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W1613806312
Gold-Polymer Nanocomposites for Bioimaging and Biosensing
The sections in this article are Introduction Fabrication of Gold Nanocomposites General Aspects “Grafting-From” Modifications “Grafting-To” Modifications Post-Modification Imaging and Labeling with Gold Nanocomposites Optical Imaging Magnetic Resonance Imaging, X-Ray Imaging, and Surface-Enhanced Rama...
[ "Materials Engineering", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1142/S1230161215500018
An Improvement On The Delsarte Type Lp Bound With Application To Mubs
The linear programming (LP) bound of Delsarte can be applied to several problems in various branches of mathematics. We describe a general Fourier analytic method to get a slight improvement on this bound. We then apply our method to the problem of mutually unbiased bases (MUBs) to prove that the Fourier family $F(a,b)...
[ "Mathematics" ]
W2390526642
Prediction of the Number of Medals in International General Games: With Beijing Olympic Games as an Example
Based on theories of econometrics,population,GDP per capita,home advantage,social system,achievements in the previous Olympic Games,this paper established a preliminary model with multiple non-linear regression analysis.Considering the discrepancy in competitive sports strength between countries,the authors divided com...
[ "Individuals, Markets and Organisations", "Computer Science and Informatics" ]
10.1021/la500408j
Neither Lippmann nor young: Enabling electrowetting modeling on structured dielectric surfaces
Aiming to illuminate mechanisms of wetting transitions on geometrically patterned surfaces induced by the electrowetting phenomenon, we present a novel modeling approach that goes beyond the limitations of the Lippmann equation and is even relieved from the implementation of the Young contact angle boundary condition. ...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
10.1109/TNNLS.2015.2465178
Robust Low Rank Tensor Recovery With Regularized Redescending M Estimator
This paper addresses the robust low-rank tensor recovery problems. Tensor recovery aims at reconstructing a low-rank tensor from some linear measurements, which finds applications in image processing, pattern recognition, multitask learning, and so on. In real-world applications, data might be contaminated by sparse gr...
[ "Mathematics", "Computer Science and Informatics" ]
W2112625081
Unexpected 1,2-Migration in Metallasilabenzenes: Theoretical Evidence for Reluctance of Silicon to Participate in π Bonding
Density functional theory (DFT) calculations were carried out to investigate the 1,2-migration in metallasilabenzenes. The results suggested that the chloride migration of metallabenzenes is unfavorable due to the loss of aromaticity in the nonaromatic analogues. In sharp contrast, such a migration in metallasilabenzen...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
interreg_2802
The third step in protecting the territory from natural risks: participatory evolution
This project is an evolution of what was carried out in the 2007-2013 Planning with the PROTERINA-2, RESMAR and PROTERINA-C projects. It aims to improve the capacity of institutions to prevent and jointly manage the risk of floods. The general objective of the project is to strengthen the ability of institutions and co...
[ "Earth System Science", "Human Mobility, Environment, and Space", "Institutions, Governance and Legal Systems" ]
10.4161/auto.26841
Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors
Removal of ubiquitinated targets by autophagosomes can be mediated by receptor molecules, like SQSTM1, in a mechanism referred to as selective autophagy. While cytoplasmic protein aggregates, mitochondria, and bacteria are the best-known targets of selective autophagy, their role in the turnover of membrane receptors i...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1038/nn.4194
DNA methylation changes in plasticity genes accompany the formation and maintenance of memory
The ability to form memories is a prerequisite for an organism's behavioral adaptation to environmental changes. At the molecular level, the acquisition and maintenance of memory requires changes in chromatin modifications. In an effort to unravel the epigenetic network underlying both short- and long-term memory, we e...
[ "Neuroscience and Disorders of the Nervous System", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1515/jgth-2014-0043
Infinitely-ended hyperbolic groups with homeomorphic Gromov boundaries
We show that the Gromov boundary of the free product of two infinite hyperbolic groups is uniquely determined up to homeomorphism by the homeomorphism types of the boundaries of its factors. We generalize this result to graphs of hyperbolic groups over finite subgroups. Finally, we give a necessary and sufficient condi...
[ "Mathematics" ]
282330
Sequence based strategies to identify genetic variation associated with mental retardation and schizophrenia
Mental retardation (MR) and schizophrenia (SCZ) are disorders of the brain that affect 2-3% and 1% of the population, respectively. Both disorders are considered to be highly heritable, but exhibit heterogeneous genetic etiology. Recent genetic studies have led to discoveries that the same variants that can give rise t...
[ "Neuroscience and Disorders of the Nervous System", "Integrative Biology: from Genes and Genomes to Systems", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1111/jcpp.12171
Genetic and environmental influences on adolescent attachment
Background Twin studies consistently point to limited genetic influence on attachment security in the infancy period, but no study has examined whether this remains the case in later development. This study presents the findings from a twin study examining the relative importance of genetic and environmental influences...
[ "Integrative Biology: from Genes and Genomes to Systems", "The Human Mind and Its Complexity" ]
US 2007/0083120 W
INHIBITORS OF HEPATITIS C VIRUS
Macrocyclic peptides are disclosed having the general formula: (I) wherein R<SUB>3</SUB>, R'<SUB>3, </SUB>R<SUB>4</SUB>, R<SUB>6</SUB>, R', X, Q and W are described. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy" ]
10.1051/0004-6361/201834933
Novel Method For Component Separation Of Extended Sources In X Ray Astronomy
In high-energy astronomy, spectro-imaging instruments such as X-ray detectors allow investigation of the spatial and spectral properties of extended sources including galaxy clusters, galaxies, diffuse interstellar medium, supernova remnants and pulsar wind nebulae. In these sources, each physical component possesses a...
[ "Universe Sciences", "Computer Science and Informatics" ]
US 54812009 A
Prosthesis with Moveable Fenestration
An endoluminal prosthesis with a moveable fenestration including a tubular graft body having a proximal end, a distal end, a surface plane at least one fenestration having a perimeter disposed in a sidewall of the tubular body between the proximal end and the distal end, a first biocompatible graft material, and a seco...
[ "Products and Processes Engineering", "Materials Engineering" ]
W1987733793
Emergency preparedness and response for transport: elements to consider when developing emergency response plans
The safety record of radioactive material shipments is impressive. In over 50 years, there has never been a transport event that has caused significant radiological damage to health, property and the environment. However, safety cannot be taken for granted. Emergency preparedness and response are important elements to ...
[ "Products and Processes Engineering" ]
10.1007/s10677-013-9437-0
Moral Contextualism and the Problem of Triviality
Moral contextualism is the view that claims like 'A ought to X' are implicitly relative to some (contextually variable) standard. This leads to a problem: what are fundamental moral claims like 'You ought to maximize happiness' relative to? If this claim is relative to a utilitarian standard, then its truth conditions ...
[ "Texts and Concepts" ]
10.23919/FPL.2017.8056797
Transparent Memory Encryption And Authentication
Security features of modern (SoC) FPGAs permit to protect the confidentiality of hard- and software IP when the devices are powered off as well as to validate the authenticity of IP when being loaded at startup. However, these approaches are insufficient since attackers with physical access can also perform attacks dur...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1016/j.coviro.2011.09.012
RNA virus population diversity: Implications for inter-species transmission
RNA viruses are notorious for rapidly generating genetically diverse populations during a single replication cycle, and the implications of this mutant population, often referred to as quasispecies, can be vast. Previous studies have linked RNA virus genetic variability to changes in viral pathogenesis, the ability to ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Immunity, Infection and Immunotherapy" ]
10.1371/journal.pone.0145265
Schooling, local knowledge and working memory: A study among three contemporary hunter-gatherer societies
Researchers have analysed whether school and local knowledge complement or substitute each other, but have paid less attention to whether those two learning models use different cognitive strategies. In this study, we use data collected among three contemporary huntergatherer societies with relatively low levels of exp...
[ "Environmental Biology, Ecology and Evolution", "The Human Mind and Its Complexity" ]
10.1162/jocn_a_01592
Sequence Memory in the Hippocampal–Entorhinal Region
Episodic memories are constructed from sequences of events. When recalling such a memory, we not only recall individual events, but we also retrieve information about how the sequence of events unfolded. Here, we focus on the role of the hippocampal–entorhinal region in processing and remembering sequences of events, w...
[ "Neuroscience and Disorders of the Nervous System" ]
185248
Novel closed-cage system for high-value marine aquaculture
The global demand for seafood is in a period of exceptional growth, making up 16% of all consumed animal protein, or 119m tonnes annually, expected to increase to 152m tonnes by 2030. Wild stocks, are near or beyond their sustainable limit, resulting in an annual production shortfall of ca. 30m tonnes by 2030. Farmed s...
[ "Products and Processes Engineering", "Environmental Biology, Ecology and Evolution" ]
10.1038/s41570-016-0005
Generation, manipulation and characterization of molecules by atomic force microscopy
Using atomic manipulation, one can dissociate, form and rearrange bonds, as well as alter the conformation or charge state of molecules. The molecular structures of reactants, intermediates and products are revealed at unprecedented resolution by using atomic force microscopy (AFM) and a suitably functionalized tip. Ou...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
Q2703115
Support for the financing of working capital following the deterioration of the situation of the company as a result of the COVID-19 pandemic
The project aims to support the continuation of the business of a company that is in a situation of sudden shortage due to the COVID-19 outbreak. The applicant applies for grants to finance working capital and cover the running costs for a period of three months.
[ "Individuals, Markets and Organisations" ]
10.1007/s00220-013-1752-8
Universal Finite Size Corrections and the Central Charge in Non-solvable Ising Models
We investigate a non-solvable two-dimensional ferromagnetic Ising model with nearest neighbor plus weak finite range interactions of strength λ. We rigorously establish one of the predictions of Conformal Field Theory (CFT), namely the fact that at the critical temperature the finite size corrections to the free energy...
[ "Condensed Matter Physics", "Mathematics" ]
W1983639150
A study on surface slant encoding in V1
Inter-ocular differences in spatial frequency occur during binocular viewing of a surface slanted in depth. Cortical cells with inter-ocular differences in preferred spatial frequency (dif-frequency cells) are expected to detect surfaces slanted in depth or vertical surface slant. Using our reaction-diffusion model, we...
[ "Neuroscience and Disorders of the Nervous System", "Computer Science and Informatics" ]
10.1002/mrd.23341
RS-1 enhances CRISPR-mediated targeted knock-in in bovine embryos
Targeted knock-in (KI) can be achieved in embryos by clustered regularly interspaced short palindromic repeats (CRISPR)-assisted homology directed repair (HDR). However, HDR efficiency is constrained by the competition of nonhomologous end joining. The objective of this study was to explore whether CRISPR-assisted targ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1002/cssc.201200766
Novel process windows for enabling, accelerating, and uplifting flow chemistry
Novel Process Windows make use of process conditions that are far from conventional practices. This involves the use of high temperatures, high pressures, high concentrations (solvent-free), new chemical transformations, explosive conditions, and process simplification and integration to boost synthetic chemistry on bo...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Products and Processes Engineering" ]
313552
The Architecture of Consciousness
The nature of consciousness is one of the great unsolved mysteries of science. Although the global research effort dedicated to explaining how consciousness arises from neural and cognitive activity is now more than two decades old, as yet there is no widely accepted theory of consciousness. One reason for why no adequ...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1016/j.molcel.2011.07.027
Life Span Extension and H2O2 Resistance Elicited by Caloric Restriction Require the Peroxiredoxin Tsa1 in Saccharomyces cerevisiae
Caloric restriction (CR) extends the life span of organisms ranging from yeast to primates. Here, we show that the thiol-dependent peroxiredoxin Tsa1 and its partner sulfiredoxin, Srx1, are required for CR to extend the replicative life span of yeast cells. Tsa1 becomes hyperoxidized/inactive during aging, and CR mitig...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
683029
Ultimate Angular Resolution Astrophysics with kernel-phase and full-aperture interferometry
Astronomy requires large telescopes to improve the sensitivity and the angular resolution of its observations. Of these qualities, angular resolution is the most difficult to maintain in the optical and near-infrared, since the atmosphere reduces it to that of a 10 cm aperture, regardless of the telescope size. On the ...
[ "Universe Sciences", "Systems and Communication Engineering" ]
10.1126/science.1204656
A <sup>15</sup>N-poor isotopic composition for the solar system as shown by genesis solar wind samples
The Genesis mission sampled solar wind ions to document the elemental and isotopic compositions of the Sun and, by inference, of the protosolar nebula. Nitrogen was a key target element because the extent and origin of its isotopic variations in solar system materials remain unknown. Isotopic analysis of a Genesis Sola...
[ "Physical and Analytical Chemical Sciences", "Universe Sciences" ]
10.1016/j.actbio.2015.07.034
Control of crosslinking for tailoring collagen-based scaffolds stability and mechanics
We provide evidence to show that the standard reactant concentrations used in tissue engineering to cross-link collagen-based scaffolds are up to 100 times higher than required for mechanical integrity in service, and stability against degradation in an aqueous environment. We demonstrate this with a detailed and syste...
[ "Materials Engineering", "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1007/978-1-4614-9414-0_2
Investigating Recursion Within A Domain Specific Framework
Recursion is a cognitive ability that has captured the interest of many theorists, due to its possible role in the development of specifically human behaviours, such as language, music and architecture. However, empirical investigation of recursion has been hindered by the lack of a consistent and consensual framework....
[ "The Human Mind and Its Complexity" ]
W1607774830
Embracing leadership: a multi-faceted model of leader identity development
Purpose – Leadership development has been replete with a skill-based focus. However, learning and development can be constrained by the deeper level, hidden self-knowledge that influences how people process information and construct meaning. The purpose of this paper is to answer the question of how people construct an...
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity" ]
10.1080/17470218.2015.1136656
Learning Faces From Variability
Research on face learning has tended to use sets of images that vary systematically on dimensions such as pose and illumination. In contrast, we have proposed that exposure to naturally varying ima. . .
[ "Computer Science and Informatics" ]
10.30965/25890433-04801004
Frieden schließen auf Konzilien? Zwei Beispiele aus dem vierten Jahrhundert
The essay examines two exemplary attempts to ‘make peace’ between rivaling theological factions in the middle of the fourth century. The negotiations conducted in Alexandria in 362, of which the Tomus ad Antiochenos provides a distillation, confirm the importance of exploring theological concepts and terminological pre...
[ "The Study of the Human Past", "Texts and Concepts" ]
10.1109/TRO.2013.2289018
Data Driven Grasp Synthesis A Survey
We review the work on data-driven grasp synthesis and the methodologies for sampling and ranking candidate grasps. We divide the approaches into three groups based on whether they synthesize grasps for known, familiar or unknown objects. This structure allows us to identify common object representations and perceptual ...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
W4223950446
Problematic donation procedures vs. futuristic research and treatment applications: A dichotomous social representation of stem cells in Italy
Currently, stem cells (SC) are one of the most studied issues of medical research as well as a widespread, complex, socially and ethically relevant issue. The general aim of the present study is to explore how social representations (SR) of SC is different for people more or less willing to donate SC, also comparing bo...
[ "Cell Biology, Development, Stem Cells and Regeneration", "The Social World and Its Interactions", "The Human Mind and Its Complexity" ]
W1822914510
Classification based on multi-classifier of SVM fusion for steel strip surface defects
Aiming at the existing problems in pattern recognition of surface defect images of steel strips, a new classification and recognition method based on multi-classifier of support vector machine (SVM) fusion is proposed to solve them. Firstly extracted the Hu invariant moment features, gray features and texture features,...
[ "Computer Science and Informatics", "Materials Engineering", "Products and Processes Engineering" ]
10.5194/cp-15-1427-2019
Impact of different estimations of the background-error covariance matrix on climate reconstructions based on data assimilation
Abstract. Data assimilation has been adapted in paleoclimatology to reconstruct past climate states. A key component of some assimilation systems is the background-error covariance matrix, which controls how the information from observations spreads into the model space. In ensemble-based approaches, the background-err...
[ "Earth System Science", "Computer Science and Informatics", "Mathematics" ]
W2051674579
Foreword: Eukaryotic DNA replication: is time of the essence?
The visionary studies of Watson and Crick (1953) first proposed a structure for DNA to suggest a ‘possible copying mechanism for the genetic material’. Ever since, cell biologists have marvelled at the mysteries by which this most fundamental process of cell proliferation is controlled. The importance of mechanisms tha...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
184530
Advanced design of very high power density piston engine and thermal management challenges for aircraft application
Danielson Engineering is an SME based in Magny Cours (France), SRC certified (Société de Recherche sous Contrat), specialising in the design, the optimisation, the manufacturing and experimental development of innovative engines for automotive and aeronautical applications (http://www.danielson-eng.fr/en/). Danielson ...
[ "Products and Processes Engineering", "Materials Engineering", "Systems and Communication Engineering" ]
W2901317293
Adding a New Category of “Individual vs System” to the Economics
After the industrial revolution, the long-term effort of resolving the threat of resource scarcity was accomplished globally in the 1950s. However, the threat of environmental destruction was, and still is, accumulating along the way. As mainstream economics is the main culprit of environmental destruction, it cann...
[ "Individuals, Markets and Organisations" ]
10.1109/WACV.2017.142
Switching Linear Inverse Regression Model For Tracking Head Pose
We propose to estimate the head-pose angles (pitch, yaw, and roll) by simultaneously predicting the pose parameters from observed high-dimensional feature vectors, and tracking these parameters over time. This is achieved by embedding a Gaussian mixture of linear inverse-regression model into a dynamic Bayesian model. ...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1109/ISVLSI.2015.7
Hybrid Stt Cmos Design Of An Interrupt Based Instant On Off Mechanism For Low Power Soc
This paper describes the design and the evaluation of a low-power System-on-Chip (SoC) in an advanced hybrid 40nm magnetic/CMOS technology node. Without external memory interface, the processor of the SoC benefits from a privileged access to the embedded NVM (Non-Volatile Memory), providing means for internal data stor...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
773067
The Insect cochlea: a non-invasive path towards enhanced sound detectors
There is a critical need for high-resolution acoustic sensors for numerous applications in engineering/medicine. The human cochlea has been a source of inspiration for acoustic sensors due its improved sensitivity, higher frequency range, and sharp frequency discrimination. Current methods for measuring cochlear mecha...
[ "Condensed Matter Physics", "Systems and Communication Engineering", "Materials Engineering" ]
10.1007/s00125-019-4919-9
Paternal impact on the life course development of obesity and type 2 diabetes in the offspring
The aetiologies of obesity and type 2 diabetes are incredibly complex, but the potential role of paternal influences remains relatively understudied. A better understanding of paternal influences on offspring risk of obesity and type 2 diabetes could have profound implications for public health, clinical practice and s...
[ "Physiology in Health, Disease and Ageing", "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1017/S1062798714000532
Why Antimatter Matters
Almost ten years after the first production of cold antimatter at CERN, the confinement of antihydrogen has recently been achieved for the first time. Several experiments installed at the Antiproton Decelerator intend to test the symmetry between matter and antimatter by means of trapped anti-atoms. In addition, in the...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
10.1038/s42003-019-0426-2
15-deoxy-Δ<sup>12,14</sup>-Prostaglandin J<inf>2</inf> inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism
Human soluble epoxide hydrolase (hsEH) is an enzyme responsible for the inactivation of bioactive epoxy fatty acids, and its inhibition is emerging as a promising therapeutical strategy to target hypertension, cardiovascular disease, pain and insulin sensitivity. Here, we uncover the molecular bases of hsEH inhibition ...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
GB 2009050586 W
WATER HEATING APPARATUS
Disclosed is a solar water heating apparatus comprising a central tank and one or more outer layerswherein at least part of the exterior of the outermost layer is adapted to be exposed to the sun. The outer layers also formwater pathways such that, when the tank is substantially filled with water, said water is able to...
[ "Products and Processes Engineering", "Materials Engineering" ]
US 2009/0040444 W
REINFORCED MEDICAL DEVICE
An apparatus and method for a medical implant having a reinforced medical implant body. In an embodiment of the invention, an apparatus includes a sheath, a conductive element, a distal electrode and a length limiting element. The conductive element has a proximal end and a distal end. The distal electrode can be coupl...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1088/1751-8113/44/45/454004
Generic Multiloop Methods And Application To Cal N 4 Super Yang Mills
We review some recent additions to the tool-chest of techniques for finding compact integrand representations of multiloop gauge-theory amplitudes—including non-planar contributions—applicable for super-Yang–Mills in four and higher dimensions, as well as for theories with less supersymmetry. We discuss a general organ...
[ "Fundamental Constituents of Matter", "Mathematics" ]
10.1107/S2053230X15007566
Structure Of The Catalytic Domain Of Mre11 From Chaetomium Thermophilum
Together with the Rad50 ATPase, the Mre11 nuclease forms an evolutionarily conserved protein complex that plays a central role in the repair of DNA double-strand breaks (DSBs). Mre11-Rad50 detects and processes DNA ends, and has functions in the tethering as well as the signalling of DSBs. The Mre11 dimer can bind one ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2472758444
Understanding Older Adult Use of Data Visualizations as a Resource for Maintaining Health and Wellness
To better understand how older adults use health visualizations and the potential barriers that impact utility, we conducted semistructured interviews with 21 older adults. Within these sessions, we presented participants with two interactive visualizations for exploration. Through an affinity mapping exercise, we extr...
[ "Computer Science and Informatics", "The Human Mind and Its Complexity", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1002/chem.201705692
Infrared Multiphoton Dissociation Spectroscopy with Free-Electron Lasers: On the Road from Small Molecules to Biomolecules
Infrared multiphoton dissociation (IRMPD) spectroscopy is commonly used to determine the structure of isolated, mass-selected ions in the gas phase. This method has been widely used since it became available at free-electron laser (FEL) user facilities. Thus, in this Minireview, we examine the use of IRMPD/FEL spectros...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
EP 2022085540 W
METHOD FOR PRODUCING A DECORATIVE PRINT, METHOD FOR IMPRINTING A WORKPIECE, AND SYSTEM
The invention relates to a method for producing a decorative print, to a method for imprinting an (in particular panel-like) workpiece, and to a machine for imprinting an (in particular panel-like) workpiece. Methods of this type and a system of this type are used in particular in the sphere of the wood-processing indu...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1038/s41593-019-0479-z
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity
Mitochondria vary in morphology and function in different tissues; however, little is known about their molecular diversity among cell types. Here we engineered MitoTag mice, which express a Cre recombinase-dependent green fluorescent protein targeted to the outer mitochondrial membrane, and developed an isolation appr...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2090613515
Commentary: new development goals must focus on social determinants of health
Although the millennium development goals (MDGs) addressed some of the starkest manifestations of the contemporary global health crisis, they failed to confront the underlying structures that maintain the crisis, including globalisation. In reflecting on the post-2015 development agenda,1 we need to challenge some key ...
[ "The Social World and Its Interactions", "Individuals, Markets and Organisations", "Human Mobility, Environment, and Space" ]
171862
Reducing empiricism in luminescence geochronology: understanding the origins of luminescence from individual sand grains
Sediments preserve a history of the evolution of the Earth’s surface and its response to a changing climate – a history that can only be read reliably if we know the age of the sediments. Luminescence dating is widely used in quaternary geology and archaeology, and is applicable to almost all sediments from the last 0....
[ "Earth System Science", "Physical and Analytical Chemical Sciences", "Fundamental Constituents of Matter" ]
10.3390/cells9061390
A Proximity Mapping Journey into the Biology of the Mammalian Centrosome/Cilium Complex
The mammalian centrosome/cilium complex is composed of the centrosome, the primary cilium and the centriolar satellites, which together regulate cell polarity, signaling, proliferation and motility in cells and thereby development and homeostasis in organisms. Accordingly, deregulation of its structure and functions is...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1038/s41589-019-0443-y
A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells
Protein interactions guide most cellular processes. Orthogonal hetero-specific protein–protein interaction domains may facilitate better control of engineered biological systems. Here, we report a tunable de novo designed set of orthogonal coiled-coil (CC) peptide heterodimers (called the NICP set) and its application ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering" ]
10.1162/JEEA.2009.7.1.206
Herd Behavior In Financial Markets An Experiment With Financial Market Professionals
We study herd behavior in a laboratory financial market with financial market professionals. An important novelty of the experimental design is the use of a strategy-like method. This allows us to detect herd behavior directly by observing subjects' decisions for all realizations of their private signal. In the paper, ...
[ "Individuals, Markets and Organisations" ]
10.1016/j.jasrep.2019.102077
Livestock production, politics and trade: A glimpse from Iron Age and Roman Languedoc
Mobility is crucial in animal husbandry to overcome scarcity of food and the related over-grazing of pastures. It is also essential to reduce the inbreeding rate of animal populations, which is known to have a negative impact on fertility and productivity. Complex societies with a strong territorial component developed...
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]
10.1364/OE.25.029687
Optical Peregrine Rogue Waves Of Self Induced Transparency In A Resonant Erbium Doped Fiber
The resonant interaction of an optical field with two-level doping ions in a cryogenic optical fiber is investigated within the framework of nonlinear Schrodinger and Maxwell-Bloch equations. We present explicit fundamental rational rogue wave solutions in the context of self-induced transparency for the coupled optica...
[ "Fundamental Constituents of Matter", "Systems and Communication Engineering", "Mathematics" ]
W2487059353
A Networks Approach to Modeling Enzymatic Reactions
Modeling enzymatic reactions is a demanding task due to the complexity of the system, the many degrees of freedom involved and the complex, chemical, and conformational transitions associated with the reaction. Consequently, enzymatic reactions are not determined by precisely one reaction pathway. Hence, it is benefici...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Computer Science and Informatics" ]
203481
Understanding the structure and stability of heavy and superheavy elements
The aim of the project is to further our understanding of the structure and stability of atomic nuclei at the extreme upper end of the chart of the nuclides. One of the major goals of contemporary Nuclear Physics experiments is to locate and chart the fabled superheavy element ""Island of Stability"". Experiments which...
[ "Fundamental Constituents of Matter" ]
10.1007/978-3-030-01845-0_140
Depression Modulates Attentional Processing After Stroke
Depression is a common sequela after stroke and has severe implications on a patient’s life. Post-stroke depression has been linked to cognitive impairment, but the mechanisms that lead to this deficit are not well understood. We tested 18 chronic stroke patients with depression in a psychophysical task to evaluate the...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
W2122393640
A New Additive Homomorphic Encryption based on the co-ACD Problem
We propose an efficient additive homomorphic encryption scheme. In our scheme, an encryption of a message is simply its noisy modular reduction by several different moduli. The security of our scheme relies on the hardness of a new problem, the co-Approximate Common Divisor problem. We analyze its hardness by applying ...
[ "Computer Science and Informatics", "Mathematics" ]
281854
Hypothalamic Lipotoxicity and Endoplasmic Reticulum Stress: a New Pathophysiological Mechanism of Obesity
It is well established that metabolically relevant organs such as adipose tissue, pancreatic beta cells, liver and skeletal muscle develop endoplasmic reticulum (ER) stress under conditions of obesity induced lipotoxicity. Here, the applicant will investigate if/how the hypothalamus is affected by lipotoxicity and ER s...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
883578
Intelligent prosthesis system
Phantom pain and the risk of falling are the two major unsolved problems of leg and foot amputees. The Austrian company Saphenus Medical Technology is developing a sensory feedback system (IPS) that solves these two problems. The novelty of IPS is the «feeling prosthesis» for the leg: The authentic capturing of the gai...
[ "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases", "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1137/140998846
Pricing On Paths A Ptas For The Highway Problem
In the highway problem, we are given an $n$-edge path graph (the highway), and a set of paths (the drivers), each one with its own budget. For a given assignment of edge weights (the tolls), the highway owner collects from each driver the weight of the associated path, when it does not exceed the budget of the driver, ...
[ "Computer Science and Informatics" ]
10.1038/ncomms6639
Enrichment of CD56<sup>dim</sup>KIR+CD57+ highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients
An important checkpoint in the progression of melanoma is the metastasis to lymph nodes. Here, to investigate the role of lymph node NK cells in disease progression, we analyze frequency, phenotype and functions of NK cells from tumour-infiltrated (TILN) and tumour-free ipsilateral lymph nodes (TFLN) of the same patien...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1111/ele.13196
Pyramids and cascades: a synthesis of food chain functioning and stability
Food chain theory is one of the cornerstones of ecology, providing many of its basic predictions, such as biomass pyramids, trophic cascades and predator–prey oscillations. Yet, ninety years into this theory, the conditions under which these patterns may occur and persist in nature remain subject to debate. Rather than...
[ "Environmental Biology, Ecology and Evolution" ]
W2119217901
Remanufacturing Technology Innovation for Second-Hand Computer
The volume tendency of in-use and second-hand computers in China were analyzed, the emerging danger of second-hand computers by incorrect treatment was summarized, the integration disposal technologies based on remanufacture and reuse technology aiming at monitors, electronic devices, metals, plastics materials, and ov...
[ "Products and Processes Engineering", "Environmental Biology, Ecology and Evolution" ]
10.1103/PhysRevX.6.041015
Binary Black Hole Mergers in the First Advanced LIGO Observing Run
The first observational run of the Advanced LIGO detectors, from September 12, 2015 to January 19, 2016, saw the first detections of gravitational waves from binary black hole mergers. In this paper, we present full results from a search for binary black hole merger signals with total masses up to 100M· and detailed im...
[ "Universe Sciences", "Fundamental Constituents of Matter" ]
185477
Sharing researchers’ passion for engagement and responsibility
Researchers love to engage with nature, society, with future and ultimately with all the complex challenges that will allow them to contribute to a better world. Researchers also love to engage with other people to make the quest they’re involved in a collective endeavour. All this make researchers persons passionate f...
[ "The Social World and Its Interactions", "Human Mobility, Environment, and Space" ]
W2096630086
Size-fractionated PM10 monitoring in relation to the contribution of endotoxins in different polluted areas
Abstract Particulate pollution is an environmental concern that is widespread and difficult to resolve. Recently various regulatory improvements around the world have been agreed upon to tackle this problem, especially as related to the fine fraction of particulates, which more closely correlates to human health effect...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
EP 2008003836 W
METHOD FOR PRODUCING A WOVEN FABRIC AND WOVEN FABRIC PRODUCED THEREBY
The invention relates to a method for producing a woven fabric (8, 9), the woven fabric (8, 9) comprising at least one monofil or monofil-like weft thread made of highly shrinkable material and warp threads made of low-shrinkage material, characterized in that at least one multifil weft thread (18, 19) running in the s...
[ "Products and Processes Engineering", "Materials Engineering" ]
174859
Mechanisms of auxin-dependent signaling in the endoplasmic reticulum
The phytohormone auxin has profound importance for plant development. The extracellular AUXIN BINDING PROTEIN1 (ABP1) and the nuclear AUXIN F-BOX PROTEINs (TIR1/AFBs) auxin receptors perceive fast, non-genomic and slow, genomic auxin responses, respectively. Despite the fact that ABP1 mainly localizes to the endoplasmi...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
W2059904277
Preliminary radiological safety assessment for decommissioning of thoria dissolver of the 233U pilot plant, Trombay
The thoria dissolver, used for separation of (233)U from reactor-irradiated thorium metal and thorium oxide rods, is no longer operational. It was decided to carry out assessment of the radiological status of the dissolver cell for planning of the future decommissioning/dismantling operations. The dissolver interiors a...
[ "Physical and Analytical Chemical Sciences", "Products and Processes Engineering" ]
10.11141/ia.42.5
Lithic residue survival and characterisation at star carr: A burial experiment
A modern burial experiment was devised to test microscopic residue survival in acidic peat and slightly acidic clay soils at the Early Mesolithic site of Star Carr (North Yorkshire, UK), and at nearby control location. The experiment addresses concerns regarding the applicability of residue analysis in varied burial en...
[ "The Study of the Human Past", "Earth System Science" ]
10.3389/fphys.2019.00891
CRISPR/Cas9 genome editing introduction and optimization in the non-model insect Pyrrhocoris apterus
The CRISPR/Cas9 technique is widely used in experimentation with human cell lines as well as with other model systems, such as mice Mus musculus, zebrafish Danio reiro, and the fruit fly Drosophila melanogaster. However, publications describing the use of CRISPR/Cas9 for genome editing in non-model organisms, including...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
615089
Crystal channeling to extract a high energy hadron beam from an accelerator
A new generation of parasitic beam extraction of high energy particles from an accelerator is proposed in CRYSBEAM. Instead of massive magnetic kickers, bent thin crystals trapping particles within the crystal lattice planes are used. This type of beam manipulation opens new fields of investigation of fundamental inter...
[ "Fundamental Constituents of Matter", "Condensed Matter Physics", "Universe Sciences", "Systems and Communication Engineering" ]
241196
Cooperation among strangers: experiments with social norms, institutions, and money
We focus on understanding norms, behavioral traits, and institutions that can promote cooperation in societies of strangers. Many economic interactions in modern societies are among anonymous individuals who meet occasionally and do not know each others&apos; history. While cooperation in social dilemma situations amon...
[ "Institutions, Governance and Legal Systems", "Individuals, Markets and Organisations" ]
222701
Panoramix: platform for the operation and optimization in real-time of mixed autonomous fleets .
The overall objective of this project is to provide the first Matching, Dispatching and Routing platform for the operation and optimization of autonomous vehicles (AVs) fleets. AVs will be widely adopted in the coming decade reaching 20 million fully deployed AVs by 2025, making the mobility industry to face the follo...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
171540
Low cost solar absorption cooling
Solar Polar is an established product development company that specialises in innovative solar heating and cooling technology. The company’s main focus to date has been the development of an innovative low cost solar cooling technology. Our innovative technology, for which we have been awarded a US patent, features a ...
[ "Products and Processes Engineering", "Earth System Science" ]
10.1038/s41598-017-02081-9
In-situ STEM imaging of growth and phase change of individual CuAl<inf>X</inf> precipitates in Al alloy
Age-hardening in Al alloys has been used for over a century to improve its mechanical properties. However, the lack of direct observation limits our understanding of the dynamic nature of the evolution of nanoprecipitates during age-hardening. Using in-situ (scanning) transmission electron microscopy (S/TEM) while heat...
[ "Condensed Matter Physics", "Materials Engineering" ]
interreg_721
Corridor 24 Development Rotterdam-Genoa
CODE24 intends the interconnection of economic development. spatial. transport and ecological planning. The projects area of Corridor 24 covers a number of the most important economic regions in Europe within this major European North-South transport corridor across NL. D. CH and IT linking the North sea port Rotterdam...
[ "Products and Processes Engineering", "Human Mobility, Environment, and Space" ]
759296
Engineering T cells and B cells for Immunotherapy using V(D)J recombination
T cell engineering has shown clinical success mainly in haematological cancers, but scaling up is challenging due to reliance on ex vivo manipulations. In addition, B cell engineering has not shown therapeutic efficacy to date. Here, we propose a novel immunotherapy approach, allowing safe and efficient engineering of ...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1063/1.3525147
From Caging To Rouse Dynamics In Polymer Melts With Intramolecular Barriers A Critical Test Of The Mode Coupling Theory
By means of computer simulations and solution of the equations of the Mode Coupling Theory (MCT), we investigate the role of the intramolecular barriers on several dynamic aspects of non-entangled polymers. The investigated dynamic range extends from the caging regime characteristic of glass-formers to the relaxation o...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
184576
Safeguarding cultural heritage through technical and organisational resources management
Starting from previous research experiences and tangible outcomes, STORM proposes a set of novel predictive models and improved non-invasive and non-destructive methods of survey and diagnosis, for effective prediction of environmental changes and for revealing threats and conditions that could damage cultural heritage...
[ "Earth System Science", "Products and Processes Engineering", "Computer Science and Informatics", "Systems and Communication Engineering", "Studies of Cultures and Arts" ]
10.1038/nmeth.3111
Optogenetics: The age of light
The optogenetic revolution is transforming neuroscience. The dramatic recent progress in using light to both control and read out neural activity has highlighted the need for better probes, improved light delivery and more careful interpretation of results, which will all be required for optogenetics to fully realize i...
[ "Neuroscience and Disorders of the Nervous System", "Systems and Communication Engineering" ]
US 56249205 A
Brake assembly, particularly for a hydraulic wheel drive
A brake assembly, in particular of a hydraulic wheel drive, comprising a disk package formed of a plurality of outer disks and corresponding inner disks, and compressible a piston assembly for braking. A first hydraulic cycle acts on the piston assembly for driving braking and a second hydraulic cycle acts on the pisto...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1073/pnas.1221766111
Integration of hormonal signaling networks and mobile microRNAs is required for vascular patterning in Arabidopsis roots
As multicellular organisms grow, positional information is continually needed to regulate the pattern in which cells are arranged. Inthe Arabidopsis root, most cell types are organized in a radiallysymmetric pattern; however, a symmetry-breaking event generates bisymmetric auxin and cytokinin signaling domains in thest...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
647051
The tiny and the fast: the role of subcortical sensory structures in human communication
In Europe, approximately one hundred million people are impaired in their communication abilities. These include people with autism spectrum disorders (ca. 3 million) and individuals with dyslexia (ca. 50 million). Current neuroscience research typically associates cognitive functions including communication abilities ...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
W2246417048
Effect of Mixed-Phase TiO<sub>2</sub>/PVA Nanofibers on the Degradation on Methyl Orange
We report on the synthesis of nanostructured TiO 2 for various structural phases and observed the rate of degradation of methyl orange (MO) upon UV irradiation. Mixed phase nanocrystalline TiO 2 at temperature of 800°C shows higher rate of degradation of MO with the rate of 0.0203/min compared to other phases. This rat...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Materials Engineering" ]
CA 2252831 A
ILLUMINATED ASSEMBLY FOR A SWITCH/OUTLET
An illuminating apparatus for a wall switch (20) or outlet (2) that has a pair of terminals (4, 5) across which an electric potential is available, including an electroluminescent lamp plate (17) having first and second electrode deposits (14, 15) on a surface thereof, and a contact plate (12) disposed between the wall...
[ "Systems and Communication Engineering", "Materials Engineering" ]
10.1145/2661229.2661257
Rendering Volumetric Haptic Shapes In Mid Air Using Ultrasound
We present a method for creating three-dimensional haptic shapes in mid-air using focused ultrasound. This approach applies the principles of acoustic radiation force, whereby the non-linear effects of sound produce forces on the skin which are strong enough to generate tactile sensations. This mid-air haptic feedback ...
[ "Condensed Matter Physics", "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1038/cdd.2012.74
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
Endoplasmic reticulum stress is emerging as an important modulator of different pathologies and as a mechanism contributing to cancer cell death in response to therapeutic agents. In several instances, oxidative stress and the onset of endoplasmic reticulum (ER) stress occur together; yet, the molecular events linking ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]