id
stringlengths
6
42
title
stringlengths
3
499
abstract
stringlengths
0
6.24k
label
listlengths
0
6
10.1098/rspa.2015.0054
A study of snake-like locomotion through the analysis of a flexible robot model
We examine the problem of snake-like locomotion by studying a system consisting of a planar inextensible elastic rod with adjustable spontaneous curvature, which provides an internal actuation mechanism that mimics muscular action in a snake. Using a Cosserat model, we derive the equations of motion in two special case...
[ "Mathematics", "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1016/j.cell.2018.08.047
Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT
Probiotics are widely prescribed for prevention of antibiotics-associated dysbiosis and related adverse effects. However, probiotic impact on post-antibiotic reconstitution of the gut mucosal host-microbiome niche remains elusive. We invasively examined the effects of multi-strain probiotics or autologous fecal microbi...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Immunity, Infection and Immunotherapy" ]
10.1056/NEJMoa1405386
Inactivating mutations in NPC1L1 and protection from coronary heart disease
Background: Ezetimibe lowers plasma levels of low-density lipoprotein (LDL) cholesterol by inhibiting the activity of the Niemann-Pick C1-like 1 (NPC1L1) protein. However, whether such inhibition reduces the risk of coronary heart disease is not known. Human mutations that inactivate a gene encoding a drug target can m...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1007/978-3-319-46493-0_29
Fast Optical Flow Using Dense Inverse Search
Most recent works in optical flow extraction focus on the accuracy and neglect the time complexity. However, in real-life visual applications, such as tracking, activity detection and recognition, the time complexity is critical. We propose a solution with very low time complexity and competitive accuracy for the compu...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
218222
Modeling the european power sector evolution: low-carbon generation technologies (renewables, ccs, nuclear), the electric infrastructure and their role in the eu leadership in climate policy
The reduction of greenhouse gas emissions is a vital target for the coming decades. From a technology perspective, power generation is the largest responsible for CO2 emissions, therefore great mitigation efforts will be required in this area. From a policy perspective, it is common opinion that the European Union is a...
[ "Earth System Science", "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1016/j.molcel.2018.02.024
ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability
Deubiquitylating enzymes (DUBs) enhance the dynamics of the versatile ubiquitin (Ub) code by reversing and regulating cellular ubiquitylation processes at multiple levels. Here we discovered that the uncharacterized human protein ZUFSP (zinc finger with UFM1-specific peptidase domain protein/C6orf113/ZUP1), which has b...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1109/CPE.2019.8862380
Coordination Of Dual Functional Dynamic Voltage Restorer And Recloser In Power Distribution System
In this paper, the coordination of a dual-functional dynamic voltage restorer (DFDVR) with recloser in power distribution system is proposed. Compared to the conventional dynamic voltage restorer (DVR), the DFDVR can not only compensate the grid voltage distortion to protect the sensitive loads but also limit the fault...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1016/j.cell.2019.07.007
A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production
PIWI-interacting RNAs (piRNAs) guide transposon silencing in animals. The 22–30 nt piRNAs are processed in the cytoplasm from long non-coding RNAs that often lack RNA processing hallmarks of export-competent transcripts. By studying how these transcripts achieve nuclear export, we uncover an RNA export pathway specific...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
W2238642959
Genetic Resources of Energy Crops: Biological Systems to Combat Climate Change
Bioenergy crop plants that function as solar energy collectors and thermo-chemical energy storage systems are the basis for biological systems that are expected to contribute to renewable energy production, help stabilize the rising levels of green house gases (GHG), and mitigate the risk of global climate change (GCC)...
[ "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering", "Earth System Science" ]
10.1101/637975
Prefrontal Attentional Saccades Explore Space Rhythmically
Recent behavioral studies suggest that attention samples space rhythmically. Oscillations in brain activity have been described as a possible mechanism supporting attentional processes. However, the precise mechanism through which this rhythmic exploration of space is subserved by the prefrontal cortical regions at the...
[ "Neuroscience and Disorders of the Nervous System", "Computer Science and Informatics" ]
217506
Novel imaging of the heart for new structural and metabolic diagnosis
Each year cardiovascular disease (CVD) causes over 4 million deaths in Europe. Predictions suggest that 80% of premature heart disease and stroke is preventable, but ~20% of CVDs are misdiagnosed, and in elderly patients up to 60% of CVDs remain undiagnosed. We need to develop new technologies and strategies for early ...
[ "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases", "Systems and Communication Engineering" ]
10.1073/pnas.1910859116
Plasticity in exocytosis revealed through the effects of repetitive stimuli affect the content of nanometer vesicles and the fraction of transmitter released
Electrochemical techniques with disk and nano-tip electrodes, together with calcium imaging, were used to examine the effect of short-interval repetitive stimuli on both exocytosis and vesicular content in a model cell line. We show that the number of events decreases markedly with repeated stimuli suggesting a depleti...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
FR 8800594 W
PROCESS FOR CONTINUOUS DYEING OF A TEXTILE FILAMENT, AND INSTALLATION FOR IMPLEMENTING THE PROCESS
The aim of the invention is to perfect a process for continuous dyeing of a textile filament by impregnation under pressure, followed by pneumatic drying. The dye solution is applied to the filament (1) in an impregnation enclosure (4). The filament then passes into a pneumatic drying enclosure (5) in which the liquid ...
[ "Products and Processes Engineering", "Physical and Analytical Chemical Sciences" ]
851966
Endosomal control of local protein synthesis in axons
Neurons are morphologically complex cells that rely on highly compartmentalized signaling to coordinate cellular functions. The endocytic pathway is a crucial trafficking route by which neurons integrate, spatially process and transfer information. Endosomal trafficking in axons and dendrites ensures that required mole...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1016/j.freeradbiomed.2017.02.013
How widespread is stable protein S-nitrosylation as an end-effector of protein regulation?
Over the last 25 years protein S-nitrosylation, also known more correctly as S-nitrosation, has been progressively implicated in virtually every nitric oxide-regulated process within the cardiovascular system. The current, widely-held paradigm is that S-nitrosylation plays an equivalent role as phosphorylation, providi...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
10.1515/crelle-2018-0026
On the equidistribution of some Hodge loci
We prove the equidistribution of the Hodge locus for certain non-isotrivial, polarized variations of Hodge structure of weight 2 with {h^{2,0}=1} over complex, quasi-projective curves. Given some norm condition, we also give an asymptotic on the growth of the Hodge locus. In particular, this implies the equidistributio...
[ "Mathematics" ]
W1560230211
Reforming metaphorical theology?:a critical assessment of the works of Sallie McFague in the light of her respondents
McFague’s contributions to theology span over 40 years. Does her theological project, which aims to reform the Christian tradition, retain the coherence and consistency needed to fulfil this aim today? Surprisingly, McFague's body of work remains coherent, consistent and viable after many years of debate in relatio...
[ "Texts and Concepts" ]
184429
Passive tracking of people and things for physical behavior analysis
The main goal of passive tracking of people and things (PATH) is to define a new paradigm for physical behavior inference, where the dynamics of physical entities are tracked with minimal implementation cost, maximal privacy preservation, and intrinsically protected secrecy. PATH relies on the detection, tracking, and ...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
W2170394275
Extremely large-scale simulation of a Kardar-Parisi-Zhang model using graphics cards
The octahedron model introduced recently has been implemented onto graphics cards, which permits extremely large scale simulations via binary lattice gases and bit coded algorithms. We confirm scaling behaviour belonging to the 2d Kardar-Parisi-Zhang universality class and find a surface growth exponent: beta=0.2415(15...
[ "Condensed Matter Physics", "Computer Science and Informatics" ]
10.1038/nature18295
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
The interaction of myosin with actin filaments is the central feature of muscle contraction1 and cargo movement along actin filaments of the cytoskeleton2. The energy for these movements is generated during a complex mechanochemical reaction cycle3, 4. Crystal structures of myosin in different states have provided impo...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1039/c7ta05824a
Thermodynamics of paired charge-compensating doped ceria with superior redox performance for solar thermochemical splitting of H<inf>2</inf>O and CO<inf>2</inf>
Paired charge-compensating doped ceria (PCCD) using trivalent and pentavalent cations are evaluated as redox materials for the thermochemical splitting of H2O and CO2. The oxygen nonstoichiometries of PCCD materials with formulas of Ce0. 9A0. 05Nb0. 05O2 (A = Y, La, Sc) and CexLa(1-x)/2Nb(1-x)/2O2 (x = 0. 75, 0. 95) we...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Materials Engineering" ]
10.1101/2020.04.17.029876
Molecular Rationale For Hantavirus Neutralization By A Reservoir Host Derived Monoclonal Antibody
The intricate lattice of Gn and Gc glycoprotein spike complexes at the surface of hantaviruses facilitates host-cell entry and is the primary target of the neutralizing antibody-mediated immune response. Here, through study of a neutralizing monoclonal antibody (mAb 4G2) generated in a bank vole reservoir host followin...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
269051
Molecular Nanotechnology for Life Science Applications: QUantitative Interactomics for Diagnostics, PROteomics and QUantitative Oncology
The main goal of this proposal is to introduce innovative devices and protocols (based on nano- manipulation, the response of micro-(nano-)mechanical oscillators and nano-fluidics) to carry out, precise, high throughput, high sensitivity, and low cost interactomic measurements. We aim at measuring, in parallel, the con...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
W4383114169
HYDROLOGY OF THE RIO DOCE HYDROGRAPHIC BASIN IN THE STATE OF ESPÍRITO SANTO, BRAZIL / HIDROLOGIA DA BACIA HIDROGRÁFICA DO RIO DOCE NO ESTADO DO ESPÍRITO SANTO, BRASIL
O presente estudo da hidrologia da bacia hidrográfica do Rio Doce no estado do Espírito Santo contou com o tratamento estatístico da série histórica (1968 a 2021) de dados da HIDROWEB v3.2.6 da Agência Nacional de Águas, além de dados de radar da SRTM. As vazões acompanham a variação dos dados de precipitação média men...
[ "Earth System Science" ]
10.1038/s41588-019-0399-6
Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids
Chromosome segregation errors cause aneuploidy and genomic heterogeneity, which are hallmarks of cancer in humans. A persistent high frequency of these errors (chromosomal instability (CIN)) is predicted to profoundly impact tumor evolution and therapy response. It is unknown, however, how prevalent CIN is in human tum...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems", "Physiology in Health, Disease and Ageing" ]
10.1038/ncomms12338
CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism
The site-specific insertion of heterologous genetic material into genomes provides a powerful means to study gene function. Here we describe a modular system entitled CRISPaint (CRISPR-assisted insertion tagging) that allows precise and efficient integration of large heterologous DNA cassettes into eukaryotic genomes. ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1016/j.neuroimage.2016.11.022
Faith and oscillations recovered: On analyzing EEG/MEG signals during tACS
Despite recent success in analyzing brain oscillations recorded during transcranial alternating current stimulation (tACS), the field still requires further research to establish standards in artifact removal methods. This includes taking a step back from the removal of the tACS artifact and thoroughly characterizing t...
[ "Neuroscience and Disorders of the Nervous System", "Systems and Communication Engineering" ]
10.3389/fpsyg.2014.01124
What the eyes say about planning of focused referents during sentence formulation: A cross-linguistic investigation
This study investigated how sentence formulation is influenced by a preceding discourse context. In two eye-tracking experiments, participants described pictures of two-character transitive events in Dutch (Experiment 1) and Chinese (Experiment 2). Focus was manipulated by presenting questions before each picture. In t...
[ "The Human Mind and Its Complexity" ]
819424
Flow and Deformation of Cancer tumours near Yielding
The aim of this proposal is to understand when, how and why metastatic tumour cells detach from a tumour. Often, primary tumours do not kill patients, but secondary tumours do. These so-called metastatic tumour cells disassociate from a primary tumour and, ultimately, prove fatal. Currently, we do not understand the ...
[ "Condensed Matter Physics", "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing" ]
10.5194/bg-9-5407-2012
The carbon balance of South America: a review of the status, decadal trends and main determinants
Abstract. We summarise the contemporary carbon budget of South America and relate it to its dominant controls: population and economic growth, changes in land use practices and a changing atmospheric environment and climate. Component flux estimate methods we consider sufficiently reliable for this purpose encompass fo...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
10.1016/j.laa.2019.09.008
Dimensionally sharp inequalities for the linear entropy
We derive an inequality for the linear entropy, that gives sharp bounds for all finite dimensional systems. The derivation is based on generalised Bloch decompositions and provides a strict improvement for the possible distribution of purities for all finite dimensional quantum states. It thus extends the widely used c...
[ "Mathematics", "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1364/OE.23.024923
Distributed Phase Birefringence Measurements Based On Polarization Correlation In Phase Sensitive Optical Time Domain Reflectometers
In this paper a technique to measure the distributed birefringence profile along optical fibers is proposed and experimentally validated. The method is based on the spectral correlation between two sets of orthogonally-polarized measurements acquired using a phase-sensitive optical time-domain reflectometer (ϕOTDR). Th...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1037/xhp0000646
Seeing social events: The visual specialization for dyadic human-human interactions
Detection and recognition of social interactions unfolding in the surroundings is as vital as detection and recognition of faces, bodies, and animate entities in general. We have demonstrated that the visual system is particularly sensitive to a configuration with two bodies facing each other as if interacting. In four...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.3982/ECTA14429
A Note On Comparative Ambiguity Aversion And Justifiability
We consider a decision maker who ranks actions according to the smooth ambiguity criterion of Klibanoff, Marinacci, and Mukerji (2005). An action is justifiable if it is a best reply to some belief over probabilistic models. We show that higher ambiguity aversion expands the set of justifiable actions. A similar result...
[ "Mathematics", "Individuals, Markets and Organisations" ]
232835
Can immune system rejuvenation restore age-related memory loss?
With increased life expectancy, there has been a critical growth in the portion of the population that suffers from age-related cognitive decline and dementia. Attempts are therefore being made to find ways to slow brain-aging processes; successful therapies would have a significant impact on the quality of life of ind...
[ "Immunity, Infection and Immunotherapy", "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
W1485934843
Multitraits evaluation of Pakistani ecotypes of berseem clover (Trifolium alexandrinum L.) under full-irrigation and water restriction conditions
Summary Berseem clover ( Trifolium alexandrinum L.) is an important forage crop in Pakistan and many ecotypes are grown across the country. Its yield is however frequently affected by insufficient irrigation due to unavailability of water. In the present study, twenty Pakistani ecotypes of berseem clover have been eval...
[ "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering", "Products and Processes Engineering" ]
10.1007/978-3-319-33461-5_19
Constant Factor Approximation For Atsp With Two Edge Weights
We give a constant factor approximation algorithm for the Asymmetric Traveling Salesman Problem on shortest path metrics of directed graphs with two different edge weights. For the case of unit edge weights, the first constant factor approximation was given recently by Svensson. This was accomplished by introducing an ...
[ "Mathematics", "Computer Science and Informatics" ]
219092
Chromosome number variations in vivo: probing mechanisms of genesis and elimination
How variations in whole chromosome number impact organism homeostasis remains an open question. Variations to the normal euploid genome content are frequently found in healthy animals and are thought to contribute with phenotypic variability in adverse situations. Yet they are also at the basis of several human disease...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems", "Physiology in Health, Disease and Ageing" ]
10.1109/CDC.2014.7040177
Linear Convergence Rate For Distributed Optimization With The Alternating Direction Method Of Multipliers
Consider the problem of distributed optimization where a network of N agents cooperate to solve a minimization problem of the form inf x equation where function f n is convex and known only by agent n. The Alternating Direction Method of Multipliers (ADMM) has shown to be particularly efficient to solve this kind of p...
[ "Mathematics", "Computer Science and Informatics" ]
interreg_589
Creating a cross-border club for the promotion of products of artisanal fisheries
The project aims at promoting the socio-economic development and regional integration of the territories through the development, qualification and integration of the supply chain of small-scale fisheries with the tourism sector in Sicily and in Tunisia, through the creation of a club of certified fishery products - Th...
[ "Individuals, Markets and Organisations", "Human Mobility, Environment, and Space" ]
GB 3103726 A
Cloth measuring machines
272,392. Vanderveld, A. Dec. 7, 1926. Measuring.-A cloth measuring machine is provided with means, e.g. a metal plate 90, for covering the readings should the measuring operation be started with the cloth beyond its proper starting point and also with a bar 93 which prevents any attempt to introduce cloth between the m...
[ "Products and Processes Engineering" ]
10.2136/vzj2017.04.0083
Rhizosphere-scale quantification of hydraulic and mechanical properties of soil impacted by root and seed exudates
Using rhizosphere-scale physical measurements, we tested the hypothesis that plant exudates gel together soil particles and, on drying, enhance soil water repellency. Barley (Hordeum vulgare L. cv. Optic) and maize (Zea mays L. cv. Freya) root exudates were compared with chia (Salvia hispanica L. ) seed exudate, a co...
[ "Earth System Science", "Physical and Analytical Chemical Sciences", "Environmental Biology, Ecology and Evolution" ]
10.1109/TCOMM.2015.2458857
Iterative Quantum Assisted Multi User Detection For Multi Carrier Interleave Division Multiple Access Systems
With the proliferation of smart-phones and tablet PCs, the data rates of wireless communications have been soaring. Hence, the need for power-efficient communications relying on low-complexity multiple-stream detectors has become more pressing than ever. As a remedy, in this paper we design low-complexity soft-input so...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1038/s41467-019-11703-x
Vapor-deposited zeolitic imidazolate frameworks as gap-filling ultra-low-k dielectrics
The performance of modern chips is strongly related to the multi-layer interconnect structure that interfaces the semiconductor layer with the outside world. The resulting demand to continuously reduce the k-value of the dielectric in these interconnects creates multiple integration challenges and encourages the search...
[ "Condensed Matter Physics", "Systems and Communication Engineering", "Materials Engineering" ]
10.1017/jfm.2013.533
Phase trapping and slipping in a forced hydrodynamically self-excited jet
In a recent study on a coupled laser system, Thévenin et al. (Phys. Rev. Lett. , vol. 107, 2011, 104101) reported the first experimental evidence of phase trapping, a partially synchronous state characterized by frequency locking without phase locking. To determine whether this state can arise in a hydrodynamic system,...
[ "Condensed Matter Physics", "Products and Processes Engineering", "Mathematics" ]
10.1117/12.2272993
Optimal Secure Quantum Teleportation Of Coherent States Of Light
We investigate quantum teleportation of ensembles of coherent states of light with a Gaussian distributed displacement in phase space. Recently, the following general question has been addressed in [P. Liuzzo-Scorpo et al. , arXiv:1705. 03017]: Given a limited amount of entanglement and mean energy available as resour...
[ "Fundamental Constituents of Matter", "Computer Science and Informatics" ]
W1141582719
Young, James and Itihari Toure, Eds.: Asa: Honoring His Life and Work
Young, James and Itihari Toure, eds. Asa: Honoring His Life and Work. Chicago, IL: African American Images, 2013. ISBN: 978-1934-155-844, pbk, bib, pp.154. [ILLUSTRATION OMITTED] A collection of essays by Itihari Toure (Clark Atlanta University; The Jenga Collective), Chike Akua (Georgia State University), Mark A. Loma...
[ "Texts and Concepts", "The Study of the Human Past", "The Social World and Its Interactions" ]
W2096383424
Analyzing different aspects of social network usages on students behaviors and academic performance
The role of social networks has become increasingly relevant in recent years. This research focuses on analyzing the affect of social networks (SN) websites usage on students' behaviors and academic performances. This investigation included students gender based usage patterns of social networks websites with respect t...
[ "The Social World and Its Interactions", "Computer Science and Informatics" ]
10.1038/s41893-019-0223-4
An analytical framework for spatially targeted management of natural capital
A major sustainability challenge is determining where to target management to enhance natural capital and the ecosystem services it provides. Achieving this understanding is difficult, given that the effects of most actions vary according to wider environmental conditions; and this context dependency is typically poorl...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
1261140
Women’S labour activism in eastern europe and transnationally, from the age of empires to the late 20th century
ZARAH explores the history of women’s labour activism and organizing to improve labour conditions and life circumstances of lower and working class women and their communities—moving these women from the margins of labour, gender, and European history to the centre of historical study. ZARAH’s research rationale is ro...
[ "The Study of the Human Past", "The Social World and Its Interactions" ]
W2107455791
Price Stability and Central Bank Independence: Discipline, Credibility, and Democratic Institutions
Abstract Despite mixed empirical evidence, in the past two decades central bank independence (CBI) has been on the rise under the assumption that it ensures price stability. Using an encompassing theoretical approach and new yearly data for de jure CBI (seventy-eight countries, 1973–2008), we reexamine this relationshi...
[ "Institutions, Governance and Legal Systems", "Individuals, Markets and Organisations" ]
W1878277754
Where in the world is it cheapest to cut carbon emissions?*
Countries with low marginal costs of abating carbon emissions may have high total costs, and vice versa, for a given climate mitigation policy. This may help to explain different countries’ policy stances on climate mitigation. We hypothesize that, under a common percentage cut in emissions intensity relative to busine...
[ "Earth System Science", "Individuals, Markets and Organisations" ]
10.1002/anie.201814452
Catalyst-Free Deaminative Functionalizations of Primary Amines by Photoinduced Single-Electron Transfer
The use of pyridinium-activated primary amines as photoactive functional groups for deaminative generation of alkyl radicals under catalyst-free conditions is described. By taking advantage of the visible light absorptivity of electron donor–acceptor complexes between Katritzky pyridinium salts and either Hantzsch este...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1038/nature23009
Nutrient sensing modulates malaria parasite virulence
The lifestyle of intracellular pathogens, such as malaria parasites, is intimately connected to that of their host, primarily for nutrient supply. Nutrients act not only as primary sources of energy but also as regulators of gene expression, metabolism and growth, through various signalling networks that enable cells t...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
GB 9218121 A
Mounting frame and coupling arrangement
A mounting frame, for example a UPVC door or window panel, has its hollow frame members secured together at the corners by a coupling member 205. The coupling member has legs, which carry resilient fingers which are pushed into the cavities of the respective frame members and the fingers sprag against the inside walls,...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1103/PhysRevB.90.041402
Effect of point defects on the optical and transport properties of MoS2 and WS2
Imperfections in the crystal structure, such as point defects, can strongly modify the optical and transport properties of materials. Here, we study the effect of point defects on the optical and dc conductivities of single layers of semiconducting transition metal dichalcogenides with the form MS2, where M=Mo or W. T...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
10.1007/978-3-030-56880-1_26
Reverse Firewalls For Actively Secure Mpcs
Reverse firewalls were introduced at Eurocrypt 2015 by Miro-nov and Stephens-Davidowitz, as a method for protecting cryptographic protocols against attacks on the devices of the honest parties. In a nutshell: a reverse firewall is placed outside of a device and its goal is to “sanitize” the messages sent by it, in such...
[ "Computer Science and Informatics" ]
10.1177/0019464617745926
Back From Shingly Revisiting The Premodern History Of Jews In Kerala
Jewish history in Kerala is based on sources mainly from the colonial period onward and mostly in European languages, failing to account for the premodern history of Jews in Kerala. These early mod. . .
[ "The Study of the Human Past", "Studies of Cultures and Arts" ]
10.1145/2322156.2322158
Janus2 An Fpga Based Supercomputer For Spin Glass Simulations
We describe the past and future of the Janus project. The collaboration started in 2006 and deployed in early 2008 the Janus supercomputer, a facility that allowed to speed-up Monte Carlo Simulations of a class of model glassy systems and provided unprecedented results for some paradigms in Statistical Mechanics. The J...
[ "Condensed Matter Physics", "Computer Science and Informatics" ]
10.1088/1748-9326/10/4/044012
Introduction Of A Simple Model Based Land Surface Dataset For Europe
Land surface hydrology can play a crucial role during extreme events such as droughts, floods and even heat waves. We introduce in this study a new hydrological dataset for Europe that consists of soil moisture, runoff and evapotranspiration (ET). It is derived with a simple water balance model (SWBM) forced with preci...
[ "Earth System Science", "Products and Processes Engineering" ]
10.1007/s10514-017-9683-4
Gaussian process for 6-DoF rigid motions
Data-driven modeling approaches receive significant attention in robotics as they are capable of representing system behavior to which first-order principles cannot be employed. Modeling of human motions, based on observations is one of the many application areas. So far, however, the available probabilistic approaches...
[ "Computer Science and Informatics", "Mathematics" ]
W1699935857
Risk Management of Cyclically Recurring Project Activities of Product Realisation
An extended risk-analysis procedure for new product/service realisation projects is presented in this paper. The usual risk analysis of project activities is based on evaluation of the probability that risk events occur and on evaluation of their consequences. Product/process realisation projects are cyclically recurri...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1016/j.celrep.2018.09.009
Maintenance of Proteostasis by P Body-Mediated Regulation of eIF4E Availability during Aging in Caenorhabditis elegans
Aging is accompanied by a pervasive collapse of proteostasis, while reducing general protein synthesis promotes longevity across taxa. Here, we show that the eIF4E isoform IFE-2 is increasingly sequestered in mRNA processing (P) bodies during aging and upon stress in Caenorhabditis elegans. Loss of the enhancer of mRNA...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
W2055696016
Evaluation of Oyster Mushroom (<i>Pleurotus Ostreatus</i>) as a Biological Growth Promoter on Performance, Humoral Immunity, and Blood Characteristics of Broiler Chicks
This study was conducted to determine the impacts of two levels of oyster mushroom (Pleurotus ostreatus) powder on productive and carcass traits, humoral immune responses, and blood characteristics of Ross 308 male broiler chicks reared to 42 d of age in comparison with a prebiotic supplement. Two hundred and forty, da...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Immunity, Infection and Immunotherapy", "Biotechnology and Biosystems Engineering" ]
10.1111/1758-2229.12363
Metagenomic Evidence For The Presence Of Phototrophic Gemmatimonadetes Bacteria In Diverse Environments
Gemmatimonadetes represents a poorly understood bacterial phylum with only a handful of cultured species. Recently, one of its few representatives, Gemmatimonas phototrophica, was found to contain purple bacterial photosynthetic reaction centres. However, almost nothing is known about the environmental distribution of ...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
787340
Dynamic mechanisms and functional roles of synaptic plasticity in memory
Activity-dependent plasticity of synaptic transmission together with refinement of neural circuits connectivity are amongst the core mechanisms underlying learning and memory. While there is already extensive knowledge on some of the mechanisms of synaptic plasticity, fundamental questions remain on the dynamics of the...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
W2064487881
Numerical Investigation on Roll-Wave Properties: Wave–Wave Interactions, Generality, and Spectrum
AbstractModeling natural roll waves in unstable open channel flows where Froude number F>2 has not been well understood. In this investigation, some evolution properties of natural roll waves are numerically disclosed, with the intention to advance the development of modeling unstable open channel flows. To simulate na...
[ "Mathematics", "Products and Processes Engineering" ]
W1500831085
Data Cube Computational Model with Hadoop MapReduce
XML has become a widely used and well structured data format for digital document handling and message transmission. To find useful knowledge in XML data, data warehouse and OLAP applications aimed at providing supports for decision making should be developed. Apache Hadoop is an open source cloud computing framework t...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
W2003007896
Oxidation of ethylbenzene using some recyclable cobalt nanocatalysts: The role of linker and electrochemical study
Co(II)–Schiff base complexes covalently linked on the organo-functionalized SiO 2 –Al 2 O 3 mixed-oxides. The catalytic activities of the heterogenized cobalt nanocatalysts in the oxidation of ethylbenzene were studied without the need of any solvent . In addition, the electrochemical data about oxidation of cobalt nan...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
10.1111/j.1365-2656.2011.01934.x
Density dependence in group dynamics of a highly social mongoose, Suricata suricatta
1. For social species, the link between individual behaviour and population dynamics is mediated by group-level demography. 2. Populations of obligate cooperative breeders are structured into social groups, which may be subject to inverse density dependence (Allee effects) that result from a dependence on conspecific h...
[ "Environmental Biology, Ecology and Evolution" ]
10.1109/IEDM.2017.8268503
Mos 2 Vo 2 Vdw Heterojunction Devices Tunable Rectifiers Photodiodes And Field Effect Transistors
In this work we report a new class of ultra-thin film devices based on n-n van der Waals (vdW) heteroj unctions of MoS 2 and VO 2 , which show remarkable tunable characteristics. The favorable band alignment combined with the sharp and clean vdW interface determines a tunable diode-like characteristic with a rectificat...
[ "Condensed Matter Physics", "Materials Engineering", "Systems and Communication Engineering" ]
10.1088/1742-6596/283/1/012013
Magneto Elastic Torsional Oscillations Of Magnetars
We extend a general-relativistic ideal magneto-hydrodynamical code to include the effects of elasticity. Using this numerical tool we analyse the magneto-elastic oscillations of highly magnetised neutron stars (magnetars). In simulations without magnetic field we are able to recover the purely crustal shear oscillation...
[ "Universe Sciences", "Fundamental Constituents of Matter" ]
637734
Trace amine-associated receptor 1 (taar1) agonists in a chemogenetic/molecular imaging model of increased dopamine synthesis capacity (ki)
My research plan aims at generating an innovative chemogenetic/positron emission tomography (PET) imaging translational model of striatal dopamine (DA) over-reactivity, the most well-established pathophysiological mechanism underlying schizophrenia. I will use this platform to test the therapeutic efficacy of antipsych...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1016/j.cplett.2012.11.075
Interplay between solvent models and predicted optical spectra: A TD-DFT study of 7-OH-coumarin
Using time-dependent density functional theory, we investigate the solvatochromic effects on the optical spectra of a typical hydroxy coumarin, considering its enol, keto, anionic and cationic forms. The absorption and fluorescence transitions energies have been computed within both the linear-response (LR) and the mor...
[ "Physical and Analytical Chemical Sciences" ]
10.1088/0264-9381/29/20/205002
On A Five Dimensional Version Of The Goldberg Sachs Theorem
Previous work has found a higher dimensional generalization of the ?geodesic part? of the Goldberg?Sachs theorem. We investigate the generalization of the ?shear-free part? of the theorem. A spacetime is defined to be algebraically special if it admits a multiple Weyl aligned null direction (WAND). The algebraically sp...
[ "Mathematics", "Fundamental Constituents of Matter" ]
10.1038/srep18750
Allosteric effects of chromophore interaction with dimeric near-infrared fluorescent proteins engineered from bacterial phytochromes
Fluorescent proteins (FPs) engineered from bacterial phytochromes attract attention as probes for in vivo imaging due to their near-infrared (NIR) spectra and use of available in mammalian cells biliverdin (BV) as chromophore. We studied spectral properties of the iRFP670, iRFP682 and iRFP713 proteins and their mutants...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1126/sciadv.aaw1412
The sequence of events during folding of a DNA origami
We provide a comprehensive reference dataset of the kinetics of a multilayer DNA origami folding. To this end, we measured the folding kinetics of every staple strand and its two terminal segments during constant-temperature assembly of a multilayer DNA origami object. Our data illuminate the processes occurring during...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Synthetic Chemistry and Materials" ]
10.1016/j.mod.2016.11.003
Mechanical forces during muscle development
Muscles are the major force producing tissue in the human body. While certain muscle types specialize in producing maximum forces, others are very enduring. An extreme example is the heart, which continuously beats for the entire life. Despite being specialized, all body muscles share similar contractile mini-machines ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
W2154693868
Prenatal development in rural South Africa: Relationship between birth weight and access to fathers and grandparents
Birth weight is an indicator of prenatal development associated with health in infancy and childhood, and may be affected by the family environment experienced by the mother during pregnancy. Using data from KwaZulu-Natal, South Africa, we explore the importance of the mother's access to the father and grandparents of ...
[ "The Social World and Its Interactions", "Human Mobility, Environment, and Space", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2344661652
Contextualized Planning Using Social Practices
Intelligent agents increasingly need to be aware of the social aspects of their context in order to take the appropriate action. However, existing techniques and platforms only provide partial solutions for this problem which do not take into account the full consequences of the social context. In this paper we propose...
[ "Computer Science and Informatics", "The Social World and Its Interactions" ]
835108
Synthetic biology of non-ribosomal peptide synthetases to generate new peptides
Natural products (NPs) generated by microbial non-ribosomal peptide synthetases (NRPS) represent several very important and valuable clinical antibiotics, immune-suppressive and anti-cancer drugs. NPs have gone on to inspire several synthetic peptides that are used clinically, but contain amino acids (AAs) or other bui...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering" ]
10.1158/0008-5472.CAN-16-0136
Evidence Implicating Immunological Host Effects In The Efficacy Of Metronomic Low Dose Chemotherapy
Conventional chemotherapy drugs administered at a maximum tolerated dose (MTD) remains the backbone for treating most cancers. Low-dose metronomic (LDM) chemotherapy, which utilizes lower, less toxic, doses given on a close regular basis over prolonged periods, is an alternative and better tolerated potential strategy ...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
217948
Levitation with localised tactile and audio feedback for mid-air interactions
This project will be the first to create, prototype and evaluate a radically new human-computer interaction paradigm that empowers the unadorned user to reach into levitating matter, see it, feel it, manipulate it and hear it. Our users can interact with the system in a walk-up-and-use manner without any user instrumen...
[ "Computer Science and Informatics", "Systems and Communication Engineering", "Condensed Matter Physics" ]
10.1002/fld.3710
Numerical approximation of parabolic problems by residual distribution schemes
We are interested in the numerical approximation of steady scalar convection-diffusion problems by means of high order schemes called Residual Distribution schemes. In the inviscid case, one can develop nonlinear Residual Distribution schemes that are nonoscillatory, even in the case of very strong discontinuities, whi...
[ "Mathematics", "Computer Science and Informatics" ]
10.1007/s10494-017-9845-7
Revisiting History Effects in Adverse-Pressure-Gradient Turbulent Boundary Layers
The goal of this study is to present a first step towards establishing criteria aimed at assessing whether a particular adverse-pressure-gradient (APG) turbulent boundary layer (TBL) can be considered well-behaved, i. e. , whether it is independent of the inflow conditions and is exempt of numerical or experimental art...
[ "Products and Processes Engineering", "Condensed Matter Physics" ]
833647
Computable Law
The project addresses the regulation of computations (processes and systems) through an innovative legal & technological framework: it provides epistemic, technical and normative guidance for the de-velopment of computable laws and law compliant computations. The context is the ongoing transformation of the social wor...
[ "Institutions, Governance and Legal Systems", "Computer Science and Informatics" ]
10.1086/682989
The Subaru Coronagraphic Extreme Adaptive Optics System Enabling High Contrast Imaging On Solar System Scales
The Subaru Coronagraphic Extreme Adaptive Optics (SCExAO) instrument is a multipurpose high-contrast imaging platform designed for the discovery and detailed characterization of exoplanetary systems and serves as a testbed for high-contrast imaging technologies for ELTs. It is a multiband instrument which makes use of ...
[ "Physical and Analytical Chemical Sciences", "Universe Sciences" ]
10.1093/pa/gst017
Television in the legislature: The impact of cameras in the house of commons
The introduction of television cameras in legislatures met, in many countries, with serious debate about the potential benefits and costs of broadcasting legislative debate. There were concerns about tendency for cameras to produce less focused, more attention-seeking behaviour amongst party members, and especially lea...
[ "Institutions, Governance and Legal Systems", "The Social World and Its Interactions" ]
10.1145/2939370
Dream An Approach To Estimate Per Task Dram Energy In Multicore Systems
Accurate per-task energy estimation in multicore systems would allow performing per-task energy-aware task scheduling and energy-aware billing in data centers, among other applications. Per-task energy estimation is challenged by the interaction between tasks in shared resources, which impacts tasks’ energy consumption...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1016/j.devcel.2012.10.009
Curvature, Lipid Packing, and Electrostatics of Membrane Organelles: Defining Cellular Territories in Determining Specificity
Whereas some rare lipids contribute to the identity of cell organelles, we focus on the abundant lipids that form the matrix of organelle membranes. Observations using bioprobes and peripheral proteins, notably sensors of membrane curvature, support the prediction that the cell contains two broad membrane territories: ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1038/srep07435
Temporal dynamics of the ABC transporter response to insecticide treatment: Insights from the malaria vector Anopheles stephensi
In insects, ABC transporters have been shown to contribute to defence/resistance to insecticides by reducing toxic concentrations in cells/tissues. Despite the extensive studies about this detoxifying mechanism, the temporal patterns of ABC transporter activation have been poorly investigated. Using the malaria vector ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1016/j.molmet.2017.08.007
An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism
Objective Strategies improving skeletal muscle mitochondrial capacity are commonly paralleled by improvements in (metabolic) health. We and others previously identified microRNAs regulating mitochondrial oxidative capacity, but data in skeletal muscle are limited. Therefore, the present study aimed to identify novel mi...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1021/jacs.8b04928
Self-Catalytic Reaction of SO<inf>3</inf> and NH<inf>3</inf> to Produce Sulfamic Acid and Its Implication to Atmospheric Particle Formation
Sulfur trioxide (SO3) is one of the most active chemical species in the atmosphere, and its atmospheric fate has profound implications to air quality and human health. The dominant gas-phase loss pathway for SO3 is generally believed to be the reaction with water molecules, resulting in sulfuric acid. The latter is vie...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
W2137431032
Europe at a Crossroads: Failed Ideas, Fictional Facts, and Fatal Consequences
The crisis of the European Monetary Union has revealed the weakness and the fragility of the European integration process. The paper examines the institutional changes which are at the root of the instability. What are the driving forces behind the introduction of the euro? What role do theoretical considerations play ...
[ "Institutions, Governance and Legal Systems", "Individuals, Markets and Organisations" ]
803277
Levitated Nanoparticles for Technology and Quantum Nanophysics: New frontiers in physics at the nanoscale.
Technology is continuously miniaturizing. As it reaches the nanoscale we face unique challenges, such as managing thermal. From the other direction, advances in the quantum physics of a few atoms, ions, and solid-state qubits mean that we increasingly wish to scale up quantum systems, or interface them with nanoscale d...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter", "Systems and Communication Engineering" ]
W2375568108
Construction for processing map based on DMM and identification for the stable hot-working parameters of Ti-6Al-2Zr-1Mo-1V alloy
Several series of billet samples were compressed on heat physical simulation machine under deformation temperatures 1073-1323K and strain rates 0.01-10s-1,then the true stress-strain data collected resulted the performance of calculations for strain rate sensitivity(m-value),power dissipation efficiency(η-value) and in...
[ "Condensed Matter Physics", "Materials Engineering" ]
W3104371034
Atoms and molecules in intense laser fields: gauge invariance of theory and models
Gauge invariance was discovered in the development of classical electromagnetism and was required when the latter was formulated in terms of the scalar and vector potentials. It is now considered to be a fundamental principle of nature, stating that different forms of these potentials yield the same physical descriptio...
[ "Physical and Analytical Chemical Sciences", "Fundamental Constituents of Matter" ]
758053
A Fiber Optic Transceiver for Superconducting Qubits
Many researchers in basic science and large IT companies are convinced that superconducting quantum processors will soon help solve complex problems faster, improve optimization and simulation, and boost the progress in artificial intelligence. A worldwide quantum web is the next logical step. It would not only improve...
[ "Condensed Matter Physics", "Systems and Communication Engineering", "Materials Engineering" ]
866400
Ordering, Constructing, Empowering: Fragments of the Roman Republican Antiquarians
This project will radically transform our understanding of Roman Republican culture by establishing a new framework for the elaboration of knowledge and the religious and institutional structures of the Roman Republic. We will do so through the first systematic and comprehensive account of a group of Republican writers...
[ "The Study of the Human Past", "Texts and Concepts" ]
173294
From aquileia to singidunum (belgrade), reconstructing the paths of roman travelers
The RecRoad project aims to reconstruct the Roman road going from Aquileia, in the north-east of Italy, to Singidunum, on the Danube river. This was one of the main road axes of the Empire and it connected the Venetian area with the Pannonia Superior and the Danubian limes: the road was longer than 450 miles, passing t...
[ "The Study of the Human Past", "Human Mobility, Environment, and Space", "Computer Science and Informatics" ]