pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
6cdp | A | B | 0 | C | peptide | null | hiv-1 fusion peptide 512-519 | IMMUNE SYSTEM | 02/08/18 | Vaccine-elicited HIV-1 neutralizing antibody vFP20.01 in complex with HIV-1 fusion peptide residue 512-519 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | human immunodeficiency virus 1 | Xu, K., Liu, K., Kwong, P.D. | 2.456 | X-RAY DIFFRACTION | 0.264 | 0.212 | false | true | IGHV1 | IGKV1 | Kappa | 0 | -11.985097 | Unknown | null | TBD |
4ocy | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/09/14 | Fab for methotrexate (unbound apo) | MUS MUSCULUS | mus musculus | mus musculus | null | Longenecker, K.L., Judge, R.A., Gayda, S., Manoj, S., Saldana, S., Ruan, Q., Swift, K., Tetin, S. | 2.79 | X-RAY DIFFRACTION | 0.206 | 0.182 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6wfy | H | L | 0 | P | peptide | null | npna4 peptide | IMMUNE SYSTEM | 04/04/20 | Crystal structure of Fab224 in complex with NPNA4 peptide from circumsporozoite protein | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Pholcharee, T., Oyen, D., Wilson, I.A. | 1.226 | X-RAY DIFFRACTION | 0.183 | 0.169 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
3fo9 | H | L | 0 | H | Hapten | DIK | 5-{[4-(5-METHYL-3-OXOHEX-4-EN-1-YL)PHENYL]AMINO}-5-OXOPENTANOIC ACID | IMMUNE SYSTEM | 12/29/08 | Crystal structure of aldolase antibody 33F12 Fab' in complex with hapten 1,3-diketone | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Zhu, X., Wilson, I.A. | 1.9 | X-RAY DIFFRACTION | 0.249 | 0.215 | false | true | IGHV6 | IGKV1 | Kappa | null | null | null | null | null |
1mlc | B | A | 0 | E | protein | null | hen egg white lysozyme | COMPLEX (ANTIBODY/ANTIGEN) | 03/10/95 | MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME COMPLEXED WITH LYSOZYME | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | gallus gallus | Braden, B.C., Souchon, H., Eisele, J.-L., Bentley, G.A., Bhat, T.N., Navaza, J., Poljak, R.J. | 2.5 | X-RAY DIFFRACTION | 0.282 | unknown | false | true | IGHV1 | IGKV5 | Kappa | 0 | -9.6 | SPR | 25 | 10229844 |
5tp3 | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 10/19/16 | Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4 | LAMA GLAMA | lama glama | null | null | Wrapp, D., Gilman, M.S.A., McLellan, J.S. | 1.874 | X-RAY DIFFRACTION | 0.208 | 0.170 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ada | C | D | 0 | A | protein | null | h(+)/cl(-) exchange transporter clca | TRANSPORT PROTEIN | 07/31/18 | Crystal structure of the E148D mutant CLC-ec1 in 200mM bromide | ESCHERICHIA COLI (STRAIN K12); MUS MUSCULUS | mus musculus | mus musculus | escherichia coli (strain k12) | Lim, H.-H., Park, K. | 3.153 | X-RAY DIFFRACTION | 0.290 | 0.231 | false | false | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
6yz7 | D | null | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 05/06/20 | H11-D4, SARS-CoV-2 RBD, CR3022 ternary complex | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Naismith, J.H., Ren, J., Zhou, D., Zhao, Y., Stuart, D.I. | 3.3 | X-RAY DIFFRACTION | 0.269 | 0.238 | false | true | IGHV1 | null | null | null | null | null | null | null |
6mhg | H | L | 0 | E | protein | null | circumsporozoite protein | IMMUNE SYSTEM | 09/17/18 | Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts | PLASMODIUM FALCIPARUM; HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium falciparum | Cottrell, C.A., Torres, J.L., Ward, A.B. | 3.57 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7te8 | D | null | 0 | D | Hapten | P0T | cannabidiol | BIOSYNTHETIC PROTEIN | 01/04/22 | CA14-CBD-DB21 ternary complex | ARTIFICIAL SEQUENCES | artificial sequences | null | artificial sequences | Cao, S., Zheng, N. | 1.998 | X-RAY DIFFRACTION | 0.211 | 0.180 | false | true | IGHV1 | null | null | null | null | null | null | null |
1cic | D | C | 0 | null | null | null | null | IMMUNOGLOBULIN | 03/31/99 | IDIOTOPE-ANTI-IDIOTOPE FAB-FAB COMPLEX; D1.3-E225 | MUS MUSCULUS | mus musculus | mus musculus | null | Bentley, G.A. | 2.5 | X-RAY DIFFRACTION | unknown | 0.179 | false | false | IGHV2 | IGKV12 | Kappa | null | null | null | null | null |
6o3b | G | E | 0 | H | protein | null | frizzled-7 | SIGNALING PROTEIN | 02/26/19 | Crystal structure of Frizzled 7 CRD in complex with F6 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Raman, S., Beilschmidt, M., Fransson, J., Julien, J.P. | 2.5 | X-RAY DIFFRACTION | 0.283 | 0.248 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4rir | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 10/07/14 | Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk | HOMO SAPIENS | homo sapiens | homo sapiens | null | Nicely, N.I., Wiehe, K., Kepler, T.B., Jaeger, F.H., Dennison, S.M., Liao, H.-X., Alam, S.M., Hwang, K.-K., Bonsignori, M., Rerks-Ngarm, S., Nitayaphan, S., Pitisuttithum, P., Kaewkungwal, J., Robb, M.L., O'Connell, R.J., Michael, N.L., Kim, J.H., Haynes, B.F. | 2.5 | X-RAY DIFFRACTION | 0.289 | 0.220 | false | true | IGHV5 | IGLV6 | Lambda | null | null | null | null | null |
5tqq | H | L | 0 | A | protein | null | chloride channel protein | TRANSPORT PROTEIN | 10/24/16 | Cryo-electron microscopy structure of a bovine CLC-K chloride channel, main (class 1) conformation | MUS MUSCULUS; BOS TAURUS | mus musculus | mus musculus | bos taurus | Park, E., MacKinnon, R. | 3.76 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV6 | Kappa | null | null | null | null | null |
7cw3 | o | p | 0 | N | M | protein | protein | NA | NA | fab light chain | fab heavy chain | VIRUS/IMMUNE SYSTEM | 08/27/20 | Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex) | CHIKUNGUNYA VIRUS; MUS MUSCULUS | mus musculus | mus musculus | chikungunya virus | chikungunya virus | Zhou, Q.F., Fox, J.M., Earnest, J.T., Ng, T.S., Kim, A.S., Fibriansah, G., Kostyuchenko, V.A., Shu, B., Diamond, M.S., Lok, S.M. | 9.4 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
6vmk | l | k | 0 | m | protein | null | unknown | HYDROLASE/IMMUNE SYSTEM | 01/28/20 | Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wu, P., Harris, S.F., Eigenbrot, C. | 3.01 | X-RAY DIFFRACTION | 0.215 | 0.174 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5gis | H | L | 0 | C | peptide | null | thr-lys-pro-ile-thr-ile-gly-ser-his-ala-his-gly-asp-gln-tyr-lys | IMMUNE SYSTEM | 06/24/16 | Crystal structure of a Fab fragment with its ligand peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Kitago, Y., Kaneko, K.K., Ogasawara, S., Kato, Y., Takagi, J. | 1.93 | X-RAY DIFFRACTION | 0.216 | 0.186 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
6zpl | F | null | 0 | A | protein | null | sodium- and chloride-dependent glycine transporter 1 | MEMBRANE PROTEIN | 07/08/20 | Inward-open structure of human glycine transporter 1 in complex with a benzoylisoindoline inhibitor, sybody Sb_GlyT1#7 and bound Na and Cl ions. | HOMO SAPIENS; HUNGATEICLOSTRIDIUM THERMOCELLUM (STRAIN ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372); UNIDENTIFIED | unidentified | null | homo sapiens | Shahsavar, A., Stohler, P., Bourenkov, G., Zimmermann, I., Siegrist, M., Guba, W., Pinard, E., Sinning, S., Seeger, M.A., Schneider, T.R., Dawson, R.J.P., Nissen, P. | 3.945 | X-RAY DIFFRACTION | 0.291 | 0.277 | false | true | IGHV1 | null | null | null | null | null | null | null |
7ew4 | S | s | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 05/24/21 | Cryo-EM structure of CYM-5541-bound Sphingosine 1-phosphate receptor 3 in complex with Gi protein | HOMO SAPIENS | homo sapiens | null | homo sapiens | homo sapiens | Zhao, C., Wang, W., Wang, H.L., Shao, Z.H. | 3.2 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6p9h | H | L | 0 | A | protein | null | iron-regulated heme-iron binding protein | IMMUNE SYSTEM | 06/17/20 | Crystal structure of human anti staphylococcus aureus antibody STAU-281 Fab in complex with IsdB NEAT2 domain | STAPHYLOCOCCUS AUREUS; HOMO SAPIENS | homo sapiens | homo sapiens | staphylococcus aureus | Dong, J., Crowe, J.E. | 3.003 | X-RAY DIFFRACTION | 0.225 | 0.206 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1ngw | H | L | 0 | H | Hapten | MMP | N-METHYLMESOPORPHYRIN | IMMUNE SYSTEM | 12/18/02 | Chimeric Affinity Matured Fab 7g12 complexed with mesoporphyrin | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | mus musculus, homo sapiens | Yin, J., Andryski, S.E., Beuscher IV, A.E., Stevens, R.C., Schultz, P.G. | 2.6 | X-RAY DIFFRACTION | 0.318 | 0.275 | false | true | IGHV1 | IGKV6 | Kappa | 0 | -10.48 | SPR | null | 12552112 |
1b0w | null | C | 0 | null | null | null | null | IMMUNE SYSTEM | 11/13/98 | Structural comparison of amyloidogenic light chain dimer in two crystal forms with nonamyloidogenic counterparts | HOMO SAPIENS | null | homo sapiens | null | Schormann, N., Benson, M.D. | 1.8 | X-RAY DIFFRACTION | 0.299 | 0.226 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
3wfh | A | B | 0 | B | Hapten | P2E | (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid | IMMUNE SYSTEM | 07/19/13 | Crystal structure of anti-Prostaglandin E2 Fab fragment PGE2 complex | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Sugahara, M., Ago, H., Saino, H., Miyano, M. | 1.9 | X-RAY DIFFRACTION | 0.200 | 0.168 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3u9u | A | B | 0 | F | protein | null | receptor tyrosine-protein kinase erbb-4 | Transferase | 10/19/11 | Crystal Structure of Extracellular Domain of Human ErbB4/Her4 in complex with the Fab fragment of mAb1479 | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Hollmen, M., Liu, P., Wildiers, H., Reinvall, I., Vandorpe, T., Smeets, A., Deraedt, K., Vahlberg, T., Joensuu, H., Leahy, D.J., Schoffski, P., Elenius, K. | 3.42 | X-RAY DIFFRACTION | 0.272 | 0.234 | false | true | IGHV8 | IGKV1 | Kappa | null | null | null | null | null |
5ty6 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/18/16 | Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 13-1b02 Fab. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Joyce, M.G., Andrews, S.F., Mascola, J.R., McDermott, A.B., Kwong, P.D. | 1.361 | X-RAY DIFFRACTION | 0.173 | 0.159 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5az2 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/16/15 | Crystal structure of the Fab fragment of 9E5, a murine monoclonal antibody specific for human epiregulin | MUS MUSCULUS | mus musculus | mus musculus | null | Kado, Y., Mizohata, E., Nagatoishi, S., Iijima, M., Shinoda, K., Miyafusa, T., Nakayama, T., Yoshizumi, T., Sugiyama, A., Kawamura, T., Lee, Y.H., Matsumura, H., Doi, H., Fujitani, H., Kodama, T., Shibasaki, Y., Tsumoto, K., Inoue, T. | 1.603 | X-RAY DIFFRACTION | 0.238 | 0.193 | false | false | IGHV14 | IGKV19 | Kappa | null | null | null | null | null |
4u0r | B | C | 0 | A | protein | null | reticulocyte binding protein 5 | IMMUNE SYSTEM | 07/14/14 | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody 9AD4 | PLASMODIUM FALCIPARUM; ORYCTOLAGUS CUNICULUS | oryctolagus cuniculus | oryctolagus cuniculus | plasmodium falciparum | Wright, K.E., Hjerrild, K.A., Bartlett, J., Douglas, A.D., Jin, J., Brown, R.E., Ashfield, R., Clemmensen, S.B., de Jongh, W.A., Draper, S.J., Higgins, M.K. | 2.3 | X-RAY DIFFRACTION | 0.258 | 0.221 | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
2adf | H | L | 0 | A | protein | null | von willebrand factor | BLOOD CLOTTING/IMMUNE SYSTEM | 07/20/05 | Crystal Structure and Paratope Determination of 82D6A3, an Antithrombotic Antibody Directed Against the von Willebrand factor A3-Domain | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Staelens, S., Hadders, M.A., Vauterin, S., Platteau, C., Vanhoorelbeke, K., Huizinga, E.G., Deckmyn, H. | 1.9 | X-RAY DIFFRACTION | 0.220 | 0.191 | false | false | IGHV9 | IGKV19 | Kappa | null | null | null | null | null |
6db8 | H | L | 0 | R | nucleic-acid | null | rna (60-mer) | RNA/IMMUNE SYSTEM | 05/02/18 | Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer | SYNTHETIC CONSTRUCT; SYNTHETIC CONSTRUCT | synthetic construct | synthetic construct | synthetic construct | Shao, Y., Shelke, S.A., Laski, A., Piccirilli, J.A. | 1.86541 | X-RAY DIFFRACTION | 0.233 | 0.219 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7rlx | A | B | 0 | P | peptide | null | peptide from circumsporozoite protein variant vk210 | ANTIMICROBIAL PROTEIN | 07/26/21 | Antibody 2F2 in complex with P. vivax CSP peptide GDRADGQPAGDRAAGQPA | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium vivax | Kucharska, I., Julien, J.P. | 1.97 | X-RAY DIFFRACTION | 0.235 | 0.186 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1bfv | H | L | 0 | H | Hapten | STG | ESTRIOL 3-(B-D-GLUCURONIDE) | IMMUNOGLOBULIN | 05/27/97 | MONOCLONAL ANTIBODY FRAGMENT FV4155 FROM E. COLI | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Trinh, C.H., Phillips, S.E.V. | 2.1 | X-RAY DIFFRACTION | 0.271 | 0.187 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
6gwp | C | null | 0 | A | protein | null | plasminogen activator inhibitor-1 | HYDROLASE | 06/25/18 | Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64) | HOMO SAPIENS; VICUGNA PACOS | vicugna pacos | null | homo sapiens | Sillen, M., Weeks, S.D., Strelkov, S.V., Declerck, P.J. | 2.28 | X-RAY DIFFRACTION | 0.225 | 0.203 | false | true | IGHV1 | null | null | null | null | null | null | null |
5iwl | A | a | 0 | D | protein | null | leukocyte surface antigen cd47 | CELL ADHESION | 03/22/16 | CD47-diabody complex | HOMO SAPIENS | homo sapiens | null | homo sapiens | Di, W., Jude, K.M., Garcia, K.C. | 2.8 | X-RAY DIFFRACTION | 0.267 | 0.221 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6pec | H | L | 0 | A | peptide | null | hiv-1 fusion peptide residue 512-519 | IMMUNE SYSTEM | 06/20/19 | Vaccine-elicited NHP FP-targeting antibody DF2F-e.01 in complex with HIV fusion peptide (residue 512-519) | MACACA MULATTA; SYNTHETIC CONSTRUCT | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Xu, K., Liu, K., Wang, Y., Kwong, P.D. | 1.746 | X-RAY DIFFRACTION | 0.215 | 0.194 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6u51 | C | null | 0 | B | protein | null | nucleoprotein | IMMUNE SYSTEM | 08/26/19 | Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) Complexed with Sudan ebolavirus Nucleoprotein C-terminal Domain 610-738 | LAMA GLAMA; SUDAN EBOLAVIRUS (STRAIN BONIFACE-76) | lama glama | null | sudan ebolavirus (strain boniface-76) | Taylor, A.B., Sherwood, L.J., Hart, P.J., Hayhurst, A. | 2.52 | X-RAY DIFFRACTION | 0.250 | 0.208 | false | true | unknown | unknown | unknown | null | null | null | null | null |
6apd | J | L | 0 | C | protein | null | fusion glycoprotein f0,envelope glycoprotein | IMMUNE SYSTEM | 08/17/17 | Crystal structure of RSV F bound by AM22 and the infant antibody ADI-19425 | RESPIRATORY SYNCYTIAL VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | respiratory syncytial virus, humanimmunodeficiency virus 1 | Wrapp, D., McLellan, J.S. | 4.1 | X-RAY DIFFRACTION | 0.256 | 0.204 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
6lfo | S | s | 0 | A | C | B | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 12/03/19 | Cryo-EM structure of a class A GPCR monomer | HOMO SAPIENS | homo sapiens | null | homo sapiens | homo sapiens | homo sapiens | Liu, Z.J., Hua, T., Liu, K.W., Wu, L.J. | 3.4 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7q6c | K | null | 0 | null | null | null | null | IMMUNE SYSTEM | 11/06/21 | complement C6 FIM1-2 bound to CP010 antibody | HOMO SAPIENS; MUS MUSCULUS; LAMA GLAMA | lama glama | null | null | Olesen, H.G., Andersen, G.R. | 2.29274 | X-RAY DIFFRACTION | 0.233 | 0.208 | false | true | IGHV1 | null | null | null | null | null | null | null |
2ny1 | D | C | 0 | A | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/20/06 | HIV-1 gp120 Envelope Glycoprotein (I109C, T257S, S334A, S375W, Q428C) Complexed with CD4 and Antibody 17b | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X, Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D. | 1.99 | X-RAY DIFFRACTION | 0.250 | 0.209 | false | true | IGHV1 | IGKV3 | Kappa | 0 | null | SPR | null | 17301785 |
1maj | null | A | 9 | null | null | null | null | IMMUNOGLOBULIN | 09/16/93 | SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN | MUS MUSCULUS | null | mus musculus | null | Constantine, K.L., Friedrichs, M.S., Metzler, W.J., Wittekind, M., Hensley, P., Mueller, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
5i17 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/05/16 | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV3-20 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G. | 3.3 | X-RAY DIFFRACTION | 0.247 | 0.202 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5ujz | H | h | 0 | C | protein | null | hemagglutinin ha1 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/19/17 | CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 1 | HOMO SAPIENS; INFLUENZA A VIRUS; INFLUENZA A VIRUS (A/SOLOMON ISLANDS/3/2006(H1N1)) | homo sapiens | null | influenza a virus (a/solomonislands/3/2006(h1n1)) | Liu, Y., Pan, J., Caradonna, T., Jenni, S., Raymond, D.D., Schmidt, A.G., Harrison, S.C., Grigorieff, N. | 4.8 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
3ri5 | I | O | 0 | D | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | transport protein/immune system | 04/12/11 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and picrotoxin | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Hibbs, R.E., Gouaux, E. | 3.4 | X-RAY DIFFRACTION | 0.248 | 0.232 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5imm | B | null | 0 | A | protein | null | protein vsig4 | IMMUNE SYSTEM | 03/06/16 | Nanobody targeting mouse Vsig4 in Spacegroup P212121 | MUS MUSCULUS; CAMELIDAE | camelidae | null | mus musculus | Wen, Y., Zheng, F. | 1.2 | X-RAY DIFFRACTION | 0.176 | 0.156 | false | true | IGHV1 | null | null | 0 | -11.535955 | ITC | null | TBD |
1kno | D | C | 0 | D | Hapten | PNP | METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER | CATALYTIC ANTIBODY | 09/11/95 | CRYSTAL STRUCTURE OF THE COMPLEX OF A CATALYTIC ANTIBODY FAB WITH A TRANSITION STATE ANALOG: STRUCTURAL SIMILARITIES IN ESTERASE-LIKE ABZYMES | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Charbonnier, J.-B., Gigant, B., Knossow, M. | 3.2 | X-RAY DIFFRACTION | 0.272 | 0.200 | false | false | IGHV5 | IGKV9 | Kappa | null | null | null | null | null |
3t0x | null | A | 0 | A | Hapten | DIW | 1-(3-SULFOPROPYL)-4-[(1E,3E)-3-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)PROP-1-EN-1-YL]QUINOLINIUM | DYE-BINDING PROTEIN | 07/20/11 | Fluorogen Activating Protein M8VLA4(S55P) in complex with dimethylindole red | HOMO SAPIENS | null | homo sapiens | homo sapiens | Stanfield, R., Senutovitch, N., Bhattacharyya, S., Rule, G., Wilson, I.A., Armitage, B., Waggoner, A.S., Berget, P. | 1.96 | X-RAY DIFFRACTION | 0.242 | 0.209 | false | true | null | IGLV1 | Lambda | 0 | -10.913953 | Unknown | null | TBD |
5mp1 | F | G | 0 | E | peptide | null | microtubule-associated protein tau | IMMUNE SYSTEM | 12/15/16 | Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 7.5 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Skrabana, R., Novak, M., Cehlar, O., Kontsekova, E. | 3.1 | X-RAY DIFFRACTION | 0.268 | 0.222 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
6qkd | I | null | 0 | null | null | null | null | IMMUNE SYSTEM | 01/29/19 | CRYSTAL STRUCTURE OF vhh-based FAB-fragment of antibody BCD-085 | LAMA GLAMA | lama glama | null | null | Kostareva, O.S., Kolyadenko, I.A., Ulitin, A.B., Ekimova, V.M., Evdokimov, S.R., Garber, M.B., Tishchenko, T.V., Gabdulkhakov, A.G. | 1.9 | X-RAY DIFFRACTION | 0.228 | 0.169 | false | true | IGHV1 | null | null | null | null | null | null | null |
4wht | A | B | 0 | a | peptide | null | unknown | VIRAL PROTEIN | 09/23/14 | Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P1 crystal form | HEPATITIS C VIRUS; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | hepatitis c virus | Krey, T., Rey, F.A. | 2.22 | X-RAY DIFFRACTION | 0.243 | 0.209 | false | true | IGHV5 | IGKV2 | Kappa | 0 | -11.053614 | Unknown | null | TBD |
2kh2 | B | b | 20 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
4i0c | D | null | 0 | A | protein | null | lysozyme c | IMMUNE SYSTEM/HYDROLASE | 11/16/12 | The structure of the camelid antibody cAbHuL5 in complex with human lysozyme | HOMO SAPIENS; CAMELUS DROMEDARIUS | camelus dromedarius | null | homo sapiens | De Genst, E., Chan, P.H., Pardon, E., Kumita, J.R., Christodoulou, J., Menzer, L., Chirgadze, D.Y., Robinson, C.V., Muyldermans, S., Matagne, A., Wyns, L., Dobson, C.M., Dumoulin, M. | 1.95 | X-RAY DIFFRACTION | 0.219 | 0.187 | false | true | IGHV1 | null | null | null | null | null | null | null |
5xli | d | b | 0 | null | null | null | null | IMMUNE SYSTEM | 05/10/17 | Structure of anti-Angiotensin II type2 receptor antibody (D5711-4A03) | MUS MUSCULUS | mus musculus | mus musculus | null | Asada, H., Horita, S., Iwata, S., Hirata, K. | 1.696 | X-RAY DIFFRACTION | 0.216 | 0.180 | false | false | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7ora | H | L | 0 | C | protein | null | spike protein s1 | VIRAL PROTEIN | 06/04/21 | Crystal structure of the T478K mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-45 and COVOX-253 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 2.6 | X-RAY DIFFRACTION | 0.245 | 0.204 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7uaq | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 03/13/22 | Structure of the SARS-CoV-2 NTD in complex with C1520, local refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Barnes, C.O. | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV4 | Lambda | null | null | null | null | null |
4k07 | null | D | 0 | null | null | null | null | IMMUNE SYSTEM | 04/03/13 | Crystal structure of the amyloid-forming immunoglobulin AL-103 cis-proline 95 mutant | HOMO SAPIENS | null | homo sapiens | null | Thompson, J.R., Berkholz, D.S., Mahlum, E.W., Ramirez-Alvarado, M. | 2.83 | X-RAY DIFFRACTION | 0.236 | 0.202 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
7tb8 | D | E | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 12/21/21 | Cryo-EM structure of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, T., Tsybovsky, T., Kwong, P.D. | 2.83 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6mph | Q | R | 0 | C | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN | 10/06/18 | Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Kwong, P.D. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
1u8n | B | A | 0 | C | peptide | null | gp41 peptide | IMMUNE SYSTEM | 08/06/04 | Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELDKFAS | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Bryson, S., Julien, J.-P., Hynes, R.C., Pai, E.F. | 2.56 | X-RAY DIFFRACTION | 0.230 | 0.205 | false | false | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
4yk4 | C | B | 0 | A | protein | null | hemagglutinin | Viral protein/Immune system | 03/03/15 | Human antibody 641 I-9 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006 | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Schmidt, A.G., Harrison, S.C. | 2.8 | X-RAY DIFFRACTION | 0.260 | 0.220 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -8.784229 | BLI | null | TBD |
5yy5 | H | L | 0 | A | protein | null | mers-cov rbd | VIRAL PROTEIN | 12/08/17 | Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein | MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | middle east respiratory syndrome coronavirus | Zhang, S.Y., Wang, P.F., Zhou, P.P., Wang, X.Q., Zhang, L.Q. | 2.8 | X-RAY DIFFRACTION | 0.279 | 0.246 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7n9e | D | null | 0 | A | B | protein | protein | NA | NA | spike glycoprotein | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/17/21 | Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB34 | LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | lama glama | null | severe acute respiratory syndrome coronavirus2 | severe acute respiratory syndrome coronavirus2 | Sun, D., Zhang, C., Shi, Y. | 3.52 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7ws0 | E | D | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 01/28/22 | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Guo, H., Gao, Y., Ji, X., Yang, H. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6i8s | G | K | 0 | C | protein | null | plasminogen activator inhibitor 1 | BLOOD CLOTTING | 11/21/18 | Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1 | HOMO SAPIENS; ESCHERICHIA COLI | null | null | homo sapiens | Vousden, K.A., Lundqvist, T., Popovic, B. | 2.9 | X-RAY DIFFRACTION | 0.243 | 0.219 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1maj | null | A | 2 | null | null | null | null | IMMUNOGLOBULIN | 09/16/93 | SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN | MUS MUSCULUS | null | mus musculus | null | Constantine, K.L., Friedrichs, M.S., Metzler, W.J., Wittekind, M., Hensley, P., Mueller, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
5vl2 | E | null | 0 | E | Hapten | 9EG | N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea | UNKNOWN FUNCTION | 04/24/17 | The hapten triclocarban bound to the single domain camelid nanobody VHH T4 | LAMA GLAMA | lama glama | null | lama glama | Tabares-da Rosa, S., Gonzalez-Sapienza, G., Wilson, D.K. | 1.9 | X-RAY DIFFRACTION | 0.263 | 0.219 | false | true | IGHV1 | null | null | null | null | null | null | null |
4i2x | D | C | 0 | F | protein | null | signal-regulatory protein gamma | IMMUNE SYSTEM | 11/23/12 | Crystal structure of Signal Regulatory Protein gamma (SIRP-gamma) in complex with FabOX117 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Nettleship, J.E., Ren, J., Stuart, D.I., Owens, R.J., Oxford Protein Production Facility (OPPF) | 2.48 | X-RAY DIFFRACTION | 0.260 | 0.196 | false | false | IGHV1 | IGKV6 | Kappa | 0.000001 | -8.077442 | AUC | null | TBD |
4z9k | B | null | 0 | A | protein | null | ricin | Hydrolase/Immune system | 04/10/15 | Ricin A chain bound to camelid nanobody (VHH2)(F5) | RICINUS COMMUNIS; VICUGNA PACOS | vicugna pacos | null | ricinus communis | Rudolph, M.J. | 1.5 | X-RAY DIFFRACTION | 0.195 | 0.178 | false | true | IGHV1 | null | null | 0 | -11.811049 | SPR | null | TBD |
4s1s | H | L | 0 | G | protein | null | clade a/e 93th057 hiv-1 gp120 core | VIRAL PROTEIN/IMMUNE SYSTEM/INHIBITOR | 01/14/15 | Crystal structure of a VRC01-lineage antibody, 45-VRC01.H5.F-185917, in complex with clade A/E HIV-1 gp120 core | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kwon, Y.D., Yang, Y., Zhang, B., Kwong, P.D. | 3.39 | X-RAY DIFFRACTION | 0.300 | 0.262 | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
7v0v | A | null | 8 | null | null | null | null | IMMUNE SYSTEM | 05/11/22 | GFP Nanobody NMR Structure | SYNTHETIC CONSTRUCT | synthetic construct | null | null | Mueller, G.A. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6e8v | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 09/04/19 | The crystal structure of bovine ultralong antibody BOV-1 | BOS TAURUS | bos taurus | bos taurus | null | Dong, J., Crowe, J.E. | 3.79 | X-RAY DIFFRACTION | 0.275 | 0.218 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
4kk5 | E | F | 0 | B | protein | null | h(+)/cl(-) exchange transporter clca | TRANSPORT PROTEIN | 05/05/13 | Structure of the CLC-ec1 deltaNC construct in 20mM fluoride and 20mM bromide | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Lim, H.-H., Miller, C. | 3.171 | X-RAY DIFFRACTION | 0.271 | 0.232 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
7lbe | H | G | 0 | A | protein | null | envelope glycoprotein h | VIRAL PROTEIN/Immune System | 01/07/21 | CryoEM structure of the HCMV Trimer gHgLgO in complex with neutralizing fabs 13H11 and MSL-109 | HUMAN CYTOMEGALOVIRUS (STRAIN MERLIN); HUMAN CYTOMEGALOVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | human cytomegalovirus (strain merlin) | Kschonsak, M., Rouge, L., Arthur, C.P., Hoangdung, H., Patel, N., Kim, I., Johnson, M., Kraft, E., Rohou, A.L., Gill, A., Martinez-Martin, N., Payandeh, J., Ciferri, C. | 2.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
7qne | G | null | 0 | A | E | protein | protein | NA | NA | gaba(a) receptor subunit alpha-1 | gamma-aminobutyric acid receptor subunit beta-3 | MEMBRANE PROTEIN | 12/20/21 | Cryo-EM structure of human full-length synaptic alpha1beta3gamma2 GABA(A)R in complex with Ro15-4513 and megabody Mb38 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | homo sapiens | Sente, A., Desai, R., Naydenova, K., Malinauskas, T., Jounaidi, Y., Miehling, J., Zhou, X., Masiulis, S., Hardwick, S.W., Chirgadze, D.Y., Miller, K.W., Aricescu, A.R. | 2.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4uil | H | L | 0 | H | Hapten | QI9 | Quinine | null | 03/30/15 | crystal structure of quinine-dependent Fab 314.1 with quinine | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Zhu, J., Zhu, J., Bougie, D.W., Aster, R.H., Springer, T.A. | 2.853 | X-RAY DIFFRACTION | 0.3352 | 0.2685 | false | false | IGHV1 | IGKV10 | Kappa | 0 | -9.872451 | Unknown | null | TBD |
7ks9 | H | L | 0 | B | protein | null | spike glycoprotein | Viral Protein/IMMUNE SYSTEM | 11/21/20 | Cryo-EM structure of prefusion SARS-CoV-2 spike glycoprotein in complex with 910-30 Fab | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Cerutti, G., Shapiro, L. | 4.75 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4xce | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 12/17/14 | Crystal structure of human 4E10 Fab crystalized in the presence of Phosphatidylcholine (06:0 PC); C2 space group | HOMO SAPIENS | homo sapiens | homo sapiens | null | Irimia, A., Stanfield, R.L., Wilson, I.A. | 2.93 | X-RAY DIFFRACTION | 0.247 | 0.192 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
2ap2 | D | C | 0 | Q | peptide | null | protein (p-glycoprotein) | IMMUNE SYSTEM | 03/22/99 | SINGLE CHAIN FV OF C219 IN COMPLEX WITH SYNTHETIC EPITOPE PEPTIDE | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Van Den Elsen, J.M.H., Rose, D.R. | 2.4 | X-RAY DIFFRACTION | 0.274 | 0.221 | true | true | IGHV14 | IGKV8 | Kappa | null | null | null | null | null |
7a4d | I | null | 0 | L | peptide | null | aph coiled-coil | DE NOVO PROTEIN | 08/19/20 | Crystal structure of the APH coiled-coil in complex with nanobodies Nb28 and Nb30 | LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | synthetic construct | Hadzi, S. | 2.694 | X-RAY DIFFRACTION | 0.223 | 0.177 | false | true | IGHV1 | null | null | null | null | null | null | null |
4r9y | N | M | 0 | A | C | protein | protein | NA | NA | platelet factor 4 | platelet factor 4 | IMMUNE SYSTEM/Cytokine | 09/08/14 | Crystal structure of KKOFab in complex with platelet factor 4 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | homo sapiens | Cai, Z., Zhu, Z., Liu, Q., Greene, M.I. | 4.11 | X-RAY DIFFRACTION | 0.382 | 0.317 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
5i1d | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 02/05/16 | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV4-1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G. | 2.0 | X-RAY DIFFRACTION | 0.251 | 0.216 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
4fz8 | H | L | 0 | H | carbohydrate | NAG | N-ACETYL-D-GLUCOSAMINE | IMMUNE SYSTEM | 07/06/12 | Crystal structure of C11 Fab, an ADCC mediating anti-HIV-1 antibody. | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wu, X., Tolbert, W.D., Pazgier, M. | 2.66 | X-RAY DIFFRACTION | 0.313 | 0.253 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
6xsw | A | B | 0 | C | protein | null | neurogenic locus notch homolog protein 3 | SIGNALING PROTEIN/Immune System | 07/16/20 | Structure of the Notch3 NRR in complex with an antibody Fab Fragment | RATTUS NORVEGICUS; HOMO SAPIENS | rattus norvegicus | rattus norvegicus | homo sapiens | Bard, J. | 2.98 | X-RAY DIFFRACTION | 0.256 | 0.233 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4kml | B | null | 0 | A | protein | null | major prion protein | MEMBRANE PROTEIN/PROTEIN BINDING | 05/08/13 | Probing the N-terminal beta-sheet conversion in the crystal structure of the full-length human prion protein bound to a Nanobody | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Abskharon, R.N.N, Giachin, G., Wohlkonig, A., Soror, S.H., Pardon, E., Legname, G., Steyaert, J. | 1.5 | X-RAY DIFFRACTION | 0.192 | 0.175 | false | true | IGHV3 | null | null | null | null | null | null | null |
7m6h | E | G | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/ANTIVIRAL PROTEIN | 03/25/21 | Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG7-20 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Barnes, C.O., Bjorkman, P.J. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7a29 | E | null | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 08/16/20 | Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 2-up conformation | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SYNTHETIC CONSTRUCT | synthetic construct | null | severe acute respiratory syndrome coronavirus2 | Hallberg, B.M., Das, H. | 2.94 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6z3k | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/20/20 | Structure of protective antibody 38-1-10A Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Zhou, D., Fry, E.E., Ren, J., Stuart, D.I. | 2.7 | X-RAY DIFFRACTION | 0.234 | 0.188 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
5esv | H | L | 0 | G | protein | null | 2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthase,envelope glycoprotein gp160 | IMMUNE SYSTEM | 11/17/15 | Crystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade C Superinfecting Strain of Donor CAP256. | HOMO SAPIENS; HAEMOPHILUS INFLUENZAE | homo sapiens | homo sapiens | haemophilus influenzae, human immunodeficiencyvirus 1, haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd) | Gorman, J., Yang, M., Kwong, P.D. | 3.105 | X-RAY DIFFRACTION | 0.259 | 0.209 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
3l5w | B | A | 0 | J | protein | null | interleukin-13 | IMMUNE SYSTEM | 12/22/09 | Crystal structure of the complex between IL-13 and C836 FAB | MUS MUSCULUS, HOMO SAPIENS; HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | homo sapiens | Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L. | 2.0 | X-RAY DIFFRACTION | 0.253 | 0.205 | false | true | IGHV8 | IGKV16 | Kappa | 0 | -14 | SPR | 25 | 20226193 |
2hg5 | A | B | 0 | C | protein | null | kcsa channel | MEMBRANE PROTEIN | 06/26/06 | Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Valiyaveetil, F.I., MacKinnon, R., Muir, T.W. | 2.75 | X-RAY DIFFRACTION | 0.271 | 0.239 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
3dv4 | B | A | 0 | B | carbohydrate | KDO | 3-DEOXY-D-MANNO-OCT-2-ULOSONIC ACID | IMMUNE SYSTEM | 07/18/08 | Crystal structure of SAG506-01, tetragonal, crystal 1 | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Brooks, C.L., Blackler, R.J., Gerstenbruch, S., Kosma, P., Muller-Loennies, S., Brade, H., Evans, S.V. | 1.95 | X-RAY DIFFRACTION | 0.336 | 0.269 | false | true | IGHV7 | IGKV8 | Kappa | null | null | null | null | null |
6pds | B | A | 0 | C | peptide | null | hiv-1 fusion peptide residue 512-519 | IMMUNE SYSTEM | 06/19/19 | Vaccine-elicited NHP FP-targeting antibody 0PV-a.04 in complex with HIV fusion peptide (residue 512-519) | MACACA MULATTA; SYNTHETIC CONSTRUCT | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Xu, K., Liu, K., Wang, Y., Kwong, P.D. | 1.893 | X-RAY DIFFRACTION | 0.220 | 0.193 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6qtl | F | null | 0 | E | Hapten | CFF | CAFFEINE | BIOSYNTHETIC PROTEIN | 04/10/19 | Caffeine recognizing nanobody | CAMELIDAE | camelidae | null | camelidae | Lesne, J., Guichou, J.F., Labesse, G., Cohen-Gonsaud, M. | 2.25 | X-RAY DIFFRACTION | 0.259 | 0.194 | false | true | IGHV1 | null | null | null | null | null | null | null |
5ywy | H | L | 0 | A | protein | null | prostaglandin e2 receptor ep4 subtype,prostaglandin e2receptor ep4 subtype | SIGNALING PROTEIN-IMMUNE SYSTEM | 11/30/17 | Crystal structure of the clinically important GPCR in complex with functional antibody. | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Toyoda, Y., Morimoto, K., Suno, R., Horita, S., Iwata, S., Kobayashi, T. | 3.2 | X-RAY DIFFRACTION | 0.252 | 0.222 | false | true | IGHV1 | IGKV14 | Kappa | 0 | -9.862322 | Unknown | null | TBD |
5w08 | I | J | 0 | B | protein | null | hemagglutinin ha1 | VIRAL PROTEIN/IMMUNE SYSTEM | 05/30/17 | A/Texas/50/2012(H3N2) Influenza hemagglutinin in complex with K03.12 Fab | INFLUENZA A VIRUS (A/TEXAS/50/2012(H3N2)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/texas/50/2012(h3n2)) | McCarthy, K.R., Harrison, S.C. | 2.6 | X-RAY DIFFRACTION | 0.262 | 0.240 | false | true | IGHV1 | IGLV2 | Lambda | 0 | -10.092596 | SPR | null | TBD |
5viy | O | P | 0 | C | E | protein | protein | NA | NA | envelope glycoprotein gp160 | envelope glycoprotein gp160 | VIRAL PROTEIN/IMMUNE SYSTEM | 04/17/17 | BG505 SOSIP.664 in complex with broadly neutralizing antibodies BG1 and 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Wang, H., Bjorkman, P.J. | 6.2 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
7mlv | L | M | 0 | A | protein | null | glycine receptor alpha 1 | MEMBRANE PROTEIN, SIGNALING PROTEIN | 04/29/21 | Cryo-EM reveals partially and fully assembled native glycine receptors,homomeric tetramer | RATTUS NORVEGICUS; SUS SCROFA | rattus norvegicus | rattus norvegicus | sus scrofa | Zhu, H., Gouaux, E. | 4.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
6e9q | E | F | 0 | null | null | null | null | IMMUNE SYSTEM | 05/01/19 | The crystal structure of bovine ultralong antibody BOV-6 | BOS TAURUS | bos taurus | bos taurus | null | Dong, J., Crowe, J.E. | 3.4 | X-RAY DIFFRACTION | 0.311 | 0.254 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5vz1 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 05/26/17 | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) | HOMO SAPIENS | homo sapiens | homo sapiens | null | Radwanska, M.J., Derewenda, U., Kossiakoff, A., Derewenda, Z.S. | 2.112 | X-RAY DIFFRACTION | 0.268 | 0.218 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6cr1 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/16/18 | adalimumab EFab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Arndt, J.W. | 1.521 | X-RAY DIFFRACTION | 0.179 | 0.153 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4lou | C | D | 0 | A | protein | null | h(+)/cl(-) exchange transporter clca | membrane protein, tranport protein | 07/13/13 | Structure of the E148Q mutant of CLC-ec1 deltaNC construct in the absence of halide | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Lim, H.-H., Miller, C. | 2.981 | X-RAY DIFFRACTION | 0.253 | 0.210 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
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