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224601
Networking, partnerships and tools to enhance in situ conservation of european plant genetic resources
The overarching objective of Farmer’s Pride is to establish a network of stakeholders and conservation sites that effectively coordinates conservation actions to safeguard the wealth of Europe’s in situ plant genetic resources (PGR) and integrates the user community to maximize their sustainable use. Specifically, to a...
[ "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering", "Institutions, Governance and Legal Systems" ]
227458
Operator Algebras and Conformal Field Theory
The project has two fundamental aims: A) Open new research horizons exploiting the interplay between Operator Algebras and Conformal Quantum Field Theory. B) Use Operator Algebraic methods for a deeper understanding of the internal structure of Conformal Quantum Field Theory, with a possible feedback for Operator ...
[ "Fundamental Constituents of Matter", "Mathematics" ]
10.1038/nature12187
Cloning of Dirac fermions in graphene superlattices
Superlattices have attracted great interest because their use may make it possible to modify the spectra of two-dimensional electron systems and, ultimately, create materials with tailored electronic properties. In previous studies (see, for example, refs 1, 2, 3, 4, 5, 6, 7, 8), it proved difficult to realize superlat...
[ "Condensed Matter Physics", "Materials Engineering" ]
W1480571106
The Optimal Version of Hua's Fundamental Theorem of Geometry of Rectangular Matrices
Hua's fundamental theorem of geometry of matrices describes the general form of bijective maps on the space of all mi?½n matrices over a division ring D which preserve adjacency in both directions. Motivated by several applications the author studies a long standing open problem of possible improvements. There are thre...
[ "Mathematics" ]
interreg_61
Improving accessibility of services of general interest – organisational innovations in rural mountain areas
The maintainance of a spatially and socially equal accessibility to services of general interest (SGI) is a core issue to the functionality of mountain areas. However, the ongoing territorial concentration of SGI leads to a vicious circle of further deterioration in the quality of provision which in turn causes a decre...
[ "Human Mobility, Environment, and Space", "Individuals, Markets and Organisations" ]
US 2004/0004593 W
POLY ALCOHOL-BASED BINDER COMPOSITION
The present invention provides a binder composition comprising a low molecular weight polycarboxylic acid, such as maleic anhydride, and a low molecular weight poly alcohol, such as polyvinyl alcohol, that exhibits improved cure performance with reduced emissions without sacrificing the performance of the final product...
[ "Synthetic Chemistry and Materials", "Materials Engineering" ]
898715
Developing inclusive & sustainable creative economies
The DISCE (Developing Inclusive & Sustainable Creative Economies) project is set to improve and enhance the growth, inclusivity and sustainability of the cultural and creative industries (CCIs) in the EU. Overall, the ambitious objectives of DISCE are: i) to support the development patterns of CCIs within the EU throug...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems", "The Social World and Its Interactions", "Studies of Cultures and Arts" ]
10.1038/ncomms8119
Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain
The rise of drug-resistant strains is a major challenge to containing the tuberculosis (TB) pandemic. Yet, little is known about the extent of resistance in early years of chemotherapy and when transmission of resistant strains on a larger scale became a major public health issue. Here we reconstruct the timeline of th...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1007/s11098-014-0370-4
Backwards in Retrospect
In the title chapter of Did Darwin Write the Origin Backwards?, Sober argues for an asymmetry between facts about genealogy and facts about natural selection, which has the result that evidentially (but not causally) Darwin's book is the wrong way round. Here I make three points about Sober's argument in that chapter. ...
[ "Texts and Concepts" ]
10.1016/j.celrep.2018.08.032
GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation
Hypertrophic white adipose tissue (WAT) represents a maladaptive mechanism linked to the risk for developing type 2 diabetes in humans. However, the molecular events that predispose WAT to hypertrophy are poorly defined. Here, we demonstrate that adipocyte hypertrophy is triggered by loss of the corepressor GPS2 during...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Integrative Biology: from Genes and Genomes to Systems", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1039/d0cc03779f
Steering alkyne homocoupling with on-surface synthesized metal–organic complexes
Multi-step on-surface synthesis: surface-supported synthesis of metal–organic complexes to control subsequent alkyne homocoupling reactions.
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.3389/fmolb.2017.00008
Unveiling the metabolic changes on muscle cell metabolism underlying p-phenylenediamine toxicity
Rhabdomyolysis is a disorder characterized by acute damage of the sarcolemma of the skeletal muscle leading to release of potentially toxic muscle cell components into the circulation, most notably creatine phosphokinase (CK) and myoglobulin, and is frequently accompanied by myoglobinuria. In the present work, we evalu...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Integrative Biology: from Genes and Genomes to Systems", "Cell Biology, Development, Stem Cells and Regeneration" ]
W2348246401
A Refined Spatial Division of Freezing Injury to Litchi Base on Digital Elevation Model:A Case from Zhangzhou
The spatial models about winter extreme low temperature and 4 levels'(-2 Td≤0℃,-3 Td≤-2℃,-4 Td≤-3℃,Td -4℃) cold damage model were built,by using stepwise regression analysis and GIS technology,then the planting areas of Litchi in Zhangzhou were divided according to the grading index.The result showed that:1) the planti...
[ "Earth System Science", "Computer Science and Informatics" ]
10.1109/ACCESS.2017.2776083
Adaptive Transceiver Design For C Ran In Mmwave Communications
An adaptive array design is proposed for hybrid beamforming in millimeter-wave (mmWave) communications in the context of cloud radio access networks (C-RAN). More explicitly, the adaptive design focuses on the physical layer aspect of C-RAN. The adaptation is performed at two levels, depending on whether the channel is...
[ "Systems and Communication Engineering" ]
948528
Tracing epigenetic evolution of triple-negative breast cancer towards chemo-resistance
The emergence of resistance to chemotherapy and targeted therapies is a major challenge for the treatment of cancer. While several genetic mechanisms driving resistance processes have been discovered, non-genetic mechanisms have also been shown to contribute to drug resistance. Yet, our restricted understanding of epig...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems", "Physiology in Health, Disease and Ageing" ]
W3097255860
Impact of inorganic, organic and bio-fertilizers on growth and yield of guava (Psidium guajava L.)
Guava is an important fruit crop with regards to its nutritional and commercial value. Production and productivity are the prime concern of the researchers and farmers throughout the world. Looking to the cumulative toxic effects of inorganic fertilizers and chemicals used in maximizing the production and productivity,...
[ "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering" ]
10.1016/j.spa.2017.03.008
On the asymptotic normality of estimating the affine preferential attachment network models with random initial degrees
We consider the estimation of the affine parameter and power-law exponent in the preferential attachment model with random initial degrees. We derive the likelihood, and show that the maximum likelihood estimator (MLE) is asymptotically normal and efficient. We also propose a quasi-maximum-likelihood estimator (QMLE) t...
[ "Mathematics", "Computer Science and Informatics" ]
10.1090/memo/1206
Mathematical study of degenerate boundary layers: A large scale ocean circulation problem
This paper is concerned with a complete asymptotic analysis as E → 0 of the stationary Munk equation ∂xψ - EΔ2ψ = τ in a domain Ω ⊂ R2, supplemented with boundary conditions for ψ and ∂nψ. This equation is a simple model for the circulation of currents in closed basins, the variables x and y being respectively the long...
[ "Mathematics", "Earth System Science" ]
819179
Canonical and Non-canonical modes of Chromosome Segregation in Oocyte Meiosis
Cell division is crucial for the development of complex organisms, for the homeostasis of tissues, and for the reproductive capacity of individuals. While most somatic cells are diploid and proliferate through mitosis, multiplication of sexually reproducing species relies on haploid gametes that are generated through a...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
FR 2010052923 W
FLOOR
The invention relates to a floor (1) including a plurality of beams (2) and a screed (5) that is located above said beams, characterized in that said floor includes at least one casing (3), held by two of said adjacent beams, and an interjoist (4), held by said casing, said casing and said interjoist defining a space t...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1016/j.celrep.2016.11.003
Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development
Lymphocytes represent basic components of vertebrate adaptive immune systems, suggesting the utility of non-mammalian models to define the molecular basis of their development and differentiation. Our forward genetic screens in zebrafish for recessive mutations affecting early T cell development revealed several major ...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1016/bs.mcb.2015.06.010
Isolation and analyses of axonal ribonucleoprotein complexes
Cytoskeleton-dependent RNA transport and local translation in axons are gaining increased attention as key processes in the maintenance and functioning of neurons. Specific axonal transcripts have been found to play roles in many aspects of axonal physiology including axon guidance, axon survival, axon to soma communic...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1039/C3OB26251K
Protein Destabilisation By Ruthenium Ii Tris Bipyridine Based Protein Surface Mimetics
Highly functionalised ruthenium(II) tris-bipyridine receptor 1 which acts as a selective sensor for equine cytochrome c (cyt c) is shown to destabilise the native protein conformation by around 25 °C. Receptors 2 and 3 do not exert this effect confirming the behaviour is a specific effect of molecular recognition betwe...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1038/nature16059
Undecidability of the spectral gap
The spectral gap - the energy difference between the ground state and first excited state of a system - is central to quantum many-body physics. Many challenging open problems, such as the Haldane conjecture, the question of the existence of gapped topological spin liquid phases, and the Yang-Mills gap conjecture, conc...
[ "Condensed Matter Physics", "Mathematics" ]
10.1103/PhysRevB.95.134433
Voltage-controlled nanoscale reconfigurable magnonic crystal
A nanoscale reconfigurable magnonic crystal is designed using voltage-controlled perpendicular magnetic anisotropy (PMA) in ferromagnetic-dielectric heterostructures. A periodic array of gate metallic strips is placed on top of a MgO/Co structure in order to apply a periodic electric field and to modify the PMA in Co. ...
[ "Condensed Matter Physics", "Materials Engineering", "Systems and Communication Engineering" ]
10.1038/srep16571
Disease-induced resource constraints can trigger explosive epidemics
Advances in mathematical epidemiology have led to a better understanding of the risks posed by epidemic spreading and informed strategies to contain disease spread. However, a challenge that has been overlooked is that, as a disease becomes more prevalent, it can limit the availability of the capital needed to effectiv...
[ "Mathematics", "Prevention, Diagnosis and Treatment of Human Diseases", "Immunity, Infection and Immunotherapy" ]
EP 95112649 A
Spray apparatus for bottle cleaning machine
The arrangement incorporates a tube (1) to which cleaning fluid is fed under pressure. A shaft is mounted at a short distance from and parallel with the tube. The shaft is supported by bearing blocks (3) on the tube. Spray holes (5) in the shaft are connected to the tube by plastics seals (6) which are mounted between ...
[ "Products and Processes Engineering", "Materials Engineering" ]
W1981287510
Single-Incision Sleeve Gastrectomy Using a Novel Technique for Liver Retraction
INTRODUCTION Laparoscopic sleeve gastrectomy has rapidly gained popularity in the field of bariatric surgery, mainly due to its low morbidity and mortality. Traditionally, 4 to 6 trocars are used. Single-access surgery has emerged as an attempt to decrease incisional morbidity and enhance cosmetic benefits. We present ...
[ "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2038787158
Synthesis of 2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide-based azetidinone derivatives as potent antibacterial and antifungal agents
Twelve compounds belonging to series N-[3-chloro-2-oxo-4-(substituted)phenylazetidin-1-yl]-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide (5a–l) were synthesized. These compounds were evaluated for their in vitro antibacterial against E. coli, S. aureus, K. pneumoniae, P. aeruginosa and antifungal activity against C. a...
[ "Synthetic Chemistry and Materials", "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W1647496226
P-glycoprotein(ABCB1)inhibited network of mitochondrion transport along microtubule and BMP signal-induced cell shape in chimpanzee left cerebrum by systems-theoretical analysis
We constructed the significant low-expression P-glycoprotein (ABCB1) inhibited transport and signal network in chimpanzee compared with high-expression (fold change ≥2) the human left cerebrum in GEO data set, by using integration of gene regulatory activated and inhibited network inference method with gene ontology (G...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.4476/73599
Philosophical Issues In Transitional Justice Theory A Provisional Balance
Transitional justice is becoming more and more an interdisciplinary field of study with interesting developments, not only in the assessment of a wide number of casestudies, but also in the evaluation of increasingly more articulated theoretical problems. Undoubtedly, a robust collection of literature has now accumulat...
[ "Texts and Concepts", "Institutions, Governance and Legal Systems" ]
W374401512
Educational Innovation in the Computer Architecture Area
Abstract In the present work authors give a detailed description of the previously performed analysis carried out to formulate a concrete educational innovation project proposal in the area of the Computer Architecture, more specifically, in the Computer Structure and Architecture sub-module. That project was submitted...
[ "Computer Science and Informatics", "The Social World and Its Interactions" ]
10.1021/bk-2019-1326.ch001
Atomic-Scale Representation and Statistical Learning of Tensorial Properties
This chapter discusses the importance of incorporating three-dimensional symmetries in the context of statistical learning models geared towards the interpolation of the tensorial properties of atomic-scale structures. We focus on Gaussian process regression, and in particular on the construction of structural represen...
[ "Physical and Analytical Chemical Sciences", "Mathematics", "Computer Science and Informatics" ]
10.1038/nbt.2942
An integrated catalog of reference genes in the human gut microbiome
Many analyses of the human gut microbiome depend on a catalog of reference genes. Existing catalogs for the human gut microbiome are based on samples from single cohorts or on reference genomes or protein sequences, which limits coverage of global microbiome diversity. Here we combined 249 newly sequenced samples of th...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1016/j.actamat.2015.08.047
Deformation mechanism of ω-enriched Ti-Nb-based gum metal: Dislocation channeling and deformation induced ω-β transformation
Gum metal, a class of multifunctional β titanium alloys, has attracted much attention in the past decade due to its initially-proposed dislocation-free deformation mechanism based on giant faults, i. e. , macroscopic planar defects carrying significant plastic strain. Special deformation features were observed in these...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1177/2167702616658634
Social Acknowledgment Of Violent Experiences And Its Role In Ptsd And Appetitive Aggression Among High Risk Males In South Africa
Violence exposure poses a risk for posttraumatic stress disorder (PTSD) and appetitive aggression. Does acknowledgment of violent experiences by one’s social environment also affect these adverse c. . .
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity" ]
10.1126/sciadv.aba8526
Highly energy-tunable quantum light from moiré-trapped excitons
Photon antibunching, a hallmark of quantum light, has been observed in the correlations of light from isolated atomic and atomic-like solid-state systems. Two-dimensional semiconductor heterostructures offer a unique method to create a quantum light source: Moiré trapping potentials for excitons are predicted to create...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Fundamental Constituents of Matter" ]
Q4867333
DEVELOPMENT OF INNOVATIVE CONNECTION TECHNOLOGIES WITH ANTI-SEISMIC CHARACTERISTICS (SITECA)
EDILMATIC PRODUCES ANCHORING SYSTEMS INTENDED FOR THE ASSEMBLY OF PREFABRICATED ELEMENTS FOR BOTH TRADITIONAL AND INDUSTRIALISED CONSTRUCTION, WITH PARTICULAR ATTENTION TO ANTISISMICHE CHARACTERISTICS.THE PROJECT COVERED BY THIS APPLICATION IS AN EXPERIMENTAL DEVELOPMENT PROJECT INHERENT IN THE DEVELOPMENT AND EXPERIME...
[ "Products and Processes Engineering", "Materials Engineering" ]
W1156714629
Role of Animal Models in Coronary Stenting
Coronary angioplasty initially employed balloon dilatation only. This technique revolutionized the treatment of coronary artery disease, although outcomes were compromised by acute vessel closure, late constrictive remodeling, and restenosis due to neointimal proliferation. These processes were studied in animal models...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Products and Processes Engineering", "Materials Engineering" ]
10.1257/jep.30.3.141
Mindful Economics: The Production, Consumption, and Value of Beliefs
In this paper, we provide a perspective into the main ideas and findings emerging from the growing literature on motivated beliefs and reasoning. This perspective emphasizes that beliefs often fulfill important psychological and functional needs of the individual. Economically relevant examples include confidence in on...
[ "Individuals, Markets and Organisations", "The Human Mind and Its Complexity" ]
10.1145/3341692
Approximate Normalization For Gradual Dependent Types
Dependent types help programmers write highly reliable code. However, this reliability comes at a cost: it can be challenging to write new prototypes in (or migrate old code to) dependently-typed programming languages. Gradual typing makes static type disciplines more flexible, so an appropriate notion of gradual depen...
[ "Computer Science and Informatics" ]
10.1007/978-94-007-0735-1_5
The Particle Finite Element Method For Multi Fluid Flows
This paper presents the Particle Finite Element Method (PFEM) and its application to multi-fluid flows. Key features of the method are the use of a Lagrangian description to model the motion of the fluid particles (nodes) and that all the information is associated to the particles. A mesh connects the nodes defining th...
[ "Mathematics", "Computer Science and Informatics", "Condensed Matter Physics", "Products and Processes Engineering" ]
EP 96309442 A
Debug apparatus and method for debugging game program in ROM cartridge
In a developing environment, a game program exists in a product ROM and a debug program exists in another ROM which is a test ROM. The debug program includes a time adjusting program and cther debug routine programs. The game program includes some statements for the debug program. When a ROM cartridge is produced as a ...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1103/PhysRevLett.108.175502
Dynamics and dissipation induced by single-electron tunneling in carbon nanotube nanoelectromechanical systems
We demonstrate the effect of single-electron tunneling (SET) through a carbon nanotube quantum dot on its nanomechanical motion. We find that the frequency response and the dissipation of the nanoelectromechanical system to SET strongly depends on the electronic environment of the quantum dot, in particular, on the tot...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
866345
Exploiting the DNA damage response to induce degradation of proteins
Here I propose to use small molecules to degrade proteins specifically around sites of DNA damage by using the damage itself as a homing signal. The approach will create new ways to study DNA damage, but will also offer translational possibilities in cancer. Cancer cells are often acutely sensitive to DNA damage becaus...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1371/journal.pone.0029557
Intentional binding is driven by the mere presence of an action and not by motor prediction
Intentional binding refers to the fact that when a voluntary action produces a sensory outcome, action and outcome are perceived as being closer together in time. This phenomenon is often attributed, at least partially, to predictive motor mechanisms. However, previous studies failed to unequivocally attribute intentio...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1021/acs.chemrev.8b00304
Asymmetric Preparation of Polysubstituted Cyclopropanes Based on Direct Functionalization of Achiral Three-Membered Carbocycles
In addition to the appealing synthetic transformations that cyclopropanes present, they are also part of larger molecular structures that possess a wide range of biological properties. Therefore, the preparation of enantiomerically enriched cyclopropanes has consistently been a very interesting research topic in organi...
[ "Synthetic Chemistry and Materials" ]
10.1016/j.celrep.2014.05.054
Control of disease tolerance to malaria by nitric oxide and carbon monoxide
Nitric oxide (NO) and carbon monoxide (CO) are gasotransmitters that suppress the development of severe forms of malaria associated with Plasmodium infection. Here, we addressed the mechanism underlying their protective effect against experimental cerebral malaria (ECM), a severe form of malaria that develops in Plasmo...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W1764033598
A portable and wide energy range semiconductor-based neutron spectrometer
Hand-held instruments that can be used to passively detect and identify sources of neutron radiation—either bare or obscured by neutron moderating and/or absorbing material(s)—in real time are of interest in a variety of nuclear non-proliferation and health physics applications. Such an instrument must provide a means ...
[ "Fundamental Constituents of Matter", "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1016/j.electacta.2015.02.165
Interplay between the potential waveform and diffusion layer dynamics determines the time-response of voltammetric detection in microchannels
The diffusion layer is a critical factor affecting the temporal response of electrochemical devices. In this article, we have investigated the effect of the relaxation of the diffusion layer during the potentiodynamic sensing of ferrocenemethanol (FcMeOH) in microchannels and compared these results to amperometry. Firs...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1007/978-1-4939-8769-6_4
13 C Tracer Analysis And Metabolomics In 3D Cultured Cancer Cells
Metabolomics and 13C tracer analysis are state-of-the-art techniques that allow determining the concentration of metabolites and the activity of metabolic pathways, respectively. Three dimensional (3D) cultures of cancer cells constitute an enriched in vitro environment that can be used to assay anchorage-independent g...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1038/ncomms11356
Scalable photonic network architecture based on motional averaging in room temperature gas
Quantum interfaces between photons and atomic ensembles have emerged as powerful tools for quantum technologies. Efficient storage and retrieval of single photons requires long-lived collective atomic states, which is typically achieved with immobilized atoms. Thermal atomic vapours, which present a simple and scalable...
[ "Physical and Analytical Chemical Sciences", "Fundamental Constituents of Matter" ]
W2075666939
Voting-based ensemble-averaging visualization for water mass distribution
The distribution of water masses has become one of the most important topics in recent oceanic research. Water masses flow dynamically and have interannual variability, and hence the distribution can change dramatically even over short time periods and may differ from year to year. In this paper, we use a high-resoluti...
[ "Earth System Science", "Computer Science and Informatics" ]
10.1016/j.chembiol.2018.04.017
PD <inf>n-3 DPA</inf> Pathway Regulates Human Monocyte Differentiation and Macrophage Function
Macrophages are central in orchestrating the clearance of apoptotic cells and cellular debris during inflammation, with the mechanism(s) regulating this process remaining of interest. Herein, we found that the n-3 docosapentaenoic acid-derived protectin (PD n-3 DPA ) biosynthetic pathway regulated the differentiation o...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy", "Cell Biology, Development, Stem Cells and Regeneration" ]
W2059938823
CLIR for Informal Content in Arabic Forum Posts
The field of Cross-Language Information Retrieval (CLIR) addresses the problem of finding documents in some language that are relevant to a question posed in a different language. Retrieving answers to questions written using formal vocabulary from collections of informal documents, as with many types of social media, ...
[ "Computer Science and Informatics" ]
10.1186/s13073-014-0092-4
Approaches for establishing the function of regulatory genetic variants involved in disease
The diversity of regulatory genetic variants and their mechanisms of action reflect the complexity and context-specificity of gene regulation. Regulatory variants are important in human disease and defining such variants and establishing mechanism is crucial to the interpretation of disease-association studies. This re...
[ "Integrative Biology: from Genes and Genomes to Systems", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1093/mnras/stv1918
Broad-band X-ray spectra of anomalous X-ray pulsars and soft γ-ray repeaters: Pulsars in a weak-accretion regime?
We present the results from the analysis of the broad-band X-ray spectra of five anomalous X-ray pulsars (AXPs) and soft γ-ray repeaters (SGRs). We fit their Suzaku and INTEGRAL spectra with models appropriate for the X-ray emission from the accretion flow on to a pulsar. We find that their X-ray spectra can be well de...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
10.1007/s10546-010-9488-x
On the velocity gradient in stably stratified sheared flows. Part 1: Asymptotic analysis and applications
We give a new derivation of the familiar linear relation for the dimensionless velocity gradient in the stably stratified surface layer and provide physical and empirical grounds for its universal applicability in stationary homogeneous turbulence over the whole range of static stabilities from Ri = 0 to very large Ri....
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
W1999884007
Progress in the Total Synthesis of Rocaglamide
The first cyclopenta[b]benzofuran derivative, rocaglamide, from Aglaia elliptifolia , was found to exhibit considerable insecticidal activities and excellent potential as a therapeutic agent candidate in cancer chemotherapy; the genus Aglaia has been subjected to further investigation. Both the structural complexity of...
[ "Synthetic Chemistry and Materials", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
2728115
Next generation security platform to safeguard critical applications and sensitive digital assets
The need to improve data protection has only grown in the past years, fuelled by a large number of high-profile cybercrimes that involved taking over digital assets. One of the most significant data breaches has been the successful theft of 143m customer records from a consumer credit reporting agency Equifax (US)—a cy...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
interreg_1996
KASA - Koiné archeologia: sapiente antichità
Context: The area involved of the project is characterized by a numerous demand of knowledge of their own roots and of a strong sense of identity, demonstrated also by the presence of two University degrees in cultural heritage in Siracusa (Syracuse). At the same time, it is evident that the exploitation is still limi...
[ "The Study of the Human Past", "Studies of Cultures and Arts" ]
W3106341412
Bimodal distribution of the solar wind at 1 AU
Here we aim to separate the two main contributions of slow and fast solar wind that appear at 1 AU. The Bi-Gaussian function is proposed as the probability distribution function of the two main components of the solar wind. The positions of the peaks of every simple Gaussian curve are associated with the typical values...
[ "Universe Sciences", "Fundamental Constituents of Matter" ]
10.1142/9789814449243_0058
The nematic phase of a system of long hard rods
In this talk I consider a two-dimensional lattice model for liquid crystals consisting of long rods interacting via purely hard core interactions, with two allowed orientations defined by the underlying lattice. I report a rigorous proof of the existence of a nematic phase: by this I mean that at intermediate densities...
[ "Condensed Matter Physics", "Mathematics" ]
169841
Use case for european robotics in ophthalmologic micro−surgery
EurEyeCase combines cutting−edge European robotic technology and creates an integrated setup for the very challenging use case of vitreoretinal eye surgery. Nowadays, a selected number of highly−skilled ophthalmologists are treating large numbers of patients that suffer from various types of vitreoretinal eye diseases....
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1038/s41893-019-0262-x
Aridity and reduced soil micronutrient availability in global drylands
Drylands cover more than 40% of the terrestrial surface, and their global extent and socioecological importance will increase in the future due to the forecasted increases in aridity driven by climate change. Despite the essential role of metallic micronutrients in life chemistry and ecosystem functioning, it is virtua...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
W2119880161
Fear extinction in humans: Effects of acquisition–extinction delay and masked stimulus presentations
Fear extinction can be viewed as an inhibitory learning process. This is supported by post-extinction phenomena demonstrating the return of fear, such as reinstatement. Recent work has questioned this account, claiming that extinction initiated immediately after fear acquisition can abolish the return of fear. In the c...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
W1500605161
Effects of aerobic interval and moderate continuous training on erythrocyte rheological property modulated by hypoxic exercise in sedentary men (706.9)
This study investigated how aerobic interval (AIT) and moderate continuous training (MCT) influence hypoxic exercise-mediated erythrocyte aggregability and deformability under various shear conditions in sedentary men. Twenty-four sedentary males were randomized to perform AIT 3-minute intervals at 40% and 80% VO2 peak...
[ "Physiology in Health, Disease and Ageing" ]
US 2014/0034592 W
POLYMERIC CONCRETE ADMIXTURE CONTAINING A NEW CLASS OF SUPERPLASTICIZER POLYMERS
A novel admixture approach to be used in various concrete formulations as a means of modifying and enhancing performance of the concrete. This invention will provide benefits in a variety of ways, including enhanced control over concrete curing times, increased strength and beneficial changes in concrete formulations, ...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1103/PhysRevE.97.023003
Detecting singular weak-dissipation limit for flutter onset in reversible systems
A "flutter machine" is introduced for the investigation of a singular interface between the classical and reversible Hopf bifurcations that is theoretically predicted to be generic in nonconservative reversible systems with vanishing dissipation. In particular, such a singular interface exists for the Pflüger viscoelas...
[ "Physical and Analytical Chemical Sciences", "Mathematics" ]
10.1039/C7CC05011A
Nickel Catalyzed C H Activation Of Purine Bases With Alkyl Halides
C–H alkylations of purine nucleosides were achieved by means of user-friendly nickel catalysis with ample substrate scope and high levels of chemo, site and regio control, which among others enabled the direct fluorescent labeling of purines in terms of late stage diversification.
[ "Synthetic Chemistry and Materials", "Physical and Analytical Chemical Sciences" ]
10.1109/TASLP.2019.2907016
Sound Event Detection In The Dcase 2017 Challenge
Each edition of the challenge on Detection and Classification of Acoustic Scenes and Events DCASE contained several tasks involving sound event detection in different setups. DCASE 2017 presented participants with three such tasks, each having specific datasets and detection requirements: Task 2, in which target sound ...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
GB 9700978 W
SCRAPED SURFACE EVAPORATORS
The present invention relates to scraped surface evaporators (10), and in particular to scrapers (30) for use in scraping the surface of the evaporator (10). Such scraped surface evaporators (10) comprise a refrigerated drum (12), the inner surface of which is scraped by the scraper(s) (30). The scraper is mounted on d...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1039/C4SC01290A
Influence Of Gb3 Glycosphingolipids Differing In Their Fatty Acid Chain On The Phase Behaviour Of Solid Supported Membranes Chemical Syntheses And Impact Of Shiga Toxin Binding
The Shiga toxin B subunit (STxB), which is involved in cell membrane attachment and trafficking of Shiga holotoxin, binds specifically to the glycosphingolipid Gb3. In biological membranes, Gb3 glycosphingolipids differ in their fatty acid composition and there is strong evidence that the fatty acid alters the binding ...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
EP 2021065730 W
CONTROLLER FOR USE WITH A REMOTE DOWNHOLE TOOL
A controller for use with a remote downhole tool is provided. The controller comprises a processor and a transmitter for transmission of control signals to the remote downhole tool. The controller is configured for use at surface or uphole of the remote downhole tool to control transmission of data from the remote down...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1364/OE.23.026639
Laser Ablation And Plasma Etching Based Patterning Of Graphene On Silicon On Insulator Waveguides
We present a new approach to remove monolayer graphene transferred on top of a silicon-on-insulator (SOI) photonic integrated chip. Femtosecond laser ablation is used for the first time to remove graphene from SOI waveguides, whereas oxygen plasma etching through a metal mask is employed to peel off graphene from the g...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1364/OE.23.017355
Laser Assisted Morphing Of Complex Three Dimensional Objects
Morphing refers to the smooth transition from a specific shape into another one, in which the initial and final shapes can be significantly different. A typical illustration is to turn a cube into a sphere by continuous change of shape curvatures. Here, we demonstrate a process of laser-induced morphing, driven by surf...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
10.3389/fimmu.2018.01203
Dysregulation of B cell activity during proliferative kidney disease in rainbow trout
Proliferative kidney disease (PKD) is a widespread disease caused by the endoparasite Tetracapsuloides bryosalmonae (Myxozoa: Malacosporea). Clinical disease, provoked by the proliferation of extrasporogonic parasite stages, is characterized by a chronic kidney pathology with underlying transcriptional changes indicati...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.7554/eLife.17185
Selective protein degradation ensures cellular longevity
A previously unknown pathway can selectively degrade mitochondrial proteins in aged and stressed cells without destroying the organelle itself.
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1007/s40820-019-0314-9
Enhanced Catalytic Activity of Gold@Polydopamine Nanoreactors with Multi-compartment Structure Under NIR Irradiation
Abstract Photothermal conversion (PTC) nanostructures have great potential for applications in many fields, and therefore, they have attracted tremendous attention. However, the construction of a PTC nanoreactor with multi-compartment structure to achieve the combination of unique chemical properties and structural fea...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Condensed Matter Physics" ]
10.1021/acs.langmuir.9b01660
Boundary Lubrication, Hemifusion, and Self-Healing of Binary Saturated and Monounsaturated Phosphatidylcholine Mixtures
A wide range of phosphatidylcholine (PC) lipids with different degrees of unsaturation has been identified in the human synovial fluid and on the cartilage surface. The outstanding lubricity of the articular cartilage surface has been attributed to boundary layers comprising complexes of such lipids, though to date, on...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics", "Materials Engineering" ]
W1975134873
Policy options for mainstreaming forest-based mitigation measures in EU rural development
In the next programming period 2014-2020, climate change will arguably raise as a cross-cutting issue in many – if not most – policies of the EU, including programs and funding related to e.g. energy, transport, research, infrastructure, urban and rural development. Early signs of this attention can be seen in the impl...
[ "Earth System Science", "Human Mobility, Environment, and Space", "Institutions, Governance and Legal Systems" ]
W2054868455
Results of a Community-University Partnership to Reduce Deadly Hazards in Hardwood Floor Finishing
A community-university partnership used community-based participatory research (CBPR) to design, implement, and evaluate a multi-cultural public health campaign to eliminate flammable products and reduce use of products high in volatile organic compounds (VOCs) in hardwood floor finishing in Massachusetts. Leading part...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "The Social World and Its Interactions", "Products and Processes Engineering" ]
interreg_641
Cultural Heritage Operations for the Regeneration of Urban Sites
The city of Bastia in Corsica is the smallest URBACT Lead Partner city in population terms but by no means should this be a judge of the quality of the networking activity. This project which started work in June 2004 with a kick off meeting in Bastia has held a total of 8 seminars and a final conference in November 20...
[ "Human Mobility, Environment, and Space", "The Study of the Human Past" ]
10.1038/nnano.2016.305
Synthesis and characterization of triangulene
Triangulene, the smallest triplet-ground-state polybenzenoid (also known as Clar's hydrocarbon), has been an enigmatic molecule ever since its existence was first hypothesized. Despite containing an even number of carbons (22, in six fused benzene rings), it is not possible to draw Kekulé-style resonant structures for ...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics", "Synthetic Chemistry and Materials" ]
10.1088/1742-6596/506/1/012012
Possible Modification Of The Large Scale Flow Structures By Vortical Structural Interactions
We explore the mechanisms behind vortical structural interactions modifying largescale structures in wall turbulence. The evidence for this in terms of vortex interactions, such as merging and intense vortex strengthening, is found in [4] in ideal flow conditions. Here, these interactions are studied experimentally and...
[ "Condensed Matter Physics", "Products and Processes Engineering" ]
10.1080/2153599X.2016.1236033
After God S Image Prayer Leads People With Positive God Beliefs To Read Less Hostility In Others Eyes
Across cultures and historical periods, people have attributed human traits to the divine. Because of the similarity between people’s mental representations of God and their mental representations . . .
[ "The Human Mind and Its Complexity" ]
10.1007/978-3-319-93417-4_12
Tweetskb A Public And Large Scale Rdf Corpus Of Annotated Tweets
Publicly available social media archives facilitate research in a variety of fields, such as data science, sociology or the digital humanities, where Twitter has emerged as one of the most prominent sources. However, obtaining, archiving and annotating large amounts of tweets is costly. In this paper, we describe Tweet...
[ "Computer Science and Informatics", "The Social World and Its Interactions" ]
10.1002/anie.201611432
“Molecular Activity Painting”: Switch-like, Light-Controlled Perturbations inside Living Cells
Acute subcellular protein targeting is a powerful tool to study biological networks. However, signaling at the plasma membrane is highly dynamic, making it difficult to study in space and time. In particular, sustained local control of molecular function is challenging owing to the lateral diffusion of plasma membrane ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Physical and Analytical Chemical Sciences" ]
10.1007/978-3-319-66254-1_8
Anti Poverty Programs And Vote Buying Strategies Lessons From Northeast Brazil
In a context where personal relations play a central role in structuring political life, to what extent should a researcher differentiate “normal” from “deviant” political behavior? This chapter addresses this question from a socio-anthropological point of view, analyzing the use of anti-poverty programs for vote-buyin...
[ "Studies of Cultures and Arts", "The Social World and Its Interactions", "Institutions, Governance and Legal Systems" ]
185357
Feasibility study: a first-of-its-kind software-defined virtual reality camera
Virtual reality (VR) is a long awaited technology which can be named as #1 media to influence the way how modern society will consume video content in the future. Up to 400 million consumers will become the audience for VR content until 2020. However, there is a grass-root problem with VR content generation as there ...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
interreg_540
CA.V.E.: CAVES VIRTUAL ENVIRONMENT
The overall project aims to further enhance and highlight the specific natural, geological, historical and cultural identity of the caves, using innovative technological applications based on virtual reality. The main expected outputs include: • Web-based virtual reality applications (the geological birth and evolution...
[ "Computer Science and Informatics", "Earth System Science", "The Study of the Human Past" ]
295362
Bi-literacy: Learning to read in L1 and in L2
Learning to read is probably one of the most exciting discoveries in our life. Using a longitudinal approach, the research proposed examines how the human brain responds to two major challenges: (a) the instantiation a complex cognitive function for which there is no genetic blueprint (learning to read in a first langu...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1182/blood-2018-07-866830
The HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy
Abstract Antileukemia immunity plays an important role in disease control and maintenance of tyrosine kinase inhibitor (TKI)-free remission in chronic myeloid leukemia (CML). Thus, antigen-specific immunotherapy holds promise for strengthening immune control in CML but requires the identification of CML-associated targ...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
864672
Evolutionary Consequences of Arrested Genomic Conflict in Asexual Species
Genomic conflicts are major drivers of evolutionary innovation and play an increasingly recognized role in human disease. Intra-genomic conflicts arise because self-promoting elements such as driving centromeres or transposable elements (TEs) can spread in a population without increasing the fitness of their carriers. ...
[ "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1016/j.immuni.2015.05.018
GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c<sup>+</sup>MHCII<sup>+</sup> Macrophages and Dendritic Cells
Dendritic cells (DCs) are key players in the immune system. Much of their biology has been elucidated via culture systems in which hematopoietic precursors differentiate into DCs under the aegis of cytokines. A widely used protocol involves the culture of murine bone marrow (BM) cells with granulocyte-macrophage colony...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1063/1.4961307
Spider Web Inspired Acoustic Metamaterials
Spider silk is a remarkable example of bio-material with superior mechanical characteristics. Its multilevel structural organization of dragline and viscid silk leads to unusual and tunable properties, extensively studied from a quasi-static point of view. In this study, inspired by the Nephila spider orb web architect...
[ "Condensed Matter Physics", "Materials Engineering" ]
743032
Dynamics of Probed, Pulsed, Quenched and Driven Integrable Quantum Systems
This proposal intends to develop and apply a new-generation theoretical toolbox for understanding the rich dynamics of strongly-interacting many-body quantum sytems subjected to destabilizing manipulations bringing them very far from equilibrium. In atomic systems, condensed matter and nanophysics settings, quantum m...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
725701
Directed crop breeding using jumping genes
The rapidly changing climate puts commonly used crop plants under strong pressure. It is therefore essential to develop novel breeding technologies to rapidly enhance crops to better withstand newly emerging stresses. Interestingly, a clear link between transposable elements (TEs), crop improvement and varietal diversi...
[ "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering" ]
W1992294822
Update of hematopoietic cell transplantation for sickle cell disease
Hematopoietic cell transplantation (HCT) is a curative therapy for sickle cell disease (SCD) that is utilized very rarely because of limited allogeneic donor availability, limited healthcare resources needed to expand the treatment to regions in the world where most affected individuals reside, and by a view among SCD ...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1002/cbic.201402603
Insect-specific production of new GameXPeptides in Photorhabdus luminescens TTO1, widespread natural products in entomopathogenic bacteria
Discovery of new natural products by heterologous expression reaches its limits, especially when specific building blocks are missing in the heterologous host or the production medium. Here, we describe the insect-specific production of the new GameXPeptides E-H (5-8) from Photorhabdus luminescens TTO1, which can be pr...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering" ]