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W1979400516
The Professor Position and the Single-Stance Flexion Test May Clarify the Effect of Lumbar Spinal Stenosis or Pseudostenosis on Lower-Extremity Symptoms
The effect of lumbar spinal stenosis on lower-extremity symptoms is often hard to ascertain in patients with multiple possible causes of symptoms. A positive response to two described maneuvers performed by patients in the office involving flexion of the spine can strongly corroborate the contribution of lumbar spinal ...
[ "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.3762/bjoc.13.67
Fluorescent carbon dots from mono- and polysaccharides: synthesis, properties and applications
Fluorescent carbon dots (FCDs) are an emerging class of nanomaterials made from carbon sources that have been hailed as potential non-toxic replacements to traditional semiconductor quantum dots (QDs). Particularly in the areas of live imaging and drug delivery, due to their water solubility, low toxicity and photo- an...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Materials Engineering" ]
185792
Advanced material for cost effective and high density ultracapacitors for the transport sector
To meet carbon emissions targets, transport must become more energy efficient. Currently only 14%–30% of the energy from the fuel you put in a vehicle is used to move it down the road, depending on the drive cycle. The rest of the energy is lost to engine and driveline inefficiencies or used to power accessories. Ther...
[ "Materials Engineering", "Products and Processes Engineering", "Synthetic Chemistry and Materials" ]
10.1103/PhysRevB.95.035416
Theory of plasmonic effects in nonlinear optics: The case of graphene
We develop a microscopic large-N theory of electron-electron interaction corrections to multilegged Feynman diagrams describing second- and third-order non-linear-response functions. Our theory, which reduces to the well-known random-phase approximation in the linear-response limit, is completely general and is useful ...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
2730985
New geochemical approach to reconstruct tropical palaeo-atmospheric dynamics
Tropical climates are changing rapidly in the most populated regions of the planet. The changes largely arise from alterations in the Hadley circulation driven by natural and anthropogenic factors, whose relative roles and temporal variability are unclear. These knowledge gaps are in part due to the shortage of methods...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
682626
Migrant Life Course and Legal Status Transition
When does citizenship provide a boost to migrant integration? A fast-track to citizenship can maximise the potential for settlement success, though too short a pathway can disincentivise integration. Not all migrants have an equal interest in naturalising and some are discouraged by restrictive policies. Yet little is ...
[ "Institutions, Governance and Legal Systems", "Human Mobility, Environment, and Space", "The Social World and Its Interactions" ]
10.1039/c7cp04748g
Interplay between the folding mechanism and binding modes in folding coupled to binding processes
Proteins that fold upon binding to their partners exhibit complex binding behavior such as induced-fit. Using molecular simulations we find that the ability to bind via induced-fit requires the disordered protein to fold downhill. Thus induced-fit appears as a manifestation of a conformational rheostat.
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences" ]
10.1007/978-1-4939-8820-4_21
Solubis Optimizing Protein Solubility By Minimal Point Mutations
Protein solubility is adapted to endogeneous protein abundance in the cell where protein folding is also assisted by multiple chaperones. During recombinant protein production, purification and storage proteins are frequently handled at concentrations that are several orders of magnitude above their physiological conce...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering" ]
10.1063/1.4954650
Optofluidic Distributed Feedback Lasers With Evanescent Pumping Reduced Threshold And Angular Dispersion Analysis
We demonstrate an evanescently pumped water-based optofluidic distributed feedback (DFB) laser with a record low pump threshold of ETH=520 nJ. The low threshold results from an optimized mode shape, which is achieved by a low refractive index substrate, and from the use of a mixed-order DFB grating. Investigating the p...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1063/1.4927857
Rayleigh Taylor Instability Under An Inclined Plane
We revisit the canonical Rayleigh-Taylor instability and investigate the case of a thin film of fluid upon the underside of an inclined plane. The presence of a natural flow along the plane competes with the conventional droplet forming instability. In particular, experiments reveal that no drops form for inclinations ...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1016/j.neuroimage.2016.12.031
Tracking thoughts: Exploring the neural architecture of mental time travel during mind-wandering
The capacity to imagine situations that have already happened or fictitious events that may take place in the future is known as mental time travel (MTT). Studies have shown that MTT is an important aspect of spontaneous thought, yet we lack a clear understanding of how the neurocognitive architecture of the brain cons...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1109/GLOCOM.2017.8254901
Robust Location Aided Beam Alignment In Millimeter Wave Massive Mimo
Location-aided beam alignment has been proposed recently as a potential approach for fast link establishment in millimeter wave (mmWave) massive MIMO (mMIMO) communications. However, due to mobility and other imperfections in the estimation process, the spatial information obtained at the base station (BS) and the user...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1177/0956797616643924
Pupillary Contagion In Infancy Evidence For Spontaneous Transfer Of Arousal
Pupillary contagion-responding to pupil size observed in other people with changes in one's own pupil-has been found in adults and suggests that arousal and other internal states could be transferred across individuals using a subtle physiological cue. Examining this phenomenon developmentally gives insight into its or...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
771550
How does the brain organize sounds into auditory scenes?
Real-world listening involves making sense of the numerous competing sound sources that exist around us. The neuro-computational challenge faced by the brain is to reconstruct these sources from the composite waveform that arrives at the ear; a process known as auditory scene analysis. While young normal hearing listen...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
833577
Resolving Precariousness: Advancing the Theory and Measurement of Precariousness across the paid/unpaid work continuum
The traditional dichotomy of paid (productive or waged) versus unpaid (reproductive or unwaged) work marginalizes unpaid work when conceptualizing precariousness, i.e. the exposure to unpredictability towards an individual’s future. It also neglects several types of unpaid work such as care work, work as a precondition...
[ "The Social World and Its Interactions", "Individuals, Markets and Organisations" ]
EP 17150501 A
ELECTRIC LUMINAIRE
Um eine elektrische Leuchte, zumindest aufweisend ein Leuchtengehäuse mit Boden und Seitenwänden, mit mindestens einem Reflektor, zudem aufweisend eine Leuchteneinheit mit Kühler und mindestens einer lichtemittierenden Diode (LED), die von dem Reflektor umgeben oder zwischen den Reflektoren angeordnet ist, wobei der Li...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1146/annurev-pharmtox-010611-134636
Chronic pain states: Pharmacological strategies to restore diminished inhibitory Spinal pain control
Potentially noxious stimuli are sensed by specialized nerve cells named nociceptors, which convey nociceptive signals from peripheral tissues to the central nervous system. The spinal dorsal horn and the trigeminal nucleus serve as first relay stations for incoming nociceptive signals. At these sites, nociceptor termin...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1016/j.stem.2011.07.008
EPO and super-EPO: Erythropoietins direct neoangiogenesis by cardiac progenitor cells
Erythropoietin, the red blood cell-making cytokine, is also a potential cytoprotective agent in heart disease. In this issue of Cell Stem Cell, Hoch et al. (2011) use two heart failure models, including chemotherapeutic cardiotoxicity, to reveal a mechanistic connection between reduced cardiomyocyte production of eryth...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing" ]
W2162497105
A tale of a tail: Structural insights into the conformational properties of the polyglutamine protein ataxin-3
Ataxin-3 is the protein responsible for the neurodegenerative polyglutamine disease Spinocerebellar ataxia type 3. Full structural characterisation of ataxin-3 is required to aid in understanding the mechanism of disease. Despite extensive study, little is known about the conformational properties of the full-length pr...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
3733961
Negotiating religion: coptic orthodox diaspora communities. shifting identities, needs, and relations from egypt to europe and back
NEGOTIA aims to analyse the Coptic Orthodox diaspora communities in Europe with specific regard to three key aspects: identities, needs, and relations, in order to reconstruct the theoretical-practical framework of religious mediation.Its first goal is to examine the origins and the history of these communities, their ...
[ "Studies of Cultures and Arts", "Human Mobility, Environment, and Space", "The Study of the Human Past" ]
W1979202774
Positional accuracy of the Google Earth terrain model derived from stratigraphic unconformities in the Big Bend region, Texas, USA
The Google Earth terrain model could prove beneficial for extraction of positional data in the future. At present, only an aging independent benchmark study (Potere, D., 2008. Horizontal position accuracy of Google Earth's high-resolution imagery archive. Sensors, 8, 7973–7981) provides constraints on positional accura...
[ "Earth System Science", "Systems and Communication Engineering" ]
10.1103/PhysRevA.96.042326
Investigating Einstein-Podolsky-Rosen steering of continuous-variable bipartite states by non-Gaussian pseudospin measurements
Einstein-Podolsky-Rosen (EPR) steering is an asymmetric form of correlations which is intermediate between quantum entanglement and Bell nonlocality, and can be exploited as a resource for quantum communication with one untrusted party. In particular, steering of continuous-variable Gaussian states has been extensively...
[ "Fundamental Constituents of Matter" ]
10.1016/j.spa.2017.02.013
Fluctuations of the total number of critical points of random spherical harmonics
We determine the asymptotic law for the fluctuations of the total number of critical points of random Gaussian spherical harmonics in the high degree limit. Our results have implications on the sophistication degree of an appropriate percolation process for modelling nodal domains of eigenfunctions on generic compact s...
[ "Mathematics" ]
EP 17848440 A
IMAGE PROCESSING DEVICE AND LIGHT DISTRIBUTION CONTROL SYSTEM
The present invention provides a low-cost image processing device that is capable of reducing a processing amount for detecting light spots in comparison to the prior art, and is capable of detecting headlights and tail lamps of vehicles with high precision. The present invention pertains to an image processing device ...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1002/mas.21464
Copper-catalyzed reactions: Research in the gas phase
Electrospray ionization mass spectrometry (ESI-MS) is becoming an important tool for mechanistic studies in organic and organometallic chemistry. It allows investigation of reaction mixtures including monitoring of reactants, products, and intermediates, studying properties of the intermediates and their reactivity. St...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
336319
The Social Life of State Deportation Regimes: A Comparative Study of the Implementation Interface
The deportation of irregular migrants is a burning issue in public debates all around the world. Most states invest heavily in effective deportation regimes, but when it comes to implementation, deportation regimes are notorious for not achieving their declared goals. Everywhere, marked discrepancies persist between de...
[ "The Social World and Its Interactions", "Institutions, Governance and Legal Systems" ]
10.1002/anie.201603886
A Nanoarchitecture Based on Silver and Copper Oxide with an Exceptional Response in the Chlorine-Promoted Epoxidation of Ethylene
The selective oxidation of ethylene to ethylene epoxide is highly challenging as a result of competing reaction pathways leading to the deep oxidation of both ethylene and ethylene oxide. Herein we present a novel catalyst based on silver and copper oxide with an excellent response in the selective oxidation pathway to...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
10.1186/1471-2164-14-853
Reprogramming Of Lysosomal Gene Expression By Interleukin 4 And Stat6
Lysosomes play important roles in multiple aspects of physiology, but the problem of how the transcription of lysosomal genes is coordinated remains incompletely understood. The goal of this study was to illuminate the physiological contexts in which lysosomal genes are coordinately regulated and to identify transcript...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy", "Cell Biology, Development, Stem Cells and Regeneration" ]
interreg_595
CCAlps. Creative companies in Alpine Space
Creativity is a modern lever to sustainable growth, considered a fundamental asset to enable a behavioural change. To promote a competitive growth in the Alpine area it is important to bet on creative industries, because of their capability to trigger transformation in a territory. The main objective of CCAlps is there...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems", "Human Mobility, Environment, and Space" ]
W2399246222
Wind energy resources on Phuquoc Island, Vietnam
ABSTRACTThis study analyzes the wind energy resources on Phuquoc Island, Vietnam. Daily wind data are collected from 2005 to 2011 in this study. The annual mean speed and power density are 6 m/s and 355 W/m2, respectively. Results show that more than 35% of the wind energy comes from the northwest. In this study, a 75 ...
[ "Products and Processes Engineering", "Earth System Science" ]
10.1080/21541264.2016.1203628
Specialization Versus Conservation How Pol I And Pol Iii Use The Conserved Architecture Of The Pre Initiation Complex For Specialized Transcription
Here, we discuss the overall architecture of the RNA polymerase I (Pol I) and III (Pol III) core enzymes and their associated general transcription factors in the context of models of the Pol I and Pol III pre-initiation complexes, thereby highlighting potential functional adaptations of the Pol I and Pol III enzymes t...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1214/EJP.v18-2387
A simple proof of distance bounds for Gaussian rough paths
We derive explicit distance bounds for Stratonovich iterated integrals along two Gaussian processes (also known as signatures of Gaussian rough paths) based on the regularity assumption of their covariance functions. Similar estimates have been obtained recently in [Friz-Riedel, AIHP, to appear]. One advantage of our a...
[ "Mathematics" ]
DE 9702030 W
PIPE FITTING
This invention concerns a pipe fitting which consists of a press fitting of corrosion-resistant material which has at least one section extending outwards or inwards and having a seal ring and a cylindrical area adjacent to it. This cylindrical area has a crease at the end of the extension and has a line pipe out of co...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1007/s00330-012-2592-1
Assessment of grating-based X-ray phase-contrast CT for differentiation of invasive ductal carcinoma and ductal carcinoma in situ in an experimental ex vivo set-up
Objective: Limited contrast between healthy and tumour tissue is a limiting factor in mammography and CT of the breast. Phase-contrast computed tomography (PC-CT) provides improved soft-tissue contrast compared with absorption-based techniques. In this study, we assessed the technical feasibility of grating-based PC-CT...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
DE 10207162 A
Verwertungseinrichtung von Grauwasser
Bei einer Einrichtung zur Verwertung von Abwasser, insbesondere Abwasser von Bade- und/oder Duschwannen, wobei Abwasser in einem Grauwassertank gesammelt wird, ist vorgeschlagen, dass der Abwasserstrom über eine Trennvorrichtung geführt wird, die klares Abwasser in den Grauwassertank und trübes Abwasser in die Abwasser...
[ "Products and Processes Engineering" ]
W1982088425
The integrated landscape of driver genomic alterations in glioblastoma
Glioblastoma is one of the most challenging forms of cancer to treat. Here we describe a computational platform that integrates the analysis of copy number variations and somatic mutations and unravels the landscape of in-frame gene fusions in glioblastoma. We found mutations with loss of heterozygosity in LZTR1, encod...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Cell Biology, Development, Stem Cells and Regeneration", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1007/JHEP10(2016)053
Matched Predictions For The B Overline B H Cross Section At The 13 Tev Lhc
We present up-to-date matched predictions for the $$ b\overline{b}H $$ inclusive cross section at the LHC at $$ \sqrt{s}=13 $$ TeV. Using a previously developed method, our predictions consistently combine the complete NLO contributions that are present in the 4-flavor scheme calculation, including finite b-quark mas...
[ "Fundamental Constituents of Matter" ]
695709
The origins of dendritic computation within mammalian neural circuits
This proposal aims to address a simple question: what is the fundamental unit of computation in the brain? Answering this question is crucial not only for understanding how the brain works, but also if we are to build accurate models of brain function, which require abstraction based on identification of the essential ...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1016/j.cell.2017.05.018
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Alzheimer's disease (AD) is a detrimental neurodegenerative disease with no effective treatments. Due to cellular heterogeneity, defining the roles of immune cell subsets in AD onset and progression has been challenging. Using transcriptional single-cell sorting, we comprehensively map all immune populations in wild-ty...
[ "Neuroscience and Disorders of the Nervous System", "Immunity, Infection and Immunotherapy", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1103/PhysRevE.93.063302
Entropic lattice Boltzmann model for gas dynamics: Theory, boundary conditions, and implementation
We present in detail the recently introduced entropic lattice Boltzmann model for compressible flows [N. Frapolli, Phys. Rev. E 92, 061301(R) (2015)PLEEE81539-375510. 1103/PhysRevE. 92. 061301]. The model is capable of simulating a wide range of laminar and turbulent flows, from thermal and weakly compressible flows t...
[ "Fundamental Constituents of Matter", "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1103/PhysRevB.90.100403
Anomalous and planar Nernst effects in thin films of the half-metallic ferromagnet La2/3Sr1/3MnO3
We report the planar and anomalous Nernst effects in epitaxial thin films of spin polarized La2/3Sr1/3MnO3. The thermal counterpart of the anomalous Hall effect in this material (i. e. , the anomalous Nernst effect) shows an extreme sensitivity to any parasitic thermal gradient, resulting in large asymmetric voltages u...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1021/ja4017842
Mechanochemical synthesis of chemically stable isoreticular covalent organic frameworks
Three thermally and chemically stable isoreticular covalent organic frameworks (COFs) were synthesized via room-temperature solvent-free mechanochemical grinding. These COFs were successfully compared with their solvothermally synthesized counterparts in all aspects. These solvent-free mechanochemically synthesized COF...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
W1986472843
Liquidation equilibrium with seniority and hidden CDO
The aim of our paper is to price credit derivatives written on a single name when this name is a bank. Indeed, due to the special structure of the balance sheet of a bank and to the interconnections with other institutions of the financial system, the standard pricing formulas do not apply and their use can imply sever...
[ "Mathematics", "Computer Science and Informatics" ]
interreg_3890
VIA NOVA – Healthy Mobility and Intelligent Intermodality In Alpine Areas
VIANOVA with partners from all the 7 Alpine countries is a project that aims to reduce car traffic (shift solo car trips) and at the same time to motivate the inhabitants for non-motorised and sustainable modes of transport based on physical activities (cycling & walking). A cross-sectoral approach (land use planning -...
[ "Human Mobility, Environment, and Space", "Products and Processes Engineering" ]
W2914797718
Landscape-Based Habitat Engineering for Sugarcane Ecosystem: A Green Technological Option for Pest Management
A conceptual model of habitat augmentation for subtropical sugarcane ecosystem has been established to enhance its self-regulatory capacity for pest protection by linking species interrelationships and their trophic interactions. In order to ensure adequate number of predators and parasitoids to deliver the desired lev...
[ "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering" ]
216814
Antimicrobial flexible polymers for its use in hospital environments
FLEXPOL aims to develop a pilot line for the production of a cost effective antimicrobial (AM) adhesive film for its use in hospitals. The obtained adhesive film will inhibit growth of a wide range of microbes and will be suitable for high-touch surfaces, providing a durable protection with good resistance. It will as...
[ "Materials Engineering", "Products and Processes Engineering", "Synthetic Chemistry and Materials" ]
10.1021/acs.analchem.8b02349
Estimating Interprotein Pairwise Interaction Energies in Cell Lysates from a Single Native Mass Spectrum
A powerful method to determine the energetic coupling between amino acids is double mutant cycle analysis. In this method, two residues are mutated separately and in combination and the energetic effects of the mutations are determined. A deviation of the effect of the double mutation from the sum of effects of the sin...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W1981342765
An insight into the bread bubble structure: An X-ray microtomography approach
Abstract An insight into bread bubble structure is presented in this study. In particular, different types of bread have been investigated differing both in the yeast and water contents and therefore leading to distinct cellular structures. X-ray microtomography was used in combination with advanced statistical methods...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
interreg_1938
PEER-to-peer network of INNOvation agencies and business schools developing a novel transnational qualification programme on AdVanced Manufacturing for the needs of Central European SME
Central Europe has a strong industrial tradition which is recently offset by an urgent need for modernisation and re-industrialisation. CE companies, spec. SME, are urgently challenged to adopt innovative advanced manufacturing (AVM) processes in order to enhance their competitiveness and gain access to transnational A...
[ "Products and Processes Engineering", "Individuals, Markets and Organisations" ]
259196
NEW FRONTIERS IN PLASMON OPTICS: FROM NANOCHEMISTRY TO QUANTUM OPTICS
At this point in time where plasmon optics has become a mature field of research, we propose here to create new bridges with other scientific disciplines in which the optical properties of plasmonic nanostructures could successfully address major roadblocks. The proposed scientific project consists of two independent ...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
W1969466261
Parametric study and optimization of a RCCI (reactivity controlled compression ignition) engine fueled with methanol and diesel
Abstract By integrating an updated multi-dimensional model and the NSGA-II (non-dominated sorting genetic algorithm II), the combustion of a RCCI (reactivity controlled compression ignition) engine fueled with methanol/diesel was optimized. Based on the optimization results, parametric study was performed by varying en...
[ "Products and Processes Engineering", "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1109/MIS.2017.12
Online Prediction Via Continuous Artificial Prediction Markets
Prediction markets are well-established tools for aggregating information from diverse sources into accurate forecasts. Their success has been demonstrated in a wide range applications, including presidential campaigns, sporting events, and economic outcomes. Recently, they've been introduced to the machine learning co...
[ "Computer Science and Informatics", "Individuals, Markets and Organisations" ]
10.1002/cmmi.1515
MRI contrast variation of thermosensitive magnetoliposomes triggered by focused ultrasound: A tool for image-guided local drug delivery
Improved drug delivery control during chemotherapy has the potential to increase the therapeutic index. MRI contrast agent such as iron oxide nanoparticles can be co-encapsulated with drugs in nanocarrier liposomes allowing their tracking and/or visualization by MRI. Furthermore, the combination of a thermosensitive li...
[ "Physical and Analytical Chemical Sciences", "Prevention, Diagnosis and Treatment of Human Diseases", "Materials Engineering" ]
10.1038/nn.3729
Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human
Neuronal migration disorders such as lissencephaly and subcortical band heterotopia are associated with epilepsy and intellectual disability. DCX, PAFAH1B1 and TUBA1A are mutated in these disorders; however, corresponding mouse mutants do not show heterotopic neurons in the neocortex. In contrast, spontaneously arisen ...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1103/PhysRevD.87.094503
Thirring model at finite density in 0+1 dimensions with stochastic quantization: Crosscheck with an exact solution
We consider a generalized Thirring model in 0+1 dimensions at finite density. In order to deal with the resulting sign problem we employ stochastic quantization, i. e. , a complex Langevin evolution. We investigate the convergence properties of this approach and check in which parameter regions complex Langevin evoluti...
[ "Fundamental Constituents of Matter", "Mathematics" ]
10.3389/fnmol.2013.00043
A comprehensive characterization of the nuclear microRNA repertoire of post-mitotic neurons
MicroRNAs (miRNAs) are small non-coding RNAs with important functions in the development and plasticity of post-mitotic neurons. In addition to the well-described cytoplasmic function of miRNAs in post-transcriptional gene regulation, recent studies suggested that miRNAs could also be involved in transcriptional and po...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1051/0004-6361/201630126
Fragmentation And Disk Formation In High Mass Star Formation The Alma View Of G351 77 0 54 At 0 06 Resolution
Aims: We resolve the small-scale structure around the high-mass hot core region G351. 77-0. 54 to investigate its disk and fragmentation properties. Methods: Using ALMA at 690GHz with baselines exceeding 1. 5km, we study the dense gas, dust and outflow emission at an unprecedented spatial resolution of 0. 06" (130AU@2....
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
10.1016/j.forpol.2017.04.014
Mapping certified forests for sustainable management - A global tool for information improvement through participatory and collaborative mapping
There are currently no spatially explicit, openly accessible data available on forest certification below national level, so understanding the drivers of certification in the past, examining the scope for further certification and using this information for development of future sustainable forest management strategies...
[ "Earth System Science", "Computer Science and Informatics" ]
W2587070108
Performative contradiction and revolution : reconsidering Romania
This thesis discusses the Romanian Revolution of 1989 through the critiques of its authenticity that have emerged in the field of critical theory over the past twenty-five years. It applies a different theoretical model for interpretation, that of performative contradiction, and reconsiders accusations of inauthenticit...
[ "Texts and Concepts", "The Study of the Human Past", "The Social World and Its Interactions" ]
US 201816195105 A
FULLY ILLUMINATED APPARATUS AND METHOD
Embodiments of the present disclosure provide a method and apparatus for illuminating. An exemplary apparatus includes a substrate having a longitudinal axis, and a first plurality of spaced apart fingers extending perpendicular to the longitudinal axis from a first side of the substrate. The apparatus further includes...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1007/978-981-10-4053-5_1
Introduction Current Challenges Of Global History In East Asian Historiographies
The origins of this book, being the first in the new series on Palgrave Studies in Comparative Global History, date from the early projects and common synergies that Lucio de Sousa and I started respectively in Japan and China. The GECEM project, funded by the ERC, and the Global History Network in China (GHN) has cont...
[ "The Study of the Human Past", "The Social World and Its Interactions" ]
10.1016/j.gloenvcha.2015.02.001
Rapid ecosystem change challenges the adaptive capacity of local environmental knowledge
The use of Local Environmental Knowledge has been considered as an important strategy for adaptive management in the face of Global Environmental Change. However, the unprecedented rates at which global change occurs may pose a challenge to the adaptive capacity of local knowledge systems. In this paper, we use the con...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science", "Human Mobility, Environment, and Space" ]
219957
Revitalizing the clinical potential of type i ifns in fighting influenza a virus infections with actaferon.
Based on their antiviral and antitumor effect, type I interferons (IFNs) were believed to be the miracle drug to tackle viruses and cancer. However, clinical IFN applications remained limited due to severe side effects resulting from widespread cellular sensitivity to IFN, which limits the administrable doses. Hence, t...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
634674
Lucero - smart optofluidic micromanipulation of biological samples
The goal of Lucero is to create autonomous micromanipulation solutions for biological applications integrating optical manipulation, microfluidics, and machine intelligence. Single-cell analysis is critical in many biomedical applications, such as clinical trials, in-vitro fertilization, forensic analysis, and single-c...
[ "Computer Science and Informatics", "Systems and Communication Engineering", "Products and Processes Engineering", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
W584613241
1927 and the rise of modern America
When Charles Lindbergh landed at LeBourget Airfield on May 21, 1927, his transatlantic flight symbolized the new era - not only in aviation but also in American culture. The 1920s proved to be a transitional decade for the United States, shifting the nation from a production-driven economy to a consumption-based one, w...
[ "Texts and Concepts", "The Social World and Its Interactions", "Studies of Cultures and Arts" ]
W3039997617
PREASC
The increasing functionality of electronic systems due to the constant evolution of the market requirements makes the non-functional aspects of such systems (e.g., energy consumption, area overhead, or performance) a major concern in the design process. Approximate computing is a promising way to optimize these criteri...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
interreg_394
Bernina Terra Glacialis._x000D_ Study and development_x000D_ of a valuable natural and cultural heritage, with innovative approaches
The project takes note of the awareness of the impact that climate change is having on the environment and on the the Alpine communities life. It starts a process of informing people, companies and administrations, studying new strategies and professions related to traditional cultural heritage and the environment. The...
[ "Earth System Science", "Human Mobility, Environment, and Space", "Studies of Cultures and Arts" ]
10.1145/2897824.2925911
Synthesis Of Filigrees For Digital Fabrication
Filigrees are thin patterns found in jewelry, ornaments and lace fabrics. They are often formed of repeated base elements manually composed into larger, delicate patterns. Digital fabrication simplifies the process of turning a virtual model of a filigree into a physical object. However, designing a virtual model of a ...
[ "Computer Science and Informatics", "Materials Engineering" ]
W1978519745
Describing avifaunal richness with functional and structural bioindicators derived from advanced airborne remotely sensed data
We investigate whether the richness of distinct avian guilds species grouped together based on similar exploitation of environmental resources can be described using indicators of ecosystem function and tree species diversity derived from hyperspectral data and/or aspects of vegetation structure derived from lidar. Bir...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Computer Science and Informatics" ]
169421
Selectively targeting oscillations in parkinson's disease: causal effects of the beta-rhythm on motor control
Parkinson’s disease is a frequent and disabling neurological disorder, which heavily impairs patients’ ability to perform and control movements. Electrical stimulation of a deep-seated brain region, the subthalamic nucleus (STN), has been shown to significantly improve patients’ motor function and quality of life. Rece...
[ "Neuroscience and Disorders of the Nervous System", "Prevention, Diagnosis and Treatment of Human Diseases", "Systems and Communication Engineering" ]
10.1088/0004-637X/786/2/137
High Resolution Observations Of The Shock Wave Behavior For Sunspot Oscillations With The Interface Region Imaging Spectrograph
We present the first results of sunspot oscillations from observations by the Interface Region Imaging Spectrograph. The strongly nonlinear oscillation is identified in both the slit-jaw images and the spectra of several emission lines formed in the transition region and chromosphere. We first apply a single Gaussian f...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
10.1063/1.3614036
Role Of Heavy Ion Co Implantation And Thermal Spikes On The Development Of Dislocation Loops In Nanoengineered Silicon Light Emitting Diodes
Microstructural and electroluminescence measurements are carried out on boron implanted dislocation engineered silicon light emitting diodes (LEDs) co-implanted with the rare earth thulium to provide wavelength tuning in the infra-red. Silicon LEDs operating in the range from 1. 1–1. 35 μm are fabricated by co-implanta...
[ "Condensed Matter Physics", "Materials Engineering", "Synthetic Chemistry and Materials" ]
10.1039/C6CC03031A
Shrink Wrapping Redox Active Crystals Of Polyoxometalate Open Frameworks With Organic Polymers Via Crystal Induced Polymerisation
We report examples of crystal surface modification of polyoxometalate open frameworks whereby the use of pyrrole or aniline as monomers leads to the formation of the corresponding polymers via an oxidative polymerization process initiated by the redox active POM scaffolds. Guest-exchange experiments demonstrate that th...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1021/acsami.7b13273
Covalently Attached Antimicrobial Surfaces Using BODIPY: Improving Efficiency and Effectiveness
The development of photoactivated antimicrobial surfaces that kill pathogens through the production of singlet oxygen has proved very effective in recent years, with applications in medical devices and hospital touch surfaces, to improve patient safety and well being. However, many of these surfaces require a swell-enc...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering", "Synthetic Chemistry and Materials" ]
W2127757756
Decoloration and detoxification of effluents by ionizing radiation
Abstract Three distinct textile samples were investigated for color and toxicity (S1–chemical/textile industry; S2–final textile effluent; S3 - standard textile produced effluent–untreated blue). Radiation processing of these samples were carried out at Dynamitron Electron Beam Accelerator and color and toxicity remova...
[ "Products and Processes Engineering", "Environmental Biology, Ecology and Evolution" ]
10.1109/ACCESS.2018.2816781
Performance Analysis Of Nanoelectromechanical Relay Based Field Programmable Gate Arrays
The energy consumption of field-programmable gate arrays (FPGA) is dominated by leakage currents and dynamic energy associated with programmable interconnect. An FPGA built entirely from nanoelectromechanical (NEM) relays can effectively eliminate leakage energy losses, reduce the interconnect dynamic energy, operate a...
[ "Computer Science and Informatics", "Systems and Communication Engineering", "Materials Engineering" ]
10.1007/978-3-642-31762-0_2
The Cost Ic0701 Verification Competition 2011
This paper reports on the experiences with the program verification competition held during the FoVeOOS conference in October 2011. There were 6 teams participating in this competition. We discuss the three different challenges that were posed and the solutions developed by the teams. We conclude with a discussion abou...
[ "Computer Science and Informatics" ]
W2060458887
Learning Situations within an Informal Context: Case Study (Ethnology and Folklore Course)
Abstract The informal framework could be identified as an accompanying tool to be used for the higher-level education, in particular when it comes to specific disciplines that, on account of subject matter and technique, entail a pragmatic side at the same time. One case specific case refers to the discipline Ethnology...
[ "Studies of Cultures and Arts", "The Social World and Its Interactions" ]
10.1038/s41467-017-01130-1
Actomyosin pulsation and flows in an active elastomer with turnover and network remodeling
Tissue remodeling requires cell shape changes associated with pulsation and flow of the actomyosin cytoskeleton. Here we describe the hydrodynamics of actomyosin as a confined active elastomer with turnover of its components. Our treatment is adapted to describe the diversity of contractile dynamical regimes observed i...
[ "Condensed Matter Physics", "Cell Biology, Development, Stem Cells and Regeneration" ]
W184608981
2009 influenza A (H1N1): a clinical review
Since the onset of the 2009 influenza A (H1N1) pandemic, the virus has caused significant morbidity and mortality. Most cases of 2009 H1N1 have presented as mild febrile illnesses with cough, sore throat, and occasional gastrointestinal symptoms. Dyspnea has been more commonly associated with the onset of severe pulmon...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
336679
Fundamentals Of Photocatalytic Splitting of Water
Hydrogen produced by sunlight is a very promising, environmentally-friendly energy source as an alternative for increasingly scarce and polluting fossil fuels. Since the discovery of hydrogen production by photocatalytic water dissociation on a titanium dioxide (TiO2) electrode 40 years ago, much research has been aime...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1007/JHEP04(2017)157
An Algebraic Approach To The Analytic Bootstrap
We develop an algebraic approach to the analytic bootstrap in CFTs. By acting with the Casimir operator on the crossing equation we map the problem of doing large spin sums to any desired order to the problem of solving a set of recursion relations. We compute corrections to the anomalous dimension of large spin operat...
[ "Fundamental Constituents of Matter", "Mathematics" ]
CA 2015000523 W
IMPROVED MOLD BLOCK RETURN
A two stage mold block transfer station is used the exit of a moving mold tunnel to quickly move mold blocks to a clear position relative to the molded product. Once in the clear position the mold block is rotated and provided to a return drive moving the mold block back to the inlet of the moving mold tunnel. By movin...
[ "Products and Processes Engineering" ]
W1985335148
Experiment of Micro-Parts Feeding on Saw-Tooth with the Effect of the Surface Geometry Parameters
In this work, we study experimentally the effect of the geometry parameters of saw-tooth surface and micro-part on the motion of micro-parts. The experiments are performed for a range of saw-tooth pitch, p , micro-part length, l , and exciting frequency applied to the surface, f . By the use of particle tracking veloci...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1016/j.soilbio.2014.11.009
Soil characteristics determine soil carbon and nitrogen availability during leaf litter decomposition regardless of litter quality
Climate and litter quality have been identified as major drivers of litter decomposition, but our knowledge of how soil characteristics (e. g. microbial community and chemical properties) determine carbon (C) and nitrogen (N) availability derived from the decomposition of litter of different qualities is still scarce....
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
W2019719692
The Benefits of Learning Social Welfare: Lessons from Student Perspectives
It is widely assumed that most entering MSW students exhibit a primary interest in individual clinical practice but minimal understanding of or interest in welfare policy knowledge. However, this assumption is mostly based on attitudes before and at the beginning of encountering social welfare courses. Using a mixed-me...
[ "The Social World and Its Interactions" ]
10.1109/IMW.2014.6849366
Double Barrier Magnetic Tunnel Junctions With Write Read Mode Select Layer
In this study, special STT-RAM were designed, built and tested, allowing to read and write at similar voltages. This is achieved by maximizing the Spin-Transfer-Torque (STT) efficiency on the storage layer magnetization during write and minimizing it during read. In order to achieve this STT tuning, double barrier magn...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1007/s10680-018-9489-x
Fertility History and Physical and Mental Health Changes in European Older Adults
Previous studies have shown that aspects of reproductive history, such as earlier parenthood and high parity, are associated with poorer health in mid and later life. However, it is unclear which dimensions of health are most affected by reproductive history, and whether the pattern of associations varies for measures ...
[ "Physiology in Health, Disease and Ageing", "Human Mobility, Environment, and Space" ]
10.1088/2041-8205/737/1/L10
Amplitudes Of Solar Like Oscillations Constraints From Red Giants In Open Clusters Observed By Kepler
Scaling relations that link asteroseismic quantities to global stellar properties are important for gaining understanding of the intricate physics that underpins stellar pulsation. The common notion that all stars in an open cluster have essentially the same distance, age, and initial composition, implies that the stel...
[ "Universe Sciences" ]
10.1007/JHEP02(2014)091
Sterile Neutrinos In Leptonic And Semileptonic Decays
We address the impact of a modified $W \ell \nu$ coupling on a wide range of observables, such as $\tau$ leptonic and mesonic decays, leptonic decays of pseudoscalar mesons, as well as semileptonic meson decays. In particular, we concentrate on deviations from lepton flavour universality, focusing on the ratios $R_{P} ...
[ "Fundamental Constituents of Matter" ]
714658
Do early stone tools indicate a hominin ability to accumulate culture?
Cultural – not genetic – adaptations have allowed humans to colonise the planet. While discovering the roots of human culture has been described as one of the 125 most pressing scientific questions of our time (Science, 2005), it remains unclear when such forms of culture first arose in our lineage. Previous research ...
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution", "The Human Mind and Its Complexity" ]
10.1371/journal.ppat.1003473
A Type IV Pilus Mediates DNA Binding during Natural Transformation in Streptococcus pneumoniae
Natural genetic transformation is widely distributed in bacteria and generally occurs during a genetically programmed differentiated state called competence. This process promotes genome plasticity and adaptability in Gram-negative and Gram-positive bacteria. Transformation requires the binding and internalization of e...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Immunity, Infection and Immunotherapy" ]
US 2020/0026771 W
VOICE-BASED SOCIAL NETWORK
This invention presents a novel voice-based social network, where users can compose, explore, and share voice posts. Each voice post is comprised of audio, text with dictation from speech, and other optional elements such as picture, video, contact, etc. During the composition step, user speaks to the microphone, and s...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1063/1.4926345
Long Term Laser Frequency Stabilization Using Fiber Interferometers
We report long-term laser frequency stabilization using only the target laser and a pair of 5 m fiber interferometers, one as a frequency reference and the second as a sensitive thermometer to stabilize the frequency reference. When used to stabilize a distributed feedback laser at 795 nm, the frequency Allan deviation...
[ "Fundamental Constituents of Matter", "Systems and Communication Engineering" ]
310080
The Structure and Assembly of Membrane Proteins in Native Membranes studied by AFM
One of the key characteristics of life is the existence of boundaries that delineate the organism from its environment. The boundary membrane structure that defines all cells is called the plasma membrane. Membranes are constituted of a large variety of lipids and membrane proteins, key molecules for plenty vital cellu...
[ "Condensed Matter Physics", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences" ]
W2008238605
Merit of Anisodamine Combined with Opioidδ-Receptor Activation in the Protection against Myocardial Injury during Cardiopulmonary Bypass
Myocardial ischemia/reperfusion (MIR) injury easily occurrs during cardiopulmonary bypass surgery in elderly patients. In an attempt to develop an effective strategy, we employed a pig model of MIR injury to investigate the maximum rate of change of left ventricular pressure, left ventricular enddiastolic pressure, and...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W872959972
Noncirrhotic portal hypertension in a human immunodeficiency virus (HIV) infected adolescent
OBJECTIVE: To alert the pediatrician who is following up HIV-infected patients about the possibility of non-cirrhotic portal hypertension (NCPH) in this period of life, in order to avoid the catastrophic consequences of this disease as bleeding esophageal varices. CASE DESCRIPTION: A 13 years old HIV-infected patient b...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1126/scitranslmed.aaw6003
Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor cells
Acute tissue injury causes DNA damage and repair processes involving increased cell mitosis and polyploidization, leading to cell function alterations that may potentially drive cancer development. Here, we show that acute kidney injury (AKI) increased the risk for papillary renal cell carcinoma (pRCC) development and ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
205660
Re-conceptualizing party democracy
The aim of this project is to provide an empirical and theoretical re-conceptualization of political parties and party democracy. The challenge of democratic legitimacy faced by political parties in modern democracies derives principally from their deteriorating relationship with society, which has been accentuated by ...
[ "Institutions, Governance and Legal Systems", "The Social World and Its Interactions" ]
10.1007/s10519-013-9610-1
Association between autozygosity and major depression: Stratification due to religious assortment
The effects of inbreeding on the health of offspring can be studied by measuring genome-wide autozygosity as the proportion of the genome in runs of homozygosity (F roh) and relate F roh to outcomes such as psychiatric phenotypes. To successfully conduct these studies, the main patterns of variation for genome-wide aut...
[ "Integrative Biology: from Genes and Genomes to Systems", "The Social World and Its Interactions" ]