pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7cws | G | F | 0 | R | protein | null | spike glycoprotein | VIRAL PROTEIN | 08/31/20 | SARS-CoV-2 Spike Proteins Trimer in Complex with FC05 and H014 Fabs Cocktail | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, L., Wang, X. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
4o51 | D | C | 0 | O | peptide | null | ides hinge peptide | IMMUNE SYSTEM | 12/19/13 | Crystal structure of the QAA variant of anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide | ORYCTOLAGUS CUNICULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT | oryctolagus cuniculus, homo sapiens | oryctolagus cuniculus, homo sapiens | homo sapiens | Malia, T.J., Luo, J., Teplyakov, A., Gilliland, G.L. | 2.204 | X-RAY DIFFRACTION | 0.213 | 0.182 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6gkd | M | null | 0 | L | protein | null | cystic fibrosis transmembrane conductance regulator | HYDROLASE | 05/18/18 | human NBD1 of CFTR in complex with nanobodies D12 and G3a | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C. | 2.99 | X-RAY DIFFRACTION | 0.235 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
7akj | E | D | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 10/01/20 | Structure of the SARS-CoV spike glycoprotein in complex with the 47D11 neutralizing antibody Fab fragment | SARS CORONAVIRUS WH20; HOMO SAPIENS | homo sapiens | homo sapiens | sars coronavirus wh20 | Fedry, J., Hurdiss, D.L., Wang, C., Li, W., Obal, G., Drulyte, I., Howes, S.C., van Kuppeveld, F.J.M., Foerster, F., Bosch, B.J. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
7jwp | I | J | 0 | U | peptide | null | il-18 peptide | IMMUNE SYSTEM | 08/26/20 | Fab CJ11 in complex IL-18 peptide liberated by Caspase cleavage | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Payandeh, J., Ho, H. | 3.0 | X-RAY DIFFRACTION | 0.260 | 0.235 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7c4s | H | L | 0 | A | protein | null | sphingosine 1-phosphate receptor 3 | MEMBRANE PROTEIN | 05/18/20 | Sphingosine-1-phosphate receptor 3 with a natural ligand. | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Iwata, S., Maeda, S., Luo, F., Nango, E., hirata, K., Asada, H. | 3.2 | X-RAY DIFFRACTION | 0.263 | 0.242 | false | false | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
4cau | E | e | 0 | A | protein | null | envelope protein e | VIRUS | 10/09/13 | THREE-DIMENSIONAL STRUCTURE OF DENGUE VIRUS SEROTYPE 1 COMPLEXED WITH 2 HMAB 14C10 FAB | DENGUE VIRUS 1; HOMO SAPIENS | homo sapiens | null | dengue virus 1 | TEOH, E.P., KUKKARO, P., TEO, E.W., LIM, A.P., TAN, T.T., YIP, A., SCHUL, W., AUNG, M., KOSTYUCHENKO, V.A., LEO, Y.S., CHAN, S.H., SMITH, K.G., CHAN, A.H., ZOU, G., OOI, E.E., KEMENY, D.M., TAN, G.K., NG, J.K., NG, M.L., ALONSO, S., FISHER, D., SHI, P.Y., HANSON, B.J., LOK, S.M., MACARY, P.A. | 7.0 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
3jwd | H | L | 0 | A | protein | null | hiv-1 gp120 envelope glycoprotein | VIRAL PROTEIN | 09/18/09 | Structure of HIV-1 gp120 with gp41-Interactive Region: Layered Architecture and Basis of Conformational Mobility | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Pancera, M., Majeed, S., Ban, Y.A., Chen, L., Huang, C.C., Kong, L., Kwon, Y.D., Stuckey, J., Zhou, T., Robinson, J.E., Schief, W.R., Sodroski, J., Wyatt, R., Kwong, P.D. | 2.61 | X-RAY DIFFRACTION | 0.275 | 0.201 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4xxd | B | A | 0 | C | peptide | null | amyloid-beta fragment | IMMUNE SYSTEM | 01/30/15 | Crystal Structure of mid-region amyloid beta capture by solanezumab | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Hermans, S.J., Crespi, G.A.N., Parker, M.W., Miles, L.A. | 2.41 | X-RAY DIFFRACTION | 0.290 | 0.249 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
3zhd | A | null | 0 | null | null | null | null | null | 12/21/12 | The crystal structure of single domain antibody 8-4 scaffold. | HOMO SAPIENS | homo sapiens | null | null | Song, H.-N., Woo, E.-J., Lim, H.-K. | 1.962 | X-RAY DIFFRACTION | 0.2311 | 0.1779 | false | true | IGHV3 | null | null | null | null | null | null | null |
3nif | H | L | 0 | A | D | protein | protein | NA | NA | integrin alphaiib beta3 | integrin beta-3 | CELL ADHESION/BLOOD CLOTTING | 06/15/10 | The Closed Headpiece of Integrin IIb 3 and its Complex with an IIb 3 -Specific Antagonist That Does Not Induce Opening | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | homo sapiens | Zhu, J.H., Zhu, J.Q., Springer, T.A. | 2.4 | X-RAY DIFFRACTION | 0.216 | 0.176 | false | true | IGHV14 | IGKV14 | Kappa | null | null | null | null | null |
5n2k | H | G | 0 | null | null | null | null | IMMUNE SYSTEM | 02/07/17 | Structure of unbound Briakinumab FAb | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bloch, Y., Savvides, S.N. | 2.219 | X-RAY DIFFRACTION | 0.234 | 0.204 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
4uim | E | F | 0 | null | null | null | null | null | 03/30/15 | crystal structure of quinine-dependent Fab 314.3 | MUS MUSCULUS | mus musculus | mus musculus | null | Zhu, J., Zhu, J., Bougie, D.W., Aster, R.H., Springer, T.A. | 2.7 | X-RAY DIFFRACTION | 0.2596 | 0.2215 | false | false | IGHV1 | IGKV10 | Kappa | null | null | null | null | null |
7v26 | a | b | 0 | A | protein | null | xg005 heavy chain | VIRAL PROTEIN | 08/07/21 | XG005-bound SARS-CoV-2 S | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhan, W.Q., Zhang, X., Sun, L., Chen, Z.G. | 3.85 | ELECTRON MICROSCOPY | null | null | false | false | IGHV2 | IGLV2 | Lambda | null | null | null | null | null |
6mnq | H | L | 0 | P | peptide | null | envelope glycoprotein | IMMUNE SYSTEM | 10/02/18 | Rhesus macaque anti-HIV V3 antibody DH727.2 with gp120 V3 ZAM18 peptide | MACACA MULATTA; SYNTHETIC CONSTRUCT | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Nicely, N.I. | 1.804 | X-RAY DIFFRACTION | 0.225 | 0.185 | false | true | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
4jam | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/18/13 | Crystal structure of broadly neutralizing anti-hiv-1 antibody ch103 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Zhou, T., Moquin, S., Zheng, A., Srivatsan, S., Kwong, P.D. | 1.65 | X-RAY DIFFRACTION | 0.197 | 0.169 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
1iga | B | D | 0 | null | null | null | null | IMMUNOGLOBULIN | 12/23/98 | MODEL OF HUMAN IGA1 DETERMINED BY SOLUTION SCATTERING CURVE-FITTING AND HOMOLOGY MODELLING | HOMO SAPIENS | homo sapiens | homo sapiens | null | Boehm, M.K., Woof, J.M., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4hs6 | H | L | 0 | Y | peptide | null | e2-peptide | IMMUNE SYSTEM | 10/29/12 | Hepatitus C envelope glycoprotein E2 fragment 412-423 with humanized and affinity-matured antibody MRCT10.v362 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | hepatitis c virus | Eigenbrot, C., Ultsch, M. | 1.53 | X-RAY DIFFRACTION | 0.200 | 0.175 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -10.263043 | Unknown | null | TBD |
5dhy | A | B | 0 | C | protein | null | protein rev | IMMUNE SYSTEM | 08/31/15 | HIV-1 Rev NTD dimers with variable crossing angles | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | DiMattia, M.A., Watts, N.R., Wingfield, P.T., Grimes, J.M., Stuart, D.I., Steven, A.C. | 3.1 | X-RAY DIFFRACTION | 0.300 | 0.291 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5xqy | null | A | 0 | null | null | null | null | IMMUNE SYSTEM | 06/07/17 | Structure of monomeric mutant of REI immunoglobulin light chain variable domain crystallized at pH 8 | HOMO SAPIENS | null | homo sapiens | null | Mine, S., Nakamura, T., Uegaki, K., Hamada, D. | 2.9 | X-RAY DIFFRACTION | 0.285 | 0.231 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
3j30 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 01/28/13 | Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab CHK152 | MUS MUSCULUS | mus musculus | mus musculus | null | Sun, S., Xiang, Y., Rossmann, M.G. | 16 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4x4x | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 12/04/14 | Retrofitting antibodies with stabilizing mutations. Herceptin scFv mutant. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Langley, D.B., Roome, B., Christ, D. | 2.25 | X-RAY DIFFRACTION | 0.269 | 0.226 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5sv4 | A | null | 0 | null | null | null | null | TOXIN | 08/04/16 | Anti-Ricin A-chain Single Domain Antibody A3C8 | LAMA GLAMA | lama glama | null | null | Compton, J.R., Legler, P.M. | 2.7 | X-RAY DIFFRACTION | 0.246 | 0.198 | false | true | IGHV1 | null | null | null | null | null | null | null |
6pk8 | C | c | 0 | null | null | null | null | IMMUNE SYSTEM | 06/28/19 | Antibody scFv-M204 dimeric state | ORYCTOLAGUS CUNICULUS | oryctolagus cuniculus | null | null | Abskharon, R., Sawaya, M.R., Seidler, P.M., Cascio, D., Eisenberg, D.S. | 2.91 | X-RAY DIFFRACTION | 0.238 | 0.186 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7eh3 | A | null | 6 | null | null | null | null | IMMUNE SYSTEM | 03/28/21 | Structure of Nanobody Nb23 in solution using NMR spectroscopy | LAMA GLAMA | lama glama | null | null | Percipalle, M., Hunashal, Y., Esposito, G., Fogolari, F. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6t3j | F | G | 0 | J | protein | null | tumor necrosis factor receptor superfamily member 10b | APOPTOSIS | 10/11/19 | Dual Epitope Targeting by Anti-DR5 Antibodies | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Tauchert, M.J., Augustin, M., Krapp, S., Overdijk, M.B., Breij, E.C.W., Hibbert, R.G. | 3.05 | X-RAY DIFFRACTION | 0.282 | 0.251 | false | true | IGHV14 | IGKV3 | Kappa | null | null | null | null | null |
2a6d | B | A | 0 | P | peptide | null | dodecapeptide, rlliadppspre | IMMUNE SYSTEM | 07/02/05 | Crystal structure analysis of the anti-arsonate germline antibody 36-65 in complex with a phage display derived dodecapeptide RLLIADPPSPRE | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Sethi, D.K., Agarwal, A., Manivel, V., Rao, K.V., Salunke, D.M. | 2.9 | X-RAY DIFFRACTION | 0.264 | 0.230 | false | false | IGHV1 | IGKV10 | Kappa | 0 | -9.309477 | Unknown | null | TBD |
3zkx | B | null | 0 | A | protein | null | beta-secretase 2 | HYDROLASE | 01/25/13 | TERNARY BACE2 XAPERONE COMPLEX | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Kuglstatter, A., Banner, D.W., Benz, J., Bertschinger, J., Burger, D., Cuppuleri, S., Debulpaep, M., Gast, A., Grabulovski, D., Gsell, B., Hilpert, H., Huber, W., Kusznir, E., Laeremans, T., Matile, H., Rufer, A., Schlatter, D., Steyeart, J., Stihle, M., Thoma, R., Weber, M., Ruf, A. | 2.37 | X-RAY DIFFRACTION | 0.2085 | 0.1849 | false | true | IGHV3 | null | null | null | null | null | null | null |
2ntf | B | A | 0 | B | Hapten | OHM | 3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE | IMMUNE SYSTEM | 11/07/06 | Crystal Structure of a Quorum-Quenching Antibody in Complex with an N-Acyl-L-Homoserine Lactone Analog | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Debler, E.W., Wilson, I.A. | 3.18 | X-RAY DIFFRACTION | 0.265 | 0.210 | false | false | IGHV1 | IGLV1 | Lambda | 0 | -9.25 | Other | 37 | 17400249 |
5ijk | A | C | 0 | X | peptide | null | peptide pro-leu-gln-pro-glu-gln-pro-phe-pro | IMMUNE SYSTEM | 03/02/16 | Crystal structure of anti-gliadin 1002-1E03 Fab fragment in complex of peptide PLQPEQPFP | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | triticum aestivum | Chen, X., Zhao, Y., Harlos, K., Snir, O., Sollid, L.M. | 2.5 | X-RAY DIFFRACTION | 0.265 | 0.209 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
7e5s | L | D | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 02/20/21 | SARS-CoV-2 S trimer with four-antibody cocktail complex | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Sun, Y., Wang, L., Wang, N., Feng, R., Wang, X. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7x9e | C | D | 0 | F | peptide | null | spike peptide | IMMUNE SYSTEM/VIRAL PROTEIN | 03/15/22 | Crystal structure of the 76E1 Fab in complex with a SARS-CoV-2 spike peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Chen, X., Zhang, T., Ding, J., Sun, X., Sun, B. | 2.6 | X-RAY DIFFRACTION | 0.243 | 0.195 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
5e94 | B | A | 0 | G | protein | null | glucagon-like peptide 1 receptor | MEMBRANE PROTEIN | 10/14/15 | Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Soroka, V., Schluckebier, G., Reedtz-Runge, S. | 2.0 | X-RAY DIFFRACTION | 0.232 | 0.188 | false | true | IGHV3 | IGKV10 | Kappa | null | null | null | null | null |
7kkk | D | null | 0 | C | protein | null | sars-cov-2 spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/27/20 | SARS-CoV-2 Spike in complex with neutralizing nanobody Nb6 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SYNTHETIC CONSTRUCT | synthetic construct | null | severe acute respiratory syndrome coronavirus2 | Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., ... | 3.03 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6fy0 | H | L | 0 | P | peptide | null | cap45 v2 peptide | IMMUNE SYSTEM | 03/10/18 | Crystal structure of a V2-directed, RV144 vaccine-like antibody from HIV-1 infection, CAP228-16H, bound to a heterologous V2 peptide | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Wibmer, C.K., Fernandes, M., Vijayakumar, B., Dirr, H.W., Sayed, Y., Moore, P.L., Morris, L. | 2.57 | X-RAY DIFFRACTION | 0.250 | 0.210 | false | true | IGHV5 | IGLV3 | Lambda | null | null | null | null | null |
6ye3 | G | H | 0 | I | protein | null | interleukin-2 | PROTEIN BINDING | 03/23/20 | IL-2 in complex with a Fab fragment from UFKA-20 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Karakus, U., Mittl, P., Boyman, O. | 2.89 | X-RAY DIFFRACTION | 0.283 | 0.215 | false | true | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
4q6i | E | D | 0 | J | protein | null | t-cell surface glycoprotein cd4 | IMMUNE SYSTEM | 04/22/14 | Crystal structure of murine 2D5 Fab, a potent anti-CD4 HIV-1-neutralizing antibody in complex with CD4 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Boyington, J.C., Nabel, G.J., Mascola, J.R. | 3.65 | X-RAY DIFFRACTION | 0.257 | 0.226 | false | false | IGHV9 | IGKV3 | Kappa | null | null | null | null | null |
6cnr | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/08/18 | aducanumab apo Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Arndt, J.W. | 2.09 | X-RAY DIFFRACTION | 0.239 | 0.211 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5vl2 | A | null | 0 | A | Hapten | 9EG | N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea | UNKNOWN FUNCTION | 04/24/17 | The hapten triclocarban bound to the single domain camelid nanobody VHH T4 | LAMA GLAMA | lama glama | null | lama glama | Tabares-da Rosa, S., Gonzalez-Sapienza, G., Wilson, D.K. | 1.9 | X-RAY DIFFRACTION | 0.263 | 0.219 | false | true | IGHV1 | null | null | null | null | null | null | null |
2fgw | H | L | 0 | null | null | null | null | IMMUNOGLOBULIN | 01/16/94 | X-RAY STRUCTURES OF FRAGMENTS FROM BINDING AND NONBINDING VERSIONS OF A HUMANIZED ANTI-CD18 ANTIBODY: STRUCTURAL INDICATIONS OF THE KEY ROLE OF VH RESIDUES 59 TO 65 | HOMO SAPIENS | null | null | null | Eigenbrot, C., Kessler, J. | 3.0 | X-RAY DIFFRACTION | unknown | 0.176 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4w6w | B | null | 0 | A | protein | null | f18 fimbrial adhesin ac | CELL ADHESION | 08/21/14 | Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF6 | ESCHERICHIA COLI DH5[ALPHA]; LAMA GLAMA | lama glama | null | escherichia coli dh5[alpha] | Moonens, K., De Kerpel, M., Annelies, C., Cox, E., Pardon, E., Remaut, H., De Greve, H. | 2.51 | X-RAY DIFFRACTION | 0.254 | 0.197 | false | true | IGHV1 | null | null | 0 | -11.524222 | SPR | null | TBD |
4wem | B | null | 0 | A | protein | null | k88 fimbrial protein ac | STRUCTURAL PROTEIN | 09/10/14 | Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V1 | ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | escherichia coli | Moonens, K., Van den Broeck, I., Pardon, E., De Kerpel, M., Remaut, H., De Greve, H. | 1.55 | X-RAY DIFFRACTION | 0.193 | 0.169 | false | true | IGHV1 | null | null | 0.000007 | -7.049719 | SPR | null | TBD |
7n65 | K | L | 0 | I | protein | null | envelope glycoprotein gp41 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/07/21 | Complex structure of HIV superinfection Fab QA013.2 and BG505.SOSIP.664 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Mangala Prasad, V., Shipley, M.M., Overbaugh, J.M., Lee, K.K. | 4.15 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
7web | G | I | 0 | D | protein | null | spike glycoprotein | IMMUNE SYSTEM/VIRAL PROTEIN | 12/23/21 | SARS-CoV-2 Omicron variant spike protein with two XGv347 binding to two open state RBDs | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Wang, L. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5vzr | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 05/29/17 | Crystal Structure of MERS-CoV neutralizing antibody G4 Fab | MUS MUSCULUS | mus musculus | mus musculus | null | Wang, N., Wrapp, D., McLellan, J.S. | 1.57 | X-RAY DIFFRACTION | 0.215 | 0.182 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5vjo | C | D | 0 | F | protein | null | lysozyme isoform i (del-i) | HYDROLASE/IMMUNE SYSTEM | 04/19/17 | Complex between HyHEL10 Fab fragment heavy chain mutant I29F and Pekin duck egg lysozyme isoform I (DEL-I) | MUS MUSCULUS; ANAS PLATYRHYNCHOS | mus musculus | mus musculus | anas platyrhynchos | Langley, D.B., Christ, D. | 2.43 | X-RAY DIFFRACTION | 0.296 | 0.262 | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
4otx | I | M | 0 | null | null | null | null | immune system | 02/14/14 | Structure of the anti-Francisella tularensis O-antigen antibody N203 Fab fragment | MUS MUSCULUS | mus musculus | mus musculus | null | Lu, Z., Rynkiewicz, M.J., Yang, C.-Y., Madico, G., Perkins, H.M., Roche, M.I., Seaton, B.A., Sharon, J. | 2.1 | X-RAY DIFFRACTION | 0.228 | 0.193 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7wd9 | G | H | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 12/21/21 | SARS-CoV-2 Beta spike in complex with three S3H3 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Wang, Y.F., Cong, Y. | 3.7 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6bt3 | H | G | 0 | K | J | protein | protein | NA | NA | major capsid protein l1 | major capsid protein l1 | VIRUS | 12/05/17 | High-Resolution Structure Analysis of Antibody V5 Conformational Epitope on Human Papillomavirus 16 | MUS MUSCULUS; HUMAN PAPILLOMAVIRUS TYPE 16 | mus musculus | mus musculus | human papillomavirus type 16 | human papillomavirus type 16 | Guan, J., Bywaters, S.M., Brendle, S.A., Ashley, R.E., Makhov, A.M., Conway, J.F., Christensen, N.D., Hafenstein, S. | 4.7 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
1ehl | H | L | 0 | A | nucleic-acid | null | 5'-(d(5ht)p*(6-4)t)-3' | IMMUNE SYSTEM | 02/21/00 | 64M-2 ANTIBODY FAB COMPLEXED WITH D(5HT)(6-4)T | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Yokoyama, H., Mizutani, R., Satow, Y., Komatsu, Y., Ohtsuka, E., Nikaido, O. | 2.4 | X-RAY DIFFRACTION | 0.279 | 0.192 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7zfd | A | B | 0 | F | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-25 Fab | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 3.39 | X-RAY DIFFRACTION | 0.338 | 0.286 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7kdd | F | G | 0 | B | protein | null | envelope glycoprotein b | VIRAL PROTEIN/IMMUNE SYSTEM | 10/08/20 | HCMV postfusion gB in complex with SM5-1 Fab | HOMO SAPIENS; HUMAN CYTOMEGALOVIRUS (STRAIN TOWNE) | homo sapiens | homo sapiens | human cytomegalovirus (strain towne) | Liu, Y., Heim, P.K., Che, Y., Chi, X., Qiu, X., Han, S., Dormitzer, P.R., Yang, X. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7lf1 | G | I | 0 | A | protein | null | arginase-1 | HYDROLASE/IMMUNE SYSTEM | 01/15/21 | Trimeric human Arginase 1 in complex with mAb3 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gomez-Llorente, Y., Scapin, G., Palte, R.L. | 4.04 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7mm0 | H | L | 0 | A | protein | null | spike glycoprotein | IMMUNE SYSTEM/VIRAL PROTEIN | 04/29/21 | Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, T., Tsybovsky, T., Kwong, P.D. | 3.15 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7sht | J | K | 0 | D | protein | null | immunoglobulin heavy constant epsilon | IMMUNE SYSTEM | 10/11/21 | Structure of a partially disrupted IgE high affinity receptor complex bound to an omalizumab variant | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Pennington, L.F., Jardetzky, T.S. | 7.29 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3chn | D | N | 8 | null | null | null | null | IMMUNE SYSTEM | 03/10/08 | Solution structure of human secretory IgA1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7swd | G | g | 0 | F | protein | null | virion spike glycoprotein | VIRAL PROTEIN/Immune System | 11/19/21 | Structure of EBOV GP lacking the mucin-like domain with 1C11 scFv and 1C3 Fab bound | ZAIRE EBOLAVIRUS (STRAIN GABON-94); ZAIRE EBOLAVIRUS; HOMO SAPIENS | homo sapiens | null | zaire ebolavirus | Milligan, J.C., Yu, X., Saphire, E.O. | 3.59 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7d3l | H | L | 0 | 2 | protein | null | o/tibet/99 vp2 | VIRUS | 09/19/20 | FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY F145 | BOS TAURUS; FOOT-AND-MOUTH DISEASE VIRUS | bos taurus | bos taurus | foot-and-mouth disease virus | He, Y., Lou, Z. | 3.68 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6psc | B | b | 0 | null | null | null | null | IMMUNE SYSTEM | 06/17/20 | Antibody scFv-M204 trimeric state | ORYCTOLAGUS CUNICULUS | oryctolagus cuniculus | null | null | Abskharon, R., Sawaya, M.R., Seidler, P.M., Cascio, D., Eisenberg, D.S. | 3.6 | X-RAY DIFFRACTION | 0.282 | 0.252 | true | true | unknown | unknown | unknown | null | null | null | null | null |
5ocx | H | L | 0 | A | peptide | null | cii-c-13-cit | IMMUNE SYSTEM | 07/04/17 | Crystal structure of ACPA E4 in complex with CII-C-13-CIT | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Dobritzsch, D., Ge, C., Holmdahl, R. | 1.75 | X-RAY DIFFRACTION | 0.212 | 0.176 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
5d9q | I | i | 0 | A | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM | 08/18/15 | Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 and scFv NIH45-46 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | null | human immunodeficiency virus 1 | Julien, J.-P., Stanfield, R.L., Ward, A.B., Wilson, I.A. | 4.4 | X-RAY DIFFRACTION | 0.320 | 0.290 | true | true | unknown | unknown | unknown | null | null | null | null | null |
4tvs | b | null | 0 | B | protein | null | vhh domain bs-1 | MEMBRANE PROTEIN | 06/27/14 | LAP1(aa356-583), H.sapiens, bound to VHH-BS1 | HOMO SAPIENS; VICUGNA PACOS | vicugna pacos | null | homo sapiens | Sosa, B.A., Schwartz, T.U. | 1.6 | X-RAY DIFFRACTION | 0.229 | 0.181 | false | false | IGHV1 | null | null | null | null | null | null | null |
7lab | H | L | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN, IMMUNE SYSTEM | 01/06/21 | Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1052 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Manne, K., Acharya, P. | 2.97 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3u9p | K | M | 0 | C | protein | null | neutrophil gelatinase-associated lipocalin | IMMUNE SYSTEM | 10/19/11 | Crystal Structure of Murine Siderocalin in Complex with an Fab Fragment | MUS MUSCULUS; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | mus musculus | Correnti, C., Strong, R.K. | 2.8 | X-RAY DIFFRACTION | 0.292 | 0.219 | false | true | IGHV2 | IGKV19 | Kappa | null | null | null | null | null |
7bnw | C | null | 0 | null | null | null | null | IMMUNE SYSTEM | 01/22/21 | Llama nanobody nb18 raised against GldL from Flavobacterium jonhsoniae | LAMA GLAMA | lama glama | null | null | Trinh, N.T., Cambillau, C., Leone, P. | 2.59 | X-RAY DIFFRACTION | 0.243 | 0.193 | false | true | IGHV1 | null | null | null | null | null | null | null |
7m30 | H | L | 0 | B | protein | null | envelope glycoprotein l | VIRAL PROTEIN/IMMUNE SYSTEM | 03/17/21 | Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25 | HUMAN CYTOMEGALOVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | human cytomegalovirus | Wrapp, D., McLellan, J.S. | 3.81 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7ws1 | I | H | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 01/28/22 | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Guo, H., Gao, Y., Ji, X., Yang, H. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6hhu | G | null | 0 | A | protein | null | s-layer protein sap | STRUCTURAL PROTEIN | 08/29/18 | Structure of the Bacillus anthracis Sap S-layer assembly domain | BACILLUS ANTHRACIS; LAMA GLAMA | lama glama | null | bacillus anthracis | Remaut, H., Fioravanti, A. | 2.7 | X-RAY DIFFRACTION | 0.250 | 0.186 | false | true | IGHV1 | null | null | null | null | null | null | null |
7phq | E | null | 0 | D | protein | null | divalent metal cation transporter mnth | MEMBRANE PROTEIN | 08/18/21 | Structure of homo-dimeric Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM | SYNTHETIC CONSTRUCT; STAPHYLOCOCCUS CAPITIS; LAMA GLAMA | synthetic construct | null | staphylococcus capitis | Bloch, J.S., Mukherjee, S., Kowal, J., Kossiakoff, A.A., Locher, K.P. | 8.45 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7tat | F | G | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 12/21/21 | SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (two receptor-binding domains open) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Park, Y.J., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
5w5x | H | L | 0 | A | protein | null | apoptosis regulator bax | APOPTOSIS/IMMUNE SYSTEM | 06/16/17 | Crystal structure of BAXP168G in complex with an activating antibody | HOMO SAPIENS; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | homo sapiens | Robin, A.Y., Colman, P.M., Czabotar, P.E. | 2.502 | X-RAY DIFFRACTION | 0.244 | 0.187 | false | false | IGHV1 | IGKV22 | Kappa | null | null | null | null | null |
4mhj | F | E | 0 | C | protein | null | hemagglutinin ha1 chain | VIRAL PROTEIN/IMMUNE SYSTEM | 08/29/13 | Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/goose/Guangdong/1/96 (H5N1) | INFLUENZA A VIRUS; MUS MUSCULUS | mus musculus | mus musculus | influenza a virus | Zhu, X., Wilson, I.A. | 6.98 | X-RAY DIFFRACTION | 0.387 | 0.377 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -12.278197 | BLI | null | TBD |
7pry | H | L | 0 | E | protein | null | surface glycoprotein | VIRAL PROTEIN | 09/22/21 | Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with COVOX-45 and beta-6 Fabs | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 3.1 | X-RAY DIFFRACTION | 0.291 | 0.245 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
6xxn | G | null | 0 | null | null | null | null | ANTITUMOR PROTEIN | 06/10/20 | Crystal structure of NB7, a nanobody targeting prostate specific membrane antigen | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Shahar, A., Rosenfeld, L., Papo, N. | 2.65 | X-RAY DIFFRACTION | 0.231 | 0.182 | false | true | IGHV1 | null | null | null | null | null | null | null |
6zhd | E | null | 0 | C | protein | null | spike glycoprotein,fibritin | ANTIVIRAL PROTEIN | 06/22/20 | H11-H4 bound to Spike | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; ENTEROBACTERIA PHAGE T4; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2, enterobacteria phage t4 | Clare, D.K., Naismith, J.H., Weckener, M., Vogirala, V.K. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3g6d | H | L | 0 | A | protein | null | interleukin-13 | IMMUNE SYSTEM | 02/06/09 | Crystal structure of the complex between CNTO607 Fab and IL-13 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Teplyakov, A., Obmolova, G., Gilliland, G.L. | 3.2 | X-RAY DIFFRACTION | 0.263 | 0.213 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -14.645409 | Unknown | null | TBD |
7df9 | H | L | 0 | A | V | protein | peptide | NA | NA | beta-arrestin-1 | vasopressin v2 receptor phosphopeptide | SIGNALING PROTEIN | 11/06/20 | Crystal of Arrestin2-V2Rpp-1-Fab30 complex | BOS TAURUS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | bos taurus | synthetic construct | Sun, J.P., Yu, X., Xiao, P., He, Q.T., Lin, J.Y., Zhu, Z.L. | 3.17 | X-RAY DIFFRACTION | 0.281 | 0.255 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7l0l | H | L | 0 | B | A | protein | protein | NA | NA | hemagglutinin ha2 chain | hemagglutinin ha1 chain | IMMUNE SYSTEM/Viral protein | 12/11/20 | Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer | HOMO SAPIENS; INFLUENZA A VIRUS (A/CANADA/720/2005(H2N2)) | homo sapiens | homo sapiens | influenza a virus (a/canada/720/2005(h2n2)) | influenza a virus (a/canada/720/2005(h2n2)) | Gorman, J., Kwong, P.D. | 2.85 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7lg6 | C | D | 0 | A | I | protein | protein | NA | NA | envelope glycoprotein gp120 | envelope glycoprotein gp41 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/19/21 | BG505 SOSIP.v5.2 in complex with VRC40.01 and RM19R Fabs | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Cottrell, C.A., Torres, J.L., Wu, N.R., Ward, A.B. | 3.28 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
7mej | A | null | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN/Immune System | 04/06/21 | CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb21 and Nb36 | LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | lama glama | null | severe acute respiratory syndrome coronavirus2 | Huang, W., Taylor, D.J. | 3.55 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6tej | C | null | 0 | B | protein | null | drug abc transporter atp-binding protein | MEMBRANE PROTEIN | 04/01/20 | Structure of apo IrtAB devoid SID in complex with sybody Syb_NL5 | MYCOLICIBACTERIUM THERMORESISTIBILE; SYNTHETIC CONSTRUCT | synthetic construct | null | mycolicibacterium thermoresistibile | Gonda, I., Arnold, F.M., Hutter, C.A.J., Weber, M.S., Seeger, M.A., Hurlimann, L.M. | 2.7 | X-RAY DIFFRACTION | 0.296 | 0.264 | false | true | IGHV1 | null | null | null | null | null | null | null |
7tht | d | b | 0 | V | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 01/12/22 | CryoEM structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Manne, K., May, A., Acharya, P. | 3.42 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4tvp | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/27/14 | Structure of BG505 SOSIP.664 in complex with broadly neutralizing antibodies, PGT122 and 35O22 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Pancera, M., Zhou, T., Kwong, P.D. | 3.1 | X-RAY DIFFRACTION | 0.248 | 0.214 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
6o23 | A | B | 0 | E | peptide | null | circumsporozoite protein | IMMUNE SYSTEM | 02/22/19 | Crystal structure of 2243 Fab in complex with circumsporozoite protein NANP5 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Scally, S.W., Bosch, A., Prieto, K., Murugan, R., Wardemann, H., Julien, J.P. | 2.0 | X-RAY DIFFRACTION | 0.224 | 0.186 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1b2w | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 12/01/98 | COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY | null | null | null | null | Fan, Z., Shan, L., Goldsteen, B.Z., Guddat, L.W., Thakur, A., Landolfi, N.F., Co, M.S., Vasquez, M., Queen, C., Ramsland, P.A., Edmundson, A.B. | 2.9 | X-RAY DIFFRACTION | 0.330 | 0.188 | false | false | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7om4 | B | null | 0 | A | protein | null | epidermal growth factor receptor | IMMUNE SYSTEM | 05/21/21 | Nanobody EgB4 bound to the full extracellular EGFR-EGF complex | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Zeronian, M.R., Janssen, B.J.C. | 6.05 | X-RAY DIFFRACTION | 0.327 | 0.296 | false | true | IGHV1 | null | null | null | null | null | null | null |
6wj1 | H | L | 0 | F | E | protein | protein | NA | NA | hemagglutinin ha2 chain | hemagglutinin ha1 chain | IMMUNE SYSTEM | 04/11/20 | Crystal structure of Fab 54-4H03 bound to H1 influenza hemagglutinin | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | influenza a virus | Wu, N.C., Wilson, I.A. | 3.503 | X-RAY DIFFRACTION | 0.232 | 0.179 | false | true | IGHV6 | IGKV3 | Kappa | null | null | null | null | null |
6ghg | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/07/18 | Variable heavy - variable light domain and Fab-arm CrossMabs with charged residue exchanges | HOMO SAPIENS | homo sapiens | homo sapiens | null | Regula, J., Imhof-Jung, S., Molhoj, M., Benz, J., Ehler, A., Bujotzek, A., Schaefer, W., Klein, C. | 1.88 | X-RAY DIFFRACTION | 0.226 | 0.195 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6iyn | A | null | 3 | null | null | null | null | AFLATOXIN B1-BINDING PROTEIN | 12/17/18 | Solution structure of camelid nanobody Nb26 against aflatoxin B1 | VICUGNA PACOS | vicugna pacos | null | null | Nie, Y., He, T., Zhu, J., Li, S.L., Hu, R., Yang, Y.H. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
5ja8 | F | null | 0 | E | protein | null | toxin higb-2 | TOXIN | 04/12/16 | Crystal structure of the HigB2 toxin in complex with Nb2 | LAMA GLAMA; VIBRIO CHOLERAE SEROTYPE O1 (STRAIN ATCC 39315 / EL TOR INABA N16961) | lama glama | null | vibrio cholerae serotype o1 (strain atcc 39315/ el tor inaba n16961) | Hadzi, S., Loris, R. | 2.49 | X-RAY DIFFRACTION | 0.248 | 0.201 | false | true | IGHV1 | null | null | null | null | null | null | null |
7kqy | C | null | 0 | null | null | null | null | IMMUNE SYSTEM | 11/18/20 | Crystal Structure and Characterization of Human Heavy-Chain only Antibodies reveals a novel, stable dimeric structure similar to Monoclonal Antibodies | HOMO SAPIENS | homo sapiens | null | null | Bahmanjah, S., Mieczkowski, C., Yu, Y., Baker, J., Raghunathan, G., Tomazela, D., Hsieh, M., Mccoy, M., Strickland, C., Fayadat-Dilman, L. | 2.913 | X-RAY DIFFRACTION | 0.260 | 0.207 | false | true | IGHV1 | null | null | null | null | null | null | null |
7lzp | E | null | 0 | D | protein | null | botulinum neurotoxin a light chain | ANTITOXIN | 03/10/21 | LC/A-JPU-B9-JPU-A11-JPU-G11 | CLOSTRIDIUM BOTULINUM; VICUGNA PACOS | vicugna pacos | null | clostridium botulinum | Lam, K., Jin, R. | 2.86 | X-RAY DIFFRACTION | 0.273 | 0.235 | false | true | IGHV1 | null | null | null | null | null | null | null |
4ong | H | L | 0 | P | peptide | null | amyloid beta a4 protein | IMMUNE SYSTEM | 01/28/14 | Fab fragment of 3D6 in complex with amyloid beta 1-40 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Feinberg, H., Saldanha, J.W., Diep, L., Goel, A., Widom, A., Veldman, G.M., Weis, W.I., Schenk, D., Basi, G.S. | 2.2 | X-RAY DIFFRACTION | 0.227 | 0.177 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
6o9i | D | E | 0 | C | protein | null | ecd | IMMUNE SYSTEM | 03/13/19 | Ternary complex of mouse ECD with Fab1 and Fab2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Min, X., Wang, Z. | 2.6 | X-RAY DIFFRACTION | 0.252 | 0.196 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3l95 | H | L | 0 | Y | protein | null | neurogenic locus notch homolog protein 1 | IMMUNE SYSTEM | 01/04/10 | Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of an antagonist antibody | HOMO SAPIENS; SYNTHETIC CONSTRUCT | null | null | homo sapiens | Hymowitz, S.G., de Leon, G.P. | 2.19 | X-RAY DIFFRACTION | 0.271 | 0.222 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -11.73 | SPR | 25 | 20393564 |
2rcj | M | P | 0 | null | null | null | null | IMMUNE SYSTEM | 09/20/07 | Solution structure of human Immunoglobulin M | HOMO SAPIENS | homo sapiens | homo sapiens | null | Perkins, S.J., Nealis, A.S., Sutton, B.J., Feinstein, A. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
4ckd | I | M | 0 | D | protein | null | beta-galactosidase | HYDROLASE/IMMUNE SYSTEM | 01/03/14 | Model of complex between the E.coli enzyme beta-galactosidase and four single chain Fv antibody domains scFv13R4. | MUS MUSCULUS; ESCHERICHIA COLI | mus musculus | mus musculus | escherichia coli | Vinothkumar, K.R., McMullan, G., Henderson, R. | 13.0 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
3vw3 | H | L | 0 | A | B | A | nucleic-acid | nucleic-acid | nucleic-acid | 64T | NA | NA | 5-HYDROXY-THYMIDINE-5'-MONOPHOSPHATE | dna (5'-d(*cp*cp*cp*gp*tp*cp*cp*ap*tp*ap*ap*tp*cp*ap*cp*tp*cp*g)-3') | dna (5'-d(*gp*cp*gp*ap*gp*tp*gp*ap*(64t)p*(5py)p*ap*tp*gp*gp*ap*cp*gp*g)-3') | IMMUNE SYSTEM/DNA | 07/30/12 | Antibody 64M-5 Fab in complex with a double-stranded DNA (6-4) photoproduct | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | | | | Yokoyama, H., Mizutani, R., Satow, Y. | 2.5 | X-RAY DIFFRACTION | 0.290 | 0.247 | false | false | IGHV1 | IGKV1 | Kappa | 0 | -9.082561 | Unknown | null | TBD |
7k8v | H | L | 0 | A | B | protein | protein | NA | NA | spike glycoprotein | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 09/27/20 | Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C110 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | severe acute respiratory syndrome coronavirus2 | Dam, K.A., Barnes, C.O., Bjorkman, P.J. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
6c6x | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 01/19/18 | Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque. | MACACA MULATTA | macaca mulatta | macaca mulatta | null | Joyce, M.G., Mascola, J.R., Graham, B.S., Kwong, P.D. | 1.99 | X-RAY DIFFRACTION | 0.208 | 0.176 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
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