pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7wwl | I | M | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 02/13/22 | S protein of Delta variant in complex with ZWD12 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Guo, Y.Y., Zhang, Y.Y., Zhou, Q. | 3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
4p2c | G | null | 0 | B | A | protein | protein | NA | NA | shiga toxin 2e, subunit b | shiga toxin 2e, subunit a | TOXIN | 03/03/14 | Complex of Shiga toxin 2e with a neutralizing single-domain antibody | ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | escherichia coli | escherichia coli | Lo, A.W.H., Moonens, K., De Kerpel, M., Brys, L., Pardon, E., Remaut, H., De Greve, H. | 2.818 | X-RAY DIFFRACTION | 0.253 | 0.187 | false | true | IGHV1 | null | null | null | null | null | null | null |
6a4k | H | L | 0 | A | protein | null | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 06/20/18 | Human antibody 32D6 Fab in complex with H1N1 influenza A virus HA1 | INFLUENZA A VIRUS (A/CALIFORNIA/7/2009(H1N1)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/california/7/2009(h1n1)) | Lee, C.C., Ko, T.P., Lin, L.L., Wang, A.H.J. | 3.15 | X-RAY DIFFRACTION | 0.233 | 0.175 | false | true | IGHV4 | IGLV4 | Lambda | null | null | null | null | null |
5f1k | D | null | 0 | B | protein | null | adp-ribosyl cyclase/cyclic adp-ribose hydrolase 1 | HYDROLASE/IMMUNE SYSTEM | 11/30/15 | human CD38 in complex with nanobody MU1053 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Zhang, H., Hao, Q. | 2.3 | X-RAY DIFFRACTION | 0.231 | 0.198 | false | true | IGHV1 | null | null | null | null | null | null | null |
5vxj | F | null | 0 | E | protein | null | invasin ipad | IMMUNE SYSTEM | 05/23/17 | 2.50 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JMK-E3 | SHIGELLA FLEXNERI; VICUGNA PACOS | vicugna pacos | null | shigella flexneri | Barta, M.L., Lovell, S., Battaile, K.P., Picking, W.D., Picking, W.L. | 2.5 | X-RAY DIFFRACTION | 0.259 | 0.196 | false | true | IGHV1 | null | null | null | null | null | null | null |
6w09 | I | M | 0 | E | protein | null | e2 glycoprotein | VIRUS/IMMUNE SYSTEM | 02/29/20 | Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain | CHIKUNGUNYA VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | chikungunya virus | Miller, A.S., Kuhn, R.J. | 5.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV9 | IGLV1 | Lambda | null | null | null | null | null |
6u2f | H | L | 0 | A | protein | null | proprotein convertase subtilisin/kexin type 9 | HYDROLASE/HYDROLASE INHIBITOR/IMMUNE SYSTEM | 08/19/19 | PCSK9-Fab 7G7 complex bound to cis-1-amino-4-phenylcyclohexaneacyl-WNLK(hR)IGLLR - NH2 | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Ultsch, M.H., Kirchhofer, D. | 2.94 | X-RAY DIFFRACTION | 0.209 | 0.174 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
5vxj | J | null | 0 | I | protein | null | invasin ipad | IMMUNE SYSTEM | 05/23/17 | 2.50 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JMK-E3 | SHIGELLA FLEXNERI; VICUGNA PACOS | vicugna pacos | null | shigella flexneri | Barta, M.L., Lovell, S., Battaile, K.P., Picking, W.D., Picking, W.L. | 2.5 | X-RAY DIFFRACTION | 0.259 | 0.196 | false | true | IGHV1 | null | null | null | null | null | null | null |
7e5s | J | T | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 02/20/21 | SARS-CoV-2 S trimer with four-antibody cocktail complex | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Sun, Y., Wang, L., Wang, N., Feng, R., Wang, X. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6y49 | H | L | 0 | L | Hapten | DEP | DIETHYL PHOSPHONATE | IMMUNE SYSTEM | 02/19/20 | Crystal structure of the paraoxon-modified A.17kappa antibody FAB fragment | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Chatziefthimiou, S., Mokrushina, Y., Smirnov, I., Gabibov, A., Wilmanns, M. | 1.65 | X-RAY DIFFRACTION | 0.215 | 0.179 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
7pij | N | null | 0 | B | protein | null | divalent metal cation transporter mnth | MEMBRANE PROTEIN | 08/20/21 | Structure of Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM | SYNTHETIC CONSTRUCT; STAPHYLOCOCCUS CAPITIS; LAMA GLAMA | synthetic construct | null | staphylococcus capitis | Bloch, J.S., Mukherjee, S., Kowal, J., Kossiakoff, A.A., Locher, K.P. | 3.47 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7te4 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 01/04/22 | Crystal structure of Fab2 anti-GluN2B antibody | MUS MUSCULUS | mus musculus | mus musculus | null | Tajima, N., Furukawa, H. | 2.456 | X-RAY DIFFRACTION | 0.297 | 0.261 | false | false | IGHV5 | IGKV19 | Kappa | null | null | null | null | null |
6x03 | D | null | 0 | null | null | null | null | STRUCTURAL PROTEIN | 05/15/20 | Nup84-Nup133 (aa521-1157) from S. cerevisiae bound by VHH-SAN8 and VHH-SAN9 | SACCHAROMYCES CEREVISIAE (STRAIN ATCC 204508 / S288C); VICUGNA PACOS | vicugna pacos | null | null | Nordeen, S.A., Schwartz, T.U. | 7.3 | X-RAY DIFFRACTION | 0.353 | 0.335 | false | true | IGHV1 | null | null | null | null | null | null | null |
7lu9 | q | r | 0 | d | protein | null | unknown | VIRAL PROTEIN/IMMUNE SYSTEM | 02/21/21 | Cryo-EM structure of DH851.3 bound to HIV-1 CH505 Env | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1 | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Manne, K., Edwards, R.J., Acharya, P. | 5.6 | ELECTRON MICROSCOPY | null | null | false | false | IGHV2 | IGLV2 | Lambda | null | null | null | null | null |
7ow1 | H | K | 0 | A | peptide | null | amyloid-beta precursor protein | IMMUNE SYSTEM | 06/16/21 | Crystal Structure of TAP01 in complex with amyloid beta peptide | Homo sapiens; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Hall, G., Cowan, R., Carr, M.D. | 1.4 | X-RAY DIFFRACTION | 0.200 | 0.152 | false | true | IGHV2 | IGKV10 | Kappa | null | null | null | null | null |
3b9k | D | C | 0 | F | protein | null | t-cell surface glycoprotein cd8 beta chain | IMMUNE SYSTEM | 11/05/07 | Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB | MUS MUSCULUS; RATTUS RATTUS | rattus rattus | rattus rattus | mus musculus | Shore, D., Wilson, I.A. | 2.7 | X-RAY DIFFRACTION | 0.284 | 0.235 | false | false | IGHV2 | IGKV19 | Kappa | null | null | null | null | null |
1yuh | B | A | 0 | B | Hapten | NP | 4-HYDROXY-3-NITROPHENYLACETYL-EPSILON-AMINOCAPROIC ACID | IMMUNOGLOBULIN | 01/30/96 | FAB FRAGMENT | MUS MUSCULUS | null | mus musculus | null | Yuhasz, S.C., Amzel, L.M., Parry, C., Strand, M. | 3.0 | X-RAY DIFFRACTION | unknown | 0.190 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
4msw | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | TRANSPORT PROTEIN | 09/18/13 | Y78 ester mutant of KcsA in high K+ | STREPTOMYCES LIVIDANS; MUS MUSCULUS | mus musculus | mus musculus | streptomyces lividans | Matulef, K., Valiyaveetil, F.I. | 2.06 | X-RAY DIFFRACTION | 0.229 | 0.196 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
4lf3 | E | D | 0 | F | protein | null | glucagon receptor | IMMUNE SYSTEM | 06/26/13 | Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Murray, J.M., Mukund, S. | 2.735 | X-RAY DIFFRACTION | 0.264 | 0.209 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4z0x | B | A | 0 | C | peptide | null | hcv e2 antigen (residues 432-446) | IMMUNE SYSTEM | 03/26/15 | Structure of Hepatitis C Virus Envelope glycoprotein E2 antigenic region 434-446 bound to the broadly neutralizing antibody HC26AM | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | hepatitis c virus | Rangarajan, S., Mariuzza, R.A. | 2.0 | X-RAY DIFFRACTION | 0.270 | 0.226 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
2ghw | B | b | 0 | A | protein | null | spike glycoprotein | VIRUS/VIRAL PROTEIN/ANTIBIOTIC | 03/27/06 | Crystal structure of SARS spike protein receptor binding domain in complex with a neutralizing antibody, 80R | SARS CORONAVIRUS; HOMO SAPIENS | homo sapiens | null | sars coronavirus | Hwang, W.C., Lin, Y., Santelli, E., Sui, J., Jaroszewski, L., Stec, B., Farzan, M., Marasco, W.A., Liddington, R.C. | 2.3 | X-RAY DIFFRACTION | 0.295 | 0.248 | true | true | unknown | unknown | unknown | null | null | null | null | null |
3wbd | A | a | 0 | null | null | null | null | IMMUNE SYSTEM | 05/14/13 | Crystal structure of anti-polysialic acid antibody single chain Fv fragment (mAb735) complexed with octasialic acid | SYNTHETIC CONSTRUCT | synthetic construct | null | null | Nagae, M., Ikeda, A., Hanashima, S., Kitajima, K., Sato, C., Yamaguchi, Y. | 1.8 | X-RAY DIFFRACTION | 0.259 | 0.233 | true | true | unknown | unknown | unknown | null | null | null | null | null |
2ajz | H | L | 0 | L | Hapten | ECG | 3-HYDROXY-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER | IMMUNE SYSTEM | 08/02/05 | Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with ecgonine methyl ester | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Zhu, X., Wilson, I.A. | 2.3 | X-RAY DIFFRACTION | 0.285 | 0.238 | false | false | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
7qnx | H | L | 0 | E | protein | null | surface glycoprotein | VIRAL PROTEIN | 12/23/21 | The receptor binding domain of SARS-CoV-2 spike glycoprotein in complex with Beta-55 and EY6A Fabs | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 2.92 | X-RAY DIFFRACTION | 0.266 | 0.229 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7fim | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | STRUCTURAL PROTEIN | 07/31/21 | Cryo-EM structure of the tirzepatide (LY3298176)-bound human GLP-1R-Gs complex | SYNTHETIC CONSTRUCT; RATTUS NORVEGICUS; BOS TAURUS; HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | bos taurus | rattus norvegicus | Zhao, F.H., Zhou, Q.T., Cong, Z.T., Hang, K.N., Zou, X.Y., Zhang, C., Chen, Y., Dai, A.T., Liang, A.Y., Ming, Q.Q., Wang, M., Chen, L.N., Xu, P.Y., Chang, R.L., Feng, W.B., Xia, T., Zhang, Y., Wu, B.L., Yang, D.H., Zhao, L.H., Xu, H.E., Wang, M.W. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
5anm | B | A | 0 | G | protein | null | ig epsilon chain c region | null | 09/07/15 | Crystal structure of IgE Fc in complex with a neutralizing antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Cohen, E.S., Dobson, C.L., Kack, H., Wang, B., Sims, D.A., Lloyd, C.O., England, E., Rees, D.G., Guo, H., Karagiannis, S.N., O'Brien, S., Persdotter, S., Ekdahl, H., Butler, R., Keyes, F., Oakley, S., Carlsson, M., Briend, E., Wilkinson, T., Anderson, I.K., Monk, P.D., vonWachenfeldt, K., Eriksson, P.O., Gould, H.J., V... | 2.85 | X-RAY DIFFRACTION | 0.25993 | 0.19553 | false | true | IGHV1 | IGLV1 | Lambda | 0 | -15.975251 | Kinetic Exclusion Assay | null | TBD |
1lo0 | H | L | 0 | H | Hapten | BC1 | 3-{[(9-CYANO-9,10-DIHYDRO-10-METHYLACRIDIN-9-YL)CARBONYL]AMINO}PROPANOIC ACID | IMMUNE SYSTEM | 05/05/02 | Catalytic Retro-Diels-Alderase Transition State Analogue Complex | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Hugot, M., Reymond, J.L., Baumann, U. | 2.0 | X-RAY DIFFRACTION | 0.255 | 0.206 | false | false | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7e23 | B | C | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 02/04/21 | SARS-CoV-2 spike in complex with the CA521 neutralizing antibody Fab (focused refinement on Fab-RBD) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Liu, C., Song, D., Dou, C. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
7sfv | O | P | 0 | E | protein | null | spike glycoprotein e2 | VIRUS/IMMUNE SYSTEM | 10/04/21 | CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP in complex with Fab hVEEV-63 | VENEZUELAN EQUINE ENCEPHALITIS VIRUS (STRAIN TC-83); HOMO SAPIENS | homo sapiens | homo sapiens | venezuelan equine encephalitis virus (straintc-83) | Binshtein, E., Crowe, J.E. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
5mp3 | H | L | 0 | D | peptide | null | microtubule-associated protein | IMMUNE SYSTEM | 12/15/16 | Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Skrabana, R., Novak, M., Cehlar, O., Kontsekova, E. | 2.75 | X-RAY DIFFRACTION | 0.250 | 0.199 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
3ley | H | L | 0 | P | peptide | null | envelope glycoprotein gp41 | IMMUNE SYSTEM | 01/15/10 | 2F5 Epitope scaffold elicited anti-HIV-1 monoclonal antibody 6a7 in complex with HIV-1 GP41 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | human immunodeficiency virus 1 | Ofek, G., Guenaga, F.J., Schief, W.R., Skinner, J., Baker, D., Wyatt, R., Kwong, P.D. | 1.99 | X-RAY DIFFRACTION | 0.215 | 0.177 | false | false | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7s3i | N | null | 0 | A | B | G | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | MEMBRANE PROTEIN | 09/07/21 | Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 2) | HOMO SAPIENS | homo sapiens | null | homo sapiens | homo sapiens | homo sapiens | Belousoff, M.J., Piper, S.J., Danev, R. | 2.51 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6e9i | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/01/18 | The crystal structure of bovine ultralong antibody BOV-4 | BOS TAURUS | bos taurus | bos taurus | null | Dong, J., Crowe, J.E. | 2.5 | X-RAY DIFFRACTION | 0.243 | 0.202 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5e94 | D | C | 0 | H | protein | null | glucagon-like peptide 1 receptor | MEMBRANE PROTEIN | 10/14/15 | Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Soroka, V., Schluckebier, G., Reedtz-Runge, S. | 2.0 | X-RAY DIFFRACTION | 0.232 | 0.188 | false | true | IGHV3 | IGKV10 | Kappa | null | null | null | null | null |
1rzi | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 12/24/03 | Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D. | 2.9 | X-RAY DIFFRACTION | 0.321 | 0.233 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7lmp | null | A | 0 | B | Hapten | NY6 | 3-[2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl]-8-(1~{H}-imidazol-5-ylcarbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione | IMMUNE SYSTEM | 02/05/21 | Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 36 [3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-8-(1H-imidazole-4-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione] | HOMO SAPIENS | null | homo sapiens | homo sapiens | Yan, N.L., Wilson, I.A., Kelly, J.W. | 2.29 | X-RAY DIFFRACTION | 0.264 | 0.203 | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
5boz | K | null | 0 | E | protein | null | ricin | Hydrolase/Immune system | 05/27/15 | Ricin A chain bound to camelid nanobody (VHH9)(E1) | RICINUS COMMUNIS; LAMA GLAMA | lama glama | null | ricinus communis | Rudolph, M.J., Mantis, N. | 3.1 | X-RAY DIFFRACTION | 0.277 | 0.215 | false | true | IGHV1 | null | null | 0 | -12.489521 | SPR | null | TBD |
5t33 | H | L | 0 | G | protein | null | rhpa gp120 core | IMMUNE SYSTEM | 08/24/16 | Crystal structure of strain-specific glycan-dependent CD4 binding site-directed neutralizing antibody CAP257-RH1, in complex with HIV-1 strain RHPA gp120 core with an oligomannose N276 glycan. | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS | homo sapiens | homo sapiens | human immunodeficiency virus | Wibmer, C.K., Gorman, J., Kwong, P.D. | 3.2092 | X-RAY DIFFRACTION | 0.269 | 0.229 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
3mlx | H | L | 0 | P | peptide | null | hiv-1 gp120 third variable region (v3) crown | IMMUNE SYSTEM | 04/18/10 | Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with an MN V3 peptide | HOMO SAPIENS; HIV-1 M:B_MN | homo sapiens | homo sapiens | hiv-1 m | Kong, X.-P. | 1.9 | X-RAY DIFFRACTION | 0.228 | 0.192 | false | false | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
6xxn | C | null | 0 | null | null | null | null | ANTITUMOR PROTEIN | 06/10/20 | Crystal structure of NB7, a nanobody targeting prostate specific membrane antigen | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Shahar, A., Rosenfeld, L., Papo, N. | 2.65 | X-RAY DIFFRACTION | 0.231 | 0.182 | false | true | IGHV1 | null | null | null | null | null | null | null |
4hg4 | J | K | 0 | A | protein | null | hemagglutinin ha2 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/06/12 | Crystal structure of Fab 2G1 in complex with a H2N2 influenza virus hemagglutinin | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Xu, R., Wilson, I.A. | 3.2 | X-RAY DIFFRACTION | 0.302 | 0.249 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6med | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 09/06/18 | Broadly neutralizing antibodies against HCV use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design | HOMO SAPIENS | homo sapiens | homo sapiens | null | Flyak, A.I., Bjorkman, P.J. | 2.04 | X-RAY DIFFRACTION | 0.216 | 0.182 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4z5r | S | R | 0 | H | protein | null | interferon alpha-2 | Cytokine/Immune System | 04/02/15 | Rontalizumab Fab bound to Interferon-a2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Eigenbrot, C., Maurer, B., Bosanac, I. | 3.0 | X-RAY DIFFRACTION | 0.251 | 0.223 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -14.658431 | SPR | null | TBD |
5njd | X | W | 0 | E | H | protein | protein | NA | NA | interleukin-12 subunit beta | interleukin-23 subunit alpha | IMMUNE SYSTEM | 03/28/17 | Structure of Interleukin 23 in complex with Briakinumab FAb | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Bloch, Y., Savvides, S.N. | 3.9 | X-RAY DIFFRACTION | 0.312 | 0.272 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
1qlr | B | A | 0 | null | null | null | null | IMMUNOGLOBULIN | 09/11/99 | CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF A HUMAN MONOCLONAL IgM COLD AGGLUTININ | HOMO SAPIENS | homo sapiens | homo sapiens | null | Carvalho, J.G., Cauerhff, A., Goldbaum, F., Leoni, J., Polikarpov, I. | 2.83 | X-RAY DIFFRACTION | 0.265 | 0.216 | false | false | IGHV4 | IGKV3D | Kappa | null | null | null | null | null |
4mau | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/16/13 | Crystal structure of anti-ST2L antibody C2244 | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L. | 1.9 | X-RAY DIFFRACTION | 0.217 | 0.184 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7ncs | H | L | 0 | A | protein | null | outer membrane protein assembly factor bama | MEMBRANE PROTEIN | 01/29/21 | Lateral-open conformation of the lid-locked BAM complex (BamA E435C S665C, BamBDCE) bound by a bactericidal Fab fragment | ESCHERICHIA COLI K-12; HOMO SAPIENS | homo sapiens | homo sapiens | escherichia coli k-12 | Haysom, S.F., Machin, J.M. | 7.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV12 | Kappa | null | null | null | null | null |
7l7e | O | P | 0 | K | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 12/28/20 | Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibodies AZD8895 and AZD1061 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Dong, J., Crowe, J.E. | 3.0 | X-RAY DIFFRACTION | 0.273 | 0.215 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6mpg | 8 | 7 | 0 | 2 | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN | 10/06/18 | Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Kwong, P.D. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
6shg | H | L | 0 | B | protein | null | roab13 fab heavy chain (constant domain) | IMMUNE SYSTEM | 08/06/19 | Diffraction data for RoAb13 crystal co-crystallised with PIYDIN and its RoAb13 structure | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Saridakis, E., Helliwell, J.R., Govada, L., Chain, B., Morgan, M., Kassen, S.C., Chayen, N.E. | 3.093 | X-RAY DIFFRACTION | 0.325 | 0.270 | false | true | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
5uqy | H | G | 0 | E | J | protein | protein | NA | NA | envelope glycoprotein gp1 | envelope glycoprotein gp2 | VIRAL PROTEIN/IMMUNE SYSTEM | 02/08/17 | Crystal structure of Marburg virus GP in complex with the human survivor antibody MR78 | LAKE VICTORIA MARBURGVIRUS (STRAIN RAVN-87); HOMO SAPIENS | homo sapiens | homo sapiens | lake victoria marburgvirus (strain ravn-87) | lake victoria marburgvirus (strain ravn-87) | Hashiguchi, T., Fusco, M.L., Hastie, K.M., Bomholdt, Z.A., Lee, J.E., Flyak, A.I., Matsuoka, R., Kohda, D., Yanagi, Y., Hammel, M., Crowe, J.E., Saphire, E.O. | 3.6 | X-RAY DIFFRACTION | 0.262 | 0.221 | false | false | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6pci | H | K | 0 | A | protein | null | virion spike glycoprotein | immune system, viral protein | 06/17/19 | EBOV GPdMuc (Makona) in complex with rEBOV-520 and rEBOV-548 Fabs | EBOLA VIRUS; HOMO SAPIENS; ZAIRE EBOLAVIRUS | homo sapiens | homo sapiens | ebola virus | Ward, A.B., Murin, C.D., Alkutkar, T. | 4.12 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6z20 | B | null | 0 | A | protein | null | cd9 antigen | CELL ADHESION | 05/14/20 | Structure of the EC2 domain of CD9 in complex with nanobody 4C8 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Oosterheert, W., Manshande, J., Pearce, N.M., Lutz, M., Gros, P. | 2.68 | X-RAY DIFFRACTION | 0.248 | 0.206 | false | true | IGHV1 | null | null | null | null | null | null | null |
6vlr | E | M | 0 | G | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/24/20 | BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; MACACA MULATTA | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Cottrell, C.A., Ward, A.B. | 4.42 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
5ovw | J | null | 0 | D | protein | null | vitamin b12-binding protein | TRANSPORT PROTEIN | 08/30/17 | Nanobody-bound BtuF, the vitamin B12 binding protein in Escherichia coli | ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | escherichia coli | Mireku, S.A., Sauer, M.M., Glockshuber, R., Locher, K.P. | 2.653 | X-RAY DIFFRACTION | 0.259 | 0.223 | false | true | IGHV1 | null | null | null | null | null | null | null |
2vyr | F | null | 0 | B | protein | null | mdm4 protein | IMMUNE SYSTEM | 07/28/08 | Structure of human MDM4 N-terminal domain bound to a single domain antibody | HOMO SAPIENS | homo sapiens | null | homo sapiens | Yu, G.W., Vaysburd, M., Allen, M.D., Settanni, G., Fersht, A.R. | 2.0 | X-RAY DIFFRACTION | 0.248 | 0.207 | false | true | IGHV3 | null | null | 0 | -9.69 | ITC | 15 | 19084022 |
5e03 | A | null | 0 | null | null | null | null | SIGNALING PROTEIN | 09/28/15 | Crystal structure of mouse CTLA-4 nanobody | MUS MUSCULUS | mus musculus | null | null | Fedorov, A.A., Fedorov, E.V., Samanta, D., Almo, S.C. | 1.685 | X-RAY DIFFRACTION | 0.189 | 0.171 | false | true | IGHV1 | null | null | null | null | null | null | null |
6vi1 | H | G | 0 | P | peptide | null | terminase, large subunit | IMMUNE SYSTEM | 01/11/20 | Structure of Fab4 bound to P22 TerL(1-33) | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | salmonella phage p22 | Cingolani, G., Lokareddy, R., Ko, Y. | 2.4 | X-RAY DIFFRACTION | 0.239 | 0.189 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4gag | H | L | 0 | P | peptide | null | genome polyprotein | IMMUNE SYSTEM | 07/25/12 | Structure of the broadly neutralizing antibody AP33 in complex with its HCV epitope (E2 residues 412-423) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | hepatitis c virus (isolate glasgow) | Potter, J.A., Owsianka, A., Angus, A.G.N., Jeffery, N., Matthews, D., Keck, Z., Lau, P., Foung, S.K.H., Taylor, G.L., Patel, A.H. | 1.8 | X-RAY DIFFRACTION | 0.211 | 0.178 | false | false | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
3grw | H | L | 0 | A | protein | null | fibroblast growth factor receptor 3 | TRANSFERASE/IMMUNE SYSTEM | 03/26/09 | FGFR3 in complex with a Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wiesmann, C. | 2.1 | X-RAY DIFFRACTION | 0.228 | 0.189 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7k8r | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/27/20 | Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C135 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Jette, C.A., Barnes, C.O., Bjorkman, P.J. | 2.0 | X-RAY DIFFRACTION | 0.237 | 0.195 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4k07 | null | F | 0 | null | null | null | null | IMMUNE SYSTEM | 04/03/13 | Crystal structure of the amyloid-forming immunoglobulin AL-103 cis-proline 95 mutant | HOMO SAPIENS | null | homo sapiens | null | Thompson, J.R., Berkholz, D.S., Mahlum, E.W., Ramirez-Alvarado, M. | 2.83 | X-RAY DIFFRACTION | 0.236 | 0.202 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
6vja | I | M | 0 | D | protein | null | b-lymphocyte antigen cd20 | IMMUNE SYSTEM | 01/15/20 | Structure of CD20 in complex with rituximab Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Rohou, A., Croll, T.I. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
7pc2 | M | N | 0 | C | protein | null | gp120, bg505 sosip.664 t332n | VIRAL PROTEIN | 08/03/21 | HIV-1 Env (BG505 SOSIP.664) in complex with the IgA bNAb 7-269 and the antibody 3BNC117. | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS | homo sapiens | homo sapiens | human immunodeficiency virus | Fernandez, I., Bontems, F., Pehau-Arnaudet, G., Rey, F. | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6z3k | J | K | 0 | null | null | null | null | IMMUNE SYSTEM | 05/20/20 | Structure of protective antibody 38-1-10A Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Zhou, D., Fry, E.E., Ren, J., Stuart, D.I. | 2.7 | X-RAY DIFFRACTION | 0.234 | 0.188 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
7ra8 | F | G | 0 | E | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/30/21 | SARS-CoV-2 S glycoprotein in complex with S2X259 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Veesler, D., Tortorici, M.A., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7mzk | N | M | 0 | B | protein | null | spike protein s1 | VIRAL PROTEIN | 05/24/21 | SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 and Fab PDI 96 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Pymm, P., Dietrich, M.H., Tan, L.L., Chan, L.J., Tham, W.H. | 2.25 | X-RAY DIFFRACTION | 0.235 | 0.197 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
5zia | K | M | 0 | N | peptide | null | phosphorylated tau peptide | IMMUNE SYSTEM | 03/14/18 | Crystal structure of human anti-tau antibody CBTAU-24.1 in complex with its phosphorylated tau peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Zhang, H., Wilson, I.A. | 2.603 | X-RAY DIFFRACTION | 0.249 | 0.200 | false | true | IGHV1 | IGKV4 | Kappa | 0 | -8.898799 | Unknown | null | TBD |
6bt3 | F | E | 0 | L | protein | null | major capsid protein l1 | VIRUS | 12/05/17 | High-Resolution Structure Analysis of Antibody V5 Conformational Epitope on Human Papillomavirus 16 | MUS MUSCULUS; HUMAN PAPILLOMAVIRUS TYPE 16 | mus musculus | mus musculus | human papillomavirus type 16 | Guan, J., Bywaters, S.M., Brendle, S.A., Ashley, R.E., Makhov, A.M., Conway, J.F., Christensen, N.D., Hafenstein, S. | 4.7 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
5m7q | B | null | 0 | null | null | null | null | IMMUNE SYSTEM | 10/28/16 | Engineering the Thermostability of Nanobodies - NbD2 | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Soler, N., Kunz, P., Muyldermans, S. | 1.8 | X-RAY DIFFRACTION | 0.249 | 0.196 | false | true | IGHV1 | null | null | null | null | null | null | null |
5cex | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 07/07/15 | Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies | HOMO SAPIENS | homo sapiens | homo sapiens | null | Garces, F., Wilson, I.A. | 2.105 | X-RAY DIFFRACTION | 0.244 | 0.200 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
5wn9 | H | h | 0 | A | peptide | null | major surface glycoprotein g | VIRAL PROTEIN/IMMUNE SYSTEM | 07/31/17 | Structure of antibody 2D10 bound to the central conserved region of RSV G | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | null | human respiratory syncytial virus a (straina2) | Fedechkin, S.O., George, N.L., Wolff, J.T., Kauvar, L.M., DuBois, R.M. | 1.551 | X-RAY DIFFRACTION | 0.185 | 0.169 | true | true | unknown | unknown | unknown | null | null | null | null | null |
3ivk | H | L | 0 | M | nucleic-acid | null | class i ligase product | immune system / RNA | 09/01/09 | Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Koldobskaya, Y., Duguid, E.M., Shechner, D.M., Koide, S., Kossiakoff, A.A., Bartel, D.P., Piccirilli, J.A. | 3.1 | X-RAY DIFFRACTION | 0.225 | 0.207 | false | true | IGHV5 | IGKV15 | Kappa | null | null | null | null | null |
5vsh | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 05/11/17 | CH1/Clambda Fab based on Pertuzumab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Hendle, J. | 2.55 | X-RAY DIFFRACTION | 0.255 | 0.207 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2ny4 | D | C | 0 | A | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/20/06 | HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E268C, S334A, S375W) Complexed with CD4 and Antibody 17b | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D. | 2.0 | X-RAY DIFFRACTION | 0.241 | 0.202 | false | true | IGHV1 | IGKV3 | Kappa | 0 | null | SPR | null | 17301785 |
6bfs | H | L | 0 | C | protein | null | granulocyte-macrophage colony-stimulating factor | IMMUNE SYSTEM | 10/26/17 | The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Dhagat, U., Hercus, T.R., Broughton, S.E., Nero, T.L., Lopez, A.F., Parker, M.W. | 2.0 | X-RAY DIFFRACTION | 0.248 | 0.182 | false | true | IGHV1 | IGKV15 | Kappa | null | null | null | null | null |
6hf1 | F | E | 0 | D | protein | null | sulfhydryl oxidase 1 | OXIDOREDUCTASE | 08/21/18 | Mutant oxidoreductase fragment of mouse QSOX1 in complex with an antibody Fab | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Grossman-Haham, I., Fass, D. | 1.94 | X-RAY DIFFRACTION | 0.231 | 0.194 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6lht | H | L | 0 | C | A | B | E | D | protein | protein | protein | protein | protein | NA | NA | NA | NA | NA | vp1 protein | vp1 protein | vp1 protein | vp1 protein | vp1 protein | VIRAL PROTEIN | 12/10/19 | Localized reconstruction of coxsackievirus A16 mature virion in complex with Fab 18A7 | MUS MUSCULUS; COXSACKIEVIRUS A16 | mus musculus | mus musculus | coxsackievirus a16 | coxsackievirus a16 | coxsackievirus a16 | coxsackievirus a16 | coxsackievirus a16 | He, M.Z., Xu, L.F., Zheng, Q.B., Zhu, R., Yin, Z.C., Cheng, T., Li, S.W. | 3.67 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7jum | H | h | 0 | A | protein | null | gametocyte surface protein p230 | CELL INVASION | 08/20/20 | Pfs230 D1 domain in complex with neutralizing antibody LMIV230-01 | PLASMODIUM FALCIPARUM (ISOLATE 3D7); HOMO SAPIENS | homo sapiens | null | plasmodium falciparum (isolate 3d7) | Tolia, N., Tang, W.K. | 1.998 | X-RAY DIFFRACTION | 0.233 | 0.191 | true | true | unknown | unknown | unknown | null | null | null | null | null |
2yc1 | D | E | 0 | F | protein | null | beta-mammal toxin cn2 | IMMUNE SYSTEM/TOXIN | 03/10/11 | Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann | HOMO SAPIENS; CENTRUROIDES NOXIUS HOFFMANN | homo sapiens | homo sapiens | centruroides noxius hoffmann | Canul-Tec, J.C., Riano-Umbarila, L., Rudino-Pinera, E., Becerril, B., Possani, L.D., Torres-Larios, A. | 1.9 | X-RAY DIFFRACTION | 0.21212 | 0.18613 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
4odw | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 01/10/14 | Unliganded Fab structure of lipid A-specific antibody A6 | MUS MUSCULUS | mus musculus | mus musculus | null | Haji-Ghassemi, O., Evans, S.V. | 2.72 | X-RAY DIFFRACTION | 0.257 | 0.231 | false | false | IGHV5 | IGKV10 | Kappa | null | null | null | null | null |
5jym | B | b | 0 | A | protein | null | cadherin-3 | CELL ADHESION/IMMUNE SYSTEM | 05/14/16 | Human P-cadherin EC12 with scFv TSP11 bound | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Caaveiro, J.M.M., Kudo, S., Tsumoto, K. | 2.45 | X-RAY DIFFRACTION | 0.270 | 0.223 | true | true | unknown | unknown | unknown | null | null | null | null | null |
3k80 | A | null | 0 | C | protein | null | mp18 rna editing complex protein | Immune System, RNA Binding Protein | 10/13/09 | Structure of essential protein from Trypanosoma brucei | LAMA GLAMA; TRYPANOSOMA BRUCEI | lama glama | null | trypanosoma brucei | Wu, M. | 2.4 | X-RAY DIFFRACTION | 0.277 | 0.223 | false | true | IGHV1 | null | null | null | null | null | null | null |
3bsz | H | L | 0 | F | protein | null | plasma retinol-binding protein | TRANSPORT PROTEIN/IMMUNE SYSTEM | 12/27/07 | Crystal structure of the transthyretin-retinol binding protein-Fab complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Zanotti, G., Cendron, L., Gliubich, F., Folli, C., Berni, R. | 3.38 | X-RAY DIFFRACTION | 0.312 | 0.239 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5kan | G | I | 0 | D | E | protein | protein | NA | NA | hemagglutinin ha2 | hemagglutinin ha1 | IMMUNE SYSTEM | 06/01/16 | Crystal structure of multidonor HV1-18-class broadly neutralizing Influenza A antibody 16.g.07 in complex with A/Hong Kong/1-4-MA21-1/1968 (H3N2) Hemagglutinin | INFLUENZA A VIRUS (STRAIN A/HONG KONG/1/1968 H3N2); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (strain a/hong kong/1/1968h3n2) | influenza a virus (strain a/hong kong/1/1968h3n2) | Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D. | 2.785 | X-RAY DIFFRACTION | 0.243 | 0.218 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4xbp | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 12/17/14 | Crystal structure of human 4E10 Fab crystalized in the presence of Phosphatidylethanolamine (06:0 PE) | HOMO SAPIENS | homo sapiens | homo sapiens | null | Irimia, A., Stanfield, R.L., Wilson, I.A. | 2.94 | X-RAY DIFFRACTION | 0.271 | 0.228 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3wih | I | M | 0 | B | protein | null | roundabout homolog 1 | IMMUNE SYSTEM | 09/12/13 | Crystal structure of the third fibronectin domain (Fn3) of human ROBO1 in complex with the Fab fragment of murine monoclonal antibody B2212A. | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Nakayama, T., Mizohata, E., Yamashita, T., Nagatoishi, M., Iwanari, H., Mochizuki, Y., Kado, Y., Yokota, Y., Sato, R., Tsumoto, K., Fujitani, H., Kodama, T., Hamakubo, T., Inoue, T. | 1.701 | X-RAY DIFFRACTION | 0.236 | 0.189 | false | false | IGHV1 | IGKV10 | Kappa | 0 | -10.533665 | ITC | null | TBD |
4tnw | J | M | 0 | E | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | TRANSPORT PROTEIN/IMMUNE SYSTEM | 06/05/14 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and POPC in a lipid-modulated conformation | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Althoff, T., Hibbs, R.E., Banerjee, S., Gouaux, E. | 3.2 | X-RAY DIFFRACTION | 0.251 | 0.227 | false | false | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7mhr | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | MEMBRANE PROTEIN | 04/15/21 | KcsA E71V closed gate with K+ | MUS MUSCULUS; STREPTOMYCES LIVIDANS | mus musculus | mus musculus | streptomyces lividans | Rohaim, A., Li, J., Weingarth, M., Roux, B. | 2.77 | X-RAY DIFFRACTION | 0.203 | 0.168 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
5ock | H | L | 0 | A | peptide | null | cep1 peptide (from enolase) | IMMUNE SYSTEM | 07/03/17 | Crystal structure of ACPA E4 in complex with CEP1 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Dobritzsch, D., Ge, C., Holmdahl, R. | 1.6 | X-RAY DIFFRACTION | 0.218 | 0.183 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
6fg1 | A | D | 0 | null | null | null | null | IMMUNE SYSTEM | 01/09/18 | CRYSTAL STRUCTURE OF FAB OF NATALIZUMAB IN COMPLEX WITH FAB OF NAA32. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bertrand, T., Pouzieux, S. | 2.03 | X-RAY DIFFRACTION | 0.285 | 0.266 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4uu9 | A | B | 0 | C | protein | null | complement c5 | null | 07/25/14 | Crystal structure of the human c5a in complex with MEDI7814 a neutralising antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Colley, C., Sridharan, S., Dobson, C., Popovic, B., Debreczeni, J.E., Hargreaves, D., Edwards, B., Brennan, J., England, L., Fung, S., An Eghobamien, L., Sivars, U., Woods, R., Flavell, L., Renshaw, G.J., Wickson, K., Wilkinson, T., Davies, R., Bonnell, J., Warrener, P., Howes, R., Vaughan, T. | 2.12 | X-RAY DIFFRACTION | 0.20163 | 0.17456 | false | true | IGHV3 | IGLV2 | Lambda | 0 | -14.807331 | SPR | null | TBD |
7kqk | A | B | 0 | C | peptide | null | ptau peptide | IMMUNE SYSTEM | 11/16/20 | anti-pTau C21-ABS Fab in complex with pTau peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Mosyak, L., Brinth, A. | 2.6 | X-RAY DIFFRACTION | 0.231 | 0.211 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
6gjq | H | null | 0 | G | protein | null | cystic fibrosis transmembrane conductance regulator | HYDROLASE | 05/16/18 | human NBD1 of CFTR in complex with nanobody T27 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C. | 2.49 | X-RAY DIFFRACTION | 0.240 | 0.199 | false | true | IGHV1 | null | null | null | null | null | null | null |
3j8z | F | J | 0 | D | protein | null | l1 | VIRUS/IMMUNE SYSTEM | 11/20/14 | Cryo-EM reconstruction of quasi-HPV16 complex with H16.1A Fab | HUMAN PAPILLOMAVIRUS TYPE 16; MUS MUSCULUS | mus musculus | mus musculus | human papillomavirus type 16 | Guan, J., Hafenstein, S. | 14 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
6qna | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/10/19 | Structure of bovine anti-RSV hybrid Fab B13HC-B4LC | BOS TAURUS | bos taurus | bos taurus | null | Ren, J., Nettleship, J.E., Harris, G., Mwangi, W., Rhaman, N., Grant, C., Kotecha, A., Fry, E., Charleston, B., Stuart, D.I., Hammond, J., Owens, R.J. | 2.62 | X-RAY DIFFRACTION | 0.250 | 0.220 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7f4h | S | s | 0 | A | G | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | MEMBRANE PROTEIN | 06/18/21 | Cryo-EM structure of afamelanotide-bound melanocortin-1 receptor in complex with Gs protein, Nb35 and scFv16 | HOMO SAPIENS; SYNTHETIC CONSTRUCT; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | homo sapiens | Ma, S., Chen, Y., Dai, A., Yin, W., Guo, J., Yang, D., Zhou, F., Jiang, Y., Wang, M.-W., Xu, H.E. | 2.7 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6ey6 | P | null | 0 | H | protein | null | t9ss component cytoplasmic membrane protein porm | PROTEIN TRANSPORT | 11/10/17 | C-terminal part (residues 315-516) of PorM with the llama naobody nb130 | PORPHYROMONAS GINGIVALIS; LAMA GLAMA | lama glama | null | porphyromonas gingivalis | Leone, P., Cambillau, C., Roussel, A. | 2.1 | X-RAY DIFFRACTION | 0.215 | 0.181 | false | true | IGHV1 | null | null | null | null | null | null | null |
5t6p | B | A | 0 | F | peptide | null | muc1 peptide fragment | IMMUNE SYSTEM | 09/01/16 | Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Brooks, C.L., Movahedin, M. | 1.97 | X-RAY DIFFRACTION | 0.232 | 0.221 | false | true | IGHV5 | IGKV1 | Kappa | 0.000001 | -8.261204 | Unknown | null | TBD |
7lf2 | P | N | 0 | Q | protein | null | arginase-1 | HYDROLASE/IMMUNE SYSTEM | 01/15/21 | Trimeric human Arginase 1 in complex with mAb4 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gomez-Llorente, Y., Scapin, G., Palte, R.L. | 3.72 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
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