id
stringlengths
6
42
title
stringlengths
3
499
abstract
stringlengths
0
6.24k
label
listlengths
0
6
10.1088/0034-4885/79/4/046902
Cosmological Tests Of Modified Gravity
We review recent progress in the construction of modified gravity models as alternatives to dark energy as well as the development of cosmological tests of gravity. Einstein's theory of General Relativity (GR) has been tested accurately within the local universe i. e. the Solar System, but this leaves the possibility ...
[ "Universe Sciences", "Fundamental Constituents of Matter" ]
10.15252/msb.20167449
High-throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae
Genome-wide screens have discovered a large set of essential genes in the opportunistic human pathogen Streptococcus pneumoniae. However, the functions of many essential genes are still unknown, hampering vaccine development and drug discovery. Based on results from transposon sequencing (Tn-seq), we refined the list o...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1111/nph.13852
Viral infection of the marine alga Emiliania huxleyi triggers lipidome remodeling and induces the production of highly saturated triacylglycerol
Viruses that infect marine photosynthetic microorganisms are major ecological and evolutionary drivers of microbial food webs, estimated to turn over more than a quarter of the total photosynthetically fixed carbon. Viral infection of the bloom-forming microalga Emiliania huxleyi induces the rapid remodeling of host pr...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering" ]
641402
Machine learning for scalable meteorology and climate
To develop Europe’s computer architecture of the future, MAELSTROM will co-design bespoke compute system designs for optimal application performance and energy efficiency, a software framework to optimise usability and training efficiency for machine learning at scale, and large-scale machine learning applications for ...
[ "Computer Science and Informatics", "Earth System Science" ]
10.1109/ICASSP.2019.8682709
Light Field Denoising Using 4D Anisotropic Diffusion
In this paper, we present a novel light field denoising algorithm using a vector-valued regularization operating in the 4D ray space. More precisely, the method performs a PDE-based anisotropic diffusion along directions defined by local structures in the 4D ray space. It does not require prior estimation of disparity ...
[ "Computer Science and Informatics", "Mathematics" ]
10.1029/2012GC004086
Modeling Evolution Of The San Andreas Fault System In Northern And Central California
[1] We present a three-dimensional finite element thermomechanical model idealizing the complex deformation processes associated with evolution of the San Andreas Fault system (SAFS) in northern and central California over the past 20 Myr. More specifically, we investigate the mechanisms responsible for the eastward (l...
[ "Earth System Science", "Products and Processes Engineering" ]
W1572263773
Antibacterial Activities of Bacterial Symbionts of Soft Coral Sinularia Sp. against Tuberculosis Bacteria
Tuberculosis (TB) is caused by Mycobacterium tuberculosis. Although TB is a curable disease, it continues to be one of the most important infectious causes of death worldwide. Indonesia ranks 3rd on the list of TB high burden countries in the world with 86,000 cases deaths and the Multi Drug Resistant Tuberculosis (M...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
278469
Simple locally compact groups: exploring the boundaries of the linear world
The theory of locally compact groups stretches out between two antipodes: on one hand, connected groups whose structure, according to the solution to Hilbert fifth problem, is governed by Lie theory and is thus relatively rigid, and on the other hand, discrete groups, which are subject to a spectacular variety of behav...
[ "Mathematics" ]
10.1016/j.sbi.2016.10.004
Structure and elevator mechanism of the Na<sup>+</sup>-citrate transporter CitS
The recently determined crystal structure of the bacterial Na+-citrate symporter CitS provides unexpected structural and mechanistic insights. The protein has a fold that has not been seen in other proteins, but the oligomeric state, domain organization and proposed transport mechanism strongly resemble those of the so...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1161/HYPERTENSIONAHA.113.01428
Target Sequencing Cell Experiments And A Population Study Establish Endothelial Nitric Oxide Synthase Enos Gene As Hypertension Susceptibility Gene
A case-control study revealed association between hypertension and rs3918226 in the endothelial nitric oxide synthase (eNOS) gene promoter (minor/major allele, T/C allele). We aimed at substantiating these preliminary findings by target sequencing, cell experiments, and a population study. We sequenced the 140-kb genom...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Physiology in Health, Disease and Ageing" ]
W4289645539
Clinical, psychological, social, and family characterization of suicidal behavior in Chilean adolescents: a multiple correspondence analysis
Introduction Suicide is the second leading cause of premature death in people between 15 and 29 years old and the third in young people between 15 and 19 years old. Adolescence is a critical period concerning mental health disorders since there is greater vulnerability to suicidal behaviors. The situation in Latin Amer...
[ "The Human Mind and Its Complexity", "Prevention, Diagnosis and Treatment of Human Diseases", "The Social World and Its Interactions" ]
10.1016/j.sbspro.2011.08.061
Effects of energy price fluctuation on car-based individual activity-travel behavior
In the transportation literature, the effects of energy price have been studied primarily in terms of their effects on aspects of travel behaviour, both in the short and long term. In the short term, people may adapt their driving style, departure time, travel mode choice, route choice and/or destination choice. But in...
[ "Individuals, Markets and Organisations", "Human Mobility, Environment, and Space" ]
10.1016/j.evolhumbehav.2016.05.005
Something to talk about: are conversation sizes constrained by mental modeling abilities?
Conversations are ubiquitous and central elements of daily life. Yet a fundamental feature of conversation remains a mystery: It is genuinely difficult to maintain an everyday conversation with more than four speakers. Why? We introduce a “mentalizing explanation” for the conversation size constraint, which suggests th...
[ "The Human Mind and Its Complexity", "The Social World and Its Interactions" ]
10.1016/j.neuropsychologia.2018.12.001
Traces of statistical learning in the brain's functional connectivity after artificial language exposure
Our environment is full of statistical regularities, and we are attuned to learn about these regularities by employing Statistical Learning (SL), a domain-general ability that enables the implicit detection of probabilistic regularities in our surrounding environment. The role of brain connectivity on SL has been previ...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1051/0004-6361/201730552
Gaia Data Release 1 Open Cluster Astrometry Performance Limitations And Future Prospects
Context. The first Gaia Data Release contains the Tycho-Gaia Astrometric Solution (TGAS). This is a subset of about 2 million stars for which, besides the position and photometry, the proper motion and parallax are calculated using Hipparcos and Tycho-2 positions in 1991. 25 as prior information. Aims. We investigate t...
[ "Universe Sciences", "Computer Science and Informatics" ]
10.1021/ol3007937
Photooxidations of 2-(γ,ε-dihydroxyalkyl) furans in water: Synthesis of DE-bicycles of the pectenotoxins
Photooxygenations of 2-(γ,ε-dihydroxyalkyl) furans in H 2O followed by in situ reduction and ketalization affords, in one synthetic operation, DE-bicyclic ketals of the pectenotoxins.
[ "Synthetic Chemistry and Materials" ]
883669
A micro-scale perspective on alpine floras under climate change. Linking observations and models to improve our understanding of the future of European high mountain plants
The diversity of organisms, one of the most striking features of life on Earth, is under threat, and climate change may become a major driver of the biodiversity crisis in the decades to come. However, climate effects on species will vary across ecosystems and regions. The fate of the rich and peculiar alpine flora in ...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
10.1021/jacs.6b00070
Sizing and Discovery of Nanosized Polyoxometalate Clusters by Mass Spectrometry
Ion mobility-mass spectrometry (IM-MS) is a powerful technique for structural characterization, e. g. , sizing and conformation, particularly when combined with quantitative modeling and comparison to theoretical values. Traveling wave IM-MS (TW-IM-MS) has recently become commercially available to nonspecialist groups ...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Materials Engineering" ]
10.5194/bg-11-1065-2014
Influence of temperature and CO&lt;sub&gt;2&lt;/sub&gt; on the strontium and magnesium composition of coccolithophore calcite
Abstract. Marine calcareous sediments provide a fundamental basis for palaeoceanographic studies aiming to reconstruct past oceanic conditions and understand key biogeochemical element cycles. Calcifying unicellular phytoplankton (coccolithophores) are a major contributor to both carbon and calcium cycling by photosynt...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Physical and Analytical Chemical Sciences" ]
US 0214461 W
SYSTEM EMPLOYING CLOCK SIGNAL GENERATION AND SYNCHRONIZATION TECHNIQUE
A system (405) employing synchronous clock signals utilizes the distribution of a fast clock signal (424,425) along a forward path to clock generators for providing standard clock signals, and a recovery of such signal via a return path (445,455). The fast clock signal has a distinguishable portion, such as a periodic ...
[ "Systems and Communication Engineering", "Materials Engineering" ]
10.1038/s41588-018-0101-4
Signatures of negative selection in the genetic architecture of human complex traits
We develop a Bayesian mixed linear model that simultaneously estimates single-nucleotide polymorphism (SNP)-based heritability, polygenicity (proportion of SNPs with nonzero effects), and the relationship between SNP effect size and minor allele frequency for complex traits in conventionally unrelated individuals using...
[ "Integrative Biology: from Genes and Genomes to Systems", "Mathematics" ]
648693
No Sword Bites So Fiercly as an Evil Tongue?Gossip Wrecks Reputation, but Enhances Cooperation
Social norms in general, and norms of cooperation in particular, are the cement of all human societies. For the difficult problems of the maintenance and enforcement of social norms and of cooperation, humans have developed surprisingly complex solutions. Reputation mechanisms and gossip are certainly among the compoun...
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity", "Computer Science and Informatics" ]
10.1371/journal.pone.0095839
Marine litter distribution and density in European seas, from the shelves to deep basins
Anthropogenic litter is present in all marine habitats, from beaches to the most remote points in the oceans. On the seafloor, marine litter, particularly plastic, can accumulate in high densities with deleterious consequences for its inhabitants. Yet, because of the high cost involved with sampling the seafloor, no la...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
interreg_3430
Strategies to Reduce and Manage Food Waste in Central Europe
Wasting food is not only an ethical and economic issue but it also depletes the environment of limited natural resources. Additionally, methane emissions from improper food waste management cause high greenhouse gas emissions._x000D_ _x000D_ STREFOWA will address and improve food waste management in selected central Eu...
[ "Environmental Biology, Ecology and Evolution", "Products and Processes Engineering", "Human Mobility, Environment, and Space" ]
W2125713428
Movement of Water through Ballast and Subballast for Dual-Line Railway Track
The purpose of effective track design is to ensure that load from trains can be safely supported by subgrade soils, which are likely to be affected by water. Because it is almost impossible to prevent water from entering the ballasted track and therefore affecting the underlying layers, it is vitally important that wat...
[ "Products and Processes Engineering", "Earth System Science" ]
Q2869384
Capacity increase of Caçarola II Restaurant and Creation of local accommodation unit in Freguesia Novo – Figueira da Foz
Strengthening the capacity of the company Esteves & Martins, Lda. in the development of new services, by increasing the capacity of an existing establishment (Caçarola II Restaurant) passing the number of seats from 110 to 150 and the creation of a local accommodation unit with 9 rooms.
[ "Products and Processes Engineering" ]
W2382324001
Motion control system based on real-time ethernet
A real-time Ethernet named EtherMAC( Ethernet for Manufacture Automation Control) was developped for open computer numerical control system. A standard industrial personal computer( IPC) based master node and field programmable gate array( FPGA) based slave nodes were employed in EtherMAC,as neither dedicated network i...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
US 2015/0036602 W
360 DEGREE PRIVACY FILM
Light control films are provided that confine light transmitted therethrough to be within a 360° view region and block light outside of this view region. The light control films can provide security in all directions including right-and-left and up-and-down of the films, without compromising light transmittance compare...
[ "Materials Engineering", "Synthetic Chemistry and Materials" ]
W1614904978
Creep behavior of high-pressure die-cast Mg-4Al-4La-0.4Mn alloy under medium stresses and at intermediate temperatures
Abstract Tensile creep behavior of the high-pressure die-cast Mg-4Al-4La-0.4Mn alloy under stresses of 50–100 MPa and at 150–225 °C was thoroughly investigated. This alloy exhibits a stress exponent of approximately 6 and the activation energy Q falls within the range of 80–120 kJ/mol at 150–200 °C. From fitting result...
[ "Condensed Matter Physics", "Materials Engineering" ]
851960
Deconstructing and rebuilding the evolution of cell and tissue mechanoadaptation
Cells in our body are exceptionally robust: they constantly adapt their properties and behavior to their physical environment. Less appreciated but equally important, the extracellular matrix (ECM) around the cells also adapts to accommodate cell activity. This highly dynamic feedback between the cell and the ECM has b...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing", "Materials Engineering" ]
W1548084363
Unmixing Acoustic Sources in Real Reverberant Environments for Close-Microphone Applications*
The problem of acoustic source separation is addressed in an audio application context, especially when considering close-microphone applications and the effects of room acoustics. The framework of blind source separation (BSS) is used here to formally describe the problem, and solutions derived from this framework are...
[ "Systems and Communication Engineering", "Condensed Matter Physics" ]
US 2009/0038569 W
METHOD AND APPARATUS FOR PAPER STOCK MIXING
A method of mixing paper stock, having improved outlet consistency, includes: (a) feeding liquid and feeding paper pulp into a vessel to form a mixture; (b) providing at least one counterflow impeller that is submerged in the mixture, the counterflow impeller being capable of simultaneously inducing both upward flow an...
[ "Products and Processes Engineering", "Materials Engineering" ]
853517
Outside-in: How Bullying in Adolescence Gets Into The Mind and Under the Skin
Being bullied is a major stressor for many adolescents and it is recognized as a public health concern worldwide. Adolescents who are exposed to bullying are at increased risk for mental and physical health problems, which could even perpetuate into adulthood. Unfortunately, current understandings of how bullying can p...
[ "The Human Mind and Its Complexity", "Physiology in Health, Disease and Ageing", "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases", "The Social World and Its Interactions" ]
10.1016/j.msec.2016.02.052
Dual-modality self-heating and antibacterial polymer-coated nanoparticles for magnetic hyperthermia
Multifunctional nanoparticles for magnetic hyperthermia which simultaneously display antibacterial properties promise to decrease bacterial infections co-localized with cancers. Current methods synthesize such particles by multi-step procedures, and systematic comparisons of antibacterial properties between coatings, a...
[ "Physical and Analytical Chemical Sciences", "Immunity, Infection and Immunotherapy", "Materials Engineering" ]
851794
Toward single colloidal nanocrystal light-emitting diodes
Nanomaterials are a promising technology that includes a variety of applications ranging from electronics to medicine. Within the family of nanomaterials, colloidal semiconductor nanocrystal (NCs) are among the most investigated, thanks to their desirable optoelectronic properties. Up until now, NCs have been employed ...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Systems and Communication Engineering" ]
10.1126/scitranslmed.aax8313
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype
Blockade of epidermal growth factor receptor (EGFR) causes tumor regression in some patients with metastatic colorectal cancer (mCRC). However, residual disease reservoirs typically remain even after maximal response to therapy, leading to relapse. Using patient-derived xenografts (PDXs), we observed that mCRC cells su...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
2731040
Strengthening the sfax university expertise for diagnosis and management of epileptic encephalopathies
Epileptic encephalopathies (EE) are heterogenous epilepsy syndromes associated with severe cognitive disturbance. EE vary in their onset age, seizure types, electroencephalographic patterns and etiologies. New molecular technologies increased the genetic diagnosis rate. Inline with EU orientations and Twinning requirem...
[ "Neuroscience and Disorders of the Nervous System", "Prevention, Diagnosis and Treatment of Human Diseases" ]
FR 2018050166 W
METHOD FOR INSERTING A WIRE INTO A GROOVE OF A SEMICONDUCTOR CHIP, AND PIECE OF EQUIPMENT FOR IMPLEMENTING SUCH A METHOD
The invention relates to a method for inserting a wire (7a, 7b) into a longitudinal groove of a semiconductor chip (1) for the assembly thereof, the groove containing a pad (6a, 6b) made of a bonding material having a set melting point, the method comprising: in a positioning step, placing a longitudinal section of the...
[ "Products and Processes Engineering", "Materials Engineering" ]
W2564884355
177mLu impurity: Practical aspects of 177mLu hospital waste management
1248 Objectives In our facility we performing weekly up to two treatments with a standard dose of 7,5 GBq [Lu-177][DOTA0, Tyr3]octreotate. Due to the similar half-lives I-131 ( t1/2=8 d), Lu-177 ( t1/2= 6,7 d) and Y-90 (t1/2=2,6 d) were released in one tank. Depending on the production route there could be impurities o...
[ "Physical and Analytical Chemical Sciences", "Products and Processes Engineering" ]
10.1039/C8NR01365A
A Highly Thermally Stable Sub 20 Nm Magnetic Random Access Memory Based On Perpendicular Shape Anisotropy
A new approach to increase the downsize scalability of perpendicular STT-MRAM is presented. It consists of significantly increasing the thickness of the storage layer in out-of-plane magnetized tunnel junctions (pMTJ) as compared to conventional pMTJ in order to induce a perpendicular shape anisotropy (PSA) in this lay...
[ "Condensed Matter Physics", "Materials Engineering" ]
W438326429
Capital markets integration: A sociotechnical study of the development of a cross-border securities settlement system
Digital information and communications technologies (ICTs) are transforming capital markets. The integration of capital markets is seen as one such area of transformation. The research presented in this article studies one integration initiative that took shape around the proposed combination of a number of key Europea...
[ "Individuals, Markets and Organisations", "Computer Science and Informatics", "The Social World and Its Interactions" ]
W1981103082
Radiosensitivity, liquid-holding recovery and relative biological effectiveness of densely-ionizing radiation after repeated irradiation of yeast cells
Experimental results described earlier showed significantly larger relative biological effectiveness (RBE) values for wild-type diploid cells in comparison with radiosensitive mutants. This aspect was further studied in this paper. Diploid yeast cells were irradiated with gamma rays from (60)Co and alpha particles from...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Fundamental Constituents of Matter", "Cell Biology, Development, Stem Cells and Regeneration" ]
W4283738986
Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalization in Health Care Workers
This study examines the risk of long COVID following mRNA vaccination, compared with no vaccination, in health care workers in Italy who had COVID-19 infection.
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
802093
EXPLORING NONLINEAR DYNAMICS IN GRAPHENE NANOMECHANICAL SYSTEMS
Micro and nanomechanical systems are being adopted in billions of products, that address a wide range of sensor and actuator applications in modern technology. The advent of graphene, and the ability to fabricate single atom thick membranes, promises further device downscaling, enabling ultimate sensing capabilities th...
[ "Condensed Matter Physics", "Materials Engineering", "Synthetic Chemistry and Materials" ]
W2279970817
Study on the thermodynamics of the gadolinium-hydrogen binary system (H/Gd = 0.0–2.0) and implications to metallic gadolinium purification
Abstract The thermodynamics of the gadolinium-hydrogen (Gd–H) binary system (H/Gd = 0.0–2.0) between 650 and 900 °C is studied by pressure composition isotherm measurement. Significant H dissolution in Gd is observed, up to H/Gd = 0.34 at 650 °C and 0.55 at 900 °C. The metal-rich phase boundary of nonstoichiometric gad...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1039/C7AN00544J
Thiol Ene Micropillar Array Electrospray Ionization Platform For Zeptomole Level Bioanalysis
A micropillar array electrospray ionization (μPESI) platform fabricated from thiol–enes with 56 individual polyethylene glycol coated μPESI chips for bioanalytical mass spectrometry is introduced. Bioanalysis capability is shown by measurement of a protein, a protein digest and a cell lysate sample. The thiol–ene polye...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1039/C3NR03335J
Assessing The Relevance Of Building Block Crystallinity For Tuning The Stiffness Of Gold Nanocrystal Superlattices
We study the influence of the size and nanocrystallinity of dodecanethiol-coated gold nanocrystals (NCs) on the stiffness of 3D self-assembled NC superlattices (called supracrystals). Using single domain and polycrystalline NCs as building blocks for supracrystals, it is shown that the stiffness of supracrystals can be...
[ "Condensed Matter Physics", "Materials Engineering" ]
890359
The next 100 optimizing compilers
Ideally, advances in hardware design would directly translate to performance or energy improvements in software. In reality, this involves a manual process of tuning a sophisticated production compiler or hardware-specific rewriting of code. This process is challenging even for the few experts who possess the required ...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
TW 97117024 A
System for 3D image projections and viewing
Shaped glasses have curved surface lenses and spectrally complementary filters disposed on the curved surface lenses configured to compensate for wavelength shifts occurring due to viewing angles and other sources. The spectrally complementary filters include guard bands to prevent crosstalk between spectrally compleme...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
EP 2020067289 W
FEED ADDITIVE
The present invention pertains to a feed additive for monogastric animal feed comprising at least two TRP modulators capable of improving calcium uptake in the intestine of a monogastric animal, and a controlled release agent, wherein the feed additive comprises carvacrol and vanillin.
[ "Products and Processes Engineering", "Biotechnology and Biosystems Engineering" ]
W2732504061
FDM simulation of earthquakes off western Kyushu, Japan, using a land–ocean unified 3D structure model
Seismic activity occurred off western Kyushu, Japan, at the northern end of the Okinawa Trough on May 6, 2016 (14:11 JST), 22 days after the onset of the 2016 Kumamoto earthquake sequence. The area is adjacent to the Beppu–Shimabara graben where the 2016 Kumamoto earthquake sequence occurred. In the area off western Ky...
[ "Earth System Science", "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1016/j.celrep.2016.10.021
SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis
Actin plays a critical role during the early stages of pathogenic microbe internalization by immune cells. In this study, we identified a key mechanism of actin filament tethering and stabilization to the surface of phagosomes in human dendritic cells. We found that the actin-binding protein SWAP70 is specifically recr...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1109/ICCV.2019.00272
Howto100M Learning A Text Video Embedding By Watching Hundred Million Narrated Video Clips
Learning text-video embeddings usually requires a dataset of video clips with manually provided captions. However, such datasets are expensive and time consuming to create and therefore difficult to obtain on a large scale. In this work, we propose instead to learn such embeddings from video data with readily available...
[ "Computer Science and Informatics" ]
10.1016/j.neuron.2011.04.022
Nuclear Calcium-VEGFD Signaling Controls Maintenance of Dendrite Arborization Necessary for Memory Formation
The role of neuronal dendrites is to receive and process synaptic inputs. The geometry of the dendritic arbor can undergo neuronal activity-dependent changes that may impact the cognitive abilities of the organism. Here we show that vascular endothelial growth factor D (VEGFD), commonly known as an angiogenic mitogen, ...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1126/science.1259657
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra Leone, and Nigeria. We sequenced 99 Ebola virus genomes from 78 patients in Sierra Leone to ∼2000× coverage. We observed a rapid accumulation of interhost and intrahost genetic variation, allowing us to characterize patterns of vi...
[ "Integrative Biology: from Genes and Genomes to Systems", "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1145/2678025.2716265
Modelling User Affect And Sentiment In Intelligent User Interfaces A Tutorial Overview
The computer-based automatic analysis of human sentiment, and affect are broadly expected to play a major role that will likely make 'that difference' in future Intelligent User Interfaces, as they bear the promise to lend interactive systems emotional intelligence. Such comprise intelligent digital games, e. g. , for ...
[ "Computer Science and Informatics", "The Human Mind and Its Complexity" ]
SE 9200241 W
GASSPRING WHICH AFTER COMPRESSION HAS A TIME DELAYED RETURN TO ITS ORIGINAL LENGTH
The invention consists on the one hand of a cylinder (2) closed at its ends by means of end walls (4, 5) and on the other hand of an enclosed space (10). With a piston (3) capable of axial displacement, the cylinder (2) is divided into two sub-spaces (6, 7). The space (10) communicates with the aforementioned first sub...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
W4226345140
Literatura y diversidad en la formación docente: el aula de Magisterio como espacio de reflexión
The presence of diversity in our schools is undoubtedly one of the great educational challenges of our time: therefore, the training received by future teachers also must be in the focus of our concern. In this paper we intend to approach the ideas and beliefs of Teaching students about children's literature as a tool ...
[ "Texts and Concepts", "The Social World and Its Interactions" ]
10.1103/PhysRevB.93.205410
Nanometer-scale monitoring of quantum-confined Stark effect and emission efficiency droop in multiple GaN/AlN quantum disks in nanowires
We report on a detailed study of the intensity dependent optical properties of individual GaN/AlN quantum disks (QDisks) embedded into GaN nanowires (NW). The structural and optical properties of the QDisks were probed by high spatial resolution cathodoluminescence (CL) in a scanning transmission electron microscope (S...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
10.1063/1.5086091
Broadband Lumped Element Josephson Parametric Amplifier With Single Step Lithography
We present a lumped-element Josephson parametric amplifier (JPA) utilizing a straightforward fabrication process involving a single electron beam lithography step followed by double-angle evaporation of aluminum and in-situ oxidation. The Josephson junctions forming the SQUID are fabricated using bridgeless shadow evap...
[ "Condensed Matter Physics", "Systems and Communication Engineering" ]
10.1093/bioinformatics/bts496
Shortran: A pipeline for small RNA-seq data analysis
High-throughput sequencing currently generates a wealth of small RNA (sRNA) data, making data mining a topical issue. Processing of these large data sets is inherently multidimensional as length, abundance, sequence composition, and genomic location all hold clues to sRNA function. Analysis can be challenging because t...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
694819
EXPERIMENTAL CONSTRAINTS ON THE ISOTOPE SIGNATURES OF THE EARLY SOLAR SYSTEM
This project aims at simulating the processes that took place in the early Solar System to determine how these processes shaped the chemical and isotope compositions of solids that accreted to ultimately form terrestrial planets. Planetary materials exhibit mass dependent and mass independent isotope signatures and the...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics", "Universe Sciences" ]
10.1038/nature16325
Regenerative biology: Innate immunity repairs gut lining
It emerges that innate immune cells called group 3 innate lymphoid cells signal directly to intestinal stem cells to promote the replacement of damaged epithelial cells lining the gut.
[ "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1142/S0129167X10006215
Second Order Quasilinear Pdes And Conformal Structures In Projective Space
We investigate second-order quasilinear equations of the form fijuxixj = 0, where u is a function of n independent variables x1, …, xn, and the coefficients fij depend on the first-order derivatives p1 = ux1, …, pn = uxn only. We demonstrate that the natural equivalence group of the problem is isomorphic to SL(n + 1, R...
[ "Mathematics" ]
10.1002/adma.201900488
Immunogold FIB-SEM: Combining Volumetric Ultrastructure Visualization with 3D Biomolecular Analysis to Dissect Cell–Environment Interactions
Volumetric imaging techniques capable of correlating structural and functional information with nanoscale resolution are necessary to broaden the insight into cellular processes within complex biological systems. The recent emergence of focused ion beam scanning electron microscopy (FIB-SEM) has provided unparalleled i...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
10.1109/TMAG.2016.2590384
Magnetomechanical Model for Hysteresis in Electrical Steel Sheet
A coupled magnetomechanical model for hysteresis in an electrical steel sheet is presented. The foundation of the model developed is the classical Sablik-Jiles-Atherton (SJA) model. A comprehensive model for the stress-dependent magnetostriction is also proposed and implemented in the SJA model. Improvements in the SJA...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1038/ncomms5731
An engineered pathway for the biosynthesis of renewable propane
The deployment of next-generation renewable biofuels can be enhanced by improving their compatibility with the current infrastructure for transportation, storage and utilization. Propane, the bulk component of liquid petroleum gas, is an appealing target as it already has a global market. In addition, it is a gas under...
[ "Synthetic Chemistry and Materials", "Biotechnology and Biosystems Engineering" ]
10.1353/ajm.2018.0019
Sampling of real multivariate polynomials and pluripotential theory
We consider the problem of stable sampling of multivariate real polynomials of large degree in a general framework where the polynomials are defined on an affine real algebraic variety M, equipped with a weighted measure. In particular, this framework contains the well-known setting of trigonometric polynomials (when M...
[ "Mathematics" ]
W2587603968
Informačný systém pre hodnotenie zamestnancov.
The undergraduate thesis deals with the development process of an information system from the first analysis of system requirements to the design and realisation and up to the final implementation. The first chapter addresses the explanation of basic terms. The second chapter addresses the analysis of the requirements ...
[ "Computer Science and Informatics" ]
175247
Automatic rail safety solution
By 2025 1800km of rail lines will be automated worldwide. With the increase in automatic train operation comes the need to create an innovative platform and track protection system to ensure the security of passengers while maintaining increased efficiency in public transport. According to the European Railway Agency i...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1134/S0021364017020011
Dark Matter From Dark Energy In Q Theory
A constant (spacetime-independent) $q$-field may play a crucial role for the cancellation of Planck-scale contributions to the gravitating vacuum energy density. We now show that a small spacetime-dependent perturbation of the equilibrium $q$-field behaves gravitationally as a pressureless perfect fluid. This makes the...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
10.1098/rsif.2016.0918
A mathematical model of tumour angiogenesis: Growth, regression and regrowth
Cancerous tumours have the ability to recruit new blood vessels through a process called angiogenesis. By stimulating vascular growth, tumours get connected to the circulatory system, receive nutrients and open a way to colonize distant organs. Tumour-induced vascular networks become unstable in the absence of tumour a...
[ "Mathematics", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
10.1128/AEM.02250-15
Anodes Stimulate Anaerobic Toluene Degradation Via Sulfur Cycling In Marine Sediments
Hydrocarbons released during oil spills are persistent in marine sediments due to the absence of suitable electron acceptors below the oxic zone. Here, we investigated an alternative bioremediation strategy to remove toluene, a model monoaromatic hydrocarbon, using a bioanode. Bioelectrochemical reactors were inoculate...
[ "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering", "Physical and Analytical Chemical Sciences", "Earth System Science" ]
10.1177/1745691614526414
Banishing The Control Homunculi In Studies Of Action Control And Behavior Change
For centuries, human self-control has fascinated scientists and nonscientists alike. Current theories often attribute it to an executive control system. But even though executive control receives a great deal of attention across disciplines, most aspects of it are still poorly understood. Many theories rely on an ill-d...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1111/j.1365-2745.2012.01990.x
Driving factors of forest growth: A reply to Ferry et al. (2012)
1. In a recent paper, we analysed the effects of climate, soil and logging disturbance on tree and forest growth (Toledo et al. 2011a). We took advantage of one of the largest data sets in the Neotropics, consisting of 165 1-ha plots and over 62000 trees distributed over an area of c. 160000km 2, across large environm...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
10.7554/elife.47528
Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells
Planar supported lipid bilayers (PSLB) presenting T cell receptor (TCR) ligands and ICAM-1 induce budding of extracellular microvesicles enriched in functional TCR, defined here as synaptic ectosomes (SE), from helper T cells. SE bind peptide-MHC directly exporting TCR into the synaptic cleft, but incorporation of othe...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1039/C2CS35023H
Diversity Oriented Synthesis Producing Chemical Tools For Dissecting Biology
Small molecule modulators of biological function can be discovered by the screening of compound libraries. However, it became apparent that some human disease related targets could not be addressed by the libraries commonly used which typically are comprised of large numbers of structurally similar compounds. The last ...
[ "Synthetic Chemistry and Materials", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1080/02723638.2016.1139879
Anticipatory Logics Of The Smart City S Global Imaginary
The smart city encompasses a broad range of technological innovations which might be applied to any city for a wide variety of reasons. In this article, I make a distinction between local efforts t . . .
[ "Computer Science and Informatics", "The Social World and Its Interactions" ]
10.1089/ars.2012.4671
The microglial α7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2
Aims: We asked whether the neuroprotective effect of cholinergic microglial stimulation during an ischemic event acts via a mechanism involving the activation of nuclear factor erythroid-2-related factor 2 (Nrf2) and/or the expression of its target cytoprotective gene, heme oxygenase-1 (HO-1). Specifically, the protect...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy" ]
10.1091/mbc.E19-02-0082
Reciprocal regulation of actomyosin organization and contractility in nonmuscle cells by tropomyosins and alpha-actinins
Contractile arrays of actin and myosin II filaments drive many essential processes in nonmuscle cells, including migration and adhesion. Sequential organization of actin and myosin along one dimension is followed by expansion into a two-dimensional network of parallel actomyosin fibers, in which myosin filaments are al...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1111/jmg.12213
Effect of grain-scale pressure variations on garnet growth: a numerical approach
Grain-scale pressure variations have recently been investigated due to its significant effect on the observed microstructures and chemical redistribution in metamorphic rocks. In this study, the impact of grain-scale pressure variation on a growing garnet grain is investigated. We model prograde garnet growth at fluid-...
[ "Earth System Science", "Physical and Analytical Chemical Sciences" ]
10.1007/978-3-319-15976-8_1
Tackling Exascale Software Challenges In Molecular Dynamics Simulations With Gromacs
GROMACS is a widely used package for biomolecular simulation, and over the last two decades it has evolved from small-scale efficiency to advanced heterogeneous acceleration and multi-level parallelism targeting some of the largest supercomputers in the world. Here, we describe some of the ways we have been able to rea...
[ "Computer Science and Informatics", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1104/pp.16.00213
Molecular characterization of arabidopsis GAL4/UAS enhancer trap lines identifies novel cell-type-specific promoters
Cell-type-specific gene expression is essential to distinguish between the numerous cell types of multicellular organism. Therefore, cell-type-specific gene expression is tightly regulated and for most genes RNA transcription is the central point of control. Thus, transcriptional reporters are broadly used markers for ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1002/cphc.201402300
A Multifrequency Virtual Spectrometer for Complex Bio-Organic Systems: Vibronic and Environmental Effects on the UV/Vis Spectrum of Chlorophyll a
The subtle interplay of several different effects means that the interpretation and analysis of experimental spectra in terms of structural and dynamic characteristics is a challenging task. In this context, theoretical studies can be helpful, and as such, computational spectroscopy is rapidly evolving from a highly sp...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1016/j.quaint.2018.03.043
Magnetostratigraphic and chronostratigraphic constraints on the Marathousa 1 Lower Palaeolithic site and the Middle Pleistocene deposits of the Megalopolis basin, Greece
We investigated the magnetostratigraphy of the Megalopolis basin in central Peloponnese, Greece, which encompasses a record of Pleistocene lacustrine and lignite-bearing sedimentation, where lithic tools stratigraphically associated with remnants of an almost complete skeleton of Palaeoloxodon antiquus were recently fo...
[ "The Study of the Human Past", "Earth System Science" ]
W2389805888
The Applications Particulate Li DAR in the Stereo-Monitoring for the Complex Atmospheric Pollution
To analyze the three different mechanisms for the haze formation respectively caused by local pollutants,dust sunk,and the superposition with local pollution diffusion and exogenous pollution input,we applied particulate Li DAR to detect the spatial and temporal characteristics of suspended particulate matter in three ...
[ "Earth System Science", "Systems and Communication Engineering" ]
EP 9402347 W
AN ETHANOL FUEL AND THE USE OF AN IGNITION IMPROVER
The ignition of an aqueous ethanol fuel is essentially improved by using a water soluble adduct of a polyol having 3-10 hydroxyl groups and ethylene oxide and/or propylene oxide, the molecular weight of the adduct being 350-10,000. The fuel is in the form of a solution and contains 70-96 % by weight of ethanol, 2-10 % ...
[ "Physical and Analytical Chemical Sciences", "Products and Processes Engineering" ]
10.1002/ece3.831
Deflective and intimidating eyespots: A comparative study of eyespot size and position in Junonia butterflies
Eyespots are conspicuous circular features found on the wings of several lepidopteran insects. Two prominent hypotheses have been put forth explaining their function in an antipredatory role. The deflection hypothesis posits that eyespots enhance survival in direct physical encounters with predators by deflecting attac...
[ "Environmental Biology, Ecology and Evolution" ]
W4284671959
Colaboração brasileira com autores da Austrália, Canadá, Estados Unidos e Reino Unido e o desempenho das Universidades no Ranking ARWUGRAS
Objetivo: identificar as disciplinas e universidades brasileiras que se beneficiam da colaboração científica com Austrália, Canadá, Estados Unidos e Reino Unido, visualizado a partir do desempenho no Global Ranking of Academic Subjects (ARWUGRAS). Método: estudo exploratório que identificou os artigos brasileiros index...
[ "Individuals, Markets and Organisations", "The Social World and Its Interactions" ]
10.1002/2016JG003615
Erosion Of Organic Carbon From The Andes And Its Effects On Ecosystem Carbon Dioxide Balance
Productive forests of the Andes are subject to high erosion rates that supply to the Amazon River sediment and carbon from both recently photosynthesized biomass and geological sources. Despite this recognition, the source and discharge of particulate organic carbon (POC) in Andean rivers remains poorly constrained. We...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Physical and Analytical Chemical Sciences" ]
10.1109/CDC.2014.7039771
Towards Time Optimal Race Car Driving Using Nonlinear Mpc In Real Time
This paper addresses the real-time control of autonomous vehicles under a minimum traveling time objective. Control inputs for the vehicle are computed from a nonlinear model predictive control (MPC) scheme. The time-optimal objective is reformulated such that it can be tackled by existing efficient algorithms for real...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
W2091480326
Driving photochemistry by clustering: The ICl-Xe case
We present slice imaging data demonstrating the influence of clustering on the photodissociation dynamics of a diatomic molecule: iodine monochloride (ICl) was dissociated at 235 nm in He and Xe seed gasses, probing both Cl and I photofragment energy and angular distributions. We observe that the kinetic energy release...
[ "Physical and Analytical Chemical Sciences", "Fundamental Constituents of Matter" ]
10.1093/jfr/fjx005
Culprits or Bystanders? Offshore Jurisdictions and the Global Financial Crisis
ABSTRACT Questions have been raised regarding the role of low-tax offshore jurisdictions in the global financial crisis, based largely on evidence that many problematic asset-backed securities were issued from or listed in the Cayman Islands, Jersey, Ireland, and other ‘offshore’ sites. However, there has not been a sy...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems" ]
10.1257/aer.20150774
This Mine is Mine! How Minerals Fuel Conflicts in Africa
We combine georeferenced data on mining extraction of 14 minerals with information on conflict events at spatial resolution of 0. 5 o × 0. 5 o for all of Africa between 1997 and 2010. Exploiting exogenous variations in world prices, we find a positive impact of mining on conflict at the local level. Quantitatively, our...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems", "The Social World and Its Interactions" ]
10.1007/978-3-319-00885-1_6
Multi Level Monte Carlo Finite Volume Methods For Uncertainty Quantification In Nonlinear Systems Of Balance Laws
A mathematical formulation of conservation and of balance laws with random input data, specifically with random initial conditions, random source terms and random flux functions, is reviewed. The concept of random entropy solution is specified. For scalar conservation laws in multi-dimensions, recent results on the exi...
[ "Mathematics", "Computer Science and Informatics" ]
W2769158280
Fishing fleet capacity and profitability
Abstract The individual transferable quotas (ITQ) system is a popular fisheries management system applied in many countries. Here, vessels are scrapped or sold out of the fishery, and their quotas are transferred to the remaining vessels, resulting in lower number of active vessels. This consequently reduces the overca...
[ "Individuals, Markets and Organisations", "Environmental Biology, Ecology and Evolution" ]
223624
Demonstration of the next generation wave energy device – powermodule
Wello has developed and patented a concept which is able to convert the movement of waves into electric energy without any hydraulic joints and gears. The idea of Wello’s Power Module innovation is to combine vessel stabilization, damping and power production into one electro-mechanical device. This is achieved by inst...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1002/macp.201600502
Energy Level Tuning of Poly(phenylene-alt-dithienobenzothiadiazole)s for Low Photon Energy Loss Solar Cells
Six poly(phenylene-alt-dithienobenzothiadiazole)-based polymers have been synthesized for application in polymer–fullerene solar cells. Hydrogen, fluorine, or nitrile substitution on benzo­thiadiazole and alkoxy or ester substitution on the phenylene moiety are investigated to reduce the energy loss per converted photo...
[ "Condensed Matter Physics", "Synthetic Chemistry and Materials", "Materials Engineering" ]
W2037385914
Precious metal enrichment in the Platreef, Bushveld Complex, South Africa: evidence from homogenized magmatic sulfide melt inclusions
Magmatic sulfide deposits are the most significant source of platinum-group elements (PGE) in the world. Key to understanding their genesis is determining the processes and timing of sulfide saturation, metal enrichment and crustal contamination. In this study, we have identified droplets of magmatic sulfide from the P...
[ "Earth System Science", "Physical and Analytical Chemical Sciences" ]
10.1128/AEM.01066-14
Ether- and ester-bound iso-diabolic acid and other lipids in members of Acidobacteria subdivision 4
Recently, iso-diabolic acid (13,16-dimethyl octacosanedioic acid) has been identified as a major membrane-spanning lipid of subdivisions 1 and 3 of the Acidobacteria, a highly diverse phylum within the Bacteria. This finding pointed to the Acidobacteria as a potential source for the bacterial glycerol dialkyl glycerol ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Earth System Science" ]