pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7kq7 | H | L | 0 | B | protein | null | interleukin-21 receptor | PROTEIN BINDING/Immune System | 11/13/20 | Crystal structure of IL21R in complex with an antibody Fab fragment | RATTUS NORVEGICUS; HOMO SAPIENS | rattus norvegicus | rattus norvegicus | homo sapiens | Mosyak, L., Svenson, K. | 2.203 | X-RAY DIFFRACTION | 0.240 | 0.215 | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
5umi | A | B | 0 | C | protein | null | toxin a | TOXIN/IMMUNE SYSTEM | 01/27/17 | Clostridium difficile TcdA-CROPs bound to PA50 Fab | CLOSTRIDIOIDES DIFFICILE; HOMO SAPIENS | homo sapiens | homo sapiens | clostridioides difficile | Kroh, H.K., Chandrasekaran, R., Rosenthal, K., Woods, R., Jin, X., Ohi, M.D., Nyborg, A.C., Rainey, G.J., Warrener, P., Spiller, B.W., Lacy, D.B. | 3.23 | X-RAY DIFFRACTION | 0.290 | 0.270 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4yho | H | L | 0 | H | Hapten | 4CC | N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine | IMMUNE SYSTEM | 02/27/15 | Reversal Agent for Dabigatran | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Schiele, F., Nar, H. | 1.82 | X-RAY DIFFRACTION | 0.210 | 0.180 | false | true | IGHV1 | IGKV1 | Kappa | 0 | -14.658431 | Unknown | null | TBD |
6ju0 | J | N | 0 | J | Hapten | TOE | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL | IMMUNE SYSTEM | 04/12/19 | Mouse antibody 3.3 Fab in complex with PEG | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Lee, C.C., Ko, T.P., Lin, L.L., Wang, A.H.J. | 2.601 | X-RAY DIFFRACTION | 0.240 | 0.211 | false | true | IGHV6 | IGKV4 | Kappa | null | null | null | null | null |
6pzh | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/31/19 | Crystal structure of human NA-22 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Zhu, X., Wilson, I.A. | 2.3 | X-RAY DIFFRACTION | 0.236 | 0.193 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
7tm0 | N | O | 0 | A | protein | null | spike glycoprotein | VIRUS | 01/19/22 | SARS-CoV-2 S B.1.1.529 Omicron variant + S309 + S2L20 Global Refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1d6v | H | L | 0 | H | Hapten | HOP | (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL | IMMUNE SYSTEM | 10/15/99 | CONFORMATION EFFECTS IN BIOLOGICAL CATALYSIS INTRODUCED BY OXY-COPE ANTIBODY MATURATION | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | mus musculus, homo sapiens | Mundorff, E.C., Hanson, M.A., Schultz, P.G., Stevens, R.C. | 2.0 | X-RAY DIFFRACTION | 0.264 | 0.224 | false | true | IGHV1 | IGKV14 | Kappa | 0.000001 | -8.422741 | Unknown | null | TBD |
2omb | null | C | 0 | null | null | null | null | Immune system | 01/21/07 | Bence Jones KWR Protein- Immunoglobulin Light Chain Dimer, P3(1)21 Crystal Form | HOMO SAPIENS | null | homo sapiens | null | Makino, D.L., Larson, S.B., McPherson, A. | 2.9 | X-RAY DIFFRACTION | 0.284 | 0.235 | false | false | null | IGLV2 | Lambda | null | null | null | null | null |
4o02 | H | L | 0 | A | protein | null | integrin alpha-v | Protein binding | 12/13/13 | AlphaVBeta3 integrin in complex with monoclonal antibody FAB fragment. | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Mahalingam, B., van Agthoven, J., Xiong, J., Arnaout, M.A. | 3.605 | X-RAY DIFFRACTION, 1 | 0.312 | 0.246 | false | false | IGHV1 | IGKV10 | Kappa | null | null | null | null | null |
7n08 | H | L | 0 | F | peptide | null | hiv-1 gp41 immunodominant region | IMMUNE SYSTEM | 05/25/21 | Crystal structure of the 3D6 antibody fragment bound to the HIV-1 gp41 immunodominant region | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | hiv-1 06tg.ht008 | Cook, J.D., Lee, J.E. | 2.0 | X-RAY DIFFRACTION | 0.203 | 0.165 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7nd5 | H | L | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN, IMMUNE SYSTEM | 01/30/21 | EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-150 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Duyvesteyn, H.M.E., Zhao, Y., Ren, J., Stuart, D. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7cho | H | L | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN | 07/06/20 | Crystal structure of SARS-CoV-2 antibody P5A-1D2 with RBD | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Zhang, L., Ge, J., Wang, R., Zhang, Q. | 2.561 | X-RAY DIFFRACTION | 0.247 | 0.202 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
5h37 | K | L | 0 | B | protein | null | structural protein e | VIRUS/IMMUNE SYSTEM | 10/20/16 | Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 | HOMO SAPIENS; ZIKA VIRUS | homo sapiens | homo sapiens | zika virus | Zhang, S., Kostyuchenko, V., Ng, T.-S., Lim, X.-N., Ooi, J.S.G., Lambert, S., Tan, T.Y., Widman, D., Shi, J., Baric, R.S., Lok, S.-M. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
4qxg | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/20/14 | Antigen binding fragment of an anti IFNAR1 antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Oganesyan, V.Y., Dall'Acqua, W.F. | 2.3 | X-RAY DIFFRACTION | 0.249 | 0.190 | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
7l2e | G | J | 0 | B | protein | null | spike glycoprotein | Viral Protein/IMMUNE SYSTEM | 12/16/20 | Cryo-EM structure of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Cerutti, G., Shapiro, L. | 2.97 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
3dvn | H | L | 0 | V | U | protein | protein | NA | NA | ubiquitin | ubiquitin d77 | IMMUNE SYSTEM | 07/18/08 | Crystal structure of K63-specific fab Apu2.16 bound to K63-linked di-ubiquitin | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Hymowitz, S.G. | 2.7 | X-RAY DIFFRACTION | 0.268 | 0.220 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -9.59 | SPR | null | 18724939 |
7l0n | M | N | 0 | S | protein | null | spike protein s1 | VIRAL PROTEIN/HYDROLASE | 12/11/20 | Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Snell, G., Czudnochowski, N., Dillen, J., Nix, J.C., Croll, T.I., Corti, D. | 2.78 | X-RAY DIFFRACTION | 0.325 | 0.290 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6vi1 | B | A | 0 | N | peptide | null | terminase, large subunit | IMMUNE SYSTEM | 01/11/20 | Structure of Fab4 bound to P22 TerL(1-33) | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | salmonella phage p22 | Cingolani, G., Lokareddy, R., Ko, Y. | 2.4 | X-RAY DIFFRACTION | 0.239 | 0.189 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6tcr | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/06/19 | Crystal structure of the omalizumab Fab Ser81Arg, Gln83Arg and Leu158Pro light chain mutant | HOMO SAPIENS | homo sapiens | homo sapiens | null | Mitropoulou, A.N., Ceska, T., Beavil, A.J., Henry, A.J., McDonnell, J.M., Sutton, B.J., Davies, A.M. | 1.45 | X-RAY DIFFRACTION | 0.184 | 0.166 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6jwc | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 04/19/19 | Mouse antibody 2B5 Fab in complex with PEG | MUS MUSCULUS | mus musculus | mus musculus | null | Lee, C.C., Ko, T.P., Su, Y.C., Lin, L.L., Roffler, S.R., Wang, A.H.J. | 2.297 | X-RAY DIFFRACTION | 0.226 | 0.187 | false | true | IGHV6 | IGKV4 | Kappa | null | null | null | null | null |
5mvg | null | A | 0 | null | null | null | null | IMMUNE SYSTEM | 01/16/17 | Crystal structure of non-amyloidogenic light chain dimer M7 | HOMO SAPIENS | null | homo sapiens | null | Oberti, L., Rognoni, P., Bacarizo, J., Bolognesi, M., Ricagno, S. | 2.2 | X-RAY DIFFRACTION | 0.239 | 0.207 | false | false | null | IGLV3 | Lambda | null | null | null | null | null |
1nc4 | D | C | 0 | D | Hapten | DOF | (S)-2-(4-NITROBENZYL)-1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAACETATE | Immune system | 12/04/02 | Crystal Structure of Monoclonal Antibody 2D12.5 Fab Complexed with Gd-DOTA | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Corneillie, T.M., Fisher, A.J., Meares, C.F. | 2.25 | X-RAY DIFFRACTION | 0.248 | 0.208 | false | false | IGHV2 | IGLV1 | Lambda | null | null | null | null | null |
6uc6 | D | null | 0 | B | protein | null | botulinum neurotoxin type b | HYDROLASE/ANTITOXIN | 09/15/19 | Crystal structure of BoNT/B receptor-binding domain in complex with VHH JLI-H11 | CLOSTRIDIUM BOTULINUM; VICUGNA PACOS | vicugna pacos | null | clostridium botulinum | Lam, K., Jin, R. | 2.32006 | X-RAY DIFFRACTION | 0.222 | 0.170 | false | true | IGHV1 | null | null | null | null | null | null | null |
6y90 | C | D | 0 | B | protein | null | b-lymphocyte antigen cd20 | MEMBRANE PROTEIN | 03/06/20 | Structure of full-length CD20 in complex with Rituximab Fab | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Kumar, A., Reyes, N. | 3.69 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
7mfa | U | V | 0 | null | null | null | null | IMMUNE SYSTEM | 04/08/21 | Crystal structure of antibody 10E8v4-P100fA+P100gA Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Kwon, Y.D., Kwong, P.D. | 2.4 | X-RAY DIFFRACTION | 0.286 | 0.238 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
5ye3 | B | A | 0 | C | peptide | null | di-acetylated histone h4 | NUCLEAR PROTEIN | 09/15/17 | Crystal structure of the complex of di-acetylated histone H4 and 2A7D9 Fab fragment | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Matsuda, T., Ito, T., Wakamori, M., Umehara, T. | 1.7 | X-RAY DIFFRACTION | 0.195 | 0.166 | false | true | IGHV9 | IGKV19 | Kappa | null | null | null | null | null |
6ztf | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/20/20 | Crystal Structure of the anti-human P-Cadherin Fab CQY684 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Rondeau, J.M., Lehmann, S. | 1.55 | X-RAY DIFFRACTION | 0.207 | 0.188 | false | true | IGHV6 | IGKV1 | Kappa | null | null | null | null | null |
4qhl | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 05/28/14 | I3.2 (unbound) from CH103 Lineage | HOMO SAPIENS | homo sapiens | homo sapiens | null | Fera, D., Harrison, S.C. | 3.153 | X-RAY DIFFRACTION | 0.281 | 0.237 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
6k41 | H | h | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(o) subunit alpha | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 05/23/19 | cryo-EM structure of alpha2BAR-GoA complex | HOMO SAPIENS; MUS MUSCULUS; BOS TAURUS; ENTEROBACTERIA PHAGE RB59 | mus musculus | null | homo sapiens | mus musculus | Daopeng, Y., Zhongmin, L., Hongwei, W., Brian, K. | 2.9 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
5l0q | C | B | 0 | A | protein | null | disintegrin and metalloproteinase domain-containing protein10 | HYDROLASE/IMMUNE SYSTEM | 07/28/16 | Crystal structure of the complex between ADAM10 D+C domain and a conformation specific mAb 8C7. | HOMO SAPIENS; BOS TAURUS | homo sapiens | homo sapiens | bos taurus | Xu, K., Saha, N., Nikolov, D.B. | 2.759 | X-RAY DIFFRACTION | 0.251 | 0.203 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
7ahu | B | A | 0 | E | F | protein | protein | NA | NA | coagulation factor x | coagulation factor x | BLOOD CLOTTING | 09/25/20 | Anti-FX Fab of mim8 in complex with human FXa | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Johansson, E. | 2.6 | X-RAY DIFFRACTION | 0.263 | 0.203 | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
5tud | F | E | 0 | D | protein | null | 5-hydroxytryptamine receptor 2b,soluble cytochrome b562chimera | SIGNALING PROTEIN | 11/05/16 | Structural Insights into the Extracellular Recognition of the Human Serotonin 2B Receptor by an Antibody | HOMO SAPIENS; ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens, escherichia coli | Ishchenko, A., Wacker, D., Kapoor, M., Zhang, A., Han, G.W., Basu, S., Boutet, S., James, D., Wang, D., Weierstall, U., Liu, W., Katritch, V., Stevens, R.C., Cherezov, V. | 3.0 | X-RAY DIFFRACTION | 0.247 | 0.227 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6mph | X | Z | 0 | A | protein | null | pgt122 light chain | VIRAL PROTEIN | 10/06/18 | Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Kwong, P.D. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
5i17 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 02/05/16 | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV3-20 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G. | 3.3 | X-RAY DIFFRACTION | 0.247 | 0.202 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
2qtj | C | O | 1 | null | null | null | null | IMMUNE SYSTEM | 08/02/07 | Solution structure of human dimeric immunoglobulin A | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Furtado, P.B., Almogren, A., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7zmv | K | null | 0 | C | protein | null | atp-dependent dna helicase q5 | HYDROLASE | 04/19/22 | Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G5-006 | Homo sapiens; Lama glama | lama glama | null | homo sapiens | Ye, M., Makola, M., Newman, J.A., Fairhead, M., MacLean, E., Krojer, T., Aitkenhead, H., Bountra, C., Gileadi, O., von Delft, F. | 2.002 | X-RAY DIFFRACTION | 0.275 | 0.242 | false | true | IGHV1 | null | null | null | null | null | null | null |
7mzg | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 05/24/21 | SARS-CoV-2 receptor binding domain bound to Fab PDI 42 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Pymm, P., Chan, L.J., Dietrich, M.H., Tan, L.L., Tham, W.H. | 2.0 | X-RAY DIFFRACTION | 0.236 | 0.200 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5t6p | D | C | 0 | E | peptide | null | muc1 peptide fragment | IMMUNE SYSTEM | 09/01/16 | Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Brooks, C.L., Movahedin, M. | 1.97 | X-RAY DIFFRACTION | 0.232 | 0.221 | false | true | IGHV5 | IGKV1 | Kappa | 0.000001 | -8.261204 | Unknown | null | TBD |
7rp0 | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | TRANSPORT PROTEIN | 08/02/21 | Structural Snapshots of Intermediates in the Gating of a K+ Channel | MUS MUSCULUS; STREPTOMYCES LIVIDANS | mus musculus | mus musculus | streptomyces lividans | Reddi, R., Matulef, K., Riederer, E.A., Valiyaveetil, F.I. | 2.48 | X-RAY DIFFRACTION | 0.271 | 0.242 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
4nco | L | K | 0 | I | protein | null | bg505 sosip gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/24/13 | Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Julien, J.-P., Stanfield, R.L., Lyumkis, D., Ward, A.B., Wilson, I.A. | 4.7 | X-RAY DIFFRACTION | 0.389 | 0.375 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
7zfc | A | B | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Beta RBD in complex with nanobody C1, Omi-18 and Omi-31 Fabs | HOMO SAPIENS; LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 3.24 | X-RAY DIFFRACTION | 0.299 | 0.244 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
4aiz | null | D | 0 | null | null | null | null | IMMUNE SYSTEM | 02/15/12 | Crystallographic structure of 3mJL2 from the germinal line lambda 3 | HOMO SAPIENS | null | homo sapiens | null | Villalba, M.I., Luna, O.D., Rudino-Pinera, E., Sanchez, R., Sanchez-Lopez, R., Rojas-Trejo, S., Olamendi-Portugal, T., Fernandez-Velasco, D.A., Becerril, B. | 1.75 | X-RAY DIFFRACTION | 0.2185 | 0.1662 | false | true | null | IGLV3 | Lambda | null | null | null | null | null |
5tfw | H | L | 0 | O | protein | null | 10e8 epitope scaffold t117v2 | IMMUNE SYSTEM | 09/26/16 | Crystal structure of 10E8 Fab light chain mutant2 against the MPER region of the HIV-1 Env, in complex with T117v2 epitope scaffold | SYNTHETIC CONSTRUCT; HOMO SAPIENS | homo sapiens | homo sapiens | synthetic construct | Irimia, A., Wilson, I.A. | 2.168 | X-RAY DIFFRACTION | 0.228 | 0.169 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -14.713586 | SPR | null | TBD |
5m13 | B | null | 0 | null | null | null | null | IMMUNE SYSTEM | 10/07/16 | Synthetic nanobody in complex with MBP | ESCHERICHIA COLI; SYNTHETIC CONSTRUCT | synthetic construct | null | null | Zimmermann, I., Egloff, P., Seeger, M.A. | 1.372 | X-RAY DIFFRACTION | 0.186 | 0.168 | false | true | IGHV1 | null | null | null | null | null | null | null |
5njg | E | F | 0 | A | protein | null | atp-binding cassette sub-family g member 2 | TRANSPORT PROTEIN | 03/28/17 | Structure of an ABC transporter: part of the structure that could be built de novo | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Taylor, N.M.I., Manolaridis, I., Jackson, S.M., Kowal, J., Stahlberg, H., Locher, K.P. | 3.78 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV13 | Kappa | null | null | null | null | null |
4r4n | F | G | 0 | E | protein | null | m48u1 peptide | VIRAL PROTEIN/IMMUNE SYSTEM/INHIBITOR | 08/19/14 | Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Louder, R., Kwong, P.D. | 3.56 | X-RAY DIFFRACTION | 0.328 | 0.296 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
5c0r | H | L | 0 | A | protein | null | hemagglutinin, envelope glycoprotein, fibritin fusionprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/12/15 | Crystal Structure of a Generation 3 Influenza Hemagglutinin Stabilized Stem Complexed with the Broadly Neutralizing Antibody C179 | MUS MUSCULUS; INFLUENZA A VIRUS, HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 GROUP M SUBTYPE B, ENTEROBACTERIA PHAGE T4 | mus musculus | mus musculus | influenza a virus, human immunodeficiency virustype 1 group m subtype b, enterobacteria phage t4 | Boyington, J.C., kwong, P.D., Nabel, G.J., Mascola, J.R. | 3.188 | X-RAY DIFFRACTION | 0.251 | 0.199 | false | true | IGHV7 | IGKV12 | Kappa | null | null | null | null | null |
1uwx | H | L | 0 | P | peptide | null | class 1 outer membrane protein variable region 2 | IMMUNE SYSTEM | 02/12/04 | P1.2 serosubtype antigen derived from N. meningitidis PorA in complex with Fab fragment | STREPTOCOCCUS SP.; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | neisseria meningitidis | Tzitzilonis, C., Prince, S.M., Collins, R.F., Maiden, M.C.J., Feavers, I.M., Derrick, J.P. | 2.2 | X-RAY DIFFRACTION | 0.265 | 0.223 | false | false | IGHV9 | IGKV12 | Kappa | 0.000002 | -7.9 | SPR | null | 16470851 |
6dca | K | O | 0 | S | peptide | null | microtubule-associated protein tau | IMMUNE SYSTEM | 05/04/18 | Fab/epitope complex of mouse monoclonal antibody 6B2 targeting a non-phosphorylated tau epitope. | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Chukwu, J.E., Kong, X.-P. | 2.599 | X-RAY DIFFRACTION | 0.259 | 0.189 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5ja9 | A | null | 0 | C | protein | null | toxin higb-2 | TOXIN | 04/12/16 | Crystal structure of the HigB2 toxin in complex with Nb6 | LAMA GLAMA; VIBRIO CHOLERAE SEROTYPE O1 (STRAIN ATCC 39315 / EL TOR INABA N16961) | lama glama | null | vibrio cholerae serotype o1 (strain atcc 39315/ el tor inaba n16961) | Hadzi, S., Loris, R. | 1.849 | X-RAY DIFFRACTION | 0.241 | 0.195 | false | true | IGHV1 | null | null | null | null | null | null | null |
6w5d | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 03/13/20 | Crystal Structure of Fab RSB1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Harshbarger, W., Chandramouli, S., Malito, M. | 2.0 | X-RAY DIFFRACTION | 0.277 | 0.232 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
4tnv | W | f | 0 | P | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | Transport Protein/immune System | 06/05/14 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab in a non-conducting conformation | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Althoff, T., Hibbs, R.E., Banerjee, S., Gouaux, E. | 3.6 | X-RAY DIFFRACTION | 0.283 | 0.261 | false | false | unknown | unknown | unknown | null | null | null | null | null |
5y9f | R | Q | 0 | D | protein | null | heavy chain of fab fragment of antibody 28f10 | VIRAL PROTEIN/IMMUNE SYSTEM | 08/24/17 | Crystal structure of HPV59 pentamer in complex with the Fab fragment of antibody 28F10 | HUMAN PAPILLOMAVIRUS TYPE 59; MUS MUSCULUS | mus musculus | mus musculus | human papillomavirus type 59 | Li, S.W., Li, Z.H. | 3.35 | X-RAY DIFFRACTION | 0.261 | 0.230 | false | false | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7jtr | H | h | 0 | G | protein | null | maltose/maltodextrin-binding periplasmic protein | SUGAR BINDING PROTEIN/IMMUNE SYSTEM | 08/18/20 | Complex of maltose-binding protein (MBP) with single-chain Fv (scFv) | MUS MUSCULUS; ESCHERICHIA COLI | mus musculus | null | escherichia coli | Loll, P.J. | 2.5 | X-RAY DIFFRACTION | 0.237 | 0.201 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7m6d | A | B | 0 | C | protein | null | spike protein s1 | VIRAL PROTEIN/ANTIVIRAL PROTEIN | 03/25/21 | Structure of the SARS-CoV-2 RBD in complex with neutralizing antibodies BG4-25 and CR3022 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Barnes, C.O., Bjorkman, P.J. | 3.1 | X-RAY DIFFRACTION | 0.259 | 0.219 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
3gm0 | a | A | 0 | A | Hapten | B41 | (2S)-1-(1,3-BENZODIOXOL-5-YL)-N-METHYLPROPAN-2-AMINE | IMMUNE SYSTEM | 03/12/09 | Anti-methamphetamine single chain Fv in complex with MDMA | MUS MUSCULUS | null | mus musculus | mus musculus | Celikel, R., Peterson, E.C., Owens, M., Varughese, K.I. | 2.4 | X-RAY DIFFRACTION | 0.271 | 0.214 | true | true | unknown | unknown | unknown | 0 | -10.599564 | Unknown | null | TBD |
7mw5 | F | G | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 05/15/21 | Structure of the SARS-CoV-2 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody clone 2 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Hu, Y., Xiong, Y. | 3.42 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7phq | H | L | 0 | null | null | null | null | MEMBRANE PROTEIN | 08/18/21 | Structure of homo-dimeric Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM | SYNTHETIC CONSTRUCT; STAPHYLOCOCCUS CAPITIS; LAMA GLAMA | synthetic construct | synthetic construct | null | Bloch, J.S., Mukherjee, S., Kowal, J., Kossiakoff, A.A., Locher, K.P. | 8.45 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6xun | C | D | 0 | G | carbohydrate | NAG | N-ACETYL-D-GLUCOSAMINE | ANTITUMOR PROTEIN | 01/20/20 | Ab 5b1 bound to CA19-9 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Diskin, R., Borenstein-Katz, A. | 2.41 | X-RAY DIFFRACTION | 0.215 | 0.169 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7cwt | L | H | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 08/31/20 | SARS-CoV-2 Spike protein in complex with hb27 and fc05 Fab cocktail | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Cui, Z., Wang, X. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7nfd | D | C | 0 | B | protein | null | atp-binding cassette sub-family g member 2 | MEMBRANE PROTEIN | 02/06/21 | Structure of mitoxantrone-bound ABCG2 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Kowal, J., Locher, K., Ni, D., Stahlberg, H. | 3.51 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV13 | Kappa | null | null | null | null | null |
2jix | H | L | 0 | E | protein | null | erythropoietin receptor | RECEPTOR/IMMUNE SYSTEM | 07/02/07 | Crystal structure of ABT-007 FAB fragment with the soluble domain of EPO receptor | ESCHERICHIA COLI; HOMO SAPIENS | null | null | homo sapiens | Liu, Z., Stoll, V.S., DeVries, P., Jakob, C.G., Xie, N., Simmer, R.L., Lacy, S.E., Egan, D.A., Harlan, J.E., Lesniewski, R.R., Reilly, E.B. | 3.2 | X-RAY DIFFRACTION | 0.323 | 0.257 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -10.26 | SPR | null | 17620453 |
4r7n | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 08/28/14 | Fab C2E3 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Loyau, J., Didelot, G., Malinge, P., Ravn, U., Magistrelli, G., Depoisier, J.F., Kosco-Vilbois, M., Fischer, N., Thore, S., Rousseau, F. | 3.45 | X-RAY DIFFRACTION | 0.280 | 0.236 | false | true | IGHV4 | IGKV6 | Kappa | null | null | null | null | null |
2r0z | H | L | 0 | Q | peptide | null | gripi peptide fragment | IMMUNE SYSTEM | 08/21/07 | PFA1 FAB complexed with GripI peptide fragment | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Gardberg, A.S., Dealwis, C. | 2.096 | X-RAY DIFFRACTION | 0.261 | 0.201 | false | false | IGHV8 | IGKV1 | Kappa | 0.000003 | -7.33 | SPR | 20 | 17895381 |
5v8l | J | N | 0 | A | protein | null | gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/22/17 | BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibodies 3BNC117 and PGT145 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lee, J.H., Ward, A.B. | 4.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
3dur | B | A | 0 | A | carbohydrate | KDO | 3-DEOXY-D-MANNO-OCT-2-ULOSONIC ACID | IMMUNE SYSTEM | 07/17/08 | Crystal structure of SAG173-04 | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Brooks, C.L., Blackler, R.J., Gerstenbruch, S., Kosma, P., Muller-Loennies, S., Brade, H., Evans, S.V. | 1.86 | X-RAY DIFFRACTION | 0.247 | 0.178 | false | true | IGHV7 | IGKV8 | Kappa | null | null | null | null | null |
2kh2 | B | b | 56 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6kr0 | C | c | 0 | null | null | null | null | IMMUNE SYSTEM | 08/20/19 | Crystal structure of HL homo-diabody | HOMO SAPIENS | homo sapiens | null | null | Tanaka, Y. | 2.3 | X-RAY DIFFRACTION | 0.226 | 0.202 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7kml | J | N | 0 | C | protein | null | spike glycoprotein | Viral protein/Immune System | 11/03/20 | cryo-EM structure of SARS-CoV-2 spike in complex with Fab 15033-7, three RBDs bound | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Li, Z., Rini, J.M. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6um5 | C | D | 0 | A | protein | null | ch848 10.17 dt gp120 | VIRAL PROTEIN/immune system | 10/09/19 | Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT Env | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Henderson, R.C., Saunders, K.O., Haynes, B.F. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
6mwx | G | H | 0 | F | protein | null | e2 | VIRUS/IMMUNE SYSTEM | 10/30/18 | CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-69 Antibody | EASTERN EQUINE ENCEPHALITIS VIRUS; MUS MUSCULUS | mus musculus | mus musculus | eastern equine encephalitis virus | Hasan, S.S., Sun, C., Kim, A.S., Watanabe, Y., Chen, C.L., Klose, T., Buda, G., Crispin, M., Diamond, M.S., Klimstra, W.B., Rossmann, M.G. | 8.2 | ELECTRON MICROSCOPY | null | null | false | false | IGHV9 | IGLV1 | Lambda | null | null | null | null | null |
4jzn | I | P | 0 | K | peptide | null | envelope glycoprotein e2 | immune system/viral protein | 04/03/13 | Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-1 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | hepatitis c virus (isolate h) | Krey, T., Rey, F.A. | 2.05 | X-RAY DIFFRACTION | 0.235 | 0.198 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
5esa | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 11/16/15 | Crystal structure of anti-HCV E2 antibody HC84-26 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Gao, M., Mariuzza, R. | 2.6 | X-RAY DIFFRACTION | 0.251 | 0.185 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
7pgb | X | Y | 0 | Z | protein | null | ion transport protein,voltage-gated sodium channel | MEMBRANE PROTEIN | 08/13/21 | NaV_Ae1/Sp1CTD_pore-SAT09 complex | HOMO SAPIENS; ALKALILIMNICOLA EHRLICHII (STRAIN ATCC BAA-1101 / DSM 17681 / MLHE-1); RUEGERIA POMEROYI (STRAIN ATCC 700808 / DSM 15171 / DSS-3) | homo sapiens | homo sapiens | alkalilimnicola ehrlichii (strain atcc baa-1101/ dsm 17681 / mlhe-1), ruegeria pomeroyi (strain atcc 700808 / dsm 15171 / dss-3) | Lolicato, M., Arrigoni, C. | 3.6 | X-RAY DIFFRACTION | 0.232 | 0.207 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4jy5 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/29/13 | Crystal structure of human Fab PGT122, a broadly reactive and potent HIV-1 neutralizing antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Julien, J.-P., Diwanji, D.C., Burton, D.R., Wilson, I.A. | 1.75 | X-RAY DIFFRACTION | 0.242 | 0.198 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
7rxd | H | L | 0 | B | protein | null | maltodextrin-binding protein,immunoglobulin g-bindingprotein a,immunoglobulin g-binding protein g | STRUCTURAL PROTEIN | 08/22/21 | CryoEM structure of RBD domain of COVID-19 in complex with Legobody | ESCHERICHIA COLI; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS SP.; MUS MUSCULUS; VICUGNA PACOS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | mus musculus | mus musculus | escherichia coli, staphylococcus aureus,streptococcus sp. | Wu, X.D., Rapoport, T.A. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
5ggs | C | D | 0 | Y | protein | null | programmed cell death protein 1 | IMMUNE SYSTEM | 06/16/16 | PD-1 in complex with pembrolizumab Fab | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Heo, Y.S. | 1.997 | X-RAY DIFFRACTION | 0.228 | 0.180 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4d9r | H | L | 0 | A | protein | null | complement factor d | HYDROLASE/IMMUNE SYSTEM | 01/11/12 | Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Murray, J.M., Wiesmann, C. | 2.42 | X-RAY DIFFRACTION | 0.251 | 0.213 | false | true | IGHV7 | IGKV1 | Kappa | 0 | -15.549572 | SPR | null | TBD |
5j9p | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | METAL TRANSPORT | 04/10/16 | KcsA in vitro | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | streptomyces lividans | Matulef, K., Valiyaveetil, F.I. | 2.85 | X-RAY DIFFRACTION | 0.266 | 0.217 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
6aj7 | H | L | 0 | C | B | protein | protein | NA | NA | capsid protein vp3 | capsid protein vp2 | VIRUS | 08/27/18 | The structure of Enterovirus D68 mature virion in complex with Fab 15C5 | MUS MUSCULUS; ENTEROVIRUS D68 | mus musculus | mus musculus | enterovirus d68 | enterovirus d68 | Zheng, Q.B., Zhu, R., Xu, L.F., He, M.Z., Yan, X.D., Cheng, T., Li, S.W. | 3.6 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV9 | Kappa | null | null | null | null | null |
7dr4 | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 12/25/20 | Complex of anti-human IL-2 antibody and human IL-2 | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | null | Kim, M.S., Kim, J.E. | 2.49 | X-RAY DIFFRACTION | 0.258 | 0.195 | false | true | IGHV1 | IGKV17 | Kappa | null | null | null | null | null |
7p7a | A | null | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 07/19/21 | SARS-CoV-2 spike protein in complex with sybody#68 in a 2up/1flexible conformation | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SYNTHETIC CONSTRUCT | synthetic construct | null | severe acute respiratory syndrome coronavirus2 | Walter, J.D., Hutter, C.A.J., Garaeva, A.A., Scherer, M., Zimmermann, I., Wyss, M., Rheinberger, J., Ruedin, Y., Earp, J.C., Egloff, P., Sorgenfrei, M., Huerlimann, L.M., Gonda, I., Meier, G., Remm, S., Thavarasah, S., Zimmer, G., Slotboom, D.J., Paulino, C., Plattet, P., Seeger, M.A. | 4.76 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6vca | E | F | 0 | A | protein | null | 5'-nucleotidase, ecto (cd73), isoform cra_a | IMMUNE SYSTEM | 12/20/19 | TB38 complex | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Zhou, Y.F., Lord, D.M. | 3.73 | X-RAY DIFFRACTION | 0.264 | 0.224 | false | true | IGHV3 | IGLV8 | Lambda | null | null | null | null | null |
6xjw | C | D | 0 | B | nucleic-acid | null | self-alkylating ribozyme (58-mer) | RNA/IMMUNE SYSTEM | 06/24/20 | Crystal structure of a self-alkylating ribozyme - alkylated form without biotin moiety | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | aeropyrum pernix | Koirala, D., Piccirilli, J.A. | 1.918 | X-RAY DIFFRACTION | 0.227 | 0.188 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6u51 | A | null | 0 | D | protein | null | nucleoprotein | IMMUNE SYSTEM | 08/26/19 | Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) Complexed with Sudan ebolavirus Nucleoprotein C-terminal Domain 610-738 | LAMA GLAMA; SUDAN EBOLAVIRUS (STRAIN BONIFACE-76) | lama glama | null | sudan ebolavirus (strain boniface-76) | Taylor, A.B., Sherwood, L.J., Hart, P.J., Hayhurst, A. | 2.52 | X-RAY DIFFRACTION | 0.250 | 0.208 | false | true | unknown | unknown | unknown | null | null | null | null | null |
1fj1 | B | A | 0 | F | protein | null | outer surface protein a | IMMUNE SYSTEM | 08/07/00 | LYME DISEASE ANTIGEN OSPA IN COMPLEX WITH NEUTRALIZING ANTIBODY FAB LA-2 | BORRELIA BURGDORFERI; MUS MUSCULUS | mus musculus | mus musculus | borrelia burgdorferi | Ding, W., Lawson, C.L. | 2.68 | X-RAY DIFFRACTION | 0.281 | 0.226 | false | false | IGHV9 | IGKV19 | Kappa | null | null | null | null | null |
1g9e | A | null | 6 | null | null | null | null | IMMUNE SYSTEM | 11/23/00 | SOLUTION STRUCTURE AND RELAXATION MEASUREMENTS OF AN ANTIGEN-FREE HEAVY CHAIN VARIABLE DOMAIN (VHH) FROM LLAMA | LAMA GLAMA | lama glama | null | null | Renisio, J.-G., Perez, J., Czisch, M., Guenneugues, M., Bornet, O., Frenken, L., Cambillau, C., Darbon, H. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3lrh | null | G | 0 | H | peptide | null | huntingtin | IMMUNE SYSTEM | 02/11/10 | Structure of anti-huntingtin VL domain in complex with huntingtin peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | null | homo sapiens | null | Schiefner, A., Chatwell, L., Skerra, A. | 2.6 | X-RAY DIFFRACTION | 0.278 | 0.216 | false | true | null | IGLV1 | Lambda | 0 | -10.022811 | Unknown | null | TBD |
5dur | H | L | 0 | C | protein | null | hemagglutinin | IMMUNE SYSTEM | 09/20/15 | Influenza A virus H5 hemagglutinin globular head in complex with antibody 100F4 | INFLUENZA A VIRUS (A/ANHUI/1/2005(H5N1)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/anhui/1/2005(h5n1)) | Zuo, T., Sun, J., Wang, G., Zhou, P., Wang, X., Zhang, L. | 2.82 | X-RAY DIFFRACTION | 0.257 | 0.208 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
5fuo | H | L | 0 | null | null | null | null | null | 01/28/16 | Extending the half-life of a Fab fragment through generation of a humanised anti-Human Serum Albumin (HSA) Fv domain: an investigation into the correlation between affinity and serum half-life | HOMO SAPIENS | homo sapiens | homo sapiens | null | Adams, R., Ceska, T. | 3.6 | X-RAY DIFFRACTION | 0.2536 | 0.2151 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5bq7 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 05/28/15 | Crystal structure of chikungunya virus-human Fab 5F-10 fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Mangala Prasad, V., Rossmann, M.G. | 2.738 | X-RAY DIFFRACTION | 0.288 | 0.232 | false | true | IGHV7 | IGLV1 | Lambda | null | null | null | null | null |
1bre | null | C | 0 | null | null | null | null | IMMUNOGLOBULIN | 07/19/95 | IMMUNOGLOBULIN LIGHT CHAIN PROTEIN | HOMO SAPIENS | null | homo sapiens | null | Schormann, N., Benson, M.D. | 2.0 | X-RAY DIFFRACTION | 0.337 | 0.218 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
4lmq | E | I | 0 | F | protein | null | stromal cell-derived factor 1 | cell adhesion/immune system | 07/10/13 | Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Zhong, Z., Wang, J., Li, B., Xiang, H., Ultsch, M., Coons, M., Wong, T, Chiang, N.Y., Clark, S., Clark, R., Quintana, L., Gribling, P., Suto, E., Barck, K., Corpuz, R., Yao, J., Takkar, R., Lee, W.P., Damico-Beyer, L.A., Carano, R.D., Adams, C., Kelley, R.F., Wang, W., Ferrara, N. | 2.773 | X-RAY DIFFRACTION | 0.301 | 0.253 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -12.32567 | BLI | null | TBD |
6mpg | 3 | 4 | 0 | A | protein | null | envelope glycoprotein gp41 | VIRAL PROTEIN | 10/06/18 | Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Acharya, P., Kwong, P.D. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
3hae | H | L | 0 | A | C | protein | peptide | NA | NA | hla class i histocompatibility antigen, a-2 alpha chain | nyeso-1 peptide | IMMUNE SYSTEM | 05/01/09 | Rational development of high-affinity T-cell receptor-like antibodies | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | | Stewart-Jones, G., Wadle, A., Hombach, A., Shenderov, E., Held, G., Fischer, E. | 2.9 | X-RAY DIFFRACTION | 0.283 | 0.201 | false | true | IGHV3 | IGLV2 | Lambda | 0 | -10 | SPR | null | 19307587 |
3ezj | B | null | 0 | A | protein | null | general secretion pathway protein gspd | PROTEIN TRANSPORT | 10/22/08 | Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody | ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | escherichia coli | Korotkov, K.V, Pardon, E., Steyaert, J., Hol, W.G. | 2.8 | X-RAY DIFFRACTION | 0.239 | 0.192 | false | true | IGHV1 | null | null | null | null | null | null | null |
6vbp | J | I | 0 | K | peptide | null | envelope glycoprotein gp160 | IMMUNE SYSTEM/Viral Protein | 12/19/19 | Crystal structure of anti-HIV-1 antibody DH815 bound to gp120 V2 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Janus, B.M., Ofek, G. | 2.298 | X-RAY DIFFRACTION | 0.229 | 0.180 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
5t1l | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 08/19/16 | Cetuximab Fab in complex with CQA(Ph)2DLSTRRLKC peptide | MUS MUSCULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Bzymek, K.P., Williams, J.C. | 2.48 | X-RAY DIFFRACTION | 0.204 | 0.158 | false | true | IGHV2 | IGKV5 | Kappa | 0 | -9.031008 | Unknown | null | TBD |
5xwd | H | D | 0 | A | protein | null | epidermal growth factor receptor | SIGNALING PROTEIN | 06/29/17 | Crystal structure of the complex of 059-152-Fv and EGFR-ECD | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Matsuda, T., Ito, T., Shirouzu, M. | 2.894 | X-RAY DIFFRACTION | 0.331 | 0.277 | false | true | IGHV4 | IGLV3 | Lambda | 0 | -11.226567 | SPR | null | TBD |
7q0a | Y | Z | 0 | B | protein | null | spike glycoprotein,spike ectodomain,spike protein s2' | VIRAL PROTEIN | 10/14/21 | SARS-CoV-2 Spike ectodomain with Fab FI3A | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; BAT CORONAVIRUS RP3/2004; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2, bat coronavirus rp3/2004 | Duyvesteyn, H.M.E., Ren, J., Stuart, D.I. | 4.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
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