pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2x1q | B | null | 0 | null | null | null | null | CONTRACTILE PROTEIN | 01/03/10 | Gelsolin Nanobody | LAMA GLAMA | lama glama | null | null | VandenAbbeele, A., DeClercq, S., DeGanck, A., DeCorte, V., VanLoo, B., Srinivasan, V., Steyaert, J., Vandekerckhove, J., Gettemans, J. | 1.06 | X-RAY DIFFRACTION | 0.229 | 0.213 | false | true | IGHV1 | null | null | null | null | null | null | null |
1zvh | A | null | 0 | L | protein | null | lysozyme c | HYDROLASE/IMMUNE SYSTEM | 06/02/05 | Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme | CAMELUS DROMEDARIUS; GALLUS GALLUS | camelus dromedarius | null | gallus gallus | De Genst, E., Silence, K., Decanniere, K., Conrath, K., Loris, R., Kinne, J., Muyldermans, S., Wyns, L. | 1.5 | X-RAY DIFFRACTION | 0.234 | 0.208 | false | true | IGHV1 | null | null | null | null | null | null | null |
7tzh | A | a | 0 | B | protein | null | lymphocyte activation gene 3 protein | IMMUNOSUPPRESSANT | 02/15/22 | LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition | HOMO SAPIENS | homo sapiens | null | homo sapiens | Ming, Q., Tran, T.H., Luca, V.C. | 2.43 | X-RAY DIFFRACTION | 0.255 | 0.212 | true | true | unknown | unknown | unknown | null | null | null | null | null |
3ggw | D | C | 0 | F | peptide | null | peptide b1 | IMMUNE SYSTEM | 03/02/09 | Crystal Structure of FAB F22-4 in complex with a Carbohydrate-mimetic peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Saul, F.A., Vulliez-Le Normand, B., Bentley, G.A. | 1.7 | X-RAY DIFFRACTION | 0.245 | 0.197 | false | false | IGHV6 | IGKV2 | Kappa | 0.000003 | -7.55 | ITC | 25 | 19328810 |
4jn1 | H | L | 0 | null | null | null | null | immune system | 03/14/13 | An Antidote for Dabigatran | MUS MUSCULUS | mus musculus | mus musculus | null | Schiele, F., Nar, H. | 1.89 | X-RAY DIFFRACTION | 0.197 | 0.176 | false | true | IGHV4 | IGKV2 | Kappa | null | null | null | null | null |
7tyx | N | null | 0 | A | B | G | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | MEMBRANE PROTEIN | 02/14/22 | Human Amylin2 Receptor in complex with Gs and rat amylin peptide | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | homo sapiens | Cao, J., Belousoff, M.J., Johnson, R.M., Wootten, D.L., Sexton, P.M. | 2.55 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7d85 | E | F | 0 | D | protein | null | receptor tyrosine-protein kinase erbb-3 | IMMUNE SYSTEM | 10/07/20 | Crystal structure of anti-ErbB3 Fab ISU104 in complex with human ErbB3 extracellular domain 3 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Yoo, Y., Cho, H.S. | 2.5 | X-RAY DIFFRACTION | 0.258 | 0.203 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
2rcj | I | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/20/07 | Solution structure of human Immunoglobulin M | HOMO SAPIENS | homo sapiens | homo sapiens | null | Perkins, S.J., Nealis, A.S., Sutton, B.J., Feinstein, A. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7mk6 | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | MEMBRANE PROTEIN | 04/21/21 | KcsA open gate E71V mutant with sodium | SYNTHETIC CONSTRUCT; STREPTOMYCES LIVIDANS | synthetic construct | synthetic construct | streptomyces lividans | Rohaim, A., Li, J., Weingarth, M., Roux, B. | 3.1 | X-RAY DIFFRACTION | 0.253 | 0.208 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3q6f | L | K | 0 | null | null | null | null | IMMUNE SYSTEM | 12/31/10 | Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Spurrier, B., Sampson, J., Totrov, M., Li, H., O'Neal, T., William, C., Robinson, J., Gorny, M.K., Zolla-Pazner, S., Kong, X.P. | 3.192 | X-RAY DIFFRACTION | 0.243 | 0.199 | false | false | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
5gs2 | D | d | 0 | B | protein | null | repebody | SUGAR BINDING PROTEIN/IMMUNE SYSTEM | 08/13/16 | Crystal structure of diabody complex with repebody and MBP | MUS MUSCULUS; HOMO SAPIENS; ESCHERICHIA COLI (STRAIN K12); ESCHERICHIA COLI | mus musculus | null | escherichia coli | Kim, J.H., Song, D.H., Youn, S.J., Kim, J.W., Cho, G., Lee, H., Lee, J.O. | 3.592 | X-RAY DIFFRACTION | 0.278 | 0.217 | true | true | unknown | unknown | unknown | null | null | null | null | null |
3qg6 | B | A | 0 | D | peptide | null | agr autoinducing peptide | IMMUNE SYSTEM/INHIBITOR | 01/24/11 | Structural Basis for Ligand Recognition and Discrimination of a Quorum Quenching Antibody | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Kirchdoerfer, R.N., Janda, J.D., Kaufmann, G.F, Wilson, I.A | 2.5 | X-RAY DIFFRACTION | 0.239 | 0.184 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2kqn | null | B | 15 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the AL-09 H87Y immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
7u8m | F | E | 0 | D | protein | null | hemagglutinin ha2 subunit | VIRAL PROTEIN/Immune System | 03/08/22 | Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibodies 31.a.83 and FluA-20 | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Zhu, X., Wilson, I.A. | 5.39 | X-RAY DIFFRACTION | 0.342 | 0.304 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6tcs | A | a | 0 | null | null | null | null | IMMUNE SYSTEM | 11/06/19 | Crystal structure of the omalizumab scFv | HOMO SAPIENS | homo sapiens | null | null | Mitropoulou, A.N., Ceska, T., Beavil, A.J., Henry, A.J., McDonnell, J.M., Sutton, B.J., Davies, A.M. | 2.3 | X-RAY DIFFRACTION | 0.206 | 0.178 | true | true | unknown | unknown | unknown | null | null | null | null | null |
1ikf | H | L | 0 | C | peptide | null | cyclosporin a | IMMUNE SYSTEM/IMMUNOSUPPRESSANT | 12/09/93 | A CONFORMATION OF CYCLOSPORIN A IN AQUEOUS ENVIRONMENT REVEALED BY THE X-RAY STRUCTURE OF A CYCLOSPORIN-FAB COMPLEX | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | tolypocladium inflatum | Vix, O., Altschuh, D., Rees, B., Thierry, J.-C. | 2.5 | X-RAY DIFFRACTION | unknown | 0.164 | false | true | IGHV5 | IGKV10 | Kappa | null | null | null | null | null |
6ada | E | F | 0 | B | protein | null | h(+)/cl(-) exchange transporter clca | TRANSPORT PROTEIN | 07/31/18 | Crystal structure of the E148D mutant CLC-ec1 in 200mM bromide | ESCHERICHIA COLI (STRAIN K12); MUS MUSCULUS | mus musculus | mus musculus | escherichia coli (strain k12) | Lim, H.-H., Park, K. | 3.153 | X-RAY DIFFRACTION | 0.290 | 0.231 | false | false | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
6cue | 3 | 4 | 0 | 1 | protein | null | envelope glycoprotein gp41 | VIRAL PROTEIN | 03/26/18 | Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody vFP7.04 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | human immunodeficiency virus 1 | Acharya, P., Carragher, B., Potter, C.S., Kwong, P.D. | 4.0 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7kkl | B | null | 0 | A | protein | null | sars-cov-2 spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/27/20 | SARS-CoV-2 Spike in complex with neutralizing nanobody mNb6 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SYNTHETIC CONSTRUCT | synthetic construct | null | severe acute respiratory syndrome coronavirus2 | Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., ... | 2.85 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
5u7m | D | E | 0 | B | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/Immune system | 12/12/16 | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer bound to small molecule HIV-1 entry inhibitor BMS-378806 in Complex with Human Antibodies PGT122 and 35O22 at 3.8 A. | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Pancera, M., Lai, Y.-T., Kwong, P.D. | 3.025 | X-RAY DIFFRACTION | 0.289 | 0.245 | false | true | unknown | unknown | unknown | 0 | -9.201455 | Unknown | null | TBD |
6phc | C | D | 0 | E | protein | null | 25 kda ookinete surface antigen | IMMUNE SYSTEM | 06/25/19 | Pfs25 in complex with the human transmission blocking antibody 2544 | PLASMODIUM FALCIPARUM; HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium falciparum | McLeod, B.R., Julien, J.P. | 2.9 | X-RAY DIFFRACTION | 0.238 | 0.200 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
6vy6 | H | L | 0 | A | protein | null | receptor binding protein | VIRAL PROTEIN/IMMUNE SYSTEM | 02/25/20 | Crystal structure of Hendra receptor binding protein head domain in complex with human neutralizing antibody HENV-26 | HENDRA HENIPAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | hendra henipavirus | Dong, J., Crowe, J.E. | 2.6 | X-RAY DIFFRACTION | 0.247 | 0.197 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
7ek0 | H | L | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 04/03/21 | Complex Structure of antibody BD-503 and RBD-N501Y of COVID-19 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Xu, H., Wang, B., Zhao, T.N., Su, X.D. | 2.7 | X-RAY DIFFRACTION | 0.266 | 0.214 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5f1k | C | null | 0 | A | protein | null | adp-ribosyl cyclase/cyclic adp-ribose hydrolase 1 | HYDROLASE/IMMUNE SYSTEM | 11/30/15 | human CD38 in complex with nanobody MU1053 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Zhang, H., Hao, Q. | 2.3 | X-RAY DIFFRACTION | 0.231 | 0.198 | false | true | IGHV1 | null | null | null | null | null | null | null |
5lz0 | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 09/29/16 | Llama nanobody PorM_01 | LAMA GLAMA | lama glama | null | null | Duhoo, Y., Leone, P., Roussel, A. | 1.6 | X-RAY DIFFRACTION | 0.232 | 0.203 | false | true | IGHV1 | null | null | null | null | null | null | null |
4w6y | B | null | 0 | A | protein | null | f18 fimbrial adhesin ac | CELL ADHESION | 08/21/14 | Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF9 | ESCHERICHIA COLI DH5[ALPHA]; LAMA GLAMA | lama glama | null | escherichia coli dh5[alpha] | Moonens, K., De Kerpel, M., Coddens, A., Cox, E., Pardon, E., Remaut, H., De Greve, H. | 1.57 | X-RAY DIFFRACTION | 0.226 | 0.195 | false | true | IGHV1 | null | null | 0 | -12.00718 | SPR | null | TBD |
4evn | A | B | 0 | null | null | null | null | immune system | 04/26/12 | Crystal Structure of Fab CR6261 (somatic heavy chain with germline-reverted light chain) | HOMO SAPIENS | homo sapiens | homo sapiens | null | Whittle, J.R.R. | 2.851 | X-RAY DIFFRACTION | 0.293 | 0.230 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7n9c | D | null | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/17/21 | Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB95 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Sun, D., Zhang, C., Shi, Y. | 3.71 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7f12 | B | b | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/ANTIVIRAL PROTEIN | 06/07/21 | A SARS-CoV-2 neutralizing antibody | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | null | severe acute respiratory syndrome coronavirus2 | Zhang, G., Li, X., Guo, Y., Wang, Y., Yuan, S. | 3.15 | X-RAY DIFFRACTION | 0.245 | 0.195 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7e8m | H | L | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/02/21 | Crystal structure of SARS-CoV-2 antibody P2C-1F11 with mutated RBD | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X.Q., Zhang, L.Q., Ge, J.W., Wang, R.K., Lan, J. | 2.09 | X-RAY DIFFRACTION | 0.199 | 0.169 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
3jbg | 7 | null | 0 | null | null | null | null | VIRUS/IMMUNE SYSTEM | 08/26/15 | Complex of poliovirus with VHH PVSS21E | CAMELUS DROMEDARIUS; HUMAN POLIOVIRUS 1 MAHONEY | camelus dromedarius | null | null | Strauss, M., Schotte, L., Thys, B., Filman, D.J., Hogle, J.M. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4f33 | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 05/08/12 | Crystal Structure of therapeutic antibody MORAb-009 | MUS MUSCULUS | null | null | null | Xia, D., Ma, J., Tang, W.K., Esser, L. | 1.749 | X-RAY DIFFRACTION | 0.234 | 0.208 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
4kkl | E | F | 0 | B | protein | null | h(+)/cl(-) exchange transporter clca | tranport protein, membrane protein | 05/06/13 | Structure of the E148A mutant of CLC-ec1 delta NC construct in 100mM fluoride | MUS MUSCULUS; ESCHERICHIA COLI | mus musculus | mus musculus | escherichia coli | Stockbridge, R.B., Lim, H.-H., Miller, C. | 2.85 | X-RAY DIFFRACTION | 0.290 | 0.248 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
1aif | B | A | 0 | null | null | null | null | IMMUNOGLOBULIN | 11/14/94 | ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A) FAB FROM MOUSE | MUS MUSCULUS | mus musculus | mus musculus | null | Ban, N., Escobar, C., Hasel, K., Day, J., Greenwood, A., McPherson, A. | 2.9 | X-RAY DIFFRACTION | unknown | 0.220 | false | false | IGHV6 | IGKV4 | Kappa | null | null | null | null | null |
6oq8 | C | null | 0 | B | protein | null | toxin b | TOXIN | 04/25/19 | Structure of the GTD domain of Clostridium difficile toxin B in complex with VHH 7F | CLOSTRIDIOIDES DIFFICILE; CAMELIDAE | camelidae | null | clostridioides difficile | Chen, P., Lam, K., Jin, R. | 2.2 | X-RAY DIFFRACTION | 0.220 | 0.197 | false | true | IGHV1 | null | null | null | null | null | null | null |
7rmh | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN/MEMBRANE PROTEIN | 07/27/21 | Substance P bound to active human neurokinin 1 receptor in complex with miniGs399 | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | Harris, J.A., Faust, B., Gondin, A.B., Daemgen, M.A., Suomivuori, C.M., Veldhuis, N.A., Cheng, Y., Dror, R.O., Thal, D., Manglik, A. | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
5o8f | K | null | 0 | A | protein | null | gamma-aminobutyric acid receptor subunit beta-3,gamma-aminobutyric acid receptor subunit alpha-5,gamma-aminobutyric acid receptor subunit alpha-5 | MEMBRANE PROTEIN | 06/13/17 | Structure of a chimaeric beta3-alpha5 GABAA receptor in complex with nanobody Nb25 and pregnanolone | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Miller, P.S., Scott, S., Masiulis, S., De Colibus, L., Pardon, E., Steyaert, J., Aricescu, A.R. | 3.2 | X-RAY DIFFRACTION | 0.242 | 0.232 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ewb | E | F | 0 | A | protein | null | vp1 | VIRAL PROTEIN | 11/03/17 | Crystal structure of GII.4 UNSW 2012 P domain in complex with Fab 10E9 | NOROVIRUS HU/GII.4/SYDNEY/NSW0514/2012/AU; MUS MUSCULUS | mus musculus | mus musculus | norovirus hu/gii.4/sydney/nsw0514/2012/au | Koromyslova, A.D., Hansman, G.S. | 2.78 | X-RAY DIFFRACTION | 0.222 | 0.186 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6z3k | E | F | 0 | null | null | null | null | IMMUNE SYSTEM | 05/20/20 | Structure of protective antibody 38-1-10A Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Zhou, D., Fry, E.E., Ren, J., Stuart, D.I. | 2.7 | X-RAY DIFFRACTION | 0.234 | 0.188 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6e9k | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 08/01/18 | The crystal structure of bovine ultralong antibody BOV-5 | BOS TAURUS | bos taurus | bos taurus | null | Dong, J., Crowe, J.E. | 2.193 | X-RAY DIFFRACTION | 0.264 | 0.204 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7mfu | F | null | 0 | D | protein | null | spike protein s1 | VIRAL PROTEIN | 04/11/21 | Crystal structure of synthetic nanobody complexes with SARS-CoV-2 receptor binding domain | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SYNTHETIC CONSTRUCT | synthetic construct | null | severe acute respiratory syndrome coronavirus2 | Jiang, J., Ahmad, J., Natarajan, K., Boyd, L.F., Margulies, D.H. | 1.7 | X-RAY DIFFRACTION | 0.215 | 0.181 | false | true | IGHV1 | null | null | null | null | null | null | null |
7phq | F | null | 0 | null | null | null | null | MEMBRANE PROTEIN | 08/18/21 | Structure of homo-dimeric Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM | SYNTHETIC CONSTRUCT; STAPHYLOCOCCUS CAPITIS; LAMA GLAMA | lama glama | null | null | Bloch, J.S., Mukherjee, S., Kowal, J., Kossiakoff, A.A., Locher, K.P. | 8.45 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4ffw | H | L | 0 | A | protein | null | dipeptidyl peptidase 4 | HYDROLASE/Immune System, INHIBITOR | 06/01/12 | Crystal Structure of Dipeptidyl Peptidase IV (DPP4, DPP-IV, CD26) in Complex with Fab + sitagliptin | RATTUS NORVEGICUS; MUS MUSCULUS | mus musculus | mus musculus | rattus norvegicus | Wang, Z., Sudom, A., Walker, N.P., Min, X. | 2.9 | X-RAY DIFFRACTION | 0.311 | 0.287 | false | false | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
5e0q | A | null | 0 | B | protein | null | nuclear pore complex protein nup98-nup96 | TRANSPORT PROTEIN | 09/29/15 | Crystal structure of the Nup98 C-terminal domain bound to nanobody TP377 | VICUGNA PACOS; XENOPUS TROPICALIS | vicugna pacos | null | xenopus tropicalis | Pleiner, T., Trakhanov, S., Goerlich, D. | 1.9 | X-RAY DIFFRACTION | 0.196 | 0.167 | false | true | IGHV1 | null | null | null | null | null | null | null |
7my2 | H | null | 0 | E | protein | null | spike glycoprotein | IMMUNE SYSTEM/VIRAL PROTEIN | 05/20/21 | CryoEM structure of neutralizing nanobody Nb30 in complex with SARS-CoV2 spike | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | null | severe acute respiratory syndrome coronavirus2 | Xu, K., Kwong, P.D. | 2.65 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
2dd8 | H | L | 0 | S | protein | null | spike glycoprotein | IMMUNE SYSTEM/VIRAL PROTEIN | 01/24/06 | Crystal Structure of SARS-CoV Spike Receptor-Binding Domain Complexed with Neutralizing Antibody | HOMO SAPIENS; SARS CORONAVIRUS | homo sapiens | homo sapiens | sars coronavirus | Prabakaran, P., Gan, J.H., Feng, Y., Zhu, Z.Y., Xiao, X.D., Ji, X., Dimitrov, D.S. | 2.3 | X-RAY DIFFRACTION | 0.261 | 0.199 | false | true | IGHV1 | IGLV3 | Lambda | 0 | -10.5 | SPR | 25 | 16597622 |
3qcv | H | L | 0 | H | Hapten | 18L | (2R)-2-HYDROXY-3-(PHOSPHONOOXY)PROPYL (9Z,12Z)-OCTADECA-9,12-DIENOATE | IMMUNE SYSTEM | 01/17/11 | Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (18:2) | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Fleming, J.K., Wojciak, J.M., Campbell, M.-A., Huxford, T. | 2.51 | X-RAY DIFFRACTION | 0.266 | 0.215 | false | true | IGHV5 | IGKV2D | Kappa | null | null | null | null | null |
6emj | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 10/02/17 | FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery | HOMO SAPIENS | homo sapiens | homo sapiens | null | Benz, J., Weigand, S., Dengl, S., Schlothauer, T., Auer, J., Ehler, A., Kettenberger, H., Lorenz, S., Hirschheydt, T., Georges, G. | 2.3 | X-RAY DIFFRACTION | 0.211 | 0.165 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6vbq | H | L | 0 | P | peptide | null | envelope glycoprotein gp160 | IMMUNE SYSTEM/Viral Protein | 12/19/19 | Crystal structure of anti-HIV-1 antibody DH822 bound to gp120 V2 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Janus, B.M., Ofek, G. | 2.116 | X-RAY DIFFRACTION | 0.211 | 0.181 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
7mep | M | J | 0 | C | F | protein | protein | NA | NA | bg505 sosipv5.2(7s) - gp120 | bg505 sosipv5.2(7s) - gp120 | VIRAL PROTEIN | 04/07/21 | BG505 SOSIP.v5.2(7S) in complex with the monoclonal antibodies Rh.33172 mAb.1 and RM19R | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS | macaca mulatta | macaca mulatta | human immunodeficiency virus | human immunodeficiency virus | Antanasijevic, A., Ward, A.B. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
3oay | M | K | 0 | M | Hapten | BDF | BETA-D-FRUCTOPYRANOSE | IMMUNE SYSTEM | 08/05/10 | A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Doores, K.J., Fulton, Z., Hong, V., Patel, M.K., Scanlan, C.N., Wormald, M.R., Finn, M.G., Burton, D.R., Wilson, I.A., Davis, B.G | 1.95 | X-RAY DIFFRACTION | 0.223 | 0.182 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7cwu | O | S | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 08/31/20 | SARS-CoV-2 spike proteins trimer in complex with P17 and FC05 Fabs cocktail | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Wang, N. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6ymq | B | b | 0 | I | protein | null | triggering receptor expressed on myeloid cells 2 | IMMUNE SYSTEM | 04/09/20 | TREM2 extracellular domain (19-131) in complex with single-chain variable 4 (scFv-4) | HOMO SAPIENS | homo sapiens | null | homo sapiens | Szykowska, A., Preger, C., Scacioc, A., Mukhopadhyay, S.M.M., McKinley, G., Graslund, S., Wigren, E., Persson, H., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Di Daniel, E., Davis, J.B., Burgess-Brown, N., Bullock, A. | 3.07 | X-RAY DIFFRACTION | 0.288 | 0.274 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7c2l | H | L | 0 | A | protein | null | spike glycoprotein | MEMBRANE PROTEIN/IMMUNE SYSTEM | 05/08/20 | S protein of SARS-CoV-2 in complex bound with 4A8 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yan, R.H., Zhang, Y.Y., Guo, Y.Y., Li, Y.N., Xia, L., Zhou, Q. | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
5u65 | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 12/07/16 | Camel Nanobody VHH-5 | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Stanfield, R.L., Wilson, I.A. | 2.3 | X-RAY DIFFRACTION | 0.261 | 0.201 | false | true | IGHV1 | null | null | null | null | null | null | null |
6meh | H | L | 0 | C | protein | null | e2 glycoprotein | IMMUNE SYSTEM | 09/06/18 | Broadly neutralizing antibodies against HCV use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design | HEPACIVIRUS C; HOMO SAPIENS | homo sapiens | homo sapiens | hepacivirus c | Flyak, A.I., Bjorkman, P.J. | 1.99 | X-RAY DIFFRACTION | 0.230 | 0.186 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7a6o | B | null | 0 | A | protein | null | unknown | BLOOD CLOTTING | 08/25/20 | Crystal Structure of the Complex of the Recombinant Von Willebrand Factor AIM-A1 domain and VHH81 at 2.1 Angstrom resolution | HOMO SAPIENS; LAMA GLAMA | null | null | null | Brown, A.K., Emsley, J. | 2.1 | X-RAY DIFFRACTION | 0.256 | 0.195 | false | false | IGHV3 | null | null | null | null | null | null | null |
5m2i | K | null | 0 | D | protein | null | tumor necrosis factor | CYTOKINE | 10/13/16 | Structure of human Tumor Necrosis Factor (TNF) in complex with the Llama VHH1 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Cambillau, C., Spinelli, S., Desmyter, A., de Haard, H. | 2.15 | X-RAY DIFFRACTION | 0.238 | 0.207 | false | true | IGHV1 | null | null | 0 | -12.643277 | SPR | null | TBD |
7ec5 | E | F | 0 | B | A | C | protein | protein | protein | NA | NA | NA | genome polyprotein | capsid protein vp1 | capsid protein vp3 | VIRUS | 03/11/21 | EV-D68 in complex with 8F12 Fab | MUS MUSCULUS; HUMAN ENTEROVIRUS D68 | mus musculus | mus musculus | human enterovirus d68 | human enterovirus d68 | human enterovirus d68 | Xu, C., Cong, Y. | 2.89 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6o1f | H | L | 0 | A | I | protein | protein | NA | NA | tryptase alpha/beta-1 | trypsin inhibitor a | IMMUNE SYSTEM/HYDROLASE | 02/19/19 | Complex between soybean trypsin inhibitor beta1-tryptase and a humanized fab | HOMO SAPIENS; GLYCINE MAX | homo sapiens | homo sapiens | homo sapiens | glycine max | Ultsch, M.H., Yi, T. | 2.15 | X-RAY DIFFRACTION | 0.233 | 0.190 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5vr9 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/10/17 | CH1/Ckappa Fab based on Matuzumab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Hendle, J. | 2.15 | X-RAY DIFFRACTION | 0.244 | 0.210 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6eyo | I | M | 0 | B | protein | null | immunoglobulin heavy constant epsilon | IMMUNE SYSTEM | 11/13/17 | Structure of extended IgE-Fc in complex with two anti-IgE Fabs | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Chen, J.B., Ramadani, F., Pang, M.O.Y., Beavil, R.L., Holdom, M.D., Mitropoulou, A.N., Beavil, A.J., Gould, H.J., Chang, T.W., Sutton, B.J., McDonnell, J.M., Davies, A.M. | 3.7 | X-RAY DIFFRACTION | 0.288 | 0.247 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -14.596007 | SPR | null | TBD |
7n4j | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/04/21 | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2173. | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Sankhala, R.S., Joyce, M.G. | 2.207 | X-RAY DIFFRACTION | 0.207 | 0.172 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
6vmk | S | R | 0 | T | protein | null | fab y49r light chain | HYDROLASE/IMMUNE SYSTEM | 01/28/20 | Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wu, P., Harris, S.F., Eigenbrot, C. | 3.01 | X-RAY DIFFRACTION | 0.215 | 0.174 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
2ajs | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/02/05 | Crystal structure of cocaine catalytic antibody 7A1 Fab' in complex with heptaethylene glycol | MUS MUSCULUS | mus musculus | mus musculus | null | Zhu, X., Wilson, I.A. | 1.7 | X-RAY DIFFRACTION | 0.233 | 0.209 | false | false | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
7k7r | B | A | 0 | C | peptide | null | ebna1 peptide aa386-405 | IMMUNE SYSTEM | 09/23/20 | EBNA1 peptide AA386-405 with Fab MS39p2w174 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human gammaherpesvirus 4 | Lanz, T.V., Robinson, W.H., Jude, K.M. | 2.5 | X-RAY DIFFRACTION | 0.252 | 0.211 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
6nf5 | E | F | 0 | C | protein | null | hiv-1 env bg505 md64 n332-gt5 sosip gp120 | VIRAL PROTEIN/immune system | 12/18/18 | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; MACACA MULATTA | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ozorowski, G., Torres, J.L., Steichen, J.M., Schief, W.R., Ward, A.B. | 3.71 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
3upc | G | null | 0 | null | null | null | null | IMMUNE SYSTEM | 11/17/11 | A general strategy for the generation of human antibody variable domains with increased aggregation resistance | HOMO SAPIENS | homo sapiens | null | null | Dudgeon, K., Rouet, R., Kokmeijer, I., Langley, D.B., Christ, D. | 2.8 | X-RAY DIFFRACTION | 0.247 | 0.209 | false | true | IGHV3 | null | null | null | null | null | null | null |
3gkw | H | L | 0 | null | null | null | null | IMMUNE SYSTEM, ANTITUMOR PROTEIN | 03/11/09 | Crystal structure of the Fab fragment of Nimotuzumab. An anti-epidermal growth factor receptor antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Talavera, A., Friemann, R., Martinez-Fleites, C., Moreno, E., Krengel, U. | 2.5 | X-RAY DIFFRACTION | 0.284 | 0.214 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
2gki | A | a | 0 | null | null | null | null | IMMUNE SYSTEM | 04/02/06 | Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity | MUS MUSCULUS | mus musculus | null | null | Kim, Y.R., Kim, J.S., Lee, S.H., Lee, W.R., Sohn, J.N., Chung, Y.C., Shim, H.K., Lee, S.C., Kwon, M.H., Kim, Y.S. | 2.88 | X-RAY DIFFRACTION | 0.242 | 0.212 | true | true | unknown | unknown | unknown | null | null | null | null | null |
2gfb | N | M | 0 | null | null | null | null | IMMUNOGLOBULIN | 07/07/94 | CRYSTAL STRUCTURE OF A CATALYTIC FAB HAVING ESTERASE-LIKE ACTIVITY | MUS MUSCULUS | mus musculus | mus musculus | null | Golinelli-Pimpaneau, B., Knossow, M. | 3.0 | X-RAY DIFFRACTION | unknown | 0.213 | false | false | IGHV5 | IGKV9 | Kappa | null | null | null | null | null |
6zh9 | F | null | 0 | E | protein | null | unknown | ANTIVIRAL PROTEIN | 06/21/20 | Ternary complex CR3022 H11-H4 and RBD (SARS-CoV-2) | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | null | null | null | Naismith, J.H., Mikolajek, H., Le Bas, A. | 3.31 | X-RAY DIFFRACTION | 0.305 | 0.261 | false | false | IGHV1 | null | null | null | null | null | null | null |
4oaw | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 01/06/14 | Fab structure of anti-HIV gp120 V2 mAb 2158 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Spurrier, B.R., Kong, X.P. | 2.8 | X-RAY DIFFRACTION | 0.254 | 0.182 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5tgb | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 09/27/16 | Structure of chimeric 02-CB Fab, a VRC01-like germline antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pancera, M. | 2.741 | X-RAY DIFFRACTION | 0.286 | 0.249 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7rd9 | H | L | 0 | C | peptide | null | circumsporozoite protein | IMMUNE SYSTEM | 07/09/21 | Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.159 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium falciparum | Xu, K., Kwong, P.D. | 1.91 | X-RAY DIFFRACTION | 0.233 | 0.186 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
7zwi | E | F | 0 | D | protein | null | gametocyte surface protein p45/48 | CELL ADHESION | 05/19/22 | Pfs48/45 C-terminal domain bound to fab fragment of monoclonal antibody 32F3 | Mus musculus; Plasmodium falciparum | mus musculus | mus musculus | plasmodium falciparum | Ko, K.T., Lennartz, F.L., Higgins, M.K. | 1.9 | X-RAY DIFFRACTION | 0.217 | 0.189 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6n5e | H | I | 0 | C | protein | null | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 11/21/18 | Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope | INFLUENZA A VIRUS; MUS MUSCULUS | influenza a virus | mus musculus | influenza a virus | Bajic, G., Schmidt, A.G. | 3.0 | X-RAY DIFFRACTION | 0.287 | 0.250 | false | true | IGHV5 | IGLV1 | Lambda | null | null | null | null | null |
7beh | H | L | 0 | E | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 12/23/20 | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-316 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Zhao, Y., Ren, J., Stuart, D. | 2.3 | X-RAY DIFFRACTION | 0.230 | 0.213 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
3ncy | Q | W | 0 | C | D | protein | protein | NA | NA | adic | adic | TRANSPORT PROTEIN | 06/06/10 | X-ray crystal structure of an arginine agmatine antiporter (AdiC) in complex with a Fab fragment | SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; MUS MUSCULUS | mus musculus | mus musculus | salmonella enterica subsp. enterica serovartyphimurium | salmonella enterica subsp. enterica serovartyphimurium | Fang, Y., Jayaram, H., Shane, T., Komalkova-Partensky, L., Wu, F., Williams, C., Xiong, Y., Miller, C. | 3.2 | X-RAY DIFFRACTION | 0.312 | 0.282 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
5k9q | J | K | 0 | F | A | protein | protein | NA | NA | hemagglutinin ha2 | hemagglutinin ha1 | IMMUNE SYSTEM | 06/01/16 | Crystal structure of multidonor HV1-18-class broadly neutralizing Influenza A antibody 16.a.26 in complex with A/Hong Kong/1-4-MA21-1/1968 (H3N2) Hemagglutinin | INFLUENZA A VIRUS; INFLUENZA A VIRUS (STRAIN A/HONG KONG/1/1968 H3N2); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (strain a/hong kong/1/1968h3n2) | influenza a virus | Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D. | 2.503 | X-RAY DIFFRACTION | 0.218 | 0.182 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
2f5a | H | L | 0 | null | null | null | null | IMMUNOGLOBULIN | 04/08/99 | CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bryson, S., Julien, J.P., Hynes, R.C., Pai, E.F. | 2.05 | X-RAY DIFFRACTION | 0.270 | 0.235 | false | false | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
6xli | C | D | 0 | F | peptide | null | tau phosphopeptide (ac-sr(pt)pslp(pt)pptre-oh) | IMMUNE SYSTEM | 06/28/20 | CRYSTAL STRUCTURE OF ANTI-TAU ANTIBODY PT3 Fab+pT212/pT217-TAU PEPTIDE | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Malia, T.J., Teplyakov, A., Luo, J. | 2.0 | X-RAY DIFFRACTION | 0.213 | 0.186 | false | true | IGHV5 | IGKV14 | Kappa | null | null | null | null | null |
4npy | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/22/13 | Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Julien, J.-P., Diwanji, D.C., Wilson, I.A. | 1.796 | X-RAY DIFFRACTION | 0.220 | 0.182 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
6mpg | m | n | 0 | V | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN | 10/06/18 | Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Kwong, P.D. | 3.2 | ELECTRON MICROSCOPY | null | null | false | false | unknown | unknown | unknown | null | null | null | null | null |
2kh2 | B | b | 73 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
5vkh | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | IMMUNE SYSTEM/TRANSPORT PROTEIN | 04/21/17 | Closed conformation of KcsA Y82A-F103A mutant | STREPTOMYCES LIVIDANS; MUS MUSCULUS | mus musculus | mus musculus | streptomyces lividans | Cuello, L.G., Perozo, E., Cortes, D.M. | 2.25 | X-RAY DIFFRACTION | 0.203 | 0.174 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
4y5y | A | B | 0 | C | protein | null | erythropoietin receptor | protein binding/immune system | 02/12/15 | Diabody 330 complex with EpoR | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Moraga, I., Guo, F., Ozkan, E., Jude, K.M., Garcia, K.C. | 2.85 | X-RAY DIFFRACTION | 0.241 | 0.221 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
7lbg | H | G | 0 | A | protein | null | envelope glycoprotein h | VIRAL PROTEIN/Immune System | 01/07/21 | CryoEM structure of the HCMV Trimer gHgLgO in complex with human Transforming growth factor beta receptor type 3 and neutralizing fabs 13H11 and MSL-109 | HUMAN CYTOMEGALOVIRUS (STRAIN MERLIN); HUMAN CYTOMEGALOVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | human cytomegalovirus (strain merlin) | Kschonsak, M., Rouge, L., Arthur, C.P., Hoangdung, H., Patel, N., Kim, I., Johnson, M., Kraft, E., Rohou, A.L., Gill, A., Martinez-Martin, N., Payandeh, J., Ciferri, C. | 2.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
4n1e | null | D | 0 | J | protein | null | lysozyme c | Immune system/Hydrolase | 10/04/13 | Structural evidence for antigen receptor evolution | HOMO SAPIENS; GALLUS GALLUS | null | homo sapiens | gallus gallus | Langley, D.B., Rouet, R., Stock, D., Christ, D. | 2.23 | X-RAY DIFFRACTION | 0.265 | 0.223 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
3o6k | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/29/10 | Crystal structure of anti-Tat HIV Fab'11H6H1 | MUS MUSCULUS | mus musculus | mus musculus | null | Serriere, J., Gouet, P., Guillon, C. | 2.0 | X-RAY DIFFRACTION | 0.246 | 0.199 | false | false | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7p79 | B | null | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 07/19/21 | SARS-CoV-2 spike protein in complex with sybodyb#15 in a 1up/1up-out/1down conformation. | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SYNTHETIC CONSTRUCT | synthetic construct | null | severe acute respiratory syndrome coronavirus2 | Walter, J.D., Hutter, C.A.J., Garaeva, A.A., Scherer, M., Zimmermann, I., Wyss, M., Rheinberger, J., Ruedin, Y., Earp, J.C., Egloff, P., Sorgenfrei, M., Huerlimann, L.M., Gonda, I., Meier, G., Remm, S., Thavarasah, S., Zimmer, G., Slotboom, D.J., Paulino, C., Plattet, P., Seeger, M.A. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3j8z | H | L | 0 | E | protein | null | l1 | VIRUS/IMMUNE SYSTEM | 11/20/14 | Cryo-EM reconstruction of quasi-HPV16 complex with H16.1A Fab | HUMAN PAPILLOMAVIRUS TYPE 16; MUS MUSCULUS | mus musculus | mus musculus | human papillomavirus type 16 | Guan, J., Hafenstein, S. | 14 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7lqv | W | X | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 02/15/21 | Cryo-EM structure of NTD-directed neutralizing antibody 4-8 Fab in complex with SARS-CoV-2 S2P spike | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Gorman, J., Rapp, M., Kwong, P.D., Shapiro, L. | 3.25 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
6ii8 | G | I | 0 | A | protein | null | hemagglutinin | IMMUNE SYSTEM | 10/03/18 | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4B-18 | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Jiang, H.H., Shi, Y., Qi, J., Gao, G.F. | 3.32 | X-RAY DIFFRACTION | 0.251 | 0.203 | false | true | IGHV3 | IGLV6 | Lambda | 0 | -8.74946 | SPR | null | TBD |
6nm6 | H | L | 0 | G | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM | 01/10/19 | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to N6 FR3-03 scFv in Complex with Crystallization Chaperones 3H109L Fab and 35O22 scFv at 3.2 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lai, Y.-T., Kwong, P.D. | 2.739 | X-RAY DIFFRACTION | 0.288 | 0.240 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
5mwn | F | null | 0 | C | protein | null | type vi secretion protein | TRANSPORT PROTEIN | 01/18/17 | Structure of the EAEC T6SS component TssK N-terminal domain in complex with llama nanobodies nbK18 and nbK27 | LAMA GLAMA; ESCHERICHIA COLI | lama glama | null | escherichia coli | Cambillau, C., Nguyen, V.S., Spinelli, S., Legrand, P. | 2.2 | X-RAY DIFFRACTION | 0.220 | 0.199 | false | true | IGHV1 | null | null | null | null | null | null | null |
6nfc | H | L | 0 | A | protein | null | hiv-1 env bg505 md64 n332-gt5 sosip gp120 | VIRAL PROTEIN | 12/19/18 | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP42 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ozorowski, G., Torres, J.L., Ward, A.B. | 3.43 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
5uty | H | L | 0 | G | protein | null | hiv-1 bg505 strain env gp120 | VIRAL PROTEIN/immune system | 02/15/17 | Crystal Structure of a Stabilized DS-SOSIP.mut4 BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, N300M, N302M, T320L in Complex with Human Antibodies PGT122 and 35O22 at 4.1 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Xu, K., Chuang, G.-Y., Pancera, M., Kwong, P.D. | 3.412 | X-RAY DIFFRACTION | 0.288 | 0.241 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
7bub | H | L | 0 | A | C | protein | protein | NA | NA | dengue virus serotype2 e protein | dengue virus serotype2 e protein | VIRUS | 04/06/20 | Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 6.5 | HOMO SAPIENS; DENGUE VIRUS 2 | homo sapiens | homo sapiens | dengue virus 2 | dengue virus 2 | Zhang, S., Chew, S.V., Lim, X.N., Ng, T.S., Kostyuchenko, V.A., Lok, S.M. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5hvg | D | null | 0 | C | protein | null | carboxypeptidase b2 | hydrolase/hydrolase inhibitor | 01/28/16 | Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with an Inhibitory Nanobody (VHH-a204) | VICUGNA PACOS; HOMO SAPIENS | vicugna pacos | null | homo sapiens | Zhou, X., Weeks, S.D., Strelkov, S.V., Declerck, P.J. | 3.05 | X-RAY DIFFRACTION | 0.212 | 0.179 | false | true | IGHV1 | null | null | 0 | -12.551945 | SPR | null | TBD |
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