id
stringlengths
6
42
title
stringlengths
3
499
abstract
stringlengths
0
6.24k
label
listlengths
0
6
10.1126/scitranslmed.aac5380
DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates
DEL-1 (developmental endothelial locus-1) is an endothelial cell-secreted protein that regulates LFA-1 (lymphocyte function-associated antigen-1) integrin-dependent leukocyte recruitment and inflammation in various tissues. We identified a novel regulatory mechanism of DEL-1 in osteoclast biology. Specifically, we show...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
2728695
Early detection and progress monitoring and prediction of corrosion in aeronautic al alloys through calibrated ultrasonic corrosion sensors application
Corrosion is a dynamic process in which propagation rate remains difficult to predict and varies depending on the type of corrosion occurring (pitting, intergranular, exfoliation,filiform, corrosion-fatigue and SCC). Currently, the presence of corrosion damages may be detected by means of NDT. However, corrosion initia...
[ "Products and Processes Engineering", "Materials Engineering", "Systems and Communication Engineering" ]
10.1093/nar/gkw385
Peptiderive server: derive peptide inhibitors from protein-protein interactions
The Rosetta Peptiderive protocol identifies, in a given structure of a protein-protein interaction, the linear polypeptide segment suggested to contribute most to binding energy. Interactions that feature a 'hot segment', a linear peptide with significant binding energy compared to that of the complex, may be amenable ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Computer Science and Informatics" ]
W2028961894
Racial and Socioeconomic Status Differences in Depressive Symptoms Among Black and White Youth: An Examination of the Mediating Effects of Family Structure, Stress and Support
Stress research shows that race, socioeconomic status (SES), and family context significantly impact an adolescent's psychological well-being, yet little is known about the mediating effects of family context on racial and SES differences in depressive symptoms among Black and White youth. We investigate these associat...
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity" ]
W4211263703
Abric de la Ratlla del Bubo (Crevillent, Alicante). Resultados de las campañas de 1986-1991. Nuevos datos sobre su secuencia paleolítica
El Abric de la Ratlla del Bubo (Crevillent, Alicante) es uno de los yacimientos clave para el conocimiento del Paleolítico superior en el área central del Mediterráneo ibérico, especialmente en lo que a sus fases iniciales se refiere. El yacimiento ha sido objeto de varias intervenciones arqueológicas, tanto clandestin...
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]
W2901801939
Vegetation Optical Depth and Soil Moisture Retrieval Using L-Band Radiometry Over the Entire Growing Season of a Winter Wheat Stand
This paper describes the first results of a field experiment conducted at the Selhausen remote sensing field laboratory (Germany) over the entire growing season of a winter wheat. Brightness temperature measurements were performed with the passive microwave L-band radiometer ELBARA-II. The data were collected above two...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
W2260312074
Experimental Evaluation of Shear Strength of an Innovative Splice for Prestressed Precast Concrete Girders
AbstractThis paper describes shear laboratory testing of a joint design for spliced, prestressed precast I-girders. Although the connection is not intended to be placed at locations of high shear, the potential for shear-type failures was investigated. Shear testing of the spliced beam specimens is described and behavi...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1063/1.4973520
Dual Phase Grating Interferometer For Tunable Dark Field Sensitivity
Hard X-ray dark-field and phase contrast imaging using grating interferometry have shown great potential for medical and industrial applications. However, the wide spread applicability of the method is challenged by a number of technical related issues such as relatively low dose and flux efficiency due to the absorpti...
[ "Condensed Matter Physics", "Systems and Communication Engineering", "Prevention, Diagnosis and Treatment of Human Diseases" ]
281422
Toward Eco-Evolutionary Models for BIODiversity Scenarios
Given the contemporary biodiversity crisis, effective conservation strategies that offset the threats to ecosystem integrity are crucial for maintaining biodiversity. The development of sound biodiversity scenarios is thus a major challenge for the scientific community. However, current biodiversity models rarely incor...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
10.1051/0004-6361/202037690
Synthetic Observations Of Spiral Arm Tracers Of A Simulated Milky Way Analog
Context: The Faraday rotation measure (RM) is often used to study the magnetic field strength and orientation within the ionized medium of the Milky Way. Observations indicate a RM in the spiral arms that exceeds the commonly assumed range. This raises the question of under what conditions spiral arms create such stron...
[ "Universe Sciences" ]
10.1038/ncb2999
Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein
Growing microtubule end regions recruit a variety of proteins collectively termed +TIPs, which confer local functions to the microtubule cytoskeleton. +TIPs form dynamic interaction networks whose behaviour depends on a number of potentially competitive and hierarchical interaction modes. The rules that determine which...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2095067953
Managing Information for a Risk Based Approach to Stakeholder Management
This paper proposes a risk based approach in order to obtain a quantitative estimate of the salience of the stakeholders involved in a project. The integration between stakeholders and risk management processes in the Project Management System allows us to realize a twofold objective: a quantitative estimate of the sal...
[ "Individuals, Markets and Organisations", "Computer Science and Informatics" ]
10.1016/j.orgel.2019.03.014
Enhanced exciton harvesting in a planar heterojunction organic photovoltaic device by solvent vapor annealing
The singlet exciton diffusion length was measured in a small molecule electron donor material DR3TBDTT using fluorescence quenching at a planar interface with a cross-linked fullerene derivative. The one-dimensional exciton diffusion length was increased from ~16 to ~24 nm by annealing the film in carbon disulfide solv...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
W2903654494
The Influence of Dust and Black Carbon on Clouds, in Africa
The aerosol can change the clouds properties; the clouds, however, affect the normal behavior of aerosol optical depth. Considerable effects arise while the interaction of aerosol and clouds unavoidably encounters the presence of greenhouse gases (GHGs) in atmosphere. This research discusses the influence of two select...
[ "Earth System Science", "Physical and Analytical Chemical Sciences" ]
10.1038/nrclinonc.2016.195
RECIST-learning from the past to build the future
Response Evaluation Criteria In Solid Tumours (RECIST) remain an integral part of the assessment of tumour burden in many clinical trials in oncology; these criteria are used to evaluate the activity and efficacy of new cancer therapeutics in solid tumours. We aim to define the purpose of RECIST, and reflect on the lev...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
10.1016/j.jas.2013.01.025
Ochre resources from the Middle Stone Age sequence of Diepkloof Rock Shelter, Western Cape, South Africa
Although no paintings are associated with archaeological contexts before the end of the Middle Stone Age, hundreds of ochre pieces were discovered on numerous southern African sites suggesting a lasting tradition of ochre use. The variability and the significance of ochre exploitation remain however poorly documented. ...
[ "The Study of the Human Past", "Physical and Analytical Chemical Sciences", "Earth System Science" ]
W1970087463
A Critical Revision of the Nano-Morphology of Proton Conducting Ionomers and Polyelectrolytes for Fuel Cell Applications
A few aspects of the nano-morphology of hydrated Nafion and other ionomers and polyelectrolytes in their acid form are revisited by examining the evolution of small angle X-ray scattering (SAXS) data which are recorded for a wide range of water volume fractions (Φwater ≈ 7–56 vol%). A consistency check with the recent ...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
US 18527208 A
Exposure apparatus and method of manufacturing device
This invention provides a positioning apparatus which can safely stop a movable body irrespective of its driving status. This invention relates to a positioning apparatus which positions a movable body (4) of an exposure apparatus and includes a driver (2) which drives the movable body (4), a power source (3) which sup...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1016/j.neuron.2014.12.006
Vesicular Release Statistics and Unitary Postsynaptic Current at Single GABAergic Synapses
The existence of vesicular docking sites in central synapses is supported by morphological and biochemical evidence, but their functional role remains elusive. To investigate this role we have studied single depressing GABAergic synapses where multivesicular release and postsynaptic receptor saturation have been docume...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1093/eurheartj/ehy249
CRISPR/Cas9 editing in human pluripotent stemcell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy
Aims Sarcomeric gene mutations frequently underlie hypertrophic cardiomyopathy (HCM), a prevalent and complex condition leading to left ventricle thickening and heart dysfunction. We evaluated isogenic genome-edited human pluripotent stem cell-cardiomyocytes (hPSC-CM) for their validity to model, and add clarity to, HC...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
294519
Practical statistical approaches for addressing replicability problems in life sciences
Lack of replicability of scientific discoveries has surfaced too often in recent years, and even reached the attention of the general public. An ignored cause is the inappropriate statistical treatment of two statistical problems: (1) selective inference, manifested in selecting few promising leads following the statis...
[ "Neuroscience and Disorders of the Nervous System", "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1088/1468-6996/16/4/043501
A Meta Analysis Of The Mechanical Properties Of Ice Templated Ceramics And Metals
Ice templating, also known as freeze casting, is a popular shaping route for macroporous materials. Over the past 15 years, it has been widely applied to various classes of materials, and in particular ceramics. Many formulation and process parameters, often interdependent, affect the outcome. It is thus difficult to u...
[ "Materials Engineering", "Synthetic Chemistry and Materials" ]
758604
Enhancing brain function and cognition via artificial entrainment of neural oscillations
Neural oscillations are ubiquitous in the human brain and have been implicated in diverse cognitive functions to support both neural communication and plasticity. Their functional relevance is further supported by a large number of studies linking various cognitive deficits (e.g., attention deficit hyperactivity disord...
[ "Neuroscience and Disorders of the Nervous System", "Computer Science and Informatics", "The Human Mind and Its Complexity" ]
10.1109/PTC.2015.7232799
Coordinated Frequency And Voltage Overload Control Of Smart Transformers
A Smart Transformer (ST) is a power electronics-based transformer that aims not only to substitute the traditional transformer but to upgrade also the LV and MV grid. In order to limit the costs, the ST must be carefully designed, constraining the current carried by the ST. In this paper a Combined Frequency and Voltag...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
222761
Swine diseases field diagnostics toolbox
The increased population density in modern animal production systems has made them vulnerable to various transboundary infectious agents & diseases. During the last decades in the developed world, a reduction in the direct burden of livestock diseases has been observed, because of more effective drugs & vaccines. Howev...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases", "Systems and Communication Engineering", "Biotechnology and Biosystems Engineering" ]
W4313257699
Metropolitan Research: Methodes and Approaches. Bielefeld: transcript Verlag,
quel impact sur la transformation et la valorisation territoriales?
[ "Human Mobility, Environment, and Space" ]
175043
Interethnic relationships in contemporary communities: how does ethnoracial diversity affect in- and out-group trust, solidarity, and cooperation
The increasingly multiethnic nature of modern societies has spurred academic interest in the consequences of diversity. Recent scholarship has linked ethnoracial diversity to undesirable collective outcomes, e.g., low levels of trust, civic engagement, and social capital. These findings have important policy implicatio...
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity" ]
10.1016/j.pharmthera.2019.01.002
Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity
Individuals differ substantially in their response to pharmacological treatment. Personalized medicine aspires to embrace these inter-individual differences and customize therapy by taking a wealth of patient-specific data into account. Pharmacogenomic constitutes a cornerstone of personalized medicine that provides th...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2791062283
Origin of enhanced catalytic activity of oxygen reduction reaction on zirconium oxynitrides: A first-principle study
Abstract To clarify the origin of the enhanced catalytic activity of zirconium oxynitrides, the first-principle calculation method is carried out to study the oxygen reduction reaction (ORR) on monoclinic ZrO 2 and cubic Zr 2 ON 2 (011) surfaces. The relation of the d -orbital occupation of nonequivalence Zr atoms and ...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
1262292
Ice core dating tools revisited to infer the dynamic of glacial – interglacial transitions over the last 1.5 million years
The Quaternary period (last 2600 thousands of years, hereafter ka) is the ideal period to evaluate our understanding of climate processes with general circulation models (GCM) used for prediction of future climate. During this period, the largest climate changes are glacial – interglacial transitions, hereafter termina...
[ "Earth System Science", "Physical and Analytical Chemical Sciences" ]
W2225313598
Single-port sleeve gastrectomy, a valuable procedure in the treatment of morbidly obese patients
Background Laparoscopic sleeve gastrectomy has recently been proposed as a sole bariatric procedure because of the considerable weight loss that is achieved in morbidly obese patients. Single-incision laparoscopic sleeve gastrectomy has recently gained acceptance in bariatric surgery as the procedure has possible benef...
[ "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases" ]
US 2013/0050939 W
ADAPTIVE ACCESS POINT DATABASE MANAGEMENT
Method and system for providing information of an access point database are disclosed. In one embodiment, a method of providing information of an access point database comprises receiving a request to access an access point database from a mobile client, generating a segment of the access point database in accordance w...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1103/PhysRevD.89.045009
Embedding tensor of Scherk-Schwarz flux compactifications from eleven dimensions
We study the Scherk-Schwarz reduction of D=11 supergravity with background fluxes in the context of a recently developed framework pertaining to D=11 supergravity. We derive the embedding tensor of the associated four-dimensional maximal gauged theories directly from eleven dimensions by exploiting the generalized viel...
[ "Fundamental Constituents of Matter", "Mathematics" ]
890810
Aicraft design and noise rating for regional aicraft
Aicraft Design and nOise RatiNg for regiOnal aicraft. The activities related to the ADORNO project are focused on the development of aircraft models for a regional aircraft engine platform. The main objective is to provide aircraft requirements (e.g. thrusts, offtakes, etc.) as well as trade factors for specific fu...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
CA 2020050405 W
METHOD AND APPARATUS FOR MEASURING AIRWAY RESISTANCE
A device for measuring lung function parameters using quiet exhalation has a flow tube with a mouthpiece end and an outlet, a shutter covering the outlet of the flow tube, a controllable latch closing and releasing the shutter, a flow sensor for measuring flow in the flow tube following release of the shutter, a pressu...
[ "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1038/s41591-018-0165-9
Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo
Mutations of the mitochondrial genome (mtDNA) underlie a substantial portion of mitochondrial disease burden. These disorders are currently incurable and effectively untreatable, with heterogeneous penetrance, presentation and prognosis. To address the lack of effective treatment for these disorders, we exploited a rec...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2905624393
Determinación del tiempo improductivo “Making do” y su relación con la pérdida económica en obras de Ingeniería Civil
There are different situations that generate unproductive times in Civil Engineering works, the purpose of this research is to publish about a new type of loss by flows, called Making do or “hacer por hacer”, this type of waste appears when an activity is carried out without considering all the resources that intercede...
[ "Products and Processes Engineering" ]
756365
Phononic Circuits: manipulation and coherent control of phonons
In the last decades, the power to control photons and electrons paved the way for extraordinary technological developments in electronic and optoelectronic applications. The same degree of control is still lacking with quantized lattice vibrations, i.e. phonons. Phonons are the carriers of heat and sound. The understan...
[ "Condensed Matter Physics", "Systems and Communication Engineering", "Materials Engineering" ]
682588
Foundations of Factorized Data Management Systems
The objective of this project is to investigate scalability questions arising with a new wave of smart relational data management systems that integrate analytics and query processing. These questions will be addressed by a fundamental shift from centralized processing on tabular data representation, as supported by tr...
[ "Computer Science and Informatics" ]
10.1371/journal.pone.0180516
Bayesian spatio-temporal modeling of mortality in relation to malaria incidence in Western Kenya
Introduction: The effect of malaria exposure on mortality using health facility incidence data as a measure of transmission has not been well investigated. Health and demographic surveillance systems (HDSS) routinely capture data on mortality, interventions and other household related indicators, offering a unique plat...
[ "Earth System Science", "Prevention, Diagnosis and Treatment of Human Diseases", "Mathematics" ]
10.3389/fimmu.2018.00804
Flexible signaling of Myeloid C-type lectin receptors in immunity and inflammation
Myeloid C-type lectin receptors (CLRs) are important sensors of self and non-self that work in concert with other pattern recognition receptors (PRRs). CLRs have been previously classified based on their signaling motifs as activating or inhibitory receptors. However, specific features of the ligand binding process may...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1364/OE.25.029874
Comparison Of Nematic Liquid Crystal And Dmd Based Spatial Light Modulation In Complex Photonics
Digital micro-mirror devices (DMDs) have recently emerged as practical spatial light modulators (SLMs) for applications in photonics, primarily due to their modulation rates, which exceed by several orders of magnitude those of the already well-established nematic liquid crystal (LC)-based SLMs. This, however, comes at...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1126/science.1226719
A quantum delayed-choice experiment
Quantum systems exhibit particle- or wavelike behavior depending on the experimental apparatus they are confronted by. This wave-particle duality is at the heart of quantum mechanics. Its paradoxical nature is best captured in the delayed-choice thought experiment, in which a photon is forced to choose a behavior befor...
[ "Fundamental Constituents of Matter" ]
10.1257/jel.51.1.5
Structural Models of Nonequilibrium Strategic Thinking: Theory, Evidence, and Applications
Most applications of game theory assume equilibrium, justified by presuming either that learning will have converged to one, or that equilibrium approximates people's strategic thinking even when a learning justification is implausible. Yet several recent experimental and empirical studies suggest that people's initial...
[ "Individuals, Markets and Organisations", "The Human Mind and Its Complexity" ]
W1823377470
Lipid and protein stability of partially defatted walnut flour (Juglans regia L.) during storage
Summary Partially defatted walnut flour (WF) was stored (25 °C, 800 Lux) for an 8-month period and evaluated monthly in some protein properties and oil oxidative parameters. Transparent plastic-laminated (WFPL) and plastic-laminated, aluminium-coated (WFAC) packages were used. During the first 3 months, samples were...
[ "Products and Processes Engineering", "Materials Engineering", "Physical and Analytical Chemical Sciences" ]
10.1016/j.prostaglandins.2017.06.003
The novel lipid mediator PD1<inf>n-3 DPA</inf>: An overview of the structural elucidation, synthesis, biosynthesis and bioactions
Resolvins, protectins and maresins are individual families of specialized pro-resolving mediators biosynthesized from the dietary n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid. These enzymatically oxygenated polyunsaturated lipid mediators were first elucidated during the resolution pha...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1101/gad.241661.114
Evolutionally dynamic L1 regulation in embryonic stem cells
Mobile elements are important evolutionary forces that challenge genomic integrity. Long interspersed element-1 (L1, also known as LINE-1) is the only autonomous transposon still active in the human genome. It displays an unusual pattern of evolution, with, at any given time, a single active L1 lineage amplifying to th...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
W2239119861
A study on enhanced recovery after abdominal surgery
Background Enhanced recovery after surgery or fast-track surgery is a set of protocols aimed to reduce the physiological burden of surgery, thus improving outcomes. Fast-track surgery aims to use evidence-based practice to reduce complications, improve postoperative quality of life, and decrease hospital length of stay...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
10.5194/bg-13-1387-2016
Modeling spatiotemporal dynamics of global wetlands: comprehensive evaluation of a new sub-grid TOPMODEL parameterization and uncertainties
. Simulations of the spatiotemporal dynamics of wetlands are key to understanding the role of wetland biogeochemistry under past and future climate. Hydrologic inundation models, such as the TOPography-based hydrological model (TOPMODEL), are based on a fundamental parameter known as the compound topographic index (CTI...
[ "Earth System Science", "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1016/j.semradonc.2013.05.008
Optimization of Tumor Radiotherapy With Modulators of Cell Metabolism: Toward Clinical Applications
Most solid tumors are characterized by unstable perfusion patterns, creating regions of hypoxia that are detrimental to radiotherapy treatment response. Because postsurgical radiotherapy, alone or in combination with other interventions, is a first-line treatment for many malignancies, strategies aimed at homogeneously...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
221914
Commentary manuscripts in the history and transmission of the greek new testament
Manuscripts which contain commentary alongside the biblical text are some of the most significant and complicated witnesses to the Greek New Testament. First compiled around the fifth century, the commentaries consist of chains of extracts from earlier writers (catenae). These manuscripts became the main way in which u...
[ "The Study of the Human Past", "Texts and Concepts" ]
771237
Deformation Mechanisms are the Key to Understanding and Tayloring Tribological Behaviour
Tribology, the science of interacting surfaces in relative motion, is crucial for many aspects of modern life. Friction and wear decisively impact the lifetime and durability of many products-from nanoelectromechanical systems to gears and engines. In the USA alone, an estimated 1E18 joules of energy could be saved eac...
[ "Materials Engineering", "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Computer Science and Informatics" ]
10.1016/j.jad.2011.08.006
The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder
Background: It has recently been hypothesized that bipolar disorders are associated with accelerated aging. Telomere dysfunction, a biomarker of aging, is determined by the load of short telomeres, rather than by the mean telomere length. To our knowledge, the load of short telomeres has not been reported in any psychi...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
W2366955217
Safety evaluation of high-piled wharf based on fuzzy analytic hierarchy process
Many factors affect the safety of high-piled wharf.The traditional safety assessment method for the high-piled wharf mainly relies on the test results of the qualitative analysis,and seldom on the accurate quantitative evaluation.In order to analyze the safety conditions of high-piled wharf accurately,this paper carrie...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1016/j.febslet.2009.10.071
Coordination of gene expression with growth rate: A feedback or a feed-forward strategy?
In the budding yeast, a large fraction of genes is coordinately regulated with growth rate. We argue that this correlation does not reflect a direct feedback from growth rate to gene expression. Rather, what appears to be a response to growth rate is dominated by environmental sensing. External parameters, such as nutr...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
W3188613116
Crecimiento económico y flujos de efectivo en las empresas del sector servicios de Cundinamarca
Through this thesis research, which aims to measure the existing relational effect between economic growth and cash flows of the service sector in the department of Cundinamarca it is exposed. And from there propose a model that allows the prediction of future cash flows by reference to economic growth. For this work f...
[ "Individuals, Markets and Organisations" ]
W4214929569
Intravenous iron treatment-induced hypophosphatemia
Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the management of patients with diffuse large B-cell lymphoma (DLBCL) who are refractory or relapse after immunochemotherapy. This strategy consists in genetically modifying the patient's own T lymphocytes to favor the recognition of selected tumor ant...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1109/TPAMI.2016.2567384
Learning To Generate Chairs Tables And Cars With Convolutional Networks
We train generative ‘up-convolutional’ neural networks which are able to generate images of objects given object style, viewpoint, and color. We train the networks on rendered 3D models of chairs, tables, and cars. Our experiments show that the networks do not merely learn all images by heart, but rather find a meaning...
[ "Computer Science and Informatics" ]
W2004530964
Noradrenaline-induced spontaneous inhibitory postsynaptic currents in mouse basolateral nucleus of amygdala pyramidal neurons: Comparison with dopamine-induced currents
The basolateral nucleus of the amygdala (BLA) receives both noradrenergic and dopaminergic projections. These projections are thought to be important for modulation of amygdala neural circuits. In BLA pyramidal neurons, noradrenaline (NA) is known to facilitate gamma-aminobutyric acid (GABA)ergic spontaneous inhibitory...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
interreg_1379
Fostering tourism innovation system in Adriatic-Ionian Region
Project FOST INNO aims to contribute to the long term growth of tourism in the Adriatic Ionian region through innovations capacity building. Common challenges of the programme area as; prolonging tourism season, improving quality in tourism and fostering better tourism employment conditions, are going to be tackled in ...
[ "Human Mobility, Environment, and Space", "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems" ]
10.1038/s41467-019-10662-7
Intracavity optical trapping of microscopic particles in a ring-cavity fiber laser
Standard optical tweezers rely on optical forces arising when a focused laser beam interacts with a microscopic particle: scattering forces, pushing the particle along the beam direction, and gradient forces, attracting it towards the high-intensity focal spot. Importantly, the incoming laser beam is not affected by th...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1038/s41598-019-56267-4
Methanogenic Archaea Can Produce Methane in Deliquescence-Driven Mars Analog Environments
The current understanding of the Martian surface indicates that briny environments at the near-surface are temporarily possible, e. g. in the case of the presumably deliquescence-driven Recurring Slope Lineae (RSL). However, whether such dynamic environments are habitable for terrestrial organisms remains poorly under...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Earth System Science" ]
W2963385418
Temporal correlation detection using computational phase-change memory
For decades, conventional computers based on the von Neumann architecture have performed computation by repeatedly transferring data between their processing and their memory units, which are physically separated. As computation becomes increasingly data-centric and as the scalability limits in terms of performance and...
[ "Computer Science and Informatics", "Condensed Matter Physics", "Materials Engineering" ]
10.1063/1.4991731
Pressure In An Exactly Solvable Model Of Active Fluid
We consider the pressure in the steady-state regime of three stochastic models characterized by self-propulsion and persistent motion and widely employed to describe the behavior of active particles, namely, the Active Brownian particle (ABP) model, the Gaussian colored noise (GCN) model, and the unified colored noise ...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
W1601674774
Capture and Analysis of Newly Synthesized RNA A Novel Enabling Technology to Study High Resolution Gene Expression
RP-70 Newly transcribed RNA contains valuable information of the transcriptome. Development of enabling technologies using affinity nucleosides will help accelerate research that depends on high resolution gene expression. We describe an enabling tool based on click chemistry, which begins with metabolic incorporati...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Physical and Analytical Chemical Sciences" ]
10.1016/j.jorganchem.2017.02.045
Synthesis, structures and photoluminescence properties of silver complexes of cyclic (alkyl)(amino)carbenes
Silver complexes of cyclic (alkyl)(amino)carbenes (CAACs), (RL)nAgX (n = 1, X = Cl, Br, I; n = 2, X = OTf; R = Me2, Et2, or adamantyl) are accessible in high yields by reacting free carbenes with silver salts. The smaller carbene ligand Me2L leads to the formation of a mixture of neutral (Me2L)AgCl and cationic [(Me2L)...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1177/2053168017707151
Willing to share? Tax compliance and gender in Europe and America
Studies examining the effects of gender on honesty, deceptive behavior, pro-sociality, and risk aversion, often find significant differences between men and women. The present study contributes to the debate by exploiting one of the largest tax compliance experiments to date in a highly controlled environment conducted...
[ "The Social World and Its Interactions", "Individuals, Markets and Organisations" ]
10.1007/s10654-019-00502-9
The early growth genetics (Egg) and early genetics and lifecourse epidemiology (eagle) consortia: Design, results and future prospects
The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and d...
[ "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases", "Environmental Biology, Ecology and Evolution" ]
10.1145/3290605.3300638
Magnetips Combining Fingertip Tracking And Haptic Feedback For Around Device Interaction
Around-device interaction methods expand the available interaction space for mobile devices; however, there is currently no way to simultaneously track a user's input and provide haptic feedback at the tracked point away from the device. We present Magnetips, a simple, mobile solution for around-device tracking and mid...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
175115
New electro-mechanic access system with dematerialized keys for residential market
OKIDOKEYS is a new system to unlock your home or garage door by using a smartphone or other several devices. The system will allow the user to install it in a few minutes with no need of changing the door lock. The system interacts with both an Okidokeys app-enabled smartphone (iOS and Android) as well as a number of d...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1039/c3nr06899d
1-Dimensional AgVO3 nanowires hybrid with 2-dimensional graphene nanosheets to create 3-dimensional composite aerogels and their improved electrochemical properties
3D porous AgVO3 nanowires/graphene composite aerogels show high electrical conductivity, high mechanical flexibility, and good electrochemical performance for lithium ion storage.
[ "Condensed Matter Physics", "Materials Engineering" ]
W2370116891
Consideration on the Issues of the Balanced Budget Multiplier in the Proportional Tax System
The scholars have put forward their own opinions about whether the balanced budget multiplier should be less than 1 or equal to 1 in proportional tax system.The main divarication is resulted from the different understanding of in the statement of definition of the balanced budget multiplier on the same time variation o...
[ "Individuals, Markets and Organisations" ]
10.1039/c7cc03469e
To cage or to be caged? The cytotoxic species in ruthenium-based photoactivated chemotherapy is not always the metal
In metal-based photoactivated chemotherapy (PACT), two photoproducts are generated by light-triggered photosubstitution of a metal-bound ligand: the free ligand itself and an aquated metal complex.
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
W2325828815
Growth of Nanosized Calcite through Gas−Solid Carbonation of Nanosized Portlandite under Anisobaric Conditions
The gas−solid carbonation of nanosized portlandite was experimentally investigated using a static bed reactor under anisobaric conditions. The effects of initial CO2 pressure (10−40 bar), reaction temperature (30 and 60 °C), and relative humidity were investigated. Three steps of the carbonation process were determined...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Materials Engineering" ]
10.1103/PhysRevD.87.041501
Self-force as a cosmic censor
We examine Hubeny's scenario according to which a near-extremal Reissner-Nordström black hole can absorb a charged particle and be driven toward an over-extremal state in which the charge exceeds the mass, signaling the destruction of the black hole. Our analysis incorporates the particle's electromagnetic self-force a...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
894350
Taming the particle transport in magnetized plasmas via perturbative fields
Wave-particle interactions are ubiquitous in nature and play a fundamental role in astrophysical and fusion plasmas. In solar plasmas, magnetohydrodynamic (MHD) fluctuations are thought to be responsible for the heating of the solar corona and the generation of the solar wind. In magnetically confined fusion (MCF) devi...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
10.1038/ncomms13167
Thermally enhanced photoluminescence for heat harvesting in photovoltaics
The maximal Shockley-Queisser efficiency limit of 41% for single-junction photovoltaics is primarily caused by heat dissipation following energetic-photon absorption. Solar-Thermophotovoltaics concepts attempt to harvest this heat loss, but the required high temperatures (T>2,000 K) hinder device realization. Conversel...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.12688/wellcomeopenres.10567.1
Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing them
Mendelian randomization (MR), the use of genetic variants as instrumental variables (IVs) to test causal effects, is increasingly used in aetiological epidemiology. Few of the methodological developments in MR have considered the specific situation of using genetic IVs to test the causal effect of exposures in pregnant...
[ "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1021/jacs.6b13072
Higher Order Constitutional Dynamic Networks: [2×3] and [3×3] Networks Displaying Multiple, Synergistic and Competitive Hierarchical Adaptation
The present study investigates the constitutional dynamic networks (CDNs) underlying dynamic covalent libraries (DCLs) that extend beyond the [2×2] case toward higher orders, namely [2×3] and [3×3] CDNs involving respectively six and nine constituents generated from the recombination of five and six components linked t...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
US 201816168237 A
Display apparatus with a crack detection line
A display apparatus includes a substrate including a display area where a plurality of pixels are provided and a non-display area surrounding the display area, an encapsulation layer including an inorganic layer and an organic layer and covering the display area, a dam disposed in the non-display area to surround the d...
[ "Materials Engineering", "Systems and Communication Engineering" ]
10.1016/j.neuron.2019.05.022
Cerebellar Contribution to Preparatory Activity in Motor Neocortex
In motor neocortex, preparatory activity predictive of specific movements is maintained by a positive feedback loop with the thalamus. Motor thalamus receives excitatory input from the cerebellum, which learns to generate predictive signals for motor control. The contribution of this pathway to neocortical preparatory ...
[ "Neuroscience and Disorders of the Nervous System", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1038/s41477-017-0039-z
Arabidopsis BTB/POZ protein-dependent PENETRATION3 trafficking and disease susceptibility
The outermost cell layer of plant roots (epidermis) constantly encounters environmental challenges. The epidermal outer plasma membrane domain harbours the PENETRATION3 (PEN3)/ABCG36/PDR8 ATP-binding cassette transporter that confers non-host resistance to several pathogens. Here, we show that the Arabidopsis ENDOPLASM...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
W2007465676
Tantalum and vanadium response to shock-wave loading at normal and elevated temperatures. Non-monotonous decay of the elastic wave in vanadium
The evolution of the elastic precursor waves in pure tantalum and vanadium is presented at normal and elevated temperatures over propagation distances that ranged from 0.125 to 3 mm. Measurements were performed in order to obtain experimental data about the temperature-rate dependence of the yield stress of the two met...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1063/1.5141384
Optimization Of Pulses With Low Bandwidth For Improved Excitation Of Multiple Quantum Coherences In Nmr Of Quadrupolar Nuclei
We discuss the commonly encountered problem when optimizing NMR pulses using optimal control that the otherwise very precise NMR theory does not provide as excellent agreement with experiments. We hypothesize that this disagreement is due to phase transients in the pulse due to abrupt phase- and amplitude changes resul...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1007/s11357-012-9445-3
Interactive effects of sex, social environment, dietary restriction, and methionine on survival and reproduction in fruit flies
For the evolution of life histories, the trade-off between survival and reproduction is fundamental. Because sexes optimize fitness in different ways, this trade-off is expected to be resolved differently by males and females. Consequently, the sexes are predicted to respond differently to changes in resource availabil...
[ "Environmental Biology, Ecology and Evolution", "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1088/1475-7516/2013/10/019
Tools For Model Independent Bounds In Direct Dark Matter Searches
We discuss a framework (based on non-relativistic operators) and a self-contained set of numerical tools to derive the bounds from some current direct detection experiments on virtually any arbitrary model of Dark Matter elastically scattering on nuclei.
[ "Fundamental Constituents of Matter", "Computer Science and Informatics" ]
10.1016/j.tplants.2009.01.006
A morphogenetic trigger: is there an emerging concept in plant developmental biology?
Morphogens are involved in the establishment of positional information that is essential for pattern formation. In plants, the phytohormone auxin displays some characteristics of a morphogen. Gradients of auxin distribution are required for tissue patterning within the embryo and the root apex. In some other instances,...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1039/C8SM00112J
Free Standing Three Dimensional Hollow Bacterial Cellulose Structures With Controlled Geometry Via Patterned Superhydrophobic Hydrophilic Surfaces
Bacteria can produce cellulose, one of the most abundant biopolymer on earth, and emerge as an interesting candidate to fabricate advanced materials. Cellulose produced by Komagataeibacter Xylinus, a bacterial strain, is a pure water insoluble biopolymer, without hemicellulose or lignin. Bacterial cellulose (BC) exhibi...
[ "Materials Engineering", "Synthetic Chemistry and Materials", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.2140/ant.2017.11.213
Logarithmic good reduction, monodromy and the rational volume
Let R be a strictly local ring complete for a discrete valuation, with fraction field K and residue field of characteristic p > 0. Let X be a smooth, proper variety over K. Nicaise conjectured that the rational volume of X is equal to the trace of the tame monodromy operator on l-adic cohomology if X is cohomologicall...
[ "Mathematics" ]
10.3791/58167
Covalent Immobilization Of Proteins For The Single Molecule Force Spectroscopy
In recent years, atomic force microscopy (AFM) based single molecule force spectroscopy (SMFS) extended our understanding of molecular properties and functions. It gave us the opportunity to explore a multiplicity of biophysical mechanisms, e. g. , how bacterial adhesins bind to host surface receptors in more detail. A...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
W2549824732
Taddeo di Bartolo e Rinaldo Brancaccio a Roma: Santa Maria in Trastevere e Santa Maria Maggiore
Taddeo di Bartolo and Rinaldo Brancaccio in Rome: Santa Maria in Trastevere and Santa Maria Maggiore. The paper reassesses the late career of Taddeo di Bartolo (d. 1422), the most illustrious Sienese painter of the time. By close analysis of a damaged and hardly known fresco formerly in an external tabernacle at Santa ...
[ "Texts and Concepts", "The Study of the Human Past", "Studies of Cultures and Arts" ]
259530
Communication and Computation - Two Sides of One Tapestry
Networks have been studied in depth for several decades, but one aspect has received little attention: Interference. Most networks use clever algorithms to avoid interference, and this strategy has proved effective for traditional supply-chain or wired communication networks. However, the emergence of wireless networks...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1093/oso/9780190465544.003.0010
From Hate to Political Solidarity
Hate is currently enjoying the status of summum malum within the common sense of constitutional democracies. Hateful acts are criminalized and hate speech tests the limits of our commitment to free expression. This chapter shifts focus away from hate speech and crime and toward the structural conditions that normalize ...
[ "The Social World and Its Interactions", "Institutions, Governance and Legal Systems", "Texts and Concepts" ]
10.1109/ICDMW.2018.00022
Blockpki An Automated Resilient And Transparent Public Key Infrastructure
This paper describes BlockPKI, a blockchain-based public-key infrastructure that enables an automated, resilient, and transparent issuance of digital certificates. Our goal is to address several shortcomings of the current TLS infrastructure and its proposed extensions. In particular, we aim at reducing the power of in...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
IL 2010000609 W
AN OBJECT ATTACHER AND A METHOD FOR ATTACHING A MOVABLE OBJECT
In one aspect, the present invention is directed to an object attacher (10) comprising: an object's magnet (14) fixed to a movable object (28) moving the object's magnet along a course (24); a first stationary magnet (18) polarized similar to the object's magnet (14) for repulsing thereof, the first stationary magnet (...
[ "Products and Processes Engineering", "Materials Engineering" ]
W2272945869
A study of quality teaching in the Secondary Schools of Karachi
The present study aimed at finding out the factors affecting the quality teaching at the secondary level. Moreover, this study examined the existing academic and administrative state of schools, how they are supervised, and how they can be made effective to provide quality teaching. The population of the study comprise...
[ "The Social World and Its Interactions" ]
10.1039/c7sm00690j
Dynamical theory of the inverted cheerios effect
Recent experiments have shown that liquid drops on highly deformable substrates exhibit mutual interactions. This is similar to the Cheerios effect, the capillary interaction of solid particles at a liquid interface, but now the roles of solid and liquid are reversed. Here we present a dynamical theory for this inverte...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
10.1038/s41467-019-11121-z
Pioneer and repressive functions of p63 during zebrafish embryonic ectoderm specification
The transcription factor p63 is a master regulator of ectoderm development. Although previous studies show that p63 triggers epidermal differentiation in vitro, the roles of p63 in developing embryos remain poorly understood. Here, we use zebrafish embryos to analyze in vivo how p63 regulates gene expression during dev...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2954171506
Evolving stellar models to find the origins of our galaxy
After the Big Bang, it took about 200 million years before the very first stars would form - now more than 13 billion years ago. Unfortunately, we will not be able to observe these stars directly. Instead, we can observe the 'fossil' records that these stars have left behind, preserved in the oldest stars of our own ga...
[ "Universe Sciences", "Computer Science and Informatics" ]
US 77190104 A
Methods and apparatuses for selectively disabling functionality of a device
In one embodiment, the methods and apparatuses for selectively disabling functionality of a device detect a device; detect a device type of the device; and transmit a signal to the device for selectively disabling a function of the device based on the device type.
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]