pdb
stringlengths
4
4
Hchain
stringclasses
59 values
Lchain
stringclasses
60 values
model
int64
0
76
antigen_chain
stringclasses
386 values
antigen_type
stringclasses
24 values
antigen_het_name
stringclasses
240 values
antigen_name
stringlengths
1
396
short_header
stringclasses
448 values
date
stringlengths
8
8
compound
stringlengths
4
243
organism
stringlengths
3
175
heavy_species
stringclasses
121 values
light_species
stringclasses
67 values
antigen_species
stringclasses
937 values
authors
stringlengths
6
762
resolution
stringlengths
1
8
method
stringclasses
10 values
r_free
stringclasses
354 values
r_factor
stringclasses
342 values
scfv
bool
2 classes
engineered
bool
2 classes
heavy_subclass
stringclasses
14 values
light_subclass
stringclasses
35 values
light_ctype
stringclasses
3 values
affinity
float64
0
0
delta_g
float64
-16.91
-5.04
affinity_method
stringclasses
11 values
temperature
float64
4
37
pmid
stringclasses
157 values
7klc
H
L
0
A
protein
null
hiv-1 clade a bg505 gp120,hiv-1 clade a bg505 gp120
VIRAL PROTEIN/IMMUNE SYSTEM
10/29/20
Crystal structure of M4H2K1 Fab bound to HIV-1 BG505 gp120 core and to 17b Fab
MUS MUSCULUS; HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1
mus musculus
mus musculus
human immunodeficiency virus 1
Kumar, S., Wilson, I.A.
4.3
X-RAY DIFFRACTION
0.334
0.302
false
true
IGHV6
IGKV3
Kappa
null
null
null
null
null
2atk
A
B
0
C
protein
null
voltage-gated potassium channel
IMMUNE SYSTEM/ION TRANSPORT
08/25/05
Structure of a mutant KcsA K+ channel
MUS MUSCULUS; STREPTOMYCES LIVIDANS
mus musculus
mus musculus
streptomyces lividans
Cordero-Morales, J.F., Cuello, L.G., Zhao, Y., Jogini, V., Chakrapani, S., Roux, B., Perozo, E.
2.5
X-RAY DIFFRACTION
0.261
0.238
false
true
IGHV1
IGKV5
Kappa
null
null
null
null
null
7mwx
A
B
0
C
protein
null
core protein precursor ee2
VIRAL PROTEIN/IMMUNE SYSTEM
05/17/21
Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 with tamarin CD81
HEPACIVIRUS C; MUS MUSCULUS; SAGUINUS OEDIPUS
mus musculus
mus musculus
hepacivirus c
Kumar, A., Hossain, R.A., Yost, S.A., Bu, W., Wang, Y., Dearborn, A.D., Grakoui, A., Cohen, J.I., Marcotrigiano, J.
3.32
X-RAY DIFFRACTION
0.283
0.239
false
true
IGHV14
IGKV8
Kappa
null
null
null
null
null
5cez
H
L
0
G
protein
null
envelope glycoprotein gp160
VIRAL PROTEIN/IMMUNE SYSTEM
07/08/15
Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with an early putative precursor of the PGT121 family at 3.0 Angstrom
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1
Wilson, I.A., Garces, F.
3.031
X-RAY DIFFRACTION
0.266
0.233
false
true
IGHV4
unknown
unknown
null
null
null
null
null
1v7n
K
O
0
Z
protein
null
thrombopoietin
IMMUNE SYSTEM/CYTOKINE
12/18/03
Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab
MUS MUSCULUS; HOMO SAPIENS
mus musculus
mus musculus
homo sapiens
Feese, M.D., Tamada, T., Kato, Y., Maeda, Y., Hirose, M., Matsukura, Y., Shigematsu, H., Kato, T., Miyazaki, H., Kuroki, R.
3.3
X-RAY DIFFRACTION
0.305
0.167
false
true
IGHV6
IGKV4
Kappa
null
null
null
null
null
6z6v
H
null
0
E | F
protein | protein
NA | NA
complement c1q subcomponent subunit b | complement c1q subcomponent subunit c
IMMUNE SYSTEM
05/29/20
Globular head of C1q in complex with the nanobody C1qNb75
HOMO SAPIENS; LAMA GLAMA
lama glama
null
homo sapiens | homo sapiens
Laursen, N.S., Andersen, G.R.
2.19
X-RAY DIFFRACTION
0.227
0.178
false
true
IGHV1
null
null
null
null
null
null
null
7dc8
E
D
0
F
protein
null
interleukin-6 receptor subunit alpha
IMMUNE SYSTEM
10/23/20
Crystal structure of Switch Ab Fab and hIL6R in complex with ATP
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Kadono, S., Fukami, T.A., Kawauchi, H., Torizawa, T., Mimoto, F.
2.757
X-RAY DIFFRACTION
0.278
0.207
false
true
IGHV3
IGLV2
Lambda
null
null
null
null
null
6oz6
F
null
0
B
protein
null
phospho-n-acetylmuramoyl-pentapeptide-transferase
MEMBRANE PROTEIN/TRANSFERASE
05/15/19
Crystal structure of MraY bound to 3'-hydroxymureidomycin A
LAMA GLAMA; AQUIFEX AEOLICUS (STRAIN VF5)
lama glama
null
aquifex aeolicus (strain vf5)
Mashalidis, E.H., Lee, S.Y.
3.7
X-RAY DIFFRACTION
0.301
0.257
false
true
IGHV1
null
null
null
null
null
null
null
6rpj
B
null
0
A
protein
null
cytotoxic t-lymphocyte protein 4
IMMUNE SYSTEM
05/14/19
A Non-blocking anti-CTLA-4 Nanobody complexed with CTLA-4
HOMO SAPIENS; CAMELUS BACTRIANUS
camelus bactrianus
null
homo sapiens
Gao, H., Zhou, A., Zhang, F.
3.25
X-RAY DIFFRACTION
0.262
0.249
false
true
IGHV1
null
null
null
null
null
null
null
6dn0
A
B
0
null
null
null
null
IMMUNE SYSTEM
06/05/18
Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D.
HOMO SAPIENS
homo sapiens
homo sapiens
null
Langley, D.B., Roome, B., Christ, D.
2.0
X-RAY DIFFRACTION
0.234
0.205
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
2hvk
A
B
0
C
protein
null
voltage-gated potassium channel
Membrane Protein
07/28/06
crystal structure of the KcsA-Fab-TBA complex in high K+
STREPTOMYCES LIVIDANS; MUS MUSCULUS
mus musculus
mus musculus
streptomyces lividans
Zhou, Y.
1.9
X-RAY DIFFRACTION
0.245
0.228
false
false
IGHV1
IGKV5
Kappa
null
null
null
null
null
1igy
B
A
0
null
null
null
null
IMMUNOGLOBULIN
10/09/97
STRUCTURE OF IMMUNOGLOBULIN
MUS MUSCULUS
mus musculus
mus musculus
null
Harris, L.J., McPherson, A.
3.2
X-RAY DIFFRACTION
0.327
0.211
false
false
IGHV1
IGKV6
Kappa
null
null
null
null
null
4oly
H
L
0
G
protein
null
envelope glycoprotein gp160
VIRAL PROTEIN/IMMUNE SYSTEM
01/25/14
Crystal structure of antibody VRC07-G54R in complex with clade A/E 93TH057 HIV-1 gp120 core
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1
Kwon, Y.D., Kwong, P.D.
2.351
X-RAY DIFFRACTION
0.244
0.201
false
true
unknown
IGKV3
Kappa
null
null
null
null
null
6ikm
H
h
0
null
null
null
null
ANTIMICROBIAL PROTEIN
10/16/18
Crystal structure of SpuE-Spermidine in complex with ScFv5
PSEUDOMONAS AERUGINOSA; HOMO SAPIENS
pseudomonas aeruginosa
homo sapiens
null
Wu, D., Sun, X.
3.398
X-RAY DIFFRACTION
0.268
0.228
true
true
unknown
unknown
unknown
null
null
null
null
null
4odx
H
B
0
X
protein
null
4e10 epitope scaffold t117
IMMUNE SYSTEM
01/10/14
4E10 germline encoded precursor no.7 in complex with epitope scaffold T117
HOMO SAPIENS; ARTIFICIAL GENE
homo sapiens
homo sapiens
artificial gene
Finton, K.A.K.
3.1
X-RAY DIFFRACTION
0.304
0.280
false
true
IGHV1
IGKV3
Kappa
0
-11.850005
SPR
null
TBD
6iyn
A
null
8
null
null
null
null
AFLATOXIN B1-BINDING PROTEIN
12/17/18
Solution structure of camelid nanobody Nb26 against aflatoxin B1
VICUGNA PACOS
vicugna pacos
null
null
Nie, Y., He, T., Zhu, J., Li, S.L., Hu, R., Yang, Y.H.
NOT
SOLUTION NMR
null
null
false
true
IGHV1
null
null
null
null
null
null
null
6d0x
A
B
0
C
peptide
null
nanp3
IMMUNE SYSTEM
04/11/18
Crystal structure of chimeric H.2140 / K.1210 Fab in complex with circumsporozoite protein NANP3
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
plasmodium falciparum
Scally, S.W., Bosch, A., Imkeller, K., Wardemann, H., Julien, J.P.
1.849
X-RAY DIFFRACTION
0.209
0.179
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
6i8g
B
null
0
A
protein
null
protein eds1l
IMMUNE SYSTEM
11/20/18
Structure of the plant immune signaling node EDS1 (enhanced disease susceptibility 1) in complex with nanobody ENB73
ARABIDOPSIS THALIANA; LAMA GLAMA
lama glama
null
arabidopsis thaliana
Niefind, K., Voss, M., Toelzer, C.
2.344
X-RAY DIFFRACTION
0.222
0.194
false
true
IGHV1
null
null
null
null
null
null
null
1hcv
A
null
0
null
null
null
null
IMMUNOGLOBULIN
07/13/96
LLAMA HEAVY CHAIN VARIABLE DOMAIN AGAINST ALPHA SUBUNIT OF HCG (HUMAN CHORIONIC GONADOTROPIN)
LAMA GLAMA
lama glama
null
null
Spinelli, S., Cambillau, C., Tegoni, M.
1.85
X-RAY DIFFRACTION
0.218
0.171
false
true
unknown
unknown
unknown
null
null
null
null
null
6ww2
H
L
0
R
protein
null
frizzled-5,soluble cytochrome b562
MEMBRANE PROTEIN
05/07/20
Structure of human Frizzled5 by fiducial-assisted cryo-EM
HOMO SAPIENS; SYNTHETIC CONSTRUCT; ESCHERICHIA COLI
homo sapiens
homo sapiens
homo sapiens, escherichia coli
Tsutsumi, N., Jude, K.M., Gati, C., Garcia, K.C.
3.7
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
6olp
G
I
0
D | C | B
protein | protein | protein
NA | NA | NA
envelope glycoprotein gp41 | envelope glycoprotein gp120 | envelope glycoprotein gp41
Viral Protein/IMMUNE SYSTEM
04/16/19
Full length HIV-1 Env AMC011 in complex with PGT151 Fab
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1 | human immunodeficiency virus 1 | human immunodeficiency virus 1
Rantalainen, K., Cottrell, C.A.
4.2
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV2
Kappa
null
null
null
null
null
1rzi
H
G
0
null
null
null
null
IMMUNE SYSTEM
12/24/03
Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab
HOMO SAPIENS
homo sapiens
homo sapiens
null
Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
2.9
X-RAY DIFFRACTION
0.321
0.233
false
true
IGHV1
IGKV1
Kappa
null
null
null
null
null
6a78
I
M
0
B
protein
null
roundabout homolog 1
IMMUNE SYSTEM
07/02/18
Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the scFv fragment of murine monoclonal antibody B5209B
HOMO SAPIENS; MUS MUSCULUS
mus musculus
mus musculus
homo sapiens
Mizohata, E., Nakayama, T., Kado, Y., Inoue, T.
2.1
X-RAY DIFFRACTION
0.285
0.239
false
true
IGHV5
IGKV12
Kappa
null
null
null
null
null
1mnu
H
L
0
null
null
null
null
IMMUNE SYSTEM
04/30/99
UNLIGANDED BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
MUS MUSCULUS
mus musculus
mus musculus
null
Van Den Elsen, J., Vandeputte-Rutten, L., Kroon, J., Gros, P.
2.5
X-RAY DIFFRACTION
0.270
0.231
false
false
IGHV1
IGKV1
Kappa
null
null
null
null
null
7nvo
N
null
0
E
protein
null
t-complex protein 1 subunit epsilon
CHAPERONE
03/15/21
Human TRiC complex in open state with nanobody bound
HOMO SAPIENS; LAMA GLAMA
lama glama
null
homo sapiens
Kelly, J.J., Chi, G., Bulawa, C., Paavilainen, V.O., Bountra, C., Huiskonen, J.T., Yue, W.
3.5
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
2omn
null
B
0
null
null
null
null
Immune system
01/22/07
Bence Jones KWR Protein- Immunoglobulin Light Chain Dimer, P4(3)2(1)2 Crystal Form
HOMO SAPIENS
null
homo sapiens
null
Makino, D.L., Larson, S.B., McPherson, A.
2.2
X-RAY DIFFRACTION
0.283
0.226
false
false
null
IGLV2
Lambda
null
null
null
null
null
5mv4
O
P
0
Q
peptide
null
synthetic peptide containing the citrullinated collagentype ii epitope cii616-639,collagen alpha-1(ii) chain,synthetic peptide containing the citrullinated collagen type ii epitope cii616- 639
IMMUNE SYSTEM
01/15/17
ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23)
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
mus musculus
Dobritzsch, D., Holmdahl, R., Ge, C.
2.9
X-RAY DIFFRACTION
0.247
0.232
false
false
IGHV6
IGKV3
Kappa
null
null
null
null
null
2fx8
J
N
0
R
peptide
null
fragment of hiv glycoprotein (gp41)
IMMUNE SYSTEM
02/03/06
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with an aib-induced peptide encompassing the 4e10 epitope on gp41
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
null
Cardoso, R.M.F., Brunel, F.M., Ferguson, S., Burton, D.R., Dawson, P.E., Wilson, I.A.
2.2
X-RAY DIFFRACTION
0.283
0.235
false
true
IGHV1
IGKV3
Kappa
0
-8.89
SPR
null
17125793
7x6o
J
L
0
H | F
protein | protein
NA | NA
hemagglutinin | hemagglutinin
VIRAL PROTEIN
03/07/22
Cryo-EM structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 28-12
INFLUENZA A VIRUS; HOMO SAPIENS
homo sapiens
homo sapiens
influenza a virus | influenza a virus
Cong, Y., Liu, C.X.
3.5
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
5cp7
F
G
0
null
null
null
null
IMMUNE SYSTEM
07/21/15
Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody against Sulfonamides
MUS MUSCULUS
mus musculus
mus musculus
null
Wang, Z., Shen, J., Li, C., Li, Y., Wen, K., Yu, X., Zhang, X.
3.01
X-RAY DIFFRACTION
0.302
0.260
false
false
IGHV3
IGKV1
Kappa
null
null
null
null
null
6o26
A
B
0
C
peptide
null
circumsporozoite protein
IMMUNE SYSTEM
02/22/19
Crystal structure of 3246 Fab in complex with circumsporozoite protein NANA
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
plasmodium falciparum
Scally, S.W., Bosch, A., Castro, K., Murugan, R., Wardemann, H., Julien, J.P.
1.8
X-RAY DIFFRACTION
0.207
0.163
false
true
IGHV3
IGKV3
Kappa
null
null
null
null
null
3vga
C
B
0
A
protein
null
adenosine receptor a2a
SIGNALING PROTEIN
08/04/11
Crystal structure of human adenosine A2A receptor with an allosteric inverse-agonist antibody at 3.1 A resolution
HOMO SAPIENS; MUS MUSCULUS
mus musculus
mus musculus
homo sapiens
Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N., Cameron, A.D., Kobayashi, T., Hamakubo, T., Iwata, S., Murata, T.
3.1
X-RAY DIFFRACTION
0.263
0.196
false
false
IGHV1
IGKV12
Kappa
null
null
null
null
null
1mcs
null
A
0
P
peptide
null
peptide n-acetyl-l-gln-d-phe-l-his-d-pro-oh
IMMUNOGLOBULIN
02/25/93
PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
HOMO SAPIENS
null
homo sapiens
null
Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W.
2.7
X-RAY DIFFRACTION
unknown
unknown
false
true
null
IGLV2
Lambda
null
null
null
null
null
2kqm
null
A
3
null
null
null
null
IMMUNE SYSTEM
11/11/09
Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain
HOMO SAPIENS
null
homo sapiens
null
Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M.
NOT
SOLUTION NMR
null
null
false
true
null
IGKV1
Kappa
null
null
null
null
null
7rso
I
K
0
D
protein
null
amc016 gp120
VIRAL PROTEIN/IMMUNE SYSTEM
08/11/21
AMC016 SOSIP.v4.2 in complex with PGV04 Fab
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1
Bader, D.L.V., Cottrell, C.A., Ward, A.B.
4.1
ELECTRON MICROSCOPY
null
null
false
true
unknown
unknown
unknown
null
null
null
null
null
6bzu
G
H
0
L
peptide
null
e2 as412 peptide
IMMUNE SYSTEM
12/26/17
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 19B3
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
hepatitis c virus
Tzarum, N., Alemn, F., Kong, L., Wilson, I.A., Law, M.
2.7
X-RAY DIFFRACTION
0.290
0.265
false
true
IGHV3
IGKV3
Kappa
null
null
null
null
null
6pe9
E
F
0
U | I
protein | protein
NA | NA
tumor necrosis factor receptor superfamily member 5 | tumor necrosis factor receptor superfamily member 5
IMMUNE SYSTEM
06/20/19
Crystal Structure of CD40 complexed to FAB516
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens | homo sapiens
Argiriadi, M.A.
3.13
X-RAY DIFFRACTION
0.255
0.216
false
true
IGHV3
IGKV4
Kappa
null
null
null
null
null
1bbj
B
A
0
null
null
null
null
IMMUNOGLOBULIN
04/30/92
CRYSTAL STRUCTURE OF A CHIMERIC FAB' FRAGMENT OF AN ANTIBODY BINDING TUMOUR CELLS
HOMO SAPIENS
null
homo sapiens
null
Brady, R.L., Hubbard, R.E., Todd, R.J.
3.1
X-RAY DIFFRACTION
unknown
unknown
false
true
unknown
unknown
unknown
null
null
null
null
null
6niu
I
J
0
A
protein
null
envelope protein e
Viral protein/IMMUNE SYSTEM
12/31/18
Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 in complex with ZIKV E glycoprotein
HOMO SAPIENS; ZIKA VIRUS (ISOLATE ZIKV/HUMAN/FRENCH POLYNESIA/10087PF/2013)
homo sapiens
homo sapiens
zika virus (isolate zikv/human/frenchpolynesia/10087pf/2013)
Sankhala, R.S., Dussupt, V., Donofrio, G., Choe, M., Modjarrad, K., Michael, N.L., Krebs, S.J., Joyce, M.G.
4.303
X-RAY DIFFRACTION
0.359
0.264
false
true
IGHV4
IGLV1
Lambda
null
null
null
null
null
7ew0
E
e
0
A | B
protein | protein
NA | NA
guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1
MEMBRANE PROTEIN
05/24/21
Cryo-EM structure of ozanimod -bound Sphingosine-1-phosphate receptor 1 in complex with Gi protein
HOMO SAPIENS; MUS MUSCULUS
mus musculus
null
homo sapiens | homo sapiens
Yuan, Y., Jia, G.W., Su, Z.M., Shao, Z.H.
3.42
ELECTRON MICROSCOPY
null
null
true
true
unknown
unknown
unknown
null
null
null
null
null
1p7k
B
A
0
null
null
null
null
IMMUNE SYSTEM
05/02/03
Crystal structure of an anti-ssDNA antigen-binding fragment (Fab) bound to 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid (HEPES)
MUS MUSCULUS
mus musculus
mus musculus
null
Schuermann, J.P., Henzl, M.T., Deutscher, S.L., Tanner, J.J.
1.75
X-RAY DIFFRACTION
0.230
0.197
false
true
IGHV1
IGKV12
Kappa
null
null
null
null
null
7pgb
m
n
0
l
protein
null
unknown
MEMBRANE PROTEIN
08/13/21
NaV_Ae1/Sp1CTD_pore-SAT09 complex
HOMO SAPIENS; ALKALILIMNICOLA EHRLICHII (STRAIN ATCC BAA-1101 / DSM 17681 / MLHE-1); RUEGERIA POMEROYI (STRAIN ATCC 700808 / DSM 15171 / DSS-3)
homo sapiens
homo sapiens
alkalilimnicola ehrlichii (strain atcc baa-1101/ dsm 17681 / mlhe-1), ruegeria pomeroyi (strain atcc 700808 / dsm 15171 / dss-3)
Lolicato, M., Arrigoni, C.
3.6
X-RAY DIFFRACTION
0.232
0.207
false
false
IGHV3
IGKV1
Kappa
null
null
null
null
null
6o3u
B
A
0
F
Hapten
44E
(2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate
IMMUNE SYSTEM
02/27/19
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with 06:0 PA
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Irimia, A., Wilson, I.A.
3.105
X-RAY DIFFRACTION
0.228
0.186
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
4g6a
C
D
0
B
peptide
null
e2 peptide
IMMUNE SYSTEM
07/18/12
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody AP33
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
hepatitis c virus
Kong, L., Wilson, I.A., Law, M.
2.501
X-RAY DIFFRACTION
0.220
0.178
false
true
IGHV3
IGKV3
Kappa
null
null
null
null
null
6mts
H
L
0
null
null
null
null
IMMUNE SYSTEM
10/21/18
Crystal structure of VRC43.03 Fab
HOMO SAPIENS
homo sapiens
homo sapiens
null
Kwon, Y.D., Druz, A., Law, W.H., Peng, D., Doria-Rose, N.A., Kwong, P.D.
2.437
X-RAY DIFFRACTION
0.268
0.242
false
true
IGHV4
IGLV7
Lambda
null
null
null
null
null
7l02
M
K
0
A
protein
null
spike glycoprotein
VIRAL PROTEIN/IMMUNE SYSTEM
12/10/20
Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to one copy of domain-swapped antibody 2G12
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Manne, K., Henderson, R., Acharya, P.
3.2
ELECTRON MICROSCOPY
null
null
false
true
unknown
IGKV1
Kappa
null
null
null
null
null
2w60
A
B
0
null
null
null
null
IMMUNE SYSTEM
12/16/08
Anti citrullinated Collagen type 2 antibody acc4
MUS MUSCULUS
mus musculus
mus musculus
null
Uysal, H., Bockermann, R., Nandakumar, K.S., Sehnert, B., Bajtner, E., Engstrom, A., Serre, G., Burkhardt, H., Thunnissen, M.M.G.M., Holmdahl, R.
1.5
X-RAY DIFFRACTION
0.220
0.169
false
false
IGHV9
IGKV1
Kappa
null
null
null
null
null
3b5g
null
A
0
null
null
null
null
IMMUNE SYSTEM
10/25/07
Crystal Structure of the Unstable and Highly Fibrillogenic PRO7SER Mutant of the Recombinant Variable Domain 6AJL2
HOMO SAPIENS
null
homo sapiens
null
Hernandez-Santoyo, A., Rodriguez-Romero, A.
1.9
X-RAY DIFFRACTION
0.210
0.164
false
true
null
IGLV6
Lambda
null
null
null
null
null
7p5w
I
null
0
C
protein
null
volume-regulated anion channel subunit lrrc8a
MEMBRANE PROTEIN
07/15/21
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb2
MUS MUSCULUS; SYNTHETIC CONSTRUCT
synthetic construct
null
mus musculus
Deneka, D., Rutz, S., Sawicka, M.
3.5
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
4nc1
E
null
0
A
protein
null
cell wall-binding repeat protein
IMMUNE SYSTEM
10/23/13
Crystal Structure of TcdA-A2 Bound to A20.1 VHH and A26.8 VHH
CLOSTRIDIUM DIFFICILE; LAMA GLAMA
lama glama
null
clostridium difficile
Murase, T., Eugenio, L., Schorr, M., Hussack, G., Tanha, J., Kitova, E.N., Klassen, J.S., Ng, K.K.S.
2.61
X-RAY DIFFRACTION
0.252
0.202
false
true
IGHV1
null
null
null
null
null
null
null
7a3q
H
L
0
A
protein
null
envelope protein e
VIRAL PROTEIN
08/18/20
Crystal structure of dengue 4 virus envelope glycoprotein in complex with the scFv fragment of the broadly neutralizing human antibody EDE1 C10
DENGUE VIRUS 4; HOMO SAPIENS
homo sapiens
homo sapiens
dengue virus 4
Sharma, A., Vaney, M.C., Guardado-Calvo, P., Duquerroy, S., Rouvinski, A., Rey, F.A.
2.7
X-RAY DIFFRACTION
0.239
0.216
false
true
IGHV1
IGLV2
Lambda
null
null
null
null
null
4onf
H
L
0
P
peptide
null
amyloid beta a4 protein
IMMUNE SYSTEM
01/28/14
Fab fragment of 3D6 in complex with amyloid beta 1-7
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
homo sapiens
Feinberg, H., Saldanha, J.W., Diep, L., Goel, A., Widom, A., Veldman, G.M., Weis, W.I., Schenk, D., Basi, G.S.
2.0
X-RAY DIFFRACTION
0.203
0.158
false
true
IGHV5
IGKV1
Kappa
0
-12.170174
Unknown
null
TBD
6tcp
F
E
0
null
null
null
null
IMMUNE SYSTEM
11/06/19
Crystal structure of the omalizumab Fab Leu158Pro light chain mutant - crystal form II
HOMO SAPIENS
homo sapiens
homo sapiens
null
Mitropoulou, A.N., Ceska, T., Beavil, A.J., Henry, A.J., McDonnell, J.M., Sutton, B.J., Davies, A.M.
2.5
X-RAY DIFFRACTION
0.239
0.212
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
5u5m
B
A
0
C | E
protein | protein
NA | NA
immunoglobulin g binding protein a | protein l
IMMUNE SYSTEM
12/06/16
CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-MEDITOPE
HOMO SAPIENS; FINEGOLDIA MAGNA; STAPHYLOCOCCUS AUREUS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
staphylococcus aureus | finegoldia magna
Williams, J.C., Bzymek, K.P., Pucket, J., Avery, K.A., Ma, Y., Xie, J., Zer, C., Horne, D.
1.88
X-RAY DIFFRACTION
0.197
0.161
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
3dro
B
A
0
P
peptide
null
elleldkwaslwn gp41 peptide
IMMUNE SYSTEM
07/11/08
Crystal structure of the HIV-1 Cross Neutralizing Antibody 2F5 in complex with gp41 Peptide ELLELDKWASLWN grown in ammonium sulfate
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
null
Julien, J.-P., Bryson, S., Pai, E.F.
3.9
X-RAY DIFFRACTION
0.263
0.222
false
true
IGHV2
IGKV1
Kappa
null
null
null
null
null
6mhr
A
B
0
C
protein
null
tumor necrosis factor receptor superfamily member 9
IMMUNE SYSTEM
09/18/18
Structure of the human 4-1BB / Urelumab Fab complex
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Kimberlin, C.R., Chin, S.M., Roe-Zurz, Z., Xu, A., Yang, Y.
2.8
X-RAY DIFFRACTION
0.222
0.200
false
true
IGHV4
IGKV3
Kappa
0
-10.446805
SPR
null
TBD
3tnm
A
B
0
null
null
null
null
IMMUNE SYSTEM
09/01/11
Crystal structure of A32 Fab, an ADCC mediating anti-HIV-1 antibody
HOMO SAPIENS
homo sapiens
homo sapiens
null
Wu, X., Pazgier, M.
1.85
X-RAY DIFFRACTION
0.232
0.187
false
true
IGHV4
IGLV2
Lambda
null
null
null
null
null
6qpg
N
null
0
D | E
protein | protein
NA | NA
polymerase acidic protein | rna-directed rna polymerase catalytic subunit
RNA BINDING PROTEIN
02/13/19
Influenza A virus Polymerase Heterotrimer A/nt/60/1968(H3N2) in complex with Nanobody NB8205
INFLUENZA A VIRUS (STRAIN A/NORTHERN TERRITORY/60/1968 H3N2); CAMELIDAE
camelidae
null
influenza a virus (strain a/northernterritory/60/1968 h3n2) | influenza a virus (strain a/northernterritory/60/1968 h3n2)
Fan, H.T., Keown, J.R., Fodor, E., Grimes, J.M.
3.34
X-RAY DIFFRACTION
0.305
0.251
false
true
IGHV3
null
null
null
null
null
null
null
2i60
H
L
0
G
protein
null
exterior membrane glycoprotein(gp120)
VIRAL PROTEIN/IMMUNE SYSTEM
08/26/06
Crystal structure of [Phe23]M47, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 GP120 envelope glycoprotein and anti-HIV-1 antibody 17B
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
human immunodeficiency virus 1
Huang, C.-C., Kwong, P.D.
2.4
X-RAY DIFFRACTION
0.281
0.215
false
true
IGHV1
IGKV3
Kappa
0
-11.193371
SPR
null
TBD
6vep
O
P
0
Q
protein
null
insulin receptor subunit alpha
HORMONE RECEPTOR/HORMONE/IMMUNE SYSTEM
06/03/20
Human insulin in complex with the human insulin microreceptor in turn in complex with Fv 83-7
HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
homo sapiens
Lawrence, M.C., Menting, J.G.T.
2.9
X-RAY DIFFRACTION
0.225
0.193
false
true
IGHV2
IGKV8
Kappa
null
null
null
null
null
3mlu
H
L
0
P
peptide
null
hiv-1 gp120 third variable region (v3) crown
IMMUNE SYSTEM
04/18/10
Crystal structure of anti-HIV-1 V3 Fab 2557 in complex with a ZAM18 V3 peptide
HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1
homo sapiens
homo sapiens
human immunodeficiency virus 1
Kong, X.-P.
2.77
X-RAY DIFFRACTION
0.310
0.196
false
false
IGHV5
IGLV3
Lambda
null
null
null
null
null
5tr1
H
L
0
A
protein
null
chloride channel protein
TRANSPORT PROTEIN
10/25/16
Cryo-electron microscopy structure of a bovine CLC-K chloride channel, alternate (class 2) conformation
BOS TAURUS; MUS MUSCULUS
mus musculus
mus musculus
bos taurus
Park, E., MacKinnon, R.
3.95
ELECTRON MICROSCOPY
null
null
false
false
IGHV3
IGKV6
Kappa
null
null
null
null
null
1ken
T
U
0
C | E
protein | protein
NA | NA
hemagglutinin ha1 | hemagglutinin ha1
Viral protein/Immune system
11/16/01
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH AN ANTIBODY THAT PREVENTS THE HEMAGGLUTININ LOW PH FUSOGENIC TRANSITION
INFLUENZA A VIRUS (A/X-31(H3N2)); MUS MUSCULUS
mus musculus
mus musculus
influenza a virus (a/x-31(h3n2)) | influenza a virus (a/x-31(h3n2))
Barbey-Martin, C., Gigant, B., Bizebard, T., Calder, L.J., Wharto, S.A., Skehel, J.J., Knossow, M.
3.5
X-RAY DIFFRACTION
0.323
0.255
false
false
IGHV3
IGKV4
Kappa
null
null
null
null
null
1u8j
B
A
0
C
peptide
null
gp41 peptide
IMMUNE SYSTEM
08/06/04
Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELDKWAG
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
human immunodeficiency virus 1
Bryson, S., Julien, J.-P., Hynes, R.C., Pai, E.F.
2.24
X-RAY DIFFRACTION
0.239
0.229
false
false
IGHV2
IGKV1
Kappa
null
null
null
null
null
6uum
H
F
0
null
null
null
null
IMMUNE SYSTEM
10/30/19
Crystal structure of antibody 438-B11 DSS mutant (Cys98A-Cys100aA)
HOMO SAPIENS
homo sapiens
homo sapiens
null
Kumar, S., Wilson, I.A.
2.1
X-RAY DIFFRACTION
0.269
0.229
false
true
unknown
IGKV3
Kappa
null
null
null
null
null
1tpx
B
C
0
A
protein
null
major prion protein
UNKNOWN FUNCTION
06/16/04
Ovine recombinant PrP(114-234), ARQ variant in complex with the Fab of the VRQ14 antibody
OVIS ARIES; MUS MUSCULUS
mus musculus
mus musculus
ovis aries
Eghiaian, F., Grosclaude, J., Lesceu, S., Debey, P., Doublet, B., Treguer, E., Rezaei, H., Knossow, M.
2.56
X-RAY DIFFRACTION
0.282
0.220
false
false
IGHV9
IGKV1
Kappa
null
null
null
null
null
5dd3
H
L
0
null
null
null
null
IMMUNE SYSTEM
08/24/15
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
MACACA MULATTA
macaca mulatta
macaca mulatta
null
Nicely, N.I., Pemble IV, C.W., Haynes, B.F.
1.797
X-RAY DIFFRACTION
0.248
0.199
false
true
IGHV4
IGKV1
Kappa
null
null
null
null
null
2mmx
null
A
7
null
null
null
null
IMMUNE SYSTEM
03/20/14
NMR study of 6aJL2
HOMO SAPIENS
null
homo sapiens
null
Amero, C., Maya-Martinez, R.C., Gil-Rodriguez, P.C.
NOT
SOLUTION NMR
null
null
false
true
null
IGLV6
Lambda
null
null
null
null
null
4f15
H
I
0
G
protein
null
hemagglutinin
IMMUNE SYSTEM
05/06/12
Molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses
INFLUENZA A VIRUS; MUS MUSCULUS
mus musculus
mus musculus
influenza a virus
Kim, K.H., Cho, K.J., Lee, J.H., Park, Y.H., Khan, T.G., Lee, J.Y., Kang, S.H., Alam, I.
2.81
X-RAY DIFFRACTION
0.289
0.233
false
false
IGHV3
IGKV7
Kappa
null
null
null
null
null
6myy
D
C
0
B
protein
null
426c ds-sosip d3
VIRAL PROTEIN/IMMUNE SYSTEM
11/02/18
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1
Borst, A.J., Weidle, C.E., Gray, M.D., Frenz, B., Snijder, J., Joyce, M.G., Georgiev, I.S., Stewart-Jones, G.B.E., Kwong, P.D., McGuire, A.T., DiMaio, F., Stamatatos, L., Pancera, M., Veesler, D.
3.8
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
5mwn
N
null
0
A
protein
null
type vi secretion protein
TRANSPORT PROTEIN
01/18/17
Structure of the EAEC T6SS component TssK N-terminal domain in complex with llama nanobodies nbK18 and nbK27
LAMA GLAMA; ESCHERICHIA COLI
null
null
escherichia coli
Cambillau, C., Nguyen, V.S., Spinelli, S., Legrand, P.
2.2
X-RAY DIFFRACTION
0.220
0.199
false
true
IGHV1
null
null
null
null
null
null
null
3jbq
H
L
0
F
protein
null
phosphodiesterase 5/6 chimera catalytic domain
HYDROLASE/IMMUNE SYSTEM
09/17/15
Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6
MUS MUSCULUS; BOS TAURUS
mus musculus
mus musculus
bos taurus
Zhang, Z., He, F., Constantine, R., Baker, M.L., Baehr, W., Schmid, M.F., Wensel, T.G., Agosto, M.A.
11
ELECTRON MICROSCOPY
null
null
false
false
IGHV14
IGKV6
Kappa
null
null
null
null
null
3ijh
B
A
0
B
carbohydrate
KO2
PROP-2-EN-1-YL D-GLYCERO-ALPHA-D-TALO-OCT-2-ULOPYRANOSIDONIC ACID
IMMUNE SYSTEM
08/04/09
Structure of S67-27 in Complex with Ko
MUS MUSCULUS
mus musculus
mus musculus
mus musculus
Brooks, C.L., Blackler, R.J., Evans, S.V.
2.1
X-RAY DIFFRACTION
0.254
0.213
false
false
IGHV7
IGKV8
Kappa
0.0001
-5.456976
Unknown
null
TBD
1mak
null
A
8
null
null
null
null
IMMUNOGLOBULIN
09/16/93
SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN
MUS MUSCULUS
null
mus musculus
null
Constantine, K.L., Friedrichs, M.S., Metzler, W.J., Wittekind, M., Hensley, P., Mueller, L.
NOT
SOLUTION NMR
null
null
false
true
unknown
unknown
unknown
null
null
null
null
null
7vsu
D
C
0
null
null
null
null
BIOSYNTHETIC PROTEIN
10/27/21
Crystal structure of Fab fragment of anti-mesothelin antibody
HOMO SAPIENS
homo sapiens
homo sapiens
null
Yang, Z., Ying, T.
3.1
X-RAY DIFFRACTION
0.249
0.215
false
true
IGHV4
IGKV1
Kappa
null
null
null
null
null
7r8l
H
L
0
E
protein
null
spike protein s1
VIRAL PROTEIN/IMMUNE SYSTEM
06/26/21
Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody C099 and CR3022
HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Barnes, C.O., Bjorkman, P.J.
2.6
X-RAY DIFFRACTION
0.229
0.180
false
true
IGHV3
IGKV3
Kappa
null
null
null
null
null
3cdf
null
C
0
null
null
null
null
IMMUNE SYSTEM
02/26/08
kI O18/O8 Y87H immunoglobulin light chain variable domain
HOMO SAPIENS
null
homo sapiens
null
Baden, E.M., Randles, E.G., Thompson, J.R., Ramirez-Alvarado, M.
1.53
X-RAY DIFFRACTION
0.231
0.189
false
true
null
IGKV1
Kappa
null
null
null
null
null
5xcu
D
E
0
F
peptide
null
ha peptide
IMMUNE SYSTEM
03/23/17
Crystal structure of 12CA5 Fv-clasp fragment with its antigen peptide
MUS MUSCULUS; HOMO SAPIENS; SYNTHETIC CONSTRUCT
mus musculus, homo sapiens
mus musculus, homo sapiens
homo sapiens
Arimori, T., Takagi, J.
2.454
X-RAY DIFFRACTION
0.247
0.199
false
true
IGHV5
IGKV8
Kappa
null
null
null
null
null
7ocy
C
null
0
A | B
protein | protein
NA | NA
abc transporter atp-binding protein | abc transporter atp-binding protein
MEMBRANE PROTEIN
04/28/21
Enterococcus faecalis EfrCD in complex with a nanobody
ENTEROCOCCUS FAECALIS; VICUGNA PACOS
vicugna pacos
null
enterococcus faecalis | enterococcus faecalis
Ehrenbolger, K., Hutter, C.A.J., Meier, G., Seeger, M.A., Barandun, J.
4.25
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
4uif
K
L
0
C
protein
null
dengue virus serotype 2 strain pvp94 07 - envelopeprotein
null
03/30/15
Cryo-EM structure of Dengue virus serotype 2 in complex with antigen- binding fragments of human antibody 2D22
DENGUE VIRUS 2; HOMO SAPIENS
homo sapiens
homo sapiens
dengue virus 2
Fibriansah, G., Ibarra, K.D., Ng, T.-S., Smith, S.A., Tan, J.L., Lim, X.-N., Ooi, J.S.G., Kostyuchenko, V.A., Wang, J., de Silva, A.M., Harris, E., Crowe Junior, J.E., Lok, S.-M.
6.5
ELECTRON MICROSCOPY
null
null
false
false
IGHV1
IGLV1
Lambda
null
null
null
null
null
4c2i
H
L
0
C
protein
null
envelope protein
VIRUS
08/18/13
Cryo-EM structure of Dengue virus serotype 1 complexed with Fab fragments of human antibody 1F4
HOMO SAPIENS; DENGUE VIRUS 1
homo sapiens
homo sapiens
dengue virus 1
Fibriansah, G., Tan, J.L., de Alwis, R., Smith, S.A., Ng, T.-S., Kostyuchenko, V.A., Ibarra, K.D., Harris, E., de Silva, A., Crowe Junior, J.E., Lok, S.-M.
6.0
ELECTRON MICROSCOPY
null
null
false
false
IGHV3
IGLV1
Lambda
null
null
null
null
null
7x2f
E
null
0
A | B | D
protein | protein | protein
NA | NA | NA
guanine nucleotide-binding protein g(s) subunit alphaisoforms short, isoform gnas-2 of guanine nucleotide-binding protein g(s) subunit alpha isoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2
MEMBRANE PROTEIN
02/25/22
Cryo-EM structure of the dopamine and LY3154207-bound D1 dopamine receptor and mini-Gs complex
HOMO SAPIENS; SYNTHETIC CONSTRUCT
synthetic construct
null
homo sapiens | homo sapiens | homo sapiens
Teng, X., Zheng, S.
3
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
null
null
null
null
null
null
null
2c1o
H
L
0
null
null
null
null
IMMUNE SYSTEM
09/19/05
ENAIIHis Fab fragment in the free form
MUS MUSCULUS
mus musculus
mus musculus
null
Parkkinen, T., Nevanen, T., Koivula, A., Rouvinen, J.
2.75
X-RAY DIFFRACTION
0.3011
0.2184
false
true
IGHV1
IGKV1
Kappa
null
null
null
null
null
6xxn
F
null
0
null
null
null
null
ANTITUMOR PROTEIN
06/10/20
Crystal structure of NB7, a nanobody targeting prostate specific membrane antigen
CAMELUS DROMEDARIUS
camelus dromedarius
null
null
Shahar, A., Rosenfeld, L., Papo, N.
2.65
X-RAY DIFFRACTION
0.231
0.182
false
true
IGHV1
null
null
null
null
null
null
null
6sc6
B
null
0
A
protein
null
e3 ubiquitin-protein ligase rnf31
LIGASE
07/23/19
dAb3/HOIP-RBR apo structure
HOMO SAPIENS; SYNTHETIC CONSTRUCT
synthetic construct
null
homo sapiens
Tsai, Y.-C.I., House, D., Rittinger, K.
2.25
X-RAY DIFFRACTION
0.246
0.199
false
true
IGHV3
null
null
null
null
null
null
null
6wo3
H
L
0
E
protein
null
envelope glycoprotein e2
IMMUNE SYSTEM/Viral Protein
04/24/20
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody U1
RECOMBINANT HEPATITIS C VIRUS HK6A/JFH-1; HOMO SAPIENS
homo sapiens
homo sapiens
recombinant hepatitis c virus hk6a/jfh-1
Tzarum, N., Wilson, I.A., Law, M.
2.382
X-RAY DIFFRACTION
0.260
0.230
false
true
IGHV1
IGKV1
Kappa
null
null
null
null
null
6my4
A
B
0
null
null
null
null
IMMUNE SYSTEM
11/01/18
Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M,LC-S30bR]
HOMO SAPIENS
homo sapiens
homo sapiens
null
Shi, R., Picard, M.-E., Manenda, M.
1.69
X-RAY DIFFRACTION
0.230
0.189
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
1yef
H
L
0
L
Hapten
PNC
PARA-NITROBENZYL GLUTARYL GLYCINIC ACID
CATALYTIC ANTIBODY
05/29/97
STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH SUBSTRATE ANALOGUE
MUS MUSCULUS
mus musculus
mus musculus
mus musculus
Gigant, B., Knossow, M.
2.0
X-RAY DIFFRACTION
0.248
0.199
false
false
IGHV1
IGKV1
Kappa
null
null
null
null
null
2znx
B
b
0
Z
protein
null
lysozyme c
IMMUNE SYSTEM/HYDROLASE
05/02/08
5-Fluorotryptophan Incorporated ScFv10 Complexed to Hen Egg Lysozyme
MUS MUSCULUS; SYNTHETIC CONSTRUCT; GALLUS GALLUS
mus musculus, synthetic construct
null
gallus gallus
DeSantis, M.E., Acchione, M., Li, M., Walter, R.L., Wlodawer, A., Smith-Gill, S.
2.3
X-RAY DIFFRACTION
0.232
0.193
true
true
unknown
unknown
unknown
null
null
null
null
null
5gs1
I
i
0
null
null
null
null
IMMUNE SYSTEM
08/13/16
Crystal structure of homo-specific diabody
HOMO SAPIENS
homo sapiens
null
null
Kim, J.H., Song, D.H., Youn, S.J., Kim, J.W., Cho, G., Lee, H., Lee, J.O.
2.0
X-RAY DIFFRACTION
0.286
0.267
true
true
unknown
unknown
unknown
null
null
null
null
null
7v0v
A
null
0
null
null
null
null
IMMUNE SYSTEM
05/11/22
GFP Nanobody NMR Structure
SYNTHETIC CONSTRUCT
synthetic construct
null
null
Mueller, G.A.
NOT
SOLUTION NMR
null
null
false
true
IGHV1
null
null
null
null
null
null
null
7oan
F
null
0
A
protein
null
spike glycoprotein
ANTIVIRAL PROTEIN
04/19/21
Nanobody C5 bound to Spike
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; VICUGNA PACOS
vicugna pacos
null
severe acute respiratory syndrome coronavirus2
Naismith, J.H., Weckener, M.
3.0
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
3cfk
N
M
0
M
Hapten
B3P
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
IMMUNE SYSTEM
03/04/08
Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form
MUS MUSCULUS, HOMO SAPIENS
mus musculus, homo sapiens
mus musculus, homo sapiens
mus musculus, homo sapiens
Debler, E.W., Wilson, I.A.
2.6
X-RAY DIFFRACTION
0.244
0.221
false
true
IGHV4
IGLV1
Lambda
null
null
null
null
null
7qnb
N
null
0
E | D
protein | protein
NA | NA
gamma-aminobutyric acid receptor subunit beta-3 | gamma-aminobutyric acid receptor subunit beta-3
MEMBRANE PROTEIN
12/20/21
Cryo-EM structure of human full-length beta3gamma2 GABA(A)R in complex with GABA and nanobody Nb25
HOMO SAPIENS; LAMA GLAMA
lama glama
null
homo sapiens | homo sapiens
Sente, A., Desai, R., Naydenova, K., Malinauskas, T., Jounaidi, Y., Miehling, J., Zhou, X., Masiulis, S., Hardwick, S.W., Chirgadze, D.Y., Miller, K.W., Aricescu, A.R.
3.1
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
2p44
B
null
0
A
protein
null
ribonuclease pancreatic
HYDROLASE/IMMUNE SYSTEM
03/11/07
Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.8A resolution: SE5A-mono-1 crystal form with five se-met sites (M34, M51, F68M, M83, L86M) in vhh scaffold
CAMELUS DROMEDARIUS; BOS TAURUS
camelus dromedarius
null
bos taurus
Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.
1.8
X-RAY DIFFRACTION
0.238
0.193
false
true
IGHV1
null
null
0
-10.67
Other
30
18445622
7nd6
H
L
0
B
protein
null
spike glycoprotein
VIRAL PROTEIN/IMMUNE SYSTEM
01/30/21
EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-40 Fab
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Duyvesteyn, H.M.E., Zhao, Y., Ren, J., Stuart, D.
7.3
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
7mmo
A
B
0
C
protein
null
spike protein s1
IMMUNE SYSTEM/VIRAL PROTEIN
04/30/21
LY-CoV1404 neutralizing antibody against SARS-CoV-2
HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Hendle, J., Pustilnik, A., Sauder, J.M., Coleman, K.A., Boyles, J.S., Dickinson, C.D.
2.427
X-RAY DIFFRACTION
0.253
0.226
false
true
IGHV2
IGLV2
Lambda
null
null
null
null
null
1g9e
A
null
13
null
null
null
null
IMMUNE SYSTEM
11/23/00
SOLUTION STRUCTURE AND RELAXATION MEASUREMENTS OF AN ANTIGEN-FREE HEAVY CHAIN VARIABLE DOMAIN (VHH) FROM LLAMA
LAMA GLAMA
lama glama
null
null
Renisio, J.-G., Perez, J., Czisch, M., Guenneugues, M., Bornet, O., Frenken, L., Cambillau, C., Darbon, H.
NOT
SOLUTION NMR
null
null
false
true
IGHV1
null
null
null
null
null
null
null
7tpr
D
null
0
B
protein
null
spike glycoprotein
VIRAL PROTEIN/IMMUNE SYSTEM
01/25/22
Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; CAMELUS DROMEDARIUS
camelus dromedarius
null
severe acute respiratory syndrome coronavirus2
Butay, K.J., Zhu, J., Dandey, V.P., Hong, J., Kwon, H.J., Chen, C.Z., Duan, Z., Li, D., Ren, H., Liang, T., Martin, N., Esposito, D., Ortega-Rodriguez, U., Xu, M., Xie, H., Ho, M., Cachau, R., Borgnia, M.J.
2.39
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
4krm
B
null
0
A
protein
null
epidermal growth factor receptor
TRANSFERASE/IMMUNE SYSTEM
05/16/13
Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 3.5
LAMA GLAMA; HOMO SAPIENS
lama glama
null
homo sapiens
Ferguson, K.M., Schmitz, K.R.
2.655
X-RAY DIFFRACTION
0.244
0.208
false
true
IGHV1
null
null
null
null
null
null
null