pdb
stringlengths
4
4
Hchain
stringclasses
59 values
Lchain
stringclasses
60 values
model
int64
0
76
antigen_chain
stringclasses
386 values
antigen_type
stringclasses
24 values
antigen_het_name
stringclasses
240 values
antigen_name
stringlengths
1
396
short_header
stringclasses
448 values
date
stringlengths
8
8
compound
stringlengths
4
243
organism
stringlengths
3
175
heavy_species
stringclasses
121 values
light_species
stringclasses
67 values
antigen_species
stringclasses
937 values
authors
stringlengths
6
762
resolution
stringlengths
1
8
method
stringclasses
10 values
r_free
stringclasses
354 values
r_factor
stringclasses
342 values
scfv
bool
2 classes
engineered
bool
2 classes
heavy_subclass
stringclasses
14 values
light_subclass
stringclasses
35 values
light_ctype
stringclasses
3 values
affinity
float64
0
0
delta_g
float64
-16.91
-5.04
affinity_method
stringclasses
11 values
temperature
float64
4
37
pmid
stringclasses
157 values
7t3d
K
N
0
F
protein
null
hemagglutinin ha1 chain
Viral Protein/IMMUNE SYSTEM
12/07/21
CryoEM map of anchor 222-1C06 Fab and lateral patch 2B05 Fab binding H1 HA
INFLUENZA A VIRUS (A/CALIFORNIA/04/2009(H1N1)); HOMO SAPIENS
homo sapiens
homo sapiens
influenza a virus (a/california/04/2009(h1n1))
Han, J., Ward, A.B.
3.2
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
2wuc
H
L
0
A
protein
null
hepatocyte growth factor activator long chain
HYDROLASE/HYDROLASE INHIBITOR
10/01/09
Crystal structure of HGFA in complex with the allosteric non- inhibitory antibody Fab40.deltaTrp and Ac-KQLR-chloromethylketone
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
homo sapiens
Ganesan, R., Eigenbrot, C., Shia, S., ,
2.7
X-RAY DIFFRACTION
0.274
0.226
false
true
IGHV3
IGKV1
Kappa
0
-9.26
SPR
25
20004165
6gci
B
null
0
A
protein
null
mitochondrial adp/atp carrier
MEMBRANE PROTEIN
04/17/18
Structure of the bongkrekic acid-inhibited mitochondrial ADP/ATP carrier
THERMOTHELOMYCES THERMOPHILA (STRAIN ATCC 42464 / BCRC 31852 / DSM 1799); LAMA GLAMA
lama glama
null
thermothelomyces thermophila (strain atcc 42464/ bcrc 31852 / dsm 1799)
Ruprecht, J.J., King, M.S., Pardon, E., Aleksandrova, A.A., Zogg, T., Crichton, P.G., Steyaert, J., Kunji, E.R.S.
3.3
X-RAY DIFFRACTION
0.283
0.252
false
true
IGHV1
null
null
null
null
null
null
null
4mxv
H
L
0
A
protein
null
lymphotoxin-alpha
CYTOKINE/IMMUNE SYSTEM
09/26/13
Structure of Lymphotoxin alpha bound to anti-LTa Fab
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Yin, J.P., Hymowitz, S.G.
3.2
X-RAY DIFFRACTION
0.235
0.177
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
2p8m
B
A
0
C
peptide
null
gp41 peptide
viral protein
03/22/07
Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELLELDKWASLWN in new crystal form
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
null
Julien, J.P., Bryson, S., Pai, E.F.
2.7
X-RAY DIFFRACTION
0.238
0.223
false
false
IGHV2
IGKV1
Kappa
null
null
null
null
null
7e5r
I
K
0
C
protein
null
spike glycoprotein
VIRAL PROTEIN/IMMUNE SYSTEM
02/20/21
SARS-CoV-2 S trimer with three-antibody cocktail complex
HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Sun, Y., Wang, L., Wang, N., Feng, R., Wang, X.
3.6
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
2aeq
H
L
0
A
protein
null
neuraminidase
HYDROLASE/IMMUNE SYSTEM
07/23/05
An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex.
INFLUENZA A VIRUS; MUS MUSCULUS
mus musculus
mus musculus
influenza a virus
Venkatramani, L., Bochkarev, A., Air, G.M.
3.0
X-RAY DIFFRACTION
0.312
0.267
false
false
IGHV7
IGKV6
Kappa
0
-10.8
Other
null
16384583
3fo1
B
A
0
B
Hapten
BZH
5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID
IMMUNE SYSTEM
12/27/08
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Ala mutant)
MUS MUSCULUS, HOMO SAPIENS
mus musculus, homo sapiens
mus musculus, homo sapiens
mus musculus, homo sapiens
Debler, E.W., Wilson, I.A.
2.2
X-RAY DIFFRACTION
0.281
0.225
false
true
IGHV2
IGKV1
Kappa
null
null
null
null
null
6bzv
E
F
0
K
peptide
null
e2 as412 peptide
IMMUNE SYSTEM
12/26/17
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the GL precursor of the broadly neutralizing antibody 19B3
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
hepatitis c virus
Tzarum, N., Alemn, F., Wilson, I.A., Law, M.
2.654
X-RAY DIFFRACTION
0.241
0.199
false
true
IGHV3
IGKV3
Kappa
null
null
null
null
null
6mam
C
D
0
L | K
protein | protein
NA | NA
envelope glycoprotein | envelope glycoprotein
Viral protein/immune system
08/28/18
Cleaved Ebola GP in complex with a broadly neutralizing human antibody, ADI-15946
HOMO SAPIENS; ZAIRE EBOLAVIRUS (STRAIN MAYINGA-76)
homo sapiens
homo sapiens
zaire ebolavirus (strain mayinga-76) | zaire ebolavirus (strain mayinga-76)
West, B.R., Moyer, C.L., Fusco, M.L., Saphire, E.O.
4.1
X-RAY DIFFRACTION
0.281
0.262
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
7cwo
H
L
0
A
protein
null
spike glycoprotein
VIRAL PROTEIN
08/29/20
SARS-CoV-2 spike protein RBD and P17 fab complex
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Wang, X., Wang, N.
3.9
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
6pz8
H
L
0
B
protein
null
s protein
VIRAL PROTEIN/IMMUNE SYSTEM
07/31/19
MERS S0 trimer in complex with variable domain of antibody G2
MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS; MUS MUSCULUS
mus musculus
mus musculus
middle east respiratory syndrome-relatedcoronavirus
Bowman, C.A., Pallesen, J., Ward, A.B.
4.19
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
3iu3
C
D
0
J
protein
null
interleukin-2 receptor alpha chain
IMMUNE SYSTEM
08/29/09
Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain
HOMO SAPIENS; SYNTHETIC CONSTRUCT
null
null
homo sapiens
Du, J., Yang, H., Wang, J., Ding, J.
2.9
X-RAY DIFFRACTION
0.262
0.215
false
true
IGHV1
IGKV4
Kappa
0
-13.44
SPR
25
20032294
4dka
B
null
0
null
null
null
null
RNA BINDING PROTEIN/IMMUNE SYSTEM
02/03/12
Structure of Editosome protein
LAMA GLAMA; TRYPANOSOMA BRUCEI
lama
null
null
Park, Y.-J., Hol, W.
1.97
X-RAY DIFFRACTION
0.229
0.187
false
true
IGHV1
null
null
null
null
null
null
null
6o9h
H
L
0
D
protein
null
ecd
IMMUNE SYSTEM
03/13/19
Mouse ECD with Fab1
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Min, X., Wang, Z.
2.1
X-RAY DIFFRACTION
0.248
0.203
false
true
IGHV5
IGKV8
Kappa
null
null
null
null
null
6xsn
H
L
0
C
peptide
null
16055_v1v2-1fd6
IMMUNE SYSTEM
07/15/20
Crystal structure of NHP VD20.5A4 Fab in complex with 16055 V1V2 1FD6 scaffold
MACACA MULATTA
macaca mulatta
macaca mulatta
macaca mulatta
Aljedani, S., Pancera, M.
2.87
X-RAY DIFFRACTION
0.267
0.221
false
false
IGHV4
IGKV1
Kappa
null
null
null
null
null
5gs1
F
f
0
null
null
null
null
IMMUNE SYSTEM
08/13/16
Crystal structure of homo-specific diabody
HOMO SAPIENS
homo sapiens
null
null
Kim, J.H., Song, D.H., Youn, S.J., Kim, J.W., Cho, G., Lee, H., Lee, J.O.
2.0
X-RAY DIFFRACTION
0.286
0.267
true
true
unknown
unknown
unknown
null
null
null
null
null
5icy
B
A
0
null
null
null
null
IMMUNE SYSTEM
02/23/16
Cetuximab Fab in complex with linear meditope
MUS MUSCULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT
mus musculus, homo sapiens
mus musculus, homo sapiens
null
Bzymek, K.P., Williams, J.C.
2.5
X-RAY DIFFRACTION
0.206
0.160
false
true
IGHV2
IGKV5
Kappa
0.000009
-6.903731
Unknown
null
TBD
5dhv
A
B
0
N
protein
null
protein rev
IMMUNE SYSTEM
08/31/15
HIV-1 Rev NTD dimers with variable crossing angles
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1
DiMattia, M.A., Watts, N.R., Wingfield, P.T., Grimes, J.M., Stuart, D.I., Steven, A.C.
2.3
X-RAY DIFFRACTION
0.227
0.188
false
true
IGHV1
IGKV1
Kappa
null
null
null
null
null
7oap
F
null
0
E
protein
null
unknown
ANTIVIRAL PROTEIN
04/19/21
Nanobody H3 AND C1 bound to RBD
LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2
null
null
null
Naismith, J.H., Mikolajek, H.
1.901
X-RAY DIFFRACTION
0.204
0.180
false
false
IGHV1
null
null
null
null
null
null
null
1moe
A
a
0
null
null
null
null
IMMUNE SYSTEM
09/09/02
The three-dimensional structure of an engineered scFv T84.66 dimer or diabody in VL to VH linkage.
MUS MUSCULUS
mus musculus
null
null
Carmichael, J.A., Power, B.E., Garrett, T.P.J., Yazaki, P.J., Shively, J.E., Raubischek, A.A., Wu, A.M., Hudson, P.J.
2.6
X-RAY DIFFRACTION
0.300
0.213
true
true
unknown
unknown
unknown
null
null
null
null
null
1sjv
A
null
0
null
null
null
null
ANTIBIOTIC
03/04/04
Three-Dimensional Structure of a Llama VHH Domain Swapping
LAMA GLAMA
lama glama
null
null
Spinelli, S., Desmyter, A., Frenken, L., Verrips, T., Cambillau, C.
1.94
X-RAY DIFFRACTION
0.225
0.206
false
true
IGHV1
null
null
null
null
null
null
null
5th9
J
N
0
C
protein
null
matrix metalloproteinase-9,matrix metalloproteinase-9
hydrolase/hydrolase inhibitor
09/29/16
Structure determination of a potent, selective antibody inhibitor of human MMP9 (GS-5745 bound to MMP-9)
ORYCTOLAGUS CUNICULUS; HOMO SAPIENS
oryctolagus cuniculus
oryctolagus cuniculus
homo sapiens
Appleby, T.C., Greenstein, A.E., Kwon, H.J.
2.999
X-RAY DIFFRACTION
0.257
0.218
false
true
IGHV2
IGKV6
Kappa
null
null
null
null
null
7rdw
Q
R
0
C
protein
null
glycoprotein 120
IMMUNE SYSTEM
07/12/21
Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1
Weidle, C., Pancera, M.
3.55
X-RAY DIFFRACTION
0.295
0.260
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
6mb3
J
S
0
E
protein
null
plasmodium falciparum recombinant shortened csp
IMMUNE SYSTEM
08/29/18
Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
PLASMODIUM FALCIPARUM; HOMO SAPIENS
homo sapiens
homo sapiens
plasmodium falciparum
Cottrell, C.A., Torres, J.L., Ward, A.B.
3.37
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGLV1
Lambda
null
null
null
null
null
7q9p
J
K
0
C
protein
null
spike glycoprotein
VIRAL PROTEIN
11/12/21
Beta-06 fab in complex with SARS-CoV-2 beta-Spike glycoprotein
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Duyvesteyn, H.M.E., Ren, J., Stuart, D.I.
4.5
ELECTRON MICROSCOPY
null
null
false
true
IGHV4
IGKV3
Kappa
null
null
null
null
null
4xbg
C
D
0
null
null
null
null
IMMUNE SYSTEM
12/16/14
Crystal structure of human 4E10 Fab in complex with phosphatidic acid (06:0 PA): 2.73 A resolution
HOMO SAPIENS
homo sapiens
homo sapiens
null
Irimia, A., Stanfield, R.L., Wilson, I.A.
2.73
X-RAY DIFFRACTION
0.246
0.202
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
3j70
A
B
0
D
protein
null
envelope glycoprotein gp120
VIRAL PROTEIN/IMMUNE SYSTEM
04/22/14
Model of gp120, including variable regions, in complex with CD4 and 17b
HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1
homo sapiens
homo sapiens
human immunodeficiency virus 1
Rasheed, M., Bettadapura, R., Bajaj, C.
NOT
ELECTRON MICROSCOPY
null
null
false
false
IGHV1
IGKV1
Kappa
null
null
null
null
null
6ad8
E
F
0
B
protein
null
h(+)/cl(-) exchange transporter clca
TRANSPORT PROTEIN
07/31/18
Crystal structure of the E148D mutant CLC-ec1 in 50 mM bromide
ESCHERICHIA COLI (STRAIN K12); MUS MUSCULUS
mus musculus
mus musculus
escherichia coli (strain k12)
Lim, H.-H., Park, K.
3.3
X-RAY DIFFRACTION
0.284
0.227
false
false
IGHV4
IGKV4
Kappa
null
null
null
null
null
7zmv
F
null
0
B
protein
null
atp-dependent dna helicase q5
HYDROLASE
04/19/22
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G5-006
Homo sapiens; Lama glama
lama glama
null
homo sapiens
Ye, M., Makola, M., Newman, J.A., Fairhead, M., MacLean, E., Krojer, T., Aitkenhead, H., Bountra, C., Gileadi, O., von Delft, F.
2.002
X-RAY DIFFRACTION
0.275
0.242
false
true
IGHV1
null
null
null
null
null
null
null
6x1s
H
L
0
I
peptide
null
nm23-1-ptza peptide
IMMUNE SYSTEM
05/19/20
Structure of pHis Fab (SC1-1) in complex with pHis mimetic peptide
ORYCTOLAGUS CUNICULUS; SYNTHETIC CONSTRUCT
oryctolagus cuniculus
oryctolagus cuniculus
synthetic construct
Kalagiri, R., Stanfield, R.L., Wilson, I.A., Hunter, T.
1.65
X-RAY DIFFRACTION
0.226
0.200
false
true
IGHV1
IGKV1
Kappa
null
null
null
null
null
3mlw
I
M
0
Q
peptide
null
hiv-1 gp120 third variable region (v3) crown
IMMUNE SYSTEM
04/18/10
Crystal structure of anti-HIV-1 V3 Fab 1006-15D in complex with an MN V3 peptide
HIV-1 M:B_MN; HOMO SAPIENS
homo sapiens
homo sapiens
hiv-1 m
Kong, X.-P.
2.7
X-RAY DIFFRACTION
0.291
0.214
false
false
IGHV5
IGLV1
Lambda
null
null
null
null
null
6mzj
D
C
0
B
protein
null
426c ds-sosip d3
VIRAL PROTEIN/IMMUNE SYSTEM
11/05/18
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1
Borst, A.J., Weidle, C.E., Gray, M.D., Frenz, B., Snijder, J., Joyce, M.G., Georgiev, I.S., Stewart-Jones, G.B.E., Kwong, P.D., McGuire, A.T., DiMaio, F., Stamatatos, L., Pancera, M., Veesler, D.
4.8
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
3gi9
H
L
0
C
protein
null
uncharacterized protein mj0609
TRANSPORT PROTEIN
03/05/09
Crystal Structure of ApcT Transporter Bound to 7F11 Monoclonal Fab Fragment
MUS MUSCULUS; METHANOCALDOCOCCUS JANNASCHII
mus musculus
mus musculus
methanocaldococcus jannaschii
Shaffer, P.L., Goehring, A.S., Shankaranarayanan, A., Gouaux, E., New York Consortium on Membrane Protein Structure (NYCOMPS)
2.48
X-RAY DIFFRACTION
0.296
0.248
false
true
IGHV1
IGKV8
Kappa
null
null
null
null
null
5iq9
H
L
0
P
peptide
null
gp41 mper peptide
IMMUNE SYSTEM
03/10/16
Crystal structure of 10E8v4 Fab in complex with an HIV-1 gp41 peptide.
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
human immunodeficiency virus 1
Ofek, G., Kwon, Y.D., Caruso, W., Kwong, P.D.
2.4
X-RAY DIFFRACTION
0.236
0.191
false
true
IGHV3
IGLV3
Lambda
null
null
null
null
null
7f46
H
L
0
B | C
protein | protein
NA | NA
spike glycoprotein | spike glycoprotein
VIRAL PROTEIN
06/17/21
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab (state1, local refinement of the RBD, NTD and 35B5 Fab)
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2 | severe acute respiratory syndrome coronavirus2
Wang, X.F., Zhu, Y.Q.
4.79
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV2
Kappa
null
null
null
null
null
2gcy
B
A
0
null
null
null
null
IMMUNE SYSTEM
03/14/06
humanized antibody C25 Fab fragment
MUS MUSCULUS
mus musculus
mus musculus
null
LaPorte, S.L., Finer-Moore, J., Marks, J.D., Forsyth, C.M.
2.5
X-RAY DIFFRACTION
0.232
0.225
false
true
IGHV5
IGKV3
Kappa
null
null
null
null
null
7e6p
H
L
0
A
peptide
null
amyloid beta fragment with an intramolecular disulfide bondat positions 17 and 28
IMMUNE SYSTEM
02/23/21
Fab-amyloid beta fragment complex
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
homo sapiens
Kita, A., Irie, K., Irie, Y., Miki, K.
2.5
X-RAY DIFFRACTION
0.244
0.191
false
false
IGHV1
IGKV8
Kappa
null
null
null
null
null
4zg1
A
null
0
null
null
null
null
PROTEIN BINDING
04/22/15
Crystal structure of a nanobody raised against KDM5b
LAMA GLAMA
lama glama
null
null
Wiuf, A., Kristensen, O., Gajhede, M.
1.85
X-RAY DIFFRACTION
0.235
0.186
false
true
IGHV1
null
null
null
null
null
null
null
6mi2
A
B
0
C
protein
null
tumor necrosis factor receptor superfamily member 9
IMMUNE SYSTEM
09/19/18
Structure of the human 4-1BB / Utomilumab Fab complex
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Kimberlin, C.R., Chin, S.M., Roe-Zurz, Z., Xu, A., Yang, Y.
2.72
X-RAY DIFFRACTION
0.278
0.238
false
true
IGHV5
IGLV3
Lambda
0
-9.769558
SPR
null
TBD
7jv5
N
null
0
A | B | G
protein | protein | protein
NA | NA | NA
guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2
SIGNALING PROTEIN
08/20/20
Cryo-EM structure of SKF-81297-bound dopamine receptor 1 in complex with Gs protein
HOMO SAPIENS; SYNTHETIC CONSTRUCT
synthetic construct
null
homo sapiens | homo sapiens | homo sapiens
Zhuang, Y., Xu, P., Mao, C., Wang, L., Krumm, B., Zhou, X.E., Huang, S., Liu, H., Cheng, X., Huang, X.-P., Sheng, D.-D., Xu, T., Liu, Y.-F., Wang, Y., Guo, J., Jiang, Y., Jiang, H., Melcher, K., Roth, B.L., Zhang, Y., Zhang, C., Xu, H.E.
3
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
null
null
null
null
null
null
null
7qji
F
null
0
E
protein
null
divalent metal cation transporter
MEMBRANE PROTEIN
12/16/21
X-Ray Structure of apo-EleNRMT in complex with two Nanobodies at 4.1A
EGGERTHELLA LENTA
eggerthella lenta
null
eggerthella lenta
Ramanadane, K., Straub, M.S., Dutzler, R., Manatschal, C.
4.1
X-RAY DIFFRACTION
0.316
0.267
false
true
IGHV1
null
null
null
null
null
null
null
3eba
A
null
0
B
protein
null
lysozyme c
IMMUNE SYSTEM/HYDROLASE
08/27/08
CAbHul6 FGLW mutant (humanized) in complex with human lysozyme
CAMELUS DROMEDARIUS; HOMO SAPIENS
camelus dromedarius
null
homo sapiens
Loris, R., Vincke, C., Saerens, D., Martinez-Rodriguez, S., Muyldermans, S., Conrath, K.
1.85
X-RAY DIFFRACTION
0.255
0.211
false
true
IGHV1
null
null
0
-11.76
SPR
null
19010777
5uoe
H
L
0
A
protein
null
insulin-degrading enzyme
Hydrolase/Immune System
01/31/17
Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE)
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Liang, W.G., Bailey, L., Kossiakoff, T., Tang, W.J.
3.8
X-RAY DIFFRACTION
0.270
0.220
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
7vui
N
null
0
A | B
protein | protein
NA | NA
isoform gnas-2 of guanine nucleotide-binding protein g(s)subunit alpha isoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1
MEMBRANE PROTEIN
11/02/21
Cryo-EM structure of a class A orphan GPCR
HOMO SAPIENS; BACILLUS CIRCULANS
homo sapiens
null
homo sapiens | homo sapiens
Liu, Z.J., Hua, T., Zhou, Y.L., Wu, L.J.
3.3
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
null
null
null
null
null
null
null
2qqk
H
L
0
A
protein
null
neuropilin-2
SIGNALING PROTEIN
07/26/07
Neuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking Fab
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Appleton, B.A., Wiesmann, C.
2.75
X-RAY DIFFRACTION
0.243
0.186
false
true
IGHV3
IGKV1D
Kappa
null
null
null
null
null
4m1d
H
L
0
P
peptide
null
cyclic v3 arch peptide
IMMUNE SYSTEM
08/02/13
Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 cyclic peptide MN
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
null
Killikelly, A., Kong, X.P.
1.8
X-RAY DIFFRACTION
0.216
0.186
false
true
IGHV3
IGLV1
Lambda
0
-10.420468
Unknown
null
TBD
4xph
H
L
0
A
protein
null
transporter
protein transport/inhibitor
01/17/15
X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to 3,4dichlorophenethylamine
MUS MUSCULUS; DROSOPHILA MELANOGASTER
mus musculus
mus musculus
drosophila melanogaster
Penmatsa, A., Wang, K., Gouaux, E.
2.9
X-RAY DIFFRACTION
0.277
0.240
false
true
IGHV5
IGKV4
Kappa
null
null
null
null
null
7sob
C
B
0
A
protein
null
spike glycoprotein
VIRAL PROTEIN/IMMUNE SYSTEM
10/29/21
SARS-CoV-2 S B.1.617.1 kappa variant + S309 + S2L20 Global Refinement
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
2.4
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
4r4n
T
U
0
S
protein
null
m48u1 peptide
VIRAL PROTEIN/IMMUNE SYSTEM/INHIBITOR
08/19/14
Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
human immunodeficiency virus 1
Acharya, P., Louder, R., Kwong, P.D.
3.56
X-RAY DIFFRACTION
0.328
0.296
false
true
IGHV4
IGKV1
Kappa
null
null
null
null
null
7vsu
B
A
0
null
null
null
null
BIOSYNTHETIC PROTEIN
10/27/21
Crystal structure of Fab fragment of anti-mesothelin antibody
HOMO SAPIENS
homo sapiens
homo sapiens
null
Yang, Z., Ying, T.
3.1
X-RAY DIFFRACTION
0.249
0.215
false
true
IGHV4
IGKV1
Kappa
null
null
null
null
null
3efd
H
L
0
K
peptide
null
kcsa
IMMUNE SYSTEM
09/08/08
The crystal structure of the cytoplasmic domain of KcsA
MUS MUSCULUS; ESCHERICHIA COLI
mus musculus
mus musculus
escherichia coli
Uysal, S., Vasquez, V., Tereshko, V., Esaki, K., Fellouse, F.A., Sidhu, S.S., Koide, S., Perozo, E., Kossiakoff, A.
2.6
X-RAY DIFFRACTION
0.276
0.225
false
false
IGHV3
IGKV1
Kappa
null
null
null
null
null
3j8w
G
K
0
C
protein
null
l1
VIRUS/IMMUNE SYSTEM
11/19/14
Cryo-EM reconstruction of quasi-HPV16 complex with H263.A2 Fab
MUS MUSCULUS; HUMAN PAPILLOMAVIRUS TYPE 16
mus musculus
mus musculus
human papillomavirus type 16
Guan, J., Hafenstein, S.
13
ELECTRON MICROSCOPY
null
null
false
false
IGHV1
IGKV12
Kappa
null
null
null
null
null
3rpi
A
B
0
null
null
null
null
IMMUNE SYSTEM
04/26/11
Crystal Structure of Fab from 3BNC60, Highly Potent anti-HIV Antibody
HOMO SAPIENS
homo sapiens
homo sapiens
null
Diskin, R., Bjorkman, P.J.
2.648
X-RAY DIFFRACTION
0.258
0.208
false
true
IGHV1
IGKV1
Kappa
null
null
null
null
null
7nc0
H
L
0
null
null
null
null
IMMUNE SYSTEM
01/28/21
The structure of the humanised A33 Fab C226S variant, an immunotherapy candidate for colorectal cancer
HOMO SAPIENS
homo sapiens
homo sapiens
null
Tang, J., Zhang, C., Dalby, P., Kozielski, F.
2.2
X-RAY DIFFRACTION
0.257
0.215
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
3be1
H
L
0
A
protein
null
receptor tyrosine-protein kinase erbb-2
TRANSFERASE
11/15/07
Dual specific bH1 Fab in complex with the extracellular domain of HER2/ErbB-2
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Bostrom, J.M., Wiesmann, C., Appleton, B.A.
2.9
X-RAY DIFFRACTION
0.277
0.236
false
true
IGHV3
IGKV1
Kappa
0
-10.34
SPR
null
19299620
4zpv
H
L
0
R
protein
null
spike glycoprotein
VIRAL PROTEIN/IMMUNE SYSTEM
05/08/15
Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)
HUMAN CORONAVIRUS EMC (ISOLATE UNITED KINGDOM/H123990006/2012); MUS MUSCULUS
mus musculus
mus musculus
human coronavirus emc (isolate unitedkingdom/h123990006/2012)
Joyce, M.G., Mascola, J.R., Graham, B.S., Kwong, P.D.
3.2
X-RAY DIFFRACTION
0.281
0.223
false
false
IGHV5
IGKV10
Kappa
null
null
null
null
null
6y97
H
L
0
A | B
protein | protein
NA | NA
b-lymphocyte antigen cd20 | b-lymphocyte antigen cd20
MEMBRANE PROTEIN
03/06/20
Structure of full-length CD20 in complex with Obinutuzumab Fab
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens | homo sapiens
Kumar, A., Reyes, N.
4.33
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
IGKV2
Kappa
null
null
null
null
null
6xw6
C
null
0
A
protein
null
capsid protein
VIRAL PROTEIN
01/23/20
Crystal structure of murine norovirus P domain in complex with Nanobody NB-5853
MURINE NOROVIRUS 1; VICUGNA PACOS
vicugna pacos
null
murine norovirus 1
Kilic, T., Sabin, C., Hansman, G.
1.96
X-RAY DIFFRACTION
0.248
0.199
false
true
IGHV1
null
null
null
null
null
null
null
4grw
I
null
0
D
protein
null
interleukin-12 subunit beta
IMMUNE SYSTEM
08/27/12
Structure of a complex of human IL-23 with 3 Nanobodies (Llama vHHs)
LLAMA GLAMA; HOMO SAPIENS; SYNTHETIC CONSTRUCT
lama glama
null
homo sapiens
Desmyter, A., Spinelli, S., Button, C., Saunders, M., de Haard, H., Rommelaere, H., Union, A., Cambillau, C.
2.55
X-RAY DIFFRACTION
0.218
0.183
false
true
IGHV1
null
null
null
null
null
null
null
7e9n
H
L
0
A
protein
null
spike glycoprotein
VIRAL PROTEIN,IMMUNE SYSTEM
03/04/21
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 down RBD, state1)
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Wang, X.F., Zhu, Y.Q.
3.69
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV2
Kappa
null
null
null
null
null
6war
L
null
0
K
protein
null
spike protein
VIRAL PROTEIN/IMMUNE SYSTEM
04/08/20
Crystal structure of the MERS-CoV RBD bound by the neutralizing single-domain antibody MERS VHH-55
MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS; LAMA GLAMA
lama glama
null
middle east respiratory syndrome-relatedcoronavirus
Wrapp, D., Torres, G.M., McLellan, J.S.
3.4
X-RAY DIFFRACTION
0.268
0.214
false
true
IGHV1
null
null
null
null
null
null
null
4grw
J
null
0
A
protein
null
interleukin-23 subunit alpha
IMMUNE SYSTEM
08/27/12
Structure of a complex of human IL-23 with 3 Nanobodies (Llama vHHs)
LLAMA GLAMA; HOMO SAPIENS; SYNTHETIC CONSTRUCT
lama glama
null
homo sapiens
Desmyter, A., Spinelli, S., Button, C., Saunders, M., de Haard, H., Rommelaere, H., Union, A., Cambillau, C.
2.55
X-RAY DIFFRACTION
0.218
0.183
false
true
IGHV1
null
null
null
null
null
null
null
5dmg
C
D
0
Z
peptide
null
microtubule-associated protein
IMMUNE SYSTEM
09/08/15
X-RAY STRUCTURE OF THE FAB FRAGMENT OF THE ANTI TAU ANTIBODY RB86 IN COMPLEX WITH THE PHOSPHORYLATED TAU PEPTIDE (416-430)
ORYCTOLAGUS CUNICULUS; SYNTHETIC CONSTRUCT
oryctolagus cuniculus
oryctolagus cuniculus
homo sapiens
Benz, J., Lorenz, S., Georges, G., Jochner, A., Goepfert, U., Grueninger, F., Bujotzek, A.
2.5
X-RAY DIFFRACTION
0.263
0.210
false
true
IGHV1
IGKV1
Kappa
null
null
null
null
null
6e5p
R
Q
0
R
carbohydrate
NAG
polysaccharide
VIRAL PROTEIN
07/21/18
Backbone model based on cryo-EM map at 8.5 A of domain-swapped, glycan-reactive, neutralizing antibody 2G12 bound to HIV-1 Env BG505 DS-SOSIP, which was also bound to CD4-binding site antibody VRC03
HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1
homo sapiens
homo sapiens
homo sapiens
Acharya, P., Kwong, P.D.
8.8
ELECTRON MICROSCOPY
null
null
false
true
unknown
IGKV1
Kappa
null
null
null
null
null
7lf7
H
L
0
K
protein
null
apolipoprotein l1
IMMUNE SYSTEM
01/15/21
Fab 6D12 bound to ApoL1 NTD
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Ultsch, M., Kirchhofer, D.
2.026
X-RAY DIFFRACTION
0.217
0.189
false
true
IGHV5
IGKV16
Kappa
null
null
null
null
null
5vxm
B
null
0
A
protein
null
invasin ipad
IMMUNE SYSTEM
05/23/17
2.05 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody 20ipaD
SHIGELLA FLEXNERI; VICUGNA PACOS
vicugna pacos
null
shigella flexneri
Barta, M.L., Lovell, S., Battaile, K.P., Picking, W.D., Picking, W.L.
2.05
X-RAY DIFFRACTION
0.246
0.210
false
true
IGHV1
null
null
null
null
null
null
null
6vy4
H
L
0
A
protein
null
receptor binding protein
VIRAL PROTEIN/IMMUNE SYSTEM
02/25/20
Crystal structure of Hendra receptor binding protein head domain in complex with human neutralizing antibody HENV-32
HENDRA HENIPAVIRUS; HOMO SAPIENS
homo sapiens
homo sapiens
hendra henipavirus
Dong, J., Crowe, J.E.
2.0
X-RAY DIFFRACTION
0.226
0.183
false
true
IGHV1
IGLV3
Lambda
null
null
null
null
null
1r3i
H
L
0
C
protein
null
voltage-gated potassium channel
MEMBRANE PROTEIN
10/02/03
potassium channel KcsA-Fab complex in Rb+
STREPTOMYCES LIVIDANS; MUS MUSCULUS
mus musculus
mus musculus
streptomyces lividans
Zhou, Y., MacKinnon, R.
2.4
X-RAY DIFFRACTION
0.236
0.217
false
false
IGHV1
IGKV5
Kappa
null
null
null
null
null
7wd7
a
b
0
A
protein
null
heavy chain of s5d2 fab
VIRAL PROTEIN
12/21/21
SARS-CoV-2 Beta spike in complex with three S5D2 Fabs
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS
mus musculus
mus musculus
severe acute respiratory syndrome coronavirus2
Wang, Y.F., Cong, Y.
3.5
ELECTRON MICROSCOPY
null
null
false
false
IGHV1
IGKV8
Kappa
null
null
null
null
null
5vm6
A
null
0
A
Hapten
9EG
N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea
UNKNOWN FUNCTION
04/26/17
The hapten triclocarban bound to the single domain camelid nanobody VHH T10
LAMA GLAMA
lama glama
null
lama glama
Tabares-da Rosa, S., Gonzalez-Sapienza, G., Wilson, D.K.
1.5
X-RAY DIFFRACTION
0.193
0.172
false
true
unknown
unknown
unknown
null
null
null
null
null
5esz
H
L
0
G
protein
null
2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthase,envelope glycoprotein gp160
IMMUNE SYSTEM
11/17/15
Crystal Structure of Broadly Neutralizing Antibody CH04, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade AE Strain A244
HOMO SAPIENS; HAEMOPHILUS INFLUENZAE
homo sapiens
homo sapiens
haemophilus influenzae, human immunodeficiencyvirus 1, haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
Gorman, J., Yang, M., Kwong, P.D.
4.191
X-RAY DIFFRACTION
0.282
0.252
false
true
IGHV3
IGKV3
Kappa
null
null
null
null
null
3ria
G
K
0
C
protein
null
avermectin-sensitive glutamate-gated chloride channel gluclalpha
TRANSPORT PROTEIN/IMMUNE SYSTEM
04/13/11
C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and iodide.
CAENORHABDITIS ELEGANS; MUS MUSCULUS
mus musculus
mus musculus
caenorhabditis elegans
Hibbs, R.E., Gouaux, E.
3.8
X-RAY DIFFRACTION
0.280
0.266
false
true
IGHV1
IGLV1
Lambda
null
null
null
null
null
7p5y
G
null
0
A
protein
null
volume-regulated anion channel subunit lrrc8a
MEMBRANE PROTEIN
07/15/21
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb3
MUS MUSCULUS; SYNTHETIC CONSTRUCT
synthetic construct
null
mus musculus
Deneka, D., Rutz, S., Sawicka, M.
3.29
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
7lyw
A
B
0
null
null
null
null
IMMUNE SYSTEM
03/08/21
Crystal structure of the HCMV pentamer-specific antibody 2-25
HOMO SAPIENS
homo sapiens
homo sapiens
null
Wrapp, D., Mishra, A.K., McLellan, J.S.
2.51
X-RAY DIFFRACTION
0.219
0.187
false
true
IGHV1
IGLV3
Lambda
null
null
null
null
null
1wtl
null
A
0
null
null
null
null
IMMUNOGLOBULIN
06/08/94
COMPARISON OF CRYSTAL STRUCTURES OF TWO HOMOLOGOUS PROTEINS: STRUCTURAL ORIGIN OF ALTERED DOMAIN INTERACTIONS IN IMMUNOGLOBULIN LIGHT CHAIN DIMERS
HOMO SAPIENS
null
homo sapiens
null
Huang, D.B., Chang, C.H., Schiffer, M.
1.9
X-RAY DIFFRACTION
unknown
unknown
false
true
null
IGKV1
Kappa
null
null
null
null
null
5jds
B
null
0
A
protein
null
programmed cell death 1 ligand 1
IMMUNE SYSTEM
04/17/16
Crystal structure of PD-L1 complexed with a nanobody at 1.7 Angstron resolution
CAMELIDAE; HOMO SAPIENS
camelidae
null
homo sapiens
Zhou, A., Wei, H.
1.7
X-RAY DIFFRACTION
0.204
0.178
false
true
IGHV1
null
null
0
-11.627287
SPR
null
TBD
2mmx
null
A
16
null
null
null
null
IMMUNE SYSTEM
03/20/14
NMR study of 6aJL2
HOMO SAPIENS
null
homo sapiens
null
Amero, C., Maya-Martinez, R.C., Gil-Rodriguez, P.C.
NOT
SOLUTION NMR
null
null
false
true
null
IGLV6
Lambda
null
null
null
null
null
7k7i
H
L
0
A
protein
null
putative pertussis-like toxin subunit
TOXIN
09/22/20
Density-fitted Model Structure of Antibody Variable Domains of TyTx4 in Complex with PltB pentamer of Typhoid Toxin
SALMONELLA TYPHI; MUS MUSCULUS
mus musculus
mus musculus
salmonella typhi
Nguyen, T., Feathers, J.R., Fromme, J.C., Song, J.
3.13
ELECTRON MICROSCOPY
null
null
false
true
IGHV5
IGKV5
Kappa
null
null
null
null
null
1wcb
B
A
0
null
null
null
null
IMMUNE SYSTEM
11/12/04
PLP-DEPENDENT CATALYTIC ANTIBODY 15A9 IN COMPLEX WITH ITS HAPTEN
MUS MUSCULUS
mus musculus
mus musculus
null
Pimpaneau, Beatrice Golinelli-, Christen, P.
2.5
X-RAY DIFFRACTION
0.2899
0.2230
false
true
IGHV7
IGKV4
Kappa
null
null
null
null
null
2qr0
N
M
0
O
protein
null
vascular endothelial growth factor a
IMMUNE SYSTEM
07/27/07
Structure of VEGF complexed to a Fab containing TYR and SER in the CDRs
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Wiesmann, C.
3.5
X-RAY DIFFRACTION
0.312
0.291
false
false
IGHV3
IGKV1
Kappa
0
-11.5
SPR
37
17825836
3s96
C
D
0
null
null
null
null
IMMUNE SYSTEM
05/31/11
Crystal structure of 3B5H10
MUS MUSCULUS
mus musculus
mus musculus
null
Weisgraber, K., Peters-Libeu, C., Rutenber, E., Newhouse, Y., Finkbeiner, S.
1.9
X-RAY DIFFRACTION
0.260
0.183
false
false
IGHV9
IGLV3
Lambda
null
null
null
null
null
1mfb
H
L
0
H
carbohydrate
GLA
polysaccharide
IMMUNOGLOBULIN
10/25/93
HIGH RESOLUTION STRUCTURES OF ANTIBODY FAB FRAGMENT COMPLEXED WITH CELL-SURFACE OLIGOSACCHARIDE OF PATHOGENIC SALMONELLA
MUS MUSCULUS
mus musculus
mus musculus
mus musculus
Zdanov, A., Cygler, M.
2.1
X-RAY DIFFRACTION
unknown
0.160
false
true
IGHV1
IGLV1
Lambda
null
null
null
null
null
7mfg
E
F
0
D | C
protein | protein
NA | NA
hemagglutinin ha2 chain | hemagglutinin ha1 chain
VIRAL PROTEIN/IMMUNE SYSTEM
04/09/21
Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer
INFLUENZA A VIRUS; HOMO SAPIENS
homo sapiens
homo sapiens
influenza a virus | influenza a virus
Gorman, J., Kwong, P.D.
3.87
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
6pcu
I
H
0
G
protein
null
outer capsid protein vp4
viral protein/immune system
06/18/19
VP8* of a G2P[4] human rotavirus in complex with scFv antibody 9
ROTAVIRUS A; HOMO SAPIENS
homo sapiens
homo sapiens
rotavirus a
Hu, L., Venkataram Prasad, B.V.
2.4
X-RAY DIFFRACTION
0.237
0.186
false
true
IGHV4
IGLV9
Lambda
null
null
null
null
null
6n81
C
D
0
B
protein
null
major capsid protein
IMMUNE SYSTEM
11/28/18
Crystal structure of GII.4 2002 norovirus P domain in complex with cross-reactive human antibody A1227
NOROVIRUS HU/GII.4/FARMINGTON HILLS/2004/USA; HOMO SAPIENS
homo sapiens
homo sapiens
norovirus hu/gii.4/farmington hills/2004/usa
Changela, A., Verardi, R., Kwong, P.D.
2.579
X-RAY DIFFRACTION
0.211
0.173
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
1bww
null
A
0
null
null
null
null
IMMUNE SYSTEM
09/29/98
BENCE-JONES IMMUNOGLOBULIN REI VARIABLE PORTION, T39K MUTANT
HOMO SAPIENS
null
homo sapiens
null
Uson, I., Pohl, E., Schneider, T.R., Dauter, Z., Schmidt, A., Fritz, H.J., Sheldrick, G.M.
1.7
X-RAY DIFFRACTION
unknown
unknown
false
true
null
IGKV1
Kappa
null
null
null
null
null
1hzh
H
L
0
null
null
null
null
IMMUNE SYSTEM
01/24/01
CRYSTAL STRUCTURE OF THE INTACT HUMAN IGG B12 WITH BROAD AND POTENT ACTIVITY AGAINST PRIMARY HIV-1 ISOLATES: A TEMPLATE FOR HIV VACCINE DESIGN
HOMO SAPIENS
homo sapiens
homo sapiens
null
Saphire, E.O., Burton, D.R., Wilson, I.A.
2.7
X-RAY DIFFRACTION
0.273
0.229
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
4zpv
A
B
0
S
protein
null
spike glycoprotein
VIRAL PROTEIN/IMMUNE SYSTEM
05/08/15
Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)
HUMAN CORONAVIRUS EMC (ISOLATE UNITED KINGDOM/H123990006/2012); MUS MUSCULUS
mus musculus
mus musculus
human coronavirus emc (isolate unitedkingdom/h123990006/2012)
Joyce, M.G., Mascola, J.R., Graham, B.S., Kwong, P.D.
3.2
X-RAY DIFFRACTION
0.281
0.223
false
false
IGHV5
IGKV10
Kappa
null
null
null
null
null
1f8t
H
L
0
null
null
null
null
IMMUNE SYSTEM
07/05/00
FAB (LNKB-2) OF MONOCLONAL ANTIBODY, CRYSTAL STRUCTURE
MUS MUSCULUS
mus musculus
mus musculus
null
Fokin, A.V., Afonin, P.V., Mikhailova, I.I., Tsygannik, I.N., Mareeva, T.I.
2.2
X-RAY DIFFRACTION
0.221
0.171
false
false
IGHV3
IGKV1
Kappa
null
null
null
null
null
7wec
G
J
0
B
protein
null
spike glycoprotein
IMMUNE SYSTEM/VIRAL PROTEIN
12/23/21
SARS-CoV-2 Omicron variant spike protein with three XGv347 Fabs binding to three closed state RBDs
HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Wang, X., Wang, L.
3.3
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
4r7n
K
L
0
null
null
null
null
IMMUNE SYSTEM
08/28/14
Fab C2E3
HOMO SAPIENS
homo sapiens
homo sapiens
null
Loyau, J., Didelot, G., Malinge, P., Ravn, U., Magistrelli, G., Depoisier, J.F., Kosco-Vilbois, M., Fischer, N., Thore, S., Rousseau, F.
3.45
X-RAY DIFFRACTION
0.280
0.236
false
true
IGHV4
IGKV6
Kappa
null
null
null
null
null
6iw2
B
C
0
A
protein
null
envelope protein e
VIRAL PROTEIN/IMMUNE SYSTEM
12/04/18
Crystal structure of 5A ScFv in complex with YFV-17D sE in prefusion state
YELLOW FEVER VIRUS (STRAIN 17D VACCINE); HOMO SAPIENS
homo sapiens
homo sapiens
yellow fever virus (strain 17d vaccine)
Lu, X.S., Xiao, H.X., Li, S.H., Pang, X.F.
2.9
X-RAY DIFFRACTION
0.272
0.238
false
true
IGHV4
IGKV1
Kappa
null
null
null
null
null
2qtj
C
O
3
null
null
null
null
IMMUNE SYSTEM
08/02/07
Solution structure of human dimeric immunoglobulin A
HOMO SAPIENS
homo sapiens
homo sapiens
null
Bonner, A., Furtado, P.B., Almogren, A., Kerr, M.A., Perkins, S.J.
NOT
SOLUTION SCATTERING
null
null
false
false
IGHV1
IGKV1
Kappa
null
null
null
null
null
7djy
A
null
0
null
null
null
null
BIOSYNTHETIC PROTEIN
11/22/20
Clec4f Nanobody 322
LAMIUM MACULATUM
lamium maculatum
null
null
Wen, Y., Zheng, F.
2.7
X-RAY DIFFRACTION
0.266
0.228
false
true
IGHV1
null
null
null
null
null
null
null
3ntc
H
L
0
null
null
null
null
IMMUNE SYSTEM
07/03/10
Crystal structure of KD-247 Fab, an anti-V3 antibody that inhibits HIV-1 Entry
HOMO SAPIENS, MUS MUSCULUS
homo sapiens, mus musculus
homo sapiens, mus musculus
null
Sarafianos, S.G., Kirby, K.A.
1.55
X-RAY DIFFRACTION
0.222
0.182
false
true
IGHV1
IGKV8
Kappa
null
null
null
null
null
6woz
H
I
0
G
protein
null
reticulocyte binding protein 2b
CELL INVASION
04/26/20
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 251249
PLASMODIUM VIVAX (STRAIN SALVADOR I); HOMO SAPIENS
homo sapiens
homo sapiens
plasmodium vivax (strain salvador i)
Chan, L.J., Dietrich, M.H., Tham, W.H.
2.9
X-RAY DIFFRACTION
0.258
0.211
false
true
IGHV3
IGKV3
Kappa
null
null
null
null
null
1ce1
H
L
0
P
peptide
null
protein (peptide antigen)
IMMUNE SYSTEM
03/12/99
1.9A STRUCTURE OF THE THERAPEUTIC ANTIBODY CAMPATH-1H FAB IN COMPLEX WITH A SYNTHETIC PEPTIDE ANTIGEN
HOMO SAPIENS; SYNTHETIC CONSTRUCT
null
null
null
James, L.C., Hale, G., Waldmann, H., Bloomer, A.C.
1.9
X-RAY DIFFRACTION
0.270
0.220
false
true
IGHV4
IGKV1
Kappa
null
null
null
null
null
4wht
X
Y
0
x
peptide
null
unknown
VIRAL PROTEIN
09/23/14
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P1 crystal form
HEPATITIS C VIRUS; RATTUS NORVEGICUS
rattus norvegicus
rattus norvegicus
hepatitis c virus
Krey, T., Rey, F.A.
2.22
X-RAY DIFFRACTION
0.243
0.209
false
true
IGHV5
IGKV2
Kappa
0
-11.053614
Unknown
null
TBD
3ze0
E
F
0
C
protein
null
integrin alpha-iib
CELL ADHESION/IMMUNE SYSTEM/PEPTIDE
12/03/12
Integrin alphaIIB beta3 headpiece and RGD peptide complex
MUS MUSCULUS; HOMO SAPIENS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
homo sapiens
Zhu, J.H., Zhu, J.Q., Springer, T.A.
2.95
X-RAY DIFFRACTION
0.2427
0.1847
false
true
IGHV14
IGKV14
Kappa
null
null
null
null
null