id stringlengths 6 42 | title stringlengths 3 499 | abstract stringlengths 0 6.24k | label listlengths 0 6 |
|---|---|---|---|
220422 | The role of chromatin in the long-term adaptation of plants to abiotic stress | Abiotic stress is a major threat to global crop yields and this problem is likely to be exacerbated in the future. Therefore, it is very important to engineer crop plants with improved stress tolerance. A large body of research has focussed on the immediate stress responses. However, in nature stress is frequently chro... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Environmental Biology, Ecology and Evolution",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1016/j.molcel.2017.04.025 | Extending the Host Range of Bacteriophage Particles for DNA Transduction | A major limitation in using bacteriophage-based applications is their narrow host range. Approaches for extending the host range have focused primarily on lytic phages in hosts supporting their propagation rather than approaches for extending the ability of DNA transduction into phage-restrictive hosts. To extend the h... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Biotechnology and Biosystems Engineering"
] |
10.1007/jhep03(2020)154 | Off-shell vs on-shell modelling of top quarks in photon associated production | We present a comparative study of various approaches for modelling of the $$ {e}^{+}{v}_e{\mu}^{-}{\overline{v}}_{\mu }b\overline{b}\gamma $$ e + v e μ − v ¯ μ b b ¯ γ final state in $$ t\overline{t}\gamma $$ t t ¯ γ production at the LHC. Working at the NLO in QCD we compare the fully realistic description of the top ... | [
"Fundamental Constituents of Matter"
] |
interreg_686 | competivity company and innovation | "This project is part of the plan CLIP" : The CIRCUITO project aims to structure a shared cross-border programing to sustain innovation capacities of industries within ALCOTRA’s cooperation space. CIRCUITO allows a real sharing between regional authorities and structures sustaining innovation of strategies to pursue to... | [
"Computer Science and Informatics",
"Products and Processes Engineering",
"Individuals, Markets and Organisations"
] |
10.1039/C2NR30431G | Correlative Light Ion Microscopy For Biological Applications | Here we report a new technique, Correlative Light-Ion Microscopy (CLIM), to correlate SEM-like micrographs with fluorescence images. This technique presents significant advantages over conventional methods in enabling topographical and biochemical information to be correlated with nanoscale resolution without destroyin... | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
US 201314424023 A | METHOD OF OPERATING A WIND TURBINE | Method of operating a wind turbine comprising detecting when a first blade substantially approaches the shadow of the tower, and pitching at least one other blade, which is in or approaching a position above the tower, to increase the angle of attack and wind load on said at least one other blade in such a way that an ... | [
"Products and Processes Engineering",
"Systems and Communication Engineering"
] |
10.1051/0004-6361/201628913 | Impact Of Flux Distribution On Elementary Heating Events | This work used the COSMA Data Centric system at Durham University, operated by the Institute for Computational Cosmology on behalf of the STFC DiRAC HPC Facility (www. dirac. ac. uk. This equipment was funded by a BIS National E-infrastructure capital grant ST/K00042X/1, STFC capital grant ST/K00087X/1, DiRAC Operation... | [
"Universe Sciences",
"Computer Science and Informatics"
] |
10.1016/j.cub.2014.08.005 | The balance of prickle/spiny-legs isoforms controls the amount of coupling between core and fat PCP systems | Background: The conserved Fat and Core planar cell polarity (PCP) pathways work together to specify tissue-wide orientation of hairs and ridges in the Drosophila wing. Their components form intracellularly polarized complexes at adherens junctions that couple the polarity of adjacent cells and form global patterns. How... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1109/TNET.2016.2619721 | Network Coding Schemes For Data Exchange Networks With Arbitrary Transmission Delays | In this paper, we introduce construction techniques for network coding in bidirectional networks with arbitrary transmission delays. These coding schemes reduce the number of transmissions and achieve the optimal rate region in the corresponding broadcast model for both multiple unicast and multicast cases with up to t... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
10.1016/j.bspc.2017.12.007 | Ultrasonic characterization and multiscale analysis for the evaluation of dental implant stability: A sensitivity study | With the aim of surgical success, the evaluation of dental implant long-term stability is an important task for dentists. About that, the complexity of the newly formed bone and the complex boundary conditions at the bone-implant interface induce the main difficulties. In this context, for the quantitative evaluation o... | [
"Condensed Matter Physics",
"Materials Engineering",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
Q2045630 | ARREDO IN POROTEX | LA PROPOSTA PROGETTUALE MIRA A STUDIARE E SVILUPPARE UNA INNOVATIVA LINEA DI PRODOTTI DI ARREDO IN POROTEX (MOBILI PER LA CASA E PER L¿UFFICIO, DIVISORI E COMPLEMENTI DI ARREDO) CONFIGURABILI IN MODO DA ESSERE PERSONALIZZATI SECONDO LE SPECIFICHE ESIGENZE DEL CLIENTE, CHE POTRà ESSERE SIA IL CONSUMATORE FINALE, CHE A... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
219089 | The polya machinery: elucidating the molecular mechanisms of mrna polyadenylation, deadenylation and rna recognition | Gene expression is tightly regulated to allow rapid responses to cellular stimuli. In eukaryotes, the 3´ polyA tail of mRNAs plays key roles in post-transcriptional control. The Cleavage and Polyadenylation Factor (CPF), Ccr4–Not and Pan2–Pan3 multiprotein complexes add or remove polyA tails to regulate mRNA stability ... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Physiology in Health, Disease and Ageing"
] |
10.1051/0004-6361/201833576 | Planetary Tidal Interactions And The Rotational Evolution Of Low Mass Stars The Pleiades Anomaly | Context. The surface angular velocity evolution of low-mass stars is now globally understood and the main physical mechanisms involved in it are observationally quite constrained. However, while the general behaviour of these mechanisms is grasped, their theoretical description is still under ongoing work. This is the ... | [
"Universe Sciences"
] |
10.1016/j.fuel.2020.117186 | Nanoparticle modified polyacrylamide for enhanced oil recovery at harsh conditions | Silicon dioxide (SiO2) nanoparticles (NPs) have been recently proposed to increase the performance of polyacrylamide (PAM) for enhanced oil recovery (EOR) applications. However, SiO2/PAM nanocomposites tend to agglomerate or even desposit under harsh conditions such as high temperature-high salinity (HT-HS), which grea... | [
"Materials Engineering",
"Synthetic Chemistry and Materials",
"Physical and Analytical Chemical Sciences"
] |
W1983597949 | Scanning Structure–Activity Relationships with Structure–Activity Similarity and Related Maps: From <i>Consensus Activity Cliffs</i> to <i>Selectivity Switches</i> | Systematic description of structure-activity relationships (SARs) of data sets and structure-property relationships (SPRs) is of paramount importance in medicinal chemistry and other research fields. To this end, structure-activity similarity (SAS) maps are one of the first tools proposed to describe SARs using the con... | [
"Physical and Analytical Chemical Sciences",
"Computer Science and Informatics"
] |
218339 | High-Pressure hydrogen booster for distributed small-medium refuelling stations | The market of hydrogen refuelling stations is expected to thrive, with more than 400 stations by 2023 only in Germany. Hydrogen mobility is today the only reliable alternative to electric vehicles since it does not suffer the limits in autonomy and charging time affecting electric vehicles, opening promising perspectiv... | [
"Products and Processes Engineering",
"Materials Engineering",
"Systems and Communication Engineering"
] |
10.1126/science.aaw4295 | Protein crystallization promotes type 2 immunity and is reversible by antibody treatment | Although spontaneous protein crystallization is a rare event in vivo, Charcot-Leyden crystals (CLCs) consisting of galectin-10 (Gal10) protein are frequently observed in eosinophilic diseases, such as asthma. We found that CLCs derived from patients showed crystal packing and Gal10 structure identical to those of Gal10... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
617840 | Investigating the causes and consequences of replication stress in mammalian health | DNA damage (DD) is the cause of several diseases, including cancer, and it is also linked to the organ decline that arises in ageing. Yet, the contribution of different sources of DD to these processes is not understood. Sources of DD such as chromosome breaks, eroded telomeres or oxidative stress are been heavily inve... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Cell Biology, Development, Stem Cells and Regeneration",
"Physiology in Health, Disease and Ageing"
] |
311542 | Deciphering cytosolic antibacterial immunity: from triggering bacteriolysis to Aim2 inflammasome activation | Bacteria replicating within host cells either multiply in membrane-bound compartment or escape into the host cytosol. The host cytosol has long been considered as a safe haven for bacteria. However, the host cytosol is armed with an array of innate immune receptors detecting cytosolic invasion. Furthermore, the macroph... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
interreg_1851 | Miniaturization technology: synergies of research and innovation to enhance the economic development of the Adriatic | Public and Private entities in Adriatic and elsewhere have identified a challenge on finding a common language and field of interest between research & innovation and reaching a common understanding of the commercial imperatives in terms of economic and social development. IPATECH aims at developing a network for integ... | [
"Products and Processes Engineering",
"Individuals, Markets and Organisations",
"Institutions, Governance and Legal Systems"
] |
10.1038/s41598-018-36201-w | A critical review of anthropological studies on skeletons from European plague pits of different epochs | In historical times, plague epidemics intermittently ravaged Europe for more than 1,400 years, and still represent a threat in many countries all over the world. A debate is ongoing about the past plague, if it killed randomly in a population or discriminated among persons on the basis of their biological features. To ... | [
"The Study of the Human Past",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Environmental Biology, Ecology and Evolution"
] |
W1754464718 | Biological Responses of Agricultural Soils to Fly-Ash Amendment | The volume of solid waste produced in the world is increasing annually, and disposing of such wastes is a growing problem. Fly ash (FA) is a form of solid waste that is derived from the combustion of coal. Research has shown that fly ash may be disposed of by using it to amend agricultural soils. This review addresses ... | [
"Environmental Biology, Ecology and Evolution",
"Earth System Science"
] |
W1884262368 | PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes | Recently, it has been shown that an allele in the adiponutrin (PNPLA3) gene was strongly associated with increased liver fat content (LFC) and liver fibrosis independent of visceral adiposity and insulin resistance.In this study, we set out to determine whether the PNPLA3 rs738409 polymorphism was associated with liver... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physiology in Health, Disease and Ageing",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1002/ps.5677 | Target the core: durable plant resistance against filamentous plant pathogens through effector recognition | Plant pathogens colonize their host through the secretion of effector proteins that modulate plant metabolism and immune responses to their benefit. Plants evolve towards effector recognition, leading to host immunity. Typically, pathogen effectors are targets for recognition through plant receptors that are encoded by... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Environmental Biology, Ecology and Evolution"
] |
10.3389/fimmu.2017.00390 | Disarming cellular alarm systems-manipulation of stress-induced NKG2D ligands by human herpesviruses | The coevolution of viruses and their hosts led to the repeated emergence of cellular alert signals and viral strategies to counteract them. The herpesvirus family of viruses displays the most sophisticated repertoire of immune escape mechanisms enabling infected cells to evade immune recognition and thereby maintain in... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1007/JHEP03(2016)014 | Towards The Amplituhedron Volume | It has been recently conjectured that scattering amplitudes in planar N=4 super Yang-Mills are given by the volume of the (dual) amplituhedron. In this paper we show some interesting connections between the tree-level amplituhedron and a special class of differential equations. In particular we demonstrate how the ampl... | [
"Fundamental Constituents of Matter",
"Mathematics"
] |
W2340652522 | Mega-project meltdown: Post-politics, neoliberal urban regeneration and Valencia’s fiscal crisis | Drawing on the literature of post-politics and post-democracy, the literature of neoliberalism as mode of governance and the study of the city of Valencia’s long-standing emphasis on the development of prestige mega-projects of iconic architecture as a means to achieve economic regeneration and urban revitalisation, th... | [
"Institutions, Governance and Legal Systems",
"The Social World and Its Interactions",
"Human Mobility, Environment, and Space"
] |
10.1016/j.molcel.2012.05.048 | MCM8- and MCM9-Deficient Mice Reveal Gametogenesis Defects and Genome Instability Due to Impaired Homologous Recombination | We generated knockout mice for MCM8 and MCM9 and show that deficiency for these genes impairs homologous recombination (HR)-mediated DNA repair during gametogenesis and somatic cells cycles. MCM8-/- mice are sterile because spermatocytes are blocked in meiotic prophase I, and females have only arrested primary follicle... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Cell Biology, Development, Stem Cells and Regeneration",
"Integrative Biology: from Genes and Genomes to Systems"
] |
249397 | The eating body in Western practice and theory | Human bodies eat. But what does this entail? The proposed project will explore how the eating body is shaped in different Western practices. These will include nutritional research and health care clinics, sites that have a far-reaching impact on how we eat. Four related sub-projects will trace the most relevant contra... | [
"Studies of Cultures and Arts",
"Texts and Concepts",
"The Human Mind and Its Complexity"
] |
W973836814 | Air Pollution and Serum Glucose Levels | Recent studies demonstrated an adverse effect of chronic exposure to air pollution (AP) on metabolic syndrome and its components. In a population-based study, we investigated the association between exposure to ambient AP and serum glucose (SG), among subjects with normal glucose, impaired fasting glucose (IFG), and di... | [
"Earth System Science",
"Physiology in Health, Disease and Ageing"
] |
310890 | NLRs AS TRANSCRIPTIONAL REGULATORS | MHC molecules are central to our immune system and are therefore also involved in several pathologies. MHCII transcription is controlled by proximal promoter sequences, which are cooperatively bound by several factors forming the ‘MHC enhanceosome’. Upon recruitment to this complex, the NLR family member CIITA promotes... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
631104 | Catalytic reforming of glycerol to hydrogen and biopropane in hydrothermal media | The ultimate goal of this 15 months Fellowship, entitled “Catalytic Reforming of Glycerol to Hydrogen and Biopropane in Hydrothermal Media” (HYDROGAS) is to train a talented researcher through a research project focused on the development of novel process to make viable the use of the glycerol co-product derived during... | [
"Products and Processes Engineering",
"Physical and Analytical Chemical Sciences"
] |
221838 | A smart, energy autonomous, universal and cost-effective dynamic passenger information system | PIXEL is a Polish B2B SME, a pioneer and market leader in the development and delivery of passenger information system
in the Transport Sector. We operate in an industry that is expected to growth to $20.34 Billion by 2019 at a CAGR of 26.5%.
We develop all our innovative products with the belief and values of freedom ... | [
"Products and Processes Engineering",
"Systems and Communication Engineering",
"Computer Science and Informatics"
] |
320789 | A laser-cooled molecular fountain to measure the electron EDM | I propose to build an instrument that cools YbF molecules to microK temperature using laser light, and throws them up as a fountain in free fall. This will be used to detect CP-violating elementary particle interactions that caused our universe to evolve an excess of matter over antimatter These interactions cause th... | [
"Fundamental Constituents of Matter",
"Physical and Analytical Chemical Sciences"
] |
173887 | Deploying high capacity dense small cell heterogeneous networks | Broadband mobile networks are experiencing exponential traffic growth. It is predicted that this trend will continue in the next five to ten years with an estimated compound annual growth rate of 0.6 to 1.0. Hence the traffic (mostly data) carried by a mobile operator’s network in 2022 could be over 1000 times of that ... | [
"Systems and Communication Engineering",
"Computer Science and Informatics"
] |
984162 | Dna nanohydrogel loaded liposomal formulations for high loading efficiency of antimicrobial drugs against intracellular bacterial and topical biofilm infections | Dr. Sybil Obuobi was awarded her PhD in Pharmacy at the National University of Singapore (Singapore) in July 2018 and is very excited to pursue a postdoctoral fellowship at the University of Tromso The Arctic University of Norway (UiT, Norway) under the supervision of Prof. Natasa Skalko-Basnet, a renowned expert in ad... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases",
"Materials Engineering"
] |
W2220710686 | Should walking aids be used in the assessment of walking in persons with stroke? | Results: The results of the multiple regression analysis revealed that the number of single heel-raise repetitions and the passive range of motion for the ankle joint (dorsi-flexion with the knee flexed) were significantly correlated with the one-step value. Conclusion(s): Our data indicated that both an increased numb... | [
"Physiology in Health, Disease and Ageing",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1017/S0022377813000354 | Relativistic Collisionless Shocks Formation In Pair Plasmas | Collisionless shocks are ubiquitous in astrophysics and in the laboratory. Recent numerical simulations and experiments have shown how these can arise from the encounter of two collisionless plasma shells. When the shells interpenetrate, the overlapping region turns unstable, triggering the shock formation. As a first ... | [
"Fundamental Constituents of Matter",
"Universe Sciences"
] |
10.1002/cphc.201800935 | Microsecond Protein Dynamics from Combined Bloch-McConnell and Near-Rotary-Resonance R <inf>1p</inf> Relaxation-Dispersion MAS NMR | Studying protein dynamics on microsecond-to-millisecond (μs-ms) time scales can provide important insight into protein function. In magic-angle-spinning (MAS) NMR, μs dynamics can be visualized by R 1ρ rotating-frame relaxation dispersion experiments in different regimes of radio-frequency field strengths: at low RF fi... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
W2029605564 | Evaluation of Accuracy and Stability of the Classical SPH Method Under Uniaxial Compression | The accuracy and stability of the classical formulation of the smoothed particle hydrodynamics (SPH) method for modelling compression of elastic solids is studied to assess its suitability for predicting solid deformation. SPH has natural advantages for simulating problems involving compression of deformable solids ari... | [
"Condensed Matter Physics",
"Products and Processes Engineering"
] |
10.1016/j.ymeth.2018.03.014 | 3D structure determination of amyloid fibrils using solid-state NMR spectroscopy | The amyloid fold is structurally characterized by a typical cross-β architecture, which is under debate to represent an energy-favourable folding state that many globular or natively unfolded proteins can adopt. Being initially solely associated with amyloid fibrils observed in the propagation of several neurodegenerat... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
639070 | Accommodating New Interests at Sea: Legal Tools for Sustainable Ocean Governance | This research project will develop a theoretical framework and legal tools to aid scholars and stakeholders (law and policy-makers, private investors, environmental NGOs) in managing competing interests in the offshore economic sector. The offshore sector is expanding and activities at sea are increasing (e.g., deep se... | [
"Institutions, Governance and Legal Systems",
"Environmental Biology, Ecology and Evolution"
] |
W2969760028 | Flexible CO2 laser fiber: first look at the learning curve required in gynecological laparoscopy training | The advent of flexible CO2 laser fiber to gynecology arena might represent a turning point in the use of laser energy on a large-scale basis in gynecological surgery. However, there might be some concerns regarding the degree of surgical skills required to use the flexible system. The purpose of our study is to evaluat... | [
"Prevention, Diagnosis and Treatment of Human Diseases",
"Products and Processes Engineering"
] |
10.1086/685083 | Constancy In Functional Space Across A Species Richness Anomaly | The relationship between large-scale gradients in species richness and functional diversity provides important information regarding the mechanisms driving patterns of biodiversity. A classic hypothesis in ecology is that strong interspecific interactions should result in an increase in the functional volume of assembl... | [
"Environmental Biology, Ecology and Evolution"
] |
216089 | Communication systems for next-generation railways | MISTRAL will elaborate the Technical Specification of the future communication system for all railways in light of the migration from the current obsolete GSM-R.The new radio system will leverage the broadband capacity of IP-based wireless communication to enhance signaling but also to make possible innovative services... | [
"Systems and Communication Engineering",
"Products and Processes Engineering"
] |
10.1007/978-3-662-54365-8_7 | Removing Erasures With Explainable Hash Proof Systems | An important problem in secure multi-party computation is the design of protocols that can tolerate adversaries that are capable of corrupting parties dynamically and learning their internal states. In this paper, we make significant progress in this area in the context of password-authenticated key exchange (\(\textsf... | [
"Computer Science and Informatics"
] |
223143 | Influence-Based decision-making in uncertain environments | Decision-theoretic sequential decision making (SDM) is concerned with endowing an intelligent agent with the capability to choose actions that optimize task performance. SDM techniques have the potential to revolutionize many aspects of society and recent successes, e.g., agents that play Atari games and beat a world c... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
172011 | Product-Service symbiotic systems | Product-service solutions are not a novelty for manufacturing domain, in particular for Europe. Services are becoming more and more not just an optional adjunct to products, but they are integral part of manufacturing industries’ offer, able to differentiate the product value proposition, to take a significant part of ... | [
"Products and Processes Engineering",
"Computer Science and Informatics",
"Individuals, Markets and Organisations"
] |
10.1002/hbm.23586 | Comparing functional MRI protocols for small, iron-rich basal ganglia nuclei such as the subthalamic nucleus at 7 T and 3 T | The basal ganglia (BG) form a network of subcortical nuclei. Functional magnetic resonance imaging (fMRI) in the BG could provide insight in its functioning and the underlying mechanisms of Deep Brain Stimulation (DBS). However, fMRI of the BG with high specificity is challenging, because the nuclei are small and varia... | [
"Neuroscience and Disorders of the Nervous System",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
W1814326336 | Closing Schemas in Object-Relational Databases | Schema closure is a property that guarantees that no schema component has external references, that is, references to components that are not included in the schema. In the context of object-relational databases, schema closure implies that types, tables and views do not have references to components that are not inclu... | [
"Computer Science and Informatics"
] |
W2154533423 | No Counterpart of Visual Perceptual Echoes in the Auditory System | It has been previously demonstrated by our group that a visual stimulus made of dynamically changing luminance evokes an echo or reverberation at ~10 Hz, lasting up to a second. In this study we aimed to reveal whether similar echoes also exist in the auditory modality. A dynamically changing auditory stimulus equivale... | [
"Neuroscience and Disorders of the Nervous System"
] |
647963 | The Hatha Yoga Project: Mapping Indian and Transnational Traditions of Physical Yoga through Philology and Ethnography | Hatha was the name given in medieval India to a method of yoga in which physical practices predominate. Its origins are unclear, but some of its techniques can be traced to the first millennium BCE and it gradually became central to several Indian religious traditions, including, by the second half of the second millen... | [
"The Study of the Human Past",
"Texts and Concepts"
] |
10.1164/rccm.201203-0465PP | Malignant pleural effusion: Tumor-host interactions unleashed | Malignant pleural effusion (MPE) poses a significant clinical problem. Current nonetiologic management is suboptimal in terms of efficacy and safety. In light of recent research progress, we propose herein a new view of MPE development, which may rapidly translate into meaningful changes in therapeutics. In addition to... | [
"Immunity, Infection and Immunotherapy",
"Physiology in Health, Disease and Ageing",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
W4281788373 | Disentangling the Dynamics of VOCs and VOIs during the COVID-19 Pandemic in Peru using Bayesian Phylogenetics | Abstract At over 0.6% of the population, Peru has the highest SARS-CoV-2 mortality rate in the world. Much effort to sequence genomes was done in this country since mid-2020. However, an adequate analysis of the dynamics of the variants of concern and interest (VOCIs) is missing. We performed Bayesian phylodynamic anal... | [
"Integrative Biology: from Genes and Genomes to Systems",
"Mathematics",
"Environmental Biology, Ecology and Evolution"
] |
10.1007/978-3-642-38856-9_22 | Interpolation Based Verification Of Floating Point Programs With Abstract Cdcl | One approach for smt solvers to improve efficiency is to delegate reasoning to abstract domains. Solvers using abstract domains do not support interpolation and cannot be used for interpolation-based verification. We extend Abstract Conflict Driven Clause Learning (acdcl) solvers with proof generation and interpolation... | [
"Computer Science and Informatics"
] |
10.1016/j.plantsci.2018.05.001 | Thioredoxin-mediated redox signalling in plant immunity | Activation of plant immune responses is associated with rapid production of vast amounts of reactive oxygen and nitrogen species (ROS/RNS) that dramatically alter cellular redox homeostasis. Even though excessive ROS/RNS accumulation can cause widespread cellular damage and thus constitute a major risk, plant cells hav... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
CA 469505 A | AQUEOUS POLYURETHANE STOVING LACQUERS AND THE USE THEREOF FOR THE PRODUCTION OF LACQUER FILMS AND COATINGS | AQUEOUS POLYURETHANE STOVING LACQUERS AND THE USE THEREOF FOR THE PRODUCTION OF LACQUER FILMS AND COATINGS The present invention is directed to aqueous stoving lacquers containing pigments or fillers wherein the binders are based on combinations of (a) polyurethane prepolymers containing partly or completely neutralize... | [
"Synthetic Chemistry and Materials",
"Materials Engineering"
] |
10.1103/PhysRevB.98.195121 | Stability of the light-induced hidden charge density wave state within the phase diagram of 1 T-TaS2-xSex | The femtosecond transient optical spectroscopy is employed to study the relaxation dynamics of the equilibrium and hidden metastable charge-density-wave states in single crystals of 1T-TaS2-xSex as a function of the Se doping x. Similar to pristine 1T-TaS2, the transition to a hidden phase is observed at low temperatur... | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences"
] |
10.1111/rssb.12108 | The lasso for high dimensional regression with a possible change point | We consider a high dimensional regression model with a possible change point due to a covariate threshold and develop the lasso estimator of regression coefficients as well as the threshold parameter. Our lasso estimator not only selects covariates but also selects a model between linear and threshold regression models... | [
"Mathematics",
"Computer Science and Informatics"
] |
239781 | Legendrian contact homology and generating families | A contact structure on an odd dimensional manifold in a maximally non integrable hyperplane field. It is the odd dimensional counterpart of a symplectic structure. Contact and symplectic topology is a recent and very active area that studies intrinsic questions about existence, (non) uniqueness and rigidity of contact ... | [
"Mathematics"
] |
10.1007/s00209-014-1403-6 | On a conjecture of Gluck | Let (Formula presented. ) and (Formula presented. ) respectively denote the Fitting subgroup and the largest degree of an irreducible complex character of a finite group (Formula presented. ). A well-known conjecture of D. Gluck claims that if (Formula presented. ) is solvable then (Formula presented. ). We confirm th... | [
"Mathematics"
] |
222593 | Fast iot market take-up through the things networks | The Things Industries (TTI) is a Dutch SME that focuses on the rise of the Internet of Things (IoT). The company expects that, upon the further expansion of the digital economy, a number of societal developments will greatly affect our daily life. Leading in all these developments will be in the domain of the IoT, whic... | [
"Computer Science and Informatics",
"Systems and Communication Engineering",
"Individuals, Markets and Organisations"
] |
W2074307244 | Local government training in England and Wales, Denmark and Israel | This article highlights an interesting and often unduly neglected aspect of comparative public policy and administration: local government training. The argument advanced is that local government training based on the centrally focused model may tend to be: (i) skill-oriented and competence-framed; (ii) comprehensive; ... | [
"Institutions, Governance and Legal Systems",
"The Social World and Its Interactions"
] |
US 2013/0034331 W | HONEYCOMB PAPER | A consolidated fibrous mat comprises 20 to 50 weight percent of reinforcing fibers; and a continuous phase connecting the reinforcing fibers, comprising 50 to 70 weight percent of a polymer having a melt temperature at least 20°C lower than the reinforcing fibers, and 5 to 10 weight percent of a binder having a melt te... | [
"Materials Engineering",
"Synthetic Chemistry and Materials"
] |
10.1126/sciadv.aat7052 | Crystal structure of rhodopsin in complex with a mini-Gosheds light on the principles of G protein selectivity | Selective coupling of G protein (heterotrimeric guanine nucleotide–binding protein)–coupled receptors (GPCRs) to specific Gα-protein subtypes is critical to transform extracellular signals, carried by natural ligands and clinical drugs, into cellular responses. At the center of this transduction event lies the formatio... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physical and Analytical Chemical Sciences"
] |
10.1002/jimd.12061 | Ammonia and autophagy: An emerging relationship with implications for disorders with hyperammonemia | (Macro)autophagy/autophagy is a highly regulated lysosomal degradative process by which cells recycle their own nutrients, such as amino acids and other metabolites, to be reused in different biosynthetic pathways. Ammonia is a diffusible compound generated daily from catabolism of nitrogen-containing molecules and fro... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physiology in Health, Disease and Ageing",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
W2108375716 | Managing Transboundary Crises: Identifying the Building Blocks of an Effective Response System | In recent years, crises have become increasingly transboundary in nature. This exploratory paper investigates whether and how the transboundary dimensions of crises such as pandemics, cyber attacks and prolonged critical infrastructure failure accentuate the challenges that public and private authorities confront in th... | [
"Institutions, Governance and Legal Systems",
"The Social World and Its Interactions"
] |
10.1016/j.drudis.2014.06.024 | Factor XII: A drug target for safe interference with thrombosis and inflammation | Data from experimental animal models revealed an essential role for factor XII (FXII) in thrombotic occlusive diseases. In contrast to other blood coagulation factors, deficiency in the protease is not associated with abnormal bleeding from injury sites (hemostasis) in patients or in animals. Cumulatively, these findin... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
W2069103798 | Association between psychological distress and a sense of contribution to society in the workplace | Globally, mental health promotion related to psychological distress in the workplace has become a great concern, and a focus of much research attention. However, a sense of contribution to society and sense of bonding with the workplace have not been examined in relation to psychological distress. Thus, the purpose of ... | [
"The Human Mind and Its Complexity",
"The Social World and Its Interactions",
"Individuals, Markets and Organisations"
] |
215933 | Trusted online service for identity assurance | The objective of the overall innovation project is to commercialize a trusted online service for identity assurance (IDAaaS -
Identity Assurance as a Service). This service will be implemented according to European standards for electronic identity,
including eIDAS and STORK. The new service will be based on several ye... | [
"Computer Science and Informatics",
"Individuals, Markets and Organisations"
] |
W2009754871 | Timeliness of care and prognosis in patients with lung cancer | Timeliness of care is an important dimension of health care quality. The determining factors of less timely care and their influence on the survival of patients with lung cancer (LC) remain uncertain.To analyse the delays in the diagnosis and treatment of LC in our health area, the factors associated with the timelines... | [
"Prevention, Diagnosis and Treatment of Human Diseases",
"Physiology in Health, Disease and Ageing"
] |
10.1101/gad.2036411 | The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity | Heterochromatin integrity is crucial for genome stability and regulation of gene expression, but the factors involved in mammalian heterochromatin biology are only incompletely understood. Here we identify the oncoprotein DEK, an abundant nuclear protein with a previously enigmatic in vivo function, as a Suppressor of ... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems"
] |
W2056162906 | The Dry Valley Lakes, Antarctica: from sulfur stains on Earth to sulfur stains in the Jovian system | Most organisms dwell in what we consider to be normal environments, while others, which are called extremophiles,
may thrive in harsher conditions. These living organisms are mainly of unicellular (both prokaryotes and, to a lesser
extent, there are some eukaryotes) But the extremophiles also include multicellular or... | [
"Universe Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Earth System Science"
] |
10.1039/d0nr00868k | Size-dependent aggregation of hydrophobic nanoparticles in lipid membranes | Aggregation of hydrophobic spherical nanoparticles in lipid membranes depends on nanoparticle size. Nanoparticles of ∼3 nm sense and induce membrane curvature. | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences"
] |
259527 | ANALYTIC PROPERTIES OF INFINITE GROUPS:
limits, curvature, and randomness | The overall goal of this project is to develop new concepts and techniques in geometric and asymptotic group theory for a systematic study of the analytic properties of discrete groups. These are properties depending on the unitary representation theory of the group. The fundamental examples are amenability, discovere... | [
"Mathematics"
] |
GB 0105206 W | SUPPORTING BRACKET ASSEMBLY FOR A HORIZONTAL LIFELINE CABLE | A supporting bracket assembly for a horizontal lifeline cable (4) comprises a base plate (14), bracket means (24) and holding means (28) for the cable. The base plate (14) is provided for securing to a structure (6). The bracket means (24) is secured to the base plate and adapted for frictionally restrained pivotabilit... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
306484 | Implicit Programming | I propose implicit programming, a paradigm for developing reliable software using new programming language specification constructs and tools, supported through the new notion of software synthesis procedures. The paradigm will enable developers to use specifications as executable programming language constructs and wi... | [
"Computer Science and Informatics"
] |
10.1002/2014JB011850 | Experiments of dike-induced deformation: Insights on the long-term evolution of divergent plate boundaries | The shallow transport of magma occurs through dikes causing surface deformation. Our understanding of the effects of diking at the surface is limited, especially on the long term, for repeated intrusive episodes. We use analogue models to study the upper crustal deformation induced by dikes. We insert metal plates with... | [
"Earth System Science"
] |
W2591061288 | The Online Transportation Network in Indonesia: A Pendulum between the Sharing Economy and Ex Ante Regulation | The prominent role of innovation in the emerging digital market in Indonesia presents new challenges for current competition law and policy. Traditionally reliant on market definition for the analysis, the present competition law may not yet have sufficiently taken innovation into consideration. In the competition poli... | [
"Institutions, Governance and Legal Systems",
"Individuals, Markets and Organisations"
] |
10.1007/s10519-013-9628-4 | Three-and-a-half-factor model? the genetic and environmental structure of the CBCL/6-18 internalizing grouping | In the present article, multivariate genetic item analyses were employed to address questions regarding the ontology and the genetic and environmental etiology of the Anxious/Depressed, Withdrawn, and Somatic Complaints syndrome dimensions of the Internalizing grouping of the Child Behavior Checklist/6-18 (CBCL/6-18). ... | [
"Integrative Biology: from Genes and Genomes to Systems",
"The Human Mind and Its Complexity"
] |
10.1109/JESTPE.2017.2688454 | Linearized Modeling Methods Of Ac Dc Converters For An Accurate Frequency Response | Wideband harmonics and resonances are challenging the stability and power quality of emerging power-electronic-based power systems, and therefore, harmonic modeling and analysis of power converters are becoming even more important. However, the complex interactions on both ac and dc sides of a converter and the propaga... | [
"Systems and Communication Engineering",
"Products and Processes Engineering"
] |
W2043568647 | Spectroscopic and Computational Characterization of Substrate-Bound Mouse Cysteine Dioxygenase: Nature of the Ferrous and Ferric Cysteine Adducts and Mechanistic Implications | Cysteine dioxygenase (CDO) is a mononuclear non-heme Fe-dependent dioxygenase that catalyzes the initial step of oxidative cysteine catabolism. Its active site consists of an Fe(II) ion ligated by three histidine residues from the protein, an interesting variation on the more common 2-His-1-carboxylate motif found in m... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1074/jbc.R112.420752 | The mitochondrial calcium uniporter (MCU): Molecular identity and physiological roles | The direct measurement of mitochondrial [Ca2+] with highly specific probes demonstrated that major swings in organellar [Ca2+] parallel the changes occurring in the cytosol and regulate processes as diverse as aerobic metabolism and cell death by necrosis and apoptosis. Despite great biological relevance, insight was l... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physiology in Health, Disease and Ageing"
] |
10.1038/s41561-020-0623-0 | Coupled Southern Ocean cooling and Antarctic ice sheet expansion during the middle Miocene | The middle Miocene climate transition (~14 million years ago) was characterized by a dramatic increase in the volume of the Antarctic ice sheet. The driving mechanism of this transition remains under discussion, with hypotheses including circulation changes, declining carbon dioxide in the atmosphere and orbital forcin... | [
"Earth System Science"
] |
10.1186/s12968-015-0174-5 | 4D flow cardiovascular magnetic resonance consensus statement | Abstract Pulsatile blood flow through the cavities of the heart and great vessels is time-varying and multidirectional. Access to all regions, phases and directions of cardiovascular flows has formerly been limited. Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) has enabled more comprehensive access... | [
"Products and Processes Engineering",
"Prevention, Diagnosis and Treatment of Human Diseases",
"Systems and Communication Engineering",
"Physiology in Health, Disease and Ageing"
] |
W2025045283 | Assessing the Allocation of CDBG to Community Development Need | This article evaluates how well the current allocation formula for the Community Development Block Grant (CDBG) program allocates funds with respect to community development need. We assemble an index of community development need from a variety of demographic and economic indicators which capture the components of nee... | [
"Individuals, Markets and Organisations",
"Institutions, Governance and Legal Systems"
] |
W2025877554 | MEASUREMENT AND SIMULATION OF EQUATORIAL IONOSPHERIC PLASMA BUBBLES TO ASSESS THEIR IMPACT ON GNSS PERFORMANCE | Ionospheric anomaly is one of the major error sources which deteriorate the GNSS performance. In the equatorial region, effects of the ionospheric plasma bubbles are of great interest because they are pretty common phenomena, especially in the period of the high solar activity. In order to evaluate the GNSS performance... | [
"Systems and Communication Engineering",
"Earth System Science"
] |
10.1111/j.1365-2745.2012.02001.x | Strong persistent growth differences govern individual performance and population dynamics in a tropical forest understorey palm | Persistent variation in growth rate between individual plants can have strong effects on population dynamics as fast growers reach the reproductive size at an earlier age and thus potentially contribute more to population growth than slow growers. In tropical forests, such persistent growth differences have so far been... | [
"Environmental Biology, Ecology and Evolution"
] |
10.1261/rna.060442.116 | Understanding in-line probing experiments by modeling cleavage of nonreactive RNA nucleotides | Ribonucleic acid (RNA) is involved in many regulatory and catalytic processes in the cell. The function of any RNA molecule is intimately related with its structure. In-line probing experiments provide valuable structural data sets for a variety of RNAs and are used to characterize conformational changes in riboswitche... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1016/j.neuron.2016.02.033 | Membrane Lipids in Presynaptic Function and Disease | Lipids are the most abundant organic compounds in the brain. The brain has a unique lipidome, and changes in lipid concentration, organization, and metabolism are associated with many neuronal diseases. Here, we discuss recent advances in understanding presynaptic membrane lipid organization, centered on illustrative e... | [
"Neuroscience and Disorders of the Nervous System",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
EP 81107405 A | Spreader vehicle for solid and liquid thawing materials. | Streufahrzeug (1) mit Streuvorrichtungen und je einem Behälter (2, 3) für granulierte und flüssige Taustoffe, mit der die granulierten und die flüssigen Taustoffe wahlweise jeweils separat oder gemischt über eine maximale Streubreite von ca. 25 m als auch in beliebig schmaleren Streubreiten mit gleicher oder unterschie... | [
"Products and Processes Engineering",
"Systems and Communication Engineering"
] |
615709 | Understanding evolutionary rates on the Tree of Life in time and space | According to models of adaptive radiation and sexual selection trait divergence is a key step in the speciation process. At a macroevolutionary scale this leads to the prediction that speciation is driven by the rate of trait evolution rather than the state of the trait. Despite the established theoretical links betwee... | [
"Environmental Biology, Ecology and Evolution",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1038/s41380-018-0321-0 | Big data approaches to decomposing heterogeneity across the autism spectrum | Autism is a diagnostic label based on behavior. While the diagnostic criteria attempt to maximize clinical consensus, it also masks a wide degree of heterogeneity between and within individuals at multiple levels of analysis. Understanding this multi-level heterogeneity is of high clinical and translational importance.... | [
"Neuroscience and Disorders of the Nervous System",
"Integrative Biology: from Genes and Genomes to Systems",
"Computer Science and Informatics"
] |
10.1063/1.4737646 | Light Sailboats Laser Driven Autonomous Microrobots | We introduce a system of light driven microscopic autonomous moving particles that move on a flat surface. The design is simple, yet effective: Micrometer sized objects with wedge shape are produced by photopolymerization, and they are covered with a reflective surface. When the area of motion is illuminated perpendicu... | [
"Synthetic Chemistry and Materials",
"Materials Engineering",
"Condensed Matter Physics"
] |
10.1088/1475-7516/2019/11/017 | Reconstructing The Spectral Shape Of A Stochastic Gravitational Wave Background With Lisa | We present a set of tools to assess the capabilities of LISA to detect and reconstruct the spectral shape and amplitude of a stochastic gravitational wave background (SGWB) . We first provide the LISA power-law sensitivity curve and binned power-law sensitivity curves, based on the latest updates on the LISA design. Th... | [
"Universe Sciences",
"Fundamental Constituents of Matter",
"Computer Science and Informatics"
] |
10.1038/ncomms15736 | Water pumping in mantle shear zones | Water plays an important role in geological processes. Providing constraints on what may influence the distribution of aqueous fluids is thus crucial to understanding how water impacts Earth's geodynamics. Here we demonstrate that ductile flow exerts a dynamic control on water-rich fluid circulation in mantle shear zon... | [
"Earth System Science",
"Condensed Matter Physics"
] |
10.1021/jacs.8b11752 | Base-Promoted, Remote C-H Activation at a Cationic (n <sup>5</sup> -C <inf>5</inf> Me <inf>5</inf> )Ir(III) Center Involving Reversible C-C Bond Formation of Bound C <inf>5</inf> Me <inf>5</inf> | C-H bond activation at cationic [(n 5 -C 5 Me 5 )Ir(PMe 2 Ar′)] centers is described, where PMe 2 Ar′ are the terphenyl phosphine ligands PMe 2 Ar Xyl2 and PMe 2 Ar Dipp2 . Different pathways are defined for the conversion of the five-coordinate complexes [(n 5 -C 5 Me 5 )IrCl(PMe 2 Ar′)] + , 2(Xyl) + and 2(Dipp) + , i... | [
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
758427 | Novel Blueprints for the Visible-Light-Mediated Assembly of C–N Bonds via Nitrogen Radicals | Nitrogen-containing compounds underpin every aspect of our daily life as they form the structural basis of almost all pharmaceuticals, agrochemicals, food additives and materials. The invention of methods for the formation of bonds between C and N atoms is of strategic importance for the discovery and evolution of mole... | [
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
10.1126/science.aar8048 | Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation | The onset of inflammation is associated with reactive oxygen species and oxidative damage to macromolecules like 7,8-dihydro-8-oxoguanine (8-oxoG) in DNA. Because 8-oxoguanine DNA glycosylase 1 (OGG1) binds 8-oxoG and because Ogg1-deficient mice are resistant to acute and systemic inflammation, we hypothesized that OGG... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1371/journal.pcbi.1003736 | Structure-Function Discrepancy: Inhomogeneity and Delays in Synchronized Neural Networks | The discrepancy between structural and functional connectivity in neural systems forms the challenge in understanding general brain functioning. To pinpoint a mapping between structure and function, we investigated the effects of (in)homogeneity in coupling structure and delays on synchronization behavior in networks o... | [
"Neuroscience and Disorders of the Nervous System",
"Mathematics"
] |
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