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Early detection and eradication of malignant tumors at an early stage before metastasize and spread to neighboring areas, can be prevented from threats and problems later . During 20032007 almost 0.0%, 0.9%, 6.0%, 15.0%, 20.8%, 19.7%, 22.6% and 15.1% of mortality has occurred in the following order, 20 yr, 2034, 3544, ... |
The estimation of age is an important and is commonly carried in medico legal area . Assessment of age is often required while administering justice to an individual involved in the civil and the criminal litigation . Teeth are known to aid in personal identification and age estimation as they are highly durable and re... |
With heart transplantation comes well - documented medical and psychosocial challenges [1, 2]. Healthcare professionals are dedicated to educating and supporting transplant recipients and their families throughout this potentially difficult trajectory in order to promote engagement in self - management . Recipients are... |
Air - displacement plethysmography (i.e. Bod pod) has gained popularity among body composition researchers since its introduction in 1995 . This is mainly attributable to the non - invasive test - procedure and the lack of technical expertise required compared to the traditional hydrostatic weighing procedure . The bod... |
Past clinical understanding confined the burden of chronic hepatitis c infection (hcv) to later stages of hepatic impairment . Now it is known that hcv's extrahepatic manifestations (ehms) and reduced health - related quality of life (hrqol) often develop before hepatic impairment . Diagnostically, this understanding h... |
Cerebrovascular disorder, mainly including ischemic and hemorrhagic stroke, is the third cause of death after cardiovascular disease and cancer and the leading cause of long - term disability in adults in china . Although stroke mortality has declined in the past decades, its prevalence and morbidity increased dramatic... |
Its main characteristics are deficits in social communication and relationship, verbal communication and language impairments, and repetitive / restrictive behaviors and interests . Some of these children do not like to try new foods and have food selectivity . Children with autism intake vitamin b6 and vitamin e more ... |
I. b., z. m., p. c., l. h., and a. h. are employees of pfizer inc . And hold significant stocks and shares of pfizer inc. |
Rhinitis is the inflammation of the mucous lining of the nose, and it can lead to symptoms including rhinorrhea, nasal obstruction, post - nasal drip, itching, and sneezing . The etiologies of rhinitis include infection, anatomical anomalies, immunological disorders, hormonal imbalance, and ciliary defects [1, 2]. Simi... |
Some patients show signs of wakefulness as demonstrated by eye opening, but are incapable of a meaningful reaction to stimuli . This condition is known as the vegetative state (vs).1 decisions on life - sustaining treatment for patients in the vs have been an issue of intense discussions over the last 40 years . Life -... |
Proteomic profiling based on enzyme activity is assuming significance in drug discovery as it becomes possible to profile selectivity of drugs and their mechanism of action . Such an approach focuses on protein function, an aspect which has been missing from expression proteomics . A functional proteomic profiling appr... |
A substantial proportion of patients who repeatedly present to hospitals with symptoms for which conventional pathology cannot be identified, show evidence of psychological distress that is either not expressed or is unrecognized in the general practice consultation . The phenomena has two aspects: the expression of ps... |
Immunoglobulin a nephropathy (igan) is the most common form of primary glomerulonephritis worldwide, and is associated with a poor prognosis, resulting in end - stage kidney disease in approximately 40% of cases.13 because the poor prognosis of igan is partly a result of delayed diagnosis, strategies for early diagnosi... |
Non-24-hour sleep wake syndrome is a sleep disorder in which the sleep wake cycle exceeds 24 hours, and this occurs not only in blind subjects but also in sighted individuals.1,2 however, this syndrome hardly occurs in sighted individuals;2 the exact mechanism in sighted individuals with non-24-hour sleep some evidence... |
Neuraminidase (na) is one of the two major surface antigens of influenza viruses . The enzymatic activity of na contributes to efficient viral replication as it enables spread in a host by cleavage of new virions from infected cells to permit dispersal of aggregated virions ., neuraminidase may also digest decoy recept... |
The somatosensory amplification scale (ssas) is a 10-item self - report instrument designed to assess a tendency to experience normal somatic and visceral sensations as intense, noxious, and disturbing (1). The concept of somatosensory amplification involves self - examination, increased attention, and vigilance to unp... |
Acute brain injury is a major cause of morbidity and mortality which correlates partly to the initial cerebral insult (1). Following traumatic brain injury (tbi), the function of some organs is impaired, contributing to a worse outcome . Systemic inflammatory response syndrome (sirs) is commonly encountered following a... |
Ischemic heart disease remains a leading cause of morbidity and mortality worldwide.1 borderline coronary artery lesions are responsible for about 80% of acute coronary syndromes (acs).2 it is not uncommon during the performance of coronary angiography to identify borderline coronary stenosis (> 40 and <80%) in the abs... |
A major goal in pediatric dentistry is to maintain primary dentition in an intact state until permanent successors erupt . Primary dentition is essential for maintenance of arch length, mastication, speech and esthetics and prevention of abnormal oral habits . This does not mean that tooth needs removal; it can be reta... |
Malignant pleural mesothelioma (mpm) is a rare malignant neoplasm that typically affects individuals occupationally exposed to asbestos through a variety of industries . Mpm is cancerous proliferation of mesothelial cells that involves a large extent of the pleural cavity and is the most common primary neoplasm of the ... |
While the number of proteins for which the structures are known seems to increase exponentially each year (there are now almost 72,000 structures in the research collaboratory for structural bioinformatics [rcsb] protein data bank), only a handful of intrinsic membrane proteins are among this group, despite the fact th... |
Over 50 million women who live in areas of high malaria transmission become pregnant every year, and thousands of these women die . Women in their first and second pregnancies are at particular risk of infection with plasmodium falciparum, which is a major risk factor for maternal and foetal mortality and is implicated... |
Vaccination programs for immune activation are vital for preventing the spread of infection and decreasing the severity of infection in individual patients.1 vaccines can be administered orally or by inhalation; however, subcutaneous, intradermal, or intramuscular injections are still the most common routes of administ... |
Patients with frequent angina (1 episode per week) report greater physical limitations and decreased quality of life compared with patients with minimal angina.1 the goals of chronic stable angina management are not only to control symptoms, but also to reduce the risk of adverse clinical outcomes.26 as symptom control... |
A number of epidemiological studies carried out around the world have shown that the prevalence of epilepsy rises rapidly above this age, even increasing beyond the other prevalence peak which appears in infancy . On the one hand, we have those patients whose epilepsy started at whatever age and who are now over 60 yea... |
The recently published notice of proposed rulemaking (nprm) for the common rule acknowledges the potential loss of public trust associated with high - profile disputes over biospecimens collected in research, including the havasupai case and the lacks family settlement . These events have consequences for the researche... |
Protein sequencing by tandem mass spectrometry (ms / ms) has evolved into a standard and widely applied method [1, 2]. The most common approach in ms - based proteomics involves digestion with specific enzymes after performing a reduction / alkylation step, referred to as bottom - up or peptide - centric readout [35]. ... |
One of the most common fracture pattern is a simple lateral split (ao / ota type 41-b1.1, schatzker type i).this type of fracture usually occurs in two different groups: young patients after high - energy trauma or elderly osteopenic patients after low - energy injuries . In the latter, a depression component is often ... |
To achieve an accurate pathological evaluation in toxicity studies, it is particularly important to know the background histopathology, that is, to be familiar with pictures of incidental findings . As abundant studies using rats are common in laboratories, toxicological pathologists know the background data of spontan... |
Experiments were carried out using polystyrene nps with either an anionic, carboxylate - modified or cationic, amine - modified surface (table 1). Dark, nonfluorescent nps were used for experiments in which the np fluorescence would interfere with the measurement . We use the diameter supplied by the manufacturer, whic... |
Suicide is an important public health problem both in developing and developed countries, which accounts for more than 80000 annual deaths worldwide (1).in 2008, the suicide rate for the world was reported to be 11.6 per 100,000 population (2). However, the number of suicide cases has been rising and it is predicted to... |
This research work was supported by the office of the national research council of thailand and the faculty of pharmacy, silpakorn university, nakhon pathom, thailand. |
Postcholecystectomy bilomas are relatively uncommon with a reported incidence of about 2.5%, and most often present with right upper quadrant pain and fever within seven days of the operation . The authors report a case of a cholecystectomy performed in a 35-year - old female which resulted in a biloma, presenting 11 d... |
Routine vision screening evaluations, typically performed at well child visits by the pediatrician or at school by a licensed heath care personnel, are a beneficial and cost - effective means to identify children that require care from an eye specialist . Young children may be unaware and/or unable to identify problems... |
Human cytomegalovirus (hcmv) is one of the prevalent opportunistic pathogen that causes a wide spectrum of clinical manifestations (1). This virus is regarded as the main morbidity and mortality cause in immune suppressed patients (ie; organ transplant recipients, human immunodeficiency virus (hiv) patient) (2). Newbor... |
The sample population included 18 to 45 year old subjects living in tabriz, north - west of iran in 2009 . A sample size of 400 subjects was estimated prior to the study according to the cochrane formula considering p as 0.04, d as 0.02, and as 0.05 . A two stage cluster sampling method with a probability postal codes ... |
Congenital midline nasal masses are rare developmental anomalies estimated to occur in one out of every 20,000 - 40,000 births . A nasal dermoid cyst (ndc) typically presents as a midline mass located anywhere from the glabella to columella . The majority of ndc's are diagnosed in infancy and early childhood, but in so... |
The domesticated silkworm, bombyx mori, which has been reared by humans for more than 5000 years, is an agriculturally important insect and has economically important values in sericulture . In addition, the silkworm is a key model of the lepidoptera, a group of holometabolous insects . Bombyx mori nucleopolyhedrovirus... |
Esthetic considerations and dental appearance have become very important for children and adolescents, who are therefore strongly motivated to seek orthodontic treatment.1 the number of children and adolescents seeking orthodontic treatment has dramatically increased over the past few decades; however, not all of these... |
Cerebral white matter injury (wmi) is recognized as the most common form of injury to the developing brain of neonates, especially survivors of preterm birth1). Although multiple factors are involved in brain injury, both infection and inflammation are well - established risks factors for wmi in the preterm population2... |
The conceptual emphasis of addressing the issues of the tooth or orofacial structures along with the concerns of the person involved has been the basis for providing health care in dentistry . Dental education and practice have been acknowledged as one of the most challenging, demanding, and stressful fields.1 - 4 many... |
A randomized split mouth - controlled clinical study was conducted to evaluate the effectiveness of curcumin strip in the treatment of chronic periodontitis compared to srp alone . The study - related procedures were explained to the patients before they signed an informed consent form . A total of twenty subjects of a... |
Repeat expansion disorders are caused by mutations in dna where repeats in certain genes become expanded . Once the repeats are transcribed, mrna (mrna) folds into a hairpin with repeating internal loop motifs, which can be translated into toxic proteins or sequester proteins and cause disease . One hypothesis is that ... |
The systematic review was carried out according to the preferred reporting items for systematic reviews and meta - analyses (prisma) guidelines5 . Three databases, namely, medline / pubmed, google scholar and science direct were searched and all studies on pioglitazone carried out in india published in english language... |
Canagliflozin (invokana) is a novel therapy for type 2 diabetes mellitus (dm) approved in a new class acknowledged as sodium - glucose co - transporter 2 (sglt2) inhibitors . Canagliflozin inhibits the glucose reabsorption by the kidney, increasing glucose elimination and reducing blood glucose levels in diabetic patie... |
With the widespread use of highly active antiretroviral therapy (haart), the life expectancy of hiv - infected persons in the united states has increased markedly . Hiv - infected persons are at higher risk for cancer compared with the general population [2, 3]. Utilization of highly active antiretroviral therapy (haar... |
According to analyses of the world health organization (who), more than 800 000 people died from suicide in 2012, and the number of attempted suicides is estimated to be about 20 times higher . However, the lethality of suicidal behavior is clearly higher in males, resulting in higher rates of completed suicides than i... |
Multiple myeloma (mm) is a neoplasm of plasma cells accounting for 1015% of hematopoietic neoplasms . It is more common in people of african descent, occurring twice as frequently compared to caucasians . Plasma cell leukemia (pcl) is a very rare type of mm characterized by high numbers (> 20%) of circulating plasma ce... |
The entry of contaminants into the environment due to human and natural activities is one of the most important issues facing today's communities . Due to the industrial and economic growth and the production of a variety of compounds and chemicals followed by increased consumption man makes some unwanted pollutants, m... |
Chemotherapy remains the main treatment option for most cancers despite of its limitations, such as systemic toxicity, severe side effects, and limited efficacy . The major reason for chemotherapy failure is poor delivery of drug to cancer cells and/or intracellular targets . There are a number of barriers that have to... |
Palatal myoclonus is a movement disorder in which there are rhythmic jerky movements of the soft palate . It is generally classified as somatosound or objective tinnitus and is rare compared to sensorineural tinnitus or subjective tinnitus . According to etiologic factors, platal myoclonus has been classified as two di... |
Urinary tract infections (utis) account for 8.3 million doctor visits yearly in the united states and are the second most common type of infection in the body . It is one of the most serious health problems affecting millions of people each year . Utis include acute as well as chronic cystitis, prostatitis, pyelonephri... |
Jacob arthurin 1827 first coined the term rodent ulcer to describe what we now know as a basal cell carcinoma (bcc). It is the most common cutaneous malignancy worldwide, accounting for 6575% of all skin cancers . Gross differences are noted in the percentage of skin cancer in the asians (24%) and blacks (1 - 2%) as co... |
Anesthesia has the potential to induce physiological changes that may lead to morbidity and mortality . As a result a number of investigators, however, have reported that anesthesia - related mortality rates have declined over the past two decades . This decrease has been attributed to a variety of safety improvements ... |
A functioning vascular access is essential for effective delivery of hemodialysis and, understandably, lack of vascular access or complications developing in an existing vascular access are associated with significant patient morbidity . Thrombosis is one of the most common complications associated with autologous arte... |
Host - seeking mosquitoes were collected in and around grand forks, north dakota, by using mosquito magnet traps (american biophysics corp ., north kingston, ri, usa) for 4 transmission seasons, from early summer 2002 through fall 2005 . Mosquitoes were sorted by species and tested for wnv by using reverse transcriptas... |
Keishibukuryogan (kbg, gui - zhi - fu - ling - wan in chinese) is one of the kampo medicines, and has been widely administered to patients with blood stagnation for improving blood circulation . It was reported that kbg improves conjunctional microcirculation in patients with cerebrospinal vascular diseases, thus sugge... |
Spondylocostal dysostosis (scdo) is a rare, heritable axial skeleton growth disorder characterized by malformed vertebral column and ribs, abridged thorax, and kyphoscoliosis . We present here an infant with scdo with neural tube defect who underwent lipomyelomeningocele excision and detethering of the cord . An 8-mont... |
Since the introduction of two cognitive - behavioral models of social anxiety in the 1990s (clark and wells 1995; rapee and heimberg 1997), a proliferation of studies have focused on the cognitive aspects of social anxiety as described in these models (schultz and heimberg 2008). The cognitive - behavioral models descr... |
Neurilemmoma is defined as " a neoplasm that arises from schwann cells of the cranial, peripheral, and autonomic nerves " . Clinically, these tumors may present as cranial neuropathy, abdominal or soft tissue mass, intracranial lesion, or spinal cord compression . The terminology regarding neurilemmoma may be confusing... |
Recently, nanostructure mesoporous materials have attracted much attention for development of catalytic and adsorption systems . Mesoporous materials have often been functionalized by adding noble ligands to improve their physical and chemical properties [13]. Santa barbara amorphous (sba-15) is a highly ordered materi... |
Kyrle's disease (kd) is a rare skin disorder characterized by transepidermal elimination of abnormal keratin . It is classified as a subtype of acquired perforating dermatosis along with reactive perforating collagenosis, elastosis perforans serpiginosa and perforating folliculitis . It is commonly seen in patients wit... |
Lipomasare slow growing fatty tumours of mesenchymal origin and can occur in any organ of the body . Spindlecell lipomas (scls) are lipoma variants which have the potential of neuromuscular invasion despite their benign histopathology . This case report highlights a spindle cell lipoma variant in the supraclavicular ar... |
We conducted a preliminary comparison of the relative sensitivity of a cross - section of published hrv - specific pcr primer pairs (most of which were first published before hrv - c was reported), independent of most variables described above, by testing a panel of 57 clinical specimen nucleic acid extracts from combi... |
During the first decade of the 21st century, global health became prominent on the international political agenda (fidler, 2005) and international financial assistance for health increased substantially (institute for health metrics and evaluation, 2010). According to fidler (2005) this was nothing less than a global h... |
The intra - aortic balloon pump (iabp) is used to increase myocardial oxygen perfusion, while at the same time increasing cardiac output and decreasing the workload of the ventricle . Several parameters affect iabp treatment, such as the volume of the balloon, its location in the aorta, its rate of inflation and deflat... |
Snoring is caused by vibration of the soft tissue during sleep while breathing within extrathoracal respiratory tract . Pathological reasons for the noise include tension loss in the oropharyngeal muscle due to disturbed innervation, degenerative processes, tumours, and changes in the mucous membranes . In general, the... |
As the global suicide rate increases by 60% in 50 years in the underdeveloped and developing countries, paraphenylenediamine (ppd) poisoning is emerging as an important etiological factor reported from india . Ppd ingestion is a very common form of poisoning in india as this compound is a component of hair dyes and is ... |
Crystal nucleation in liquids has countless practical consequences in science and technology, and it also affects our everyday experience . One obvious example is the formation of ice, which influences global phenomena such as climate change, as well as processes happening at the nanoscale, such as intracellular freezi... |
The prevalence varies between 0.6% and 1.3% in various series.1)2) anomalous origin of a coronary artery from the opposite sinus of valsalva represents small fraction of these anomalies.3) although most instances of anomalous origin of the coronary artery are unlikely to have any clinical sequelae, a few are potentiall... |
Postural control is essential in performance of independent activities of daily living in stroke patients1 . Postural control is defined as the ability to maintain the center of mass (com) within the base of support with minimal postural sway, and the sensory systems (visual, somatosensory, and vestibular systems), cog... |
Bone involvement in epithelial ovarian cancer is very unusual, with several series noting an incidence of <2% [1, 2]. A recently encountered ovarian cancer patient who was found to have significant bone involvement at the time of disease recurrence, after an extended treatment - free interval, emphasizes the potential ... |
The original investigations showed that ced-3 and ced-4 genes play essential roles in either the initiation or execution of the cell death program during the development of the model organism nematode caenorhabditis elegans (c. elegans). Further study proposed that ced-3 acts as a cysteine protease in controlling the o... |
Trypanosomiasis has been endemic in zambia for a long time . The great african rinderpest pandemic which wiped out most of the ungulate population in the late 1880s contributed to the decline of the wildlife and tsetse distribution in zambia [1, 2]. As a result, eastern zambia was largely free of tsetse making cattle r... |
Addiction is one of the most important health problems in the world, specially in iran (1), and many factors are related to onset and maintenance of this common disorder . Since the ancient times, philosophers and scientists have known loneliness as one of the most complex psychological phenomena . At that time lonelin... |
Rhodiola rosea (r. rosea) is an herb that grows in mountainous regions of north america, europe, and asia . It has been used in traditional folk medicine for centuries as a treatment for fatigue and mood disorders . R. rosea has been extensively studied by scientists in the former soviet union and has predominantly bee... |
Postprandial glucose homeostasis is controlled by insulin release in response to the absorbed nutrients and to gastric inhibitory polypeptide (gip) and glucagon - like peptide 1 (glp-1) [14], which are responsible for the so - called incretin effect, that is, the enhanced insulin secretion after oral versus intravenous... |
Beta - thalassemia major is an autosomal recessive hereditary anemia, which is incurable, caused by defective synthesis of hemoglobin, ineffective erytropoiesis and rapid erythrocyte breakdown, resulting in advanced heart failure and death in early childhood[1, 2]. The combination of transfusion and chelation therapy h... |
Juvenile idiopathic arthritis (jia) is a chronic and progressive inflammatory arthritis of childhood which often results in persistent and disabling foot impairments [13]. Synovitis, has a predilection for the lower limb joints and results in well - recognised clinical features including joint pain, swelling, limited j... |
In the last decade, the prevalence of dementia was rapidly growing with a considerable impact on daily live of all involved parties including the broader community . Due to the overcrowd in residential care and to emotional restraints in family carers to have their relative with dementia admitted, dementia patients are... |
Morphological changes including disruptions of sarcomeres, cytoskeletal elements, and sarcolemma are accompanied by muscle damage . Loss of muscle function such as reduced force production, an indirect marker of muscle damage, is followed by delayed - onset muscle soreness (doms) and leakage of muscle proteins includin... |
Angiomatosis is a complex vascular malformation of infancy and childhood consisting of proliferating blood vessels with accompanying mature fat, fibrous tissue, lymphatics and nerves which may involve skin, subcutaneous tissue, skeletal muscle and occasionally bone . It is extremely rare and benign but a clinically ext... |
Cardiovascular disease (cvd) is the largest killer of women internationally . Women often suffer inferior outcomes following an acute cardiac event as compared to men and are often diagnosed less promptly and treated less aggressively . Fewer women attend cardiac rehabilitation (cr) than men, despite its proven benefit... |
Clostridium perfringens, which was previously known as clostridium welchii, is a gram - positive, anaerobic, non - motile rod - shaped bacterium and is able to form environmentally resistant spores (1). This ubiquitous microorganism could be found in a variety of habitats such as soil, water and lower mammals and human... |
Coronary heart disease (chd) is the second leading cause of death among chinese adults now - a - day . Health - related quality of life (hrqol) is useful for assessing the socio - economic impact and burden of illness, effectiveness of interventions and treatments, and long - term mortality among patients after a cardi... |
Infantile hemangiomas (ihs) are common, benign vascular tumors of infancy, 5060% of which affect the head and neck area . Although usually innocuous and self - limiting, they can cause serious complications such as airway compromise, visual loss, severe anemia, and high - output cardiac failure . Till recently, treatme... |
A 15-year - old adolescent (weight, 46 kg; height, 162 cm) had a medical history of hypertension, cyclic headache, and vomiting for 10 years without an awareness of his medical condition . Thereafter, he demonstrated a seizure with subcortical ich in the left frontal area 6 weeks before the surgery . He was diagnosed w... |
Due to its significant ability to up - regulate or acquire resistant determinants, there are serious challenges associated with choosing and monitoring appropriate antibiotic treatments (1). Although carbapenems are generally considered to be the most promising antibiotic to use against acinetobacter baumannii, the inc... |
Before the introduction of diffusion tensor imaging (dti), accurate evaluation of the ascending reticular activating system (aras) in the live human brain was limited . Recently, diffusion tensor tractography (dtt), which is derived from dti, has enabled 3-dimensional reconstruction and estimation of the aras in the hu... |
Sarcoma is a heterogeneous group of cancers of the soft tissue and bone, and some are extremely rare . The rarity and diverse characteristics of sarcomas has impeded the development of new treatments . Doxorubicin and ifosfamide, either alone or in combination, have been the backbone of metastatic soft tissue sarcomas ... |
Adolescents constitute 20% of the world population and are estimated to be 1.13 billion by the year 2025 . Adolescence is a period of rapid growth and development by which up to 45% of skeletal growth takes place and 15 to 25% of adult height is achieved [1, 3]. In addition to the increased nutritional requirements dur... |
Anaplastic thyroid cancer (atc) is one of the most aggressive tumours known in medicine . Even though a multimodal approach is used in treating these patients, average survival rate is expressed in months, and one - year survival is 15% [1, 2]. Fortunately, atc is a very rare malignancy with an incidence of roughly 2 p... |
Expansion and proliferation of insulin - secreting beta cells in pancreatic islets is a key highly regulated mechanism for establishing, maintaining, and adapting islet function to meet organism physiological demands . Understanding how the pieces of this mechanism fit together could improve development of islet replac... |
Lupus mastitis presents as single or multiple subcutaneous or deep breast masses, clinically mimicking malignancy [figure 1]. Lupus mastitis presenting as the initial manifestation of lupus erythematosus (le) is very rare . Later, she developed discoid le (dle) lesions on breast and other sites without any systemic sym... |
Human multipotent mesenchymal stromal cells (msc), known for their multilineage differentiation potential, possess pleiotropic immunosuppressive functions that are partly mediated by expression of the tryptophan - catabolizing enzyme indoleamine-2,3-dioxygenase (ido) [14]. Upon stimulation with inflammatory cytokines, ... |
Bilateral hearing loss represents a great disability for patients with neurofibromatosis type 2 (nf2) and patients with vestibular schwannoma (vs) in the only hearing ear . The treatment for vs patients (unilateral and bilateral) is diverse, including observation, surgery, and radiotherapy . Treatment of the worst hear... |
Regular home oral care and a yearly dental check - up are the best means for saving one s own teeth, but it appears that in spite of the information on adequate dental care provided by the dental professional and the mass media many people fail to take these precautions . Although social factors are included in several... |
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