id stringlengths 6 42 | title stringlengths 3 499 | abstract stringlengths 0 6.24k | label listlengths 0 6 |
|---|---|---|---|
10.1002/2016JB013824 | Vaporization Of Fault Water During Seismic Slip | Laboratory and numerical studies, as well as field observations, indicate that phase transitions of pore water might be an important process in large earthquakes. We present a model of the thermo-hydro-chemo-mechanical processes, including a two-phase mixture model to incorporate the phase transitions of pore water, oc... | [
"Earth System Science",
"Physical and Analytical Chemical Sciences"
] |
10.1016/j.cell.2016.07.019 | The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity | Methionine-1 (M1)-linked ubiquitin chains regulate the activity of NF-κB, immune homeostasis, and responses to infection. The importance of negative regulators of M1-linked chains in vivo remains poorly understood. Here, we show that the M1-specific deubiquitinase OTULIN is essential for preventing TNF-associated syste... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1002/anie.201510650 | Expanding the landscape of diterpene structural diversity through stereochemically controlled combinatorial biosynthesis | Plant-derived diterpenoids serve as important pharmaceuticals, food additives, and fragrances, yet their low natural abundance and high structural complexity limits their broader industrial utilization. By mimicking the modularity of diterpene biosynthesis in plants, we constructed 51 functional combinations of class I... | [
"Synthetic Chemistry and Materials",
"Biotechnology and Biosystems Engineering"
] |
10.1073/pnas.1424030112 | Evolutionary signals of symbiotic persistence in the legume–rhizobia mutualism | Understanding the origins and evolutionary trajectories of symbiotic partnerships remains a major challenge. Why are some symbioses lost over evolutionary time whereas others become crucial for survival? Here, we use a quantitative trait reconstruction method to characterize different evolutionary stages in the ancient... | [
"Environmental Biology, Ecology and Evolution",
"Integrative Biology: from Genes and Genomes to Systems"
] |
864182 | Protecting the Right to Culture of Persons with Disabilities and Enhancing Cultural Diversity through European Union Law: Exploring New Paths | The right of people with disabilities to participate in cultural life - which encompasses the rights of access to, and to be involved in cultural activities, as well as the recognition of disability identities, such as Deaf culture – has been for long denied. The cultural exclusion of disabled people has engendered the... | [
"Institutions, Governance and Legal Systems",
"Studies of Cultures and Arts"
] |
10.1371/journal.pbio.3000665 | Orange: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons | The correct subcellular distribution of proteins establishes the complex morphology and function of neurons. Fluorescence microscopy techniques are invaluable to investigate subcellular protein distribution, but they suffer from the limited ability to efficiently and reliably label endogenous proteins with fluorescent ... | [
"Neuroscience and Disorders of the Nervous System",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems"
] |
AU 2015/284411 A | Patterned surfaces | The present disclosure provides patterned materials that may be useful in reducing certain negative effects associated with damaged tissue in vivo. The patterned materials can modify the healing process, and may minimize the formation of scar tissue. Such effects can provide inhibition of adhesion between tissues and/o... | [
"Prevention, Diagnosis and Treatment of Human Diseases",
"Materials Engineering"
] |
10.1007/978-4-431-54270-4_26 | Construction of the noncommutative rank I Bergman domain | In this paper we present a harmonic oscillator realization of the most degenerate discrete series representations of the SU(2,1) group and the deformation quantization of the coset space D = SU(2,1)/U(2) with the method of coherent state quantization. This short article is based on a talk given at the 9-th Internationa... | [
"Mathematics"
] |
10.1088/0022-3727/49/29/294003 | Local Charge Measurement Using Off Axis Electron Holography | A model-independent approach based on Gauss' theorem for measuring the local charge in a specimen from an electron-optical phase image recorded using off-axis electron holography was recently proposed. Here, we show that such a charge measurement is reliable when it is applied to determine the total charge enclosed wit... | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences"
] |
10.1038/s41467-019-09799-2 | Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen | The effectiveness of most cancer targeted therapies is short-lived. Tumors often develop resistance that might be overcome with drug combinations. However, the number of possible combinations is vast, necessitating data-driven approaches to find optimal patient-specific treatments. Here we report AstraZeneca’s large dr... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Computer Science and Informatics"
] |
10.1109/TAC.2018.2835380 | K4Sid Large Scale Subspace Identification With Kronecker Modeling | In this paper, we consider the identification of matrix state-space models (MSSM) of the following form: \begin{align*} \mathbf {X}(k+1) &= \mathbf {A}_2 \mathbf {X}(k) \mathbf {A}_1^T + \mathbf {B}_2 \mathbf {U}(k) \mathbf {B}_1^T \\ \mathbf {Y}(k) &= \mathbf {C}_2 \mathbf {X}(k) \mathbf {C}_1^T + \mathbf {E}(k) \end{... | [
"Computer Science and Informatics",
"Mathematics"
] |
10.1086/698431 | Beyond Ethics Conscience Pacifism And The Political In Wartime Britain | The central intervention of this article concerns the contingency of the relationship between ethics and politics. The empirical focus is Second World War Britain, where the refusal to fight was often framed as a conscientious objection. More broadly, one of the central propositions in the anthropology of ethics has be... | [
"Texts and Concepts",
"The Social World and Its Interactions",
"The Study of the Human Past"
] |
10.1016/j.nanoen.2018.12.037 | Surface potential tailoring of PMMA fibers by electrospinning for enhanced triboelectric performance | Triboelectric generators rely on contact-generated surface charge transfer between materials with different electron affinities to convert mechanical energy into useful electricity. The ability to modify the surface chemistry of polymeric materials can therefore lead to significant enhancement of the triboelectric perf... | [
"Materials Engineering",
"Synthetic Chemistry and Materials",
"Physical and Analytical Chemical Sciences"
] |
10.1126/science.1248725 | Structure of the mitochondrial translocator protein in complex with a diagnostic ligand | The 18-kilodalton translocator protein TSPO is found in mitochondrial membranes and mediates the import of cholesterol and porphyrins into mitochondria. In line with the role of TSPO in mitochondrial function, TSPO ligands are used for a variety of diagnostic and therapeutic applications in animals and humans. We prese... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physical and Analytical Chemical Sciences",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1002/hbm.22787 | Immediate memory for "when, where and what": Short-delay retrieval using dynamic naturalistic material | We investigated the neural correlates supporting three kinds of memory judgments after very short delays using naturalistic material. In two functional magnetic resonance imaging (fMRI) experiments, subjects watched short movie clips, and after a short retention (1. 5-2. 5 s), made mnemonic judgments about specific asp... | [
"Neuroscience and Disorders of the Nervous System"
] |
10.1038/s41467-020-16496-y | Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation | AbstractLymphatic malformations (LMs) are debilitating vascular anomalies presenting with large cysts (macrocystic) or lesions that infiltrate tissues (microcystic). Cellular mechanisms underlying LM pathology are poorly understood. Here we show that the somatic PIK3CAH1047R mutation, resulting in constitutive activati... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physiology in Health, Disease and Ageing"
] |
10.1007/978-3-319-33628-2_18 | Local Food Systems And Their Climate Impacts A Life Cycle Perspective | The creation and maintenance of local food sovereignty and security is a top priority on political agendas. Food systems are characterized by complex dynamic nexuses at different levels and scales, and sustainability assessments necessarily need to approach social, economic, and environmental dimensions. While the prov... | [
"Earth System Science",
"Environmental Biology, Ecology and Evolution"
] |
US 68180601 A | Light-emitting diode (LED) package and packaging method for shaping the external light intensity distribution | An LED package (10) includes LED die (12) mounted onto lead frame (14) and electrically connected thereto whereby LED die (12) is electrically energized through leads (16, 18). An encapsulant (20), preferably an epoxy resin, encapsulates and preferably hermetically seals LED die (12). Encapsulant (20) includes depressi... | [
"Systems and Communication Engineering",
"Materials Engineering"
] |
10.1109/IECON.2016.7793426 | Power Hardware In Loop Harmonic Analysis Of A Smart Transformer Fed Distribution Grid | The Smart Transformer (ST) offers ancillary services in the low voltage grids. These new services in a real distribution grid can be demonstrated by means of simulation software, but it is difficult to prove them in lab due to the complexity and heterogeneity of the distribution grids. The Power-Hardware-In-Loop (PHIL)... | [
"Systems and Communication Engineering",
"Products and Processes Engineering"
] |
W2561691587 | FOREIGN DIRECT INVESTMENT AND TECHNOLOGICAL INNOVATION IN DEVELOPING COUNTRIES | A large number of countries have enacted laws aimed at making it easier for firms to invest in their country, while many countries offer various monetary incentives and tax incentives to encourage inward Foreign Direct Investment (FDI). The desire to attract FDI is due not only to the fact that FDI brings in new invest... | [
"Individuals, Markets and Organisations",
"Institutions, Governance and Legal Systems"
] |
10.1016/j.tins.2017.03.002 | The Role of Mental Maps in Decision-Making | A growing body of work is investigating the use of mental maps during decision-making. Here we discuss how decision-making organizes experiences according to an internal model of the current task, thereby structuring memory. Likewise, we consider how the structure of mental maps contributes to decision-making. | [
"The Human Mind and Its Complexity"
] |
10.1523/JNEUROSCI.4228-15.2016 | Reduced Efficacy Of The Kcc2 Cotransporter Promotes Epileptic Oscillations In A Subiculum Network Model | Pharmacoresistant epilepsy is a chronic neurological condition in which a basal brain hyperexcitability results in paroxysmal hypersynchronous neuronal discharges. Human temporal lobe epilepsy has been associated with dysfunction or loss of the potassium-chloride cotransporter KCC2 in a subset of pyramidal cells in the... | [
"Neuroscience and Disorders of the Nervous System",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Computer Science and Informatics"
] |
10.1016/j.bbapap.2019.140335 | Characterization of pyranose oxidase variants for bioelectrocatalytic applications | Pyranose oxidase (POx) catalyzes the oxidation of D-glucose to 2-ketoglucose with concurrent reduction of oxygen to H2O2. POx from Trametes ochracea (ToPOx) is known to react with alternative electron acceptors including 1,4-benzoquinone (1,4-BQ), 2,6-dichlorophenol indophenol (DCPIP), and the ferrocenium ion. In this ... | [
"Physical and Analytical Chemical Sciences",
"Biotechnology and Biosystems Engineering"
] |
10.1016/j.anbehav.2020.04.006 | How do backward-walking ants (Cataglyphis velox) cope with navigational uncertainty? | Current opinion in insect navigation assumes that animals need to align with the goal direction to recognize familiar views and approach it. Yet, ants sometimes drag heavy food items backwards to the nest and it is still unclear to what extent they rely on visual memories while doing so. In this study displacement expe... | [
"Integrative Biology: from Genes and Genomes to Systems",
"Environmental Biology, Ecology and Evolution"
] |
interreg_1073 | CROSS-BORDER EDUCATION NETWORK 4.0 | The Industrial revolution n4is on progress: Schools, Universities and SMEs are fully involved to provide necessary skills and innovation processes. The Alpine Area is involved and several local and EU actions are addressing this challenging topic. The transboarder area interested by E-EDU4.0 is on this topic with assis... | [
"Products and Processes Engineering",
"Computer Science and Informatics",
"The Social World and Its Interactions"
] |
10.1093/cid/ciy938 | The importance of heterogeneity to the epidemiology of tuberculosis | Although less well-recognized than for other infectious diseases, heterogeneity is a defining feature of tuberculosis (TB) epidemiology. To advance toward TB elimination, this heterogeneity must be better understood and addressed. Drivers of heterogeneity in TB epidemiology act at the level of the infectious host, orga... | [
"Environmental Biology, Ecology and Evolution",
"Immunity, Infection and Immunotherapy",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1007/JHEP09(2011)050 | Lifting Asymptotic Degeneracies With The Mirror Tba | We describe a qualitative feature of the AdS_5 x S^5 string spectrum which is not captured by the asymptotic Bethe ansatz. This is reflected by an enhanced discrete symmetry in the asymptotic limit, whereby extra energy degeneracy enters the spectrum. We discuss how finite size corrections should lift this degeneracy, ... | [
"Fundamental Constituents of Matter",
"Mathematics"
] |
10.1007/s12678-016-0340-z | Pt Nanoparticles Supported on Niobium-Doped Tin Dioxide: Impact of the Support Morphology on Pt Utilization and Electrocatalytic Activity | Two synthesis routes were used to design high surface area niobium-doped tin dioxide (Nb-doped SnO2, NTO) nanostructures with either loose-tube (fibre-in-tube) morphology using electrospinning or aerogel morphology using a sol-gel process. A higher specific surface area but a lower apparent electrical conductivity was ... | [
"Physical and Analytical Chemical Sciences",
"Condensed Matter Physics",
"Materials Engineering"
] |
W4220954082 | CNN-LSTM: An efficient hybrid deep learning architecture for predicting short-term photovoltaic power production | Climate change is pushing an increasing number of nations to use green energy resources, particularly solar power as an applicable substitute to traditional power sources. However, photovoltaic power generation is highly weather-dependent, relying mostly on solar irradiation that is highly unstable, and unpredictable w... | [
"Systems and Communication Engineering",
"Computer Science and Informatics"
] |
172260 | Evolution of fungal mating-type chromosomes | Sex chromosomes often show extensive areas of suppressed recombination and cytological differentiation, a well-documented phenomenon in animals and plants. Lack of recombination is expected to limit the efficacy of natural selection, leading to degeneration in gene content. Similarly, fungal mating-type chromosomes, wh... | [
"Integrative Biology: from Genes and Genomes to Systems",
"Environmental Biology, Ecology and Evolution",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1016/j.aop.2020.168125 | The unreasonable effectiveness of Eliashberg theory for pairing of non-Fermi liquids | The paradigmatic Migdal–Eliashberg theory of the electron–phonon problem is central to the understanding of superconductivity in conventional metals. This powerful framework is justified by the smallness of the Debye frequency relative to the Fermi energy, and allows an enormous simplification of the full many-body pro... | [
"Condensed Matter Physics"
] |
W1969419593 | Effects of acidic conditions on the physiology of a green alga (Micractiniumsp.) before and after a 5-year interaction withTetrahymena thermophilain an experimental microcosm | The mechanisms through which algae evolve physiological characteristics related to endosymbiotic associations with heterotrophic organisms remain unclear. We previously showed that a green alga (Micractinium sp.) was able to evolve a host (ciliate)-benefiting phenotype that prolonged the longevity of Tetrahymena thermo... | [
"Environmental Biology, Ecology and Evolution",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1073/pnas.1712530114 | DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line | Meiotic synapsis and recombination between homologs permits the formation of cross-overs that are essential for generating chromosomally balanced sperm and eggs. In mammals, surveillance mechanisms eliminate meiotic cells with defective synapsis, thereby minimizing transmission of aneuploidy. One such surveillance mech... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1007/s00445-016-1006-7 | Conduit margin heating and deformation during the AD 1886 basaltic Plinian eruption at Tarawera volcano, New Zealand | During explosive eruptions, a suspension of gas and pyroclasts rises rapidly within a conduit. Here, we have analysed textures preserved in the walls of a pyroclastic feeder dyke of the AD 1886 Tarawera basaltic Plinian fissure eruption. The samples examined consist of basaltic ash and scoria plastered onto a conduit w... | [
"Earth System Science",
"Materials Engineering",
"Physical and Analytical Chemical Sciences"
] |
US 17190793 A | Non-invasive method for in-vivo bone-growth stimulation | A method and apparatus for preventing osteopenia, promoting bone tissue growth, ingrowth, and healing of bone tissue includes the step of and means for applying a mechanical load to the bone tissue at a relatively low level on the order of between about 50 and about 500 microstrain, peak-to-peak, and at a relatively hi... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
10.3389/fnbeh.2015.00167 | Evidence from a rare case study for hebbian-like changes in structural connectivity induced by long-term deep brain stimulation | It is unclear whether Hebbian-like learning occurs at the level of long-range white matter connections in humans, i. e. , where measurable changes in structural connectivity (SC) are correlated with changes in functional connectivity. However, the behavioral changes observed after deep brain stimulation (DBS) suggest t... | [
"Neuroscience and Disorders of the Nervous System",
"Computer Science and Informatics"
] |
10.1016/j.cell.2019.05.010 | The Translational Landscape of the Human Heart | Gene expression in human tissue has primarily been studied on the transcriptional level, largely neglecting translational regulation. Here, we analyze the translatomes of 80 human hearts to identify new translation events and quantify the effect of translational regulation. We show extensive translational control of ca... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Physiology in Health, Disease and Ageing"
] |
10.1051/0004-6361/201834086 | Broadening Of The Dem By Multi Shelled And Turbulent Loops | Broad differential emission measure (DEM) distributions in the corona are a sign of multi-thermal plasma along the line-of-sight. Traditionally, this is interpreted as evidence of multi-stranded loops. Recently, however, it has been shown that multi-stranded loops are unlikely to exist in the solar corona, because of t... | [
"Universe Sciences",
"Fundamental Constituents of Matter"
] |
10.1016/j.bpj.2015.01.029 | Revisiting the interaction between the chaperone skp and lipopolysaccharide | The bacterial outer membrane comprises two main classes of components, lipids and membrane proteins. These nonsoluble compounds are conveyed across the aqueous periplasm along specific molecular transport routes: the lipid lipopolysaccharide (LPS) is shuttled by the Lpt system, whereas outer membrane proteins (Omps) ar... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physical and Analytical Chemical Sciences"
] |
W2114835337 | Prevalence of labyrinthine ossification in CT and MR imaging of patients with acute deafness to severe sensorineural hearing loss | To evaluate the prevalence of labyrinthine ossification, and especially cochlear ossification, in a cohort of patients with unilateral sudden deafness or severe sensorineural hearing loss.Retrospective data collection.Sixty-four consecutive patients with unilateral sudden deafness or severe sensorineural hearing loss a... | [
"Prevention, Diagnosis and Treatment of Human Diseases",
"Neuroscience and Disorders of the Nervous System"
] |
EP 2017072407 W | IMPROVED METHOD FOR DYEING TEXTILES CONTAINING SYNTHETIC MATERIALS IN THE WASHING MACHINE USING MODIFIED SILICONES | The present invention relates to a method for machine-dyeing textiles, more particularly textiles which contain synthetic materials such as polyester. | [
"Products and Processes Engineering",
"Materials Engineering"
] |
W2188489921 | Topographic surveys at the SDT km6 farm, Buasvm Timisoara, Romania (Timisoara-Arad NR). | This paper aims at presenting the topographic surveys on the Didactic Station Farm of Timisoara, Romania, at the km 6, on the Timisoara-Arad NR. The farm belongs to the Commune of Dumbravita; it has the cadastral number CC49 and it consists, according to the Land Cadastre (no. 4631) of agricultural and zootechnic admin... | [
"Earth System Science",
"Systems and Communication Engineering"
] |
W2903531556 | Assuming Direct Control: The Beguiling Allure of Incomes Policies in Postwar America | Abstract: Histories of American economic policymaking after World War II often describe a “Fiscal Revolution,” in which Keynesian macroeconomic tools replaced the microeconomic regulations and reforms of the New Deal. This article challenges that narrative by demonstrating how the Keynesian economists responsible for t... | [
"Individuals, Markets and Organisations",
"The Study of the Human Past",
"Institutions, Governance and Legal Systems"
] |
10.1007/JHEP12(2016)079 | Improved jet substructure methods: Y-splitter and variants with grooming | It has recently been demonstrated with Monte Carlo studies that combining the well-known Y-splitter and trimming techniques gives rise to important gains in the signal significance achievable for boosted electroweak boson tagging at high pt. Here we carry out analytical calculations that explain these findings from fir... | [
"Fundamental Constituents of Matter"
] |
896138 | Next generation of mechanics with hazard-responsive surface | 80%+ of failures in machines using lubricated moving parts (bearings, gears, camshafts etc.) is due to the damaging operational condition called starved oil lubrication. Recurrent exposure to this state is the bottleneck of performance and durability for such machinery. End-users are happy to pay more for reliable and ... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
W1600703341 | Sharpening Bounds on Principal Effects with Covariates | Estimation of treatment effects in randomized studies is often hampered by possible selection bias induced by conditioning on or adjusting for a variable measured post-randomization. One approach to obviate such selection bias is to consider inference about treatment effects within principal strata, that is, principal ... | [
"Mathematics",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.5194/se-11-1275-2020 | Mantle flow below the central and greater Alpine region: Insights from SKS anisotropy analysis at AlpArray and permanent stations | The Alpine chain in western and central Europe is a complex orogen developed as a result of the African-Adriatic plate convergence towards the European continent and the closure of several Tethys oceanic branches. Seismic tomography studies detected high-wave-speed slabs plunging beneath the orogen to variable depths a... | [
"Earth System Science"
] |
949899 | Verified physics-aware machine learning to transform non-linear power system stability and optimization | Measures against global warming require disruptive changes in the electricity sector. Drastically reducing CO2 emissions involves replacing bulk generation units with millions of renewable energy sources, along with a rapid increase of electricity demand. Maintaining the stability of the system with current approaches ... | [
"Computer Science and Informatics",
"Systems and Communication Engineering",
"Products and Processes Engineering"
] |
10.1074/jbc.M114.549980 | Rabies virus envelope glycoprotein targets lentiviral vectors to the axonal retrograde pathway in motor neurons | Rabies pseudotyped lentiviral vectors have great potential in gene therapy, not least because of their ability to transduce neurons following their distal axonal application. However, very little is known about the molecular processes that underlie their retrograde transport and cell transduction. Using multiple labeli... | [
"Neuroscience and Disorders of the Nervous System",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
SE 9801193 W | METHOD AND ARRANGEMENT FOR COMPOSTING BIODEGRADABLE MATERIAL | Arrangement for collecting and composting night-soil and other biodegradable material, comprising a space (23) in which a starting bed (29) has been spread out in order to accelerate the breakdown of material (30) which is dropped down onto the starting bed. The space (23) is lined with an inner layer of a flexible, li... | [
"Products and Processes Engineering",
"Environmental Biology, Ecology and Evolution"
] |
10.1016/j.neuron.2020.08.016 | The Sound of Silence: Hidden Responses of Neural Circuits to Alzheimer-Linked Mutations | Dysfunctions of cortico-hippocampal circuits represent a hallmark of Alzheimer's disease. In this issue of Neuron, Jun et al. illuminate the spatial coding failures by familial Alzheimer's disease mutations that may underlie the progressive decline in spatial mnemonic processing. | [
"Neuroscience and Disorders of the Nervous System",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1103/PhysRevFluids.3.084002 | Wetting over pre-existing liquid films | Wetting of a liquid over another, pre-existing liquid film governs several natural phenomena and technical applications, such as coating and oil recovery. The dynamics of this everyday process are poorly understood due to the lack of space and time-resolved techniques, which can discriminate between the two liquids. He... | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences"
] |
10.1021/ja303309e | Release of high-energy water as an essential driving force for the high-affinity binding of cucurbit[n]urils | Molecular dynamics simulations and isothermal titration calorimetry (ITC) experiments with neutral guests illustrate that the release of high-energy water from the cavity of cucurbit[n]uril (CBn) macrocycles is a major determinant for guest binding in aqueous solutions. The energy of the individual encapsulated water m... | [
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
10.1209/0295-5075/114/26005 | Analog Simulation Of Weyl Particles With Cold Atoms | In this letter we report on a novel approach to study the dynamics of harmonically confined Weyl particles using magnetically trapped fermionic atoms. We find that after a kick of its center of mass, the system relaxes towards a steady state even in the absence of interactions, in stark contrast with massive particles ... | [
"Condensed Matter Physics",
"Fundamental Constituents of Matter"
] |
3729137 | Scalable structured micro illumination light engines | The SMILE idea is based on the results of FET-Open “ChipScope”, which gave us unique technology skills in the processing of nanoLED arrays. In contrast to the ChipScope’s nanoLEDs for superresolution microscopy, larger SMILE microLEDs arrays can also be used for activating and manipulating chemical or biological reacti... | [
"Systems and Communication Engineering",
"Condensed Matter Physics",
"Materials Engineering",
"Physical and Analytical Chemical Sciences",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1038/s41586-018-0045-y | Earthquake-induced transformation of the lower crust | The structural and metamorphic evolution of the lower crust has direct effects on the lithospheric response to plate tectonic processes involved in orogeny, including subsidence of sedimentary basins, stability of deep mountain roots and extension of high-topography regions. Recent research shows that before orogeny mo... | [
"Earth System Science"
] |
10.1002/bit.25562 | An optogenetic upgrade for the Tet-OFF system | The rapid development of mammalian optogenetics has produced an expanding number of gene switches that can be controlled with the unprecedented spatiotemporal resolution of light. However, in the "pre-optogenetic" era many networks, cell lines and transgenic organisms have been engineered that rely on chemically-induci... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Cell Biology, Development, Stem Cells and Regeneration",
"Physical and Analytical Chemical Sciences"
] |
171527 | Enhanced satellite laser ranging system | The EO-SLR is a next generation satellite laser ranging system that incorporates latest advances in the field to assure ease of setup, use and sustainable economic operation. Packaged in standard sea container with modular design for laser systems, climate control, calibration equipment, data systems, and power systems... | [
"Products and Processes Engineering",
"Systems and Communication Engineering",
"Universe Sciences"
] |
10.1029/2011JB008801 | Slow Slip Events And Strain Accumulation In The Guerrero Gap Mexico | [1] Global positioning system (GPS) time series in Guerrero (Mexico) reveal the existence of large slow slip events (SSEs) at the boundary between the Cocos and North American plates. In this study, we examined the last three SSEs that occurred in 2001/2002, 2006 and 2009/2010, and their impact on the strain accumulati... | [
"Earth System Science"
] |
interreg_1183 | EMAS as a Nest to Help And Nurture the Circular Economy | Organizations, large and Small and Medium sized enterprises (SMEs),are increasingly aware of the benefits of closing loops by improving resource efficiency: saving material costs, creating competitive advantages and new markets are among the main reasons for organisations to take action.At this respect, the EcoManageme... | [
"Products and Processes Engineering",
"Individuals, Markets and Organisations",
"Institutions, Governance and Legal Systems"
] |
10.1098/rspb.2014.1622 | Evolution of cultural traits occurs at similar relative rates in different world regions | A fundamental issue in understanding human diversity is whether or not there are regular patterns and processes involved in cultural change. Theoretical and mathematical models of cultural evolution have been developed and are increasingly being used and assessed in empirical analyses. Here, we test the hypothesis that... | [
"Environmental Biology, Ecology and Evolution",
"The Social World and Its Interactions",
"The Study of the Human Past"
] |
10.1144/M39.1 | Chapter 1 An Overview Of The Eruption Of Soufriere Hills Volcano Montserrat From 2000 To 2010 | Abstract The 1995–present eruption of Soufriere Hills Volcano on Montserrat has produced over a cubic kilometre of andesitic magma, creating a series of lava domes that were successively destroyed, with much of their mass deposited in the sea. There have been five phases of lava extrusion to form these lava domes: Nove... | [
"Earth System Science",
"Products and Processes Engineering"
] |
10.5194/acp-12-9977-2012 | Impact of HONO on global atmospheric chemistry calculated with an empirical parameterization in the EMAC model | The photolysis of HONO is important for the atmospheric HO x (OH + HO 2) radical budget and ozone formation, especially in polluted air. Nevertheless, owing to the incomplete knowledge of HONO sources, realistic HONO mechanisms have not yet been implemented in global models. We investigated measurement data sets from 1... | [
"Physical and Analytical Chemical Sciences",
"Earth System Science"
] |
W2022700714 | Demographic Situation and the Level of Human Development of the Republic of Kazakhstan: Regional Aspects | Demographic Situation and the Level of Human Development of the Republic of Kazakhstan: Regional Aspects The objects of research are indicators of human development in Kazakhstan from the moment of independence acquisition by the republic until today. The subject of scientific research is spatial-existential patterns o... | [
"Human Mobility, Environment, and Space",
"The Social World and Its Interactions"
] |
US 202117236007 A | CHARGED PARTICLE BEAM WRITING APPARATUS, CHARGED PARTICLE BEAM WRITING METHOD, AND A NON-TRANSITORY COMPUTER-READABLE STORAGE MEDIUM | Position shifts caused by charging phenomena can be corrected with high accuracy. A charged particle beam writing apparatus includes an exposure-amount distribution calculator calculating an exposure amount distribution of a charged particle beam using a pattern density distribution and a dose distribution, a fogging c... | [
"Physical and Analytical Chemical Sciences",
"Systems and Communication Engineering"
] |
10.1101/207571 | Pseudo Dollo Models For The Evolution Of Binary Characters Along A Tree | The stochastic Dollo model is a model for capturing evolution of features, for example cognate data in language evolution. However, it is rather sensitive to borrowing events, coding errors, semantic shift and other anomalies, so other models, in particular the covarion model, tends to have a better fit to the data. He... | [
"Mathematics",
"Computer Science and Informatics"
] |
10.3390/catal9070567 | P450BM3-Catalyzed Oxidations Employing Dual Functional Small Molecules | A set of dual functional small molecules (DFSMs) containing different amino acids has been synthesized and employed together with three different variants of the cytochrome P450 monooxygenase P450BM3 from Bacillus megaterium in H2O2-dependent oxidation reactions. These DFSMs enhance P450BM3 activity with hydrogen perox... | [
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
10.1021/acs.nanolett.7b04227 | Affinity Purification and Single-Molecule Analysis of Integral Membrane Proteins from Crude Cell-Membrane Preparations | The function of integral membrane proteins is critically dependent on their naturally surrounding lipid membrane. Detergent-solubilized and purified membrane proteins are therefore often reconstituted into cell-membrane mimics and analyzed for their function with single-molecule microscopy. Expansion of this approach t... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physical and Analytical Chemical Sciences",
"Materials Engineering"
] |
10.1007/JHEP01(2018)035 | Quantum Gravity From Conformal Field Theory | We bootstrap loop corrections to AdS5 supergravity amplitudes by enforcing the consistency of the known classical results with the operator product expansion of $$ \mathcal{N} $$
= 4 super Yang-Mills theory. In particular this yields much new information on the spectrum of double-trace operators which can then be used... | [
"Fundamental Constituents of Matter",
"Mathematics"
] |
818943 | Deciphering the metabolic roles of the urea-cycle pathway in carcinogenesis for improving diagnosis and therapy | Almost 100 years ago, Warburg described a metabolic change in energy flux that occurs during carcinogenesis. Since then, multiple studies have demonstrated how anabolic synthesis of macromolecules can be altered to support cancer cell progression. Yet, the potential effect of altered catabolic degradation of macromolec... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physiology in Health, Disease and Ageing",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
interreg_3049 | Storm ALEX impact response | The storm Alex is a serious event that has put a strain on the entire territory ALCOTRA, without administrative boundaries between states and without natural barriers as can be the Alps.
This hostile circumstance urges us to gather our strength and act collectively on climate change.
It is necessary to prepare the te... | [
"Products and Processes Engineering",
"Earth System Science"
] |
10.1103/PhysRevLett.115.138301 | Colloidal Microworms Propelling via a Cooperative Hydrodynamic Conveyor Belt | We study propulsion arising from microscopic colloidal rotors dynamically assembled and driven in a viscous fluid upon application of an elliptically polarized rotating magnetic field. Close to a confining plate, the motion of this self-assembled microscopic worm results from the cooperative flow generated by the spinn... | [
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences"
] |
10.3168/jds.2015-10202 | Linking bone development on the caudal aspect of the distal phalanx with lameness during life | Claw horn disruption lesions (CHDL; sole hemorrhage, sole ulcer, and white line disease) cause a large proportion of lameness in dairy cattle, yet their etiopathogenesis remains poorly understood. Untreated CHDL may be associated with damage to the internal anatomy of the foot, including to the caudal aspect of the dis... | [
"Physiology in Health, Disease and Ageing",
"Cell Biology, Development, Stem Cells and Regeneration",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1093/mnras/stz2266 | On the role of supermassive black holes in quenching star formation in local central galaxies | ABSTRACT
We analyse the role of AGN feedback in quenching star formation for massive, central galaxies in the local Universe. In particular, we compare the prediction of two semi-analytic models (l-galaxies and sage) featuring different schemes for AGN feedback, with the SDSS DR7 taking advantage of a novel technique ... | [
"Universe Sciences",
"Computer Science and Informatics"
] |
10.1080/09546553.2019.1668781 | What Do Closed Source Data Tell Us About Lone Actor Terrorist Behavior A Research Note | This article contributes to the growing body of knowledge on lone-actor terrorism with the incorporation of closed-source data. The analyses presented investigate the antecedent behaviors of U. K. -b. . . | [
"The Social World and Its Interactions"
] |
10.1038/s41380-018-0198-y | Sex-specific impact of prenatal androgens on social brain default mode subsystems | AbstractEarly-onset neurodevelopmental conditions (e. g. , autism) affect males more frequently than females. Androgens may play a role in this male-bias by sex-differentially impacting early prenatal brain development, particularly neural circuits that later develop specialized roles in social cognition. Here, we find... | [
"Neuroscience and Disorders of the Nervous System",
"Cell Biology, Development, Stem Cells and Regeneration",
"Integrative Biology: from Genes and Genomes to Systems"
] |
Q4772621 | TRUNCHINI SIMONE | UMA EMPRESA INDIVIDUAL FUNDADA EM 2014 COMO UM SIMPLES MEDIADOR DE SEGUROS COMO COLABORADORA DE VÁRIOS AGENTES E CORRETORES DESDE 2019 TEM UM MANDATO DIRETO DE AGÊNCIA PARA A REPRESENTAÇÃO DA EMPRESA HELVETIA. O OBJETIVO É PROPOR AO CLIENTE UMA SOLUÇÃO COMPLETA E PERSONALIZADA, COM ESPECIAL ATENÇÃO PARA AS EMPRESAS QUE... | [
"Individuals, Markets and Organisations"
] |
172725 | African governance and space: transport corridors, border towns and port cities in transition | AFRIGOS investigates the process of 'respacing' Africa, a political drive towards regional and continental integration, on the one hand, and the re-casting of Africa's engagement with the global economy, on the other. This is reflected in unprecedented levels of investment in physical and communications infrastructure,... | [
"Human Mobility, Environment, and Space",
"Institutions, Governance and Legal Systems"
] |
10.1080/16000889.2018.1471913 | On The Early Studies Recognizing The Role Of Sulphuric Acid In Atmospheric Haze And New Particle Formation | Atmospheric aerosols have been a subject to scientific interest at least since the Age of Enlightenment, including theories concerning the origins of atmospheric haze and dust. Early studies associ. . . | [
"Earth System Science",
"Physical and Analytical Chemical Sciences"
] |
222531 | Overcoming the selectivity challenge in chemistry and chemical biology via innovative tethering strategies | In the last two centuries, synthetic organic chemistry has undergone an unprecedented revolution. The ability to understand and modify the molecular structure of matter has changed our life in many areas, such as medicine, agriculture or commodity materials. These major successes gave the impression that synthetic chem... | [
"Synthetic Chemistry and Materials",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1016/j.cobeha.2015.09.006 | Phasic dopamine signals: From subjective reward value to formal economic utility | Although rewards are physical stimuli and objects, their value for survival and reproduction is subjective. The phasic, neurophysiological and voltammetric dopamine reward prediction error response signals subjective reward value. The signal incorporates crucial reward aspects such as amount, probability, type, risk, d... | [
"Neuroscience and Disorders of the Nervous System",
"Individuals, Markets and Organisations"
] |
10.1038/s41467-017-00249-5 | Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry | Quantitative proteomics employing mass spectrometry is an indispensable tool in life science research. Targeted proteomics has emerged as a powerful approach for reproducible quantification but is limited in the number of proteins quantified. SWATH-mass spectrometry consists of data-independent acquisition and a target... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
222990 | Open ground truth training network : magnetic resonance image simulation for training and validation of image analysis algorithms | This action aims to optimally prepare three young researchers for the evolving medical imaging world by offering a unique set of targeted interdisciplinary training and research assignments in the areas of anatomy, pathology, imaging techniques, quantitative image analysis and segmentation, Magnetic Resonance (MR) phys... | [
"Computer Science and Informatics",
"Prevention, Diagnosis and Treatment of Human Diseases",
"Systems and Communication Engineering"
] |
10.1038/nature09790 | Aberrant chromosome morphology in human cells defective for Holliday junction resolution | In somatic cells, Holliday junctions can be formed between sister chromatids during the recombinational repair of DNA breaks or after replication fork demise. A variety of processes act upon Holliday junctions to remove them from DNA, in events that are critical for proper chromosome segregation. In human cells, the BL... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
324139 | Precision dating of the Palaeolithic: chronological mapping of the Middle and Upper Palaeolithic of Eurasia | This proposal addresses the chronology of the Middle to Upper Palaeolithic transition of Eurasia, the period between ~60-30,000 years ago, during which the first modern humans dispersed out of Africa into the Old World and Neanderthals disappeared. This is a crucially important interval for understanding late human evo... | [
"The Study of the Human Past",
"Earth System Science"
] |
W1973050880 | Mining Historical Traffic Data using Back Propagation Neural Network for Accurate Location Estimation | Therefore, in this presented work the neural network based location approximation technique is evaluated. During implementation of neural network based predictive algorithm two key deficiencies are observed first the long training time and quality of training patterns. In order to improve both the issues in neural netw... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
10.1126/science.1245711 | Precise and ultrafast molecular sieving through graphene oxide membranes | Graphene-based materials can have well-defined nanometer pores and can exhibit low frictional water flow inside them, making their properties of interest for filtration and separation. We investigate permeation through micrometer-thick laminates prepared by means of vacuum filtration of graphene oxide suspensions. The ... | [
"Condensed Matter Physics",
"Materials Engineering",
"Physical and Analytical Chemical Sciences"
] |
10.1016/j.biopsycho.2017.07.012 | “Lacking warmth”: Alexithymia trait is related to warm-specific thermal somatosensory processing | Alexithymia is a personality trait involving deficits in emotional processing. The personality construct has been extensively validated, but the underlying neural and physiological systems remain controversial. One theory suggests that low-level somatosensory mechanisms act as somatic markers of emotion, underpinning c... | [
"Neuroscience and Disorders of the Nervous System",
"Physiology in Health, Disease and Ageing"
] |
10.1038/s41587-020-0442-2 | Dissecting cellular crosstalk by sequencing physically interacting cells | Crosstalk between neighboring cells underlies many biological processes, including cell signaling, proliferation and differentiation. Current single-cell genomic technologies profile each cell separately after tissue dissociation, losing information on cell–cell interactions. In the present study, we present an approac... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Immunity, Infection and Immunotherapy",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1109/TPEL.2017.2657644 | An Active Trap Filter For Switching Harmonic Attenuation Of Low Pulse Ratio Inverters | Switching harmonic attenuation has always been challenging for inverters used in high-power conversion applications, where ratio of switching to fundamental frequency is low. Addition of multiple LC -trap filters is no doubt a feasible cost-effective method, which has increasingly been used, but generally susceptible t... | [
"Systems and Communication Engineering",
"Products and Processes Engineering"
] |
637305 | Ocean deoxygenation effects on threatened top predators: new understanding and predictions from novel bio-logging instruments and data | Climate-driven reductions in dissolved oxygen (DO) of the global ocean interior (ocean deoxygenation) is leading to expansion of permanent oxygen minimum zones (OMZ) that comprise about 7% of ocean volume. Impacts on marine animal distributions and abundance may be particularly significant for high-oxygen-demand top pr... | [
"Earth System Science",
"Environmental Biology, Ecology and Evolution",
"Physiology in Health, Disease and Ageing"
] |
10.1038/cr.2017.116 | A vital sugar code for ricin toxicity | Ricin is one of the most feared bioweapons in the world due to its extreme toxicity and easy access. Since no antidote exists, it is of paramount importance to identify the pathways underlying ricin toxicity. Here, we demonstrate that the Golgi GDP-fucose transporter Slc35c1 and fucosyltransferase Fut9 are key regulato... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Cell Biology, Development, Stem Cells and Regeneration",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1080/17550874.2012.762812 | On The Delineation Of Tropical Vegetation Types With An Emphasis On Forest Savanna Transitions | Background: There is no generally agreed classification scheme for the many different vegetation formation types occurring in the tropics. This hinders cross-continental comparisons and causes confusion as words such as ‘forest’ and ‘savanna’ have different meanings to different people. Tropical vegetation formations a... | [
"Earth System Science",
"Environmental Biology, Ecology and Evolution"
] |
W1973831471 | The RADICAL framework for implementing and monitoring healthcare risk management | Purpose – The purpose of this paper is to facilitate an integrative approach to the implementation, monitoring and reporting of risk management in healthcare settings.Design/methodology/approach – A framework, identified by the acronym RADICAL, is presented. The underlying principles and the strengths of the framework ... | [
"Prevention, Diagnosis and Treatment of Human Diseases",
"Individuals, Markets and Organisations"
] |
10.1093/sleep/zsz182 | Dynamic modulation of theta–gamma coupling during rapid eye movement sleep | Abstract
Theta phase modulates gamma amplitude in hippocampal networks during spatial navigation and rapid eye movement (REM) sleep. This cross-frequency coupling has been linked to working memory and spatial memory consolidation; however, its spatial and temporal dynamics remains unclear. Here, we first investigate th... | [
"Neuroscience and Disorders of the Nervous System",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1016/j.smim.2013.10.019 | Negative regulatory receptors of the IL-1 family | The IL-1 family of ligands and receptors has a central role in both innate and adaptive immune responses and is tightly controlled by antagonists, decoy receptors, scavengers, dominant negative molecules, miRNAs and other mechanisms, acting extracellularly or intracellularly. During evolution, the development of multip... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1039/C2CP43705H | Exciton Diffusion In Near Infrared Absorbing Solution Processed Organic Thin Films | We report on singlet-singlet annihilation and exciton diffusion in as-prepared p-type and annealed n-type thin films of the low-bandgap quinoidal quaterthiophene [QQT(CN)4] using ultrafast transient absorption measurements. The decay dynamics of exciton populations are well described by a one-dimensional diffusion-limi... | [
"Physical and Analytical Chemical Sciences",
"Condensed Matter Physics",
"Materials Engineering"
] |
681798 | Biomimetic trick to re-balance Osteblast-Osteoclast loop in osteoporoSis treatment: a Topological and materials driven approach | One out of 5 people in their fifties will experience a bone fracture due to osteoporosis (OP)-induced fragility in their lifetime. The OP socio-economic burden is dramatic and involves tens of millions of people in the EU, with a steadily increasing number due to population ageing. Current treatments entail drug-therap... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Physiology in Health, Disease and Ageing",
"Materials Engineering"
] |
10.1016/j.celrep.2015.10.057 | Evolving Models of Pavlovian Conditioning: Cerebellar Cortical Dynamics in Awake Behaving Mice | Three decades of electrophysiological research on cerebellar cortical activity underlying Pavlovian conditioning have expanded our understanding of motor learning in the brain. Purkinje cell simple spike suppression is considered to be crucial in the expression of conditional blink responses (CRs). However, trial-by-tr... | [
"Neuroscience and Disorders of the Nervous System",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1016/j.tim.2018.12.011 | The Road Not Taken: The Rumen Microbiome, Functional Groups, and Community States | The rumen ecosystem represents a classic example of host–microbiome symbiosis. In this obligatory relationship, the host feeds on plant fibers that can only be degraded through a set of complex metabolic cascades, exclusively encoded in rumen-associated microbes. These various metabolic pathways are distributed across ... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Environmental Biology, Ecology and Evolution",
"Integrative Biology: from Genes and Genomes to Systems"
] |
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