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Q3844224
Improving the processes of management and organizational innovations in Borola Ltd.
Our overall concept is related to supporting a healthy lifestyle and creating a health culture in modern people. Since our creation in 1996 we have developed our ideas, and for 20 years we managed to become the only company in Bulgaria, which besides a manufacturer of food supplements and cosmetics, has a comprehensive...
[ "Products and Processes Engineering", "Individuals, Markets and Organisations" ]
W2902821133
Special Issue on Globalization, Cosmopolitanism, and Migration: Ethics of Inclusion and Exclusion
The contributors to this issue offer applied critical and normative perspectives on central, yet overlooked, ethical aspects of migration management with a certain cosmopolitan lance in some capacity. However, cosmopolitanism might mean different things for transnational migration. It can refer to “political cosmopolit...
[ "Institutions, Governance and Legal Systems", "The Social World and Its Interactions", "Human Mobility, Environment, and Space" ]
10.1083/jcb.200903131
Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy
Mammalian target of rapamycin (mTOR) is a key regulator of cell growth that associates with raptor and rictor to form the mTOR complex 1 (mTORC1) and mTORC2, respectively. Raptor is required for oxidative muscle integrity, whereas rictor is dispensable. In this study, we show that muscle-specific inactivation of mTOR l...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1007/s00216-011-5556-4
Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS)
Here we present an ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method for extracellular measurements of known and unexpected metabolites in parallel. The method was developed by testing 86 metabolites, including amino acids, organic acids, sugars, purines, pyrimidines, vitamins, and nucleosides,...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2381892345
The Design of Vegetable Greenhouse Temperature and Humidity Monitoring System Based on ARM11 Processor
According to the application requirements of vegetable greenhouse temperature and humidity monitoring,it needs to de-sign a greenhouse temperature and humidity monitoring system based on ARM11 processor.This paper firstly analyzes the selection of tem-perature and humidity sensor and ARM processor and function in detai...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1016/j.jmb.2016.10.012
The Multiple Facets of PRC2 Alterations in Cancers
Genome sequencing of large cohorts of tumors has revealed that mutations in genes encoding chromatin regulators are frequent in cancer. However, the precise contribution of these mutations to tumor development often remains elusive. Here, we review the current knowledge concerning the alterations of the Polycomb machin...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems", "Physiology in Health, Disease and Ageing" ]
10.1016/j.culher.2017.09.008
What is a nautical chart, really? Uncovering the geometry of early modern nautical charts
During the sixteenth century and beyond, nautical charts were the single most important source of geographical information for the image of the world that was depicted in European maps and atlases. However, little was known until very recently about the geometry of these remarkable artefacts. Making use of results obta...
[ "The Study of the Human Past", "Mathematics" ]
10.1074/jbc.M114.596585
Aberrant assembly complexes of the reaction center light-harvesting 1 PufX (RC-LH1-PufX) core complex of rhodobacter sphaeroides imaged by atomic force microscopy
In the purple phototrophic bacterium Rhodobacter sphaeroides, manyproteincomplexescongregate within themembrane to form operational photosynthetic units consisting of arrays of light-harvesting LH2 complexes and monomeric and dimeric reaction center (RC)-light-harvesting 1 (LH1)-PufX "core" complexes. Each half of a di...
[ "Condensed Matter Physics", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W1996673298
Hydrogen generated from hydrolysis of ammonia borane using cobalt and ruthenium based catalysts
Abstract Ammonia borane (NH 3 BH 3 , AB), one kind of promising hydrogen storage materials, is hydrolyzed to produce hydrogen in presence of HCl, Co/IR-120 and Ru/IR-120 catalysts. The kinetics analysis of the AB hydrolysis shows that hydrogen production is of the first-order reaction in regard to both concentrations o...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Products and Processes Engineering" ]
10.1103/PhysRevB.94.165141
Capturing nonlocal interaction effects in the Hubbard model: Optimal mappings and limits of applicability
We investigate the Peierls-Feynman-Bogoliubov variational principle to map Hubbard models with nonlocal interactions to effective models with only local interactions. We study the renormalization of the local interaction induced by nearest-neighbor interaction and assess the quality of the effective Hubbard models in r...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
10.1186/s13059-017-1278-z
Large scale genomic reorganization of topological domains at the HoxD locus
Background: The transcriptional activation of HoxD genes during mammalian limb development involves dynamic interactions with two topologically associating domains (TADs) flanking the HoxD cluster. In particular, the activation of the most posterior HoxD genes in developing digits is controlled by regulatory elements l...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
interreg_609
Central Europe Eco-Tourism: tools for nature protection
The last State of Environment Report (SOER 2015, by European Environmental Agency) states that the most effective goal related to nature conservation is to foster ecosystems resilience and in this vision human activities are the main driving forces. Within the Protected Areas (PAs) involved in CEETO tourism, of all the...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Human Mobility, Environment, and Space" ]
10.1038/NCHEM.1343
Ultrafast Dynamics In The Power Stroke Of A Molecular Rotary Motor
Light-driven molecular motors convert light into mechanical energy through excited-state reactions. Unidirectional rotary molecular motors based on chiral overcrowded alkenes operate through consecutive photochemical and thermal steps. The thermal (helix inverting) step has been optimized successfully through variation...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.4324/9780203804803
The Conceptual Politics Of Democracy Promotion
European Research Council, Political Economies of Democratisation, ERC grant number 202 596.
[ "Institutions, Governance and Legal Systems" ]
10.1021/acsnano.8b06464
All-2D Material Inkjet-Printed Capacitors: Toward Fully Printed Integrated Circuits
A well-defined insulating layer is of primary importance in the fabrication of passive (e. g. , capacitors) and active (e. g. , transistors) components in integrated circuits. One of the most widely known two-dimensional (2D) dielectric materials is hexagonal boron nitride (hBN). Solution-based techniques are cost-effe...
[ "Condensed Matter Physics", "Systems and Communication Engineering", "Materials Engineering" ]
W2041544866
Electrochemical and electrogravimetric behaviors of conducting polymer. Theoretical aspects and application to co-polymer films based on juglone
Redox mechanisms of conducting polymers are not yet fully understood. Attractive analytical tools and pertinent models are necessary to achieve this goal. In this paper, numerical simulations based on a theory dealing with ions transfer through electroactive film/electrolyte interface was developed to predict the behav...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Condensed Matter Physics" ]
10.1088/1361-6463/aa935d
Comprehensive analyses of core-shell InGaN/GaN single nanowire photodiodes
Single nitride nanowire core/shell n-p photodetectors are fabricated and analyzed. Nanowires consisting of an n-doped GaN stem, a radial InGaN/GaN multiple quantum well system and a p-doped GaN external shell were grown by catalyst-free metal-organic vapour phase epitaxy on sapphire substrates. Single nanowires were di...
[ "Condensed Matter Physics", "Systems and Communication Engineering" ]
10.1039/C8OB02243G
Self Assembled Micro Fibres By Oxime Connection Of Linear Peptide Amphiphiles
Linear peptide amphiphiles are excellent biocompatible scaffolds for the hierarchical self-assembly of one-dimensional nano-structures in aqueous media. However, their structural exploration and screening of self-assembling properties are often limited by time-consuming synthesis and purification steps. We here describ...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
US 0308896 W
AUTOMATIC SEQUENTIAL TUNING OF NARROWBAND RECEIVERS OF A WIRELESS LOCATION SYSTEM FOR VOICE/TRAFFIC CHANNEL TRACKING
In a wireless location system, narrowband receivers are used in a mode, known as automatic sequential tuning, in which the receivers are tuned sequentially and in unison to a plurality of predefined RF channels. Signal transmissions in these channels are digitally recorded and used in location processing. A location re...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1002/cbic.201900047
Biocatalytic Protein-Based Materials for Integration into Energy Devices
There is a current need to fabricate new biobased functional materials. Bottom-up approaches to assemble simple molecular units have shown promise for biomaterial fabrication due to their tunability and versatility for the incorporation of functionalities. Herein, the fabrication of catalytic protein thin films by the ...
[ "Materials Engineering", "Biotechnology and Biosystems Engineering", "Synthetic Chemistry and Materials", "Products and Processes Engineering" ]
10.1083/jcb.201411093
VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity
Cytotoxic T lymphocytes (CTLs) eliminate infected and neoplastic cells through directed release of cytotoxic granule contents. Although multiple SNARE proteins have been implicated in cytotoxic granule exocytosis, the role of vesicular SNARE proteins, i. e. , vesicle-associated membrane proteins (VAMPs), remains enigma...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1146/annurev-phyto-080615-095959
A Multiscale Approach to Plant Disease Using the Metacommunity Concept
Plant disease arises from the interaction of processes occurring at multiple spatial and temporal scales. With new tools such as next-generation sequencing, we are learning about the diversity of microbes circulating within and among plant populations and often coinhabiting host individuals. The proliferation of pathog...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1364/OL.42.004307
Single Shot Ultrafast Laser Processing Of High Aspect Ratio Nanochannels Using Elliptical Bessel Beams
Ultrafast lasers have revolutionized material processing, opening a wealth of new applications in many areas of science. A recent technology that allows the cleaving of transparent materials via non-ablative processes is based on focusing and translating a high-intensity laser beam within a material to induce a well-de...
[ "Condensed Matter Physics", "Materials Engineering", "Physical and Analytical Chemical Sciences" ]
10.1038/cdd.2013.60
Contribution of humoral immune responses to the antitumor effects mediated by anthracyclines
Immunogenic cell death induced by cytotoxic compounds contributes to the success of selected chemotherapies by eliciting a protective anticancer immune response, which is mediated by CD4 + and CD8 + T cells producing interferon-γ. In many instances, cancer progression is associated with high titers of tumor-specific an...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1109/EMBC.2015.7320050
Hardware In The Loop Simulation And Energy Optimization Of Cardiac Pacemakers
Implantable cardiac pacemakers are medical devices that can monitor and correct abnormal heart rhythms. To provide the necessary safety assurance for pacemaker software, both testing and verification of the code, as well as testing the entire pacemaker hardware in the loop, is necessary. In this paper, we present a har...
[ "Systems and Communication Engineering", "Computer Science and Informatics", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W1943671851
Stability of social behavior in captive American Flamingos (<i>Phoenicopterus ruber</i>): A quantitative case study
Over a three-year period a captive American flamingo (Phoenicopterus ruber) group showed recurring seasonal changes in the pattern of agonistic behavior. In spite of seasonal changes in the rates of agonistic behavior, dominance relations were generally stable across seasons. Males had significantly higher dominance st...
[ "Environmental Biology, Ecology and Evolution", "The Social World and Its Interactions" ]
10.1145/3299869.3324961
A Layered Aggregate Engine For Analytics Workloads
This paper introduces LMFAO (Layered Multiple Functional Aggregate Optimization), an in-memory optimization and execution engine for batches of aggregates over the input database. The primary motivation for this work stems from the observation that for a variety of analytics over databases, their data-intensive tasks c...
[ "Computer Science and Informatics" ]
10.1145/2732527
Lod Generation For Urban Scenes
We introduce a novel approach that reconstructs 3D urban scenes in the form of levels of detail (LODs). Starting from raw datasets such as surface meshes generated by multiview stereo systems, our algorithm proceeds in three main steps: classification, abstraction, and reconstruction. From geometric attributes and a se...
[ "Computer Science and Informatics", "Products and Processes Engineering" ]
324146
Pacific Presences: Oceanic Art and European Museums
This project investigates major ethnographic collections that entered European museums during the nineteenth and early twentieth centuries, and have remained largely unstudied since. Focussing on materials from the Pacific that are now in museums in Russia, Germany, the Netherlands, France and the United Kingdom, it wi...
[ "Studies of Cultures and Arts", "The Study of the Human Past" ]
10.1038/nrneurol.2015.123
Cell-based therapies for Parkinson disease-past insights and future potential
Parkinson disease (PD) is characterized by loss of the A9 nigral neurons that provide dopaminergic innervation to the striatum. This discovery led to the successful instigation of dopaminergic drug treatments in the 1960s, although these drugs were soon recognized to lose some of their efficacy and generate their own a...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1016/j.bbapap.2017.02.007
The papain-like cysteine proteinases NbCysP6 and NbCysP7 are highly processive enzymes with substrate specificities complementary to Nicotiana benthamiana cathepsin B
The tobacco-related plant Nicotiana benthamiana is gaining interest as a versatile host for the production of monoclonal antibodies and other protein therapeutics. However, the susceptibility of plant-derived recombinant proteins to endogenous proteolytic enzymes limits their use as biopharmaceuticals. We have now iden...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering" ]
SE 9901101 W
A SWITCHING DEVICE
A device for protecting, in a multiphase electric power plant for alternating voltage, one or more objects from over-currents and/or over-voltages, said objects being connected to an electric power network or another equipment comprised in the electric power plant, said device comprising an arrangement for reducing ove...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1109/IROS.2015.7353855
Learning Predictive State Representations For Planning
Predictive State Representations (PSRs) allow modeling of dynamical systems directly in observables and without relying on latent variable representations. A problem that arises from learning PSRs is that it is often hard to attribute semantic meaning to the learned representation. This makes generalization and plannin...
[ "Computer Science and Informatics" ]
W1946042141
Research on yield estimation of rice based on remote sensing using moderate-resolution imaging spectroradiometer(MODIS) data: a case study of Jiangsu Province, China.
Based on the unique characteristic of high soil moisture in the flooding and transplanting period of rice, rice pixels in Jiangsu Province, China were extracted by vegetation index algorithm. The unique characteristic could be reflected by relationship between different vegetation indexes derived from MODIS09 data. The...
[ "Earth System Science", "Computer Science and Informatics" ]
GB 1804349 A
Improvements in thread carrier driving mechanism for straight bar knitting machines
673,979. Knitting. COLTON, L. H. (Thiede, W.). July 8, 1949, No. 18043/49. Class 74 (ii). A straight-bar knitting-machine has a positive thread carrier drive, providing a substantially constant lead of the thread carrier or carriers in front of the slurcock, in which a coupling device for engaging and disengaging a thr...
[ "Products and Processes Engineering" ]
323042
Design Principles of Microtubule Cytoskeleton Architectures during Cell Division
The microtubule cytoskeleton provides an intracellular coordinate system and a mechanical scaffold for a multitude of essential cellular functions. The design principles underlying the dynamic organisation and function of the microtubule cytoskeleton are not understood. Using an in vitro reconstitution approach, we wil...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
885746
Neural origins of mind reading
Human thoughts have no mass and remain definitely hidden from others’ view. Still, we are remarkable at predicting others’ mental states from observable phenomena. Sensitivity to eye cues enables us, for example, to detect the presence of other minds, assess theirs content and interact with them through eye contact, ga...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1016/j.yexcr.2010.07.008
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
The mammalian class III phosphatidylinositol 3-kinase (PI3K-III) complex regulates fundamental cellular functions, including growth factor receptor degradation, cytokinesis and autophagy. Recent studies suggest the existence of distinct PI3K-III sub-complexes that can potentially confer functional specificity. While a ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W1510163937
The Effect of Interest Rate, Inflation and Government Expenditure on Economic Growth in Indonesia Period of 2005- 2012
This study analyzed the effect of interest rates, inflation rates and government spending on economic growth in Indonesia during 2005 to 2012. By using the method of data analysis panel, overall the independent variables namely interest rate, inflation rate and government spending has a 99% influence on the dependent v...
[ "Individuals, Markets and Organisations" ]
10.1167/17.2.12
Different Spatial Representations Guide Eye And Hand Movements
Our visual system allows us to localize objects in the world and plan motor actions toward them. We have recently shown that the localization of moving objects differs between perception and saccadic eye movements (Lisi & Cavanagh, 2015), suggesting different localization mechanisms for perception and action. This find...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
W3102940152
Scalar field cosmologies with inverted potentials
Regular bouncing solutions in the framework of a scalar-tensor gravity model were found in a recent work. We reconsider the problem in the Einstein frame (EF) in the present work. Singularities arising at the limit of physical viability of the model in the Jordan frame (JF) are either of the Big Bang or of the Big Crun...
[ "Universe Sciences", "Fundamental Constituents of Matter" ]
10.1162/NECO_a_00141
On the simulation of nonlinear bidimensional spiking neuron models
Bidimensional spiking models are garnering a lot of attention for their simplicity and their ability to reproduce various spiking patterns of cortical neurons and are used particularly for large network simulations. These models describe the dynamics of the membrane potential by a nonlinear differential equation that b...
[ "Mathematics", "Computer Science and Informatics", "Neuroscience and Disorders of the Nervous System" ]
10.1016/j.cirp.2018.03.005
Ultimate capability of variable pitch milling cutters
Variable pitch milling cutters intend to increase performance, but off-the-shelf cutters do not ensure this generally. Depending on the milling process they are selected for, they can perform better or even worse than uniform pitch cutters do. Improved performance can be guaranteed by considering the reflected dynamic ...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
W4221113285
Rôle des facteurs sociogéographiques dans la participation à un programme de réadaptation cardiaque après une angioplastie coronarienne
La réadaptation cardiaque (RC) après angioplastie coronaire pour syndrome coronarien aigu (SCA) ou chronique (SCC) est sous-utilisée en France, malgré son efficacité démontrée sur la morbi-mortalité et son rapport coût-efficacité favorable. L'objectif était d’étudier, à partir de bases de données de vie réelle, le rôle...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Human Mobility, Environment, and Space", "The Social World and Its Interactions" ]
10.1038/NNANO.2013.240
Detecting The Translocation Of Dna Through A Nanopore Using Graphene Nanoribbons
Solid-state nanopores can act as single-molecule sensors and could potentially be used to rapidly sequence DNA molecules. However, nanopores are typically fabricated in insulating membranes that are as thick as 15 bases, which makes it difficult for the devices to read individual bases. Graphene is only 0. 335 nm thick...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1002/ejhf.801
Circular RNAs in heart failure
Cardiovascular disease, and particularly heart failure, is still a serious health care issue for which novel treatments and biomarkers are needed. The RNA family comprises different subgroups, among which the small-sized microRNAs and the larger long non-coding RNAs have shown some potential to aid in moving personaliz...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1002/ece3.4595
Silk properties and overwinter survival in gregarious butterfly larvae
All organisms are challenged by encounters with parasites, which strongly select for efficient escape strategies in the host. The threat is especially high for gregarious species entering immobile periods, such as diapause. Larvae of the Glanville fritillary butterfly, Melitaea cinxia, spend the winter in diapause in g...
[ "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
IB 2016057748 W
METHOD AND APPARATUS FOR MONITORING VIRTUAL EXTENSIBLE LOCAL AREA NETWORK (VXLAN) TUNNEL WITH BORDER GATEWAY PROTOCOL (BGP)-ETHERNET VIRTUAL PRIVATE NETWORK (EVPN) INFRASTRUCTURE
A method and apparatus for monitoring a status of a virtual extensible local area network (VXLAN) tunnel between a first network device and a second network device are described. A first packet is received from the first network device through the VXLAN tunnel. The first packet includes a network identifier which ident...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1007/978-3-319-62914-8_3
Teichmuller Spaces Of Generalized Hyperelliptic Manifolds
In this paper we answer two questions posed by Catanese (Bull Math Sci 5(3):287–449, 2015), thus achieving in particular a description of the connected components of Teichmuller space corresponding to Generalized Hyperelliptic Manifolds X. These are the quotients X = T∕G of a complex torus T by the free action of a fin...
[ "Mathematics" ]
817533
Post-transcriptional regulation of effector function in T cells by RNA binding proteins
CD8+ T cells are critical to fight infections and to clear tumor cells through the production of inflammatory cytokines and cytotoxic molecules. These effector molecules must be tightly controlled: too little leads to the inability to control the pathogen, and too much can result in a life-threatening cytokine storm an...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
220965
Integrated climate adaptation service tools for improving resilience measure efficiency
Urban areas and traffic infrastructure linking such areas are highly vulnerable to climate change. Smart use of existing climate intelligence can increase urban resilience and generate added value for businesses and society at large. Based on the results of FP7 climate change, future internet and crisis preparedness ...
[ "Earth System Science", "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1038/ismej.2015.80
Local adaptation constrains the distribution potential of heat-tolerant Symbiodinium from the Persian/Arabian Gulf
The symbiotic association of corals and unicellular algae of the genus Symbiodinium in the southern Persian/Arabian Gulf (PAG) display an exceptional heat tolerance, enduring summer peak temperatures of up to 36 °C. As yet, it is not clear whether this resilience is related to the presence of specific symbiont types th...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1093/cercor/bhr191
Heterogeneous spine loss in layer 5 cortical neurons after spinal cord injury
A large thoracic spinal cord injury disconnects the hindlimb (HL) sensory-motor cortex from its target, the lumbar spinal cord. The fate of the synaptic structures of the axotomized cortical neurons is not well studied. We evaluated the density of spines on axotomized corticospinal neurons at 3, 7, and 21 days after th...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1063/1.4861003
Analytic Cubic And Quartic Force Fields Using Density Functional Theory
We present the first analytic implementation of cubic and quartic force constants at the level of Kohn–Sham density-functional theory. The implementation is based on an open-ended formalism for the evaluation of energy derivatives in an atomic-orbital basis. The implementation relies on the availability of open-ended c...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1039/c8nr07667g
Cancer cell targeting and therapeutic delivery of silver nanoparticles by mesoporous silica nanocarriers: Insights into the action mechanisms using quantitative proteomics
An approach for safely delivering AgNPs to cancer cells and the evaluation of the affected cellular mechanism are presented. The use of mesoporous silica nanoparticles (MSNs) as nanovehicles decorated with transferrin (Tf, targeting agent) provides a nanoplatform for the nucleation and immobilization of AgNPs (MSNs-Tf-...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1016/j.gca.2014.07.014
Adsorption and desorption of arsenic to aquifer sediment on the Red River floodplain at Nam Du, Vietnam
The adsorption of arsenic onto aquifer sediment from the Red River floodplain, Vietnam, was determined in a series of batch experiments. Due to water supply pumping, river water infiltrates into the aquifer at the field site and has leached the uppermost aquifer sediments. The leached sediments remain anoxic but contai...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
W2748540641
Intrinsic self-healing polymers with a high E-modulus based on dynamic reversible urea bonds
One of the hardest self-healing polymers ever reported has been prepared using the reversible bonds of sterically hindered urea groups. Polymers that can re-form internal chemical links after being scratched or cracked are usually subject to design constraints that lower their mechanical strength. To overcome these con...
[ "Materials Engineering", "Synthetic Chemistry and Materials" ]
W2064866962
A CFD study of biomass pyrolysis in a downer reactor equipped with a novel gas–solid separator — I: Hydrodynamic performance
This study presents the first part of a CFD study on the performance of a downer reactor for biomass pyrolysis. The reactor was equipped with a novel gas-solid separation method, developed by the co-authors from the ICFAR (Canada). The separator, which was designed to allow for fast separation of clean pyrolysis gas, c...
[ "Products and Processes Engineering", "Physical and Analytical Chemical Sciences" ]
10.1016/j.jasrep.2016.06.028
The use of close-range photogrammetry in zooarchaeology: Creating accurate 3D models of wolf crania to study dog domestication
Close-range photographic techniques - including photogrammetry - are becoming common tools for constructing three-dimensional (3D) models of artifacts, particularly in archaeological research. Whether models obtained through photogrammetry can be used for zooarchaeological studies requires a systematic examination. In ...
[ "The Study of the Human Past", "Computer Science and Informatics" ]
10.1142/S0219498813501211
A Note On Nil And Jacobson Radicals In Graded Rings
It was shown by Bergman that the Jacobson radical of a Z-graded ring is homogeneous. This paper shows that the analogous result holds for nil radicals, namely, that the nil radical of a Z-graded ring is homogeneous. It is obvious that a subring of a nil ring is nil, but generally a subring of a Jacobson radical ring ne...
[ "Mathematics" ]
10.1007/JHEP03(2015)085
Wilson Loops And Minimal Surfaces Beyond The Wavy Approximation
We study Euclidean Wilson loops at strong coupling using the AdS/CFT correspondence, where the problem is mapped to finding the area of minimal surfaces in Hyperbolic space. We use a formalism introduced recently by Kruczenski to perturbatively compute the area corresponding to boundary contours which are deformations ...
[ "Fundamental Constituents of Matter", "Mathematics" ]
10.1039/c7nr05994a
Efficient electro-optic modulation in low-loss graphene-plasmonic slot waveguides
Surface plasmon polaritons enable light concentration within subwavelength regions, and here we demonstrate efficient and compact graphene-plasmonic modulators fully integrated in the silicon-on-insulator platform.
[ "Condensed Matter Physics", "Systems and Communication Engineering", "Synthetic Chemistry and Materials" ]
10.1371/journal.pcbi.1004685
Implementation of Complex Biological Logic Circuits Using Spatially Distributed Multicellular Consortia
Engineered synthetic biological devices have been designed to perform a variety of functions from sensing molecules and bioremediation to energy production and biomedicine. Notwithstanding, a major limitation of in vivo circuit implementation is the constraint associated to the use of standard methodologies for circuit...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering", "Computer Science and Informatics" ]
10.1039/c6em00697c
Eawag-Soil in enviPath: a new resource for exploring regulatory pesticide soil biodegradation pathways and half-life data
Eawag-Soil offers an extensive collection of data on pesticide soil degradation pathways and half-lives for diverse uses, including QSBR development.
[ "Environmental Biology, Ecology and Evolution", "Physical and Analytical Chemical Sciences" ]
W4205409966
Severe alcoholic hepatitis as precipitant for organ failure and ACLF
Alcoholic hepatitis is the acute deterioration of alcoholic liver disease with rapid onset or worsening of jaundice, which in severe cases, may transition to acute-on-chronic liver failure with extremely high short-term mortality, increasing with the number and severity of hepatic and extra-hepatic organ dysfunction. D...
[ "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1002/jmr.2527
Antibody humanization by molecular dynamics simulations - In-silico guided selection of critical backmutations
Monoclonal antibodies represent the fastest growing class of biotherapeutic proteins. However, as they are often initially derived from rodent organisms, there is a severe risk of immunogenic reactions, hampering their applicability. The humanization of these antibodies remains a challenging task in the context of rati...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Computer Science and Informatics" ]
10.1039/c8nr01622d
A gold-nanoparticle stoppered [2]rotaxane
A gold-nanoparticle stoppered [2]rotaxane based on a stable pseudo-rotaxane featuring an electroactive ferrocene rod encapsulated in a cucurbit[7]uril macrocycle is described.
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1371/journal.pone.0214510
Why ruminating ungulates chew sloppily: Biomechanics discern a phylogenetic pattern
There is considerable debate regarding whether mandibular morphology in ungulates primarily reflects phylogenetic affinities or adaptation to specific diet. In an effort to help resolve this debate, we use three-dimensional finite element analysis (FEA) to assess the biomechanical performance of mandibles in eleven ung...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution" ]
W4211024852
Adapter les territoires au risque d’inondation en France et en Espagne : vers de nouvelles pratiques d’aménagement des zones inondables ?
L’injonction actuelle à l’adaptation des territoires au changement climatique et à ses effets ne contribue-t-elle pas à l’émergence de nouvelles formes d’aménagement des zones exposées au risque d’inondation par débordement de cours d’eau ou submersion marine, via le développement de nouvelles pratiques opérationnelles...
[ "Earth System Science", "Human Mobility, Environment, and Space", "Products and Processes Engineering", "Institutions, Governance and Legal Systems" ]
US 73463776 A
FUNNELING MACHINE WITH INCLINED ADVANCING RAMS
A vehicle for use in mine workings for enlarging a tunnel or for forming a heading and comprising a wheeled chassis having a rock breaker and a bucket loader mounted thereon further includes a conveyor means extending generally longitudinally of the chassis to receive rock and spoil collected by the bucket loader at th...
[ "Products and Processes Engineering" ]
interreg_1175
ENERGY@SCHOOL: ENERGY OPTIMIZATION AND BEHAVIUOR CHANGE INTO SCHOOLS OF CENTRAL EUROPE
The building sector has high potential for energy optimization being the most consuming one in EU. In terms of public buildings heritage, energy consumption in schools is the second highest expenditure of Municipalities total running costs. This sector offers potential remarkable achievements in terms of EE, RES applic...
[ "Products and Processes Engineering", "Earth System Science", "The Social World and Its Interactions" ]
10.1177/2041731420945633
A Miniaturized Hydrogel Based In Vitro Model For Dynamic Culturing Of Human Cells Overexpressing Beta Amyloid Precursor Protein
Recent findings have highlighted an interconnection between intestinal microbiota and the brain, referred to as microbiota-gut-brain axis, and suggested that alterations in microbiota composition might affect brain functioning, also in Alzheimer's disease. To investigate microbiota-gut-brain axis biochemical pathways, ...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1039/c4lc00985a
A droplet microfluidic system for sequential generation of lipid bilayers and transmembrane electrical recordings
We report a droplet microfluidic system that automates the formation of lipid bilayers and allows for electrophysiological measurements and for an automated screening protocols in which the activity of proteins is tested against inhibitors.
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1016/j.coi.2010.12.017
Signaling in thymic selection
T cell receptor signaling allows the developing thymocyte to undergo positive or negative selection, which is required for the formation of a useful mature T cell repertoire. Recent developments include the finding that much of the Lck kinase (required to initiate T cell signaling) is already in an active configuration...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1007/978-3-030-01449-0_47
Fast Light Field Inpainting Propagation Using Angular Warping And Color Guided Disparity Interpolation
This paper describes a method for fast and efficient inpainting of light fields. We first revisit disparity estimation based on smoothed structure tensors and analyze typical artefacts with their impact for the inpainting problem. We then propose an approach which is computationally fast while giving more coherent disp...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1080/13608746.2016.1199091
Social Movements Within Organisations Occupy Parties In Italy And Turkey
AbstractThis paper analyses a little-studied phenomenon: movements within parties. While parties and movements are often assumed to be separate entities, the borders between the two have proved to be more fluent. Parties frequently play a pivotal role in movement politics, and movements influence parties through the du...
[ "The Social World and Its Interactions", "Institutions, Governance and Legal Systems" ]
W2766464963
Social hair pulling in captive rhesus macaques (Macaca mulatta)
Alopecia is common among captive populations of nonhuman primates. There are many potential causes of alopecia, including physiological conditions such as hormonal imbalance and infection, features of the captive environment such as housing type, ground substrate, and group density, as well as behavioral abnormalities ...
[ "Environmental Biology, Ecology and Evolution", "Physiology in Health, Disease and Ageing" ]
10.1007/s11538-013-9924-4
Travelling Waves in Hybrid Chemotaxis Models
Hybrid models of chemotaxis combine agent-based models of cells with partial differential equation models of extracellular chemical signals. In this paper, travelling wave properties of hybrid models of bacterial chemotaxis are investigated. Bacteria are modelled using an agent-based (individual-based) approach with in...
[ "Mathematics", "Physical and Analytical Chemical Sciences" ]
10.7554/eLife.18146
Intramuscular neurotrophin-3 normalizes low threshold spinal reflexes, reduces spasms and improves mobility after bilateral corticospinal tract injury in rats
Brain and spinal injury reduce mobility and often impair sensorimotor processing in the spinal cord leading to spasticity. Here, we establish that complete transection of corticospinal pathways in the pyramids impairs locomotion and leads to increased spasms and excessive mono-and polysynaptic low threshold spinal refl...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1007/s11403-017-0201-8
Much ado about making money: the impact of disclosure, news and rumors on the formation of security market prices over time
This article develops an agent-based model of security market pricing process, capable to capture main stylised facts. It features collective market pricing mechanisms based upon evolving heterogenous expectations that incorporate signals of security issuer fundamental performance over time. Distinctive signaling sourc...
[ "Individuals, Markets and Organisations", "Computer Science and Informatics" ]
10.1111/jeb.12621
The locus of sexual selection: Moving sexual selection studies into the post-genomics era
Sexual selection drives fundamental evolutionary processes such as trait elaboration and speciation. Despite this importance, there are surprisingly few examples of genes unequivocally responsible for variation in sexually selected phenotypes. This lack of information inhibits our ability to predict phenotypic change d...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.7554/elife.48182
A neural mechanism for contextualizing fragmented inputs during naturalistic vision
With every glimpse of our eyes, we sample only a small and incomplete fragment of the visual world, which needs to be contextualized and integrated into a coherent scene representation. Here we show that the visual system achieves this contextualization by exploiting spatial schemata, that is our knowledge about the co...
[ "Neuroscience and Disorders of the Nervous System", "Computer Science and Informatics" ]
10.1007/978-3-662-49896-5_25
Fair And Robust Multi Party Computation Using A Global Transaction Ledger
Classical results on secure multi-party computation MPC imply that fully secure computation, including fairness either all parties get output or none and robustness output delivery is guaranteed, is impossible unless a majority of the parties is honest. Recently, cryptocurrencies like Bitcoin where utilized to leverage...
[ "Computer Science and Informatics" ]
W1935693849
Reeb orbits and the minimal discrepancy of an isolated singularity
Let A be an affine variety inside a complex N dimensional vector space which has an isolated singularity at the origin. The intersection of A with a very small sphere turns out to be a contact manifold called the link of A. Any contact manifold contactomorphic to the link of A is said to be Milnor fillable by A. If the...
[ "Mathematics" ]
W2263881055
Age distribution of abnormal pap smear in a secondary hospital in south-west Nigeria
Background : Cervical cancer is a leading cause of cancer death in Sub- Saharan Africa. It is the second commonest cancer in women worldwide. The prevalence of the disease has reduced in developed nations compared to most developing nations as a result of systematic screening programmes. There is no age distribution pa...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
10.1051/0004-6361/202037957
Vector Speckle Grid Instantaneous Incoherent Speckle Grid For High Precision Astrometry And Photometry In High Contrast Imaging
Photometric and astrometric monitoring of directly imaged exoplanets will deliver unique insights into their rotational periods, the distribution of cloud structures, weather, and orbital parameters. As the host star is occulted by the coronagraph, a speckle grid (SG) is introduced to serve as astrometric and photometr...
[ "Physical and Analytical Chemical Sciences", "Universe Sciences" ]
221286
Circulating tumor cells for tailoring bmp targeted therapies
Gastro-intestinal (GI) cancers, including gastro-esophageal junctional (GEJC), gastric (GC), colorectal (CRC) and pancreatic cancer (PC) are devastating malignancies that annually affect over 2 million persons worldwide and lead to more than 600,000 deaths (Globocan 2012). Given the current trends, the incidence of GI ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1146/annurev-cellbio-111315-124936
Regulation of Hematopoiesis and Osteogenesis by Blood Vessel-Derived Signals
In addition to their conventional role as a versatile transport system, blood vessels provide signals controlling organ development, regeneration, and stem cell behavior. In the skeletal system, certain capillaries support perivascular osteoprogenitor cells and thereby control bone formation. Blood vessels are also a c...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1103/PhysRevB.93.235144
History dependence of the magnetic properties of single-crystal Fe1-xCoxSi
We report the magnetization, ac susceptibility, and specific heat of optically float-zoned single crystals of Fe1-xCoxSi, 0. 20≤x≤0. 50. We determine the magnetic phase diagrams for all major crystallographic directions and cooling histories. After zero-field cooling, the phase diagrams resemble that of the archetypal ...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1515/ling-2016-0035
Cross-linguistic patterns in the structure, function, and position of (object) complement clauses
AbstractThe present contribution examines object complement clauses from the perspective of constituent-order typology. In particular, it provides the first principled empirical investigation of the position of object clauses relative to the matrix verb. Based on a stratified sample of 100 languages, we establish that ...
[ "The Human Mind and Its Complexity" ]
10.1051/0004-6361/201834523
Discovery Of A Directly Imaged Disk In Scattered Light Around The Sco Cen Member Wray 15 788
As part of our on-going survey we have carried out high-contrast imaging with VLT/SPHERE/IRDIS to obtain polarized and total intensity images of the young ($11^{+16}_{-7}$Myr old) K3IV star Wray 15-788 within the Lower Centaurus Crux subgroup of Sco-Cen. For the total intensity images, we remove the stellar halo by an ...
[ "Universe Sciences" ]
10.1038/nn.4531
Cerebellar granule cells acquire a widespread predictive feedback signal during motor learning
Cerebellar granule cells, which constitute half the brain's neurons, supply Purkinje cells with contextual information necessary for motor learning, but how they encode this information is unknown. Here we show, using two-photon microscopy to track neural activity over multiple days of cerebellum-dependent eyeblink con...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
interreg_1251
European Rural Futures - New opportunities to secure the provision of public services in rural cities and municipalities
Most of the European rural areas are facing the problem of shrinking population and a significant increase in the proportion of elderly residents; associated with related challenges like; increasing costs for provision and maintenance of public services and infrastructure, changes within the economic situation of commu...
[ "Human Mobility, Environment, and Space", "Individuals, Markets and Organisations" ]
W2012142967
Gendering constitutional change and policy outcomes: substantive representation and domestic violence policy in Scotland
Scotland bears many hallmarks of a case of successful feminist constitutional activism: high levels of women’s descriptive representation in the devolved parliament and a gender-inclusive institutional design mutually reinforced one another, opening up the political process. In this article domestic violence policy is ...
[ "The Social World and Its Interactions", "Institutions, Governance and Legal Systems" ]
10.1093/cercor/bhz110
Auditory and Semantic Cues Facilitate Decoding of Visual Object Category in MEG
Sounds (e. g. , barking) help us to visually identify objects (e. g. , a dog) that are distant or ambiguous. While neuroimaging studies have revealed neuroanatomical sites of audiovisual interactions, little is known about the time course by which sounds facilitate visual object processing. Here we used magnetoencephal...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1596/978-1-4648-1274-3
Maritime Networks Port Efficiency And Hinterland Connectivity In The Mediterranean
For millennia, the Mediterranean has been one of the most active trading areas, supported by a transport network connecting riparian cities and beyond to their hinterland. The Mediterranean has complex trade patterns and routes--but with key differences from the past. It is no longer an isolated world economy: it is bo...
[ "Individuals, Markets and Organisations", "Human Mobility, Environment, and Space" ]
10.1134/S0965542513020103
Geometric Numerical Schemes For The Kdv Equation
Geometric discretizations that preserve certain Hamiltonian structures at the discrete level has been proven to enhance the accuracy of numerical schemes. In particular, numerous symplectic and multi-symplectic schemes have been proposed to solve numerically the celebrated Korteweg-de Vries equation. In this work, we s...
[ "Mathematics", "Computer Science and Informatics" ]
805098
Beyond Eureka: The Foundations of Japan's Industrialization, 1800-1885
Beyond Eureka seeks to challenge current understanding of how Japan became a global industrial power along with the model of how innovation takes place. Japan was the first Asian nation to industrialize and in a space of several decades went from a relatively isolated agrarian economy to an industrialized nation. The k...
[ "The Study of the Human Past", "The Social World and Its Interactions" ]
W1941231029
Local moving least square-one-dimensional integrated radial basis function networks technique for incompressible viscous flows
This paper presents a local moving least square-one-dimensional integrated radial basis function networks method for solving incompressible viscous flow problems using stream function-vorticity formulation. In this method, the partition of unity method is employed as a framework to incorporate the moving least square ...
[ "Mathematics", "Products and Processes Engineering" ]
10.1002/bies.201600203
Indole: An evolutionarily conserved influencer of behavior across kingdoms
Indole is a key environmental cue that is used by many organisms. Based on its biochemistry, we suggest indole is used so universally, and by such different organisms, because it derives from the metabolism of tryptophan, a resource essential for many species yet rare in nature. These properties make it a valuable, env...
[ "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]