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Asthma is a chronic disease characterized by a variety of features including increased airway responsiveness and reversible airways obstruction and inflammation (1). Studies on animals and humans have shown that bronchoconstriction is most likely due to the release of inflammatory mediators from different cells (2). Al... |
Brds have an important role in the targeting of chromatin - modifying enzymes to specific sites . Often they act with other protein - interaction modules to guarantee a high level of targeting specificity for these essential enzymes . For example, the methyltransferase ash1l contains a combination of one brd and one pl... |
During 20092010, an outbreak of dengue fever occurred in key west, florida (9). Shortly thereafter, the florida keys mosquito control district proposed the first release of a gm mosquito, ox513a ae . The proposal was met with controversy . On publication of this article, the release was undergoing inspection by the us ... |
Idiopathic macular epiretinal membrane (ierm) is a relatively common disorder, with an incidence reaching 12% in those older than 70 years . On one hand, ierm seems to begin with microfractures in the inner retina after posterior vitreous detachment, while, on the other hand, it seems to occur when the external layer o... |
The role of targeted therapies in medical oncology has tremendously increased over the last ten years . A high number of novel molecular substances have already been approved for clinical use and several compounds are in ongoing trials at present (1,2). Despite some very successful therapeutics like the tyrosine kinase... |
The antimicrobial peptides (amps) are biologically active molecules produced by wide variety of organisms as an essential component of their innate immune response . The primary role of the amps is host defense by exerting cytotoxicity on the invading pathogenic microorganisms, and they also serve as immune modulators ... |
Case one was 13 years old and had severe sudden onset low back pain with radiation to anterior aspect of right thigh during extension of leg . Computerized tomography at l2-l3 level (figure 1) showed a bony fragment similar to an osteophyte extending to canal . In lumbosacral mri we detected a l2-l3 disc bulging with i... |
Various large - scale and high - throughput techniques, such as chromosome banding (1,3), comparative genomic hybridization (cgh) (4) and fluorescence in situ hybridization (fish) (5), are being used in modern cancer cytogenetics to detect structural and copy number changes in chromosomes . The most common type of muta... |
This study was based at the armed forces research institute of medical sciences (afrims)kwai river christian hospital clinical center, sangkhlaburi district, kanchanaburi province, thailand . (the protocol was approved by the human subjects research review board of the u.s . Army, ethical review committee for research ... |
Transgenic mice are sacrificed using carbon dioxide gas, followed by decapitation and the brain extracted . The other will be submerged in 4% paraformaldehyde (pfa) for at least 48 hours at 4c . After fixation in 4% pfa for at least 48 hours, the hemi brain is transferred directly into 30% sucrose solution and placed a... |
Systemic lupus erythematosus (sle) is a systemic autoimmune and inflammatory disease that affects many organs and systems through formation and deposition of autoantibodies and immune complexes leading to severe tissue and organ damage [1, 2]. It is characterized by hyperreactivity of t and b cells and a failure to eli... |
Aquaporins belong to a family of membrane proteins that passively transport water, glycerol, and other small molecules (nielsen et al ., 2002). The archetypical water channel aqp1 has been shown to be highly specific for water and excludes protons, ammonia, and sugars such as glycerol (zeidel et al ., 1992, 1994). The ... |
A total of 1,633 male body weight (bwt) and age measurements, for 232 thoroughbred colts, were collected by the japan bloodhorse breeders association (jbba) between 2005 and 2009 . The data with extreme values over 4 residual standard deviations were preliminary analyzed by using logistic growth curve equation, and rem... |
Gastric cancer is one of the most common types of cancer and often spreads from the stomach to other parts of the body, particularly to the liver, lungs, bones, the abdominal lining, and lymph nodes . During the last decade, considerable research has been conducted on the induction of apoptosis by traditional chinese m... |
Chironomus riparius (chironomidae, diptera), is widely used in aquatic exotoxicological studies for assessing acute and sub - lethal toxicities of contaminated sediments and for water monitoring due to their widespread occurrence, short life - cycle, easy to be reared in the laboratory, physiological tolerance to vario... |
The biomedical community has traditionally used two types of ceramic implants for bone tissue regeneration technologies: inert materials such as alumina, zirconia, and carbon (hulber 1993; wise et al 1995) and bioactive ceramics (vallet - reg 2001a), which interact with the physiological environment when implanted lead... |
The reconstruction of the distal dorsal fingers is difficult as the fingertip skin is hard and inflexible. [14] we have experienced cases of minor distal dorsal finger skin defects due to digital mucous cyst (dmc) excision . In addition, some studies on the operative procedures of digital dorsal finger reconstruction h... |
Hypertension is a common and major public health problem associated with a high level cardiovascular morbidity and mortality worldwide . It remains the major risk factor for heart failure, stroke, coronary artery disease, and chronic renal failure in nigeria . Hypertension which was initially considered rare in sub - s... |
Breast cancer is the most common type of malignancy and one of the major causes of death in women worldwide . In advanced nations, breast cancer is a very frequent malignancy diagnosed among women, and in the developing nations, it is placed second to cervical cancer (1). Breast cancer is also the primary cause of canc... |
It is the second most abundant transition metal ion in living organisms, including humans . Zinc is present in all the tissues, fluids, and organs within the human body, for a total body content of approximately 1.42.3 g. it is necessary for catalytic, structural, and regulatory functions in hundreds of enzymes and in ... |
Celiac disease (cd), an inflammatory disorder of the upper small intestines, is characterized by intestinal villous atrophy and crypt hyperplasia and is caused by an abnormal immune reaction to wheat gliadin . It may be associated with different symptoms and signs, depending on the degree of intestinal involvement . Th... |
Capmul mcm was gifted by abitec corporation, usa . Tween 20 and peg 400 were purchased from sulab chemicals, vadodara, india . All the other reagents were analytical grade . For the selection of components of microemulsion, solubility study was carried out in number of components according to procedure given by lianli ... |
Resin cements are composite resins developed to deliver mechanical properties and handling characteristics that are important for luting indirect restorations . Due to their application under an indirect restoration, in most cases the physical activation (photo activation) has very limited effect . Activation of the po... |
Acute lymphoblastic leukemia (all) in adults accounts for 15% of acute leukemia .total body irradiation (tbi) for adult patients with all is a vital technique used prior to bone marrow transplant . A total body irradiation regime is used in the treatment of all to destroy malignant cells and to suppress the immune syst... |
At least one week was spent in each tc, evaluating infrastructure, policies and procedures, treatment and rehabilitation programs, and staff competencies . Many tools were used in the evaluations, including questionnaires for residents and treatment teams; interviews with directors, treatment teams and residents; obser... |
The main aim of radiotherapy is to maximize the tumor control probability with less complication to the surrounding critical structures . A treatment plan is generated based on this simple rule and several methods of treatment delivery techniques, including 3d conformal radiotherapy, intensity modulated radiation thera... |
High - titer engineered retrovirus (110unit / ml) is produced by co - transfection of retroviral vectors and vsvg into hek293 t cells, followed by ultracentrifugation of viral supernatant . For sources and production methods, see the excellent jove demonstration (3). Note: young adult (4 - 6 weeks old) female c57bl/6 m... |
A 35-year - old healthy lady presented with high grade fever, severe abdominal pain, nausea, vomiting and profuse watery diarrhea, sometimes green in color . There was no history of animal contact, recent travel or camping . On exam, the patient was hypotensive and was looking acutely ill . She also had hypokalemia of ... |
Iranian ministry of health and medical education (mohme) began implementation of primary health care as the main theme of the healthcare networks to provide health services for all people in 1977 . Government policy in the health system was based on three major axes: priority of preventive services to health care servi... |
This retrospective study was performed at the l. v. prasad eye institute in india from september 2012 to january 2013 . Prior approval from the institutional review board of the institute was obtained, and informed consent was obtained from each study subject for the diagnostic procedures . Fifty - one eyes (26 patient... |
A retrospective, comparative cohort study was conducted on patients who underwent 152 primary pcl reconstruction surgeries performed by a single surgeon between april 2004 and october 2008 . Grade ii pcl injuries combined with other ligamentous or grade iii pcl injuries were considered for surgical treatment when the p... |
Commercial porcine vaccines and viruses a total of 25 commercially available porcine vaccines were obtained from licensed manufacturers and pharmaceutical suppliers in taiwan (table 1). Viral dna was extracted from each vaccine using the qiaamp dna extraction kit (qiagen, usa) according to the manufacturer s instructio... |
Idiopathic sudden sensorineural hearing loss (issnhl) is one of the emergent conditions among various otologic diseases . It is the acute onset of hearing loss of 30 db in three contiguous frequencies, which may occur instantaneously or progressively over several days (1). It occurs mostly unilaterally, with a bilatera... |
Attenuated familial adenomatous polyposis (afap) is a milder variant of familial adenomatous polyposis (fap), which manifests with fewer than hundred colorectal polyps, later age of onset of polyps and cancer, and a predilection toward involvement of the proximal colon in clusters.1 - 5 much of mutations in afap have a... |
Blood samples: heparinized blood samples were collected from cattle with swallowing difficulty and from asymptomatic cattle from the same cowsheds where the affected cattle were raised . The sampling was conducted on the two farms (farms a and b) where the clinical cases were observed, on october 25 and 31, respectivel... |
In addition to classical endpoints, toxicogenomics methods have been used to characterize the assays and to classify toxicants . For regulatory purposes, the descriptive data from, e.g., transcriptomics or metabolomics approaches need to be converted to quantifiable measures allowing one to compare and predict the haza... |
Chronic hepatitis c virus (hcv) infection has a detrimental effect on the health of persons with chronic kidney disease . It leads to higher mortality in maintenance hemodialysis patients compared to noninfected patients and reduces the survival rates of patients undergoing kidney transplantation as well as their graft... |
Arsenic is a toxic metalloid [1, 2] that exists throughout nature in organic and inorganic forms . It is commonly present in soils on average at several mg / kg, as well as in marine sediments, and is enriched in mineral deposits as oxides and sulfides . The basic element, arsenic, exists in either of three allotropic ... |
In july 2007, an outbreak of ulceroglandular tularemia occurred in utah among visitors to the southwest shore of utah lake; an epidemiologic investigation implicated deer fly bites as the source of infection (8). Molecular subtyping of isolates was performed by using pmei pulsed - field gel electrophoresis (pfge) as pr... |
In recent years, growth in the aging population has been observed in many countries and is progressing rapidly in japan in particular . Because of this, the incidence of dementia in particular, alzheimer s disease (ad)is rising rapidly, so there is a pressing need to provide effective treatment options for individuals ... |
In human, nkg2d ligands consist of two families; the mhc - class - i- chain - related proteins (mica and micb) [1, 2] and the cytomegalovirus ul16-binding protein family (ulbp16) or retinoic acid early transcript 1 (raet1e, g, h, i, n, and raet1l) [3, 4] which are polymorphic [57]. The signaling through nkg2d engagemen... |
The american college of sports medicine (acsm) recommends that healthy adults should participate in moderately intense aerobic exercise, defined as 64 76% of one s maximal heart rate, for at least thirty minutes, five days per week . This is considered the minimum threshold of aerobic exercise for one to maintain healt... |
The ludwigshafen risk and cardiovascular health (luric) study is a prospective cohort study designed to evaluate determinants of cardiovascular health (1517). Between july 1997 and january 2000, 3,316 caucasian subjects referred for coronary angiography were recruited at the herzzentrum (cardiac center) ludwigshafen in... |
The use of autogenous bone grafts with osseointegrated implants was originally discussed by breine and branemark in 1980 . Since then, numerous papers have been published that have presented a variety of procedures involving different types of implants, bone grafts, and other graft materials for oral and craniofacial r... |
Congenital hypothyroidism (ch) is a condition of insufficient production of a thyroid hormone, which is due to thyroid dysgenesis or thyroid dyshormonogenesis . It results in irreversible damage of the central nervous system (porterfield, 1994), presenting serious mental and motor retardation (simic et al ., 2009). Neo... |
Because the functional and morphological diversities of an organism represent the value of the organism itself, the traditional biological techniques used to characterize these properties provide indispensable information . Conventional biology techniques face difficulties, however, such as classifying characterless or... |
In 2009, the world faced the emergence of a new strain of influenza virus (1). The influenza a (h1n1) virus spread rapidly, causing the first pandemic of the 21st century (2). In brazil, the first confirmed case of infection with the new virus was reported on may 7th, 2009 by the brazilian health minister (3). On july ... |
Cadmium (cd) is often the result of environmental pollution caused by industrial and agricultural activities and it is widely dispersed into the environment; hence, humans are exposed to it ubiquitously . An earlier study showed that cd acts as a stressor and leads to metabolic alterations . Humans always come into con... |
Pregnancy is associated with an increased risk of thrombosis among women with mechanical prosthetic heart valves . An anticoagulation management is important for both, mother and fetus.1) an increased thrombogenicity in pregnancy may be associated with several factors such as inherited coagulation defects, which may re... |
Gastric cancer is one of the most common fatal cancers, and patients are particularly prone to lymph node metastasis.1 the incidence for gastric carcinoma has had a recent increase, likely due to both environmental and social factors.1 effective methods for early diagnosis, monitoring metastasis, and prognosis are curr... |
Chemicals: all chemicals were purchased from sigma - aldrich corporation (st . Louis, mo, u.s.a .) Unless stated otherwise . Plant material, preparation and isolation of trans--viniferin: the leaf and stem of v. amurensis were gathered on keryong mountain in daejeon, korea . Botanical identification and isolation of tr... |
The following primary antibodies were used: mouse anti - wingless (1:1000 for standard protocol and 1:300 for extracellular staining; dshb 4d4), rabbit anti - ha (1:1000, cell signalling), rat anti - ollas (1:10, abnova), chicken anti - gfp (1:1000, abcam), mouse anti - integrin (1:100, dshb cf.6g11), mouse anti - dlp ... |
The aim of this report is to describe a single case of vitiligo induced by carbamazepine . The case was a patient with bipolar i disorder whose medications were changed from valproate to carbamazepine and who developed vitiligo after a short while . When depigmentation occurred, we immediately discontinued carbamazepin... |
Tubulointerstitial fibrosis (tif) is the final manifestation of end stage renal disease (esrd) and renal injury is correlated to the degree of renal interstitial fibrosis . One of the major pathological characteristics of tif is the activated tubulointerstitial fibroblasts transdifferentiating into myofibroblasts . Fur... |
Participants were recruited from two prospective studies: the prospective research in memory (prime) clinics study and the australian imaging, biomarkers and lifestyle (aibl) study of aging . Only data and biochemical measurements pertaining to baseline visits were included in this analysis . The prime study recruited ... |
The most prevalent fracture that trauma surgeons manage are those involving the distal radius, accounting for 16% of all fractures . Nonoperative management is generally employed for stable nondisplaced fractures of the distal radius with the expectation of a good functional outcome [35]. Although some authors suggest ... |
Interdigitating dendritic cell sarcoma (idcs) is a very rare neoplasm arising from interdigitating reticular cells, which participate in the immune response as antigen presenting cells that stimulate t lymphocytes [1, 2]. Tumor occurrence is usually seen at t - cell rich areas of lymph nodes in the cervical, mediastina... |
Chikungunya virus (chikv) is a positive - strand rna virus belonging to the genus alphavirus (1, 2). Transmitted by the aedes mosquito, while chikungunya fever (chikf) outbreaks were previously restricted to tropical regions, the range of chikv has since expanded to temperate countries such as italy (6) and france (7).... |
As people age, age - related changes of physical function affect their ability to walk1 . As the ability to walk in the elderly decreases, there is an associated decrease in balance ability2, 3 and independent daily living activities4 and increased risk of falling5 . Therefore, it is necessary for the elderly to mainta... |
Failure to respond to conservative and pharmacological treatment of oab has previously been described, but there is considerable heterogeneity in the definitions of both treatment response and nonresponse in trials involving patients with oab . Over the last few years several clinical studies have been published which ... |
During the past two decades there have been major advances in the pharmacological treatment of chronic heart failure . Despite this, severe heart failure remains a syndrome associated with very high mortality, profound reduction in quality of life, and frequent hospitalisation . Cardiac transplantation can be an extrem... |
Retinal angiomatous proliferation (rap) is a form of retinal - choroidal neovascularisation within the wet age - related macular degeneration (amd) category, characterised by intraretinal capillary proliferation, subretinal neovascularisation and a serous / vascularised pigment epithelial detachment including a retinal... |
Encapsulating peritoneal sclerosis (eps) is a rare but devastating complication of peritoneal dialysis (pd). Herein, we report a case of a patient undergoing 12 years of pd who developed eps and calciphylaxis simultaneously . We also provide a comprehensive discussion about the association between eps and calciphylaxis... |
The success of a dental restoration depends upon a number of factors such as the material chosen, its mechanical properties, anatomical form, surface texture, translucency and colour . The most common aesthetic restorative material used in day to day practice for crown and bridge work is porcelain fused to metal (pfm) ... |
Burning mouth syndrome (bms) is a burning or itching sensation in the normal oral mucosa . The pain is persistent, ranges from moderate to severe, and occurs particularly often in postmenopausal women . The international association for the study of pain defines bms, which is also called stomatodynia, glossodynia, oral... |
Angiogenesis is the formation of new capillaries by the budding of endothelial cells resident in the surrounding preexisting vessels . It is a complex process that involves endothelial cell division, selective degradation of vascular basement membranes and of surrounding extracellular matrix and endothelial cell migrat... |
Kidney (renal) cancer, which includes renal cell carcinomas and transitional cell carcinomas of the renal pelvis, is estimated to have caused 13 680 deaths (8780 men and 4900 women) in 2013 . Clear cell renal cell carcinoma (ccrcc) is the most common subtype of kidney cancer, contributing approximately 80% of all repor... |
Autism spectrum disorder (asd) is defined by persistent deficits in social communication and social interaction, and restricted, repetitive patterns of behavior, interests, or activities . There have been recent changes made to the diagnostic criteria, including modifications to the core features . Although an asd diag... |
Imaging modality is an important aspect of the image for medical retrieval [16]. In user studies, clinicians have indicated that modality is one of the most important filters that they would like to be able to limit their search by . Many image retrieval websites (goldminer, yottalook) allow users to limit the search r... |
Upon developing a rapid and efficient synthesis of 2,1-borazaronaphthalenes starting from simple, readily available starting materials, we subsequently developed the suzuki these studies demonstrated the stability of these azaborines to transition metal catalysis and allowed access to functionalized molecules that coul... |
Healthy people 2020 recently identified the importance of sleep in the health and well - being of americans.1 one objective set forth in this initiative is to increase the proportion of adolescents and adults who get sufficient sleep . Although sleep deprivation among adolescents is not a new phenomenon, in recent year... |
Trypsin (sequencing grade) was purchased from promega (madison, wi). Isotope - labeled peptides were obtained from new england peptide (gardner, ma) with either u c6, u n2-lysine (+ 8 da) or u c6, u n4-arginine (+ 10 da) at the peptide c terminus . Chemical purity was ranged from 95 to 99% and isotopic purity was great... |
All authors were involved in drafting the article or revising it critically for important intellectual content, and all authors approved the final version for publication . Dr . Fukui had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data anal... |
Tuberculosis is a major public health problem worldwide . Although tuberculosis is a treatable disease, there were 8.8 million cases of tuberculosis and 1.45 million deaths from tuberculosis in 2010 . With an incidence of 2.3 million cases, india has the highest burden of tuberculosis in the world, and one out of every... |
Acupressure and massage therapy are effective non - pharmacologic therapies and can be effective in reducing menstrual pain . The body's vital energy, called chi in chinese medicine, moves in the body pathways known as meridians . The increase or decrease of energy in each meridian can affect the health of specific org... |
Abdominal adipose tissue is composed of subcutaneous and visceral adipose tissue . Visceral adipose tissue can be subdivided into omental, mesenteric, and retro- or extra - peritoneal depots . Obesity is a known risk factor for various diseases, and measurements of adipose tissue are commonly used in obesity research .... |
Multiple sclerosis (ms) is an inflammatory disorder of the central nervous system (cns) which causes progressive neurological disability over time . Affecting more than two million people worldwide, ms is recognized as the leading cause of nontraumatic neurological disability in young adults . For many patients, clinic... |
Transgender women (ie, male - to - female) have one of the highest incidence and prevalence of hiv infection in the united states and around the world . Preexposure prophylaxis (prep) with tenofovir disoproxil fumarate (tdf)emtricitabine (ftc) is a promising modality to curb hiv incidence in this population, but prep s... |
This work was supported by the seed fund from the mechanobiology institute at the national university of singapore. |
The site of capture of flounder in the mersey estuary (and in nearby liverpool bay), the method of capture, and the method of sample collection are described in previous articles (allen et al . Data on vtg concentrations used in the present study were taken from these previous studies . However, the analysis of data by... |
A sensitive scalp is a frequent problem in daily clinical practice and often represents a major challenge for dermatologists . In particular, patients with hair loss or alopecia frequently also complain of scalp problems that must be taken into account for a successful treatment program . The main complaint of these pa... |
Interferon tau (ifnt) is produced by trophectoderm cells of conceptuses of ruminant species and is the maternal recognition of the pregnancy signal . Besides its critical roles in implantation and establishment of pregnancy in ruminants [1, 2], it has a plethora of physiological functions in various cell types such as ... |
Opioid receptors in the periaqueductal gray (pag) contribute to a wide range of behaviors . These include nociceptive modulation, cardiovascular regulation, thermoregulation, and locomotor activity [15]. Although mu - opioid receptors (mor) are known to contribute to pag mediated antinociception [6, 7], less is known a... |
Selaginella doederleinii hieron, as a traditional chinese medicine, is a well - known perennial pteridophyte plant growing in south and southwestern china at the low altitude . It has the function of eliminating wind, scattering frigidity, detumescence, and treating cough . In the reported research, different types of ... |
The study of transcriptional mechanisms of addiction is based on the hypothesis that regulation of gene expression is one important mechanism by which chronic exposure to a drug of abuse causes long - lasting changes in the brain that underlie the behavioral abnormalities that define a state of addiction.1,2) a corolla... |
It is a chronic inflammatory disorder affecting both the hair follicles and the nail apparatus, with t - lymphocyte infiltration and chemokine expression being characteristic in involved tissue (1). The prevalence rates of aa is 0.1% in the world population (2) and 0.9 - 6.9% in korea (3). The association of aa with au... |
Total hip arthroplasty (tha) is widely performed for the purpose of alleviating pain and improving activities of daily living (adls). It is important to repair the hip center and lever arm that cause decreased mechanical efficiency due to hip deformity and to improve mechanical efficiency when reconstructing hip joint ... |
Although uterine rotation due to a myoma is a rare complication of pregnancy 1, obstetricians should be alerted to avoid making an incorrect uterine incision during cesarean section . A 35-year - old woman (gravida 1, para 0) was referred to our hospital for delivery because her pregnancy was complicated by a left - si... |
Consistent and replicable mechanical force on target spinal tissue is critical for minimizing functional and histological variability and for establishing successful contusive spinal cord injury (sci) models . The amount of force applied to a target region of the spinal cord depends on the methods utilized for spine st... |
The majority of these studies were conducted with adult male sprague - dawley rats from a selective - breeding colony which has been previously described14 . Selectively - bred rats from generations s18, s20 and s21 were transported from the university of michigan (ann arbor, mi) to the university of washington (seattl... |
Uterine artery fibroid embolisation (uae) has now been used in clinical practice for> 2 decades in the management of symptomatic uterine fibroids [1, 2]. It is estimated that> 50,000 procedures have been performed worldwide since ravina reported his series in france in 1995 [3, 4]. Uae is emerging as an effective alter... |
Pulmonary hypertension (ph) can be described as a complication caused by progressive obstruction and obliteration of the pulmonary arteries, ultimately leading to a progressive rise in pulmonary vascular resistance (pvr) and right ventricular (rv) failure and death . Ph may be classified into five categories: group 1 -... |
We used statewide reported ntm isolate data from all laboratories in oregon collected during 20072012 . From these data, we defined disseminated ntm as a reported ntm isolate from blood, cerebrospinal fluid, bone marrow, lymph node, or other sterile site in an oregon resident> 18 years of age . In a sensitivity analysi... |
A promising strategy for the treatment of neurodegenerative diseases involves pharmacologically induced activation of a coordinated antioxidant genetic program to shift the intracellular redox balance towards a homeostatic state by means of expression of detoxifying proteins and antioxidant enzymes . A key transcriptio... |
Search is a multicenter study that conducts population - based ascertainment of nongestational cases of physician - diagnosed diabetes in youth age <20 years at diagnosis (15). A total of 402 search participants with type 1 diabetes, residents of colorado and ohio, who had a duration of diabetes of at least 5 years, we... |
The authors retrospectively reviewed the medical records of 75 eyes from 75 consecutive patients with exudative amd who were treated only with intravitreal injections of 2.5 mg of bevacizumab between 1 january, 2006, and 31 june, 2008, at the vitreoretinal clinic of the inha university hospital, incheon, korea . The st... |
The biogenesis and function of eukaryotic mrnas involves a diversity of biochemical reactions . These include capping, splicing, and polyadenylation in the nucleus, as well as transport to the cytosol, where the mrna is engaged in translation before ultimately being degraded . In each case, the biochemical reaction and... |
Mycoplasma pneumoniae (mp) is one of the most common respiratory tract pathogens in community - acquired pneumonia (cap) patients . As one of the smallest bacterial organisms, mp is recognized as a capable of existence in both extracellular and intracellular environments which might facilitate the establishment of late... |
The last decade or so has seen substantial interdisciplinary activity between the arts and sciences, with many scientists applying knowledge and methods from their own areas in order to gain new insights into how art is made and appreciated (journal of consciousness studies, 1999, 2000, 2004; zeki, 1999; livingstone, 2... |
A continuous hydrolipidic film, representing the actual interface between the epidermal viable layers and outer environment, covers human skin . Skin surface lipids (ssls) are a mixture of sebaceous and epidermal lipids, displaying a very peculiar composition as compared to lipid fractions of serum or internal tissues ... |
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