id stringlengths 6 42 | title stringlengths 3 499 | abstract stringlengths 0 6.24k | label listlengths 0 6 |
|---|---|---|---|
CZ 2015000058 W | A STABILIZED FORMULATION OF FESOTERODINE | The present invention relates to a stable pharmaceutical formulation, containing fesoterodine [2-[(1R)-3-(Di(propan-2-yl)amino)-1-phenylpropyl]-4- (hydroxymethyl)phenyl] 2-methyl propanoate of formula (I) and/or its salts, solvate ester and a method of its preparation. (Formula (I)) | [
"Synthetic Chemistry and Materials",
"Products and Processes Engineering"
] |
10.1039/c6ja00064a | Ultra-high-precision Nd-isotope measurements of geological materials by MC-ICPMS | We report novel techniques allowing the measurement of Nd-isotope ratios with unprecedented accuracy and precision by multi-collector inductively coupled plasma mass spectrometry. | [
"Physical and Analytical Chemical Sciences",
"Earth System Science"
] |
10.1038/ncomms15869 | Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis | Somatic mutations contribute to tumorigenesis. Although these mutations occur in all proliferating cells, their accumulation under non-malignant conditions, such as in autoimmune disorders, has not been investigated. Here, we show that patients with newly diagnosed rheumatoid arthritis have expanded CD8+ T-cell clones;... | [
"Immunity, Infection and Immunotherapy",
"Integrative Biology: from Genes and Genomes to Systems",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
337128 | The Archaeology of Agricultural Resilience in Eastern Africa | The twin concepts of sustainability and conservation that are so pivotal within current debates regarding economic development and biodiversity protection both contain an inherent temporal dimension, since both refer to the need to balance short-term gains with long-term resource maintenance. Proponents of resilience t... | [
"The Study of the Human Past",
"Environmental Biology, Ecology and Evolution",
"Earth System Science"
] |
10.5194/acp-19-11765-2019 | In situ constraints on the vertical distribution of global aerosol | Abstract. Despite ongoing efforts, the vertical distribution of aerosols globally is
poorly understood. This in turn leads to large uncertainties in the
contributions of the direct and indirect aerosol forcing on climate. Using
the Global Aerosol Synthesis and Science Project (GASSP) database – the
largest synthesised ... | [
"Earth System Science",
"Physical and Analytical Chemical Sciences"
] |
W1982382928 | Competition Between Viscoelasticity and Surfactant Dynamics in Flow Focusing Microfluidics | The goal of this work is to quantify the impact of viscoelasticity on a tipstreaming phenomenon observed in flow focusing microfluidic devices. Tipstreaming, or thread formation, is a phenomenon caused by surfactant transport to, from, and along, deforming interfaces that leads to long filaments in microfluidic devices... | [
"Physical and Analytical Chemical Sciences",
"Condensed Matter Physics"
] |
10.1111/arcm.12063 | Trace element analysis in provenancing Roman glass-making | In this study, the use of trace elements as a provenance indicator for Roman natron glass is evaluated. Suitable glass-making sand raw materials are analysed for their trace elemental composition and compared to glass from known production centres. It is shown that the combined use of Nd isotopic and trace element anal... | [
"Physical and Analytical Chemical Sciences",
"Materials Engineering",
"The Study of the Human Past"
] |
882990 | European e-infrastructure for extreme data analytics in sustainable development | Agriculture is a, literally, vital industry. Not only important for nourishment, but also a key determiant of health, economic and political stability; employment; business and biological ecosystems; and society. Because of its importance, most attention focuses on productivity but it is essential to have a global view... | [
"Earth System Science",
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
EP 2009061521 W | WASTE HEAT STEAM GENERATOR | The invention relates to a waste heat steam generator (1) having a plurality of evaporator tubes (4) which are connected in parallel on the flow medium side, a plurality of overheating tubes (26) being mounted downstream of the evaporator tubes by means of a water separation system. Said water separation system compris... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
W2884045397 | Orchestrating cells on a chip: Employing surface acoustic waves towards the formation of neural networks | For the investigation of cell-cell interaction in general and for neural communication and future applications of neural networks, a controllable and well-defined network structure is crucial. We here propose the implementation of an acoustically driven system for tunable and deliberate stimulation and manipulation of ... | [
"Condensed Matter Physics",
"Neuroscience and Disorders of the Nervous System",
"Systems and Communication Engineering"
] |
10.1145/3358220 | Fpga Stream Monitoring Of Real Time Properties | An essential part of cyber-physical systems is the online evaluation of real-time data streams. Especially in systems that are intrinsically safety-critical, a dedicated monitoring component inspecting data streams to detect problems at runtime greatly increases the confidence in a safe execution. Such a monitor needs ... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
670645 | A multi-resolution theory for systems and control across scales | The multi-resolution approach to science and engineering is key to tackle the complexity of systems that span across many temporal and spatial scales. This approach has revolutionized signal processing over the last two decades, most notably through wavelet theory, which builds upon the elementary concept of zooming in... | [
"Systems and Communication Engineering",
"Mathematics",
"Neuroscience and Disorders of the Nervous System"
] |
10.1056/NEJMoa1514762 | Early versus Late parenteral nutrition in critically ill children | BACKGROUND: Recent trials have questioned the benefit of early parenteral nutrition in adults. The effect of early parenteral nutrition on clinical outcomes in critically ill children is unclear. METHODS: We conducted a multicenter, randomized, controlled trial involving 1440 critically ill children to investigate whet... | [
"Physiology in Health, Disease and Ageing",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1145/3173574.3174220 | Observations On Typing From 136 Million Keystrokes | We report on typing behaviour and performance of 168,000 volunteers in an online study. The large dataset allows detailed statistical analyses of keystroking patterns, linking them to typing performance. Besides reporting distributions and confirming some earlier findings, we report two new findings. First, letter pair... | [
"Computer Science and Informatics"
] |
10.1002/ijc.28945 | Lung tumours reprogram pulmonary Dendritic cell immunogenicity at the microrna level | Lung cancer arises in a context of tumour-induced immune suppression. Dendritic cells (DCs) are central players in the induction of anti-tumoural immunity, providing critical signals that drive the induction of cytotoxic T-cell responses. Meanwhile, microRNAs are associated with tumour development as well as immune reg... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
W1780936642 | Glitazones are associated with reduced risk of COPD exacerbations and mortality among patients with diabetes | Introduction: Moderators of systemic inflammation may reduce risk of exacerbations among patients with COPD. Glitazones, used in the treatment of diabetes, also have anti-inflammatory properties. We sought to assess whether glitazones were associated with a decreased risk of COPD exacerbations and mortality. Study desi... | [
"Physiology in Health, Disease and Ageing",
"Immunity, Infection and Immunotherapy"
] |
W4281839841 | Banco Comunitário Moeda Verde: uma proposta de ressignicação dos resíduos sólidos na Amazônia | A problemática da gestão de resíduos sólidos municipais é um desafio para administração pública, pois se trata de um espaço bastante complexo onde se confrontam interesses, havendo a necessidade de se pensar soluções criativas com diversidade de campos de influência; aumentar possibilidades para alternativas de inovaçã... | [
"Environmental Biology, Ecology and Evolution",
"Human Mobility, Environment, and Space",
"Products and Processes Engineering"
] |
W1985616978 | Asymmetric Synthesis of α-Amino-1,3-dithianes via Chiral <i>N</i>-Phosphonyl Imine-Based Umpolung Reaction Without Using Chromatography and Recrystallization | A series of α-amino-1,3-dithianes have been synthesized via the asymmetric Umpolung reaction of 2-lithio-1,3-dithianes with chiral N-phosphonyl imines in good chemical yields (up to 82%) and good to excellent diastereoselectivities (>99:1). The manner by which chiral N-phosphonyl imines are slowly added into the soluti... | [
"Synthetic Chemistry and Materials",
"Physical and Analytical Chemical Sciences"
] |
218043 | A handheld, ultra-sensitive device for rapid contactless explosive vapour detection in open air, based on ion mobility universal sensor technology | Explosives detection currently represents the biggest security challenge, being easy to acquire with limited resources and difficult to be detected in real-time. Recommended procedures for explosive detection are inherently unsafe: due to current technological limitations, EU regulations only prescribe screenings on a ... | [
"Products and Processes Engineering",
"Physical and Analytical Chemical Sciences",
"Systems and Communication Engineering"
] |
W3148071842 | Design and Analysis of a Novel Parallel Metamorphic Mechanism | 3-UPU parallel mechanisms, whose axes of hooke joint on base plate and moving plate fit different geometric constraints, can have translational or orientational output. A configuration-switch mechanism for 3-UPU parallel mechanism is designed based on the theory of metamorphic that change the orientations of kinematic ... | [
"Products and Processes Engineering",
"Systems and Communication Engineering"
] |
NL 8702306 A | Distance measuring device laser light source - has optics emitting light beam in measuring range optics projecting reflected light onto detector | The device for measuring distances has a laser light source with a first optical system with which a laser beam is emitted in the direction of a measuring range. There is also a positionally sensitive light detector and a second optical system with which light, reflected by an object in the range, is projected onto the... | [
"Systems and Communication Engineering"
] |
10.1523/JNEUROSCI.2365-14.2014 | Initial Investigation Of The Effects Of An Experimentally Learned Schema On Spatial Associative Memory In Humans | Networks of interconnected neocortical representations of prior knowledge, “schemas,” facilitate memory for congruent information. This facilitation is thought to be mediated by augmented encoding and accelerated consolidation. However, it is less clear how schema affects retrieval. Rodent and human studies to date sug... | [
"Neuroscience and Disorders of the Nervous System",
"The Human Mind and Its Complexity"
] |
10.1371/journal.pntd.0003847 | Genotypic diversity is associated with clinical outcome and phenotype in cryptococcal meningitis across Southern Africa | Cryptococcal meningitis is a major cause of mortality throughout the developing world, yet little is known about the genetic markers underlying Cryptococcal virulence and patient outcome. We studied a cohort of 230 Cryptococcus neoformans (Cn) isolates from HIV-positive South African clinical trial patients with detail... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1016/j.chom.2015.10.015 | Autophagy proteins promote repair of endosomal membranes damaged by the Salmonella type three secretion system 1 | Salmonella Typhimurium (S. Tm) is an enteropathogen requiring multiple virulence factors, including two type three secretion systems (T1 and T2). T1 triggers epithelium invasion in which the bacteria are taken up into endosomes that mature into Salmonella-containing vacuoles (SCV) and trigger T2 induction upon acidific... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Immunity, Infection and Immunotherapy"
] |
228304 | Equidistribution in number theory | The purpose of this proposal is to investigate from various perspectives some equidistribution problems associated with homogeneous spaces of arithmetic type: a typical problem (basically solved) is the distribution of the set of representations of a large integer by an integral quadratic form. Another harder problem i... | [
"Mathematics"
] |
10.1098/rspa.2014.0232 | An elastica arm scale | The concept of a ‘deformable arm scale’ (completely different from a traditional rigid arm balance) is theoretically introduced and experimentally validated. The idea is not intuitive, but is the result of nonlinear equilibrium kinematics of rods inducing configurational forces, so that deflection of the arms becomes n... | [
"Condensed Matter Physics",
"Materials Engineering"
] |
10.1111/jnc.13044 | Opposite control of frontocortical 2-arachidonoylglycerol turnover rate by cannabinoid type-1 receptors located on glutamatergic neurons and on astrocytes | This study examined the respective influences of cannabinoid type-1 (CB<inf>1</inf>) receptors expressed either in forebrain GABAergic neurons, in cortical glutamatergic neurons, or in astrocytes on the turnover rates of the endocannabinoids N-arachidonoylethanolamide (AEA) and 2-arachidonoylglycerol (2-AG), and the no... | [
"Neuroscience and Disorders of the Nervous System",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1515/9783110614404-016 | The Distinctiveness Of Syntax For Varieties Of Post Classical And Byzantine Greek Linguistic Upgrading From The Third Century Bce To The Tenth Century Ce | Specialists of the history of Ancient Greek scholarship and modern-day sociolinguists alike have made observations regarding the seemingly “distinctive” status of syntax: the former have argued there is no coherent theory of syntax in Ancient grammatical treatises, and the latter that syntactic variation is much less p... | [
"Texts and Concepts",
"The Study of the Human Past",
"The Human Mind and Its Complexity"
] |
10.1080/13629387.2013.862775 | Integrating the Medieval Iberian Peninsula and North Africa in Islamic Architectural History | How do Islamic art survey texts present the architecture of the Islamic West, and how does this presentation shape the perception of the Maghrib in university classrooms? Examining the Great Mosque of Qayrawān and the Great Mosque of Cordoba as they appear in four representative and widely used art history survey texts... | [
"Texts and Concepts",
"The Study of the Human Past",
"Studies of Cultures and Arts"
] |
10.1371/journal.pcbi.1003508 | Dynamic Alignment Models for Neural Coding | Recently, there have been remarkable advances in modeling the relationships between the sensory environment, neuronal responses, and behavior. However, most models cannot encompass variable stimulus-response relationships such as varying response latencies and state or context dependence of the neural code. Here, we co... | [
"Neuroscience and Disorders of the Nervous System",
"Computer Science and Informatics"
] |
10.7717/peerj.2707 | Dominance relationships in a family pack of captive arctic wolves (Canis lupus arctos): The influence of competition for food, age and sex | Background. Dominance is one of the most pervasive concepts in the study of wolf social behaviour but recently its validity has been questioned. For some authors, the bonds between members of wolf families are better described as parent-offspring relationships and the concept of dominance should be used just to evaluat... | [
"Environmental Biology, Ecology and Evolution",
"The Social World and Its Interactions"
] |
W1985702957 | Layer-by-layer structured polysaccharides film-coated cellulose nanofibrous mats for cell culture | Abstract For the first time, a novel fibrous polysaccharide scaffold for cell culture was fabricated by the combination of electrospinning and electrostatic layer-by-layer (LBL) self-assembly technique. Oppositely charged chitosan (CS) and alginate (ALG) in aqueous media were alternatively deposited onto the negatively... | [
"Materials Engineering",
"Synthetic Chemistry and Materials",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
222993 | Manufacturing ecosystem of qualified resources exchange | The MANU-SQUARE project creates a European platform-enabled responsible ecosystem acting as a virtual marketplace, bringing available manufacturing capacity closer to production demand to achieve their optimal matching thus fostering, on the one hand, fast and efficient creation of local and distributed value networks ... | [
"Products and Processes Engineering",
"Computer Science and Informatics"
] |
Q2701807 | BP CYCLADES-GRANT FOR WORKING CAPITAL | The project concerns support for working capital of a company in the event of a decline in turnover (sales revenue) caused by the negative effects of the COVID-19 outbreak. | [
"Individuals, Markets and Organisations"
] |
W2906171482 | Research on Wind & Thermal Power Joint Bidding Strategy Considering Penalties for Wind Power's Bidding Deviation | With the growing maturity of wind power technologies and the decrease of wind power construction costs, wind power producers, who are always price takers, gradually become the market participants with strategic bidding capacity in electricity market. However, wind power producers should be responsible for the loss caus... | [
"Systems and Communication Engineering",
"Products and Processes Engineering",
"Individuals, Markets and Organisations"
] |
758448 | Insular cortical circuits controlling fear and anxiety | How do emotions guide our behaviour? For an appropriate behavioural response, an individual has to constantly integrate bodily feelings, emotional states, and cues from the environment to evaluate the risks and benefits of a future action. A growing body of evidence indicates that the insular cortex, as part of a distr... | [
"Neuroscience and Disorders of the Nervous System",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
W2112141492 | A Rapid Automatic Processing Platform for Bead Label–Assisted Microarray Analysis | Molecular diagnostics using microarrays are increasingly being used in clinical diagnosis because of their high throughput, sensitivity, and accuracy. However, standard microarray processing takes several hours and involves manual steps during hybridization, slide clean up, and imaging. Here we describe the development... | [
"Products and Processes Engineering",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1142/S0219199717500286 | Matrix Regularizing Effects Of Gaussian Perturbations | The addition of noise has a regularizing effect on Hermitian matrices. This effect is studied here for H = A + V, where A is the base matrix and V is sampled from the GOE or the GUE random matrix ensembles. We bound the mean number of eigenvalues of H in an interval, and present tail bounds for the distribution of the ... | [
"Mathematics"
] |
W2916603812 | Relation between Labour Productivity and Export Competitiveness of Indian Textile Industry: Co-integration and Causality Approach | The most important factor impacting the export competitiveness (EC) of an industry is productivity trends. One such significant variable of productivity can be labour productivity (LP). The purpose of this article is to examine the relationship between LP and EC for the Indian textile industry in the post-liberalizatio... | [
"Individuals, Markets and Organisations"
] |
695206 | Building tomorrow’s nanofactory | The aim of this project is to translate the concept of production line to the nanoworld to develop what could become tomorrow’s nanofactory. So far, nanostructures are either chemically synthesized or produced using top-down approaches such as nanolithography, but no processes exist to take a few nanostructures and per... | [
"Physical and Analytical Chemical Sciences",
"Condensed Matter Physics",
"Materials Engineering"
] |
10.1007/jhep09(2020)185 | Topological correlators and surface defects from equivariant cohomology | Abstract
We find a one-dimensional protected subsector of $$ \mathcal{N} $$
N
= 4 matter theories on a general class of three-dimensional manifolds. By means of equivariant localization we identify a dual quantum mechanics computing BPS correlators of the original model in three dimensions. Specifically, applying the ... | [
"Fundamental Constituents of Matter",
"Mathematics"
] |
10.1002/chem.201601670 | The Catalytic Mechanism of the Marine-Derived Macrocyclase PatGmac | Cyclic peptides are a class of compounds with high therapeutic potential, possessing bioactivities including antitumor and antiviral (including anti-HIV). Despite their desirability, efficient design and production of these compounds has not been achieved to date. The catalytic mechanism of patellamide macrocyclization... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
W2077840270 | Provisioning of QoS adaptability in wired-wireless integrated networks | The increasing number of mobile users and the popularity of real-time applications make wired-wireless integrated network extremely attractive. In this case, quality of service (QoS) adaptability is particularly important since some important features of the integrated network call for QoS adaptability, such as mobilit... | [
"Systems and Communication Engineering",
"Computer Science and Informatics"
] |
10.1051/0004-6361/201731877 | Ionised gas structure of 100 kpc in an over-dense region of the galaxy group COSMOS-Gr30 at z ~ 0.7 | We report the discovery of a 104 kpc2 gaseous structure detected in [O ii]λλ3727, 3729 in an over-dense region of the COSMOS-Gr30 galaxy group at z ~ 0. 725 with deep MUSE Guaranteed Time Observations. We estimate the total amount of diffuse ionised gas to be of the order of (~5 ± 3) × 1010 M⊙ and explore its physical ... | [
"Universe Sciences",
"Physical and Analytical Chemical Sciences"
] |
10.1145/2610384.2628058 | Corebench Studying Complexity Of Regression Errors | Intuitively we know, some software errors are more complex than others. If the error can be fixed by changing one faulty statement, it is a simple error. The more substantial the fix must be, the more complex we consider the error. In this work, we formally define and quantify the complexity of an error w. r. t. the c... | [
"Computer Science and Informatics"
] |
10.1007/978-3-319-18585-9_11 | Martingale Inequalities For The Maximum Via Pathwise Arguments | We study a class of martingale inequalities involving the running maximum process. They are derived from pathwise inequalities introduced by Henry-Labordere et al. (Ann. Appl. Probab. , 2015 [arxiv:1203. 6877v3]) and provide an upper bound on the expectation of a function of the running maximum in terms of marginal dis... | [
"Mathematics"
] |
10.1109/CDC.2017.8263745 | On Inverse Optimal Control Via Polynomial Optimization | We consider the class of control systems where the differential equation, state and control system are described by polynomials. Given a set of trajectories and a class of Lagrangians, we are interested to find a Lagrangian in this class for which these trajectories are optimal. To model this inverse problem we use a r... | [
"Mathematics",
"Systems and Communication Engineering"
] |
10.1111/acel.12025 | A metabolic signature predicts biological age in mice | Our understanding of the mechanisms by which aging is produced is still very limited. Here, we have determined the sera metabolite profile of 117 wild-type mice of different genetic backgrounds ranging from 8 to 129 weeks of age. This has allowed us to define a robust metabolomic signature and a derived metabolomic sco... | [
"Physiology in Health, Disease and Ageing",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1038/srep40248 | A fibrolytic potential in the human ileum mucosal microbiota revealed by functional metagenomic | The digestion of dietary fibers is a major function of the human intestinal microbiota. So far this function has been attributed to the microorganisms inhabiting the colon, and many studies have focused on this distal part of the gastrointestinal tract using easily accessible fecal material. However, microbial fermenta... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Environmental Biology, Ecology and Evolution"
] |
10.1093/jxb/ers262 | Microbial recognition and evasion of host immunity | Plants are able to detect microbes by pattern recognition receptors in the host cells that, upon recognition of the enemy, activate effective immune responses in the invaded tissue. Recognition of microbes occurs by common conserved structures called microbe-associated molecular patterns (MAMPs). Plant pathogens and be... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1021/acs.langmuir.5b03316 | Electrodeposition and Screening of Photoelectrochemical Activity in Conjugated Polymers Using Scanning Electrochemical Cell Microscopy | A number of renewable energy systems require an understanding and correlation of material properties and photoelectrochemical activity on the micro to nanoscale. Among these, conducting polymer electrodes continue to be important materials. In this contribution, an ultrasensitive scanning electrochemical cell microscop... | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
W1499288673 | Metrological approaches to organic chemical purity: primary reference materials for vitamin D metabolites | Given the critical role of pure, organic compound primary reference standards used to characterize and certify chemical Certified Reference Materials (CRMs), it is essential that associated mass purity assessments be fit-for-purpose, represented by an appropriate uncertainty interval, and metrologically sound. The mass... | [
"Physical and Analytical Chemical Sciences"
] |
949173 | Role of extreme events in Galaxy evolution | The primary goal of my proposal is to provide stringent observational constraints on the cosmic origins of elements heavier than iron and on the role of extreme objects in the evolution of the Milky Way. I will do this by employing abundances of different chemical elements for hundreds of thousands of stars from my hig... | [
"Universe Sciences",
"Physical and Analytical Chemical Sciences"
] |
10.1038/s41467-018-06513-6 | A sustained change in the supply of parental care causes adaptive evolution of offspring morphology | Although cooperative social interactions within species are considered an important driver of evolutionary change, few studies have experimentally demonstrated that they cause adaptive evolution. Here we address this problem by studying the burying beetle Nicrophorus vespilloides. In this species, parents and larvae wo... | [
"Environmental Biology, Ecology and Evolution",
"Integrative Biology: from Genes and Genomes to Systems"
] |
725422 | The evolutionary dynamics of pathogen emergence and establishment: from Reservoir Detection to Outbreak Control | Extracted evolutionary and epidemiological information from pathogen genomes has grown into an important instrument across infectious disease research. By harnessing such information, molecular epidemiologists aim to shed light on the origin and epidemic history of pathogens, from reservoir dynamics to emergence and ad... | [
"Immunity, Infection and Immunotherapy",
"Integrative Biology: from Genes and Genomes to Systems",
"Prevention, Diagnosis and Treatment of Human Diseases",
"Environmental Biology, Ecology and Evolution"
] |
223737 | Comic motifs in romances of chivalry of spanish golden age | Romances of chivalry are one of the most representative literary genres of Spanish Golden Age,
which gained great popularity in XVI century. In the last few years, critical studies have stressed the
importance of the uniformity of this corpus, which includes many imitations, sequels, and prequels resuming
the threads o... | [
"Texts and Concepts",
"The Study of the Human Past"
] |
W2334361602 | Terrestrial Animal- and Plant-Based Ingredients as Alternative Protein and Lipid Sources in the Diets for Juvenile Groupers: Current Status and Future Perspectives | The Epinephelinae groupers are strict carnivorous species. They are widely cultured in the Asia Pacific region as a result of high demand and market price especially in the live reed food fish trade. Groupers are commonly raised in net cages and fed with the unsustainable low value fish. Although this feeding practice ... | [
"Biotechnology and Biosystems Engineering",
"Environmental Biology, Ecology and Evolution",
"Physiology in Health, Disease and Ageing"
] |
10.5210/fm.v24i4.9934 | The politics of big borders: Data (in)justice and the governance of refugees | This article provides an overview of the collection and uses of data in relation to European border regimes. We analyse the significance of these developments for the governance of refugee populations and make the case that within the current policy context of European border control, data functions to systematically s... | [
"Institutions, Governance and Legal Systems",
"The Social World and Its Interactions",
"Human Mobility, Environment, and Space"
] |
10.1016/j.chom.2015.09.001 | Pathogen Virulence Impedes Mutualist-Mediated Enhancement of Host Juvenile Growth via Inhibition of Protein Digestion | Summary The microbial environment impacts many aspects of metazoan physiology through largely undefined molecular mechanisms. The commensal strain Lactobacillus plantarumWJL (LpWJL) sustains Drosophila hormonal signals that coordinate systemic growth and maturation of the fly. Here we examine the underlying mechanisms ... | [
"Immunity, Infection and Immunotherapy",
"Physiology in Health, Disease and Ageing",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
887266 | A platform to boost robotic innovation by enabling fast development cycles, reduced cost and low barrier to entry. | Our vision is to make robotic product development as accessible as online publishing is today. Our aim is to power the social and personal robotic revolution.
Today robotic companies have vertical models, they source, conceive, build, mass produce and distribute their own robots. This is a high cost and high risk ende... | [
"Computer Science and Informatics",
"Products and Processes Engineering",
"Systems and Communication Engineering"
] |
10.1681/ASN.2015070830 | The uromodulin gene locus shows evidence of pathogen adaptation through human evolution | Common variants in the UMOD gene encoding uromodulin, associated with risk of hypertension and CKD in the general population, increase UMOD expression and urinary excretion of uromodulin, causing salt-sensitive hypertension and renal lesions. To determine the effect of selective pressure on variant frequency, we invest... | [
"Integrative Biology: from Genes and Genomes to Systems",
"Environmental Biology, Ecology and Evolution",
"Immunity, Infection and Immunotherapy"
] |
10.1016/j.ophtha.2017.12.023 | Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation: Implications in Age-Related Macular Degeneration | Purpose: To identify genetic variants associated with complement activation, which may help to select age-related macular degeneration (AMD) patients for complement-inhibiting therapies. Design: Genome-wide association study (GWAS) followed by replication and meta-analysis. Participants: AMD patients and controls (n = ... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1126/science.aau4963 | Probing Rényi entanglement entropy via randomized measurements | Entanglement is a key feature of many-body quantum systems. Measuring the entropy of different partitions of a quantum system provides a way to probe its entanglement structure. Here, we present and experimentally demonstrate a protocol for measuring the second-order Rényi entropy based on statistical correlations betw... | [
"Fundamental Constituents of Matter",
"Condensed Matter Physics"
] |
10.1002/anie.201814370 | Electrocatalytic Volleyball: Rapid Nanoconfined Nicotinamide Cycling for Organic Synthesis in Electrode Pores | In living cells, redox chains rely on nanoconfinement using tiny enclosures, such as the mitochondrial matrix or chloroplast stroma, to concentrate enzymes and limit distances that nicotinamide cofactors and other metabolites must diffuse. In a chemical analogue exploiting this principle, nicotinamide adenine dinucleot... | [
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1051/0004-6361/201424517 | Interpreting The Extended Emission Around Three Nearby Debris Disc Host Stars | Context. Cool debris discs are a relic of the planetesimal formation process around their host star, analogous to the solar system’s Edgeworth-Kuiper belt. As such, they can be used as a proxy to probe the origin and formation of planetary systems like our own. Aims. The Herschel open time key programmes “DUst around N... | [
"Universe Sciences",
"Physical and Analytical Chemical Sciences"
] |
10.1007/978-3-642-40760-4_34 | Joint Model Pixel Segmentation With Pose Invariant Deformable Graph Priors | This paper proposes a novel framework for image segmentation through a unified model-based and pixel-driven integrated graphical model. Prior knowledge is expressed through the deformation of a discrete model that consists of decomposing the shape of interest into a set of higher order cliques (triplets). Such decompos... | [
"Computer Science and Informatics",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
Q4426997 | Diversification of the activities of FOXBUY.COM Spółka Akcyjna by launching the production of innovative cosmetics for children | The project consists of launching the production of innovative cosmetics for children. Before starting production, it is necessary to: construction of a production hall and purchase of a technological line for the production of innovative products with auxiliary equipment. The implementation phases of the project are p... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
EP 2007053083 W | CELL SENSOR HAVING MULTIFUNCTIONAL REACTIONS FOR THE DEFINITION OF QUALITY CRITERIA DURING THE PRODUCTION OF MATERIALS | Disclosed is a method for producing a cell sensor system used for defining quality criteria during the production of materials. Said method is characterized by the following steps: a) first cells of a specific type are cultivated in standard culture conditions (control group); b) second cells of said specific type are ... | [
"Materials Engineering",
"Cell Biology, Development, Stem Cells and Regeneration",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1021/acs.nanolett.5b02885 | Single-crystal diamond nanowire tips for ultrasensitive force microscopy | We report the fabrication, integration, and assessment of sharp diamond tips for ultrasensitive force microscopy experiments. Two types of tips, corresponding to the upper and lower halves of a diamond nanowire, were fabricated by top-down plasma etching from a single-crystalline substrate. The lower, surface-attached ... | [
"Condensed Matter Physics",
"Materials Engineering",
"Physical and Analytical Chemical Sciences"
] |
US 2012/0036932 W | THERMOSTABLE CARBONIC ANHYDRASES AND METHODS OF USE THEREOF | The present compositions and methods relate to a thermostable carbonic anhydrases, polynucleotides encoding the carbonic anhydrase, and methods of make and/or use thereof. Formulations containing the carbonic anhydrase are suitable for use in extracting carbon dioxide. | [
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
W1579144193 | Vesselness-guided Active Contour: A Coronary Vessel Extraction Method | Vessel extraction is a critical task in clinical practice. In this paper, we propose a new approach for vessel extraction using an active contour model by defining a novel vesselness-based term, based on accurate analysis of the vessel structure in the image. To achieve the novel term, a simple and fast directional fil... | [
"Systems and Communication Engineering",
"Computer Science and Informatics"
] |
US 0313039 W | THERMALLY-ACTIVATED ACTUATOR | An actuator having a hot-arm and a cold-arm wherein the hot-arm and cold-arm vertically offset from one another. The hot-arm is heated to cause the actuator to move both vertically and horizontally. When used as a relay, an electrostatic force latches the actuator when the electrodes are brought in close proximity to o... | [
"Products and Processes Engineering",
"Systems and Communication Engineering"
] |
10.1177/0271678X16656864 | Quantitative T1 mapping under precisely controlled graded hyperoxia at 7T | Increasing the concentration of oxygen dissolved in water is known to increase the recovery rate (R1 = 1/T1) of longitudinal magnetization (T1 relaxation). Direct T1 changes in response to precise hyperoxic gas challenges have not yet been quantified and the actual effect of increasing arterial oxygen concentration on ... | [
"Physical and Analytical Chemical Sciences",
"Condensed Matter Physics",
"Neuroscience and Disorders of the Nervous System",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1145/3132272.3135088 | Personalized Interactive Surfaces With Printed Electronics | Recent advances in printed electronics have enabled the design and fabrication of thin, flexible and customizable interactive surfaces. These interfaces create opportunities for a variety of novel interactions leveraging on the unique form factor, flexibility and customization options. Previous research has demonstrate... | [
"Systems and Communication Engineering",
"Materials Engineering"
] |
10.1016/j.stem.2020.01.002 | Defining the Adult Neural Stem Cell Niche Proteome Identifies Key Regulators of Adult Neurogenesis | The physical properties of stem cell niches are thought to mediate important regulatory functions. Here we provide a proteomic resource of the neural stem cell niche in comparison to gliogenic brain parenchyma, highlighting stiffness and the enzyme transglutaminase 2 as key regulators of neurogenesis. | [
"Neuroscience and Disorders of the Nervous System",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
W1498306344 | O lugar do Sistema Mineiro de Avaliação da Educação Pública (Simave) na busca pela qualidade da educação no Brasil | The Mining System for Evaluation of Public Education (Simave), responsible for the development of integrated assessment of education in the state of Minas Gerais, emerges in the wake of implementation of regulatory policy of education in Brazil. This policy, in turn, is part of the reform movement of educational polici... | [
"The Social World and Its Interactions",
"Institutions, Governance and Legal Systems"
] |
628850 | Recycling shredded used tyres and rubber waste into personalized recovered carbon black to limit use of fossil fuels and carbon dioxide emission | Rubber tyres have been with us for the last 130 years. Manufactured and used on a massive scale, they have a significant impact on our economy. But they also generate global problems related to handling of over 1.5 billion of used tyres every year, and consuming fossil fuels (mostly crude oil) to produce new ones. Only... | [
"Products and Processes Engineering",
"Environmental Biology, Ecology and Evolution",
"Materials Engineering"
] |
W2038431427 | Comparison of 6th and 7th AJCC TNM Staging Classification for Carcinoma of the Stomach in China | The 7th edition of American Joint Committee on Cancer tumor-node-metastasis (AJCC TNM) staging system was put into use recently. The study aimed to evaluate its predictive ability on survival and compare the difference between the 6th and 7th editions of AJCC TNM system in gastric carcinoma.A total of 1000 gastric carc... | [
"Prevention, Diagnosis and Treatment of Human Diseases",
"Physiology in Health, Disease and Ageing"
] |
10.1038/nature08798 | Antagonistic coevolution accelerates molecular evolution | The Red Queen hypothesis proposes that coevolution of interacting species (such as hosts and parasites) should drive molecular evolution through continual natural selection for adaptation and counter-adaptation. Although the divergence observed at some host-resistance and parasite-infectivity genes is consistent with t... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Environmental Biology, Ecology and Evolution"
] |
W2107455682 | The role of pitch and temporal diversity in the perception and production of musical sequences | In two experiments we explored how the dimensions of pitch and time contribute to the perception and production of musical sequences. We tested how dimensional diversity (the number of unique categories in each dimension) affects how pitch and time combine. In Experiment 1, 18 musically trained participants rated the c... | [
"The Human Mind and Its Complexity"
] |
W2056185024 | Career Adapt-Abilities Scale–Short Form (CAAS-SF) | The Career Adapt-Abilities Scale (CAAS) has become one of the most widely used questionnaires to assess career adaptability. To facilitate its integration into large surveys, in varied settings, the aim of this article was to develop a brief 12-item version, the Career Adapt-Abilities Scale–Short Form (CAAS-SF). A samp... | [
"The Human Mind and Its Complexity",
"The Social World and Its Interactions"
] |
10.1002/grl.50447 | Azimuthal anisotropy at Valhall: The Helmholtz equation approach | We used 6 h of continuous vertical records from 2320 sensors of the Valhall Life of Fields Seismic network to compute 2,690,040 cross-correlation functions between the full set of sensor pair combinations. We applied the "Helmholtz tomography" approach combined with the ambient noise correlation method to track the wav... | [
"Condensed Matter Physics",
"Earth System Science"
] |
10.1113/JP272791 | Convergence of visual and whisker responses in the primary somatosensory thalamus (ventral posterior medial region) of the mouse | Key points: Using in vivo electrophysiology, we find that a subset of whisker-responsive neurons in the ventral posterior medial region (VPM) respond to visual stimuli. These light-responsive neurons in the VPM are particularly sensitive to optic flow. Presentation of optic flow stimuli modulates the amplitude of concu... | [
"Neuroscience and Disorders of the Nervous System"
] |
10.1074/jbc.M114.621789 | Complex structure and biochemical characterization of the Staphylococcus aureus cyclic diadenylate monophosphate (c-di-AMP)-binding protein PstA, the founding member of a new signal transduction protein family | Signaling nucleotides are integral parts of signal transduction systems allowing bacteria to cope with and rapidly respond to changes in the environment. The Staphylococcus aureus PII-like signal transduction protein PstA was recently identified as a cyclic diadenylate monophosphate (c-di-AMP)-binding protein. Here, we... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems"
] |
324202 | The Milking Revolution in Temperate Neolithic Europe | This project explores the introduction and spread of cattle-based agriculture by Neolithic Linearbandkeramik (LBK) farmers and its implications for modelling of the Mesolithic-Neolithic transition in Northern and Central Europe beginning ca. 8,000 years ago. This revolutionary shift in human subsistence strategy comple... | [
"The Study of the Human Past",
"Environmental Biology, Ecology and Evolution",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems"
] |
221358 | Multifunctionnal cabin rest area | Airbus has defined the need for a multi-functional cabin rest area, under JTI-CS2-2016-CFP04-AIR-01-24 Program Area AIR – WP A-5.1.1. Zodiac answers to this call with project CRiSTA (Cabin ReST Area). Zodiac has an excellent track record in cabin concepts, crew rests and galleys (almost 90% market share of galleys in ... | [
"Products and Processes Engineering",
"Systems and Communication Engineering",
"Materials Engineering"
] |
10.1038/ncomms11126 | Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering | Sleeping Beauty (SB) is a prominent Tc1/mariner superfamily DNA transposon that provides a popular genome engineering tool in a broad range of organisms. It is mobilized by a transposase enzyme that catalyses DNA cleavage and integration at short specific sequences at the transposon ends. To facilitate SB's application... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Biotechnology and Biosystems Engineering"
] |
637503 | High precision isotopic measurements of heavy elements in extra-terrestrial materials: origin and age of the solar system volatile element depletion | The objectives of this proposal, PRISTINE (high PRecision ISotopic measurements of heavy elements in extra-Terrestrial materials: origIN and age of the solar system volatile Element depletion), are to develop new cutting edge high precision isotopic measurements to understand the origin of the Earth, Moon and solar sys... | [
"Physical and Analytical Chemical Sciences",
"Universe Sciences",
"Earth System Science"
] |
10.1142/S0217751X17500208 | Implications Of Diphoton Searches For A Radion In The Bulk Higgs Scenario | In this work we point out that the apparent diphoton excess initially presented by the ATLAS and CMS collaborations could have originated from a radion in the bulk Higgs scenario within a warped extra dimension. In this scenario the couplings of the radion to massive gauge bosons are suppressed, allowing it to evade ex... | [
"Fundamental Constituents of Matter"
] |
10.1063/1.4818878 | Ultrafast Coherent Control Of Giant Oscillating Molecular Dipoles In The Presence Of Static Electric Fields | We propose a scheme to generate electric dipole moments in homonuclear molecular cations by creating, with an ultrashort pump pulse, a quantum superposition of vibrational states on electronic states strongly perturbed by very strong static electric fields. By field-induced molecular stabilization, the dipoles can reac... | [
"Physical and Analytical Chemical Sciences",
"Fundamental Constituents of Matter"
] |
10.1109/INES.2016.7555125 | Control Engineering Approaches At Obuda University For Physiological Problems | Medical devices and computerized medical applications are exponentially increasing nowadays. This is actively supported by the EU's personalized healthcare m-Health and e-Health research programs. The core of such researches is represented undoubtedly by the basic field of biomedical engineering, the physiological mode... | [
"Systems and Communication Engineering",
"Physiology in Health, Disease and Ageing",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
W2031379437 | Effect of boron and nitrogen doping with native point defects on the vibrational properties of graphene | Abstract Boron and nitrogen doping in graphene has important implications in graphene-based devices. We investigate systematically the vibrational properties of B- and N-doped graphene with vacancies using forced vibrational method. We have calculated the phonon density of states (PDOSs), typical mode patterns and phon... | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
W2090789248 | VisualEyes: A Modular Software System for Oculomotor Experimentation | Eye movement studies have provided a strong foundation forming an understanding of how the brain acquires visual information in both the normal and dysfunctional brain.(1) However, development of a platform to stimulate and store eye movements can require substantial programming, time and costs. Many systems do not off... | [
"Computer Science and Informatics",
"Neuroscience and Disorders of the Nervous System"
] |
W2094446804 | Neoliberal Logics of Voice: Playback Singing and Public Femaleness in South India | AbstractThis essay explores the impact of neoliberal logics of voice on the music-making and performance practices of female playback singers in the South Indian Tamil film industry. As singers whose voices are first recorded in the studio and then ‘played back’ on the set to be lip-synched by actors, playback singers ... | [
"Texts and Concepts",
"The Social World and Its Interactions",
"Studies of Cultures and Arts"
] |
Q7283135 | field notes- regionale und überregionale Strahlkraft zeitgenössicher Musik aus Berlin | Das Projekt „field notes“ zielt darauf ab, die Präsenz zeitgenössischer Musik in der Öffentlichkeit zu stärken. Damit soll die Steigerung der Auslastung der Veranstaltungen und die Vernetzung der Musiker / Komponisten / weiterer Akteure des Genres Neue Musik untereinander und auch mit Zulieferern erreicht werden. Folge... | [
"Studies of Cultures and Arts",
"The Social World and Its Interactions"
] |
10.1038/nn.3532 | Membrane potential correlates of sensory perception in mouse barrel cortex | Neocortical activity can evoke sensory percepts, but the cellular mechanisms remain poorly understood. We trained mice to detect single brief whisker stimuli and report perceived stimuli by licking to obtain a reward. Pharmacological inactivation and optogenetic stimulation demonstrated a causal role for the primary so... | [
"Neuroscience and Disorders of the Nervous System",
"Physiology in Health, Disease and Ageing"
] |
10.1016/j.dnarep.2013.10.003 | The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast | DNA interstrand cross-links (ICLs) represent a physical barrier to the progression of cellular machinery involved in DNA metabolism. Thus, this type of adduct represents a serious threat to genomic stability and as such, several DNA repair pathways have evolved in both higher and lower eukaryotes to identify this type ... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1080/02626667.2016.1230674 | Adaptation Of Water Resources Systems To Changing Society And Environment A Statement By The International Association Of Hydrological Sciences | We explore how to address the challenges of adaptation of water resources systems under changing conditions by supporting flexible, resilient and low-regret solutions, coupled with on-going monitoring and evaluation. This will require improved understanding of the linkages between biophysical and social aspects in orde... | [
"Earth System Science",
"Human Mobility, Environment, and Space"
] |
US 2005/0018113 W | BEVERAGE DISPENSER WITH AUTOMATIC CUP-FILLING CONTROL | A beverage dispenser for filling a container preferably has a nozzle through which the beverage is discharged and a pivoting lever located underneath the nozzle that detects the placement of a container so as to regulate the actuation of the dispenser. A conductive probe is in line with the discharged beverage stream, ... | [
"Products and Processes Engineering",
"Systems and Communication Engineering"
] |
172729 | Europe’S lost frontiers: exploring climate change, settlement and colonisation of the submerged landscapes of the north sea basin using ancient dna, seismic mapping and complex systems modelling | The only lands on Earth that have not been explored in any depth by science are those that have been lost to the oceans. Global warming at the end of the last Ice Age led to the inundation of vast landscapes that had once been home to thousands of people. These lost lands hold a unique and largely unexplored record of ... | [
"Earth System Science",
"The Study of the Human Past",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Systems and Communication Engineering"
] |
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