pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1n8z | B | A | 0 | C | protein | null | receptor protein-tyrosine kinase erbb-2 | TRANSFERASE | 11/21/02 | Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab | HOMO SAPIENS; SYNTHETIC CONSTRUCT | null | homo sapiens | homo sapiens | Cho, H.-S., Mason, K., Ramyar, K.X., Stanley, A.M., Gabelli, S.B., Denney Jr., D.W., Leahy, D.J. | 2.52 | X-RAY DIFFRACTION | 0.284 | 0.222 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1fn4 | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 08/21/00 | CRYSTAL STRUCTURE OF FAB198, AN EFFICIENT PROTECTOR OF ACETYLCHOLINE RECEPTOR AGAINST MYASTHENOGENIC ANTIBODIES | RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | null | Poulas, K., Eliopoulos, E., Vatzaki, E., Navaza, J., Kontou, M. | 2.8 | X-RAY DIFFRACTION | 0.294 | 0.198 | false | false | IGHV2 | IGKV22 | Kappa | null | null | null | null | null |
4jn2 | H | L | 0 | L | Hapten | C24 | 3-({2-[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-3-METHYL-3H-BENZOIMIDAZOLE-5-CARBONYL}-PYRIDIN-2-YL-AMINO)-PROPIONIC ACID ETHYL ESTER | immune system/inhibitor | 03/14/13 | An Antidote for Dabigatran | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Schiele, F., Nar, H. | 1.71 | X-RAY DIFFRACTION | 0.182 | 0.167 | false | true | IGHV4 | IGKV2 | Kappa | 0 | -15.931343 | Unknown | null | TBD |
5w05 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/30/17 | ANTI-TISSUE FACTOR ANTIBODY M59, A HUMANIZED VERSION OF 10H10 | MUS MUSCULUS | mus musculus | mus musculus | null | Teplyakov, A., Obmolova, G., Malia, T.J., Gilliland, G.L. | 1.64 | X-RAY DIFFRACTION | 0.204 | 0.187 | false | true | IGHV5 | IGKV2 | Kappa | null | null | null | null | null |
6umh | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 10/09/19 | Crystal structure of erenumab Fab-a | HOMO SAPIENS | homo sapiens | homo sapiens | null | Mohr, C. | 2.15 | X-RAY DIFFRACTION | 0.224 | 0.185 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
5eul | V | null | 0 | Y | E | protein | protein | NA | NA | protein translocase subunit secy | preprotein translocase sece subunit | PROTEIN TRANSPORT | 11/18/15 | Structure of the SecA-SecY complex with a translocating polypeptide substrate | VICUGNA PACOS; GEOBACILLUS THERMODENITRIFICANS (STRAIN NG80-2); BACILLUS SUBTILIS (STRAIN 168) | vicugna pacos | null | geobacillus thermodenitrificans (strain ng80-2) | geobacillus thermodenitrificans (strain ng80-2) | Li, L., Park, E., Ling, J., Ingram, J., Ploegh, H., Rapoport, T.A. | 3.7 | X-RAY DIFFRACTION | 0.315 | 0.295 | false | true | IGHV1 | null | null | null | null | null | null | null |
5c9k | null | D | 0 | null | null | null | null | IMMUNE SYSTEM | 06/27/15 | Crystal structure of a highly fibrillogenic Arg24Gly mutant of the Recombinant variable domain 6AJL2 | HOMO SAPIENS | null | homo sapiens | null | Hernandez-Santoyo, A., Rodriguez-Romero, A., Luna-Martinez, O.D., Becerril-Lujan, B. | 1.92 | X-RAY DIFFRACTION | 0.219 | 0.170 | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
7zwm | B | C | 0 | A | protein | null | gametocyte surface protein p45/48 | CELL ADHESION | 05/19/22 | Pfs48/45 central and C-terminal domains bound to Fab fragments of monoclonal antibody 10D8 and 32F3 | Mus musculus; Plasmodium falciparum | mus musculus | mus musculus | plasmodium falciparum | Ko, K.T., Lennartz, F.L., Higgins, M.K. | 3.69 | X-RAY DIFFRACTION | 0.280 | 0.255 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
5ihz | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 03/01/16 | Crystal structure of anti-gliadin 1002-1E01 Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Chen, X., Zhao, Y., Harlos, K., Snir, O., Sollid, L.M. | 1.64 | X-RAY DIFFRACTION | 0.229 | 0.200 | false | true | IGHV3 | IGLV4 | Lambda | null | null | null | null | null |
6ffj | A | a | 0 | null | null | null | null | ANTITUMOR PROTEIN | 01/08/18 | Anti-tumor antibody 14F7-derived single chain fragment variable (scFv) | HOMO SAPIENS | homo sapiens | null | null | Bjerregaard-Andersen, K., Heggelund, J.E., Krengel, U. | 2.2 | X-RAY DIFFRACTION | 0.238 | 0.184 | true | true | unknown | unknown | unknown | null | null | null | null | null |
3lmj | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/30/10 | Structure of human anti HIV 21c Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Diskin, R., Marcovecchio, P.M., Bjorkman, P.J. | 2.2 | X-RAY DIFFRACTION | 0.219 | 0.193 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6yxk | A | B | 0 | C | peptide | null | citrullinated vimentin (59-74) | IMMUNE SYSTEM | 05/03/20 | Crystal structure of ACPA 3F3 in complex with cit-vimentin 59-74 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Ge, C., Holmdahl, R. | 2.0 | X-RAY DIFFRACTION | 0.253 | 0.211 | false | true | unknown | IGKV4 | Kappa | null | null | null | null | null |
3wfd | H | L | 0 | B | C | protein | protein | NA | NA | nitric oxide reductase subunit b | nitric oxide reductase subunit c | IMMUNE SYSTEM/OXIDOREDUCTASE | 07/18/13 | Reduced and acetaldoxime-bound cytochrome c-dependent nitric oxide reductase (cNOR) from Pseudomonas aeruginosa in complex with antibody fragment | MUS MUSCULUS; PSEUDOMONAS AERUGINOSA | mus musculus | mus musculus | pseudomonas aeruginosa | pseudomonas aeruginosa | Sato, N., Ishii, S., Hino, T., Sugimoto, H., Fukumori, Y., Shiro, Y., Tosha, T. | 2.3 | X-RAY DIFFRACTION | 0.232 | 0.191 | false | false | IGHV1 | IGKV16 | Kappa | null | null | null | null | null |
6dwi | N | M | 0 | null | null | null | null | IMMUNE SYSTEM | 06/26/18 | Structure of the 4462 Antibody Fab fragment bound to a Staphylococcus aureus wall techoic acid analog | HOMO SAPIENS | homo sapiens | homo sapiens | null | Fong, R., Lupardus, P.J. | 2.39 | X-RAY DIFFRACTION | 0.249 | 0.203 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7ld1 | M | N | 0 | C | protein | null | spike glycoprotein | IMMUNE SYSTEM | 01/12/21 | Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Manne, K., Acharya, P. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
7kfe | G | I | 0 | B | protein | null | spike glycoprotein 1 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/13/20 | Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-329 | HOMO SAPIENS; BUNDIBUGYO EBOLAVIRUS | homo sapiens | homo sapiens | bundibugyo ebolavirus | Murin, C.D., Ward, A.B. | 6.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1rzi | P | O | 0 | null | null | null | null | IMMUNE SYSTEM | 12/24/03 | Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D. | 2.9 | X-RAY DIFFRACTION | 0.321 | 0.233 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3opz | H | L | 0 | A | protein | null | trans-sialidase | hydrolase/immune system | 09/02/10 | Crystal structure of trans-sialidase in complex with the Fab fragment of a neutralizing monoclonal IgG antibody | TRYPANOSOMA CRUZI; MUS MUSCULUS | mus musculus | mus musculus | trypanosoma cruzi | Larrieux, N., Muia, R., Campetella, O., Buschiazzo, A. | 3.4 | X-RAY DIFFRACTION | 0.205 | 0.164 | false | false | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6sc7 | C | null | 0 | A | protein | null | e3 ubiquitin-protein ligase rnf31 | LIGASE | 07/23/19 | dAb3/HOIP-RBR-Ligand3 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | Tsai, Y.-C.I., Johansson, H., House, D., Rittinger, K. | 2.56 | X-RAY DIFFRACTION | 0.267 | 0.224 | false | true | IGHV3 | null | null | null | null | null | null | null |
6oed | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 03/27/19 | CRYSTAL STRUCTURE OF THE RV144 C1-C2 SPECIFIC ANTIBODY CH55 FAB | HOMO SAPIENS | homo sapiens | homo sapiens | null | Yan, F., Van, V., Tolbert, W.D., Pazgier, M. | 2.461 | X-RAY DIFFRACTION | 0.312 | 0.256 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6ous | S | T | 0 | H | G | protein | protein | NA | NA | fusion glycoprotein f1 fused with fibritin trimerizationdomain | fusion glycoprotein f2 | VIRAL PROTEIN/Immune system | 05/05/19 | Structure of fusion glycoprotein from human respiratory syncytial virus | HUMAN RESPIRATORY SYNCYTIAL VIRUS A2; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human respiratory syncytial virus a2, humanimmunodeficiency virus 1 | human respiratory syncytial virus a2 | Su, H.P. | 3.4 | X-RAY DIFFRACTION | 0.275 | 0.245 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5i2i | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 02/08/16 | Structure of cetuximab Fab with cyclic F3Q variant of the meditope | MUS MUSCULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Bzymek, K.P., Williams, J.C. | 2.551 | X-RAY DIFFRACTION | 0.205 | 0.160 | false | true | IGHV2 | IGKV5 | Kappa | null | null | null | null | null |
7rqr | A | B | 0 | C | peptide | null | pfcsp peptide nanpnvdp | IMMUNE SYSTEM | 08/06/21 | Structure of chimeric antibody L9heavy_F10light with PfCSP peptide NANPNVDP | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum 3d7 | Hurlburt, N.K., Pancera, M. | 2.23 | X-RAY DIFFRACTION | 0.238 | 0.189 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5awn | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/06/15 | Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC176 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Lee, J.H., Wilson, I.A., Ward, A.B. | 1.887 | X-RAY DIFFRACTION | 0.223 | 0.177 | false | true | unknown | IGLV2 | Lambda | null | null | null | null | null |
5hhx | H | L | 0 | A | protein | null | interleukin-17a | IMMUNE SYSTEM/INHIBITOR | 01/11/16 | Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Liu, S. | 3.0 | X-RAY DIFFRACTION | 0.263 | 0.176 | false | true | IGHV3 | IGLV6 | Lambda | 0 | -11.201016 | Unknown | null | TBD |
6qd6 | F | null | 0 | null | null | null | null | STRUCTURAL PROTEIN | 12/31/18 | Molecular scaffolds expand the nanobody toolkit for cryo-EM applications: crystal structure of Mb-cHopQ-Nb207 | HELICOBACTER PYLORI; HELICOBACTER PYLORI (STRAIN G27) | helicobacter pylori, helicobacter pylori(strain g27) | null | null | Uchanski, T., Masiulis, S., Fischer, B., Kalichuk, V., Wohlkonig, A., Zogg, T., Remaut, H., Vranken, W., Aricescu, A.R., Pardon, E., Steyaert, J. | 2.84 | X-RAY DIFFRACTION | 0.239 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
7ben | G | I | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 12/24/20 | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-253 and COVOX-75 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Zhao, Y., Ren, J., Stuart, D. | 2.5 | X-RAY DIFFRACTION | 0.282 | 0.240 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3j8d | d | D | 0 | F | protein | null | glycoprotein diii | VIRUS/IMMUNE SYSTEM | 10/13/14 | Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5 | DENGUE VIRUS 2 THAILAND/16681/84; UNIDENTIFIED | null | unidentified | dengue virus 2 thailand/16681/84 | Zhang, X.Z., Sheng, J., Austin, S.K., Hoornweg, T., Smit, J.M., Kuhn, R.J., Diamond, M.S., Rossmann, M.G. | 26 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
2g5b | H | G | 0 | L | peptide | null | bax peptide | APOPTOSIS | 02/22/06 | Crystal Structure of the anti-Bax monoclonal antibody 6A7 and a Bax peptide. | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Peyerl, F.W., Dai, S., Murphy, G.A., Marrack, P., Kappler, J.W. | 2.3 | X-RAY DIFFRACTION | 0.275 | 0.234 | false | true | IGHV7 | IGKV8 | Kappa | null | null | null | null | null |
5w3o | D | E | 0 | B | A | C | protein | protein | protein | NA | NA | NA | viral protein 3 | viral protein 1 | viral protein 2 | VIRUS LIKE PARTICLE/IMMUNE SYSTEM | 06/08/17 | CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, empty particle) | MUS MUSCULUS; HUMAN RHINOVIRUS 14 | mus musculus | mus musculus | human rhinovirus 14 | human rhinovirus 14 | human rhinovirus 14 | Liu, Y., Dong, Y., Rossmann, M.G. | 3.01 | ELECTRON MICROSCOPY | null | null | false | false | IGHV2 | IGKV12 | Kappa | null | null | null | null | null |
6qee | C | B | 0 | A | protein | null | abcb1hm-eq | MEMBRANE PROTEIN | 01/07/19 | Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant in complex with UIC2 Fab and Zosuquidar. | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Alam, A. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7uen | H | L | 0 | A | carbohydrate | GAL | BETA-D-GALACTOSE | IMMUNE SYSTEM | 03/22/22 | Genetic and structural basis of the human anti-alpha-galactosyl antibody response | Mus musculus | mus musculus | mus musculus | null | Langley, D.B., Christ, D. | 1.55 | X-RAY DIFFRACTION | 0.175 | 0.128 | false | true | IGHV6 | IGKV1 | Kappa | null | null | null | null | null |
3qcu | I | M | 0 | I | Hapten | NKN | (2R)-2-HYDROXY-3-(PHOSPHONOOXY)PROPYL TETRADECANOATE | IMMUNE SYSTEM | 01/17/11 | Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (14:0) | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Fleming, J.K., Wojciak, J.M., Campbell, M.-A., Huxford, T. | 1.979 | X-RAY DIFFRACTION | 0.252 | 0.222 | false | true | IGHV5 | IGKV2D | Kappa | null | null | null | null | null |
6iec | C | D | 0 | B | protein | null | nsmgngc | STRUCTURAL PROTEIN/IMMUNE SYSTEM | 04/10/19 | Structure of RVFV Gn and human monoclonal antibody R17 | RIFT VALLEY FEVER VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | rift valley fever virus | Wang, Q.H., Wu, Y., Gao, F., Qi, J.X., Gao, G.F. | 3.2 | X-RAY DIFFRACTION | 0.281 | 0.241 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
7s1m | N | null | 0 | A | B | G | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | MEMBRANE PROTEIN | 09/02/21 | Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 1) | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | homo sapiens | Cary, B.P., Gellman, S.H. | 2.41 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
4uih | D | E | 0 | A | protein | null | dengue virus serotype 2 strain new guinea-c e proteinectodomain | null | 03/30/15 | Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation. | DENGUE VIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | dengue virus 2 | Fibriansah, G., Ibarra, K.D., Ng, T.-S., Smith, S.A., Tan, J.L., Lim, X.N., Ooi, J.S.G., Kostyuchenko, V.A., Wang, J., deSilva, A.M., Harris, E., Crowe, J.E., Lok, S.-M. | 20.0 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7kde | H | L | 0 | G | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/Immune System | 10/08/20 | BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Barnes, C.O., Bjorkman, P.J. | 3.55 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
3aaz | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/28/09 | Crystal structure of the humanized recombinant Fab fragment of a murine; antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Streltsov, V.A. | 2.2 | X-RAY DIFFRACTION | 0.271 | 0.209 | false | true | IGHV2 | IGKV2 | Kappa | null | null | null | null | null |
6x1u | A | B | 0 | C | peptide | null | aclyana-3-ptza peptide | IMMUNE SYSTEM | 05/19/20 | Structure of pHis Fab (SC39-4) in complex with pHis mimetic peptide | ORYCTOLAGUS CUNICULUS; SYNTHETIC CONSTRUCT | oryctolagus cuniculus | oryctolagus cuniculus | synthetic construct | Kalagiri, R., Stanfield, R., Wilson, I.A., Hunter, T. | 1.641 | X-RAY DIFFRACTION | 0.225 | 0.189 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6wha | E | e | 0 | B | C | protein | protein | NA | NA | g subunit q (gi2-mini-gq chimeric) | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN/IMMUNE SYSTEM | 04/07/20 | HTR2A bound to 25-CN-NBOH in complex with a mini-Galpha-q protein, beta/gamma subunits and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM) | ESCHERICHIA COLI; HOMO SAPIENS | homo sapiens | null | homo sapiens | homo sapiens | Skiniotis, G., Roth, B., Kim, K., Panova, O. | 3.36 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7lcv | A | B | 0 | C | protein | null | factor h binding protein | IMMUNE SYSTEM | 01/11/21 | Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein | HOMO SAPIENS; NEISSERIA MENINGITIDIS | homo sapiens | homo sapiens | neisseria meningitidis | Beernink, P.T., Sands, N. | 1.7 | X-RAY DIFFRACTION | 0.270 | 0.240 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
4bjl | null | B | 0 | null | null | null | null | IMMUNOGLOBULIN | 05/26/95 | LOCW, A LAMBDA 1 TYPE LIGHT-CHAIN DIMER (BENCE-JONES PROTEIN) CRYSTALLIZED IN DISTILLED WATER | HOMO SAPIENS | null | homo sapiens | null | Schiffer, M., Huang, D.B. | 2.4 | X-RAY DIFFRACTION | unknown | unknown | false | false | null | IGLV1 | Lambda | null | null | null | null | null |
5c0n | C | D | 0 | B | protein | null | fatty acid-binding protein, adipocyte | LIPID TRANSPORT | 06/12/15 | Development of a monoclonal antibody targeting secreted aP2 to treat diabetes and fatty liver disease | ORYCTOLAGUS CUNICULUS; MUS MUSCULUS | oryctolagus cuniculus | oryctolagus cuniculus | mus musculus | Doyle, C. | 3.0 | X-RAY DIFFRACTION | 0.265 | 0.186 | false | true | IGHV1 | IGKV1 | Kappa | 0.000004 | -7.345158 | SPR | null | TBD |
7lk4 | D | C | 0 | S | protein | null | bcl-2 homologous antagonist/killer | APOPTOSIS | 02/01/21 | Crystal structure of BAK L100A in complex with activating antibody fragments | HOMO SAPIENS; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | homo sapiens | Robin, Y.A., Colman, P.M. | 3.1 | X-RAY DIFFRACTION | 0.262 | 0.214 | false | true | IGHV5 | IGKV16 | Kappa | null | null | null | null | null |
6h6z | D | null | 0 | A | protein | null | capsid protein vp1 | VIRAL PROTEIN | 07/30/18 | GI.1 human norovirus protruding domain in complex with Nano-62 | NORWALK VIRUS (STRAIN GI/HUMAN/UNITED STATES/NORWALK/1968); VICUGNA PACOS | vicugna pacos | null | norwalk virus (strain gi/human/unitedstates/norwalk/1968) | Kilic, T., Hansman, G.S. | 2.085 | X-RAY DIFFRACTION | 0.217 | 0.178 | false | true | IGHV1 | null | null | null | null | null | null | null |
7zr7 | F | G | 0 | C | protein | null | spike glycoprotein,fibritin | STRUCTURAL PROTEIN | 05/03/22 | OMI-42 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; TEQUATROVIRUS T4; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2, tequatrovirus t4 | Duyvesteyn, H.M.E., Ren, J., Stuart, D.I. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
1g7h | B | A | 0 | C | protein | null | lysozyme c | HYDROLASE INHIBITOR/HYDROLASE | 11/10/00 | CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3(VLW92A) | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | gallus gallus | Sundberg, E.J., Urrutia, M., Braden, B.C., Isern, J., Mariuzza, R.A. | 1.85 | X-RAY DIFFRACTION | unknown | 0.203 | false | true | IGHV2 | IGKV12 | Kappa | null | null | null | null | null |
43ca | D | C | 0 | C | Hapten | NPO | P-NITROPHENOL | IMMUNOGLOBULIN | 03/10/99 | CRYSTALLOGRAPHIC STRUCTURE OF THE ESTEROLYTIC AND AMIDOLYTIC 43C9 ANTIBODY WITH BOUND P-NITROPHENOL | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Thayer, M.M., Getzoff, E.D., Roberts, V.A. | 2.3 | X-RAY DIFFRACTION | 0.259 | 0.206 | false | true | IGHV2 | IGKV8 | Kappa | null | null | null | null | null |
7jlk | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 07/29/20 | Crystal structure of glVRC01 Fab in complex with anti-idiotype iv1 scFv | MUS MUSCULUS; HOMO SAPIENS | homo sapiens | homo sapiens | null | Weidle, C., Pancera, M. | 1.99 | X-RAY DIFFRACTION | 0.235 | 0.179 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4krp | B | null | 0 | A | protein | null | epidermal growth factor receptor | TRANSFERASE/IMMUNE SYSTEM | 05/16/13 | Nanobody/VHH domain 9G8 in complex with the extracellular region of EGFR | HOMO SAPIENS; LAMA GLAMA; MUS MUSCULUS, HOMO SAPIENS | lama glama | null | homo sapiens | Ferguson, K.M., Schmitz, K.R. | 2.823 | X-RAY DIFFRACTION | 0.263 | 0.215 | false | true | IGHV1 | null | null | 0 | -9.249427 | SPR | null | TBD |
6sc5 | C | null | 0 | A | protein | null | e3 ubiquitin-protein ligase rnf31 | LIGASE | 07/23/19 | dAb3/HOIP-RBR-Ligand2 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | Tsai, Y.-C.I., Johansson, H., House, D., Rittinger, K. | 2.1 | X-RAY DIFFRACTION | 0.252 | 0.219 | false | true | IGHV3 | null | null | null | null | null | null | null |
7wwl | H | L | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 02/13/22 | S protein of Delta variant in complex with ZWD12 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Guo, Y.Y., Zhang, Y.Y., Zhou, Q. | 3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
1r3l | B | A | 0 | C | protein | null | voltage-gated potassium channel | MEMBRANE PROTEIN | 10/02/03 | potassium channel KcsA-Fab complex in Cs+ | STREPTOMYCES LIVIDANS; MUS MUSCULUS | mus musculus | mus musculus | streptomyces lividans | Zhou, Y., MacKinnon, R. | 2.41 | X-RAY DIFFRACTION | 0.249 | 0.219 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
2xqb | H | L | 0 | A | protein | null | interleukin 15 | IMMUNE SYSTEM | 09/01/10 | Crystal Structure of anti-IL-15 Antibody in Complex with human IL-15 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Lowe, D.C., Gerhardt, S., Ward, A., Hargreaves, D., Anderson, M., StGallay, S., Vousden, K., Ferraro, F., Pauptit, R.A., Cochrane, D., Pattison, D.V., Buchanan, C., Popovic, B., Finch, D.K., Wilkinson, T., Sleeman, M., Vaughan, T.J., Cruwys, S., Mallinder, P.R. | 2.6 | X-RAY DIFFRACTION | 0.31811 | 0.24441 | false | true | IGHV1 | IGLV1 | Lambda | 0 | -14.02 | SPR | null | 21167836 |
7rth | L | K | 0 | null | null | null | null | IMMUNE SYSTEM | 08/13/21 | Crystal structure of an anti-lysozyme nanobody in complex with an anti-nanobody Fab ""NabFab"" | HOMO SAPIENS | homo sapiens | homo sapiens | null | Filippova, E.V., Mukherjee, S., Bloch, J.S., Locher, K.P., Kossiakoff, A.A. | 3.19 | X-RAY DIFFRACTION | 0.267 | 0.216 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6ao0 | null | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/15/17 | CAT192 Fab Insertion Mutant H2/L2 | HOMO SAPIENS | null | homo sapiens | null | Lord, D.M., Wei, R.R. | 2.35 | X-RAY DIFFRACTION | 0.261 | 0.206 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
5toj | D | null | 0 | A | protein | null | fusion glycoprotein f0, fibritin chimera | VIRAL PROTEIN/IMMUNE SYSTEM | 10/17/16 | Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4 | HUMAN RESPIRATORY SYNCYTIAL VIRUS; LAMA GLAMA | lama glama | null | human respiratory syncytial virus | Gilman, M.S.A., Kabeche, S.C., McLellan, J.S. | 3.3 | X-RAY DIFFRACTION | 0.234 | 0.184 | false | true | IGHV1 | null | null | 0 | -10.420468 | SPR | null | TBD |
6udj | N | O | 0 | G | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 09/19/19 | HIV-1 bNAb 1-18 in complex with BG505 SOSIP.664 and 10-1074 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Abernathy, M.E., Barnes, C.O., Gristick, H.B., Bjorkman, P.J. | 2.5 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
4hem | F | null | 0 | C | protein | null | bpp | VIRAL PROTEIN | 10/04/12 | Llama vHH-02 binder of ORF49 (RBP) from lactococcal phage TP901-1 | LACTOCOCCUS PHAGE TP901-1; LAMA GLAMA | lama glama | null | lactococcus phage tp901-1 | Desmyter, A., Spinelli, S., Farenc, C., Blangy, S., Bebeacua, C., van Sinderen, D., Mahony, J., Cambillau, C. | 1.65 | X-RAY DIFFRACTION | 0.177 | 0.167 | false | true | IGHV1 | null | null | null | null | null | null | null |
6k4z | B | b | 0 | b | Hapten | NPA | 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID | IMMUNE SYSTEM | 05/27/19 | Single-chain Fv antibody of C6 COMPLEXED WITH 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID | MUS MUSCULUS | mus musculus | null | null | Nishiguchi, A., Numoto, N., Ito, N., Azuma, T., Oda, M. | 1.65 | X-RAY DIFFRACTION | 0.196 | 0.167 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6cnw | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 03/09/18 | STRUCTURE OF HUMANIZED SINGLE DOMAIN ANTIBODY SD84 | HYBRID | hybrid | null | null | Luo, J., Obmolova, O. | 0.92 | X-RAY DIFFRACTION | 0.139 | 0.126 | false | true | IGHV3 | null | null | null | null | null | null | null |
5wdu | D | E | 0 | G | protein | null | envelope glycoprotein gp160 | IMMUNE SYSTEM | 07/06/17 | HIV-1 Env BG505 SOSIP.664 H72C-H564C trimer in complex with bNAbs PGT122 Fab, 35O22 Fab and NIH45-46 scFv | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Julien, J.-P., Torrents de la Pena, A., Sanders, R.W., Wilson, I.A. | 7.0 | X-RAY DIFFRACTION | 0.363 | 0.301 | false | true | unknown | unknown | unknown | null | null | null | null | null |
6foe | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/07/18 | BaxB01 Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Hollerweger, J., Schinagl, A., Kerschbaumer, R.J., Scheiflinger, F., Thiele, M., Goettig, P., Brandstetter, H. | 2.6 | X-RAY DIFFRACTION | 0.263 | 0.214 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7zr8 | H | L | 0 | A | protein | null | spike glycoprotein,fibritin | STRUCTURAL PROTEIN | 05/03/22 | OMI-38 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE RBD (local refinement) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; ENTEROBACTERIA PHAGE T4; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2, enterobacteria phage t4 | Duyvesteyn, H.M.E., Ren, J., Stuart, D.I. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3g6a | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 02/06/09 | Crystal structure of anti-IL-13 antibody CNTO607 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Teplyakov, A., Obmolova, G., Gilliland, G.L. | 2.1 | X-RAY DIFFRACTION | 0.283 | 0.208 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
7lf2 | F | H | 0 | B | protein | null | arginase-1 | HYDROLASE/IMMUNE SYSTEM | 01/15/21 | Trimeric human Arginase 1 in complex with mAb4 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gomez-Llorente, Y., Scapin, G., Palte, R.L. | 3.72 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4nkd | A | B | 0 | null | null | null | null | IMMUNE SYSTEM/CHAPERONE | 11/12/13 | Crystal structure of engineered anti-EE scFv antibody fragment | MUS MUSCULUS | mus musculus | mus musculus | null | Kalyoncu, S., Hyun, J., Pai, J.C., Johnson, J.L., Etzminger, K., Jain, A., Heaner Jr., D., Molares, I.A., Truskett, T.M., Maynard, J.A., Lieberman, R.L. | 3.303 | X-RAY DIFFRACTION | 0.231 | 0.195 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3ab0 | B | C | 0 | A | protein | null | bcla protein | IMMUNE SYSTEM | 11/28/09 | Crystal structure of complex of the Bacillus anthracis major spore surface protein BclA with ScFv antibody fragment | BACILLUS ANTHRACIS; MUS MUSCULUS | mus musculus | mus musculus | bacillus anthracis | Streltsov, V.A. | 3.09 | X-RAY DIFFRACTION | 0.265 | 0.197 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7rd5 | B | A | 0 | F | protein | null | tetraspanin-15 | CELL ADHESION | 07/09/21 | Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) in complex with 1C12 Fab | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Lipper, C.H., Gabriel, K.H., Seegar, T.C.M., Durr, K.L., Tomlinson, M.G., Blacklow, S.C. | 3.6 | X-RAY DIFFRACTION | 0.309 | 0.271 | false | true | IGHV1 | IGKV15 | Kappa | null | null | null | null | null |
4k3h | null | C | 0 | D | Hapten | 1OM | 4-{bis[4-(dimethylamino)phenyl]methyl}phenol | immune system/inhibitor | 04/10/13 | Immunoglobulin lambda variable domain L5(L89S) fluorogen activationg protein in complex with malachite green | HOMO SAPIENS | null | homo sapiens | homo sapiens | Stanfield, R.L., Szent-Gyorgyi, C., Wilson, I.A. | 2.45 | X-RAY DIFFRACTION | 0.225 | 0.194 | false | true | null | IGLV7 | Lambda | 0 | -9.350354 | Unknown | null | TBD |
5wt9 | H | L | 0 | G | protein | null | programmed cell death protein 1 | IMMUNE SYSTEM | 12/10/16 | Complex structure of PD-1 and nivolumab-Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Tan, S., Zhang, H., Chai, Y., Song, H., Tong, Z., Wang, Q., Qi, J., Wong, G., Zhu, X., Liu, W.J., Gao, S., Wang, Z., Shi, Y., Yang, F., Gao, G.F., Yan, J. | 2.401 | X-RAY DIFFRACTION | 0.228 | 0.187 | false | true | IGHV3 | IGKV3 | Kappa | 0 | -12.058051 | SPR | null | TBD |
5ja8 | D | null | 0 | C | protein | null | toxin higb-2 | TOXIN | 04/12/16 | Crystal structure of the HigB2 toxin in complex with Nb2 | LAMA GLAMA; VIBRIO CHOLERAE SEROTYPE O1 (STRAIN ATCC 39315 / EL TOR INABA N16961) | lama glama | null | vibrio cholerae serotype o1 (strain atcc 39315/ el tor inaba n16961) | Hadzi, S., Loris, R. | 2.49 | X-RAY DIFFRACTION | 0.248 | 0.201 | false | true | IGHV1 | null | null | null | null | null | null | null |
7q0h | H | L | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN | 10/14/21 | Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-50 and Beta-54 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 3.65 | X-RAY DIFFRACTION | 0.303 | 0.255 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6ayn | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 09/08/17 | Structure of cetuximab with aminoheptanoic acid-linked N-(3-aminopropyl)-L-arginine meditope variant | MUS MUSCULUS; HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Bzymek, K.P., Williams, J.C. | 2.48 | X-RAY DIFFRACTION | 0.222 | 0.172 | false | true | IGHV2 | IGKV5 | Kappa | 0.000009 | -6.870623 | Unknown | null | TBD |
4nhg | M | K | 0 | null | null | null | null | IMMUNE SYSTEM | 11/05/13 | Crystal Structure of 2G12 IgG Dimer | HOMO SAPIENS | homo sapiens | homo sapiens | null | Wu, Y., West, Jr., A.P., Kim, H.J., Thornton, M.E., Ward, A.B., Bjorkman, P.J. | 8.001 | X-RAY DIFFRACTION | 0.369 | 0.359 | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
3whe | S | T | 0 | D | protein | null | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 08/25/13 | A new conserved neutralizing epitope at the globular head of hemagglutinin in H3N2 influenza viruses | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Fujii, Y., Sumida, T., Shirouzu, M., Yokoyama, S. | 4.0 | X-RAY DIFFRACTION | 0.308 | 0.235 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7z1a | E | null | 0 | C | protein | null | spike protein s1 | ANTIVIRAL PROTEIN | 02/24/22 | Nanobody H11 and F2 bound to RBD | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Mikolajek, H., Naismith, J.H. | 2.59 | X-RAY DIFFRACTION | 0.241 | 0.208 | false | true | IGHV1 | null | null | null | null | null | null | null |
4nco | D | C | 0 | A | protein | null | bg505 sosip gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/24/13 | Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Julien, J.-P., Stanfield, R.L., Lyumkis, D., Ward, A.B., Wilson, I.A. | 4.7 | X-RAY DIFFRACTION | 0.389 | 0.375 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
5mv3 | F | G | 0 | H | peptide | null | synthetic peptide containing the cii583-591 epitope ofcollagen type ii,collagen alpha-1(ii) chain,synthetic peptide containing the cii583-591 epitope of collagen type ii, | IMMUNE SYSTEM | 01/15/17 | ACC1 Fab fragment in complex with CII583-591 (CG10) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | mus musculus | Dobritzsch, D., Holmdahl, R., Ge, C. | 2.95 | X-RAY DIFFRACTION | 0.261 | 0.202 | false | false | IGHV6 | IGKV3 | Kappa | null | null | null | null | null |
4ydl | B | C | 0 | A | protein | null | envelope glycoprotein gp160,envelope glycoprotein gp160 | IMMUNE SYSTEM | 02/22/15 | Crystal structure of broadly and potently neutralizing antibody C38-VRC18.02 in complex with HIV-1 clade AE strain 93TH057gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Srivatsan, S., Kwong, P.D. | 1.8 | X-RAY DIFFRACTION | 0.207 | 0.174 | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
3nz8 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/16/10 | Crystal structure of the HIV-2 neutralizing Fab fragment 7C8 | MUS MUSCULUS | mus musculus | mus musculus | null | Uchtenhagen, H, Friemann, R, Raszewski, G, Spetz, A-L, Nilsson, L, Achour, A | 2.7 | X-RAY DIFFRACTION | 0.273 | 0.226 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3fku | T | t | 0 | L | K | protein | protein | NA | NA | hemagglutinin | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 12/17/08 | Crystal structure of influenza hemagglutinin (H5) in complex with a broadly neutralizing antibody F10 | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | null | influenza a virus | influenza a virus | Hwang, W.C., Santelli, E., Stec, B., Wei, G., Cadwell, G., Bankston, L.A., Sui, J., Perez, S., Aird, D., Chen, L.M., Ali, M., Murakami, A., Yammanuru, A., Han, T., Cox, N., Donis, R.O., Liddington, R.C., Marasco, W.A. | 3.2 | X-RAY DIFFRACTION | 0.286 | 0.232 | true | true | unknown | unknown | unknown | 0 | -13.48 | SPR | 25 | 19234466 |
5ja8 | B | null | 0 | A | protein | null | toxin higb-2 | TOXIN | 04/12/16 | Crystal structure of the HigB2 toxin in complex with Nb2 | LAMA GLAMA; VIBRIO CHOLERAE SEROTYPE O1 (STRAIN ATCC 39315 / EL TOR INABA N16961) | lama glama | null | vibrio cholerae serotype o1 (strain atcc 39315/ el tor inaba n16961) | Hadzi, S., Loris, R. | 2.49 | X-RAY DIFFRACTION | 0.248 | 0.201 | false | true | IGHV1 | null | null | null | null | null | null | null |
7ly2 | F | C | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 03/05/21 | SARS-CoV-2 S/S2M11/S2M28 Global Refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 2.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6ii9 | P | Q | 0 | E | protein | null | hemagglutinin | IMMUNE SYSTEM | 10/03/18 | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L3A-44 | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Jiang, H.H., Shi, Y., Qi, J., Gao, G.F. | 3.5 | X-RAY DIFFRACTION | 0.234 | 0.201 | false | true | IGHV4 | IGLV1 | Lambda | 0 | -10.521321 | SPR | null | TBD |
7dhr | N | null | 0 | A | B | G | protein | protein | peptide | NA | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | SIGNALING PROTEIN | 11/17/20 | Cryo-EM structure of the full agonist isoprenaline-bound beta2 adrenergic receptor-Gs protein complex. | HOMO SAPIENS; BOS TAURUS; LAMA GLAMA | lama glama | null | homo sapiens | bos taurus | bos taurus | Yang, F., Ling, S.L., Zhou, Y.X., Zhang, Y.N., Lv, P., Liu, S.L., Fang, W., Sun, W.J., Hu, L.Y.A. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7b27 | C | null | 0 | A | protein | null | unknown | VIRAL PROTEIN | 11/26/20 | RBD domain SARS-CoV2 in complex with neutralizing nanobody NM1230 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; VICUGNA PACOS | null | null | null | Ostertag, E., Zocher, G., Stehle, T. | 2.902 | X-RAY DIFFRACTION | 0.305 | 0.266 | false | false | unknown | unknown | unknown | null | null | null | null | null |
7bh8 | E | F | 0 | C | Q | protein | peptide | NA | NA | hla class i histocompatibility antigen, alpha chain e | vl9 leader peptide | IMMUNE SYSTEM | 01/10/21 | 3H4-Fab HLA-E-VL9 co-complex | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | homo sapiens | Walters, L.C., Rozbesky, D. | 1.8 | X-RAY DIFFRACTION | 0.232 | 0.195 | false | true | IGHV1 | IGKV14 | Kappa | null | null | null | null | null |
7mtb | H | L | 2 | G | protein | null | rhodopsin kinase grk1 | MEMBRANE, Signaling protein/Immune System | 05/13/21 | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6 | BOS TAURUS; HOMO SAPIENS | homo sapiens | homo sapiens | bos taurus | Chen, Q., Chen, C.-L., Tesmer, J.J.G. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6n5d | C | D | 0 | A | protein | null | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 11/21/18 | Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope | INFLUENZA A VIRUS; MUS MUSCULUS | mus musculus | mus musculus | influenza a virus | Bajic, G., Schmidt, A.G. | 3.0 | X-RAY DIFFRACTION | 0.244 | 0.217 | false | true | IGHV5 | IGLV1 | Lambda | null | null | null | null | null |
4dqo | H | L | 0 | C | protein | null | 1fd6-v1v2 scaffold zm109 hiv-1 strain | IMMUNE SYSTEM | 02/16/12 | Crystal Structure of PG16 Fab in Complex with V1V2 Region from HIV-1 strain ZM109 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Pancera, M., McLellan, J.S., Kwong, P.D. | 2.438 | X-RAY DIFFRACTION | 0.230 | 0.201 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
5wcc | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 06/29/17 | Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 02-1F07 Fab. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Joyce, M.G., Andrews, S.F., Mascola, J.R., McDermott, A.B., Kwong, P.D. | 2.461 | X-RAY DIFFRACTION | 0.240 | 0.203 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
7ld1 | P | O | 0 | A | protein | null | spike glycoprotein | IMMUNE SYSTEM | 01/12/21 | Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Manne, K., Acharya, P. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6i04 | H | L | 0 | A | protein | null | hepatocyte growth factor receptor | IMMUNE SYSTEM | 10/25/18 | Crystal structure of Sema domain of the Met receptor in complex with FAB | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Casaletto, J.B., Geddie, M.L., Abu-Yousif, A.O., Masson, K., Fulgham, A., Boudot, A., Maiwald, T., Kearns, J.D., Kohli, N., Su, S., Razlog, M., Raue, A., Kalra, A., Hakansson, M., Logan, D.T., Welin, M., Chattopadhyay, S., Harms, B.D., Nielsen, U.B., Schoeberl, B., Lugovskoy, A.A., MacBeath, G. | 3.1 | X-RAY DIFFRACTION | 0.261 | 0.202 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
2bx5 | null | C | 0 | null | null | null | null | ANTIBODY | 07/22/05 | Is FR1 the antibody's Achillies heel | ESCHERICHIA COLI | null | null | null | James, L.C. | 2.7 | X-RAY DIFFRACTION | 0.290 | 0.250 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
4wfh | G | F | 0 | B | protein | null | potassium channel subfamily k member 4 | METAL TRANSPORT | 09/15/14 | Human TRAAK K+ channel in a Tl+ bound nonconductive conformation | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Brohawn, S.G., MacKinnon, R. | 3.01 | X-RAY DIFFRACTION | 0.239 | 0.203 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
7lg6 | K | N | 0 | F | G | protein | protein | NA | NA | envelope glycoprotein gp120 | envelope glycoprotein gp41 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/19/21 | BG505 SOSIP.v5.2 in complex with VRC40.01 and RM19R Fabs | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Cottrell, C.A., Torres, J.L., Wu, N.R., Ward, A.B. | 3.28 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
4at6 | J | K | 0 | null | null | null | null | IMMUNE SYSTEM | 05/04/12 | Fab fragment of antiporphyrin antibody 14H7 | MUS MUSCULUS | mus musculus | mus musculus | null | Golinelli-Pimpaneau, B., Mahy, J.P. | 2.549 | X-RAY DIFFRACTION | 0.3281 | 0.2791 | false | false | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6nfu | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | membrane protein, metal transport | 12/20/18 | Structure of the KcsA-G77A mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter. | MUS MUSCULUS; STREPTOMYCES LIVIDANS | mus musculus | mus musculus | streptomyces lividans | Tilegenova, C., Cortes, D.M., Jahovic, N., Hardy, E., Parameswaran, H., Guan, L., Cuello, L.G. | 2.09 | X-RAY DIFFRACTION | 0.224 | 0.210 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
7s8n | E | e | 0 | B | C | protein | protein | NA | NA | gs-mini-gq chimera | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 09/18/21 | CryoEM structure of Gq-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | homo sapiens | Cao, C., Fay, J.F., Gumpper, R.H., Roth, B.L. | 2.9 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
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