery for crc between 2004 and 2007... |
Asthma is a chronic immunological disorder characterized by inflammation of airways leading to obstruction, coughing, and wheezing in response to an allergen or inorganic pollutants . Inflammation in asthma occurs due to excessive infiltration of cells predominantly t cells, eosinophils, neutrophils, macrophages, and m... |
Metagenomics is the study of genetic material retrieved directly from environmental samples including the gut, soil, and water . Typically, human gut microbiota behaves like a multicellular organ, which consists of nearly 200 prevalent bacterial species and approximately 1000 uncommon species . Several factors, such as... |
In their lifetimes, without accounting for special cases of major incidents, most people will experience a traumatic event that threatens their life or to cause physical harm . Among the general population of the us, 5090% will experience some form of traumatic event at least once in their lifetimes1 . Post - traumatic... |
Vascular involvement is rarely seen in nf-1 patients with an incidence of just 3.6%, involving mainly larger blood vessels such as the subclavian artery . We report a case of a massive left sided neck swelling caused by the rupture of an aneurysm from the left costocervical branch . An extensive cervical haematoma was ... |
Holmium laser enucleation of the prostate (holep) allows a safe and effective treatment for bladder outlet obstruction (boo) due to benign prostatic hyperplasia (bph). Comparison with conventional treatment modalities shows excellent hemostatic properties and less electrolyte deterioration [2 - 4]. The effectiveness of... |
Biliary obstruction from malignancy of the hepatobiliary system requires biliary drainage through a percutaneous or endoscopic approach . Percutaneous transhepatic biliary drainage (ptbd) has been widely used for a long time, but recently endoscopic biliary drainage has been preferred as a primary method because of var... |
The technique of sentinel node biopsy with lymphatic mapping has revolutionized breast cancer surgery, reducing the resultant risks of undesired consequences from more extensive axillary surgery and leading to the detection of increasingly smaller metastatic foci in the axilla . Surgeons strive to achieve a singular su... |
Drosophila embryonic s2 cells were grown at 25c in serum - free insect culture medium (hyq sfx; hyclone). Primer sequences: cg3436-f 5-atc gct aac agc cat gtc gg-3, cg3436-r 5-ctt acc gat tca agg agc gc-3; grim - f 5-ttc ccg agt ctc tca ccg c-3, grim - r 5-aca gga acc cac acc act gac-3; abdapr - f 5-ttg agt cag gga gtg... |
Yeast strains the strains used in this study are listed in table 1 . Yeast strains were grown in either ypd medium (2% peptone, 1% yeast extract, 2% glucose) or minimal medium (0.67% yeast nitrogen base, 2% glucose, appropriate supplements) at temperatures required for individual experiments (17, 24, 30, or 37 c). Anal... |
Andrographis paniculata (burm . F.) nees (acanthaceae) is a traditional herb that has been used in taiwan, china, india, and other southeast asian countries for treating inflammation - related diseases such as rheumatoid arthritis and viral infections . Andrographolide is a labdane diterpenoid and is the well described... |
As an executive function (ef), working memory refers to the brain system that stores and manipulates information over brief periods and represents a key process for cognitive functions such as planning, reasoning, and problem solving . The reading span test (rst) was developed and implemented to behaviorally measure in... |
A 6-year - old boy was admitted for cardiac murmur and a tingling sensation of the lower extremities on exercise . Physical examination revealed normal pulses in all four extremities with a blood pressure of 130/60 mmhg in the right arm, 132/70 mmhg in the left arm, and 100/74 mmhg in the lower extremities on admission... |
Patients with inflammatory bowel disease (ibd) have underlying immune dysregulation; they also frequently require exogenous immunosuppressive agents of different types both as induction and maintenance therapies for their disease state . As a consequence, most patients with ibd are at increased risk of developing sever... |
Thyroid nodules showing follicular morphologic features include adenomatous nodule, follicular adenoma (fa), follicular carcinoma (fc), and follicular variant of papillary thyroid carcinoma (fvptc). Cytologic features are known to overlap among these tumors [2, 3], and definite diagnosis of fa, fc, and fvptc is mostly ... |
We previously reported that in women the proportion of intertrochanteric fractures rises with age, while in men it is the proportion of subcapital fractures that rises.1 this was found in a study of 2,150 hip fracture patients in london, ontario (population approximately 350,000), over a five - year period, which was c... |
The numbers of eosinophils and basophils were found to be increased in tissue, blood, and bone marrow and also correlated with disease severity [13]. Additionally, several studies showed that eosinophil / basophil progenitor cells, which develop from bone marrow cd34 cells under the influence of specific chemokines and... |
Molecular docking is a computational method that predicts how a ligand interacts with a receptor . Hence, it is an important tool in studying receptor - ligand interactions and plays an essential role in drug design . Particularly, molecular docking has been used as an effective virtual screening tool and successfully ... |
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