pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
6fys | D | null | 0 | null | null | null | null | VIRAL PROTEIN | 03/12/18 | Structure of single domain antibody SD83 | LAMA GLAMA | lama glama | null | null | Laursen, N.S., Wilson, I.A. | 2.0 | X-RAY DIFFRACTION | 0.231 | 0.201 | false | true | IGHV1 | null | null | null | null | null | null | null |
7lkb | H | L | 0 | A | peptide | null | circumsporozoite protein | IMMUNE SYSTEM/ANTIGEN | 02/02/21 | Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.127 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum 3d7 | Xu, K., Kwong, P.D. | 1.8 | X-RAY DIFFRACTION | 0.217 | 0.181 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
7kex | I | L | 0 | C | protein | null | virion spike glycoprotein 1 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/13/20 | Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-293 | HOMO SAPIENS; EBOLA VIRUS | homo sapiens | homo sapiens | ebola virus | Murin, C.D., Ward, A.B. | 4.25 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5ocl | B | null | 0 | null | null | null | null | IMMUNE SYSTEM | 07/03/17 | Nanobody-anti-VGLUT nanobody complex | VICUGNA PACOS; LAMA GLAMA | lama glama | null | null | Dutzler, R., Schenck, S., Kunz, L. | 2.2 | X-RAY DIFFRACTION | 0.208 | 0.188 | false | true | IGHV1 | null | null | null | null | null | null | null |
6mhr | D | E | 0 | F | protein | null | tumor necrosis factor receptor superfamily member 9 | IMMUNE SYSTEM | 09/18/18 | Structure of the human 4-1BB / Urelumab Fab complex | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Kimberlin, C.R., Chin, S.M., Roe-Zurz, Z., Xu, A., Yang, Y. | 2.8 | X-RAY DIFFRACTION | 0.222 | 0.200 | false | true | IGHV4 | IGKV3 | Kappa | 0 | -10.446805 | SPR | null | TBD |
7t0k | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 11/29/21 | Crystal structure of S25-2 Fab Unliganded 4 | MUS MUSCULUS | mus musculus | mus musculus | null | Legg, M.S.G., Blackler, R.J., Evans, S.V. | 2.0 | X-RAY DIFFRACTION | 0.255 | 0.222 | false | true | IGHV7 | IGKV8 | Kappa | null | null | null | null | null |
4fqr | o | p | 0 | O | protein | null | broadly neutralizing antibody c05, heavy chain | VIRAL PROTEIN/IMMUNE SYSTEM | 06/25/12 | Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Ekiert, D.C., Wilson, I.A. | 4.1 | X-RAY DIFFRACTION | 0.334 | 0.309 | false | false | IGHV3 | IGKV1 | Kappa | 0 | -9.549709 | SPR | null | TBD |
7d85 | B | C | 0 | A | protein | null | receptor tyrosine-protein kinase erbb-3 | IMMUNE SYSTEM | 10/07/20 | Crystal structure of anti-ErbB3 Fab ISU104 in complex with human ErbB3 extracellular domain 3 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Yoo, Y., Cho, H.S. | 2.5 | X-RAY DIFFRACTION | 0.258 | 0.203 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7lj5 | E | D | 0 | A | protein | null | isoform 2 of potassium channel subfamily k member 4 | METAL TRANSPORT/Immune System | 01/28/21 | Human TRAAK K+ channel FHIEG mutant A198E in a K+ bound conductive conformation | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Rietmeijer, R.A., Brohawn, S.G. | 2.26 | X-RAY DIFFRACTION | 0.252 | 0.220 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
5uk4 | t | null | 0 | T | protein | null | anti-vesicular stomatitis virus n vhh | Viral Protein/RNA/Immune System | 01/19/17 | VESICULAR STOMATITS VIRUS N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1307 | VESICULAR STOMATITIS INDIANA VIRUS (STRAIN SAN JUAN); VICUGNA PACOS | vicugna pacos | null | vesicular stomatitis indiana virus (strain sanjuan) | Hanke, L., Knockenhauer, K.E., Ploegh, H.L., Schwartz, T.U. | 3.204 | X-RAY DIFFRACTION | 0.288 | 0.237 | false | false | IGHV1 | null | null | null | null | null | null | null |
4f58 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/12/12 | Fab structure of a neutralizing antibody L3 from an early subtype A HIV-1 infected patient | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pan, R.M., Kong, X.P. | 2.488 | X-RAY DIFFRACTION | 0.256 | 0.208 | false | false | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
4ej1 | C | null | 0 | B | protein | null | dihydrofolate reductase | Oxidoreductase/Immune system | 04/06/12 | Binding of Nb113 camelid antibody fragment with the binary DHFR:folate complex | ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | escherichia coli | Oyen, D., Srinivasan, V. | 1.75 | X-RAY DIFFRACTION | 0.224 | 0.186 | false | true | IGHV1 | null | null | null | null | null | null | null |
4at6 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 05/04/12 | Fab fragment of antiporphyrin antibody 14H7 | MUS MUSCULUS | mus musculus | mus musculus | null | Golinelli-Pimpaneau, B., Mahy, J.P. | 2.549 | X-RAY DIFFRACTION | 0.3281 | 0.2791 | false | false | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7ws7 | G | F | 0 | B | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/28/22 | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Guo, H., Gao, Y., Ji, X., Yang, H. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7lf0 | K | L | 0 | N | protein | null | arginase-1 | HYDROLASE/IMMUNE SYSTEM | 01/15/21 | Trimeric human Arginase 1 in complex with mAb2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gomez-Llorente, Y., Scapin, G., Palte, R.L. | 3.68 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1w72 | H | L | 0 | A | C | protein | peptide | NA | NA | hla class i histocompatibility antigen | melanoma-associated antigen 1 | IMMUNE SYSTEM | 08/27/04 | Crystal structure of HLA-A1:MAGE-A1 in complex with Fab-Hyb3 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Hulsmeyer, M., Chames, P., Hillig, R.C., Stanfield, R.L., Held, G., Coulie, P.G., Alings, C., Wille, G., Saenger, W., Ziegler, B.Uchanska-, Hoogenboom, H.R., Zieger, A. | 2.15 | X-RAY DIFFRACTION | 0.248 | 0.182 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -10.71 | SPR | null | 15537658 |
7lf0 | G | I | 0 | A | protein | null | arginase-1 | HYDROLASE/IMMUNE SYSTEM | 01/15/21 | Trimeric human Arginase 1 in complex with mAb2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gomez-Llorente, Y., Scapin, G., Palte, R.L. | 3.68 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7mjl | H | L | 0 | A | protein | null | spike glycoprotein | Viral Protein/Immune System | 04/20/21 | Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (focused refinement of RBD and Fab ab1) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SYNTHETIC CONSTRUCT | synthetic construct | synthetic construct | severe acute respiratory syndrome coronavirus2 | Zhu, X., Mannar, D., Srivastava, S.S., Berezuk, A.M., Demers, J.P., Saville, J.W., Leopold, K., Li, W., Dimitrov, D.S., Tuttle, K.S., Zhou, S., Chittori, S., Subramaniam, S. | 2.95 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7ezh | H | h | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 06/01/21 | Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gi complex | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | homo sapiens | Liu, Q.F., Yang, D.H., Zhuang, Y.W., Croll, T.I., Cai, X.Q., Duan, J., Dai, A.T., Yin, W.C., Ye, C.Y., Zhou, F.L., Wu, B.L., Zhao, Q., Xu, H.E., Wang, M.W., Jiang, Y. | 3.2 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
2kh2 | B | b | 60 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
1oar | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/21/03 | Fv IgE SPE-7 in complex with Alizarin Red | RATTUS RATTUS | rattus rattus | rattus rattus | null | James, L.C., Roversi, P., Tawfik, D. | 2.23 | X-RAY DIFFRACTION | 0.241 | 0.205 | false | true | IGHV1 | IGLV1 | Lambda | 0 | null | Other | 20 | 12610298 |
7l6v | B | null | 0 | A | protein | null | bont/a | ANTITOXIN | 12/24/20 | Crystal structure of BoNT/A-LC-JPU-A5-JPU-C1-JPU-H7-JPU-D12-ciA-F12 | CLOSTRIDIUM BOTULINUM; VICUGNA PACOS | vicugna pacos | null | clostridium botulinum | Lam, K., Jin, R. | 2.01 | X-RAY DIFFRACTION | 0.234 | 0.197 | false | true | IGHV1 | null | null | null | null | null | null | null |
4grw | G | null | 0 | B | protein | null | interleukin-12 subunit beta | IMMUNE SYSTEM | 08/27/12 | Structure of a complex of human IL-23 with 3 Nanobodies (Llama vHHs) | LLAMA GLAMA; HOMO SAPIENS; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | Desmyter, A., Spinelli, S., Button, C., Saunders, M., de Haard, H., Rommelaere, H., Union, A., Cambillau, C. | 2.55 | X-RAY DIFFRACTION | 0.218 | 0.183 | false | true | IGHV1 | null | null | null | null | null | null | null |
1c5c | H | L | 0 | L | Hapten | TK4 | 2-ACETYLAMINO-NAPTHALENE-1,5-DISULFONIC ACID | IMMUNE SYSTEM | 11/09/99 | DECARBOXYLASE CATALYTIC ANTIBODY 21D8-HAPTEN COMPLEX | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | mus musculus, homo sapiens | Hotta, K., Wilson, I.A. | 1.61 | X-RAY DIFFRACTION | unknown | unknown | false | true | IGHV1 | IGKV9 | Kappa | 0 | -9.493239 | Unknown | null | TBD |
2kqn | null | A | 16 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the AL-09 H87Y immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
6rbb | H | null | 0 | null | null | null | null | IMMUNE SYSTEM | 05/13/20 | CRYSTAL STRUCTURE OF the VhH-domain of anti-IL-17A antibody netakimab | LAMA GLAMA | lama glama | null | null | Kostareva, O.S., Kolyadenko, I.A., Ulitin, A.B., Ekimova, V.M., Evdokimov, S.R., Garber, M.B., Tishchenko, T.V., Gabdulkhakov, A.G. | 2.45 | X-RAY DIFFRACTION | 0.280 | 0.216 | false | true | IGHV1 | null | null | null | null | null | null | null |
4b5e | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 08/03/12 | Crystal Structure of an amyloid-beta binding single chain antibody PS2-8 | LAMA GLAMA | lama glama | null | null | Beringer, D.X., Dorresteijn, B., Rutten, L., Wienk, H., el Khattabi, M., Kroon-Batenburg, L.M.J., Verrips, C.T. | 1.936 | X-RAY DIFFRACTION | 0.2356 | 0.1812 | false | true | IGHV1 | null | null | null | null | null | null | null |
7rxc | N | null | 0 | K | protein | null | er lumen protein-retaining receptor 2 | STRUCTURAL PROTEIN | 08/22/21 | CryoEM structure of KDELR with Legobody | MUS MUSCULUS; VICUGNA PACOS; ESCHERICHIA COLI; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS SP.; GALLUS GALLUS | vicugna pacos | null | gallus gallus | Wu, X.D., Rapoport, T.A. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
1sjx | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 03/04/04 | Three-Dimensional Structure of a Llama VHH Domain OE7 binding the cell wall protein Malf1 | LAMA GLAMA | lama glama | null | null | Dolk, E., van der Vaart, M., Hulsik, D.L., Vriend, G., de Haard, H., Spinelli, S., Cambillau, C., Frenken, L., Verrips, T. | 2.2 | X-RAY DIFFRACTION | 0.206 | 0.191 | false | true | IGHV1 | null | null | null | null | null | null | null |
4w2p | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 08/17/17 | Anti-Marburgvirus Nucleoprotein Single Domain Antibody C | LAMA GLAMA | lama glama | null | null | Taylor, A.B., Garza, J.A. | 1.77 | X-RAY DIFFRACTION | 0.203 | 0.165 | false | true | IGHV1 | null | null | null | null | null | null | null |
6rtw | B | null | 0 | A | protein | null | protein patched homolog 1 | MEMBRANE PROTEIN | 05/27/19 | Crystal structure of the Patched-1 (PTCH1) ectodomain in complex with nanobody NB64 and cholesterol-hemisuccinate | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Rudolf, A.F., Kowatsch, C., El Omari, K., Malinauskas, T., Kinnebrew, M., Ansell, T.B., Bishop, B., Pardon, E., Schwab, R.A., Qian, M., Duman, R., Covey, D.F., Steyaert, J., Wagner, A., Sansom, M.S.P., Rohatgi, R., Siebold, C. | 1.9 | X-RAY DIFFRACTION | 0.230 | 0.185 | false | true | IGHV1 | null | null | null | null | null | null | null |
5wcc | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/29/17 | Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 02-1F07 Fab. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Joyce, M.G., Andrews, S.F., Mascola, J.R., McDermott, A.B., Kwong, P.D. | 2.461 | X-RAY DIFFRACTION | 0.240 | 0.203 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
6ru3 | C | null | 0 | null | null | null | null | IMMUNE SYSTEM | 05/27/19 | Crystal structure of the FP specific nanobody hFPNb1 | LAMA GLAMA | lama glama | null | null | Mazarakis, S.M.M., Pedersen, D.V., Laursen, N.S., Andersen, G.R. | 1.26 | X-RAY DIFFRACTION | 0.204 | 0.188 | false | true | IGHV1 | null | null | null | null | null | null | null |
5kel | J | N | 0 | E | protein | null | ebola surface glycoprotein, gp1 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/09/16 | EBOV GP in complex with variable Fab domains of IgGs c2G4 and c13C6 | ZAIRE EBOLAVIRUS; HOMO SAPIENS; ZAIRE EBOLAVIRUS (STRAIN MAYINGA-76) | homo sapiens | homo sapiens | zaire ebolavirus (strain mayinga-76) | Pallesen, J., Murin, C.D., de Val, N., Cottrell, C.A., Hastie, K.M., Turner, H.L., Fusco, M.L., Flyak, A.I., Zeitlin, L., Crowe Jr., J.E., Andersen, K.G., Saphire, E.O., Ward, A.B. | 4.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV8 | IGKV6 | Kappa | null | null | null | null | null |
6dwi | L | K | 0 | L | carbohydrate | HD4 | 4-O-[2-acetamido-2-deoxy-beta-D-glucopyranosyl]-1-O-phosphono-D-ribitol | IMMUNE SYSTEM | 06/26/18 | Structure of the 4462 Antibody Fab fragment bound to a Staphylococcus aureus wall techoic acid analog | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Fong, R., Lupardus, P.J. | 2.39 | X-RAY DIFFRACTION | 0.249 | 0.203 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6um7 | F | G | 0 | E | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/immune system | 10/09/19 | Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.mu1 in complex with CH848 10.17DT Env | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Henderson, R.C., Saunders, K., Haynes, B.F. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
7m71 | H | L | 0 | A | B | protein | protein | NA | NA | spike glycoprotein | spike glycoprotein | VIRAL PROTEIN | 03/26/21 | SARS-CoV-2 Spike:5A6 Fab complex I focused refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | severe acute respiratory syndrome coronavirus2 | Asarnow, D., Cheng, Y. | 2.66 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6wn1 | B | C | 0 | A | protein | null | reticulocyte binding protein 2b | CELL INVASION | 04/22/20 | Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 241242 | PLASMODIUM VIVAX SAL-1; HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium vivax sal-1 | Chan, L.J., Dietrich, M.H., Tham, W.H. | 3.15 | X-RAY DIFFRACTION | 0.283 | 0.251 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
3wfb | H | L | 0 | B | C | protein | protein | NA | NA | nitric oxide reductase subunit b | nitric oxide reductase subunit c | IMMUNE SYSTEM/OXIDOREDUCTASE | 07/18/13 | Reduced cytochrome c-dependent nitric oxide reductase (cNOR) from Pseudomonas aeruginosa in complex with antibody fragment | PSEUDOMONAS AERUGINOSA; MUS MUSCULUS | mus musculus | mus musculus | pseudomonas aeruginosa | pseudomonas aeruginosa | Sato, N., Ishii, S., Hino, T., Sugimoto, H., Fukumori, Y., Shiro, Y., Tosha, T. | 2.7 | X-RAY DIFFRACTION | 0.250 | 0.202 | false | false | IGHV1 | IGKV16 | Kappa | null | null | null | null | null |
4tuj | A | B | 0 | E | peptide | null | peptide1 | IMMUNE SYSTEM | 06/24/14 | Crystal structure of monoclonal antibody against neuroblastoma associated antigen. | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Grudnik, P., Golik, P., Horwacik, I., Zdzalik, M., Rokita, H., Dubin, G. | 1.89 | X-RAY DIFFRACTION | 0.232 | 0.179 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3b2v | H | L | 0 | A | protein | null | epidermal growth factor receptor | IMMUNE SYSTEM/TRANSFERASE | 10/19/07 | Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ferguson, K.M., Li, S., Kussie, P. | 3.3 | X-RAY DIFFRACTION | 0.367 | 0.282 | false | true | IGHV4 | IGKV3 | Kappa | 0 | -11.56 | SPR | 25 | 18275813 |
5lqb | H | L | 0 | A | protein | null | interleukin-2 | CYTOKINE | 08/16/16 | Complex structure of human IL2 mutant, Proleukin, with Fab fragment of NARA1 antibody | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Zou, C., Wirth, E. | 1.95 | X-RAY DIFFRACTION | 0.291 | 0.189 | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4dgy | H | L | 0 | A | peptide | null | e2 peptide | IMMUNE SYSTEM/VIRAL PROTEIN | 01/27/12 | Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody HCV1, C2 form | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | hepatitis c virus | Kong, L., Wilson, I.A., Law, M. | 1.798 | X-RAY DIFFRACTION | 0.221 | 0.188 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
1jnl | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/24/01 | Crystal Structure of Fab-Estradiol Complexes | MUS MUSCULUS | mus musculus | mus musculus | null | Monnet, C., Bettsworth, F., Stura, E.A., Le Du, M.-H., Menez, R., Derrien, L., Zinn-Justin, S., Gilquin, B., Sibai, G., Battail-Poirot, N., Jolivet, M., Menez, A., Arnaud, M., Ducancel, F., Charbonnier, J.B. | 3.0 | X-RAY DIFFRACTION | 0.290 | 0.195 | false | false | IGHV14 | IGKV12 | Kappa | null | null | null | null | null |
6njl | L | l | 0 | A | protein | null | glutamate receptor 1 | MEMBRANE PROTEIN/IMMUNE SYSTEM | 01/03/19 | structure of a complex | MUS MUSCULUS; RATTUS NORVEGICUS | mus musculus | null | rattus norvegicus | Gouaux, E., Zhao, Y. | 6.7 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7k8x | D | F | 0 | B | C | protein | protein | NA | NA | spike glycoprotein | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 09/27/20 | Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | severe acute respiratory syndrome coronavirus2 | Abernathy, M.E., Barnes, C.O., Bjorkman, P.J. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
7qny | A | B | 0 | E | protein | null | surface glycoprotein | VIRAL PROTEIN | 12/23/21 | The receptor binding domain of SARS-CoV-2 spike glycoprotein in complex with COVOX-58 and COVOX-158 Fabs | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 2.84 | X-RAY DIFFRACTION | 0.278 | 0.226 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
7s6l | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 09/14/21 | J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (conformation 3) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Ozorowski, G., Torres, J.L., Ward, A.B. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5fcs | L | l | 0 | null | null | null | null | IMMUNE SYSTEM | 12/15/15 | Diabody | HOMO SAPIENS | homo sapiens | null | null | Mosyak, L., Root, A. | 2.01 | X-RAY DIFFRACTION | 0.205 | 0.176 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6oel | H | L | 0 | B | C | protein | protein | NA | NA | interleukin-4 receptor subunit alpha | cytokine receptor common subunit gamma | IMMUNE SYSTEM | 03/27/19 | Engineered Fab bound to IL-4 receptor | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Jude, K.M., Moraga, I., Spangler, J.B., Garcia, K.C. | 3.1 | X-RAY DIFFRACTION | 0.256 | 0.199 | false | true | IGHV6 | IGKV1 | Kappa | null | null | null | null | null |
2exy | C | D | 0 | A | protein | null | h(+)/cl(-) exchange transporter clca | MEMBRANE PROTEIN | 11/09/05 | Crystal structure of the E148Q Mutant of EcClC, Fab complexed in absence of bound ions | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Lobet, S., Dutzler, R. | 3.1 | X-RAY DIFFRACTION | 0.352 | 0.328 | false | false | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
5gs2 | H | h | 0 | A | protein | null | maltose-binding periplasmic protein | SUGAR BINDING PROTEIN/IMMUNE SYSTEM | 08/13/16 | Crystal structure of diabody complex with repebody and MBP | MUS MUSCULUS; HOMO SAPIENS; ESCHERICHIA COLI (STRAIN K12); ESCHERICHIA COLI | homo sapiens | null | escherichia coli (strain k12) | Kim, J.H., Song, D.H., Youn, S.J., Kim, J.W., Cho, G., Lee, H., Lee, J.O. | 3.592 | X-RAY DIFFRACTION | 0.278 | 0.217 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6nmu | H | L | 0 | S | protein | null | tyrosine-protein phosphatase non-receptor type substrate 1 | IMMUNE SYSTEM | 01/11/19 | Kick-Off Fab 115 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wibowo, A.S., Carter, J.J., Sim, J. | 2.55 | X-RAY DIFFRACTION | 0.261 | 0.193 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
3v6z | C | D | 0 | E | protein | null | e-antigen | IMMUNE SYSTEM | 12/20/11 | Crystal Structure of Hepatitis B Virus e-antigen | HEPATITIS B VIRUS; MUS MUSCULUS | mus musculus | mus musculus | hepatitis b virus | Dimattia, M.A., Watts, N.R., Stahl, S.J., Grimes, J.M., Steven, A.C., Stuart, D.I., Wingfield, P.T. | 3.34 | X-RAY DIFFRACTION | 0.233 | 0.234 | false | false | IGHV5 | IGKV8 | Kappa | 0 | -11.570817 | SPR | null | TBD |
7ahu | H | L | 0 | C | D | protein | protein | NA | NA | coagulation factor x | coagulation factor x | BLOOD CLOTTING | 09/25/20 | Anti-FX Fab of mim8 in complex with human FXa | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Johansson, E. | 2.6 | X-RAY DIFFRACTION | 0.263 | 0.203 | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
6x87 | G | H | 0 | X | protein | null | circumsporozoite protein | IMMUNE SYSTEM | 06/01/20 | CryoEM structure of the Plasmodium berghei circumsporozoite protein in complex with inhibitory mouse antibody 3D11. | MUS MUSCULUS; PLASMODIUM BERGHEI | mus musculus | mus musculus | plasmodium berghei | Kucharska, I., Thai, E., Rubinstein, J., Julien, J.P. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7ejk | H | h | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(o) subunit alpha | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 04/02/21 | Structure of the alpha2A-adrenergic receptor GoA signaling complex bound to oxymetazoline | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | homo sapiens | Xu, J., Cao, S., Liu, Z., Du, Y. | 3.4 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
4yhz | H | L | 0 | P | peptide | null | h3k4me3 peptide | IMMUNE SYSTEM | 02/27/15 | Crystal structure of 304M3-B Fab in complex with H3K4me3 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | synthetic construct | Hattori, T., Dementieva, I.S., Montano, S.P., Koide, S. | 2.304 | X-RAY DIFFRACTION | 0.213 | 0.183 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -10.857483 | Unknown | null | TBD |
5o0w | E | null | 0 | A | protein | null | fructose-bisphosphate aldolase | LYASE | 05/17/17 | Crystal structure of the complex between Nb474 and Trypanosoma congolense fructose-1,6-bisphosphate aldolase | TRYPANOSOMA CONGOLENSE (STRAIN IL3000); VICUGNA PACOS | vicugna pacos | null | trypanosoma congolense (strain il3000) | Pinto, J., Magez, S., Sterckx, Y. | 2.57 | X-RAY DIFFRACTION | 0.222 | 0.192 | false | true | IGHV1 | null | null | 0 | -13.822203 | SPR | null | TBD |
5b4m | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 04/05/16 | Crystal structure of an Fab against human influenza A | MUS MUSCULUS | mus musculus | mus musculus | null | Yuan, Y.A. | 2.4 | X-RAY DIFFRACTION | 0.338 | 0.285 | false | false | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
6xpq | B | C | 0 | A | protein | null | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 07/08/20 | Human antibody D1 H1-17/H3-14 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2) | INFLUENZA A VIRUS (A/TEXAS/50/2012(H3N2)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/texas/50/2012(h3n2)) | McCarthy, K.R., Harrison, S.C. | 4.2 | X-RAY DIFFRACTION | 0.307 | 0.273 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
3wii | I | M | 0 | null | null | null | null | IMMUNE SYSTEM | 09/12/13 | Crystal structure of the Fab fragment of B2212A, a murine monoclonal antibody specific for the third fibronectin domain (Fn3) of human ROBO1. | MUS MUSCULUS | mus musculus | mus musculus | null | Nakayama, T., Mizohata, E., Yamashita, T., Nagatoishi, S., Nakakido, M., Iwanari, H., Mochizuki, Y., Kado, Y., Yokota, Y., Sato, R., Tsumoto, K., Fujitani, H., Kodama, T., Hamakubo, T., Inoue, T. | 1.6 | X-RAY DIFFRACTION | 0.230 | 0.185 | false | false | IGHV1 | IGKV10 | Kappa | null | null | null | null | null |
6xuk | H | L | 0 | A | carbohydrate | NAG | N-ACETYL-D-GLUCOSAMINE | ANTITUMOR PROTEIN | 01/20/20 | AbLIFT design 15 of Ab 1116NS19.9 | MUS MUSCULUS | mus musculus | mus musculus | null | Diskin, R., Borenstein-Katz, A. | 1.42 | X-RAY DIFFRACTION | 0.185 | 0.149 | false | true | IGHV6 | IGKV14 | Kappa | null | null | null | null | null |
3v6f | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 12/19/11 | Crystal Structure of an anti-HBV e-antigen monoclonal Fab fragment (e6), unbound | MUS MUSCULUS | mus musculus | mus musculus | null | Dimattia, M.A., Watts, N.R., Stahl, S.J., Grimes, J.M., Steven, A.C., Stuart, D.I., Wingfield, P.T. | 2.52 | X-RAY DIFFRACTION | 0.220 | 0.179 | false | false | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
7f07 | C | null | 0 | null | null | null | null | RNA BINDING PROTEIN | 06/03/21 | Autonomous VH domain that interacts with eIF4E at the Capped mRNA Binding site. | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | null | Brown, C.J., Frosi, Y., Ng, S., Lin, Y.C. | 2.25 | X-RAY DIFFRACTION | 0.266 | 0.215 | false | true | IGHV3 | null | null | null | null | null | null | null |
6cyf | U | T | 0 | Q | protein | null | type iii secretion system protein | IMMUNE SYSTEM | 04/05/18 | PcrV fragment with bound Fab | PSEUDOMONAS AERUGINOSA; HOMO SAPIENS | homo sapiens | homo sapiens | pseudomonas aeruginosa | Oganesyan, V. | 2.78 | X-RAY DIFFRACTION | 0.249 | 0.215 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3gjf | M | K | 0 | D | F | protein | peptide | NA | NA | hla class i histocompatibility antigen, a-2alpha chain | nyeso-1 peptide | IMMUNE SYSTEM | 03/08/09 | Rational development of high-affinity T-cell receptor-like antibodies | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | | Stewart-Jones, G., Wadle, A., Hombach, A., Shenderov, E., Held, G., Fischer, E., Kleber, S., Stenner-Liewen, F., Bauer, S., McMichael, A., Knuth, A., Abken, H., Hombach, A.A., Cerundolo, V., Jones, E.Y., Renner, C. | 1.9 | X-RAY DIFFRACTION | 0.251 | 0.202 | false | true | IGHV3 | IGLV2 | Lambda | 0 | -9.82 | SPR | null | 19307587 |
6qd6 | J | null | 0 | null | null | null | null | STRUCTURAL PROTEIN | 12/31/18 | Molecular scaffolds expand the nanobody toolkit for cryo-EM applications: crystal structure of Mb-cHopQ-Nb207 | HELICOBACTER PYLORI; HELICOBACTER PYLORI (STRAIN G27) | helicobacter pylori, helicobacter pylori(strain g27) | null | null | Uchanski, T., Masiulis, S., Fischer, B., Kalichuk, V., Wohlkonig, A., Zogg, T., Remaut, H., Vranken, W., Aricescu, A.R., Pardon, E., Steyaert, J. | 2.84 | X-RAY DIFFRACTION | 0.239 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
7ns6 | G | null | 0 | L | protein | null | spike glycoprotein,fibritin | VIRAL PROTEIN | 03/05/21 | SARS-CoV-2 Spike (dimers) in complex with six Fu2 nanobodies | VICUGNA PACOS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; ENTEROBACTERIA PHAGE T4 | vicugna pacos | null | severe acute respiratory syndrome coronavirus2, enterobacteria phage t4 | Das, H., Hallberg, B.M. | 3.18 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
2kh2 | B | b | 53 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7r8n | O | P | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/26/21 | Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C051 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Barnes, C.O., Bjorkman, P.J. | 3.55 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
5vm4 | B | null | 0 | null | null | null | null | UNKNOWN FUNCTION | 04/26/17 | The apo form of the triclocarban-binding single domain camelid nanobody VHH T10 | LAMA GLAMA | lama glama | null | null | Tabares-da Rosa, S., Gonzalez-Sapienza, G., Wilson, D.K. | 1.9 | X-RAY DIFFRACTION | 0.241 | 0.197 | false | true | unknown | unknown | unknown | null | null | null | null | null |
6rco | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 04/11/19 | PfRH5-binding monoclonal antibody R5.004 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Alanine, D.G.W., Draper, S.J., Higgins, M.K. | 1.66 | X-RAY DIFFRACTION | 0.204 | 0.183 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
2kqm | null | B | 14 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
4laj | I | null | 0 | B | C | protein | peptide | NA | NA | hiv-1 yu2 gp120 envelope glycoprotein | cd4-mimetic miniprotein m48u1 | VIRAL PROTEIN/INHIBITOR | 06/20/13 | Crystal structure of HIV-1 YU2 envelope gp120 glycoprotein in complex with CD4-mimetic miniprotein, M48U1, and llama single-domain, broadly neutralizing, co-receptor binding site antibody, JM4 | HUMAN IMMUNODEFICIENCY VIRUS 1; LLAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | human immunodeficiency virus 1 | | Acharya, P., Luongo, T.S., Kwong, P.D. | 2.14 | X-RAY DIFFRACTION | 0.227 | 0.185 | false | true | IGHV1 | null | null | null | null | null | null | null |
5ezl | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/26/15 | Crystal Structure of Fab c12 | MUS MUSCULUS | mus musculus | mus musculus | null | Favuzza, P., Pluschke, G., Rudolph, M.G. | 2.43 | X-RAY DIFFRACTION | 0.245 | 0.187 | false | true | IGHV4 | IGKV6 | Kappa | null | null | null | null | null |
5f1o | B | null | 0 | A | protein | null | adp-ribosyl cyclase/cyclic adp-ribose hydrolase 1 | HYDROLASE/IMMUNE SYSTEM | 11/30/15 | human CD38 in complex with nanobody MU551 | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | Zhang, H., Hao, Q. | 2.2 | X-RAY DIFFRACTION | 0.237 | 0.168 | false | true | IGHV1 | null | null | null | null | null | null | null |
3k81 | A | null | 0 | D | protein | null | mp18 rna editing complex protein | Immune System, RNA Binding Protein | 10/13/09 | Structure of the central interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies | TRYPANOSOMA BRUCEI; LAMA GLAMA | lama glama | null | trypanosoma brucei | Park, Y.-J., Hol, W. | 3.4 | X-RAY DIFFRACTION | 0.320 | 0.267 | false | true | IGHV1 | null | null | null | null | null | null | null |
2kh2 | B | b | 10 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
3w9d | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 04/03/13 | Structure of Human Monoclonal Antibody E317 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Lee, C.C., Lin, L.L., Wang, A.H.J. | 2.32 | X-RAY DIFFRACTION | 0.259 | 0.190 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7ew2 | S | s | 0 | A | C | B | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 05/24/21 | Cryo-EM structure of pFTY720-bound Sphingosine 1-phosphate receptor 3 in complex with Gi protein | HOMO SAPIENS | homo sapiens | null | homo sapiens | homo sapiens | homo sapiens | Zhao, C., Wang, W., Wang, H.L., Shao, Z.H. | 3.1 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
3chn | D | N | 0 | null | null | null | null | IMMUNE SYSTEM | 03/10/08 | Solution structure of human secretory IgA1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4cad | B | A | 0 | C | protein | null | ras and a-factor converting enzyme 1, rce1 | PROTEIN BINDING | 10/08/13 | Mechanism of farnesylated CAAX protein processing by the integral membrane protease Rce1 | METHANOCOCCUS MARIPALUDIS; MUS MUSCULUS | mus musculus | mus musculus | methanococcus maripaludis | Kulkarni, K., Manolaridis, I., Dodd, R.B., Cronin, N., Ogasawara, S., Iwata, S., Barford, D. | 2.5 | X-RAY DIFFRACTION | 0.2669 | 0.2262 | false | false | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
4lf3 | B | A | 0 | C | protein | null | glucagon receptor | IMMUNE SYSTEM | 06/26/13 | Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Murray, J.M., Mukund, S. | 2.735 | X-RAY DIFFRACTION | 0.264 | 0.209 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4krp | D | C | 0 | A | protein | null | epidermal growth factor receptor | TRANSFERASE/IMMUNE SYSTEM | 05/16/13 | Nanobody/VHH domain 9G8 in complex with the extracellular region of EGFR | HOMO SAPIENS; LAMA GLAMA; MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | homo sapiens | Ferguson, K.M., Schmitz, K.R. | 2.823 | X-RAY DIFFRACTION | 0.263 | 0.215 | false | true | IGHV2 | IGKV5 | Kappa | 0 | -9.249427 | SPR | null | TBD |
7kx4 | D | A | 0 | null | null | null | null | IMMUNE SYSTEM | 12/03/20 | Anti-CCHFV ADI-36121 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Mishra, A.K., McLellan, J.S. | 2.6 | X-RAY DIFFRACTION | 0.239 | 0.198 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6vkn | G | J | 0 | C | F | protein | protein | NA | NA | envelope glycoprotein gp160 | bg505 sosipv5.2 gp41 | VIRAL PROTEIN/Immune System | 01/21/20 | BG505 SOSIP.v5.2.N241.N289 in complex with rhesus macaque Fab RM19R | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Cottrell, C.A., Ward, A.B. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
4ocl | C | null | 0 | B | A | protein | protein | NA | NA | 26s proteasome regulatory subunit rpn11 | 26s proteasome regulatory subunit rpn8 | HYDROLASE, PROTEIN BINDING | 01/09/14 | Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ia | SACCHAROMYCES CEREVISIAE; LAMA GLAMA | lama glama | null | saccharomyces cerevisiae | saccharomyces cerevisiae | Pathare, G.R., Bracher, A. | 2.4 | X-RAY DIFFRACTION | 0.252 | 0.195 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ss6 | J | N | 0 | C | protein | null | unknown | PROTEIN BINDING | 09/06/19 | Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0020187 | HOMO SAPIENS | null | null | null | Burschowsky, D., Addyman, A., Fiedler, S., Groves, M., Haynes, S., Seewooruthun, C., Carr, M. | 3.25 | X-RAY DIFFRACTION | 0.361 | 0.300 | false | false | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
6x1a | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 05/18/20 | Non peptide agonist PF-06882961, bound to Glucagon-Like peptide-1 (GLP-1) Receptor | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | homo sapiens | Belousoff, M.J., Zhang, X., Danev, R. | 2.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
1mco | H | L | 0 | null | null | null | null | IMMUNOGLOBULIN | 02/25/93 | THREE-DIMENSIONAL STRUCTURE OF A HUMAN IMMUNOGLOBULIN WITH A HINGE DELETION | HOMO SAPIENS | homo sapiens | homo sapiens | null | Guddat, L.W., Edmundson, A.B. | 3.2 | X-RAY DIFFRACTION | unknown | 0.232 | false | false | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
6ad7 | E | F | 0 | B | protein | null | h(+)/cl(-) exchange transporter clca | TRANSPORT PROTEIN | 07/31/18 | Crystal structure of the E148D mutant CLC-ec1 in 20 mM bromide | ESCHERICHIA COLI (STRAIN K12); MUS MUSCULUS | mus musculus | mus musculus | escherichia coli (strain k12) | Lim, H.-H., Park, K. | 2.95 | X-RAY DIFFRACTION | 0.269 | 0.223 | false | false | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
5l6q | null | A | 0 | null | null | null | null | IMMUNE SYSTEM | 05/31/16 | Refolded AL protein from cardiac amyloidosis | HOMO SAPIENS | null | homo sapiens | null | Annamalai, K., Liberta, F., Vielberg, M.-T., Lilie, H., Guehrs, K.-H., Schierhorn, A., Koehler, R., Schmidt, A., Haupt, C., Hegenbart, O., Schoenland, S., Groll, M., Faendrich, M. | 1.4 | X-RAY DIFFRACTION | 0.182 | 0.147 | false | false | null | IGLV3 | Lambda | null | null | null | null | null |
7ly2 | M | K | 0 | J | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 03/05/21 | SARS-CoV-2 S/S2M11/S2M28 Global Refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 2.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5w08 | G | H | 0 | A | protein | null | hemagglutinin ha1 | VIRAL PROTEIN/IMMUNE SYSTEM | 05/30/17 | A/Texas/50/2012(H3N2) Influenza hemagglutinin in complex with K03.12 Fab | INFLUENZA A VIRUS (A/TEXAS/50/2012(H3N2)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/texas/50/2012(h3n2)) | McCarthy, K.R., Harrison, S.C. | 2.6 | X-RAY DIFFRACTION | 0.262 | 0.240 | false | true | IGHV1 | IGLV2 | Lambda | 0 | -10.092596 | SPR | null | TBD |
4n1e | null | H | 0 | L | protein | null | lysozyme c | Immune system/Hydrolase | 10/04/13 | Structural evidence for antigen receptor evolution | HOMO SAPIENS; GALLUS GALLUS | null | homo sapiens | gallus gallus | Langley, D.B., Rouet, R., Stock, D., Christ, D. | 2.23 | X-RAY DIFFRACTION | 0.265 | 0.223 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
4r4b | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 08/19/14 | Crystal structure of the anti-hiv-1 antibody 2.2c | HOMO SAPIENS | homo sapiens | homo sapiens | null | McLellan, J.S., Acharya, P., Huang, C.-C., Robinson, J., Kwong, P.D. | 2.199 | X-RAY DIFFRACTION | 0.214 | 0.166 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6n4y | G | null | 0 | D | protein | null | metabotropic glutamate receptor 5 | MEMBRANE PROTEIN | 11/20/18 | Metabotropic Glutamate Receptor 5 Extracellular Domain with Nb43 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Koehl, A., Hu, H., Feng, D., Sun, B., Chu, M., Weis, W.I., Mathiesen, J.M., Skiniotis, G., Kobilka, B.K. | 3.262 | X-RAY DIFFRACTION | 0.251 | 0.199 | false | true | IGHV1 | null | null | null | null | null | null | null |
7uem | D | C | 0 | B | carbohydrate | GAL | BETA-D-GALACTOSE | IMMUNE SYSTEM | 03/22/22 | Genomic and structural basis for the human anti-alpha-galactosyl antibody response | Homo sapiens | homo sapiens | homo sapiens | null | Langley, D.B., Christ, D. | 2.314 | X-RAY DIFFRACTION | 0.231 | 0.189 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
2x1p | C | null | 0 | null | null | null | null | CONTRACTILE PROTEIN | 01/03/10 | Gelsolin Nanobody | LAMA GLAMA | lama glama | null | null | VandenAbbeele, A., DeClercq, S., DeGanck, A., DeCorte, V., VanLoo, B., Srinivasan, V., Steyaert, J., Vandekerckhove, J., Gettemans, J. | 1.1 | X-RAY DIFFRACTION | 0.220 | 0.203 | false | true | IGHV1 | null | null | null | null | null | null | null |
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