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10.1016/j.coi.2018.01.001
Control of B-1a cell development by instructive BCR signaling
B-1a cells remain one of the most enigmatic lymphocyte subsets. In this review, we discuss recent advances in our understanding of the development of these cells and their regulation by the transcription factors Bhlhe41 and Arid3a as well as by the RNA-binding protein Lin28b. A large body of literature supports an inst...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1111/febs.12358
The recognition and removal of cellular poly(ADP-ribose) signals
Poly(ADP-ribosyl)ation is involved in the regulation of a variety of cellular pathways, including, but not limited to, transcription, chromatin, DNA damage and other stress signalling. Similar to other tightly regulated post-translational modifications, poly(ADP-ribosyl)ation employs 'writers', 'readers' and 'erasers' ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
W3044841283
New insight on the oxidative degradation in materials used by Piero Gilardi in two second generation Nature Carpets: A micro-invasive spectroscopic approach
Abstract Nature Carpets are installations realized by Piero Gilardi using expanded polyurethane, cut, shaped, and painted with vibrant colors in order to portrait natural sceneries. Their intrinsic mixed media nature often exposes them to fast degradation. While it is well known how Nature Carpets are realized using ex...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
10.1146/annurev-biochem-060614-034411
Natural photoreceptors as a source of fluorescent proteins, biosensors, and optogenetic tools
Genetically encoded optical tools have revolutionized modern biology by allowing detection and control of biological processes with exceptional spatiotemporal precision and sensitivity. Natural photoreceptors provide researchers with a vast source of molecular templates for engineering of fluorescent proteins, biosenso...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1021/acs.analchem.0c00516
Assessing the Onset of Calcium Phosphate Nucleation by Hyperpolarized Real-Time NMR
We report an experimental approach for high-resolution real-time monitoring of transiently formed species occurring during the onset of precipitation of ionic solids from solution. This is made possible by real-time nuclear magnetic resonance (NMR) monitoring using dissolution dynamic nuclear polarization (D-DNP) to am...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1109/IECON.2013.6699304
Reduction Of Dc Link Capacitance For Three Phase Three Wire Shunt Active Power Filters
Three-phase three-wire shunt active power filters (APFs) usually employ very large electrolytic capacitors in the dc-link to mitigate utility side harmonics. These capacitors are however known to be bulky and of short operating lifetime, particularly for systems where high ripple currents exist. This paper presents the...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1063/1.4804429
Storing Magnetic Information In Irmn Mgo Ta Tunnel Junctions Via Field Cooling
In this paper, we demonstrate that in Ta/MgO/IrMn tunneling junctions, containing no ferromagnetic elements, distinct metastable resistance states can be set by field cooling the devices from above the Neel temperature (TN) along different orientations. Variations of the resistance up to 10% are found upon field coolin...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1192/bjo.2018.12
RETRACTED – Mental health in UK Biobank: development, implementation and results from an online questionnaire completed by 157 366 participants
Background UK Biobank is a well-characterised cohort of over 500 000 participants that offers unique opportunities to investigate multiple diseases and risk factors. Aims An online mental health questionnaire completed by UK Biobank participants was expected to expand the potential for research into mental disorders. M...
[ "Neuroscience and Disorders of the Nervous System", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2981774379
Convergent Evolution of Hydrogenosomes from Mitochondria by Gene Transfer and Loss
Abstract Hydrogenosomes are H2-producing mitochondrial homologs found in some anaerobic microbial eukaryotes that provide a rare intracellular niche for H2-utilizing endosymbiotic archaea. Among ciliates, anaerobic and aerobic lineages are interspersed, demonstrating that the switch to an anaerobic lifestyle with hydro...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1038/jid.2013.535
Efficient keratinocyte differentiation strictly depends on JNK-induced soluble factors in fibroblasts
Previous studies demonstrated that fibroblast-derived and JUN-dependent soluble factors have a crucial role on keratinocyte proliferation and differentiation during cutaneous wound healing. Furthermore, mice with a deficiency in Jun N-terminal kinases (JNKs), JNK1 or JNK2, showed impaired skin development and delayed w...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1145/3343507
Typing Messages For Free In Security Protocols
Security properties of cryptographic protocols are typically expressed as reachability or equivalence properties. Secrecy and authentication are examples of reachability properties, while privacy properties such as untraceability, vote secrecy, or anonymity are generally expressed as behavioral equivalence in a process...
[ "Computer Science and Informatics" ]
10.1038/s41467-018-03026-0
Quantum and electrochemical interplays in hydrogenated graphene
The design of electrochemically gated graphene field-effect transistors for detecting charged species in real time, greatly depends on our ability to understand and maintain a low level of electrochemical current. Here, we exploit the interplay between the electrical in-plane transport and the electrochemical activity ...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1088/0067-0049/192/2/19
Seven Year Wilkinson Microwave Anisotropy Probe Wmap Observations Planets And Celestial Calibration Sources
(Abridged) We present WMAP seven-year observations of bright sources which are often used as calibrators at microwave frequencies. Ten objects are studied in five frequency bands (23 - 94 GHz): the outer planets (Mars, Jupiter, Saturn, Uranus and Neptune) and five fixed celestial sources (Cas A, Tau A, Cyg A, 3C274 and...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
714769
Dusting for the Fingerprints of Planet Formation
With close to 2000 detected planets, it is striking that we still do not understand how planets form. Their building blocks form in gas disks around young stars, where colliding dust grains form ever-larger aggregates. But this growth is not without limits: larger particles quickly drift towards the star and collide at...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
321717
SITE-SPECIFIC DNA REPLICATION PERTURBATION AND ITS EFFECTS ON CHROMOSOME SEGREGATION
Challenges to the stable maintenance of the human genome can come from both endogenous and exogenous sources. However, one of the major threats to genome stability occurs during normal DNA metabolism. The genome is particularly susceptible to perturbation during the S-phase of the cell cycle when DNA replication occurs...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing" ]
10.1016/j.molmet.2018.02.014
NAMPT-mediated NAD <sup>+</sup> biosynthesis is indispensable for adipose tissue plasticity and development of obesity
Objective: The ability of adipose tissue to expand and contract in response to fluctuations in nutrient availability is essential for the maintenance of whole-body metabolic homeostasis. Given the nutrient scarcity that mammals faced for millions of years, programs involved in this adipose plasticity were likely evolve...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1039/c7cs00509a
Iminium and enamine catalysis in enantioselective photochemical reactions
The rapidly growing area of iminium and enamine catalysis in enantioselective photochemistry is reviewed, with an emphasis on catalytic modes and reaction types.
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1103/PhysRevLett.118.098002
Small Activity Differences Drive Phase Separation in Active-Passive Polymer Mixtures
Recent theoretical studies found that mixtures of active and passive colloidal particles phase separate but only at very high activity ratio. The high value poses serious obstacles for experimental exploration of this phenomenon. Here we show using simulations that when the active and passive particles are polymers, th...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.7554/eLife.27470
Structure and in situ organisation of the pyrococcus furiosus archaellum machinery
The archaellum is the macromolecular machinery that Archaea use for propulsion or surface adhesion, enabling them to proliferate and invade new territories. The molecular composition of the archaellum and of the motor that drives it appears to be entirely distinct from that of the functionally equivalent bacterial flag...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1107/S1600577514021018
Design And Development Of A Controlled Pressure Temperature Set Up For In Situ Studies Of Solid Gas Processes And Reactions In A Synchrotron X Ray Powder Diffraction Station
A novel set-up has been designed and used for synchrotron radiation X-ray high-resolution powder diffraction (SR-HRPD) in transmission geometry (spinning capillary) for in situ solid–gas reactions and processes in an isobaric and isothermal environment. The pressure and temperature of the sample are controlled from 10−...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
Q3857868
Miglioramento della capacità produttiva in Ecosys Ltd.
Ecosys Ltd. è stata fondata nel 2011 con la principale attività di produzione di pannelli di parquet in legno non montati. Nel corso degli anni, l'azienda si è affermata sul mercato bulgaro come partner leale e corretto. Il prerequisito principale per questo è il controllo continuo del processo produttivo, così come il...
[ "Products and Processes Engineering" ]
10.1007/s13524-018-0759-3
Same-Sex Parents and Children’s School Progress: An Association That Disappeared Over Time
Research is divided as to whether children living in same-sex parent families achieve different outcomes compared with their peers. In this article, we improve on earlier estimates of such differences and subsequently study whether and why the association between parental union sex composition and children’s school pro...
[ "The Social World and Its Interactions", "Human Mobility, Environment, and Space" ]
772635
Children's Palliative care Outcome Scale
Person-centred care is a core health value of modern health care. The overarching aim of C-POS (Children's Palliative care Outcome Scale) is to develop and validate a person-centred outcome measure for children, young people (CYP) and their families affected by life-limiting & life-threatening conditions (LLLTC). Inter...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "The Social World and Its Interactions" ]
10.1002/smll.201400360
Surface microfluidic patterning and transporting organic small molecules
A microfluidic method is developed to pattern organic small molecules directly in air. When heated to above its melting point, a powder melts into liquid drops which propagate along the pattern area. The method can further be applied to transport other dye molecules, to create multicolored patterns in one step. The flu...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
10.1007/978-3-642-39742-4_31
Applying Search In An Automatic Contract Based Testing Tool
Automated random testing has been shown to be effective at finding faults in a variety of contexts and is deployed in several testing frameworks. AutoTest is one such framework, targeting programs written in Eiffel, an object-oriented language natively supporting executable pre- and postconditions; these respectively s...
[ "Computer Science and Informatics" ]
176739
Recognition and enrichment of archival documents
The overall objective of READ is to implement a Virtual Research Environment where archivists, humanities scholars, computer scientists and volunteers are collaborating with the ultimate goal of boosting research, innovation, development and usage of cutting edge technology for the automated recognition, transcription,...
[ "The Study of the Human Past", "Computer Science and Informatics", "Texts and Concepts" ]
10.1016/j.jde.2020.06.042
Reaction-diffusion systems with initial data of low regularity
Models issued from ecology, chemical reactions and several other application fields lead to semi-linear parabolic equations with super-linear growth. Even if, in general, blow-up can occur, these models share the property that mass control is essential. In many circumstances, it is known that this L1 control is enough ...
[ "Mathematics" ]
10.1111/spc3.12265
The Intention–Behavior Gap
Bitter personal experience and meta-analysis converge on the conclusion that people do not always do the things that they intend to do. This paper synthesizes research on intention–behavior relations to address questions such as: How big is the intention–behavior gap? When are intentions more or less likely to get tran...
[ "The Human Mind and Its Complexity", "The Social World and Its Interactions" ]
10.1038/srep29109
Positron spectroscopy of point defects in the skyrmion-lattice compound MnSi
Outstanding crystalline perfection is a key requirement for the formation of new forms of electronic order in a vast number of widely different materials. Whereas excellent sample quality represents a standard claim in the literature, there are, quite generally, no reliable microscopic probes to establish the nature an...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
W92784938
Etudes des mécanismes cellulaires impliqués dans la signalisation calcique lors de l'exposition à des contaminants environnementaux : les hydrocarbures aromatiques polycycliques (HAPs)
Polycyclic aromatic hydrocarbons (PAHs), such as benzo(a)pyrene (B(a)P), constitute a major family of widely-distributed environmental contaminants known to promote various deleterious effects towards human health, including the development of cancers and cardiovascular pathologies. Most of these effects have been link...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Environmental Biology, Ecology and Evolution" ]
IB 2006003335 W
EVAPORATION PANELS FOR THE TREATING OF SEWAGE AND DEVICE AND METHOD FOR THE MANUFACTURING THEREOF
A device for the manufacturing of evaporation panels (1) by drying, comprising feeding means (9) for net portions (21, 22, 23, 24) and it is characterized in that it comprises a first (3) and a second (4) plurality of supporting members, arranged alternated therebetween and being apt to receive alternatively as rest th...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1051/0004-6361/201116760
Spin Orbit Inclinations Of The Exoplanetary Systems Hat P 8B Hat P 9B Hat P 16B And Hat P 23B
We report the measurement of the spin-orbit angle of the extra-solar planets HAT-P-8 b, HAT-P-9 b, HAT-P-16 b, and HAT-P-23 b, based on spectroscopic observations performed at the Observatoire de Haute-Provence with the SOPHIE spectrograph on the 1. 93-m telescope. Radial velocity measurements of the Rossiter-McLaughli...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
10.1109/TSUSC.2018.2809574
Hpc Cooling A Flexible Modeling Tool For Effective Design And Management
Complex computing platforms such as High Performance Computers and Data Centers are critical systems from the energy sustainability viewpoint, due to their high computational power and demanding thermal stability specifications. In this context, cooling is a crucial component to operate such systems efficiently. Adavan...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1039/c8cc10254f
Electrodeposition of indium from non-aqueous electrolytes
Indium(iii) is electrodeposited from organic electrolytes, in which indium(i) occurs as an intermediate species, and disproportionates to indium(iii) and indium(0) in the form of nanoparticles.
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
759006
Dissecting the role of Translational Regulation in Tumorigenesis
The control of translation is a key determinant of protein abundance, which in turn defines cellular states. The impact of translational regulation may be even greater during the transition from homeostasis to malignancy, as revealed by the surprisingly low correlations between mRNA and protein levels in human cancer d...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Cell Biology, Development, Stem Cells and Regeneration", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W1041015481
Experimental Cinema and the Crystals of Time: Matthias Müller's Visual Poems
Few artistic oeuvres exemplify the myriad facets of avant-garde filmmaking more comprehensively than the work of Matthias Muller.1 The reason, as critics and theorists of Mullers work have pointed out, is Mullers profound cinephilia.2 At once facilitating and representing the return to a scene that has lastingly struct...
[ "Texts and Concepts", "Studies of Cultures and Arts" ]
10.1017/cjlj.2018.4
The People’s Right to Know and State Secrecy
Among the classic arguments which advocates of open government use to fight government secrecy is the appeal to a “people’s right to know. ” I argue that the employment of this idea as a conceptual weapon against state secrecy misfires. I consider two prominent arguments commonly invoked to support the people’s right t...
[ "Institutions, Governance and Legal Systems", "The Social World and Its Interactions" ]
10.1016/j.celrep.2015.12.101
Nac1 Coordinates a Sub-network of Pluripotency Factors to Regulate Embryonic Stem Cell Differentiation
Pluripotent cells give rise to distinct cell types during development and are regulated by often self-reinforcing molecular networks. How such networks allow cells to differentiate is less well understood. Here, we use integrative methods to show that external signals induce reorganization of the mouse embryonic stem c...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1371/journal.pone.0103226
Increased drought impacts on temperate rainforests from Southern South America: Results of a process-based, dynamic forest model
Increased droughts due to regional shifts in temperature and rainfall regimes are likely to affect forests in temperate regions in the coming decades. To assess their consequences for forest dynamics, we need predictive tools that couple hydrologic processes, soil moisture dynamics and plant productivity. Here, we deve...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
10.1039/c3cc49220f
Tuning porosity and activity of microporous polymer network organocatalysts by co-polymerisation
Microporous polymer networks based on binaphthyl phosphoric acids are suitable heterogeneous asymmetric organocatalysts. Herein we show that the porous characteristics of such networks can be fine-tuned by co-polymerisation. This enables us to investigate the influence of the surface area and porosity in microporous ne...
[ "Synthetic Chemistry and Materials", "Physical and Analytical Chemical Sciences" ]
W1988679633
Polymorphism in the Serotonin Receptor 2a (HTR2A) Gene as Possible Predisposal Factor for Aggressive Traits
Aggressive manifestations and their consequences are a major issue of mankind, highlighting the need for understanding the contributory factors. Still, aggression-related genetic analyses have so far mainly been conducted on small population subsets such as individuals suffering from a certain psychiatric disorder or a...
[ "Neuroscience and Disorders of the Nervous System", "Integrative Biology: from Genes and Genomes to Systems", "The Social World and Its Interactions" ]
10.1088/1367-2630/16/1/013005
Stochastic Multi Channel Lock In Detection
High-precision measurements benefit from lock-in detection of small signals. Here we discuss the extension of lock-in detection to many channels, using mutually orthogonal modulation waveforms, and show how the choice of waveforms affects the information content of the signal. We also consider how well the detection sc...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
3743078
Not another history of platonism. the role of aristotle's criticisms of plato in the development of ancient platonism
The conventional historiography of ancient Platonism follows patterns that ultimately go back to Antiquity itself. While these traditional doxographical accounts are not per se inaccurate, they do overlook continuities across different phases of this thousand-year history as well as some unexpected discontinuities. The...
[ "Texts and Concepts", "The Study of the Human Past" ]
10.1007/978-3-319-72050-0_12
Parallel Search With No Coordination
We consider a parallel version of a classical Bayesian search problem. k agents are looking for a treasure that is placed in one of the boxes indexed by \(\mathbb {N}^+\) according to a known distribution p. The aim is to minimize the expected time until the first agent finds it. Searchers run in parallel where at eac...
[ "Computer Science and Informatics", "Mathematics" ]
10.1038/s43016-020-0060-7
Local food crop production can fulfil demand for less than one-third of the population
The distance between the origin and end-point of food supply chains, and the ‘localness’ of food systems, are key considerations of many narratives associated with sustainability. Yet, information on the minimum distance to food crops is still scarce at the global level. Using an optimization model based on ‘foodsheds’...
[ "Earth System Science", "Human Mobility, Environment, and Space" ]
10.1007/JHEP03(2012)055
Towards A Precise Lattice Determination Of The Leading Hadronic Contribution To G 2 _Mu
We report on our computation of the leading hadronic contribution to the anomalous magnetic moment of the muon using two dynamical flavours of non-perturbatively O(a) improved Wilson fermions. The strange quark is introduced in the quenched approximation. Partially twisted boundary conditions are applied to improve the...
[ "Fundamental Constituents of Matter" ]
US 2014/0049113 W
FURNITURE ARTICLE WITH CONCEALED STORAGE AND REMOVABLE PANELS
A modular furniture system composed from reconfigurable interlocking panels using corresponding slot and tab elements is disclosed. The ready-to-assemble furniture system includes a complementary arrangement of non-interlocking interior panels that become secured into position through the means of interlocking exterior...
[ "Products and Processes Engineering" ]
10.1186/1741-7007-8-54
Stepwise Mechanism For Transcription Fidelity
Transcription is the first step of gene expression and is characterized by a high fidelity of RNA synthesis. During transcription, the RNA polymerase active centre discriminates against not just non-complementary ribo NTP substrates but also against complementary 2'- and 3'-deoxy NTPs. A flexible domain of the RNA poly...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1038/msb.2013.13
Increasing population growth by asymmetric segregation of a limiting resource during cell division
We report that when budding yeast are transferred to low-metal environment, they adopt a proliferation pattern in which division is restricted to the subpopulation of mother cells which were born in rich conditions, before the shift. Mother cells continue to divide multiple times following the shift, generating at each...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1016/j.aop.2018.10.007
Gross–Neveu–Wilson model and correlated symmetry-protected topological phases
We show that a Wilson-type discretization of the Gross–Neveu model, a fermionic [Formula presented]-flavor quantum field theory displaying asymptotic freedom and chiral symmetry breaking, can serve as a playground to explore correlated symmetry-protected phases of matter using techniques borrowed from high-energy physi...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
10.1039/c7dt03360e
Towards the continuous production of Pt-based heterogeneous catalysts using microfluidic systems
The continuous production of Pt-based heterogeneous catalysts based on ultra-small (<2 nm) noble metal nanoparticles deposited on mesoporous ordered silica and their catalytic activity in VOC abatement are here reported. Commercially available micromixers can be easily interfaced to create a multistage platform which a...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Products and Processes Engineering", "Materials Engineering" ]
10.1007/JHEP01(2016)101
High Scale Inflation And The Tensor Tilt
In this paper, we explore a novel observational signature of gravitational corrections during slow-roll inflation. We study the coupling of the inflaton field to higher-curvature tensors in models with a minimal breaking of conformal symmetry. In that case, the most general correction to the tensor two-point function i...
[ "Universe Sciences", "Fundamental Constituents of Matter" ]
10.14814/phy2.12376
Genetic and phenotypic differentiation of an andean intermediate altitude population
Highland populations living permanently under hypobaric hypoxia have been subject of extensive research because of the relevance of their physiological adaptations for the understanding of human health and disease. In this context, what is considered high altitude is a matter of interpretation and while the adaptive pr...
[ "Physiology in Health, Disease and Ageing", "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution" ]
3731340
Integrating energy systems and supply chain optimisation for sustainable development: decentralised, energy-leveraging transformation of african development (deltadev)
This project has three core objectives: (1) It aims to place energy systems design within the context of broader sustainable development (SD). Many of the UN’s 17 Sustainable Development Goals (SDGs) are known to be closely linked to energy. This project is the first to translate this nexus into a comprehensive multi-o...
[ "Products and Processes Engineering", "Earth System Science", "Human Mobility, Environment, and Space" ]
10.30687/axon/2532-6848/2020/01/003
List of Men of the Erechtheis Tribe Killed in Battle
This Athenian casualty list of the Erechtheis tribe, c. 460-459 BCE, is an important source for our understanding of the Athenian military effort in the Eastern Mediterranean in the central decades of the 5th century. While it can be safely dated and contextualized on the basis of Thucydides, the inscription highlight...
[ "The Study of the Human Past", "Texts and Concepts" ]
10.1016/j.susc.2016.06.004
STM study of the preparation of clean Ta(110) and the subsequent growth of two-dimensional Fe islands
This report deals with the preparation of a clean Ta(110) surface, investigated by means of scanning tunneling microscopy/spectroscopy as well as by low-energy electron diffraction and Auger electron spectroscopy. The surface initially exhibits a surface reconstruction induced by oxygen contamination. This reconstructi...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1186/s13058-014-0421-y
The dynamic range of circulating tumor DNA in metastatic breast cancer
Introduction: The management of metastatic breast cancer needs improvement. As clinical evaluation is not very accurate in determining the progression of disease, the analysis of circulating tumor DNA (ctDNA) has evolved to a promising noninvasive marker of disease evolution. Indeed, ctDNA was reported to represent a h...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1051/0004-6361/201321523
Planck 2013 Results Xxix Planck Catalogue Of Sunyaev Zeldovich Sources
We describe the all-sky Planck catalogue of clusters and cluster candidates derived from Sunyaev--Zeldovich (SZ) effect detections using the first 15. 5 months of Planck satellite observations. The catalogue contains 1227 entries, making it over six times the size of the Planck Early SZ (ESZ) sample and the largest SZ-...
[ "Universe Sciences" ]
10.1161/CIRCRESAHA.111.247866
Assessing Cell And Organ Senescence Biomarkers
A major goal in cancer and aging research is to discriminate the biochemical modifications that happen locally that could account for the healthiness or malignancy of tissues. Senescence is one general antiproliferative cellular process that acts as a strong barrier for cancer progression, playing a crucial role in agi...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing" ]
10.1186/1471-2202-13-48
Increasing Levels Of Wild Type Creb Up Regulates Several Activity Regulated Inhibitor Of Death Aid Genes And Promotes Neuronal Survival
CREB (cAMP-response element binding protein) is the prototypical signal-regulated transcription factor. In neurons, it is the target of the synaptic activity-induced nuclear calcium-calcium/calmodulin dependent protein kinase (CaMK) IV signaling pathway that controls the expression of genes important for acquired neuro...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
865227
Distributional Macroeconomics in the Long and Short Run
A key development in the “dismal science” has been the incorporation of explicit heterogeneity into models of the macroeconomy. As a result of taking micro data seriously, these theories study macroeconomic questions in terms of distributions of microeconomic variables like income or wealth rather than just aggregates....
[ "Individuals, Markets and Organisations" ]
771527
Foundations and Tools for Client-Side Web Security
The constantly increasing number of attacks on web applications shows how their rapid development has not been accompanied by adequate security foundations and demonstrates the lack of solid security enforcement tools. Indeed, web applications expose a gigantic attack surface, which hinders a rigorous understanding an...
[ "Computer Science and Informatics" ]
interreg_1528
GREen Startup Support
The need to promote a shift towards a low-carbon economy represents many business opportunities. The Small Business Act highlighted that the EU and Member States should enable SMEs to exploit these opportunities. There are many good practice examples which build the capacity of green and blue companies, but unfortunat...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems", "Human Mobility, Environment, and Space" ]
850496
Bismuth Redox Catalysis for Sustainable Organic Synthesis
Homogeneous catalysis based on transition metals has become an indispensable strategy in the development of efficient methodologies for organic synthesis, finding application in a wide variety of processes across the chemical sciences. Inspired by the wealth of reactivity in this area, we present a proposal that depart...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
220508
Play.Care – revolution in early detection and therapy of autism spectrum disorders (asd).
Autism is a serious developmental disability. Children with autism, also known as autism spectrum disorder (ASD), have social, communication and language problems. Prevalence estimates are alarming, with 1 in very 68 children being diagnosed with ASD in Europe. There is no cure for ASD. However, for many children, ASD ...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Neuroscience and Disorders of the Nervous System" ]
W2069988087
Fire Control Emergency Rescue Resources Allocation Based on Calamities and Accidents Risk Evaluation
In order to solve the unreasonable fire control emergency rescue resources allocation based on local government's administrative level and improve the efficiency of the use of fire control emergency rescue resources, 9175 alarm receiving and summoning of Yunnan Fire Force of China in 2012 is analyzed by national fire s...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1007/s00214-016-1867-z
Spectroscopic fingerprints of DNA/RNA pyrimidine nucleobases in third-order nonlinear electronic spectra
Accurate ab initio modeling of spectroscopic signals in nonlinear electronic spectra, such as bidimensional (2D) spectra, requires the computation of the electronic transitions induced by the incoming pump/probe pulses, resulting in a challenging calculation of many electronic excited states. A protocol is thus require...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
US 2013/0073706 W
GRADIENT-BASED SINGLE WELL SAGD RANGING SYSTEM
A tool, method and system for ranging between two wellbores. The target wellbore includes a conductive member disposed within a portion of the target wellbore. An investigative wellbore includes an electromagnetic gradiometer positioned within the wellbore, as well as emitter electrode and return electrode spaced apart...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1038/nature19069
Defining the clonal dynamics leading to mouse skin tumour initiation
The changes in cell dynamics after oncogenic mutation that lead to the development of tumours are currently unknown. Here, using skin epidermis as a model, we assessed the effect of oncogenic hedgehog signalling in distinct cell populations and their capacity to induce basal cell carcinoma, the most frequent cancer in ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
10.1007/JHEP07(2012)162
A Gapless Hard Wall Magnetic Catalysis In Bulk And Boundary
We study various aspects of fermions and their chiral condensates, both in the bulk of AdS4 spacetime and in the dual boundary theory. For the most part, we focus on a geometry with an infra-red hard wall. We show that, contrary to common lore, there exist boundary conditions in which the hard wall gives rise to a disc...
[ "Fundamental Constituents of Matter", "Condensed Matter Physics", "Mathematics" ]
10.1126/science.aao1887
A high-coverage Neandertal genome from Vindija Cave in Croatia
To date, the only Neandertal genome that has been sequenced to high quality is from an individual found in Southern Siberia. We sequenced the genome of a female Neandertal from ~50,000 years ago from Vindija Cave, Croatia, to ~30-fold genomic coverage. She carried 1. 6 differences per 10,000 base pairs between the two ...
[ "Integrative Biology: from Genes and Genomes to Systems", "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]
787516
Study of the Planetary Human-Environment Relationship: The Rise of Global Environmental Governance
SPHERE is a historical study of humanity’s relation to planetary conditions and constraints and how it has become understood as a governance issue. The key argument is that Global Environmental Governance (GEG), which has arisen in response to this issue, is inseparable from the rise of a planetary Earth systems scienc...
[ "The Study of the Human Past", "Institutions, Governance and Legal Systems", "Human Mobility, Environment, and Space" ]
10.1016/j.jmateco.2019.07.012
Learning from ambiguous and misspecified models
We model inter-temporal ambiguity as the scenario in which a Bayesian learner holds more than one prior distribution over a set of models and provide sufficient conditions for ambiguity to fade away because of learning. Our conditions apply to most learning environments: iid and non-iid model-classes, well-specified an...
[ "Mathematics", "Computer Science and Informatics" ]
10.1080/17588928.2010.497585
How Consciousness Will Change Our View On Neuroscience
Abstract Victor Lamme proposed that the study of consciousness should not be based on introspection. Nevertheless, Lamme understands consciousness as a subjective phenomenon, and introspection as the way in which we acquire knowledge about consciousness. This makes the task to find introspective-free methods to study c...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
W1492726771
High torque density magnetically-geared switched flux permanent magnet machines
Due to the high price of rare-earth magnets, it is pertinent to develop high torque density permanent magnet (PM) machines with reduced magnet volume, which is the main purpose of this paper. This paper proposes novel high torque density magnetically-geared switched flux permanent magnet machines in which the stator is...
[ "Systems and Communication Engineering", "Materials Engineering" ]
10.1063/1.4801528
Systematic Study Of Near Infrared Intersubband Absorption Of Polar And Semipolar Gan Aln Quantum Wells
We report on the observation of intersubband absorption in GaN/AlN quantum well superlattices grown on (112¯2)-oriented GaN. The absorption is tuned in the 1. 5–4. 5 μm wavelength range by adjusting the well thickness. The semipolar samples are compared with polar samples with identical well thickness grown during the ...
[ "Condensed Matter Physics", "Materials Engineering", "Physical and Analytical Chemical Sciences" ]
884945
Europe'S transformation: where people matter
The project will organise the presidency event (conference) “Europe’s Transfomation: Where People Matter” in Vienna, Austria, November 2018. It encompasses the operational and strategic work required to host this event, including Innovation and Content Management (e.g. collaboration with stakeholders to jointly desi...
[ "Institutions, Governance and Legal Systems", "The Social World and Its Interactions" ]
10.1039/C8SM01288A
Nanoliter Deposition On Star Shaped Hydrophilic Superhydrophobic Patterned Surfaces
Nanoliter sized droplet deposition has gained increasing importance in many biomedical, chemical, and microfluidic applications and in materials synthesis. In this paper, we report a simple method for rapid and high-throughput deposition of nanoliter-sized droplets by dragging a larger droplet on star-shaped hydrophili...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering", "Condensed Matter Physics" ]
EP 2012054171 W
PRODUCTION AND USE OF CYANOGUANIDINE AND CYANAMIDE
The present invention is concerned with a method of producing a composition comprising cyanoguanidine, the method comprising (a) using a source of energy to react a metal oxide with a source of carbon to produce a finely divided metal carbide at an elevated temperature and immediately reacting the hot finely divided me...
[ "Products and Processes Engineering", "Synthetic Chemistry and Materials", "Physical and Analytical Chemical Sciences" ]
10.1007/978-3-030-31423-1_5
Explaining Data With Formal Concept Analysis
We give a brief introduction into Formal Concept Analysis, an approach to explaining data by means of lattice theory.
[ "Computer Science and Informatics", "Mathematics" ]
10.1021/acs.accounts.6b00232
Nonempirical Double-Hybrid Functionals: An Effective Tool for Chemists
ConspectusDensity functional theory (DFT) emerged in the last two decades as the most reliable tool for the description and prediction of properties of molecular systems and extended materials, coupling in an unprecedented way high accuracy and reasonable computational cost. This success rests also on the development o...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1145/3313276.3316318
Oblivious Dimension Reduction For K Means Beyond Subspaces And The Johnson Lindenstrauss Lemma
We show that for n points in d-dimensional Euclidean space, a data oblivious random projection of the columns onto m∈ O((logk+loglogn)e−6log1/e) dimensions is sufficient to approximate the cost of all k-means clusterings up to a multiplicative (1±e) factor. The previous-best upper bounds on m are O(logn· e−2) given by ...
[ "Mathematics", "Computer Science and Informatics" ]
10.1016/j.bandl.2014.07.006
Phoneme-free prosodic representations are involved in pre-lexical and lexical neurobiological mechanisms underlying spoken word processing
Recently we reported that spoken stressed and unstressed primes differently modulate Event Related Potentials (ERPs) of spoken initially stressed targets. ERP stress priming was independent of prime-target phoneme overlap. Here we test whether phoneme-free ERP stress priming involves the lexicon. We used German target ...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1111/j.1365-2958.2011.07947.x
An orphan sensor kinase controls quinolone signal production via MexT in Pseudomonas aeruginosa
Pseudomonas aeruginosa employs both N-acylhomoserine lactone and 2-alkyl-4(1H)-quinolone (AQ)-mediated interbacterial signalling for the orchestration of a genome-wide gene regulatory network. Despite the many advances that have been made in understanding the target genes of quorum sensing regulation, little is known o...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution" ]
10.1016/j.cmet.2016.03.009
Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan
Summary Increased production of reactive oxygen species (ROS) has long been considered a cause of aging. However, recent studies have implicated ROS as essential secondary messengers. Here we show that the site of ROS production significantly contributes to their apparent dual nature. We report that ROS increase with a...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
US 2009/0000457 W
APPARATUS AND METHOD FOR IMAGING IONIZING RADIATION
A system and method are disclosed for capturing a radiographic or autoradiographic image of an object, in which a support member is provided to receive the object in an immobilized state; a phosphor screen is provided to transduce ionizing radiation from the source to visible light; film or a digital capture device is ...
[ "Systems and Communication Engineering", "Physical and Analytical Chemical Sciences" ]
10.1007/978-3-030-31784-3_30
Model Checking Data Flows In Concurrent Network Updates
We present a model checking approach for the verification of data flow correctness in networks during concurrent updates of the network configuration. This verification problem is of great importance for software-defined networking (SDN), where errors can lead to packet loss, black holes, and security violations. Our a...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1021/nl4002475
Binary superlattices from colloidal nanocrystals and giant polyoxometalate clusters
We report a new kind of long-range ordered binary superlattices comprising atomically defined inorganic clusters and colloidally synthesized nanocrystals. In a model system, we combined surfactant-encapsulated, nearly spherical giant polyoxometalate clusters containing 2. 9 nm polyoxomolybdate or 2. 5 nm polyoxovanadom...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics", "Materials Engineering" ]
10.1111/tpj.12210
Quantification of growth-defense trade-offs in a common currency: Nitrogen required for phenolamide biosynthesis is not derived from ribulose-1,5- bisphosphate carboxylase/oxygenase turnover
Induced defenses are thought to be economical: growth and fitness-limiting resources are only invested into defenses when needed. To date, this putative growth-defense trade-off has not been quantified in a common currency at the level of individual compounds. Here, a quantification method for 15N-labeled proteins enab...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.7554/eLife.29736
CDK9-dependent RNA polymerase II pausing controls transcription initiation
Gene transcription can be activated by decreasing the duration of RNA polymerase II pausing in the promoter-proximal region, but how this is achieved remains unclear. Here we use a ‘multi-omics’ approach to demonstrate that the duration of polymerase pausing generally limits the productive frequency of transcription in...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
US 201715423007 A
Draft force detection on a vehicle having a linkage
A vehicle control system for controlling the height of a linkage on a vehicle having a continuously variable transmission (CVT) in which the linkage is automatically raised and lowered depending on a draft force detected by the vehicle including an input draft force detected by sensors in the CVT or driveline is inputt...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1083/jcb.201305139
RNA-based mechanisms underlying axon guidance
Axon guidance plays a key role in establishing neuronal circuitry. The motile tips of growing axons, the growth cones, navigate by responding directionally to guidance cues that pattern the embryonic neural pathways via receptormediated signaling. Evidence in vitro in the last decade supports the notion that RNA-based ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Neuroscience and Disorders of the Nervous System" ]
10.1007/s13524-019-00809-y
Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 1959–2016
Abstract This study examines the roles of age, period, and cohort in influenza mortality trends over the years 1959–2016 in the United States. First, we use Lexis surfaces based on Serfling models to highlight influenza mortality patterns as well as to identify lingering effects of early-life exposure to specific influ...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Integrative Biology: from Genes and Genomes to Systems" ]
W1970005760
Effect of chronic administration of vitamin E on the hemopoietic system in hypercholesterolemia
Hypercholesterolemia induces oxidative stress, which is known to have adverse effects on the integrity of cells. Hence, hypercholesterolemia may have adverse effects on the hemopoietic system. Vitamin E, an antioxidant, is being used by normo- and hypercholesterolemic subjects. It is, however, not known if vitamin E ha...
[ "Physiology in Health, Disease and Ageing" ]
W1985394689
Route selection for minimizing interference to primary users in Cognitive Radio Networks: A Reinforcement Learning approach
The dynamicity and unpredictability of channel availability in Cognitive Radio Networks (CRNs) have imposed a major challenge to the design of routing schemes. Generally speaking, routing enables Secondary Users (SUs) to select optimal routes, while minimizing interference to Primary Users (PUs), which is a key require...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1214/17-BA1065
Uncertainty quantification for the horseshoe (with discussion)
We investigate the credible sets and marginal credible intervals resulting from the horseshoe prior in the sparse multivariate normal means model. We do so in an adaptive setting without assuming knowledge of the sparsity level (number of signals). We consider both the hierarchical Bayes method of putting a prior on th...
[ "Mathematics" ]
W186895675
IMPROVING THE WRITING ABILITYOF THE TENTH GRADE STUDENTS OF SMA NU AL MA’RUF KUDUSIN ACADEMIC YEAR 2013/2014BY USING THINK-PAIR-SHARE (TPS) TECHNIQUE
English is one of the international languages in the world and becomes a foreign language in Indonesia. Writing is an important thing even though it is difficult skill to develop, it is very important to be taught. The descriptive text as a part of English material senior high school. It is considered as a difficult su...
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity" ]
10.1016/j.cplett.2017.02.087
Absorption cross sections and kinetics of formation of AlO at 298 K
The rate coefficient of the Al + O2 reaction has been measured in a laser ablation-fast flow tube apparatus by monitoring atomic Al resonance absorption and AlO laser induced fluorescence (LIF). The rate constant has been found to be k(298 K) = (1. 68 ± 0. 24) × 10−10 cm3 molecule−1 s−1. Under conditions of near-stoich...
[ "Physical and Analytical Chemical Sciences", "Fundamental Constituents of Matter" ]
10.1186/s13062-018-0211-z
Profiling microbial strains in urban environments using metagenomic sequencing data
Background: The microbial communities populating human and natural environments have been extensively characterized with shotgun metagenomics, which provides an in-depth representation of the microbial diversity within a sample. Microbes thriving in urban environments may be crucially important for human health, but ha...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems", "Computer Science and Informatics" ]
10.1039/C4NR00076E
The Role Of Size And Coating In Au Nanoparticles Incorporated Into Bi Component Polymeric Thin Film Transistors
We describe the effect of blending poly(3-hexylthiophene) (P3HT) with Au nanoparticles (AuNPs) on the performance of organic thin-film transistors. To this end we have used AuNPs of two different sizes coated with chemisorbed SAMs of oligophenyl-thiols possessing increasing lengths. The electrical characteristics of th...
[ "Condensed Matter Physics", "Materials Engineering" ]