pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
4gw1 | D | C | 0 | null | null | null | null | Immune system | 08/31/12 | cQFD Meditope | MURINAE,HOMO SAPIENS; SYNTHETIC CONSTRUCT | murinae,homo sapiens | murinae,homo sapiens | null | Donaldson, J.M., Zer, C., Avery, K.N., Bzymek, K.P., Horne, D.A., Williams, J.C. | 2.24 | X-RAY DIFFRACTION | 0.226 | 0.182 | false | true | IGHV2 | IGKV5 | Kappa | 0 | -8.685503 | Unknown | null | TBD |
7lkg | D | E | 0 | F | peptide | null | circumsporozoite protein | IMMUNE SYSTEM/ANTIGEN | 02/02/21 | Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.151 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum 3d7 | Xu, K., Kwong, P.D. | 2.02 | X-RAY DIFFRACTION | 0.254 | 0.213 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6qx3 | O | null | 0 | A | B | protein | protein | NA | NA | polymerase acidic protein | rna-directed rna polymerase catalytic subunit | RNA BINDING PROTEIN | 03/07/19 | Influenza A virus (A/NT/60/1968) polymerase Hetermotrimer in complex with 3'5' cRNA promoter and Nb8205 | LAMA GLAMA; INFLUENZA A VIRUS (STRAIN A/HONG KONG/1/1968 H3N2); INFLUENZA A VIRUS (STRAIN A/NORTHERN TERRITORY/60/1968 H3N2); SYNTHETIC CONSTRUCT | lama glama | null | influenza a virus (strain a/northernterritory/60/1968 h3n2) | influenza a virus (strain a/hong kong/1/1968h3n2) | Carrique, L., Keown, J.R., Fan, H., Fodor, E., Grimes, J.M. | 3.79 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6hkg | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 09/06/18 | Structure of FISW84 Fab Fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Benton, D.J., Rosenthal, P.B. | 1.87 | X-RAY DIFFRACTION | 0.200 | 0.183 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6ce0 | D | E | 0 | B | protein | null | envelope glycoprotein gp160 | viral protein/immune system | 02/09/18 | Crystal structure of a HIV-1 clade B tier-3 isolate H078.14 UFO-BG Env trimer in complex with broadly neutralizing Fabs PGT124 and 35O22 at 4.6 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kumar, S., Sarkar, A., Wilson, I.A. | 4.602 | X-RAY DIFFRACTION | 0.341 | 0.313 | false | true | unknown | unknown | unknown | null | null | null | null | null |
5i1c | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/05/16 | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV3-20 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G. | 2.25 | X-RAY DIFFRACTION | 0.266 | 0.220 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7v3h | K | L | 0 | B | protein | null | envelope protein e | VIRUS/IMMUNE SYSTEM | 08/10/21 | DENV2_NGC_Fab_C10 28degrees (3Fab:3E) | DENGUE VIRUS TYPE 2 (STRAIN THAILAND/NGS-C/1944); HOMO SAPIENS | homo sapiens | homo sapiens | dengue virus type 2 (strain thailand/ngs-c/1944) | Shu, B., Zhang, S., Victor, A.K., Ng, T.S., Lok, S.M. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
5tdp | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 09/19/16 | Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces | HOMO SAPIENS | homo sapiens | homo sapiens | null | Yin, Y., Carter, P.J. | 1.716 | X-RAY DIFFRACTION | 0.252 | 0.220 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7kde | Q | R | 0 | C | protein | null | hiv-1 envelope glycoprotein bg505 sosip.664 gp41 | VIRAL PROTEIN/Immune System | 10/08/20 | BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Barnes, C.O., Bjorkman, P.J. | 3.55 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
4k9e | H | L | 0 | C | protein | null | mast/stem cell growth factor receptor kit | IMMUNE SYSTEM | 04/19/13 | Crystal structure of KIT D4D5 fragment in complex with anti-Kit antibodies Fab79D | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Resheynyak, A.V., Boggon, T.J., Lax, I., Schlessinger, J. | 2.7 | X-RAY DIFFRACTION | 0.282 | 0.247 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -15.271103 | SPR | null | TBD |
4lst | H | L | 0 | G | protein | null | envelope glycoprotein gp120 of hiv-1 clade c | viral protein/immune system | 07/23/13 | Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade C strain ZM176.66 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Moquin, S., Kwong, P.D. | 2.55 | X-RAY DIFFRACTION | 0.239 | 0.190 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6dwa | H | L | 0 | H | carbohydrate | HD4 | 4-O-[2-acetamido-2-deoxy-beta-D-glucopyranosyl]-1-O-phosphono-D-ribitol | IMMUNE SYSTEM | 06/26/18 | Structure of the 4497 Antibody Fab fragment bound to a Staphylococcus aureus wall techoic acid analog | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Fong, R., Lupardus, P.J. | 1.922 | X-RAY DIFFRACTION | 0.235 | 0.207 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6hxw | H | L | 0 | A | protein | null | 5'-nucleotidase | IMMUNE SYSTEM | 10/18/18 | structure of human CD73 in complex with antibody IPH53 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | synthetic construct | homo sapiens | Roussel, A., Amigues, B. | 2.78 | X-RAY DIFFRACTION | 0.232 | 0.192 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4uv4 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/04/14 | Crystal structure of anti-FPR Fpro0165 Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Douthwaite, J.A., Sridharan, S., Huntington, C., Marwood, R., Hammersley, J., Hakulinen, J.K., Ek, M., Sjogren, T., Rider, D., Privezentzev, C., Seaman, J.C., Cariuk, P., Knights, V., Young, J., Wilkinson, T., Sleeman, M., Finch, D.K., Lowe, D.C., Vaughan, T.J. | 3.08 | X-RAY DIFFRACTION | 0.2804 | 0.2427 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
7wpe | W | null | 0 | null | null | null | null | VIRAL PROTEIN | 01/23/22 | SARS-CoV-2 Omicron Variant S Trimer complexed with two JMB2002 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS; LAMA GLAMA | lama glama | null | null | Yin, W., Xu, Y., Xu, P., Cao, X., Wu, C., Gu, C., He, X., Wang, X., Huang, S., Yuan, Q., Wu, K., Hu, W., Huang, Z., Liu, J., Wang, Z., Jia, F., Xia, K., Liu, P., Wang, X., Song, B., Zheng, J., Jiang, H., Cheng, X., Jiang, Y., Deng, S.J., Xu, H.E. | 2.69 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7mta | H | L | 3 | G | protein | null | rhodopsin kinase grk1 | MEMBRANE, Signaling protein/Immune System | 05/13/21 | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab1 | BOS TAURUS; HOMO SAPIENS | homo sapiens | homo sapiens | bos taurus | Chen, Q., Chen, C.-L., Tesmer, J.J.G. | 4.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7lka | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/02/21 | Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Yuan, M., Zhu, X., Wilson, I.A., Wu, N.C. | 1.981 | X-RAY DIFFRACTION | 0.264 | 0.215 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5kaq | Q | R | 0 | A | protein | null | hemagglutinin | IMMUNE SYSTEM | 06/01/16 | Crystal structure of broadly neutralizing Influenza A antibody 31.a.83 in complex with Hemagglutinin Hong Kong 1968. | INFLUENZA A VIRUS (A/HONG KONG/1-4-MA21-1/1968(H3N2)) | influenza a virus (a/hong kong/1-4-ma21-1/1968(h3n2)) | influenza a virus (a/hong kong/1-4-ma21-1/1968(h3n2)) | influenza a virus (a/hong kong/1-4-ma21-1/1968(h3n2)) | Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D. | 3.514 | X-RAY DIFFRACTION | 0.313 | 0.270 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
2bob | A | B | 0 | C | protein | null | potassium channel kcsa | IMMUNE SYSTEM/TRANSPORT PROTEIN | 04/09/05 | Potassium channel KcsA-Fab complex in thallium with tetrabutylammonium (TBA) | STREPTOMYCES LIVIDANS; MUS MUSCULUS | mus musculus | mus musculus | streptomyces lividans | Lenaeus, M.J., Vamvouka, M., Focia, P.J., Gross, A. | 2.76 | X-RAY DIFFRACTION | 0.251 | 0.220 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
2ai0 | I | M | 0 | null | null | null | null | IMMUNE SYSTEM | 07/28/05 | Anti-Cocaine Antibody 7.5.21, Crystal Form III | MUS MUSCULUS | mus musculus | mus musculus | null | Pozharski, E., Hewagama, A., Shanafelt, A., Ringe, D., Petsko, G.A. | 2.2 | X-RAY DIFFRACTION | 0.279 | 0.222 | false | false | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7ps3 | H | L | 0 | null | null | null | null | VIRAL PROTEIN | 09/22/21 | Crystal structure of antibody Beta-32 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Zhou, D., Ren, J., Stuart, D.I. | 1.7 | X-RAY DIFFRACTION | 0.188 | 0.168 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1hzh | K | M | 0 | null | null | null | null | IMMUNE SYSTEM | 01/24/01 | CRYSTAL STRUCTURE OF THE INTACT HUMAN IGG B12 WITH BROAD AND POTENT ACTIVITY AGAINST PRIMARY HIV-1 ISOLATES: A TEMPLATE FOR HIV VACCINE DESIGN | HOMO SAPIENS | homo sapiens | homo sapiens | null | Saphire, E.O., Burton, D.R., Wilson, I.A. | 2.7 | X-RAY DIFFRACTION | 0.273 | 0.229 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3u79 | null | F | 0 | null | null | null | null | IMMUNE SYSTEM | 10/13/11 | AL-103 Y32F Y96F | HOMO SAPIENS | null | homo sapiens | null | DiCostanzo, A.C., Thompson, J.R., Ramirez-Alvarado, M. | 1.62 | X-RAY DIFFRACTION | 0.223 | 0.169 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
7rco | F | E | 0 | A | protein | null | transforming growth factor beta-2 | IMMUNE SYSTEM | 07/07/21 | Crystal structure of human TGF-beta-2 bound to 4A11.V2 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Yin, J., Lupardus, P.J., Sudhamsu, J. | 2.9 | X-RAY DIFFRACTION | 0.286 | 0.208 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3b2u | Q | R | 0 | P | protein | null | epidermal growth factor receptor | IMMUNE SYSTEM/TRANSFERASE | 10/19/07 | Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ferguson, K.M., Li, S., Kussie, P. | 2.58 | X-RAY DIFFRACTION | 0.291 | 0.227 | false | true | IGHV4 | IGKV3 | Kappa | 0 | -12.27 | SPR | 25 | 18275813 |
3sge | H | L | 0 | K | peptide | null | r13 peptide | IMMUNE SYSTEM | 06/14/11 | Crystal structure of mAb 17.2 in complex with R13 peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Pizarro, J.C., Boulot, G., Hontebeyrie, M., Bentley, G.A. | 1.89 | X-RAY DIFFRACTION | 0.211 | 0.179 | false | true | IGHV10 | IGKV1 | Kappa | null | null | null | null | null |
4r4b | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 08/19/14 | Crystal structure of the anti-hiv-1 antibody 2.2c | HOMO SAPIENS | homo sapiens | homo sapiens | null | McLellan, J.S., Acharya, P., Huang, C.-C., Robinson, J., Kwong, P.D. | 2.199 | X-RAY DIFFRACTION | 0.214 | 0.166 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6r8x | C | B | 0 | A | protein | null | coagulation factor xi | BLOOD CLOTTING | 04/10/19 | COAGULATION FACTOR XI CATALYTIC DOMAIN IN COMPLEX WITH FAB-PORTION OF MAA868 | HOMO SAPIENS; UNIDENTIFIED | unidentified | unidentified | homo sapiens | Schiering, N., Koch, A. | 2.04 | X-RAY DIFFRACTION | 0.282 | 0.220 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
1mak | null | A | 9 | null | null | null | null | IMMUNOGLOBULIN | 09/16/93 | SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN | MUS MUSCULUS | null | mus musculus | null | Constantine, K.L., Friedrichs, M.S., Metzler, W.J., Wittekind, M., Hensley, P., Mueller, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
6pci | P | S | 0 | C | F | protein | protein | NA | NA | virion spike glycoprotein | virion spike glycoprotein,virion spike glycoprotein,ebolavirus (makona) gp2 | immune system, viral protein | 06/17/19 | EBOV GPdMuc (Makona) in complex with rEBOV-520 and rEBOV-548 Fabs | EBOLA VIRUS; HOMO SAPIENS; ZAIRE EBOLAVIRUS | homo sapiens | homo sapiens | ebola virus | zaire ebolavirus, ebola virus | Ward, A.B., Murin, C.D., Alkutkar, T. | 4.12 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
6jhq | D | E | 0 | C | protein | null | vp3 | VIRUS | 02/18/19 | The cryo-EM structure of HAV bound to a neutralizing antibody-F4 | HUMAN HEPATITIS A VIRUS HU/AUSTRALIA/HM175/1976; MUS MUSCULUS | mus musculus | mus musculus | human hepatitis a virushu/australia/hm175/1976 | Cao, L., Liu, P., Yang, P., Gao, Q., Li, H., Sun, Y., Zhu, L., Lin, J., Su, D., Rao, Z., Wang, X. | 3.9 | ELECTRON MICROSCOPY | null | null | false | false | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7l1v | H | h | 0 | A | B | protein | protein | NA | NA | engineered guanine nucleotide-binding protein subunitalpha | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 12/15/20 | Orexin Receptor 2 (OX2R) in Complex with G Protein and Small-Molecule Agonist Compound 1 | HOMO SAPIENS; MUS MUSCULUS; LAMA GLAMA | mus musculus | null | homo sapiens | homo sapiens | Hong, C., Byrne, N.J., Zamlynny, B., Tummala, S., Xiao, L., Shipman, J.M., Partridge, A.T., Minnick, C., Breslin, M.J., Rudd, M.T., Stachel, S.J., Rada, V.L., Kern, J.C., Armacost, K.A., Hollingsworth, S.A., O'Brien, J.A., Hall, D.L., McDonald, T.P., Strickland, C., Brooun, A., Soisson, S.M., Hollenstein, K. | 3 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
5vm4 | I | null | 0 | null | null | null | null | UNKNOWN FUNCTION | 04/26/17 | The apo form of the triclocarban-binding single domain camelid nanobody VHH T10 | LAMA GLAMA | lama glama | null | null | Tabares-da Rosa, S., Gonzalez-Sapienza, G., Wilson, D.K. | 1.9 | X-RAY DIFFRACTION | 0.241 | 0.197 | false | true | unknown | unknown | unknown | null | null | null | null | null |
7rm0 | A | B | 0 | P | peptide | null | peptide from circumsporozoite protein variant vk247 | ANTIMICROBIAL PROTEIN | 07/26/21 | Antibody 2E10.E9 in complex with P. vivax CSP peptide ANGAGNQPGANGAGNQPG | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium vivax | Kucharska, I., Ivanochko, D., Julien, J.P. | 2.71 | X-RAY DIFFRACTION | 0.246 | 0.209 | false | true | IGHV9 | IGKV8 | Kappa | null | null | null | null | null |
1l7i | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/15/02 | Crystal Structure of the anti-ErbB2 Fab2C4 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Vajdos, F.F., Adams, C.W., Breece, T.N., Presta, L.G., de Vos, A.M., Sidhu, S.S. | 1.8 | X-RAY DIFFRACTION | 0.230 | 0.197 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3eyu | H | L | 0 | Q | peptide | null | ror2(518-525) peptide | IMMUNE SYSTEM | 10/21/08 | PFA1 Fab fragment complexed with Ror2(518-525) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Gardberg, A.S., Dealwis, C.G. | 2.71 | X-RAY DIFFRACTION | 0.248 | 0.177 | false | true | IGHV8 | IGKV1 | Kappa | 0 | -10.21 | SPR | 20 | 19385664 |
6fxn | O | P | 0 | L | protein | null | tumor necrosis factor ligand superfamily member 13b | IMMUNE SYSTEM | 03/09/18 | Crystal structure of human BAFF in complex with Fab fragment of anti-BAFF antibody belimumab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Lammens, A., Maskos, K., Willen, L., Jiang, X., Schneider, P. | 2.9 | X-RAY DIFFRACTION | 0.231 | 0.191 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
6ogx | C | D | 0 | G | protein | null | tumor necrosis factor receptor superfamily member 4 | IMMUNE SYSTEM | 04/03/19 | Ternary complex of OX40R (TNFRSF4) bound to Fab1 and Fab2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ultsch, M.H., Boenig, G., Harris, S.F. | 2.77 | X-RAY DIFFRACTION | 0.254 | 0.203 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6t3j | A | B | 0 | E | protein | null | tumor necrosis factor receptor superfamily member 10b | APOPTOSIS | 10/11/19 | Dual Epitope Targeting by Anti-DR5 Antibodies | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Tauchert, M.J., Augustin, M., Krapp, S., Overdijk, M.B., Breij, E.C.W., Hibbert, R.G. | 3.05 | X-RAY DIFFRACTION | 0.282 | 0.251 | false | true | IGHV14 | IGKV3 | Kappa | null | null | null | null | null |
4r96 | D | C | 0 | null | null | null | null | Immune System | 09/03/14 | Structure of a Llama Glama Fab 48A2 against human cMet | LLAMA GLAMA | lama glama | lama glama | null | Klarenbeek, A., El Mazouari, K., Desmyter, A., Blanchetot, C., Hultberg, A., Roovers, R.C., Cambillau, C., Spinelli, S., Del-Favero, J., Verrips, T., de Haard, H., Achour, I. | 3.31 | X-RAY DIFFRACTION | 0.261 | 0.217 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
7wpf | U | V | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 01/23/22 | SARS-CoV-2 Omicron Variant S Trimer complexed with three JMB2002 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS; LAMA GLAMA | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Yin, W., Xu, Y., Xu, P., Cao, X., Wu, C., Gu, C., He, X., Wang, X., Huang, S., Yuan, Q., Wu, K., Hu, W., Huang, Z., Liu, J., Wang, Z., Jia, F., Xia, K., Liu, P., Wang, X., Song, B., Zheng, J., Jiang, H., Cheng, X., Jiang, Y., Deng, S.J., Xu, H.E. | 2.92 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7c61 | H | L | 0 | A | protein | null | 5-hydroxytryptamine receptor 1b,soluble cytochrome b562,5-hydroxytryptamine receptor 1b | SIGNALING PROTEIN | 05/21/20 | Crystal structure of 5-HT1B-BRIL and SRP2070_Fab complex | MUS MUSCULUS; HOMO SAPIENS; ESCHERICHIA COLI | mus musculus | mus musculus | homo sapiens, escherichia coli | Suzuki, M., Miyagi, H., Asada, H., Yasunaga, M., Suno, C., Takahashi, Y., Saito, J., Iwata, S. | 3.0 | X-RAY DIFFRACTION | 0.290 | 0.252 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
6tcn | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 11/06/19 | Crystal structure of the omalizumab Fab - crystal form II | HOMO SAPIENS | homo sapiens | homo sapiens | null | Mitropoulou, A.N., Ceska, T., Beavil, A.J., Henry, A.J., McDonnell, J.M., Sutton, B.J., Davies, A.M. | 2.3 | X-RAY DIFFRACTION | 0.226 | 0.188 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5ilt | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/04/16 | Crystal structure of bovine Fab A01 | BOS TAURUS | bos taurus | bos taurus | null | Stanfield, R.L., Wilson, I.A. | 2.0 | X-RAY DIFFRACTION | 0.254 | 0.212 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7rta | H | L | 0 | N | peptide | null | neuropeptide y | HORMONE/IMMUNE SYSTEM | 08/12/21 | Crystal structures of human PYY and NPY | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Langley, D.B., Christ, D. | 2.6 | X-RAY DIFFRACTION | 0.270 | 0.217 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7v0v | A | null | 15 | null | null | null | null | IMMUNE SYSTEM | 05/11/22 | GFP Nanobody NMR Structure | SYNTHETIC CONSTRUCT | synthetic construct | null | null | Mueller, G.A. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3iy4 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 04/09/09 | Variable domains of the computer generated model (WAM) of Fab 15 fitted into the cryoEM reconstruction of the virus-Fab 15 complex | MUS MUSCULUS | mus musculus | mus musculus | null | Hafenstein, S., Bowman, V.D., Sun, T., Nelson, C.D., Palermo, L.M., Chipman, P.R., Battisti, A.J., Parrish, C.R., Rossmann, M.G. | 11.7 | ELECTRON MICROSCOPY | null | null | false | false | IGHV9 | IGKV3 | Kappa | null | null | null | null | null |
7ej4 | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 04/01/21 | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-25 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yang, T.J., Yu, P.Y., Wu, H.C., Hsu, S.T.D. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
5ush | D | E | 0 | A | protein | null | imv membrane protein | VIRAL PROTEIN/Immune system | 02/13/17 | Structure of vaccinia virus D8 protein bound to human Fab vv66 | VACCINIA VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | vaccinia virus | Zajonc, D.M. | 2.3 | X-RAY DIFFRACTION | 0.257 | 0.218 | false | false | IGHV4 | IGLV1 | Lambda | 0 | -12.037965 | SPR | null | TBD |
7nft | D | null | 0 | B | protein | null | polymerase basic protein 2 | VIRAL PROTEIN | 02/07/21 | Fujian capbinding domain in complex with Nb8208 | INFLUENZA A VIRUS (A/DUCK/FUJIAN/13/2002(H5N1)); HOMO SAPIENS | homo sapiens | null | influenza a virus (a/duck/fujian/13/2002(h5n1)) | Keown, J.R., Grimes, J.M., Fodor, E. | 3.14 | X-RAY DIFFRACTION | 0.291 | 0.244 | false | true | IGHV1 | null | null | null | null | null | null | null |
6zlr | B | C | 0 | A | protein | null | unknown | VIRAL PROTEIN | 07/01/20 | Soaking competent crystal form of the SARS-CoV-2 Receptor Binding Domain (RBD):CR3022 complex. | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | null | null | null | de Nicola, G.F., Nichols, C.E. | 3.1 | X-RAY DIFFRACTION | 0.247 | 0.218 | false | false | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6ywd | A | B | 0 | C | protein | null | de novo designed protein 4h_01 | DE NOVO PROTEIN | 04/29/20 | De novo designed protein 4H_01 in complex with Mota antibody | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | synthetic construct | Yang, C., Sesterhenn, F., Pojer, F., Correia, B.E. | 3.2 | X-RAY DIFFRACTION | 0.247 | 0.206 | false | true | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
3cm9 | A | L | 2 | null | null | null | null | IMMUNE SYSTEM | 03/21/08 | Solution Structure of Human SIgA2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7ce2 | Z | B | 0 | A | protein | null | tetanus toxin | HYDROLASE | 06/21/20 | The Crystal structure of TeNT Hc complexed with neutralizing antibody | CLOSTRIDIUM TETANI; HOMO SAPIENS | homo sapiens | homo sapiens | clostridium tetani | Wang, X., Wang, Y., Wu, C., Yu, J., Liao, H. | 2.01 | X-RAY DIFFRACTION | 0.218 | 0.180 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
7xod | null | S | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 05/01/22 | SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with three JMB2002 Fab Bound | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS; LAMA GLAMA | null | homo sapiens | severe acute respiratory syndrome coronavirus2 | Xu, Y., Wu, C., Liu, H., Yin, W., Xu, H.E. | 3.27 | ELECTRON MICROSCOPY | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
5ukr | H | L | 0 | G | protein | null | chimeric b.yu2 gp120 core derived from hiv-1 env | IMMUNE SYSTEM | 01/23/17 | Structure of unliganded anti-gp120 CD4bs antibody DH522.2 Fab in complex with a gp120 core | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1 | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Nicely, N.I. | 2.712 | X-RAY DIFFRACTION | 0.265 | 0.201 | false | true | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
7pi3 | K | L | 0 | H | protein | null | cysteine-rich protective antigen | IMMUNE SYSTEM | 08/19/21 | PfCyRPA bound to Fab fragments from monoclonal antibodies Cy.003, Cy.004 and Cy.007 | PLASMODIUM FALCIPARUM 3D7; GALLUS GALLUS | gallus gallus | gallus gallus | plasmodium falciparum 3d7 | Ragotte, R.J., Higgins, M.K. | 3.269 | X-RAY DIFFRACTION | 0.298 | 0.285 | false | true | unknown | unknown | unknown | null | null | null | null | null |
3pnw | Q | P | 0 | R | protein | null | tudor domain-containing protein 3 | PROTEIN BINDING/IMMUNE SYSTEM | 11/19/10 | Crystal Structure of the tudor domain of human TDRD3 in complex with an anti-TDRD3 FAB | HOMO SAPIENS, SYNTHETIC CONSTRUCT; HOMO SAPIENS | synthetic | synthetic | homo sapiens | Loppnau, P., Tempel, W., Wernimont, A.K., Lam, R., Ravichandran, M., Adams-Cioaba, M.A., Persson, H., Sidhu, S.S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Cossar, D., Structural Genomics Consortium (SGC) | 2.05 | X-RAY DIFFRACTION | 0.264 | 0.223 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5hi3 | C | D | 0 | A | protein | null | interleukin-17a | IMMUNE SYSTEM/INHIBITOR | 01/11/16 | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Liu, S. | 2.15 | X-RAY DIFFRACTION | 0.231 | 0.197 | false | true | IGHV3 | IGLV6 | Lambda | null | null | null | null | null |
6dcw | H | L | 0 | T | peptide | null | microtubule-associated protein | IMMUNE SYSTEM | 05/08/18 | Crystal structure of human anti-tau antibody CBTAU-27.1 Fab in complex with a human tau peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | colobus angolensis palliatus | Zhu, X., Zhang, H., Wilson, I.A. | 2.0 | X-RAY DIFFRACTION | 0.216 | 0.168 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6b9y | B | A | 0 | C | E | protein | protein | NA | NA | immunoglobulin g binding protein a | protein l | IMMUNE SYSTEM | 10/11/17 | Trastuzumab Fab v3 in complex with 5-phenyl meditope variant | HOMO SAPIENS; FINEGOLDIA MAGNA; STAPHYLOCOCCUS AUREUS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | staphylococcus aureus | finegoldia magna | Bzymek, K.P., King, J.D., Williams, J.C. | 2.14 | X-RAY DIFFRACTION | 0.218 | 0.171 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2ltq | F | E | 8 | D | protein | null | disulfide bond formation protein b | MEMBRANE PROTEIN, OXIDOREDUCTASE | 05/30/12 | High resolution structure of DsbB C41S by joint calculation with solid-state NMR and X-ray data | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Tang, M., Sperling, L.J., Schwieters, C.D., Nesbitt, A.E., Gennis, R.B., Rienstra, C.M. | NOT | SOLID-STATE NMR | null | null | false | false | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
7czp | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 09/09/20 | S protein of SARS-CoV-2 in complex bound with P2B-1A1 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yan, R.H., Zhang, Y.Y., Li, Y.N., Zhou, Q. | 3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
4xp6 | H | L | 0 | A | protein | null | transporter | tranport protein/inhibitor | 01/16/15 | X-ray structure of Drosophila dopamine transporter bound to psychostimulant methamphetamine | DROSOPHILA MELANOGASTER; MUS MUSCULUS | mus musculus | mus musculus | drosophila melanogaster | Aravind, P., Wang, K., Gouaux, E. | 3.1 | X-RAY DIFFRACTION | 0.259 | 0.236 | false | false | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
5yoy | H | E | 0 | C | protein | null | tumor necrosis factor | IMMUNE SYSTEM | 10/31/17 | Crystal structure of the human tumor necrosis factor in complex with golimumab Fv | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ono, M., Horita, S., Sato, Y., Nomura, Y., Iwata, S., Nomura, N. | 2.727 | X-RAY DIFFRACTION | 0.234 | 0.190 | false | true | IGHV3 | IGKV3 | Kappa | 0 | -14.658431 | Unknown | null | TBD |
1g9e | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 11/23/00 | SOLUTION STRUCTURE AND RELAXATION MEASUREMENTS OF AN ANTIGEN-FREE HEAVY CHAIN VARIABLE DOMAIN (VHH) FROM LLAMA | LAMA GLAMA | lama glama | null | null | Renisio, J.-G., Perez, J., Czisch, M., Guenneugues, M., Bornet, O., Frenken, L., Cambillau, C., Darbon, H. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
1mlc | D | C | 0 | F | protein | null | hen egg white lysozyme | COMPLEX (ANTIBODY/ANTIGEN) | 03/10/95 | MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME COMPLEXED WITH LYSOZYME | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | gallus gallus | Braden, B.C., Souchon, H., Eisele, J.-L., Bentley, G.A., Bhat, T.N., Navaza, J., Poljak, R.J. | 2.5 | X-RAY DIFFRACTION | 0.282 | unknown | false | true | IGHV1 | IGKV5 | Kappa | 0 | -9.6 | SPR | 25 | 10229844 |
6ayz | R | C | 0 | M | protein | null | histone chaperone asf1 | IMMUNE SYSTEM | 09/08/17 | Crystal structure of Asf1-Fab 12E complex | HOMO SAPIENS; SACCHAROMYCES CEREVISIAE (STRAIN ATCC 204508 / S288C) | homo sapiens | homo sapiens | saccharomyces cerevisiae (strain atcc 204508 /s288c) | Bailey, L.J., Kossiakoff, A.A. | 2.096 | X-RAY DIFFRACTION | 0.236 | 0.191 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1egj | H | L | 0 | A | protein | null | cytokine receptor common beta chain precursor | IMMUNE SYSTEM | 02/15/00 | DOMAIN 4 OF THE BETA COMMON CHAIN IN COMPLEX WITH AN ANTIBODY | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Rossjohn, J., McKinstry, W.J., Woodcock, J.M., McClure, B.J., Hercus, T.R., Parker, M.W., Lopez, A.F., Bagley, C.J. | 2.8 | X-RAY DIFFRACTION | 0.288 | 0.228 | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3uyp | A | a | 0 | B | protein | null | envelope protein | IMMUNE SYSTEM | 12/06/11 | Crystal structure of the dengue virus serotype 4 envelope protein domain III in complex with the variable domains of Mab 4E11 | MUS MUSCULUS; DENGUE VIRUS 4 | mus musculus | null | dengue virus 4 | Cockburn, J.J.B., Navarro Sanchez, M.E., Fretes, N., Urvoas, A., Staropoli, I., Kikuti, C.M., Coffey, L.L., Arenzana Seisdedos, F., Bedouelle, H., Rey, F.A. | 2.0 | X-RAY DIFFRACTION | 0.201 | 0.181 | true | true | unknown | unknown | unknown | 0.000004 | -7.349478 | ELISA | null | TBD |
1jto | B | null | 0 | M | protein | null | lysozyme | Antibody,Hydrolase | 08/21/01 | Degenerate interfaces in antigen-antibody complexes | CAMELUS DROMEDARIUS; GALLUS GALLUS | camelus dromedarius | null | gallus gallus | Decanniere, K., Transue, T.R., Desmyter, A., Maes, D., Muyldermans, S., Wyns, L. | 2.5 | X-RAY DIFFRACTION | 0.240 | 0.173 | false | true | IGHV1 | null | null | null | null | null | null | null |
2qr0 | L | K | 0 | I | protein | null | vascular endothelial growth factor a | IMMUNE SYSTEM | 07/27/07 | Structure of VEGF complexed to a Fab containing TYR and SER in the CDRs | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wiesmann, C. | 3.5 | X-RAY DIFFRACTION | 0.312 | 0.291 | false | false | IGHV3 | IGKV1 | Kappa | 0 | -11.5 | SPR | 37 | 17825836 |
6xja | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/23/20 | Streptococcus Pneumoniae IgA1 Protease with IgA1 substrate | STREPTOCOCCUS PNEUMONIAE (STRAIN ATCC BAA-255 / R6); HOMO SAPIENS | homo sapiens | homo sapiens | null | Eisenmesser, E.Z., Zheng, H. | 4 | ELECTRON MICROSCOPY | null | null | false | false | unknown | unknown | unknown | null | null | null | null | null |
7jo8 | null | A | 0 | null | null | null | null | IMMUNE SYSTEM | 08/06/20 | Crystal structure of a Chimeric Antigen Receptor (CAR) scFv domain rearrangement forming a VL-VL dimer | SYNTHETIC CONSTRUCT | null | synthetic construct | null | Cheung, J., Hendrickson, W.A., Kochenderfer, J.N., Youkharibache, P. | 1.399 | X-RAY DIFFRACTION | 0.171 | 0.155 | true | true | null | IGKV3 | Kappa | null | null | null | null | null |
6t2j | B | null | 0 | null | null | null | null | IMMUNE SYSTEM | 10/08/19 | dAb3 | SYNTHETIC CONSTRUCT | synthetic construct | null | null | Tsai, Y.-C.I., House, D., Rittinger, K. | 1.7 | X-RAY DIFFRACTION | 0.208 | 0.175 | false | true | IGHV3 | null | null | null | null | null | null | null |
7lmo | null | B | 0 | B | Hapten | NYO | (5~{R})-3-[2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl]-7-(1~{H}-imidazol-4-ylcarbonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione | IMMUNE SYSTEM | 02/05/21 | Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 34 [3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-7-(1H-imidazole-5-carbonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione] | HOMO SAPIENS | null | homo sapiens | homo sapiens | Yan, N.L., Wilson, I.A., Kelly, J.W. | 1.99 | X-RAY DIFFRACTION | 0.225 | 0.176 | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
6pzf | H | L | 0 | A | protein | null | neuraminidase | IMMUNE SYSTEM | 07/31/19 | Crystal structure of human NA-63 Fab in complex with neuraminidase from A/Hunan/02650/2016(H7N9) | INFLUENZA A VIRUS (A/HUNAN/02650/2016(H7N9); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/hunan/02650/2016(h7n9) | Zhu, X., Wilson, I.A. | 2.8 | X-RAY DIFFRACTION | 0.249 | 0.203 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6mph | M | N | 0 | C | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN | 10/06/18 | Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Kwong, P.D. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
4zto | H | L | 0 | P | peptide | null | epitope of rabbit monoclonal antibody r53 | IMMUNE SYSTEM | 05/14/15 | Fab/epitope complex structure of rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region | ORYCTOLAGUS CUNICULUS; SYNTHETIC CONSTRUCT | oryctolagus cuniculus | oryctolagus cuniculus | human immunodeficiency virus 1 | Pan, R., Kong, X.-P. | 2.3 | X-RAY DIFFRACTION | 0.223 | 0.167 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4g6j | H | L | 0 | A | protein | null | interleukin-1 beta | IMMUNE SYSTEM | 07/19/12 | Crystal structure of human IL-1beta in complex with the therapeutic antibody binding fragment of canakinumab | null | homo sapiens | homo sapiens | homo sapiens | Blech, M., Hoerer, S. | 2.03 | X-RAY DIFFRACTION | 0.252 | 0.226 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -11.44221 | SPR | null | TBD |
6xox | N | null | 0 | A | B | protein | protein | NA | NA | alpha subunit of gs with n-terminus swapped with equivalentresidues in gi,guanine nucleotide-binding protein g(s) subunit alpha isoforms xlas | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 07/07/20 | cryo-EM of human GLP-1R bound to non-peptide agonist LY3502970 | HOMO SAPIENS; MUS MUSCULUS; LAMA GLAMA | lama glama | null | homo sapiens | homo sapiens | Sun, B., Kobilka, B.K., Sloop, K.W., Feng, D., Kobilka, T.S. | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6xxn | D | null | 0 | null | null | null | null | ANTITUMOR PROTEIN | 06/10/20 | Crystal structure of NB7, a nanobody targeting prostate specific membrane antigen | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Shahar, A., Rosenfeld, L., Papo, N. | 2.65 | X-RAY DIFFRACTION | 0.231 | 0.182 | false | true | IGHV1 | null | null | null | null | null | null | null |
5w9k | E | F | 0 | D | protein | null | spike glycoprotein | VIRAL PROTEIN | 06/23/17 | MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4 | MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | middle east respiratory syndrome-relatedcoronavirus | Pallesen, J., Ward, A.B. | 4.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5ibu | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/22/16 | 6652 Fab (unbound) | HOMO SAPIENS | homo sapiens | homo sapiens | null | Raymond, D.D., Harrison, S.C. | 1.71 | X-RAY DIFFRACTION | 0.245 | 0.210 | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
5f6h | K | L | 0 | null | null | null | null | IMMUNE SYSTEM | 12/06/15 | Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque | HOMO SAPIENS | homo sapiens | homo sapiens | null | Fera, D., Harrison, S.C. | 2.66 | X-RAY DIFFRACTION | 0.262 | 0.230 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
2qad | D | C | 0 | A | protein | null | envelope glycoprotein gp160 | viral protein/immune system | 06/14/07 | Structure of tyrosine-sulfated 412d antibody complexed with HIV-1 YU2 gp120 and CD4 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Huang, C.-C., Tang, M., Robinson, J., Wyatt, R., Kwong, P.D. | 3.3 | X-RAY DIFFRACTION | 0.269 | 0.202 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6uup | C | c | 0 | null | null | null | null | ANTITUMOR PROTEIN | 10/31/19 | Structure of anti-hCD33 conditional scFv | CAMELIDAE MIXED LIBRARY | camelidae mixed library | null | null | Kimberlin, C.R., Park, S. | 2.20002 | X-RAY DIFFRACTION | 0.237 | 0.197 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6ssi | J | null | 0 | E | protein | null | cys-loop ligand-gated ion channel | TRANSPORT PROTEIN | 09/07/19 | Structure of the pentameric ligand-gated ion channel ELIC in complex with a PAM nanobody | DICKEYA CHRYSANTHEMI; LAMA GLAMA | lama glama | null | dickeya chrysanthemi | Ulens, C., Brams, M., Evans, G.L., Spurny, R., Govaerts, C., Pardon, E., Steyaert, J. | 2.59 | X-RAY DIFFRACTION | 0.246 | 0.230 | false | true | IGHV1 | null | null | null | null | null | null | null |
6y54 | M | N | 0 | N | unknown | OAB | unknown | IMMUNE SYSTEM | 02/24/20 | Crystal structure of a Neisseria meningitidis serogroup A capsular oligosaccharide bound to a functional Fab | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Dello Iacono, L., Henriques, P., Adamo, R. | 2.67 | X-RAY DIFFRACTION | 0.267 | 0.210 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
2mkw | null | A | 16 | null | null | null | null | IMMUNE SYSTEM | 02/13/14 | Solution Structure of 6aJl2 and 6aJL2-R24G Amyloidogenics Light Chain Proteins | HOMO SAPIENS | null | homo sapiens | null | Amero, C., Maya-Martinez, R.C., Gil-Rodriguez, P.C. | NOT | SOLUTION NMR | null | null | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
7luc | D | E | 0 | C | protein | null | fusion glycoprotein f0 | IMMUNE SYSTEM/VIRAL PROTEIN | 02/22/21 | Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B | RESPIRATORY SYNCYTIAL VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | respiratory syncytial virus | Wrapp, D., McLellan, J.S. | 3.21 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
2kh2 | B | b | 30 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
5usl | H | L | 0 | X | protein | null | imv membrane protein | VIRAL PROTEIN/Immune System | 02/13/17 | Structure of vaccinia virus D8 protein bound to human Fab vv304 | VACCINIA VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | vaccinia virus | Zajonc, D.M. | 2.9 | X-RAY DIFFRACTION | 0.297 | 0.247 | false | false | IGHV3 | IGLV3 | Lambda | 0 | -14.728216 | SPR | null | TBD |
4n9o | B | null | 0 | A | protein | null | major prion protein | MEMBRANE PROTEIN/PROTEIN BINDING | 10/21/13 | Probing the N-terminal beta-sheet conversion in the crystal structure of the human prion protein bound to a Nanobody | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Abskharon, R.N.N., Giachin, G., Wohlkonig, A., Soror, S.H., Pardon, E., Legname, G., Steyaert, J. | 1.5 | X-RAY DIFFRACTION | 0.184 | 0.150 | false | true | IGHV3 | null | null | null | null | null | null | null |
7jgj | H | L | 0 | A | protein | null | immunoglobulin a1 protease | IMMUNE SYSTEM | 07/19/20 | IgA1 Protease in complex with neutralizing mAb | STREPTOCOCCUS PNEUMONIAE; MUS MUSCULUS | mus musculus | mus musculus | streptococcus pneumoniae | Eisenmesser, E.Z., Zheng, H. | 4.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6xxn | A | null | 0 | null | null | null | null | ANTITUMOR PROTEIN | 06/10/20 | Crystal structure of NB7, a nanobody targeting prostate specific membrane antigen | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Shahar, A., Rosenfeld, L., Papo, N. | 2.65 | X-RAY DIFFRACTION | 0.231 | 0.182 | false | true | IGHV1 | null | null | null | null | null | null | null |
7s6j | F | G | 0 | E | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 09/14/21 | J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 1) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Ozorowski, G., Torres, J.L., Ward, A.B. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6e5p | H | L | 0 | A | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN | 07/21/18 | Backbone model based on cryo-EM map at 8.5 A of domain-swapped, glycan-reactive, neutralizing antibody 2G12 bound to HIV-1 Env BG505 DS-SOSIP, which was also bound to CD4-binding site antibody VRC03 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Kwong, P.D. | 8.8 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
7m6e | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/ANTIVIRAL PROTEIN | 03/25/21 | Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG10-19 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Barnes, C.O., Bjorkman, P.J. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGLV1 | Lambda | null | null | null | null | null |
7sfw | S | T | 0 | K | protein | null | spike glycoprotein e2 | VIRUS/IMMUNE SYSTEM | 10/04/21 | CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP in complex with Fab hVEEV-63 (focus refine of the asymmetric unit) | VENEZUELAN EQUINE ENCEPHALITIS VIRUS (STRAIN TC-83); HOMO SAPIENS | homo sapiens | homo sapiens | venezuelan equine encephalitis virus (straintc-83) | Binshtein, E., Crowe, J.E. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
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