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Guanidinoacetic acid (gaa) occurs naturally in the human body and acts as a precursor of creatine, the latter playing an important role as an energy carrier / mediator in the cell 1, 2 . Gaa itself along with l - ornithine is formed in an enzyme - catalyzed step from l - arginine and glycine, mainly in the kidney and p... |
Risk - taking behaviors that can have lifelong implications are often begun in adolescence and young adulthood . Two common health - risk behaviors that are frequently initiated are cigarette smoking and the alcohol consumption . The long - term negative health consequences of these behaviors have been well documented,... |
Recent epidemics of mosquito - borne viral infections in countries neighboring iran i.e. Dengue, chikungunya and west nile infections in pakistan, dengue and rift valley fever in saudi arabia, and west nile infection in iraq (1, 2, 3) have placed this country at a serious risk for mosquito - borne diseases . Our interc... |
Outbred hairless mice (mus musculus, skh-1 strain), originally purchased from charles river deutschland (sulzfeld, germany), were bred and maintained in the laboratory . The strain of b. afzelii originated from a naturally infected nymphal i. ricinus tick collected from vegetation in suburban berlin (9). We have previo... |
Study area - the study was conducted in the cidade nova neighbourhood of manaus (307 s 5957w) (fig . Manaus and cidade nova had estimated populations of 1,802,014 and 121,135 in 2010 (ibge 2010). The houses of the mainly residential neighbourhood are made of wood or brick, usually with verandas and/or backyards . The m... |
Acute respiratory failure (arf) is the most common organ failure in a general intensive care unit (icu), and the mortality rate is high . In a recent epidemiological study conducted in scandinavia, the 90-day mortality rate in arf patients was similar to those in acute respiratory distress syndrome (ards) and acute lun... |
In the last decade, it has been increasingly recognized that global hiv / aids efforts often fail to address the reproductive health and specifically family planning (fp)needs of people living with hiv . The need for an integrated approach to reproductive health and hiv was formally acknowledged as early as the 1994 in... |
Diarrheal diseases are a great public health problem that leads to morbidity and mortality of infants and children particularly in developing countries and even in developed countries . In developing countries recent conservative estimates have indicated that 702,000 children die each year from rotavirus disease and th... |
Porous tantalum is a relatively new biomaterial in orthopedics, used in domains such as hip and knee arthroplasty, hip osteonecrosis surgery, and spine surgery.1 it consists of a carbon scaffold on which pure tantalum is deposited.23 porous tantalum possesses some unique mechanical properties,46 mainly due to its high ... |
Warfarin, the most commonly used anticoagulant in north america, is a vitamin k antagonist that is demonstrated to be efficacious in the prevention of thrombosis and thromboembolism . Its use dates back to the 1950s, when it was approved as an anticoagulant in the united states.1 current indications for its use include... |
Previous studies (15) suggest that 1520% of new prescriptions for medications treating elevated levels of glucose, blood pressure (bp), or lipids are never filled and that only 60% of those who fill a newly prescribed medication in these classes have persisted in taking the medication 12 months later . However, medicat... |
Epilepsy is characterized by spontaneous recurrent seizures and comprises a diverse group of syndromes with different aetiologies . Epilepsy is the second most common brain disorder, affecting about 1% of the world's population . Temporal lobe epilepsy (tle) remains as one of the most severe and frequent pharmacoresist... |
Low back pain is a very frequent symptom at general orthopaedic consultation, and establishes a long term chronic illness between 2% and 7% of times . Although, a great majority of the chronic low back pain is related to vertebral degenerative pathology, other possible reasons, even unusual, have to been considered lik... |
Endometriosis, a common polygenic / multifactorial disease, might be caused by an interaction between multiple genes as well as the environment 1 . Endometriosis displays features similar to malignancy, including local invasion and aggressive spread to distant organs . Tumor suppressor genes play a role in the regulati... |
To describe a visually evoked potential (vep) examination performed on a patient with a keratoprosthesis . We report the case of a 60-year - old patient with a fyodorov - zuev keratoprosthesis in the right eye complained of gradual visual deterioration in that eye . His past medical history consisted of failed corneal ... |
The birth of a child is a major life event that can be filled with excitement, anticipation, and joy . However, the transition and adaptation to new demands, roles, responsibilities, and changes in relationships can be stressful, especially for first - time mothers . In addition, new mothers typically encounter physiol... |
Most tumors in lower female genital area are originated from vaginal or urethral mucosa (1, 2). Mostly, they are accompanied by apparent symptoms, such as vaginal bleeding or hematuria, which lead to an easy detection of the tumor (2). However, the mass developed at urethrovaginal septum without definite involvement of... |
Hyperkalemia is a serious medical condition that can cause muscle weakness, paralysis, and cardiac arrhythmias and is associated with increased mortality.13 defined as serum potassium greater than 5 meq / l (5 mmol / l), hyperkalemia is rare in the general population because the renal system tightly regulates potassium... |
Peritoneal metastases from lung cancer are a rare event . In this paper, we report the case of a patient with adenocarcinoma of the lungs who had isolated peritoneal metastases at the time of diagnosis . We report a 55-year - old female who presented with shortness of breath, decreased effort tolerance, cough, and weig... |
Different jaw regions exhibit different bone densities, which might be under the influence of various factors, including osteoporosis . Osteoporosis is the most common metabolic bone disorder, which is characterized by a decrease in bone mineral density (bmd) or changes in the bone microstructure . Bmd is a medical ter... |
A 66-year - old woman with recently diagnosed durie and salmon stage iiib igg kappa myeloma was started on cybord chemotherapy including cyclophosphamide 500 mg orally weekly, bortezomib (given weekly after hemodialysis, at a dose of 2.5 mg subcutaneously), and dexamethasone 2040 mg orally weekly, having failed plasmap... |
Acute exacerbations of chronic obstructive pulmonary disease (copd) account for a considerable number of acute medical admissions, with the majority being admitted through the emergency department (ed). There were 10,863 admissions in ireland for copd in 2010, which account for 2.3% of all hospital inpatients, excludin... |
A detailed understanding of the anterior cruciate ligament (acl) is the basis for anatomical acl reconstruction . Many cadaver studies have been performed to evaluate its midsubstance size and shape and its tibial insertion in the fossa of the area intercondylaris anterior . Most authors described the tibial acl insert... |
Autism is a relatively common and heterogeneous neuropsychiatric disorder characterised by reduced social and interindividual contacts and interactions . Complete absence of eye contact and speech can be observed in severe forms of autism . Its incidence is estimated at about 1/1000 to 1/2000 with a biased male - to - ... |
The us health care delivery system is comprised of at least five components: cost, quality, accessibility, maintenance of the medical education system, and availability of a well trained physician workforce, all of which are being threatened by major challenges.1 among these challenges is the high cost of health care, ... |
The aging population in malaysia has significantly increased in number over the last few decades . It is imperative to perform extensive research to provide evidence - based strategies for successful aging.1 aging affects many domains of cognitive performance.2 even though evidence indicates that age - related cognitiv... |
The classical predator - prey model based on the logistic growth principle and hollings predation theory is as follows: (1)dxdt = x(1xk)axy1+chx, dydt = bxy1+chxdy, where x and y represent the density of prey and predator species with carrying capacity k. the constant a denotes the food intake rate of predator, b denot... |
An incidence of 20 - 25% in sexually active and 30 - 35% in all women irrespective of age has been reported . The surgical management of myomas has advanced significantly, there has been a renewed interest in the removal of myoma alone, i.e., myomectomy rather than hysterectomy, which was carried out historically . Wit... |
Viral hepatitis affects millions of people worldwide, with over 20 million people diagnosed with acute infections annually and over 150 million with chronic viral hepatitis (http://www.who.int/mediacentre/factsheets/fs328/en/, http://www.who.int/mediacentre/factsheets/fs204/en/, http://www.who.int/mediacentre/factsheet... |
Terminal deoxynucleotidyl transferase (tdt)-mediated dutp nick end - labeling (tunel) kits were purchased from nanjing keygen biotech co., ltd ., nanjing, china . Anti - puma, anti - caspase-3 primary antibodies and streptavidin - biotin - peroxidase complex (sabc) immunohistological staining kits (sa1022) were purchas... |
Flies are pests of great medical and veterinary significance and are one of the most important vectors of human diseases worldwide [1, 2]. Houseflies are important nuisance pests of domestic animals and people, as well as the main fly vectors of foodborne and animal pathogens . Due to their indiscriminate movements, ab... |
This disease has been already reported in usa's middle west and northeast; latin america, asia, africa and several cases with no etiological confirmation in europe . Histoplasmosis is the most prevalent mycosis disseminated in central america, united states (ohio and mississippi) and mexico's southeast . Although histo... |
Low bone mineral density (bmd) has long been established as an important risk factor for hip fracture or lumbar fracture . It follows that knowledge of the other factors, such as obesity, smoking, alcohol intake, drugs intake, and long - term bed rest, influencing bmd is crucial for preventing and treating osteoporotic... |
Research examining the link between work - family conflict (wfc: when work and family roles conflict with each other) and alcohol use has generally found the strength of the relationship between these variables to be small (see). This may be due to a general failure to examine individual differences (other than gender ... |
Orofacial clefts, and in particular cleft lip and palate, are major human birth defects with complex etiology . The cleft face has been studied extensively . However, the results reported in literature vary and sometimes are in disagreement . The reason for differences includes different treatment procedures for the sa... |
The pig farm, a closed farrow - to - finish 1-site operation in buenos aires province, had 519 sows . Pig death rate from farrowing to slaughter remained at 9.5% before and after the outbreak . Ten days before the outbreak, the farm manager and his wife reported clinical signs of influenza in themselves . On june 15, 2... |
A distinct population of splenic igmigdcd21cd1 peripheral b lymphocytes known as marginal zone (mz) b cells resides close to the marginal sinus 123456 . Other b cells, including some memory cells, also reside in mzs but can be distinguished from mz b cells . Mz b cells are large lymphocytes, have a distinct morphology ... |
Chronic lymphocytic leukemia (cll) is one of the most common hematologic malignancies, affecting approximately 510 people per 100,000. (1) population - based data indicate that patients with cll are at increased risk for developing second cancers compared to the general population. (25) specific malignancies for which ... |
There are numerous notions relating to mental illness and mental health in manimekalai, the tamil buddhist epic of the post - sangam era of tamil literature . This period is renowned for the publication of the eight anthologies and 10 lyrics and also the 18 didactical works including thirukkural . All these works are t... |
Type 1 diabetes (t1d) remains the predominant form of diabetes in childhood (1,2). An increase in incidence over the past three decades worldwide, with significant geographic variation, has been reported (311), with some studies showing a downward shift in the age at diagnosis (68,12). Registries have demonstrated incr... |
Blood blister - like aneurysms (bbas) have several unique characteristics that differ from those of regular saccular aneurysms . These include 1) a typical small hemispheric, broad - based appearance, with a lack of an identifiable neck originating from a non branching site of an artery1,10,15,16,22); 2) instability, w... |
The prevalence rate of chronic degenerative arthritis is very high . Among elderly persons aged 65 years or more, females are estimated to have two times higher prevalence rates of chronic degenerative arthritis than males, and most elderly persons have degenerative arthritis1 . The physical characteristics of chronic ... |
The importance of being physically active has been well documented from a public health perspective, with increased activity associated with reduced risk for the development of chronic health conditions like cardiovascular disease [14]. Researchers have also reported positive mental health outcomes ranging from improve... |
According to the who classification, undifferentiated carcinoma of the pancreas (udc) is defined as containing large eosinophilic pleomorphic cells and/or ovoid - to - spindle - shaped cells that grow in cohesive formation, and it has a poor prognosis . Undifferentiated carcinoma with osteoclast - like giant cells of t... |
Heavy menstrual bleeding is a significant health problem in premenopausal women and that would be equivalent to menorrhagia (1, 2). The treatment of menorrhagia can either be medical therapy, hysterectomy or destruction of the endometrial . Medical therapy is the first - line therapy, but this is not successful while h... |
Bacteria and their byproducts have key role in the initiation and progression of pulpal and periapical diseases . Root canal morphology is a complex system with ns, anastomoses and lateral or accessory canals which harbor microorganisms . Enterococcus faecalis (e. faecalis) which is a gram - positive, facultative, anae... |
Various predisposing factors include some religious and cultural practices, personal hygiene, smoking, phimosis, inflammatory conditions such as lichen sclerosus or balanoposthitis, ultraviolet radiation, and the presence of human papillomavirus . Squamous - cell carcinoma (scc) is the major histopathological subtype a... |
Epidemic of diabetes mellitus is growing globally, with 90% of all diabetes patients having type 2 diabetes mellitus (t2 dm). T2 the progressive nature of the disease leads to the development of microvascular complications resulting in increased morbidity and health care costs . About 50% of patients suffering from dia... |
Myiasis or infestation with fly larvae is common in domestic and wild mammals around the world, and is caused by different species of flies . Advanced age, poor hygiene, bad housing conditions, vascular disease, and diabetes are the predisposing factors for myiasis . In humans, myiasis is seen more frequently in rural ... |
Approximately 260,000 cases of pulmonary embolism (pe) are clinically diagnosed each year in the united states; and, in the absence of prophylaxis, the incidence of fatal pe ranges from 0.1% - 0.8% in patients undergoing elective general surgical procedures . Since the introduction of laparoscopic cholecystectomy (lc),... |
Many studies indicate that breast cancer health disparities exist among women of different races, ethnicities, socioeconomic statuses, geographic locations and age [1, 2]. According to the centers for disease control and prevention (cdc), national program of cancer registries (npcr) while the age - adjusted incidence r... |
Hypereosinophilia is an abnormal condition defined by the presence of more than 500 eosinophils per microliter of blood . Hypereosinophilia occurs in allergic reactions, helminthic infestation, collagen vascular disease and malignancies etc . (1, 2). The diagnosis of the idiopathic hypereosinophilic syndrome is based o... |
Inherited arrhythmia syndromes may cause sudden cardiac arrest (sca) in patients with a structurally normal heart . Mutations in the voltage gated sodium channel can produce distinct arrhythmogenic syndromes: brugada syndrome (brs), long qt3 syndrome (lqt3) and progressive cardiac conduction disease . Mutations in brs ... |
Thymic cysts account for 1% to 3% of anterior mediastinal masses and can be divided into two types - congenital cysts and acquired cysts . Acquired thymic cysts, unlike congenital cysts, are multilocular and arise as a reactive process secondary to inflammation or malignancy . Multilocular thymic cysts (mtcs) have been... |
Study patients were enrolled from june 11 through 30, 2009, a time that corresponds to the end of autumn and the beginning of winter in the southern hemisphere . Patients seeking care at cemic university hospital and other healthcare providers in buenos aires (federal district) were enrolled if they met the criteria fo... |
Boron nitride nanotubes (bnnts), similar to carbon nanotubes (cnts), have attracted wide attention thanks to their potentially unique and important properties in structural and electronic applications.1,2 a bnnt is a structural analog of a cnt, but, despite this similarity, it presents many different chemical and physi... |
In clinical research, both outcomes and predictors are frequently collected repeatedly over time and complex mediated relationships may be present among the variables of interest . For example, in a study of the relationship between alcohol use and hiv disease progression, heavy alcohol consumption may affect antiretro... |
Over the past 50 years or so, there have been many reports of ab diblock copolymer self - assembly in solvents that are selective for only one block . In principle, varying the relative degrees of polymerization (dp) (and hence volume fractions) of each block enables a wide range of morphologies to be obtained in dilut... |
China is the world s largest cigarette consumer and producer (1). In 2002, about 350 million chinese adults reported having smoked at some point and 300 million reported being smokers at the time (2). Chronic obstructive pulmonary diseases (copd) are a growing health problem and remain a major consumer of health - care... |
The human rad51 protein (hsrad51aaabbreviations: hsrad51, human rad51 protein; ssdna, single - stranded dna; dsdna, double - stranded dna; poly(da), poly(deoxy-1,n6-ethenoadenylic acid); itc, isothermal titration calorimetry .) Is crucial for dna repair processes that are based on homologous recombination between damag... |
Dermatopathic lymphadenitis (dln) is a well - described histopathological entity characterized by the expansion of the subcortical zone by dendritic histocytoid cells due to barrier disruption of dependent skin . Dln is often seen in patients with skin diseases exfoliative or eczematoid inflammatory erythrodermas, espe... |
Alpha-1 antitrypsin deficiency (aat) is a hereditary recessive autosomal disease caused by mutations in the aat gene . This disease is characterized by abnormally low aat concentrations in plasma, which, in its homozygote form, carries a high risk of the development of early pulmonary emphysema and, occasionally, liver... |
The work of teachers has a fundamental social value because education can ensure economic growth, and technical and scientific development in any society . In brazil, there are over 2.6 million teachers working in basic and higher education, and they are responsible for instructing millions of brazilian students1 . The... |
During the past decade, community - associated methicillin - resistant staphylococcus aureus (ca - mrsa) has emerged worldwide . Although there have been some evidences of intercontinental spread of major ca - mrsa clones, most ca - mrsa clones showed the continent - specific distribution (1). Especially, panton - vale... |
Cardiovascular diseases remain the most frequent cause of global death worldwide, and the most common is coronary artery disease, with a mortality rate of 12.8% in 2011 . Acute coronary syndromes significantly contribute to the burden of cardiovascular disease . Reduction of cardiovascular diseases is therefore a key c... |
The article by cuthbertson and colleagues deals with an important topic these days in perioperative anesthesia and intensive care . Numerous clinical studies published in recent years seem to fit together like pieces of a puzzle, with the same overall message: hemodynamic optimization by fluid loading, particularly whe... |
Crick base pairing, while the structural, regulatory, and catalytic functions of rna are achieved by the formation of well - defined 3d structures resulting from a combination of normal watson crick pairs and a wide variety of non - canonical base pairs as well as other tertiary interactions . Base interactions is impo... |
Stds are transmitted from someone to another through sexual activities and close touch (vaginal, rectal and oral). Among the most common stds are chlamydia, gonorrhea, trachoma, herpes, syphilis and hiv . American diseases prevention and control center (2010) reported prevalence of chlamydia, gonorrhea, syphilis (0%wit... |
Brain fingerprinting is a variant of the guilty knowledge or concealed information test (gkt / cit; lykken 1959, 1960). The cit aims to determine the presence or absence of crime - related information in a suspect s memory . It has been used with a variety of dependent measures, most notably with recordings of autonomi... |
Regeneration of periodontal tissue that has been lost as a result of disease is the ultimate objective of periodontal therapy in advanced periodontal breakdown . Periodontal regeneration can be achieved by a variety of non - surgical and surgical therapies . Periodontal surgical debridement and resective osseous surger... |
Study areas and ethics statement - t. cruzi isolates from humans, triatomine bugs and mammalian reservoirs from 19 departments (amazonas, arauca, boyac, bolvar, caquet, caldas, casanare, cesar, cundinamarca, guaina, guajira, huila, magdalena, meta, norte de santander, putumayo, santander, tolima and vaupes) in colombia... |
In 2008, there were 796 million illiterate adults, which represents approximately 17% of the world's adult population.1 the illiteracy rate remains high among the elderly in south korea, especially in rural areas . In yonchon, a korean rural agricultural area, 26.4% of the elderly are reported to be illiterate, and ill... |
Many studies on treadmill walking using a body weight support (bws) device for patients with dysbasia have recently been reported . Werning1 and dietz2 reported its usefulness in improving the walking ability of spinal cord injury patients in 1992 and 1994, respectively, and walking speed - increasing and walking abili... |
The term polyp of the colon refers to a protuberance into the lumen from the normally flat colonic mucosa . Polyps are usually asymptomatic but may ulcerate and bleed, cause abdominal pain, and, when very large, produce intestinal obstruction . They are small nodules or polypoid lesions composed of normal cellular comp... |
Participants were recruited in january 2008 by 48 general practitioners from a cooperation of 14 primary care practices in eindhoven and five surrounding villages . A dutch translation of the finnish diabetes risk score (findrisc) (13) was sent to general practitioner patients aged 40 and 70 years (n = 16,032). All ind... |
Type 2 diabetes mellitus (t2 dm) is one of the fastest growing health problems in the world, reaching epidemic proportion; globally it is estimated that 382 million people suffer from diabetes, that is, a prevalence of 8.3% . T2 dm is the fourth leading cause of death in developed countries, with a twofold excess morta... |
Heroin - induced spongiform leukoencephalopathy (hsle) usually affects young people and is characterized pathologically by vacuolar degeneration as a result of primary damage to myelin . The spongiform vacuolar degeneration is closely associated with the severity of demyelination in the cerebral white matter . Most sur... |
For the past few decades, there has been a growing interest in the modification and application of chitosan in medical and health fields . Chitosan has been the material of choice for the preparation of nanoparticles in various applications due to its biodegradable and nontoxic properties . Chitosan is soluble in acidi... |
Development of patient safety has a major role in preventable disabilities and mortalities in hospitals . Patient safety improvements are being achieved as a result of medical care provided for patients in countries, which have direct impacts on lives saved and preventing patients disabilities . Evidence is gradually e... |
The epidemiologic evidence of the prevalence and consequences of pediatric obesity is well documented . Currently, there is considerable emphasis on establishing effective prevention and treatment protocols for pediatric obesity [2, 3]. In 2007, an expert committee put forth recommendations for the assessment, preventi... |
Central venous catheter (cvc)-related bloodstream infection is associated with significant mortality and morbidity in critically ill patients, much of the focus, however, has remained on the bacterial pathogens . Catheter - associated mycobacteremia is a rare entity, even in oncology patients undergoing chemotherapy vi... |
Catalytic techniques for producing graphene and carbon nanotubes (cnts), particularly those based on chemical vapor deposition (cvd), are widely seen as most promising for achieving the requisite level of control over material structure and quality that is demanded by applications . Key to growth control is a detailed ... |
Social intelligence monitoring in persons with orbitofrontal cortex injury was the subject of a previous article in this journal . The authors reported there impairments in conversations with strangers on intimate topics, that is, unconscious, inappriopriate self - disclosure while answering questions . Such self - dis... |
Prognosis in patients with breast cancer depends mainly on the extent of lymph node involvement, size of the tumor, and the histological grade of the tumor . Among these factors, axillary lymph node status is regarded as the single best marker of prognosis [1, 2]. For axillary nodal involvement, treatment in the form o... |
Dermatological terms may be more than a mouthful; they can be difficult to remember and highly esoteric . An electronic and manual search of standard dermatology texts was done to compile these terms . This article is meant to serve as an interesting aid to dermatology, upon which residents can build their knowledge . ... |
Neck circumference (nc) was recently associated with various cardiovascular risk factors such as insulin resistance and biochemical components of metabolic syndrome such as fasting glucose, fasting triglycerides, and blood pressure, independent of body mass index (bmi) and waist circumference [-]. However, few studies ... |
For all subjects, demographic, anthropometric, biochemical, and anatomical data included in the current study were reported previously (6,7). Briefly, human sural nerve biopsies were obtained during a double - blind, placebo - controlled, 52-week trial of alc . The trial included both type 1 and 2 diabetic patients all... |
One of the challenges that we encountered in extending the linneaus collaboration beyond the confines of countries where primary care was already well established was in developing a mechanism to get engagement from physicians and policymakers to an agenda that explicitly addressed issues related to patient safety . Wo... |
Sepsis was defined as gbs bacteremia in the presence of consistent clinical signs and symptoms . Capsular typing was performed by a multiplex pcr as described (9), and the hypervirulent st-17 clone was detected by real - time pcr, as reported (6). Susceptibility testing, antibiograms, and mics were performed according ... |
Malignant neoplasms arising primarily from the heart and large vessels are rare, and those arising from the pulmonary artery are even rarer . Patients with pulmonary artery tumor are at increased risk of life - threatening events when they become symptomatic . Major artery thromboembolism and acute right heart failure ... |
All data were obtained from the university healthsystem consortium (uhc) (chicago, il) clinical data base / resource manager (cdb), a large administrative database to which uhc principal members submit comprehensive administrative data files . Uhc's principal members include approximately 120 us academic medical center... |
Diabetes mellitus represents a major risk factor for the development of coronary artery disease [1, 2] and an important predictor of outcome in patients undergoing percutaneous coronary intervention (pci) [3, 4]. Recent studies have suggested a potential and independent prognostic role of preprocedural blood glucose le... |
Systemic lupus erythematosus (sle) is a chronic autoimmune disease of unknown origin that affects several organ systems; diverse immunological abnormalities that are associated with this disease have been recognized both in human and in animal models with the most consistent being: (1) loss of b cell tolerance, (2) abn... |
Dehumanization, by which they mean the thing that occurs when a subject, s, perceives people who belong to some cultural outgroup, g, as having a lesser degree of humanity than herself and others she identifies with . Their inquiry is partly motivated by the conjecture which they credit to the psychologist gordon allpo... |
The negative change of muscle mass from maturity to senescence and the corresponding loss of functional capacity are of high clinical significance [1, 2]. The most physiologic means to fight this decline of muscle mass and function is a physically active lifestyle or even better, physical exercise . Indeed, a plethora ... |
Some 4 to 5 billion years ago, the earth formed, and almost as soon as it cooled about 500 million years later, life emerged . For another 2 billion years, the most toxic antagonist to life, oxygen, accumulated in the atmosphere until it reached the levels we face today . Bacteria evolved the trick of harnessing oxygen... |
A term appropriate for gestational age, male baby admitted to our neonatal intensive care unit with vesicular rash with erythematous base on the face on day 5 of life . On the next day, mother had developed vesicular skin eruptions with severe pruritus suggestive of chicken pox 2 days prior to the delivery, which was c... |
Most of the current global clinical practice recommendations, including those of the american diabetes association, the european association for the study of diabetes, and the korean diabetes association, propose that metformin, if there are no contraindications, should be initiated with concurrent lifestyle modificati... |
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