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10.1142/S0219493715500124
Mixing For Invertible Dynamical Systems With Infinite Measure
In a recent paper, Melbourne and Terhesiu [Operator renewal theory and mixing rates for dynamical systems with infinite measure, Invent. Math. 189 (2012) 61–110] obtained results on mixing and mixing rates for a large class of noninvertible maps preserving an infinite ergodic invariant measure. Here, we are concerned w...
[ "Mathematics" ]
632365
Antibody engineering by natural selection and by design
Antibodies represent a powerful defense mechanism due to their capacity to link specific antigen recognition with effector functions and are currently developed as drugs for prophylaxis and therapy of infectious diseases. The generation of antibody diversity represents a remarkable example of protein engineering that i...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
3743287
Fair pensions and population ageing
Demographic changes in survival rates and age structures require adaptions in public policies. This grant will produce a social benefit by providing policy makers with two kinds of tools that they will need to make these adaptions, fair normal pension ages and consistently up-to-date measures of population ageing that ...
[ "Individuals, Markets and Organisations", "Human Mobility, Environment, and Space", "The Social World and Its Interactions" ]
W2011771713
Physiologically based modeling of the pharmacokinetics of acetaminophen and its major metabolites in humans using a Bayesian population approach
The principal aim of this study was to develop, validate, and demonstrate a physiologically based pharmacokinetic (PBPK) model to predict and characterize the absorption, distribution, metabolism, and excretion of acetaminophen (APAP) in humans. A PBPK model was created that included pharmacologically and toxicological...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases", "Mathematics" ]
632776
Commercial feasibility of targeting the histone methyltransferase setd8 in cancer: new chemical entities and biomarkers.
Within our ERC CoG grant, RSHEALTH, our group has contributed to the to the preclinical development of chemical inhibitors of the ATR kinase as anticancer agents, that are now in clinical trials by several companies. During the course of our investigations, we also made important advances in developing inhibitors of SE...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Integrative Biology: from Genes and Genomes to Systems" ]
US 201716465452 A
Method for determining treatment parameters via an information carrier
A method performed by one or more devices includes determining an information item indicative of at least one parameter affecting the treatment of a textile with the information item being detected by an information carrier of the textile (220) and/or a cleaning device (230), or a cleaning agent (210) and the textile (...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1007/JHEP11(2016)133
Three Dimensional Mathcal N 4 Linear Quivers And Non Abelian T Duals
In this paper we construct a new Type IIB background with an AdS 4 factor that preserves $$ \mathcal{N}=4 $$ Supersymmetry. This solution is obtained using a non-Abelian T-duality transformation on the Type IIA reduction of the AdS 4 × S 7 background. We interpret our configuration as a patch of a more general back...
[ "Fundamental Constituents of Matter", "Mathematics" ]
10.1051/0004-6361/201731667
The Alma Pils Survey Isotopic Composition Of Oxygen Containing Complex Organic Molecules Toward Iras 16293 2422B
This paper presents a systematic survey of the deuterated and 13C isotopologues of a variety of oxygen-bearing complex organic molecules on Solar System scales toward the protostar IRAS 16293-2422B. We use the data from an unbiased molecular line survey between 329 and 363 GHz from the Atacama Large Millimeter/submilli...
[ "Physical and Analytical Chemical Sciences", "Universe Sciences" ]
853387
Phase map of dynamic, adaptive colloidal crystals far from equilibrium
We recently reported the first observation of dynamic adaptive colloidal crystals exhibiting characteristics similar to those commonly associated with living organisms: self-replication, self-healing, adaptation, competition, motility. Here, I propose to do the first experiments to clarify precisely how dynamic adaptiv...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
284331
Dynamic Structural Corporate Finance: Linking Theory and Empirical Testing
There are three components to this project: Theory; Empirical Testing; and Dissemination. All components are linked to the current policy question of how taxes influence debt and systemic risk, and all use novel dynamic structural models. I am unique in explicitly linking such models to empirical testing. Theory: “Lear...
[ "Individuals, Markets and Organisations" ]
10.1161/CIRCULATIONAHA.114.014822
Pentraxin 3 induces vascular endothelial dysfunction through a P-selectin/matrix metalloproteinase-1 pathway
Background - Pentraxin 3 (PTX3), the prototype of long pentraxins, has been described to be associated with endothelial dysfunction in different cardiovascular disorders. No study has yet evaluated the possible direct effect of PTX3 on vascular function. Methods and Results - Through in vitro experiments of vascular re...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2034530130
Shearer Shaft Roundness Error of Signal Processing
For the measurement of shearer shaft geometry signal contain the axis of rotation error and the measurement error, made of two separate programs from shearer shaft the geometric method of measuring signal acquisition and signal processing error. The program is based on the analysis of the shearer shaft Two-point method...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1002/cphc.201300694
Lifetime shortening and fast energy-tansfer processes upon dimerization of a A-π-D-π-A molecule
Time-resolved fluorescence and transient absorption experiments uncover a distinct change in the relaxation dynamics of the homo-dimer formed by two 2,5-bis[1-(4-N-methylpyridinium)ethen-2-yl)]-N-methylpyrrole ditriflate (M) units linked by a short alkyl chain when compared to that of the monomer M. Fluorescence decay...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1007/978-3-319-42417-0_32
Towards A Synthetic Tutor Assistant The Easel Project And Its Architecture
Robots are gradually but steadily being introduced in our daily lives. A paramount application is that of education, where robots can assume the role of a tutor, a peer or simply a tool to help learners in a specific knowledge domain. Such endeavor posits specific challenges: affective social behavior, proper modelling...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
US 0216859 W
IMPROVED CELLULAR CUSHION VEHICLE SEAT SYSTEM
An improved vehicle seat assembly (20) for mounting on the frame (F) of a vehicle driver's seat (s) including a polymer support plate (22) attached to the frame, a polyurethane foam base (24) on the support, an inflatable air cell cushion (26) on the base and an elastic cover (28). The inflatable air cell cushion (26) ...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1038/ncomms7243
A cnidarian homologue of an insect gustatory receptor functions in developmental body patterning
Insect gustatory and odorant receptors (GRs and ORs) form a superfamily of novel transmembrane proteins, which are expressed in chemosensory neurons that detect environmental stimuli. Here we identify homologues of GRs (Gustatory receptor-like (Grl) genes) in genomes across Protostomia, Deuterostomia and non-Bilateria....
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1021/ac303005g
Well-defined microapertures for ion channel biosensors
Gated ion channels are excitable nanopores in biological membranes. They sense and respond to different triggers in nature. The sensory characteristics of these channels can be modified by protein engineering tools and the channels can be functionally reconstituted into synthetic lipid bilayer membranes. The combinatio...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Materials Engineering", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1038/ncomms12354
Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming
Erasure of epigenetic memory is required to convert somatic cells towards pluripotency. Reactivation of the inactive X chromosome (Xi) has been used to model epigenetic reprogramming in mouse, but human studies are hampered by Xi epigenetic instability and difficulties in tracking partially reprogrammed iPSCs. Here we ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1107/S1600576717012882
Improved Orientation Sampling For Indexing Diffraction Patterns Of Polycrystalline Materials
Orientation mapping is a widely used technique for revealing the microstructure of a polycrystalline sample. The crystalline orientation at each point in the sample is determined by analysis of the diffraction pattern, a process known as pattern indexing. A recent development in pattern indexing is the use of a brute-f...
[ "Condensed Matter Physics", "Computer Science and Informatics" ]
10.1186/1745-6150-7-6
Amino Acid Fermentation At The Origin Of The Genetic Code
There is evidence that the genetic code was established prior to the existence of proteins, when metabolism was powered by ribozymes. Also, early proto-organisms had to rely on simple anaerobic bioenergetic processes. In this work I propose that amino acid fermentation powered metabolism in the RNA world, and that this...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1088/1361-6463/aad520
Magnons versus electrons in thermal spin transport through metallic interfaces
We develop a theory for spin transport in magnetic metals that treats the contribution of magnons and electrons on equal footing. As an application, we consider thermally-driven spin injection across an interface between a magnetic metal and a normal metal, i. e. the spin-dependent Seebeck effect. We show that the rat...
[ "Condensed Matter Physics" ]
10.1021/acs.nanolett.5b01461
Efficient Production of Single-Stranded Phage DNA as Scaffolds for DNA Origami
Scaffolded DNA origami enables the fabrication of a variety of complex nanostructures that promise utility in diverse fields of application, ranging from biosensing over advanced therapeutics to metamaterials. The broad applicability of DNA origami as a material beyond the level of proof-of-concept studies critically d...
[ "Synthetic Chemistry and Materials", "Materials Engineering", "Biotechnology and Biosystems Engineering" ]
10.1007/978-3-662-53354-3_6
The Big Match In Small Space
We study repeated games with absorbing states, a type of two-player, zero-sum concurrent mean-payoff games with the prototypical example being the Big Match of Gillete (1957). These games may not allow optimal strategies but they always have \(\varepsilon \)-optimal strategies. In this paper we design \(\varepsilon \)-...
[ "Mathematics", "Computer Science and Informatics" ]
10.1007/JHEP06(2015)101
Two Wave Functions And Ds Cft On S 1 S 2
We evaluate the tunneling and Hartle-Hawking wave functions on S 1 � S 2 boundaries in Einstein gravity with a positive cosmological constant. In the large over- all volume limit the classical predictions of both wave functions include an ensemble of Schwarzschild-de Sitter black holes. We show that the Hartle-Hawking ...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
10.1016/j.msea.2015.08.031
Effect of grain size on compressive behaviour of titanium at different strain rates
An investigation was conducted to evaluate the dependence on grain size of the compressive deformation of commercial purity (CP) Ti. Tests were performed at room temperature using grain sizes from coarse-grained CG (20μm) to ultrafine-grained UFG (500nm) and nanocrystalline NC (90nm) with testing strain rates in the ra...
[ "Condensed Matter Physics", "Materials Engineering" ]
EP 18000437 A
PREPACKAGED CHARGE FOR THE PREPARATION OF BEVERAGES
Prepackaged charge of edible material for the preparation of beverages, comprising a vessel container body (1, 101) provided, at the open end (111), with a sealing wall made of airtight material and provided on the bottom wall (201, 211) with the dispensing means (221) of the prepared beverage, being provided a second ...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1093/sysbio/syz066
Continued Adaptation of C4 Photosynthesis After an Initial Burst of Changes in the Andropogoneae Grasses
C$_{4}$ photosynthesis is a complex trait that sustains fast growth and high productivity in tropical and subtropical conditions and evolved repeatedly in flowering plants. One of the major C$_{4}$ lineages is Andropogoneae, a group of $\sim $1200 grass species that includes some of the world’s most important crops and...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1103/PhysRevB.91.195403
Aggregation and electronically induced migration of oxygen vacancies in TiO2 anatase
The influence of the electric field and electric current on the behavior of oxygen vacancies (VOs) in TiO2 anatase was investigated with scanning tunneling microscopy (STM). At the anatase (101) surface VOs are not stable; they migrate into the bulk at temperatures above 200 K. Scanning a clean anatase (101) surface a...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
10.1364/OE.21.025954
Performance And Capacity Analysis Of Poisson Photon Counting Based Iter Pic Ocdma Systems
In this paper, an iterative parallel interference cancellation (Iter-PIC) technique is developed for optical code-division multiple-access (OCDMA) systems relying on shot-noise limited Poisson photon-counting reception. The novel semi-analytical tool of extrinsic information transfer (EXIT) charts is used for analysing...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1016/j.tig.2012.03.009
The genomics of speciation-with-gene-flow
The emerging field of speciation genomics is advancing our understanding of the evolution of reproductive isolation from the individual gene to a whole-genome perspective. In this new view it is important to understand the conditions under which 'divergence hitchhiking' associated with the physical linkage of gene regi...
[ "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution" ]
10.2514/6.2014-0709
Optimal Control Of Wind Farm Power Extraction In Large Eddy Simulations
In the present work we couple flow simulations performed using Large Eddy Simulations (LES) with gradient based optimization to control individual turbine in a farm, so as to achieve an increase in the total power output. The controls in our optimization problem are the disk-based thrust coefficients C′ T,n of individu...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
interreg_1288
Energy Vision 2020 for South East European Cities 
The need to improve resource efficiency is at the heart of the EU agenda. This is evidenced both by the energy and pollution targets set, as well as the Resource-Efficient Europe flagship initiative, within the Europe 2020 strategy. In many countries win South East Europe, the energy intensity of countries is among the...
[ "Products and Processes Engineering", "Earth System Science", "Institutions, Governance and Legal Systems" ]
10.1039/C9TC00082H
N B P Al As And Ga Graphdiyne Graphyne Lattices First Principles Investigation Of Mechanical Optical And Electronic Properties
Graphdiyne and graphyne are carbon-based two-dimensional (2D) porous atomic lattices with outstanding physics and excellent application prospects for advanced technologies, like nanoelectronics and energy storage systems. During the last few years, B- and N-graphdiyne nanomembranes were experimentally realized. Motivat...
[ "Condensed Matter Physics", "Synthetic Chemistry and Materials", "Materials Engineering" ]
10.1098/rsbl.2016.0876
Capturing goats: documenting two hundred years of mitochondrial DNA diversity among goat populations from Britain and Ireland
The domestic goat ( Capra hircus ) plays a key role in global agriculture, being especially prized in regions of marginal pasture. However, the advent of industrialized breeding has seen a dramatic reduction in genetic diversity within commercial populations, while high extinction rates among fe...
[ "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution" ]
10.1371/journal.pcbi.1004445
Task-Driven Activity Reduces the Cortical Activity Space of the Brain: Experiment and Whole-Brain Modeling
How a stimulus or a task alters the spontaneous dynamics of the brain remains a fundamental open question in neuroscience. One of the most robust hallmarks of task/stimulus-driven brain dynamics is the decrease of variability with respect to the spontaneous level, an effect seen across multiple experimental conditions ...
[ "Neuroscience and Disorders of the Nervous System", "Computer Science and Informatics" ]
788203
Innovation and opportunity in the evolution of life
The aim is to produce a complete evolutionary tree of tetrapods and use this to explore two core questions in macroevolution: the balance between innovation and external processes in driving the evolution of life; and, identifying the best model for morphological evolution. Biodiversity today is unbalanced, with a smal...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems", "Computer Science and Informatics" ]
10.1002/anie.201404568
Membrane deformation by neolectins with engineered glycolipid binding sites
Lectins are glycan-binding proteins that are involved in the recognition of glycoconjugates at the cell surface. When binding to glycolipids, multivalent lectins can affect their distribution and alter membrane shapes. Neolectins have now been designed with controlled number and position of binding sites to decipher th...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1039/C3SC50496D
Charge Carrier Trapping Recombination And Transfer In Hematite Α Fe2O3 Water Splitting Photoanodes
Hematite is currently considered one of the most promising materials for the conversion and storage of solar energy via the photoelectrolysis of water. Whilst there has been extensive research and much progress in the development of hematite structures with enhanced photoelectrochemical (PEC) activity, relatively limit...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1021/ja501458s
Turn-on phosphorescence by metal coordination to a multivalent terpyridine ligand: A new paradigm for luminescent sensors
A hexathiobenzene molecule carrying six terpyridine (tpy) units at the periphery has been designed to couple the aggregation induced phosphorescence, displayed by the core in the solid state, to the metal binding properties of the tpy units. Upon Mg2+ complexation in THF solution, phosphorescence of the hexathiobenzene...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1002/wcs.1194
Blindsight: Recent and historical controversies on the blindness of blindsight
The phenomenon 'blindsight' has received much interest from neuroscientists, philosophers, and psychologists during the last decades. Several researchers seem to agree that blindsight might be of great importance in the ambition to find neural correlates of consciousness. However, the history of blindsight is a history...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.5194/amt-11-1207-2018
Interlaboratory comparison of <i>δ</i><sup>13</sup>C and <i>δ</i>D measurements of atmospheric CH<sub>4</sub> for combined use of data sets from different laboratories
Abstract. We report results from a worldwide interlaboratory comparison of samples among laboratories that measure (or measured) stable carbon and hydrogen isotope ratios of atmospheric CH4 (δ13C-CH4 and δD-CH4). The offsets among the laboratories are larger than the measurement reproducibility of individual laboratori...
[ "Earth System Science", "Physical and Analytical Chemical Sciences" ]
10.1088/0004-637X/743/2/143
Testing Scaling Relations For Solar Like Oscillations From The Main Sequence To Red Giants Using Kepler Data
We have analyzed solar-like oscillations in ~1700 stars observed by the Kepler Mission, spanning from the main sequence to the red clump. Using evolutionary models, we test asteroseismic scaling relations for the frequency of maximum power (νmax), the large frequency separation (Δν), and oscillation amplitudes. We show...
[ "Universe Sciences" ]
10.1007/s10853-012-7061-3
Evolution of microhardness and microstructure in a cast Al-7 % Si alloy during high-pressure torsion
Disks of a cast Al-7 % Si alloy were processed through high-pressure torsion (HPT) for 1/4, 1/2, 1, 5, and 10 revolutions under a pressure of 6. 0 GPa and at temperatures of 298 and 445 K. The hardness of the samples after processing was significantly higher than in the cast sample, and the hardness profiles across th...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1145/2470654.2466474
Indoor Weather Stations Investigating A Ludic Approach To Environmental Hci Through Batch Prototyping
In this project, we investigated how a ludic approach might open new possibilities for environmental HCI by designing three related devices that encourage environmental awareness while eschewing utilitarian or persuasive agendas. In addition, we extended our methodological approach by batch-producing multiple copies of...
[ "Computer Science and Informatics", "Environmental Biology, Ecology and Evolution", "Products and Processes Engineering" ]
10.1126/science.1201578
A midzone-based ruler adjusts chromosome compaction to anaphase spindle length
Partitioning of chromatids during mitosis requires that chromosome compaction and spindle length scale appropriately with each other. However, it is not clear whether chromosome condensation and spindle elongation are linked. Here, we find that yeast cells could cope with a 45% increase in the length of their longest c...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
278410
From correct to high-quality reactive systems
Formal verification is the study of algorithms and tools for the development of correct hardware and software designs. Two fundamental problems in formal verification are temporal logic model checking -- given a mathematical model of the system and a temporal-logic formula that specifies the desired behavior of the sys...
[ "Computer Science and Informatics" ]
W2014616114
Slavery, Settlement, and Empire: The Expansion and Growth of Slavery in the Interior of the North American Continent, 1770-1820
The expansion of slavery on the North American continent under the newly independent United States was both remarkable and unprecedented. In 1770, European settlers, European empires, and African American slaves had only the barest presence west of the Appalachians. While scattered settlements of European Americans hel...
[ "The Study of the Human Past", "The Social World and Its Interactions", "Human Mobility, Environment, and Space" ]
W2067518790
Selective removal of carious human dentin using a nanosecond pulsed laser operating at a wavelength of 5.85 μ m
Less invasive methods for treating dental caries are strongly desired. However, conventional dental lasers do not always selectively remove caries or ensure good bonding to the composite resin. According to our previous study, demineralized dentin might be removed by a nanosecond pulsed laser operating at wavelengths o...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
10.1096/fj.201500128
Skeletal muscle PGC-1α modulates systemic ketone body homeostasis and ameliorates diabetic hyperketonemia in mice
Ketone bodies (KBs) are crucial energy substrates during states of low carbohydrate availability. However, an aberrant regulation of KB homeostasis can lead to complications such as diabetic ketoacidosis. Exercise and diabetes affect systemic KB homeostasis, but the regulation of KB metabolism is still enigmatic. In ou...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1063/1.4745479
Tuning Effective Interactions Close To The Critical Point In Colloidal Suspensions
We report a numerical investigation of two colloids immersed in a critical solvent, with the aim of quantifying the effective colloid-colloid interaction potential. By turning on an attraction between the colloid and the solvent particles we follow the evolution from the case in which the solvent density close to the c...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
W3081688436
Socio-Economic Factors as a Criterion for the Classification of Housing Markets in Selected Cities in Poland
Abstract Property prices, including, in particular, residential properties, vary across local markets. For example, according to the National Bank of Poland, in late 2018, the average unit price of an apartment on the secondary market stood at PLN 8,700 in Warsaw, 6,100 in Poznań, 4,800 in Szczecin, and 3,800 in Kielce...
[ "Individuals, Markets and Organisations", "Human Mobility, Environment, and Space" ]
10.1002/anie.201509910
Monitoring Backbone Hydrogen-Bond Formation in β-Barrel Membrane Protein Folding
β-barrel membrane proteins are key components of the outer membrane of bacteria, mitochondria and chloroplasts. Their three-dimensional structure is defined by a network of backbone hydrogen bonds between adjacent β-strands. Here, we employ hydrogen-deuterium (H/D) exchange in combination with NMR spectroscopy and mass...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1080/17508487.2019.1650382
Conflicting Framings Young Ghanaians And Dutch Education Professionals Views On The Impact Of Mobility On Education
This paper investigates how Dutch education professionals and Ghanaian migrant youth frame the impact of young people’s geographical mobility on education. The paper is based on a discourse analysi. . .
[ "Human Mobility, Environment, and Space", "The Social World and Its Interactions" ]
10.1557/mrs.2015.258
Composite epitaxial thin films: A new platform for tuning, probing, and exploiting mesoscale oxides
Abstract
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1016/j.chemgeo.2017.11.037
Accurate stable tungsten isotope measurements of natural samples using a <sup>180</sup>W-<sup>183</sup>W double-spike
Tungsten is a moderately siderophile element and, thus, enriched in the Earth's core. Moreover, W behaves incompatibly during partial melting, causing relative enrichment in the Earth's crust compared to the mantle. However, little is known about the geochemical cycle of the redox-sensitive element W in the crust-mantl...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
10.1167/iovs.12-10672
Adaptive optics imaging of geographic atrophy
PURPOSE. To report the findings of en face adaptive optics (AO) near infrared (NIR) reflectance fundus flood imaging in eyes with geographic atrophy (GA). METHODS. Observational clinical study of AO NIR fundus imaging was performed in 12 eyes of nine patients with GA, and in seven controls using a flood illumination ca...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
W2106249147
Betti Numbers of Transversal Monomial Ideals
In this paper, by a modification of a previously constructed minimal free resolution for a transversal monomial ideal, the Betti numbers of this ideal is explicitly computed. For convenient characteristics of the ground field, up to a change of coordinates, the ideal of t-minors of a generic pluri-circulant matrix is a...
[ "Mathematics" ]
10.1007/s10750-016-2921-5
Singing above the chorus: cooperative Princess cichlid fish (Neolamprologus pulcher) has high pitch
Teleost fishes not only communicate with well-known visual cues, but also olfactory and acoustic signals. Communicating with sound has advantages, as acoustic signals propagate fast, omnidirectionally, around obstacles and over long distances. Heterogeneous environments might favour multimodal communication, especially...
[ "Environmental Biology, Ecology and Evolution", "Condensed Matter Physics" ]
10.1093/mnras/stz2721
Young star cluster populations in the E-MOSAICS simulations
ABSTRACT We present an analysis of young star clusters (YSCs) that form in the E-MOSAICS cosmological, hydrodynamical simulations of galaxies and their star cluster populations. Through comparisons with observed YSC populations, this work aims to test models for YSC formation and obtain an insight into the formation pr...
[ "Universe Sciences", "Computer Science and Informatics" ]
W1512987951
The Swedish version of the Insomnia Severity Index: Factor structure analysis and psychometric properties in chronic pain patients
Abstract Objective Insomnia is the most commonly diagnosed comorbidity disorder among patients with chronic pain. This circumstance requests brief and valid instruments for screening insomnia in epidemiological studies. The main object of this study was to assess the psychometric properties and factor structure of the ...
[ "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases", "The Human Mind and Its Complexity" ]
W2623823751
Environmentally friendly parametric alarm for alerting marine mammals of approaching vessels
Marine mammals are vulnerable to boat, barge, and ship collisions. Although more commonly identified and reported in busy coastal areas, collisions are not restricted to shipping lanes or shallow water environments. A common denominator is that they all occur near the surface. Here the acoustical laws of reflection and...
[ "Environmental Biology, Ecology and Evolution", "Products and Processes Engineering", "Condensed Matter Physics" ]
W1987228444
A Macroeconomic Structure of Employment: Rural-Urban Conflict in a Kaleckian Framework
Faced with the phenomenon of “jobless growth” and to contain the vast “surplus population” the governments of the developing world have taken up measures to manage poverty and social security outside the sphere of accumulation-led growth in the “urban-modern” sector especially through “rural” employment generation. Man...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems" ]
10.1038/s41588-019-0350-x
Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases
Microbiome-wide association studies on large population cohorts have highlighted associations between the gut microbiome and complex traits, including type 2 diabetes (T2D) and obesity 1 . However, the causal relationships remain largely unresolved. We leveraged information from 952 normoglycemic individuals for whom g...
[ "Integrative Biology: from Genes and Genomes to Systems", "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1007/s00041-011-9206-1
Ridgelet-type Frame Decompositions for Sobolev Spaces related to Linear Transport
In this paper we study stability properties of ridgelet and curvelet frames for mixed-smoothness Sobolev spaces with norm {double pipe} f {double pipe} s = {double pipe} f {double pipe} L2(ℝ d) + {double pipe} s. ∇ f {double pipe} L2(ℝ d). Here s ∈ S d-1 is a transport direction and ∇ denotes the gradient of f. Such ...
[ "Mathematics" ]
10.1093/cercor/bhr214
In vivo imaging and noninvasive ablation of pyramidal neurons in adult NEX-CreERT2 mice
To study the function of individual neurons that are embedded in a complex neural network is difficult in mice. Conditional mutagenesis permits the spatiotemporal control of gene expression including the ablation of cells by toxins. To direct expression of a tamoxifen-inducible variant of Cre recombinase (CreERT2) sele...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1038/s41598-018-36110-y
A near atomic-scale view at the composition of amyloid-beta fibrils by atom probe tomography
Amyloid-beta (Ab) proteins play an important role in a number of neurodegenerative diseases. Ab is found in senile plaques in brains of Alzeimer’s disease patients. The 42 residues of the monomer form dimers which stack to fibrils gaining several micrometers in length. Using Ab fibrils with 13C and 15N marker substitut...
[ "Physical and Analytical Chemical Sciences", "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1007/978-3-662-55665-8_15
Doing Without Nature
We show that every indeterministic n-agent choice model \(M^i\) can be transformed into a deterministic n-agent choice model \(M^d\), such that \(M^i\) is a bounded morphic image of \(M^d\). This generalizes an earlier result from Van Benthem and Pacuit [16] about finite two-player choice models. It further strengthens...
[ "Computer Science and Informatics", "Mathematics" ]
10.1261/rna.047324.114
Unexpected selection to retain high GC content and splicing enhancers within exons of multiexonic IncRNA loci
If sequencing was possible only for genomes, and not for RNAs or proteins, then functional protein-coding exons would be recognizable by their unusual patterns of nucleotide composition, specifically a high GC content across the body of exons, and an unusual nucleotide content near their edges. RNAs and proteins can, o...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1371/journal.pone.0190101
Complex patterns of concomitant medication use: A study among Norwegian women using paracetamol during pregnancy
Background Studies on medication safety in pregnancy often rely on an oversimplification of medication use into exposed or non-exposed, without considering intensity and timing of use in pregnancy, or concomitant medication use. This study uses paracetamol in pregnancy as the motivating example to introduce a method of...
[ "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1007/s10578-016-0642-7
The Effects of Intranasal Oxytocin Administration on Sensitive Caregiving in Mothers with Postnatal Depression
Postnatal depression (PND) is common and negatively affects the mother–infant relationship; oxytocin (OT) has been found to have positive effects on parenting, although psychiatric disorders may reduce these effects. Thus, we explored the role of OT in mothers diagnosed with PND. A within-subject, randomized controlled...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
W2954070110
A practical guide to intelligent image-activated cell sorting
Intelligent image-activated cell sorting (iIACS) is a machine-intelligence technology that performs real-time intelligent image-based sorting of single cells with high throughput. iIACS extends beyond the capabilities of fluorescence-activated cell sorting (FACS) from fluorescence intensity profiles of cells to multidi...
[ "Products and Processes Engineering", "Cell Biology, Development, Stem Cells and Regeneration", "Computer Science and Informatics" ]
10.1007/s42979-020-00325-6
The FaceChannel: A Fast and Furious Deep Neural Network for Facial Expression Recognition
Current state-of-the-art models for automatic facial expression recognition (FER) are based on very deep neural networks that are effective but rather expensive to train. Given the dynamic conditions of FER, this characteristic hinders such models of been used as a general affect recognition. In this paper, we address ...
[ "Computer Science and Informatics" ]
10.1088/1367-2630/19/1/013027
Entanglement And Extreme Spin Squeezing Of Unpolarized States
We present criteria to detect the depth of entanglement in macroscopic ensembles of spin-j particles using the variance and second moments of the collective spin components. The class of states detected goes beyond traditional spin-squeezed states by including Dicke states and other unpolarized states. The criteria der...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
EP 07290701 A
Noise-reduction device for automobile air-conditioning circuit, conduit and circuit comprising same
The conduit has a noise reducer device (607) in its internal space and mounted to contact a wall of the conduit. The device has geometry of a tubular part delimited by two transversal inlet and outlet faces (608, 609) for fluid and by an external radial face (610) which connects the inlet and outlet faces. The inlet an...
[ "Products and Processes Engineering", "Materials Engineering" ]
W4319773907
Faire sa jeunesse dans les rues de Ouagadougou
À Ouagadougou, les jeunes hommes qui vivent et dorment dans les rues s’appellent les bakoroman. Mais le plus souvent, et bien qu’ils n’aiment pas ça, on les appelle les « enfants de la rue ». Par le vol, la mendicité et les petits boulots, les bakoroman s’insèrent dans différentes niches de l’économie urbaine qui leur ...
[ "The Social World and Its Interactions", "Human Mobility, Environment, and Space" ]
interreg_3927
Road of Alpine Vineyard
Before the imposition of borders between France and Italy, Mountains of Turin, Val d’Aosta and Savoy was deeply interconnected. On both sides of the Alpes, vineyard was cultivated. Selected grape varieties and adapted to these climatic conditions was exchanged thanks to the trade flux and travellers. The common histor...
[ "Human Mobility, Environment, and Space", "The Study of the Human Past", "Studies of Cultures and Arts" ]
10.1038/emboj.2013.211
How unfinished business from S-phase affects mitosis and beyond
The eukaryotic cell cycle is conventionally viewed as comprising several discrete steps, each of which must be completed before the next one is initiated. However, emerging evidence suggests that incompletely replicated, or unresolved, chromosomes from S-phase can persist into mitosis, where they present a potential th...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
US 0107004 W
OILWELL CASING ELECTRICAL POWER PICK-OFF POINTS
A power supply apparatus is provided for supplying power and communications within a first piping structure. An external power transfer device (42) is positioned around the first piping structure (24) and is magnetically coupled to an internal power transfer device (44). The internal power transfer device (44) is posit...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1002/hlca.201600122
Phenylazide Hybrid-Silica – Polarization Platform for Dynamic Nuclear Polarization at Cryogenic Temperatures
Hyperpolarization of NMR-active nuclei is key to gather high quality spectra of rare species and insensitive isotopes. We have recently established that silica-based materials containing regularly distributed nitroxyl radicals connected to the silica matrix by flexible linkers can serve as promising polarization matric...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1016/j.bpj.2012.11.3837
Amphipathic lipid packing sensor motifs: Probing bilayer defects with hydrophobic residues
Sensing membrane curvature allows fine-tuning of complex reactions that occur at the surface of membrane-bound organelles. One of the most sensitive membrane curvature sensors, the Amphipathic Lipid Packing Sensor (ALPS) motif, does not seem to recognize the curved surface geometry of membranes per se; rather, it recog...
[ "Condensed Matter Physics", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
643616
Electrochemical-Mediated site-selective halogenation of phenol as a platform for accessing poly-substituted arenes.
ElectroPheX aims to develop electrochemically-mediated methods for the site-selective halogenation of phenols. Electrochemistry will be the main feature of this project as it can be an efficient way to access and manipulate reactive intermediates. The project will span disciplines (interdisciplinarity) and aims to stu...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
W2100465390
The agrifood system policy agenda and research domain
Abstract In the US, traditionally food policy has been considered a federal concern dealing with issues such as nutrition, anti-hunger, food safety, food labeling, international trade and food aid. In the 1970s, new concerns arose about the potentially deleterious consequences of the modern global food system. Social m...
[ "The Social World and Its Interactions", "Institutions, Governance and Legal Systems" ]
interreg_2979
Restructuring Cultural Landscapes
Industrial processes, such as mining, have altered and disturbed landscapes within a short time. Natural and cultural heritages as well as regional identities have often been neglected by changing economic structures. REKULA, the Restructuring of Cultural Landscapes, aims at establishing integrated and co-ordinated mea...
[ "Earth System Science", "Human Mobility, Environment, and Space", "Studies of Cultures and Arts" ]
10.1109/CVPR.2017.267
Dsac Differentiable Ransac For Camera Localization
RANSAC is an important algorithm in robust optimization and a central building block for many computer vision applications. In recent years, traditionally hand-crafted pipelines have been replaced by deep learning pipelines, which can be trained in an end-to-end fashion. However, RANSAC has so far not been used as part...
[ "Computer Science and Informatics" ]
10.1093/bib/bbx160
Community effort endorsing multiscale modelling, multiscale data science and multiscale computing for systems medicine
Systems medicine holds many promises, but has so far provided only a limited number of proofs of principle. To address this road block, possible barriers and challenges of translating systems medicine into clinical practice need to be identified and addressed. The members of the European Cooperation in Science and Tech...
[ "Integrative Biology: from Genes and Genomes to Systems", "Computer Science and Informatics", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.5194/amt-8-1447-2015
Cross-validation of IASI/MetOp derived tropospheric δD with TES and ground-based FTIR observations
Abstract. The Infrared Atmospheric Sounding Interferometer (IASI) flying onboard MetOpA and MetOpB is able to capture fine isotopic variations of the HDO to H2O ratio (δD) in the troposphere. Such observations at the high spatio-temporal resolution of the sounder are of great interest to improve our understanding of th...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
US 202318518052 A
WORKING MACHINE
A floor mat arranged in a working machine includes a floor portion, a wall portion arranged on a circumferential portion of the floor portion, and an opening portion arranged on a part of a connecting portion of the wall portion, the connecting portion connecting to the floor portion. The floor mat includes a mat main ...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1109/CDC.2016.7799334
Polarization In Coopetitive Networks Of Heterogeneous Nonlinear Agents
The mechanisms of regular cooperative behavior in multi-agent networks, such as consensus and synchronization, have been thoroughly studied. However, many natural and engineered networks do not synchronize, exhibiting persistent disagreement or clustering. One of the reasons for this “irregular” behavior is competition...
[ "Mathematics", "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.3389/fimmu.2017.01115
Factor XII-driven inflammatory reactions with implications for anaphylaxis
Anaphylaxis is a life-threatening allergic reaction. It is triggered by the release of pro-inflammatory cytokines and mediators from mast cells and basophils in response to immunologic or non-immunologic mechanisms. Mediators that are released upon mast cell activation include the highly sulfated polysaccharide and ino...
[ "Immunity, Infection and Immunotherapy", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.3389/fimmu.2012.00313
The intestinal B-cell response in celiac disease
The function of intestinal immunity is to provide protection toward pathogens while preserving the composition of the microflora and tolerance to orally fed nutrients. This is achieved via a number of tightly regulated mechanisms including production of IgA antibodies by intestinal plasma cells. Celiac disease is a com...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
Q2694084
Working capital support for JG Group sp. z o.o.
The project concerns support to the entrepreneur in providing liquidity and support to day-to-day activities due to the financial difficulties that have occurred to the entrepreneur as a result of the COVID-19 outbreak. Financial assistance under scheme SA.57015 (2020/N)
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems" ]
W2367497198
Correction model for flow calculation of plain river network
Complex water movement and fewer measuring points are the unfavorable factors in improving the accuracy of flow calculation of river networks.For this reason,a correction model for a plain river network was developed based on the three-step method in dealing with the water levels at key nodes of a looping river network...
[ "Earth System Science", "Products and Processes Engineering" ]
AU 2020/367246 A
Method for obtaining material from plant cell surfaces
The invention relates to a method for detaching expressed material from the surface or the apoplast of plant cells, the plant cells being treated in a liquid medium using a rotor-stator. The specific heat of the rotor-stator introduced by the rotation of the stator is at most 3 kJ per kg of the liquid medium and per g/...
[ "Materials Engineering", "Biotechnology and Biosystems Engineering" ]
307442
Tailoring Material Properties Using Femtosecond Lasers: A New Paradigm for Highly Integrated Micro-/Nano- Scale Systems
Using recent progress in laser technology and in particular in the field of ultra-fast lasers, we are getting close to accomplish the alchemist dream of transforming materials. Compact lasers can generate pulses with ultra-high peak powers in the Tera-Watt or even Peta-Watt ranges. These high-power pulses lead to a rad...
[ "Materials Engineering", "Condensed Matter Physics", "Synthetic Chemistry and Materials" ]
W1979600830
A study on the presence of flagella in the order Rickettsiales: the case of ‘Candidatus Midichloria mitochondrii’
According to Bergey's Manual of Systematic Bacteriology, the Rickettsiales are '…bacteria with typical gram-negative cell walls and no flagella'. The recently sequenced genome of 'Candidatus Midichloria mitochondrii', a divergent lineage within the order Rickettsiales capable of invading mitochondria in ixodid ticks, r...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1101/2020.01.29.924373
Variable Environments Select For Short Lifespan
Abstract The role of environmental variation in the evolution of lifespan is contested. Classic theory suggests that variable environments result in evolution of long life but novel theoretical breakthroughs show that environmental variation can instead select for short lifespan when the changes are rapid relative to g...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1039/c5cp00582e
How exciton-vibrational coherences control charge separation in the photosystem II reaction center
Two-dimensional photon echo in the photosystem II reaction center reveals the exciton-vibrational coherences that promote directed energy/electron transfers.
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1080/24694452.2020.1740579
Expanding The Boundaries Of Justice In Urban Greening Scholarship Toward An Emancipatory Antisubordination Intersectional And Relational Approach
Supported by a large body of scholarship, it is increasingly orthodox practice for cities to deploy urban greening interventions to address diverse socioenvironmental challenges, from protecting ur. . .
[ "The Social World and Its Interactions", "Human Mobility, Environment, and Space", "Environmental Biology, Ecology and Evolution" ]
172592
Metrology for future 3d-technologies
Within the food chain of equipment delivery for the semiconductor industry, Europe has kept a very strong position in the metrology area with many companies establishing themselves as main leaders in the field. Hence in line with the objectives of the ICT25 call for innovation action to overcome the (initial) barriers...
[ "Materials Engineering", "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
221173
Seeing things you don't see: unifying the philosophy, psychology and neuroscience of multimodal mental imagery
When I am looking at my coffee machine that makes funny noises, this is an instance of multisensory perception – I perceive this event by means of both vision and audition. But very often we only receive sensory stimulation from a multisensory event by means of one sense modality. If I hear the noisy coffee machine in ...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]