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10.1088/1367-2630/17/12/123008
Self Induced Back Action Optical Trapping In Nanophotonic Systems
Optical trapping is an indispensable tool in physics and the life sciences. However, there is a clear trade off between the size of a particle to be trapped, its spatial confinement, and the intensities required. This is due to the decrease in optical response of smaller particles and the diffraction limit that governs...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
W2170054126
The max quasi-independent set problem
In this paper, we deal with the problem of finding quasi-independent sets in graphs. This problem is formally defined in three versions, which are shown to be polynomially equivalent. The one that looks most general, namely, f-max quasi-independent set, consists of, given a graph and a non-decreasing function f, findin...
[ "Mathematics", "Computer Science and Informatics" ]
725061
Teleost mucosal B1-like lymphocytes at the crossroad of tolerance and immunity
B cells are one of the main players of immunity, responsible for the production of immunoglobulins (Igs). In 2011, I was granted an ERC Starting grant to undertake the phenotypical and functional characterization of teleost B lymphocytes based on the hypothesis that they do not behave as mammalian B2 cells (conventiona...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2289550695
Variations on the IRE pattern in a French beginner task-based classroom
The use of the Initiation–Response–Evaluation (IRE) sequence is common in education and, although classroom research does not preclude its practice in pedagogy, it recommends introducing other forms of talk into teaching. The present study, inspired by Task-Based Language Teaching research on learner language, uses Con...
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity" ]
10.1016/j.compfluid.2018.02.014
Fluid flow around NACA 0012 airfoil at low-Reynolds numbers with hybrid lattice Boltzmann method
We simulate the two-dimensional fluid flow around National Advisory Committee for Aeronautics (NACA) 0012 airfoil using a hybrid lattice Boltzmann method (HLBM), which combines the standard lattice Boltzmann method with an unstructured finite-volume formulation. The aim of the study is to assess the numerical performan...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1111/imr.12363
TRIM21: A cytosolic Fc receptor with broad antibody isotype specificity
Antibodies are key molecules in the fight against infections. Although previously thought to mediate protection solely in the extracellular environment, recent research has revealed that antibody-mediated protection extends to the cytosolic compartment of cells. This postentry viral defense mechanism requires binding o...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1016/j.cmet.2014.04.016
DNAJC19, a mitochondrial cochaperone associated with cardiomyopathy, forms a complex with prohibitins to regulate cardiolipin remodeling
Prohibitins form large protein and lipid scaffolds in the inner membrane of mitochondria that are required for mitochondrial morphogenesis, neuronal survival, and normal lifespan. Here, we have defined the interactome of PHB2 in mitochondria and identified DNAJC19, mutated in dilated cardiomyopathy with ataxia, as bind...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
US 0018357 W
METHOD OF CRYSTALLIZING POLYCARBONATE PREPOLYMER
The invention relates to a method of crystallizing an aromatic polycarbonate prepolymer having a molecular weight of from about 1,000 to about 20,000 and having from about 5 to about 95 mole % aryl carbonate terminal end groups, based on total end groups, the method comprising effecting contact of the prepolymer with a...
[ "Synthetic Chemistry and Materials", "Materials Engineering" ]
10.2337/db16-1278
Disruption of lipid uptake in astroglia exacerbates diet-induced obesity
Neuronal circuits in the brain help to control feeding behavior and systemic metabolism in response to afferent nutrient and hormonal signals. Although astrocytes have historically been assumed to have little relevance for such neuroendocrine control, we investigated whether lipid uptake via lipoprotein lipase (LPL) in...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
W2050801031
Unpacking the 2 × 2 table
Statistics estimated from a 2 × 2 contingency table, such as sensitivity, specificity, and likelihood ratios, are usually presented in contexts of diagnostic decision making or evaluation of screening tests. However, their use is not restricted to those contexts. The purpose of this article is to summarize for clinicia...
[ "Mathematics", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W1990678906
Narrow Band Imaging Cystoscopy and Bipolar Plasma Vaporization for Large Nonmuscle-invasive Bladder Tumors—Results of a Prospective, Randomized Comparison to the Standard Approach
To evaluate the efficacy of narrow band imaging (NBI) cystoscopy associated with bipolar plasma vaporization (BPV) in cases of large nonmuscle-invasive bladder tumors (NMIBTs) compared with white light cystoscopy (WLC) and monopolar transurethral resection of bladder tumors (TURBTs).A total of 220 cases with ≥ 1 bladde...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
10.1016/j.pbi.2018.03.008
Volatiles as inducers and suppressors of plant defense and immunity — origins, specificity, perception and signaling
Volatiles from attacked plants, microbes and herbivores can enhance plant defenses. However, the absence of volatiles rather than their presence has sometimes been associated with enhanced defense, suggesting that volatiles may also act as defense suppressors. Recent work provides a potential mechanistic explanation fo...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution" ]
637015
Next-Generation quantum light-matter interfaces based on atom arrays and nanophotonic waveguides
The fellow will investigate the use of atom arrays as next-generation quantum light-matter interfaces. He will be hosted by the Institute of Photonic Sciences in Barcelona, Spain. At ICFO, he will be integrated in the Theoretical Quantum-Nano Physics group under the supervision of Prof. Darrick Chang. Quantum atom-lig...
[ "Fundamental Constituents of Matter", "Condensed Matter Physics", "Systems and Communication Engineering" ]
638707
Black holes and their host galaxies: coevolution across cosmic time
Galaxy formation is one of the most fascinating yet challenging fields of astrophysics. The desire to understand galaxy formation has led to the design of ever more sophisticated telescopes which show a bewildering variety of galaxies in the Universe. However, the degree to which an interpretation of this wealth of dat...
[ "Universe Sciences" ]
224585
Hypoglycaemia - redefining solutions for better lives
Diabetes is one of the most prevalent global non-communicable diseases, affecting 60 million people in Europe, 10% of whom with type 1 diabetes. Normalising elevated glucose levels decreases symptoms, prevents microvascular complications, improves cardiovascular health and saves lives, but creates a significant risk f...
[ "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1074/mcp.M116.058263
Proteomic analysis of the plasmodium berghei gametocyte egressome and vesicular bioid of osmiophilic body proteins identifies merozoite trap-like protein (MTRAP) as an essential factor for parasite transmission
Malaria transmission from an infected host to the mosquito vector requires the uptake of intraerythrocytic sexual precursor cells into the mosquito midgut. For the release of mature extracellular gametes two membrane barriers-the parasite parasitophorous vacuole membrane and the host red blood cell membrane-need to be ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy" ]
10.1093/scan/nsw074
Conditioned social dominance threat: Observation of others' social dominance biases threat learning
Social groups are organized along dominance hierarchies, which determine how we respond to threats posed by dominant and subordinate others. The persuasive impact of these dominance threats on mental and physical well-being has been well described but it is unknown how dominance rank of others bias our experience and l...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity", "The Social World and Its Interactions" ]
W979843761
Entrepreneurial Growth and Ownership under Market Socialism in China: A Longitudinal Case Study of Small Business Growth
How firms grow is still a mystery and a definitive explanation remains elusive. This is especially the case for emerging economies, where the development of research into business growth has been notably slow whilst emerging business ventures are developing at hyper speed. Since most empirical studies have focused on t...
[ "Individuals, Markets and Organisations", "The Social World and Its Interactions" ]
10.1084/jem.20170829
Developmental origin and maintenance of distinct testicular macrophage populations
Testicular macrophages (tMφ) are the principal immune cells of the mammalian testis. Beyond classical immune functions, they have been shown to be important for organogenesis, spermatogenesis, and male hormone production. In the adult testis, two different macrophage populations have been identified based on their dist...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1109/JSTSP.2018.2877405
Subspace Estimation From Incomplete Observations A High Dimensional Analysis
We present a high-dimensional analysis of three popular algorithms, namely, Oja's method, GROUSE, and PETRELS, for subspace estimation from streaming and highly incomplete observations. We show that, with proper time scaling, the time-varying principal angles between the true subspace and its estimates given by the alg...
[ "Mathematics", "Computer Science and Informatics" ]
W1985517477
Microconcrete with partial replacement of Portland cement by fly ash and hydrated lime addition
Abstract The reduction in Portland cement consumption means lower CO 2 emissions. Partial replacement of Portland cement by pozzolans such as fly ash has its limitations due to the quantity of calcium hydroxide generated in the mix. In this work we have studied the contribution of the addition of hydrated lime to Portl...
[ "Materials Engineering", "Products and Processes Engineering", "Physical and Analytical Chemical Sciences" ]
10.1098/rsta.2011.0338
Water in exoplanets
Exoplanets—planets orbiting around stars other than our own Sun—appear to be common. Significant research effort is now focused on the observation and characterization of exoplanet atmospheres. Species such as water vapour, methane, carbon monoxide and carbon dioxide have been observed in a handful of hot, giant, gaseo...
[ "Physical and Analytical Chemical Sciences", "Universe Sciences" ]
10.1038/nature13821
Quantum tomography of an electron
The complete knowledge of a quantum state allows the prediction of the probability of all possible measurement outcomes, a crucial step in quantum mechanics. It can be provided by tomographic methods which have been applied to atomic, molecular, spin and photonic states. For optical or microwave photons, standard tomog...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
10.1007/978-3-642-54631-0_21
Leakage Resilient Signatures With Graceful Degradation
We investigate new models and constructions which allow leakage-resilient signatures secure against existential forgeries, where the signature is much shorter than the leakage bound. Current models of leakage-resilient signatures against existential forgeries demand that the adversary cannot produce a new valid message...
[ "Computer Science and Informatics" ]
W1524502272
Control of protein concentrations in heterogeneous cell populations
In this work we propose a synthetic gene circuit for controlling the variability in protein concentration at a population level. The circuit, based on the use of an intracellular nonlinear controller coupled to a cell-to-cell communication mechanism, allows for independent control of the mean and variance of a signalli...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Systems and Communication Engineering", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1093/gerona/glz276
Dietary Restriction Improves Fitness of Aging Parents But Reduces Fitness of Their Offspring in Nematodes
Dietary restriction (DR) is a well-established intervention to extend lifespan across taxa. Recent studies suggest that DR-driven lifespan extension can be cost-free, calling into question a central tenant of the evolutionary theory of aging. Nevertheless, boosting parental longevity can reduce offspring fitness. Such ...
[ "Physiology in Health, Disease and Ageing", "Environmental Biology, Ecology and Evolution" ]
10.1016/j.neuron.2020.03.022
PNOC<sup>ARC</sup> Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding
Calorie-rich diets induce hyperphagia and promote obesity, although the underlying mechanisms remain poorly defined. We find that short-term high-fat-diet (HFD) feeding of mice activates prepronociceptin (PNOC)-expressing neurons in the arcuate nucleus of the hypothalamus (ARC). PNOCARC neurons represent a previously u...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
10.1103/PhysRevB.89.140402
Bias-controlled ultrafast demagnetization in magnetic tunnel junctions
We report on the possibility of controlling the maximum demagnetization induced by a femtosecond laser pulse in a CoFeB-based magnetic tunnel junction, by tuning the external bias applied to the junction. We explain this effect in terms of laser-induced spin-polarized currents which can be controlled by tuning the cond...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
W2021634022
Tetrandrine Induces Mitochondria-Mediated Apoptosis in Human Gastric Cancer BGC-823 Cells
Tetrandrine, a bis-benzylisoquinoline alkaloid isolated from the dried root of Hang-Fang-Chi (Stephaniatetrandra S. Moore), has been reported to possess anti-cancer effects on many tumors. In this study, we investigated tetrandrine-induced apoptosis on human gastric cancer BGC-823 cells in vitro and in vivo. The result...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
726001
Topological nano-photonics
One of the most fascinating phenomena in nature is the interplay between quantum mechanics and the flow of electrons in solids. A tangible example is the quantum hall effect, where electrons flow with virtually zero dissipation. That is because electrons can flow only in one direction, which makes them move around obje...
[ "Condensed Matter Physics", "Synthetic Chemistry and Materials", "Systems and Communication Engineering", "Materials Engineering" ]
10.3389/fmicb.2015.00865
Warming reduces the cover and diversity of biocrust-forming mosses and lichens, and increases the physiological stress of soil microbial communities in a semi-arid Pinus halepensis plantation
Soil communities dominated by lichens and mosses (biocrusts) play key roles in maintaining ecosystem structure and functioning in drylands worldwide. However, few studies have explicitly evaluated how climate change-induced impacts on biocrusts affect associated soil microbial communities. We report results from a fiel...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
10.1039/d0sc03727c
Engineering micromechanics of soft porous crystals for negative gas adsorption
We characterise the elastic properties of molecular building blocks and how they impact the mechanical properties of soft porous crystals.
[ "Condensed Matter Physics", "Materials Engineering" ]
Q4430522
Implementação de tecnologia inovadora de segurança microbiológica em produtos à base de carne orgânicos, convencionais e livres melhorados JK sp z o.o. — Plant Meat Jasiołka em Dukla
O resultado do projeto através da aquisição de ativos fixos e obras de construção será a criação e implementação de uma nova tecnologia de produção de produtos à base de carne com a adição de soro de leite sem adição de nitritos e nitratos. A nova tecnologia será inovadora e será a primeira a ser aplicada à escala indu...
[ "Products and Processes Engineering", "Biotechnology and Biosystems Engineering" ]
10.1137/16M1066920
Asymptotics Of Stochastic Protein Assembly Models
Protein polymerization is involved in many important biological phenomena and gives rise to spontaneous formation of amyloid fibrils or, more generally, polymers. The starting point of this process, called nucleation, exhibits an important variability among replicated experiments. To analyze the stochastic nature of th...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1109/TPEL.2017.2658340
Modeling Of Vsc Based Power Systems In The Extended Harmonic Domain
Averaged modeling is a commonly used approach used to obtain mathematical representations of VSC-based systems. However, essential characteristics mainly related to the modulation process and the harmonic distortion of the signals are not able to be accurately captured and analyzed. The extended harmonic domain (EHD) h...
[ "Systems and Communication Engineering", "Mathematics" ]
10.1016/j.dnarep.2015.09.014
Chromatin dynamics after DNA damage: The legacy of the access-repair-restore model
Eukaryotic genomes are packaged into chromatin, which is the physiological substrate for all DNA transactions, including DNA damage and repair. Chromatin organization imposes major constraints on DNA damage repair and thus undergoes critical rearrangements during the repair process. These rearrangements have been integ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.2514/1.46681
Light Levitated Geostationary Cylindrical Orbits Are Feasible
This paper discusses a new family of non-Keplerian orbits for solar sail spacecraft displaced above or below the Earth's equatorial plane. The work aims to prove the assertion in the literature that displaced geostationary orbits exist, possibly to increase the number of available slots for geostationary communications...
[ "Universe Sciences", "Systems and Communication Engineering" ]
885996
Health, environment, agriculture, rural development: training network for land management
Livestock farming is increasingly in the spotlight because of its impacts on the environment and human health. Global livestock production, specifically ruminant farming, has been associated with land use change, methane emissions, climate change, deforestation and biodiversity loss. At the same time, consumption of li...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Products and Processes Engineering" ]
EP 89810221 A
Device for the sequential treatment of submerged objects and kit containing such a device.
The device is intended for the sequential treatment of submerged objects by means of dissolved reactive products, and comprises the following elements: a container (1) intended to contain the solution of reactive products, a receptacle (2) enabling the objects to be treated to be kept submerged in the container (1), a ...
[ "Products and Processes Engineering", "Materials Engineering" ]
224639
Information diffusion on networks
This two-year research project aims to analyse the simultaneous diffusion of multiple pieces of information on (social) networks; how messages may interact, how rumours diffuse in the presence of truthful information and verification, and how network structure interacts with the virality of information. Misinformation ...
[ "Individuals, Markets and Organisations", "Computer Science and Informatics", "The Social World and Its Interactions" ]
172360
The origin of heavy elements: a nuclear physics and astrophysics challenge
Where in the universe are heavy elements synthesized? How are these elements produced? These are two exciting and interdisciplinary questions in nuclear astrophysics today and will be investigated in my ERC project EUROPIUM. The favored astrophysical sites are neutrino-driven winds following core-collapse supernovae an...
[ "Universe Sciences", "Fundamental Constituents of Matter" ]
10.1371/journal.pone.0051540
The Smc5-Smc6 Complex Regulates Recombination at Centromeric Regions and Affects Kinetochore Protein Sumoylation during Normal Growth
The Smc5-Smc6 complex in Saccharomyces cerevisiae is both essential for growth and important for coping with genotoxic stress. While it facilitates damage tolerance throughout the genome under genotoxin treatment, its function during unperturbed growth is mainly documented for repetitive DNA sequence maintenance. Here ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1523/JNEUROSCI.4330-13.2014
Impaired path integration and grid cell spatial periodicity in mice lacking GluA1-containing AMPA receptors
The hippocampus and the parahippocampal region have been proposed to contribute to path integration. Mice lacking GluA1-containing AMPA receptors (GluA1-/- mice) were previously shown to exhibit impaired hippocampal place cell selectivity. Here we investigated whether path integration performance and the activity of gr...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1016/j.jeconom.2019.10.009
Posterior distribution of nondifferentiable functions
This paper examines the asymptotic behavior of the posterior distribution of a possibly nondifferentiable function g(θ), where θ is a finite-dimensional parameter of either a parametric or semiparametric model. The main assumption is that the distribution of a suitable estimator θ̂n, its bootstrap approximation, and th...
[ "Mathematics" ]
IN 2006000293 W
INHERENTLY COLOURED POLYESTER POLYMERS, FIBERS OR FILAMENTS AND PROCESS FOR PRODUCING THEM
Inherently coloured polyester polymers, fibers or filaments with controlled branching or even linear structures comprising chromophoric co-monomer in their backbone. Processes for preparing the above inherently coloured polyester polymers, fibers or filaments is also disclosed. Inherently coloured polyester of the inve...
[ "Synthetic Chemistry and Materials", "Materials Engineering" ]
10.11600/1692715x.18204
«No he sido juvenólogo»: una conversación con Carlos Mario Perea
El artículo aborda la trayectoria del historiador colombiano Carlos Mario Perea, centrándose en sus aportaciones a los estudios sobre juventud. A partir de una conversación con Carles Feixa, se reconstruyen las principales etapas de su vida, como joven, militante político e investigador, desde sus recuerdos como estudi...
[ "The Study of the Human Past", "The Social World and Its Interactions" ]
10.1051/0004-6361/201629946
Co2 Infrared Emission As A Diagnostic Of Planet Forming Regions Of Disks
[Abridged] The infrared ro-vibrational emission lines from organic molecules in the inner regions of protoplanetary disks are unique probes of the physical and chemical structure of planet forming regions and the processes that shape them. The non-LTE excitation effects of carbon dioxide (CO2) are studied in a full dis...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
10.1016/j.ccell.2017.05.006
Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
Intrahepatic cholangiocarcinoma (ICC) is a highly malignant, heterogeneous cancer with poor treatment options. We found that mitochondrial dysfunction and oxidative stress trigger a niche favoring cholangiocellular overgrowth and tumorigenesis. Liver damage, reactive oxygen species (ROS) and paracrine tumor necrosis fa...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
724705
Pushing the frontiers of biological imaging with genetically encoded fluorescence switches
Biological imaging is essential for revealing the inner workings of living systems. Among the numerous imaging modalities, light microscopy has revolutionized biological research. In addition to advances in optics and detectors, imaging has benefited from the development of molecular tools to observe biomolecules in ac...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Prevention, Diagnosis and Treatment of Human Diseases", "Physical and Analytical Chemical Sciences" ]
W2587632062
Leadership through fellowship: distributed leadership in a professional recognition scheme for university educators
ABSTRACTResearchers in the field of teaching and learning in higher education have identified concerns with top-down leadership models. Distributed (or shared) leadership approaches may provide more successful engagement with institutional change agendas, and provide more options to reward and recognise staff leading t...
[ "The Social World and Its Interactions", "Individuals, Markets and Organisations" ]
W637340501
Research Design in European Studies: Establishing Causality in Europeanization
Europeanization: The Challenge of Establishing Causality C.M.Radaelli Looking for Causality in the Literature on Europeanization T.Exadaktylos & C.M.Radaelli Causality in Quantitative Approaches A.E.Toller Europeanization: A Critical Realist Perspective I.Bache , S.Bulmer & D.Gunay Discursive Institutional Analytical S...
[ "Institutions, Governance and Legal Systems", "The Social World and Its Interactions", "Individuals, Markets and Organisations" ]
982022
Bio-Based strategies and roadmaps for enhanced rural and regional development in the eu
The overall goal of BE-Rural is to realise the potential of regional and local bio-based economies by supporting relevant actors in the participatory development of bioeconomy strategies and roadmaps. BE-Rural will investigate the particular characteristics of the selected regions at a macro level, as well as existing ...
[ "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering", "Human Mobility, Environment, and Space" ]
W2170991750
Perceptions of individuals living with spinal cord injury toward preference-based quality of life instruments: a qualitative exploration
Generic preference-based health-related quality of life instruments are widely used to measure health benefit within economic evaluation. The availability of multiple instruments raises questions about their relative merits and recent studies have highlighted the paucity of evidence regarding measurement properties in ...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Neuroscience and Disorders of the Nervous System" ]
W2005554182
Analyte quantification with comprehensive two-dimensional gas chromatography: Assessment of methods for baseline correction, peak delineation, and matrix effect elimination for real samples
Comprehensive two-dimensional gas chromatography (GC×GC) is used widely to separate and measure organic chemicals in complex mixtures. However, approaches to quantify analytes in real, complex samples have not been critically assessed. We quantified 7 PAHs in a certified diesel fuel using GC×GC coupled to flame ionizat...
[ "Physical and Analytical Chemical Sciences", "Computer Science and Informatics" ]
10.1136/jnnp-2016-314728
Reward and punishment enhance motor adaptation in stroke
Background and objective The effects of motor learning, such as motor adaptation, in stroke rehabilitation are often transient, thus mandating approaches that enhance the amount of learning and retention. Previously, we showed in young individuals that reward and punishment feedback have dissociable effects on motor ad...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
10.1038/ncomms6360
Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity
Primary immunodeficiency disorders enable identification of genes with crucial roles in the human immune system. Here we study patients suffering from recurrent bacterial, viral and Cryptosporidium infections, and identify a biallelic mutation in the MAP3K14 gene encoding NIK (NF- B-inducing kinase). Loss of kinase act...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1371/journal.pone.0125250
Influence of extracellular matrix components on the expression of integrins and regeneration of adult retinal ganglion cells
Purpose Retinal ganglion cells (RGCs) are exposed to injury in a variety of optic nerve diseases including glaucoma. However, not all cells respond in the same way to damage and the capacity of individual RGCs to survive or regenerate is variable. In order to elucidate factors that may be important for RGC survival and...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
Q2072357
LAVADO DE COCHES EN AUTOSERVICIO 24/24
LAVADO DE COCHES EN AUTOSERVICIO ABIERTO 24/24 TAMBIÉN CON CONDICIONES INVERNALES (CONGELAR) YA QUE FUNCIONA EN AMBIENTE CERRADO Y VIDEOVIGILANCIA CALENTADA Y GESTIONADA A DISTANCIA. GESTIÓN AUTOMÁTICA DE LA APERTURA DE LAS PUERTAS DENTRO Y FUERA DEL COCHE. RECUPERACIÓN Y RECICLAJE DEL AGUA DE PROCESAMIENTO. POSIBILIDA...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1016/j.bpj.2015.02.032
The mechanical properties of early drosophila embryos measured by high-speed video microrheology
In early development, Drosophila melanogaster embryos form a syncytium, i. e. , multiplying nuclei are not yet separated by cell membranes, but are interconnected by cytoskeletal polymer networks consisting of actin and microtubules. Between division cycles 9 and 13, nuclei and cytoskeleton form a two-dimensional corti...
[ "Condensed Matter Physics", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.5194/isprs-archives-xlii-2-w15-743-2019
THE DIGITALIZATION OF ANCIENT EGYPTIAN COFFINS: A DISCUSSION OVER DIFFERENT TECHNIQUES FOR RECORDING FINE DETAILS
. This work starts from the request to have a physical high-resolution 3D model of the external, anthropoid coffin of the scribe Butehamon, held at the Museo Egizio, Turin. At the time of writing, a replica of the coffin, based on this survey work, functions as final and focal installation of the temporary exhibition A...
[ "The Study of the Human Past", "Computer Science and Informatics", "Physical and Analytical Chemical Sciences" ]
W2519496951
The Highly Insidious Extreme Phishing Attacks
One of the most severe and challenging threats to Internet security is phishing, which uses spoofed websites to steal users' passwords and online identities. Phishers mainly use spoofed emails or instant messages to lure users to the phishing websites. A spoofed email or instant message provides the first-layer context...
[ "Computer Science and Informatics" ]
interreg_1686
Intermodal Connections in Adriatic-Ionian Region to Upgrowth Seamless solutions for passenger
ICARUS aims at improving passenger intermodal transport connections and easing coast-hinterland sustainable accessibility, promoting car-independent lifestyles. The project fights against problems generated by the massive use of private cars by introducing solutions based on innovative technologies to adapt smart mobil...
[ "Products and Processes Engineering", "Computer Science and Informatics", "Human Mobility, Environment, and Space" ]
W2066541517
Responses of two lithosomes of Lower Cretaceous coarse clastic rocks to tectonism in Kuqa foreland sub-basin, Northern Tarim Basin, Northwest China
Abstract Coarse clastic rocks, developed widely at foredeep adjacent to orogene, were usually regarded as the mark of renewed thrusting action. However a good example from the Lower Cretaceous in Kuqa foreland sub-basin illustrated that the coarse clastic rocks developed not only in initial thrusting stage but in early...
[ "Earth System Science" ]
864045
Deep Serpentinization, H2, and high-pressure abiotic CH4
The deep subsurface biosphere is the largest microbiological habitat on Earth, with biomass and contribution to biogeochemical cycles comparable to surface biosphere. Deciphering the parameters that control and sustain deep subsurface life is vital in understanding the functioning of our planet, and additionally provid...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2163558759
Species distribution and depth habitat of recent planktic foraminifera in Fram Strait, Arctic Ocean
To describe the horizontal and vertical distribution of recent planktic foraminifera in Fram Strait (Arctic), plankton samples were collected in the early summer of 2011 using a MultiNet sampler (>63 µm) at 10 stations along a west–east transect at 78°50′N. Five depth intervals were sampled from the sea surface down to...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
Q3847243
Support for small enterprises with a turnover of more than BGN 500 000 to overcome the economic impact of the COVID-19 pandemic
Support for small enterprises with a turnover of more than BGN 500 000 to overcome the economic impact of the COVID-19 pandemic
[ "Individuals, Markets and Organisations" ]
10.1007/978-3-319-62127-2_43
A Polynomial Kernel For Distance Hereditary Vertex Deletion
A graph is distance-hereditary if for any pair of vertices, their distance in every connected induced subgraph containing both vertices is the same as their distance in the original graph. The Distance-Hereditary Vertex Deletion problem asks, given a graph G on n vertices and an integer k, whether there is a set S of a...
[ "Mathematics", "Computer Science and Informatics" ]
10.1080/2150704X.2016.1142681
Segmentation And Tracking Of Marine Cellular Clouds Observed By Geostationary Satellites
Marine stratocumulus MSC are shallow marine boundary layer clouds that have a significant cooling contribution to the Earth’s radiative balance. The amplitude of this cooling effect strongly depends on the properties of closed and open cells comprising MSC cloud fields. Systematic study of the underlying processes asso...
[ "Earth System Science", "Computer Science and Informatics" ]
311736
Elucidating early pathogenic mechanisms of neurodegeneration in Parkinson's disease through a humanized dynamic in vitro model
Our understanding of Parkinson’s disease (PD) pathogenesis is currently limited by difficulties in obtaining live neurons from patients and the inability to model the sporadic, most frequent, form of PD. It may be possible to overcome these challenges by reprogramming somatic cells from patients into induced pluripoten...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1145/3318464.3389721
On Multiple Semantics For Declarative Database Repairs
We study the problem of database repairs through a rule-based framework that we refer to as Delta Rules. Delta rules are highly expressive and allow specifying complex, cross-relations repair logic associated with Denial Constraints, Causal Rules, and allowing to capture Database Triggers of interest. We show that ther...
[ "Computer Science and Informatics" ]
10.1371/journal.pone.0053179
Comprehensive Histone Phosphorylation Analysis and Identification of Pf14-3-3 Protein as a Histone H3 Phosphorylation Reader in Malaria Parasites
The important role of histone posttranslational modifications, particularly methylation and acetylation, in Plasmodium falciparum gene regulation has been established. However, the role of histone phosphorylation remains understudied. Here, we investigate histone phosphorylation utilizing liquid chromatography and tand...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1016/j.chom.2017.11.002
A Large Polysaccharide Produced by Helicobacter hepaticus Induces an Anti-inflammatory Gene Signature in Macrophages
Interactions between the host and its microbiota are of mutual benefit and promote health. Complex molecular pathways underlie this dialog, but the identity of microbe-derived molecules that mediate the mutualistic state remains elusive. Helicobacter hepaticus is a member of the mouse intestinal microbiota that is tole...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
10.1109/LPT.2016.2625808
Unity Rate Codes Maximize The Normalized Throughput Of On Off Keying Visible Light Communication
In this letter, we aim for maximizing the throughput of a visible light communication (VLC) system. Explicitly, we conceive a soft-in soft-out decoder providing soft feedback for the classic run length limited (RLL) codes, hence facilitating iterative decoding for exchanging valuable extrinsic information between the R...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
US 9924482 W
NETWORK DOCUMENT DELIVERY SYSTEM
A system of networked computers and peripherals and document delivery software which provides a user with a familiar simple user interface (12) to deliver documents to a variety of different destinations. Each document generation device participating in the system is provided with a unified print driver which translate...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
W1639798798
Design for manufacturing of surfaces to improve accuracy in Fused Deposition Modeling
Fused Deposition Modeling is an Additive Manufacturing technology able to fabricate prototypes, tooling and functional parts without geometrical complexity limitations. Despite of the potential advantages of this technology, a limiting aspect of its industrial diffusion is the obtainable accuracy. The literature highli...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1088/0004-637X/803/1/40
Ultraviolet Spectroscopy Of Type Iib Supernovae Diversity And The Impact Of Circumstellar Material
We present new Hubble Space Telescope (HST) multi-epoch ultraviolet (UV) spectra of the bright Type IIb SN 2013df, and undertake a comprehensive analysis of the set of four SNe IIb for which HST UV spectra are available (SN 1993J, SN 2001ig, SN 2011dh, and SN 2013df). We find strong diversity in both continuum levels a...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
10.1038/nature12791
Cytokinin signalling inhibitory fields provide robustness to phyllotaxis
How biological systems generate reproducible patterns with high precision is a central question in science. The shoot apical meristem (SAM), a specialized tissue producing plant aerial organs, is a developmental system of choice to address this question. Organs are periodically initiated at the SAM at specific spatial ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1016/j.jvolgeores.2013.07.009
Long-range correlations identified in time-series of volcano seismicity during dome-forming eruptions using detrended fluctuation analysis
Understanding the underlying structure of data from volcano monitoring is essential to identify precursors to changes in eruptive activity and to comprehend volcanic processes. However, effective analysis of longer-term trends in these signals is challenging as volcanic data are not necessarily statistically stationary...
[ "Mathematics", "Earth System Science" ]
10.1007/s00441-016-2427-5
Dynamic zonation of liver polyploidy
The liver is a polyploid organ, consisting of hepatocytes with one or two nuclei each containing 2, 4, 8 or more haploid chromosome sets. The dynamic changes in the spatial distributions of polyploid classes across the liver lobule, its repeating anatomical unit, have not been characterized. Identifying these spatial p...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing" ]
172136
Addressing neural declines to promote healthy ageing
This multidisciplinary proposal combines behavioural science, neuroscience, and ageing research with the goal of providing an innovative, state-of-the-art approach to address age related declines in human performance. The ageing population presents unprecedented challenges for society, and developing novel approaches ...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing", "The Human Mind and Its Complexity" ]
10.1080/19420889.2015.1029210
Algal Viruses Hitchhiking On Zooplankton Across Phytoplankton Blooms
Viruses infecting marine phytoplankton are key biogeochemical 'engines' of the oceans, regulating the dynamics of algal populations and the fate of their extensive blooms. In addition they are important ecological and evolutionary drivers of microbial diversification. Yet, little is known about mechanisms influencing v...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
172682
Preparedness and resilience to address urban vulnerability
The challenge posed by urban vulnerability is immense and is being compounded by rapid unplanned urbanisation, climate change and resource pressures. While the realisation that there is a fundamental shift in the landscape of crises to cities is no longer contested, aid actors are nonetheless grappling with the comple...
[ "Human Mobility, Environment, and Space", "Institutions, Governance and Legal Systems", "The Social World and Its Interactions" ]
W3092188341
Pressure Analysis of the Initial Process of Diffusion Combustion Surge in a 350 kW Gas Boiler
In order to meet the increasingly stringent requirements for nitrogen oxides (NOx) emissions from gas boilers, flue gas recirculation (FGR) technology is commonly used to achieve ultra-low NOx emissions. However, under some ultra-low NOx combustion conditions with FGR, a surge phenomenon occurs in the boiler, which cau...
[ "Physical and Analytical Chemical Sciences", "Products and Processes Engineering" ]
10.1016/j.neuroimage.2019.03.031
The spatiotemporal neural dynamics underlying perceived similarity for real-world objects
The degree to which we perceive real-world objects as similar or dissimilar structures our perception and guides categorization behavior. Here, we investigated the neural representations enabling perceived similarity using behavioral judgments, fMRI and MEG. As different object dimensions co-occur and partly correlate,...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1007/s11769-018-0942-x
China’s Global Shipping Connectivity: Internal and External Dynamics in the Contemporary Era (1890–2016)
China’s global shipping connectivity had been somewhat overlooked as the bulk of related studies predominantly focused on the throughput volume of its own port cities. This article tackles such lacunae by providing a relational perspective based on the extraction of vessel movement archives from the Lloyd’s List corpus...
[ "Human Mobility, Environment, and Space", "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems" ]
10.1007/s10584-020-02842-y
Public views on carbon taxation and its fairness: a computational-linguistics analysis
Carbon taxes evoke a variety of public responses, often with negative implications for policy support, implementation, and stringency. Here we use topic modeling to analyze associations of Spanish citizens with a policy proposal to introduce a carbon tax. This involves asking two key questions, to elicit (1) citizens’ ...
[ "The Social World and Its Interactions", "Individuals, Markets and Organisations", "Computer Science and Informatics" ]
641759
Peristaltic multistage micro-mechanical pump for next generation diabetes management
More than 30 million people are living with diabetes in the EU, with a prevalence expected to grow to over 10% of the adult population by the year 2030. Despite modern treatments, the life expectancy of patients with type 1 diabetes remains reduced as compared to healthy people due to lack of efficient therapies. An “a...
[ "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases", "Materials Engineering" ]
10.3982/ECTA13533
Altruism In Networks
We provide the first theoretical analysis of altruism in networks. Agents are embedded in a fixed, weighted network and care about their direct friends. Given some initial distribution of incomes, they may decide to support their poorer friends. We study the resulting non-cooperative transfer game. Our analysis highlig...
[ "Mathematics", "Individuals, Markets and Organisations", "The Social World and Its Interactions" ]
267985
Electroweak Symmetry Breaking, Flavor and Dark Matter: One Solution for Three Mysteries
In the next five years, experiments will give us a unique opportunity to unravel the mysteries of Electroweak Symmetry Breaking, Flavor and Dark Matter. The LHC at CERN will push the Energy frontier well into the TeV region and shed light on electroweak symmetry breaking. The LHCb experiment, super-B factories and oth...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
10.1016/j.cellsig.2019.03.010
The role and therapeutic potential of connexins, pannexins and their channels in Parkinson's disease
Lack of effective medication for slowing down progression of Parkinson's disease (PD) as a highly prevalent neurodegenerative disorder requires novel avenues of scientific investigation to elucidate the underlying molecular and cellular mechanisms. Studying connexins, pannexins and their channels has uncovered their po...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
224215
Chemistry and transport properties of bridgmanite controlling lower-mantle dynamics
Seismic observations imply that slab descent and plume ascent are impeded in the mid-mantle (MM) (depths of 660–1000 km, pressures of 23–40 GPa). A recent evaluation of viscosity variation suggested the presence of a viscosity increase or maximum in the MM that could drag the slab and plume motions. The viscosity varia...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics", "Earth System Science" ]
W1862681752
Intracranial hemangiopericytoma: MR imaging findings and diagnostic usefulness of minimum ADC values
To describe the clinical and magnetic resonance (MR) imaging features of primary intracranial hemangiopericytoma (HPC), and to assess the usefulness of minimum apparent diffusion coefficient (MinADC) value of HPC in the differential diagnosis from meningioma.From 2004 to 2010, fifteen patients with primary intracranial...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Neuroscience and Disorders of the Nervous System" ]
10.1039/c6ce01094f
Structural analysis and optical properties of the Bi2−xYxWO6 system
The structural and optical properties of the Bi2−xYxWO6, system are reported.
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
W1591571939
F 0 estimation using SRH based on TV-CAR speech analysis
This paper proposes novel robust speech F 0 estimation using SRH (Summation Residual Harmonics) based on TV-CAR (Time-Varying Complex AR) analysis. We have already proposed robust F 0 estimation based on the TV-CAR analysis in which weighted auto-correlation for complex residual signals is used as the criterion. In the...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
W1991048147
Surrogation and the politics of remembering slavery in Savannah, Georgia (USA)
Abstract There are growing calls from some African Americans, particularly in the U.S. South, to create sites of counter-memory that recognize the often forgotten historical struggles and contributions of the enslaved. Commemoration of slavery is not only a contentious issue for whites but also African Americans, who d...
[ "The Study of the Human Past", "The Social World and Its Interactions", "Human Mobility, Environment, and Space" ]
US 2004/0004646 W
FERRIC ORGANIC COMPOUNDS, USES THEREOF AND METHODS OF MAKING SAME
The present invention is directed to forms of ferric organic compounds, uses thereof, and methods of making same. The present invention discloses a novel physical form of ferric citrate with dissolution properties desirable for use in medicine, including the treatment of hyperphosphatemia and metabolic acidosis.
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.2119/molmed.2016.00002
Clearance of cell remnants and regeneration of injured muscle depend on soluble pattern recognition receptor PTX3
The signals causing resolution of muscle inflammation are only partially characterized. The long pentraxin PTX3, which modulates leukocyte recruitment and activation, could contribute. We analyzed the expression of PTX3 after muscle injury and verified whether hematopoietic precursors are a source of the protein. The k...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
224175
Competition for space in development and diseases
Developing tissues have a remarkable plasticity illustrated by their capacity to regenerate and form normal organs despite strong perturbations. This requires the adjustment of single cell behaviour to their neighbours and to tissue scale parameters. The modulation of cell growth and proliferation was suggested to be d...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
10.1371/journal.pone.0019869
Dynamical patterns of cattle trade movements
Despite their importance for the spread of zoonotic diseases, our understanding of the dynamical aspects characterizing the movements of farmed animal populations remains limited as these systems are traditionally studied as static objects and through simplified approximations. By leveraging on the network science appr...
[ "Computer Science and Informatics", "Earth System Science", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1038/s41598-020-62484-z
Multi-resolution convolutional neural networks for inverse problems
AbstractInverse problems in image processing, phase imaging, and computer vision often share the same structure of mapping input image(s) to output image(s) but are usually solved by different application-specific algorithms. Deep convolutional neural networks have shown great potential for highly variable tasks across...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]