pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5ukb | b | null | 0 | B | protein | null | nucleocapsid | Viral Protein/RNA/Immune System | 01/20/17 | VSV N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1004 | ESCHERICHIA COLI; VESICULAR STOMATITIS INDIANA VIRUS; VICUGNA PACOS | vicugna pacos | null | vesicular stomatitis indiana virus | Hanke, L., Knockenhauer, K.E., Ploegh, H.L., Schwartz, T.U. | 5.473 | X-RAY DIFFRACTION | 0.338 | 0.336 | false | false | IGHV1 | null | null | null | null | null | null | null |
7s4g | H | L | 0 | J | peptide | null | lymphocyte antigen 6 complex locus protein g6d | SIGNALING PROTEIN | 09/08/21 | Fab fragment bound to the Cter peptide of Ly6G6D | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Rouge, L., Lupardus, P. | 2.2 | X-RAY DIFFRACTION | 0.235 | 0.192 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6o41 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/27/19 | Crystal structure of the unbound PGZL1 germline Fab fragment (PGZL1_gVmDmJ) | HOMO SAPIENS; STREPTOCOCCUS SP. GROUP G | homo sapiens | homo sapiens | null | Irimia, A., Wilson, I.A. | 2.465 | X-RAY DIFFRACTION | 0.219 | 0.169 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3v6o | D | F | 0 | B | protein | null | leptin receptor | IMMUNE SYSTEM | 12/20/11 | Leptin Receptor-antibody complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Carpenter, B., Hemsworth, G.R., Ross, R.J., Artymiuk, P.J. | 1.95 | X-RAY DIFFRACTION | 0.213 | 0.171 | false | false | IGHV2 | IGKV6 | Kappa | null | null | null | null | null |
3eff | B | A | 0 | M | N | protein | protein | NA | NA | voltage-gated potassium channel | voltage-gated potassium channel | MEMBRANE PROTEIN | 09/08/08 | The Crystal Structure of Full-Length KcsA in its Closed Conformation | MUS MUSCULUS; STREPTOMYCES LIVIDANS | mus musculus | mus musculus | streptomyces lividans | streptomyces lividans | Uysal, S., Vasquez, V., Tereshko, T., Esaki, K., Fellouse,F.A., Sidhu, S.S., Koide, S., Perozo, E., Kossiakoff, A. | 3.8 | X-RAY DIFFRACTION | 0.331 | 0.270 | false | false | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4jpv | H | L | 0 | G | protein | null | hiv-1 clade a strain 93th057 gp120 with loop d and loopd v5replaced from hiv strain 3415v1 | viral protein/immune system | 03/19/13 | Crystal structure of broadly and potently neutralizing antibody 3bnc117 in complex with hiv-1 gp120 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Moquin, S., Kwong, P.D. | 2.827 | X-RAY DIFFRACTION | 0.259 | 0.199 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5f9w | B | C | 0 | A | protein | null | clade a/e 93th057 hiv-1 gp120 core | IMMUNE SYSTEM | 12/10/15 | Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235 in complex with HIV-1 clade A/E 93TH057 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Chen, L., Zhou, T., Kwong, P.D. | 2.8911 | X-RAY DIFFRACTION | 0.232 | 0.180 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5cws | B | A | 0 | E | C | D | F | protein | protein | protein | peptide | NA | NA | NA | NA | nucleoporin nup57 | nucleoporin nsp1 | nucleoporin nup49 | nucleoporin nic96 | PROTEIN TRANSPORT | 07/28/15 | Crystal structure of the intact Chaetomium thermophilum Nsp1-Nup49-Nup57 channel nucleoporin heterotrimer bound to its Nic96 nuclear pore complex attachment site | HOMO SAPIENS; CHAETOMIUM THERMOPHILUM (STRAIN DSM 1495 / CBS 144.50 / IMI 039719); CHAETOMIUM THERMOPHILUM | homo sapiens | homo sapiens | chaetomium thermophilum (strain dsm 1495 / cbs144.50 / imi 039719) | chaetomium thermophilum (strain dsm 1495 / cbs144.50 / imi 039719) | chaetomium thermophilum | chaetomium thermophilum (strain dsm 1495 / cbs144.50 / imi 039719) | Bley, C.J., Petrovic, S., Paduch, M., Lu, V., Kossiakoff, A.A., Hoelz, A. | 3.77 | X-RAY DIFFRACTION | 0.265 | 0.229 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7ley | H | I | 0 | C | protein | null | arginase-1 | HYDROLASE/IMMUNE SYSTEM | 01/15/21 | Trimeric human Arginase 1 in complex with mAb5 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gomez-Llorente, Y., Scapin, G., Palte, R.L. | 3.05 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6dcv | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/08/18 | Crystal structure of human anti-tau antibody CBTAU-27.1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Zhu, X., Zhang, H., Wilson, I.A. | 1.9 | X-RAY DIFFRACTION | 0.229 | 0.186 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7k93 | I | i | 0 | C | protein | null | non-structural protein 1 | VIRAL PROTEIN | 09/28/20 | DENV2 NS1 in complex with neutralizing 2B7 single chain Fab variable region (scFv) | DENGUE VIRUS 2; MUS MUSCULUS | mus musculus | null | dengue virus 2 | Akey, D.L., Smith, J.L. | 2.89 | X-RAY DIFFRACTION | 0.269 | 0.223 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7z1c | F | null | 0 | A | protein | null | spike protein s1 | ANTIVIRAL PROTEIN | 02/24/22 | Nanobody H11-B5 and H11-F2 bound to RBD | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Mikolajek, H., Naismith, J.H. | 1.9 | X-RAY DIFFRACTION | 0.199 | 0.175 | false | true | IGHV1 | null | null | null | null | null | null | null |
2bfv | H | L | 0 | H | Hapten | STG | ESTRIOL 3-(B-D-GLUCURONIDE) | IMMUNOGLOBULIN | 05/27/97 | MONOCLONAL ANTIBODY FRAGMENT FV4155 FROM E. COLI | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Trinh, C.H., Phillips, S.E.V. | 2.5 | X-RAY DIFFRACTION | unknown | 0.187 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
5ds8 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 09/17/15 | Context-independent anti-hypusine antibody FabHpu98 in complex with hypusine | ORYCTOLAGUS CUNICULUS; SYNTHETIC CONSTRUCT | oryctolagus cuniculus | oryctolagus cuniculus | null | Zhai, Q., Carter, P.J. | 1.95 | X-RAY DIFFRACTION | 0.224 | 0.183 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5dmj | E | null | 0 | D | protein | null | tumor necrosis factor receptor superfamily member 5 | IMMUNE SYSTEM/SIGNALING PROTEIN | 09/08/15 | Structure of the extracellular domain of the CD40 in complex with 3H56-5 DAB | HOMO SAPIENS | homo sapiens | null | homo sapiens | Sheriff, S. | 2.79 | X-RAY DIFFRACTION | 0.258 | 0.229 | false | true | IGHV3 | null | null | 0 | -11.290108 | SPR | null | TBD |
6nqd | G | H | 0 | F | E | protein | protein | NA | NA | t/f100 env gp41 | t/f100 env gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/21/19 | Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 Fab | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Fang, Q., Rossmann, M.G. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
5ocl | D | null | 0 | null | null | null | null | IMMUNE SYSTEM | 07/03/17 | Nanobody-anti-VGLUT nanobody complex | VICUGNA PACOS; LAMA GLAMA | lama glama | null | null | Dutzler, R., Schenck, S., Kunz, L. | 2.2 | X-RAY DIFFRACTION | 0.208 | 0.188 | false | true | IGHV1 | null | null | null | null | null | null | null |
7php | N | null | 0 | A | protein | null | multidrug resistance protein norm | MEMBRANE PROTEIN | 08/18/21 | Structure of Multidrug and Toxin Compound Extrusion (MATE) transporter NorM by NabFab-fiducial assisted cryo-EM | VIBRIO CHOLERAE RC385; SYNTHETIC CONSTRUCT; LAMA GLAMA | synthetic construct | null | vibrio cholerae rc385 | Bloch, J.S., Mukherjee, S., Kowal, J., Niederer, M., Pardon, E., Steyaert, J., Kossiakoff, A.A., Locher, K.P. | 3.47 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6do1 | E | null | 0 | A | protein | null | type-1 angiotensin ii receptor,soluble cytochrome b562 brilfusion protein | MEMBRANE PROTEIN | 06/08/18 | Structure of nanobody-stabilized angiotensin II type 1 receptor bound to S1I8 | HOMO SAPIENS; ESCHERICHIA COLI; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens, escherichia coli | Wingler, L.M., McMahon, C., Staus, D.P., Lefkowitz, R.J., Kruse, A.C. | 2.901 | X-RAY DIFFRACTION | 0.359 | 0.305 | false | true | IGHV1 | null | null | null | null | null | null | null |
1svz | b | B | 0 | D | peptide | null | epitope peptide corresponding to n-terminus ofhiv-2 protease | IMMUNE SYSTEM | 03/30/04 | Crystal structure of the single-chain Fv fragment 1696 in complex with the epitope peptide corresponding to N-terminus of HIV-2 protease | MUS MUSCULUS; SYNTHETIC CONSTRUCT | null | mus musculus | null | Rezacova, P., Brynda, J., Lescar, J., Bentley, G.A., Fabry, M., Horejsi, M., Sedlacek, J. | 1.89 | X-RAY DIFFRACTION | 0.239 | 0.196 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7lud | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/22/21 | Crystal structure of Fab ADI-14442 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Rush, S.A., McLellan, J.S. | 2.9 | X-RAY DIFFRACTION | 0.233 | 0.194 | false | true | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
6x87 | E | F | 0 | X | protein | null | circumsporozoite protein | IMMUNE SYSTEM | 06/01/20 | CryoEM structure of the Plasmodium berghei circumsporozoite protein in complex with inhibitory mouse antibody 3D11. | MUS MUSCULUS; PLASMODIUM BERGHEI | mus musculus | mus musculus | plasmodium berghei | Kucharska, I., Thai, E., Rubinstein, J., Julien, J.P. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6h0e | C | D | 0 | G | peptide | null | microtubule-associated protein tau | IMMUNE SYSTEM | 07/09/18 | FAB dmCBTAU-22.1 IN COMPLEX WITH TAU PEPTIDE V1088-23 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | mus musculus | Juraszek, J., Steinbacher, S. | 1.95 | X-RAY DIFFRACTION | 0.285 | 0.222 | false | true | IGHV1 | IGKV2 | Kappa | 0 | -9.031008 | Unknown | null | TBD |
1fl3 | A | B | 0 | A | Hapten | SPB | 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID | IMMUNE SYSTEM | 08/11/00 | CRYSTAL STRUCTURE OF THE BLUE FLUORESCENT ANTIBODY (19G2) IN COMPLEX WITH STILBENE HAPTEN AT 277K | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Stevens, R.C., Beuscher IV, A.E. | 2.45 | X-RAY DIFFRACTION | 0.262 | 0.231 | false | false | IGHV5 | IGKV2 | Kappa | 0 | -9.271239 | Unknown | null | TBD |
6gk4 | F | null | 0 | D | protein | null | cystic fibrosis transmembrane conductance regulator | HYDROLASE | 05/18/18 | Human NBD1 of CFTR in complex with nanobodies D12 and T8 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C. | 2.91 | X-RAY DIFFRACTION | 0.295 | 0.246 | false | true | IGHV1 | null | null | null | null | null | null | null |
5m94 | B | null | 0 | A | protein | null | divalent metal cation transporter mnth | TRANSPORT PROTEIN | 10/31/16 | Crystal structure of Staphylococcus capitis divalent metal ion transporter (DMT) in complex with nanobody | STAPHYLOCOCCUS CAPITIS; LAMA GLAMA | lama glama | null | staphylococcus capitis | Dutzler, R., Ehrnstorfer, I.A. | 3.101 | X-RAY DIFFRACTION | 0.273 | 0.237 | false | true | IGHV1 | null | null | null | null | null | null | null |
6q23 | H | L | 0 | A | protein | null | neuraminidase | VIRAL PROTEIN,HYDROLASE/IMMUNE SYSTEM | 08/06/19 | Crystal structure of human 1G01 Fab in complex with influenza virus neuraminidase from A/California/04/2009 (H1N1) | INFLUENZA A VIRUS (A/CALIFORNIA/04/2009 (H1N1); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/california/04/2009 (h1n1) | Zhu, X., Wilson, I.A. | 3.27 | X-RAY DIFFRACTION | 0.241 | 0.196 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4nyl | E | F | 0 | null | null | null | null | IMMUNE SYSTEM | 12/10/13 | Crystal structure of adalimumab FAB fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Fan, L.J., Lv, L.L., Zhang, Q.J., Chen, C.L. | 2.8 | X-RAY DIFFRACTION | 0.358 | 0.275 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7n28 | S | U | 0 | G | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM/VIRAL PROTEIN | 05/28/21 | Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J033 in complex with HIV-1 Env | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; MACACA MULATTA | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Gao, F. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
5y2k | G | H | 0 | null | null | null | null | IMMUNE SYSTEM | 07/26/17 | A human antibody AF4H1L1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Xiao, H., Qi, J., Gao, F.G. | 2.1 | X-RAY DIFFRACTION | 0.259 | 0.220 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
1ymh | D | C | 0 | F | protein | null | protein l | IMMUNE SYSTEM | 01/21/05 | anti-HCV Fab 19D9D6 complexed with protein L (PpL) mutant A66W | FINEGOLDIA MAGNA; MUS MUSCULUS | mus musculus | mus musculus | finegoldia magna | Granata, V., Housden, N.G., Harrison, S., Jolivet-Reynaud, C., Gore, M.G., Stura, E.A. | 2.6 | X-RAY DIFFRACTION | 0.302 | 0.224 | false | false | IGHV9 | IGKV8 | Kappa | null | null | null | null | null |
2xza | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/24/10 | Crystal Structure of recombinant A.17 antibody FAB fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Carletti, E., Nachon, F., Nicolet, Y., Masson, P., Kurkova, I., Smirnov, I., Friboulet, A., Tramontano, A., Gabibov, A. | 1.5 | X-RAY DIFFRACTION | 0.21095 | 0.16623 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
5lx9 | H | h | 0 | A | protein | null | human adiponectin receptor 2 | MEMBRANE PROTEIN | 09/20/16 | CRYSTAL STRUCTURE OF HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID AT 2.4 ANGSTROM RESOLUTION | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Vasiliauskaite-Brooks, I., Leyrat, C., Hoh, F., Granier, S. | 2.4 | X-RAY DIFFRACTION | 0.205 | 0.181 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7m74 | N | null | 0 | null | null | null | null | SIGNALING PROTEIN | 03/26/21 | ATP-bound AMP-activated protein kinase | HOMO SAPIENS; ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | null | Yan, Y., Mukherjee, S., Harikumar, K.G., Strutzenberg, T., Zhou, X.E., Powell, S.K., Xu, T., Sheldon, R., Lamp, J., Brunzelle, J.S., Radziwon, K., Ellis, A., Novick, S.J., Vega, I.E., Jones, R., Miller, L.J., Xu, H.E., Griffin, P.R., Kossiakoff, A.A., Melcher, K. | 3.93 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7qez | E | F | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 12/03/21 | Crystal structure of the SARS-CoV-2 RBD in complex with the ultrapotent antibody CV2.1169 and CR3022 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Fernandez, I., Rey, F.A. | 2.89 | X-RAY DIFFRACTION | 0.281 | 0.239 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
3zdx | H | L | 0 | A | D | protein | protein | NA | NA | integrin alpha-iib | integrin beta-3 | CELL ADHESION/IMMUNE SYSTEM | 12/03/12 | Integrin alphaIIB beta3 headpiece and RGD peptide complex | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | homo sapiens | Zhu, J.H., Zhu, J.Q., Springer, T.A. | 2.45 | X-RAY DIFFRACTION | 0.1971 | 0.1628 | false | true | IGHV14 | IGKV14 | Kappa | null | null | null | null | null |
2fl5 | H | L | 0 | H | Hapten | RBF | RIBOFLAVIN | IMMUNE SYSTEM | 01/05/06 | Cofactor-containing antibodies: Crystal structure of the original yellow antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Zhu, X., Wilson, I.A. | 3.0 | X-RAY DIFFRACTION | 0.290 | 0.240 | false | false | IGHV3 | IGLV3 | Lambda | 0 | -11.929943 | Unknown | null | TBD |
6dl8 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 05/31/18 | Crystal Structure of an influenza A hemagglutinin antibody Fab variant CH67:1203d4 chimera | HOMO SAPIENS | homo sapiens | homo sapiens | null | Dong, J., Finn, J.A., Crowe, J.E. | 3.805 | X-RAY DIFFRACTION | 0.284 | 0.233 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
2xxm | B | null | 0 | A | protein | null | capsid protein p24 | IMMUNE SYSTEM/PEPTIDE | 11/10/10 | Crystal structure of the HIV-1 capsid protein C-terminal domain in complex with a camelid VHH and the CAI peptide. | HUMAN IMMUNODEFICIENCY VIRUS; VICUGNA PACOS; SYNTHETIC CONSTRUCT | vicugna pacos | null | human immunodeficiency virus | Igonet, S., Vaney, M.-C., Bartonova, V., Helma, J., Rothbauer, U., Leonhardt, H., Stura, E., Krausslich, H.-G., Rey, F.A. | 1.65 | X-RAY DIFFRACTION | 0.2166 | 0.1923 | false | true | IGHV1 | null | null | null | null | null | null | null |
7ri2 | B | null | 0 | A | protein | null | glycoprotein 120 | IMMUNE SYSTEM | 07/19/21 | Crystal structure of anti-HIV llama VHH antibody A12 in complex with HIV-1 C1086 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; LAMA GLAMA | lama glama | null | human immunodeficiency virus 1 | Zhou, T., Kwong, P.D. | 2.8 | X-RAY DIFFRACTION | 0.330 | 0.273 | false | true | IGHV1 | null | null | null | null | null | null | null |
6b5r | H | L | 0 | A | peptide | null | pfcsp peptide 21asp-pro-asn | IMMUNE SYSTEM | 09/29/17 | Structure of PfCSP peptide 21 with human antibody CIS42 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Pancera, M., Weidle, C. | 1.775 | X-RAY DIFFRACTION | 0.237 | 0.191 | false | true | IGHV7 | IGLV2 | Lambda | 0 | -11.967304 | Unknown | null | TBD |
7lvw | L | null | 0 | C | protein | null | fusion glycoprotein f0 | IMMUNE SYSTEM/VIRAL PROTEIN | 02/26/21 | Structure of RSV F in Complex with VHH Cl184 | RESPIRATORY SYNCYTIAL VIRUS; LAMA GLAMA | lama glama | null | respiratory syncytial virus | Hsieh, C.-L., McLellan, J.S. | 2.1 | X-RAY DIFFRACTION | 0.230 | 0.201 | false | true | IGHV1 | null | null | null | null | null | null | null |
4o5i | O | P | 0 | C | protein | null | hemagglutinin ha1 chain | VIRAL PROTEIN/IMMUNE SYSTEM | 12/19/13 | Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Lee, P.S., Wilson, I.A. | 6.501 | X-RAY DIFFRACTION | 0.248 | 0.201 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5i6x | B | C | 0 | A | protein | null | sodium-dependent serotonin transporter | MEMBRANE PROTEIN | 02/16/16 | X-ray structure of the ts3 human serotonin transporter complexed with paroxetine at the central site | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Coleman, J.A., Green, E.M., Gouaux, E. | 3.14 | X-RAY DIFFRACTION | 0.270 | 0.238 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7t0j | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 11/29/21 | Crystal structure of S25-2 Fab Unliganded 3 | MUS MUSCULUS | mus musculus | mus musculus | null | Legg, M.S.G., Blackler, R.J., Evans, S.V. | 2.15 | X-RAY DIFFRACTION | 0.281 | 0.230 | false | true | IGHV7 | IGKV8 | Kappa | null | null | null | null | null |
6c5w | C | null | 0 | B | protein | null | calcium uniporter | MEMBRANE PROTEIN | 01/17/18 | Crystal structure of the mitochondrial calcium uniporter | METARHIZIUM ACRIDUM (STRAIN CQMA 102); ESCHERICHIA COLI K-12 | escherichia coli k-12 | null | metarhizium acridum (strain cqma 102) | Fan, C., Fan, M., Fastman, N., Zhang, J., Feng, L. | 3.1001 | X-RAY DIFFRACTION | 0.299 | 0.256 | false | true | IGHV1 | null | null | null | null | null | null | null |
6mfj | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/11/18 | Crystal structure of the ADCC potent antibody DH677.3 Fab elicited in the RV305 vaccine trial. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Young, B., Tolbert, W.D., Pazgier, M. | 2.62 | X-RAY DIFFRACTION | 0.261 | 0.199 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5f8r | C | null | 0 | A | protein | null | adhesin binding fucosylated histo-blood group antigen,adhesin,adhesin binding fucosylated histo-blood group antigen | CELL ADHESION | 12/09/15 | Blood group antigen binding adhesin BabA of Helicobacter pylori strain S831 in complex with blood group H Lewis b hexasaccharide | HELICOBACTER PYLORI; LAMA GLAMA | lama glama | null | helicobacter pylori | Moonens, K., Gideonsson, P., Subedi, S., Romao, E., Oscarson, S., Muyldermans, S., Boren, T., Remaut, H. | 2.44 | X-RAY DIFFRACTION | 0.219 | 0.189 | false | true | IGHV1 | null | null | null | null | null | null | null |
6id4 | H | L | 0 | A | B | protein | protein | NA | NA | mhc class i antigen | beta-2-microglobulin | IMMUNE SYSTEM | 09/08/18 | Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Lescar, J., Wong, Y.H., Liew, C.W., Gu, Y., MacAry, P.A. | 2.4 | X-RAY DIFFRACTION | 0.246 | 0.197 | false | true | IGHV1 | IGLV5 | Lambda | null | null | null | null | null |
7pbz | F | null | 0 | C | B | protein | protein | NA | NA | gamma-aminobutyric acid receptor subunit beta-3 | gamma-aminobutyric acid receptor subunit beta-3 | MEMBRANE PROTEIN | 08/03/21 | a1b3 GABA-A receptor + GABA + Zn2+ | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | homo sapiens | Miller, P.S., Kasaragod, V.B. | 2.79 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4g6f | H | L | 0 | P | peptide | null | gp41 mper peptide | IMMUNE SYSTEM | 07/19/12 | Crystal Structure of 10E8 Fab in Complex with an HIV-1 gp41 Peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ofek, G., Huang, J., Connors, M., Kwong, P.D. | 2.1 | X-RAY DIFFRACTION | 0.218 | 0.180 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -10.599564 | Unknown | null | TBD |
7wig | S | s | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | STRUCTURAL PROTEIN | 01/03/22 | Cryo-EM structure of the L-054,264-bound human SSTR2-Gi1 complex | HOMO SAPIENS; RATTUS NORVEGICUS; BOS TAURUS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | rattus norvegicus | Chen, L., Wang, W., Dong, Y., Shen, D., Guo, J., Qin, J., Zhang, H., Shen, Q., Zhang, Y., Mao, C. | 2.7 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
3uaj | H | L | 0 | A | protein | null | envelope protein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/21/11 | Crystal structure of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2 | DENGUE VIRUS 4; PAN TROGLODYTES | pan troglodytes | pan troglodytes | dengue virus 4 | Cockburn, J.J.B., Stura, E.A., Navarro-Sanchez, M.E., Rey, F.A. | 3.232 | X-RAY DIFFRACTION | 0.246 | 0.241 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -11.647373 | Unknown | null | TBD |
5bzd | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 06/11/15 | Crystal Structure of PCDN-27A, an antibody from the PCDN family of HIV-1 antibodies | HOMO SAPIENS | homo sapiens | homo sapiens | null | Garces, F., WILSON, I.A. | 2.7 | X-RAY DIFFRACTION | 0.247 | 0.211 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
6xvi | D | null | 0 | null | null | null | null | STRUCTURAL PROTEIN | 01/22/20 | Crystal structure of Megabody Mb-Nb207-c7HopQ_A12 | HELICOBACTER PYLORI (STRAIN G27); HELICOBACTER PYLORI G27 | helicobacter pylori (strain g27), helicobacterpylori g27 | null | null | Steyaert, J., Uchanski, T., Fischer, B. | 2.596 | X-RAY DIFFRACTION | 0.250 | 0.224 | false | true | IGHV1 | null | null | null | null | null | null | null |
6k6a | null | B | 0 | C | protein | null | engineered protein a | STRUCTURAL PROTEIN | 06/02/19 | Application of anti-helix antibodies in protein structure determination (8188cys-3LRHcys) | HOMO SAPIENS; STAPHYLOCOCCUS AUREUS | null | homo sapiens | staphylococcus aureus | Lee, J.O., Jin, M.S., Kim, J.W., Kim, S., Lee, H., Cho, G.Y. | 1.94 | X-RAY DIFFRACTION | 0.215 | 0.169 | false | true | null | IGLV1 | Lambda | null | null | null | null | null |
4gmt | I | M | 0 | null | null | null | null | IMMUNE SYSTEM | 08/16/12 | Crystal structure of heterosubtypic Fab S139/1 | MUS MUSCULUS | mus musculus | mus musculus | null | Lee, P.S., Ekiert, D.C., Wilson, I.A. | 2.05 | X-RAY DIFFRACTION | 0.209 | 0.158 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
6mwx | K | L | 0 | J | protein | null | e2 | VIRUS/IMMUNE SYSTEM | 10/30/18 | CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-69 Antibody | EASTERN EQUINE ENCEPHALITIS VIRUS; MUS MUSCULUS | mus musculus | mus musculus | eastern equine encephalitis virus | Hasan, S.S., Sun, C., Kim, A.S., Watanabe, Y., Chen, C.L., Klose, T., Buda, G., Crispin, M., Diamond, M.S., Klimstra, W.B., Rossmann, M.G. | 8.2 | ELECTRON MICROSCOPY | null | null | false | false | IGHV9 | IGLV1 | Lambda | null | null | null | null | null |
7zr7 | H | L | 0 | B | protein | null | spike glycoprotein,fibritin | STRUCTURAL PROTEIN | 05/03/22 | OMI-42 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; TEQUATROVIRUS T4; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2, tequatrovirus t4 | Duyvesteyn, H.M.E., Ren, J., Stuart, D.I. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
7s4g | A | B | 0 | K | peptide | null | lymphocyte antigen 6 complex locus protein g6d | SIGNALING PROTEIN | 09/08/21 | Fab fragment bound to the Cter peptide of Ly6G6D | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Rouge, L., Lupardus, P. | 2.2 | X-RAY DIFFRACTION | 0.235 | 0.192 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6zpl | E | null | 0 | B | protein | null | sodium- and chloride-dependent glycine transporter 1 | MEMBRANE PROTEIN | 07/08/20 | Inward-open structure of human glycine transporter 1 in complex with a benzoylisoindoline inhibitor, sybody Sb_GlyT1#7 and bound Na and Cl ions. | HOMO SAPIENS; HUNGATEICLOSTRIDIUM THERMOCELLUM (STRAIN ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372); UNIDENTIFIED | unidentified | null | homo sapiens | Shahsavar, A., Stohler, P., Bourenkov, G., Zimmermann, I., Siegrist, M., Guba, W., Pinard, E., Sinning, S., Seeger, M.A., Schneider, T.R., Dawson, R.J.P., Nissen, P. | 3.945 | X-RAY DIFFRACTION | 0.291 | 0.277 | false | true | IGHV1 | null | null | null | null | null | null | null |
7m6f | C | D | 0 | E | protein | null | spike glycoprotein | VIRAL PROTEIN/ANTIVIRAL PROTEIN | 03/25/21 | Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG1-22 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Barnes, C.O., Bjorkman, P.J. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
3nh7 | H | L | 0 | A | protein | null | bone morphogenetic protein receptor type-1a | IMMUNE SYSTEM | 06/14/10 | Crystal structure of the neutralizing Fab fragment AbD1556 bound to the BMP type I receptor IA | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Mueller, T.D., Harth, S., Sebald, W. | 2.7 | X-RAY DIFFRACTION | 0.280 | 0.234 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -10.5 | SPR | 25 | 20927405 |
7tca | D | E | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 12/23/21 | Cryo-EM structure of SARS-CoV-2 Omicron spike in complex with antibody A19-46.1 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, T., Kwong, P.D. | 3.85 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV8 | Lambda | null | null | null | null | null |
4lhq | D | null | 0 | C | protein | null | ricin | HYDROLASE/IMMUNE SYSTEM | 07/01/13 | Ricin A chain bound to camelid nanobody (VHH8) | RICINUS COMMUNIS; VICUGNA PACOS | vicugna pacos | null | ricinus communis | Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N. | 2.3 | X-RAY DIFFRACTION | 0.248 | 0.192 | false | true | IGHV1 | null | null | null | null | null | null | null |
7zmm | G | null | 0 | D | protein | null | atp-dependent dna helicase q5 | HYDROLASE | 04/19/22 | Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G2-001 | Homo sapiens; Lama glama | lama glama | null | homo sapiens | Ye, M., Makola, M., Newman, J.A., Fairhead, M., MacLean, E., Krojer, T., Aitkenhead, H., Bountra, C., Gileadi, O., von Delft, F. | 2.5 | X-RAY DIFFRACTION | 0.281 | 0.240 | false | true | IGHV1 | null | null | null | null | null | null | null |
5aze | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 10/02/15 | Fab fragment of calcium-dependent antigen binding antibody, 6RL#9 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Kadono, S., Hironiwa, N., Ishii, S., Igawa, T., Hattori, K. | 2.2 | X-RAY DIFFRACTION | 0.272 | 0.211 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7kh0 | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-3,isoform gnas-2 of guanine nucleotide-binding protein g(s) subunit alpha isoforms short fusion | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 10/19/20 | Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | homo sapiens | Wang, L., Xu, J., Gao, S., Sun, D., Liu, H., Liu, Z., Du, Y., Zhang, C. | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
5drn | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/20/16 | Context-independent anti-hypusine antibody FabHpu24 in complex with hypusine | ORYCTOLAGUS CUNICULUS | oryctolagus cuniculus | oryctolagus cuniculus | null | Zhai, Q., Carter, P.J. | 1.994 | X-RAY DIFFRACTION | 0.222 | 0.183 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4wuu | E | D | 0 | A | C | protein | peptide | NA | NA | hla class i histocompatibility antigen, a-2 alpha chain | arg-met-phe-pro-asn-ala-pro-tyr-leu | IMMUNE SYSTEM | 11/03/14 | Structure of ESK1 in complex with HLA-A*0201/WT1 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Ataie, N.J., Ng, H.L. | 3.047 | X-RAY DIFFRACTION | 0.254 | 0.198 | false | true | IGHV5 | IGLV1 | Lambda | 0 | -10.74946 | SPR | null | TBD |
6wtv | H | I | 0 | G | protein | null | reticulocyte binding protein 2b | CELL INVASION | 05/04/20 | Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 258259 | PLASMODIUM VIVAX (STRAIN SALVADOR I); HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium vivax (strain salvador i) | Chan, L.J., Dietrich, M.H., Tham, W.H. | 3.05 | X-RAY DIFFRACTION | 0.277 | 0.235 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
7whi | D | null | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 12/30/21 | The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | null | severe acute respiratory syndrome coronavirus2 | Zhan, W.Q., Zhang, X., Chen, Z.G., Sun, L. | 2.93 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7mfr | Y | X | 0 | Q | peptide | null | gly-gly-met | IMMUNE SYSTEM | 04/10/21 | Crystal Structure of a Fab fragment bound to peptide GGM | ORYCTOLAGUS CUNICULUS; SYNTHETIC CONSTRUCT | oryctolagus cuniculus | oryctolagus cuniculus | homo sapiens | Sudhamsu, J. | 2.848 | X-RAY DIFFRACTION | 0.260 | 0.211 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3u36 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 10/04/11 | Crystal Structure of PG9 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | McLellan, J.S., Kwong, P.D. | 3.281 | X-RAY DIFFRACTION | 0.249 | 0.214 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
6hjx | H | null | 0 | C | protein | null | cys-loop ligand-gated ion channel | MEMBRANE PROTEIN | 09/04/18 | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) 7'C pore mutant (L238C) in complex with nanobody 72 | DICKEYA CHRYSANTHEMI; LAMA GLAMA | lama glama | null | dickeya chrysanthemi | Spurny, R., Govaerts, C., Evans, G.L., Pardon, E., Steyaert, J., Ulens, C. | 2.5 | X-RAY DIFFRACTION | 0.245 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
6k2i | A | null | 15 | null | null | null | null | AFB1-BINDING PROTEIN | 05/14/19 | Solution structure of camelid nanobody Nb11 against aflatoxin B1 | VICUGNA PACOS | vicugna pacos | null | null | Nie, Y., Li, S.L., He, T., Zhu, J., Yang, Y.H. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
1tet | H | L | 0 | P | peptide | null | cholera toxin peptide 3 (ctp3) | IMMUNOGLOBULIN | 06/21/93 | CRYSTAL STRUCTURE OF AN ANTICHOLERA TOXIN PEPTIDE COMPLEX AT 2.3 ANGSTROMS | MUS MUSCULUS | mus musculus | mus musculus | null | Shoham, M. | 2.3 | X-RAY DIFFRACTION | unknown | 0.148 | false | false | IGHV9 | IGKV1 | Kappa | 0.000001 | -8.24 | Other | 23 | 7690406 |
7dx4 | H | L | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN | 01/18/21 | The structure of FC08 Fab-hA.CE2-RBD complex | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Cao, L., Wang, X. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7ra8 | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/30/21 | SARS-CoV-2 S glycoprotein in complex with S2X259 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Veesler, D., Tortorici, M.A., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5fv2 | B | null | 0 | V | protein | null | vascular endothelial growth factor | null | 02/02/16 | Crystal structure of hVEGF in complex with VH domain antibody | HOMO SAPIENS | homo sapiens | null | homo sapiens | Chung, C., Batuwangala, T. | 3.45 | X-RAY DIFFRACTION | 0.26270 | 0.21244 | false | true | IGHV3 | null | null | 0 | -15.203792 | SPR | null | TBD |
4gft | B | null | 0 | A | protein | null | myosin a tail domain interacting protein | protein binding, immune system | 08/03/12 | Malaria invasion machinery protein-Nanobody complex | PLASMODIUM FALCIPARUM 3D7; LAMA GLAMA | lama glama | null | plasmodium falciparum 3d7 | Khamrui, S., Turley, S., Pardon, E., Steyaert, J., Verlinde, C., Fan, E., Bergman, L.W., Hol, W.G.J. | 1.6 | X-RAY DIFFRACTION | 0.205 | 0.181 | false | true | IGHV1 | null | null | null | null | null | null | null |
7eh3 | A | null | 5 | null | null | null | null | IMMUNE SYSTEM | 03/28/21 | Structure of Nanobody Nb23 in solution using NMR spectroscopy | LAMA GLAMA | lama glama | null | null | Percipalle, M., Hunashal, Y., Esposito, G., Fogolari, F. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6xvi | C | null | 0 | null | null | null | null | STRUCTURAL PROTEIN | 01/22/20 | Crystal structure of Megabody Mb-Nb207-c7HopQ_A12 | HELICOBACTER PYLORI (STRAIN G27); HELICOBACTER PYLORI G27 | helicobacter pylori (strain g27), helicobacterpylori g27 | null | null | Steyaert, J., Uchanski, T., Fischer, B. | 2.596 | X-RAY DIFFRACTION | 0.250 | 0.224 | false | true | IGHV1 | null | null | null | null | null | null | null |
7l2c | H | L | 0 | A | protein | null | spike glycoprotein | IMMUNE SYSTEM/Viral Protein | 12/16/20 | Crystallographic structure of neutralizing antibody 2-51 in complex with SARS-CoV-2 spike N-terminal domain (NTD) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Cerutti, G., Reddem, E.R., Shapiro, L. | 3.65 | X-RAY DIFFRACTION | 0.272 | 0.216 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
5u3p | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 12/02/16 | Crystal Structure of DH511.4 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Nicely, N.I., Williams, L.D., Ofek, G., Haynes, B.F. | 1.5 | X-RAY DIFFRACTION | 0.211 | 0.188 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5ldn | H | L | 0 | A | protein | null | hexon protein,hexon capsid | VIRAL PROTEIN | 06/27/16 | A viral capsid:antibody complex | HUMAN ADENOVIRUS C SEROTYPE 5; HUMAN ADENOVIRUS 5; MUS MUSCULUS | mus musculus | mus musculus | human adenovirus c serotype 5, human adenovirus5 | James, L. | 2.7 | X-RAY DIFFRACTION | 0.223 | 0.164 | false | true | IGHV2 | IGKV6 | Kappa | null | null | null | null | null |
7l0n | A | B | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN/HYDROLASE | 12/11/20 | Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Snell, G., Czudnochowski, N., Dillen, J., Nix, J.C., Croll, T.I., Corti, D. | 2.78 | X-RAY DIFFRACTION | 0.325 | 0.290 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6opq | M | O | 0 | E | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/Immune System | 04/25/19 | CD4- and 17-bound HIV-1 Env B41 SOSIP frozen with LMNG | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ozorowski, G., Torres, J.L., Ward, A.B. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1rzi | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 12/24/03 | Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D. | 2.9 | X-RAY DIFFRACTION | 0.321 | 0.233 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3p9w | F | null | 0 | E | protein | null | vascular endothelial growth factor a | SIGNALING PROTEIN/IMMUNE SYSTEM | 10/18/10 | Crystal structure of an engineered human autonomous VH Domain in complex with VEGF | HOMO SAPIENS | homo sapiens | null | homo sapiens | Ma, X., Wiesmann, C. | 2.41 | X-RAY DIFFRACTION | 0.233 | 0.193 | false | true | IGHV3 | null | null | 0 | -10.635483 | SPR | null | TBD |
7shy | E | F | 0 | B | protein | null | ige fc | IMMUNE SYSTEM | 10/11/21 | IgE-Fc in complex with omalizumab scFv | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Pennington, L.F., Jardetzky, T.J., Kleinboelting, S. | 3.0 | X-RAY DIFFRACTION | 0.230 | 0.173 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2kqn | null | B | 2 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the AL-09 H87Y immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
1p84 | J | K | 0 | E | protein | null | ubiquinol-cytochrome c reductase iron-sulfursubunit | OXIDOREDUCTASE | 05/06/03 | HDBT inhibited Yeast Cytochrome bc1 Complex | MUS MUSCULUS; SACCHAROMYCES CEREVISIAE | mus musculus | mus musculus | saccharomyces cerevisiae | Palsdottir, H., Lojero, C.G., Trumpower, B.L., Hunte, C. | 2.5 | X-RAY DIFFRACTION | 0.252 | 0.228 | false | true | IGHV3 | IGKV10 | Kappa | null | null | null | null | null |
1c12 | B | A | 0 | A | Hapten | TRZ | TRAZEOLIDE | IMMUNE SYSTEM | 07/20/99 | INSIGHT IN ODORANT PERCEPTION: THE CRYSTAL STRUCTURE AND BINDING CHARACTERISTICS OF ANTIBODY FRAGMENTS DIRECTED AGAINST THE MUSK ODORANT TRASEOLIDE | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Langedijk, A.C., Spinelli, S., Anguille, C., Hermans, P., Nederlof, J., Butenandt, J., Honegger, A., Cambillau, C., Pluckthun, A. | 2.6 | X-RAY DIFFRACTION | 0.270 | 0.205 | false | true | IGHV3 | IGKV14 | Kappa | 0 | -11.57 | Other | 17 | 10525411 |
4h88 | H | L | 0 | A | protein | null | major prion protein | IMMUNE SYSTEM | 09/21/12 | Structure of POM1 FAB fragment complexed with mouse PrPc Fragment 120-230 | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Baral, P.K., Wieland, B., Swayampakula, M., James, M.N. | 1.9 | X-RAY DIFFRACTION | 0.234 | 0.199 | false | false | IGHV1 | IGKV5 | Kappa | 0 | -11.647373 | SPR | null | TBD |
3eyq | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 10/21/08 | Crystal structure of MJ5 Fab, a germline antibody variant of anti-human cytomegalovirus antibody 8f9 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Thomson, C.A., Bryson, S., McLean, G.R., Creagh, A.L., Pai, E.F., Schrader, J.W. | 2.4 | X-RAY DIFFRACTION | 0.270 | 0.250 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
5uoe | P | Q | 0 | C | protein | null | insulin-degrading enzyme | Hydrolase/Immune System | 01/31/17 | Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE) | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Liang, W.G., Bailey, L., Kossiakoff, T., Tang, W.J. | 3.8 | X-RAY DIFFRACTION | 0.270 | 0.220 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4nhg | D | B | 0 | null | null | null | null | IMMUNE SYSTEM | 11/05/13 | Crystal Structure of 2G12 IgG Dimer | HOMO SAPIENS | homo sapiens | homo sapiens | null | Wu, Y., West, Jr., A.P., Kim, H.J., Thornton, M.E., Ward, A.B., Bjorkman, P.J. | 8.001 | X-RAY DIFFRACTION | 0.369 | 0.359 | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
4u6v | H | L | 0 | A | protein | null | alpha-hemolysin | IMMUNE SYSTEM | 07/29/14 | Mechanisms of Neutralization of a Human Anti-Alpha Toxin Antibody | HOMO SAPIENS; STAPHYLOCOCCUS AUREUS SUBSP. AUREUS TCH60 | homo sapiens | homo sapiens | staphylococcus aureus subsp. aureus tch60 | Oganesyan, V.Y., Peng, L., Damschroder, M.M., Cheng, L., Sadowska, A., Tkaczyk, C., Sellman, B., Wu, H., Dall'Acqua, W.F. | 2.56 | X-RAY DIFFRACTION | 0.235 | 0.198 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -15.006685 | SPR | null | TBD |
4lgp | D | null | 0 | C | protein | null | ricin | HYDROLASE/IMMUNE SYSTEM | 06/28/13 | Ricin A chain bound to camelid nanobody (VHH1) | RICINUS COMMUNIS; VICUGNA PACOS | vicugna pacos | null | ricinus communis | Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N. | 2.4 | X-RAY DIFFRACTION | 0.281 | 0.225 | false | true | IGHV1 | null | null | null | null | null | null | null |
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