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Bio-agricultural management and control
The European Union identifies as a priority the growth of eco-compatible agriculture in the framework of promoting sustainable development. As regards rural development the CAP (Common Agricultural Policy) focuses on the development of organic agriculture. Regional Plans for Rural Development follow in the same directi...
[ "Environmental Biology, Ecology and Evolution", "Human Mobility, Environment, and Space", "Institutions, Governance and Legal Systems" ]
10.16997/wpcc.313
Do not harm in private chat apps: Ethical issues for research on and with WhatsApp
WhatsApp has remained under the radar for it is scarcely accessible to overt scholarly scrutiny. Encrypted chat apps allow for a certain degree of perceived secrecy. Yet the high frequency of civic engagement makes ethnographic research a time-consuming exercise. This article investigates how digital ethnography inside...
[ "The Social World and Its Interactions", "Computer Science and Informatics" ]
10.1007/JHEP06(2016)134
Drude In D Major
We study holographic momentum relaxation in the limit of a large number of spacetime dimensions D. For an axion model we find that momentum conservation is restored as D becomes large. To compensate we scale the strength of the sources with D so that momentum is relaxed even at infinite D. We analytically obtain the ...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
10.1083/jcb.201006159
Making heads or tails of phospholipids in mitochondria
Mitochondria are dynamic organelles whose functional integrity requires a coordinated supply of proteins and phospholipids. Defined functions of specific phospholipids, like the mitochondrial signature lipid cardiolipin, are emerging in diverse processes, ranging from protein biogenesis and energy production to membran...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
864174
Musical and Poetic Creativity for A Unique Moment in the Western Christian Liturgy, c.1000-1500
BENEDICAMUS pursues a transformative focus on creative practices surrounding a particular moment in the Western Christian liturgy: the exclamation Benedicamus Domino (“Let us Bless the Lord”), which sounded in song several times a day from c.1000 to 1500. This moment was granted special musical licence c.1000: singers ...
[ "The Study of the Human Past", "Texts and Concepts" ]
10.1007/s00221-014-4183-7
The uses and interpretations of the motor-evoked potential for understanding behaviour
The motor-evoked potential (MEP) elicited in peripheral muscles by transcranial magnetic stimulation (TMS) over human motor cortex is one of the hallmark measures for non-invasive quantification of cortical and spinal excitability in cognitive and clinical neuroscience. In the present article, we distinguish three main...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
EP 90402007 A
Device for restricting the oil flow in a rotating shaft.
Dispositif (28) de limitation de débit d'un lubrifiant au travers d'un passage axial (18) d'un arbre (10) en rotation, caractérisé en ce qu'il comprend un organe (36) formant cloison transversale, fixé dans ledit passage axial et présentant une face interne (40) tournée vers le passage (18) et une face externe (38) tou...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1016/j.dsr.2014.10.001
Oxygen distribution and aerobic respiration in the north and south eastern tropical Pacific oxygen minimum zones
Highly sensitive STOX O2 sensors were used for determination of in situ O2 distribution in the eastern tropical north and south Pacific oxygen minimum zones (ETN/SP OMZs), as well as for laboratory determination of O2 uptake rates of water masses at various depths within these OMZs. Oxygen was generally below the detec...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Physical and Analytical Chemical Sciences" ]
10.1088/0953-8984/23/21/215004
The Autocorrelation Function For Island Areas On Self Affine Surfaces
The spatial distribution of regions that lie above contours of constant height through a self-affine surface is studied as a function of the Hurst exponent H. If the surface represents a landscape, these regions correspond to islands. When the surface represents the height difference for contacting surfaces, the regio...
[ "Condensed Matter Physics", "Mathematics" ]
10.1093/neuonc/noy007
The aberrant splicing of BAF45d links splicing regulation and transcription in glioblastoma
Background Glioblastoma, the most aggressive primary brain tumor, is genetically heterogeneous. Alternative splicing (AS) plays a key role in numerous pathologies, including cancer. The objectives of our study were to determine whether aberrant AS could play a role in the malignant phenotype of glioma and to understand...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
10.1287/mnsc.2019.3356
Creating Platforms by Hosting Rivals
We explore conditions under which a multiproduct firm can profitably turn itself into a platform by “hosting rivals,” that is, by inviting rivals to sell products or services on top of its core product. Hosting eliminates the additional shopping costs to consumers of buying a specialist rival’s competing version of the...
[ "Individuals, Markets and Organisations" ]
10.1364/OL.41.001110
40 Ghz Pulse Source Based On Xpm Induced Focusing In Normally Dispersive Optical Fibers
We theoretically and experimentally investigate the design of a high-repetition rate source delivering well-separated picosecond pulses thanks to the nonlinear compression of a dual-frequency beat signal within a cavity-less normally dispersive fiber-based setup. This system is well described by a set of two coupled NL...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
W1983610078
Experiences of the Relatives of Patients Undergoing Cranial Surgery for a Brain Tumor
The functional changes that develop because of neurological sequelae in patients with a brain tumor have a negative effect on daily activities and self-care. This situation in turn has a negative effect on the lives of the patients' relatives and increases their work load. We interviewed 10 relatives of patients who ha...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1088/1475-7516/2019/05/048
Measuring The Homogeneity Of The Universe Using Polarization Drift
We propose a method to probe the homogeneity of a general universe, without assuming symmetry. We show that isotropy can be tested at remote locations on the past lightcone by comparing the line-of-sight and transverse expansion rates, using the time dependence of the polarization of Cosmic Microwave Background photons...
[ "Universe Sciences" ]
10.1364/OE.19.011759
Under Filling Trapping Objectives Optimizes The Use Of The Available Laser Power In Optical Tweezers
For optical tweezers, especially when used in biological studies, optimizing the trapping efficiency reduces photo damage or enables the generation of larger trapping forces. One important, yet not-well understood, tuning parameter is how much the laser beam needs to be expanded before coupling it into the trapping obj...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1016/j.psyneuen.2015.10.017
Stress influences environmental donation behavior in men
Stress has been found to have both positive and negative effects on prosocial behavior, suggesting the involvement of moderating factors such as context and underlying motives. In the present study, we investigated the conditions under which acute stress leads to an increase vs. decrease in environmental donation beha...
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity" ]
10.4204/EPTCS.251.34
Condorcet S Principle And The Preference Reversal Paradox
We prove that every Condorcet-consistent voting rule can be manipulated by a voter who completely reverses their preference ranking, assuming that there are at least 4 alternatives. This corrects an error and improves a result of [Sanver, M. R. and Zwicker, W. S. (2009). One-way monotonicity as a form of strategy-p...
[ "Mathematics", "Individuals, Markets and Organisations" ]
10.3389/fneur.2013.00101
Comparison of functional recovery of manual dexterity after unilateral spinal cord lesion or motor cortex lesion in adult macaque monkeys
In relation to mechanisms involved in functional recovery of manual dexterity from cervical cord injury or from motor cortical injury, our goal was to determine whether the movements that characterize post-lesion functional recovery are comparable to original movement patterns or do monkeys adopt distinct strategies to...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1093/rfs/hhq062
Reward for luck in a dynamic agency model
This article studies a continuous time principal-agent problem of a firm whose cash flows are determined by the manager's unobserved effort. The firm's cash flows are further subject to persistent and publicly observable shocks that are beyond the manager's control. While standard contracting models predict that compen...
[ "Individuals, Markets and Organisations" ]
EP 08253342 A
Motor controller of air conditioner and method of the motor controller
The present invention relates to a motor controller for an air conditioner and a motor control method. The motor controller including a converter converting AC utility power into DC power and an inverter having a plurality of switching elements, the inverter receiving the DC power, converting the received DC power into...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1016/j.neuroscience.2017.04.005
Impact of thalamocortical input on barrel cortex development
The development of cortical maps requires the balanced interaction between genetically determined programs and input/activity-dependent signals generated spontaneously or triggered from the environment. The somatosensory pathway of mice provides an excellent scenario to study cortical map development because of its hig...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.3791/57312
In Vivo Imaging Of Muscle Tendon Morphogenesis In Drosophila Pupae
Muscles together with tendons and the skeleton enable animals including humans to move their body parts. Muscle morphogenesis is highly conserved from animals to humans. Therefore, the powerful Drosophila model system can be used to study concepts of muscle-tendon development that can also be applied to human muscle bi...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1186/s13068-018-1082-3
Efficient whole cell biocatalyst for formate-based hydrogen production
Background: Molecular hydrogen (H2) is an attractive future energy carrier to replace fossil fuels. Biologically and sustainably produced H2 could contribute significantly to the future energy mix. However, biological H2 production methods are faced with multiple barriers including substrate cost, low production rates,...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering" ]
10.1002/eji.201545487
Cross-regulation between cytokine and microRNA pathways in T cells
microRNA (miRNA) mediated regulation of protein expression has emerged as an important mechanism in T-cell physiology, from development and survival to activation, proliferation, and differentiation. One of the major classes of proteins involved in these processes are cytokines, which are both key input signals and maj...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W1942545547
A TRANSLATION ANALYSIS OF IDIOMATIC EXPRESSIONS IN CHOCOLAT BY JOANNE HARRIS AND ITS TRANSLATION BY IBNU SETIAWAN
This study is intended to analyze the translation strategies used by the translator in translating the idiomatic expressions; and the degree of meaning equivalence of the translation of idiomatic expressions in Chocolat by Joanne Harris and into Chocolat by Ibnu Setiawan. This study uses descriptive quantitative and ...
[ "Texts and Concepts" ]
10.1089/ars.2014.6238
NOX4 in Mitochondria: Yeast Two-Hybrid-Based Interaction with Complex i Without Relevance for Basal Reactive Oxygen Species?
NADPH oxidases (NOXs) represent the only known dedicated source of reactive oxygen species (ROS) and thus a prime therapeutic target. Type 4 NOX is unique as it produces H2O2, is constitutively active, and has been suggested to localize to cardiac mitochondria, thus possibly linking mitochondrial and NOX-derived ROS fo...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1186/s12942-019-0179-7
Access to and availability of exercise facilities in Madrid: An equity perspective
Background: Identifying socioeconomic determinants that are associated with access to and availability of exercise facilities is fundamental to supporting physical activity engagement in urban populations, which in turn, may reduce health inequities. This study analysed the relationship between area-level socioeconomic...
[ "Human Mobility, Environment, and Space", "Prevention, Diagnosis and Treatment of Human Diseases", "The Social World and Its Interactions" ]
W154222689
The Offshore Resources Scheduling Problem: Detailing a Constraint Programming Approach
The development of maritime oil wells depends on the availability of specialized fleet capable of performing the required activities. In addition, the exploitation of each well can only start when it is connected through pipes to a producing unit. The Offshore Resources Scheduling Problem (ORSP) combines such restricti...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1038/s41598-017-00132-9
Comparative genomics reveals contraction in olfactory receptor genes in bats
Gene loss and gain during genome evolution are thought to play important roles in adaptive phenotypic diversification. Among mammals, bats possess the smallest genomes and have evolved the unique abilities of powered flight and laryngeal echolocation. To investigate whether gene family evolution has contributed to the ...
[ "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1088/0957-4484/24/9/095201
Electron-induced limitation of surface plasmon propagation in silver nanowires
Plasmonic circuitry is considered as a promising solution-effective technology for miniaturizing and integrating the next generation of optical nano-devices. A key element is the shared metal network between electrical and optical information enabling an efficient hetero-integration of an electronic control layer and a...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
682540
Translational and Transdisciplinary research in Modeling Infectious Diseases
TransMID focuses on the development of novel methods to estimate key epidemiological parameters from both serological and social contact data, with the aim to significantly expand the range of public health questions that can be adequately addressed using such data. Using new statistical and mathematical theory and new...
[ "Mathematics", "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
MX 2021007513 A
QUINT-FOCAL DIFFRACTIVE INTRAOCULAR LENS.
A diffractive quint focal intraocular lens includes a base optic and a diffractive element. The base optic has a base curvature that corresponds to a base power. The diffractive element provides constructive interference in at least five consecutive diffractive orders to create a set of five focal points for vision fro...
[ "Products and Processes Engineering", "Materials Engineering", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1021/acscentsci.9b00800
Carbons with Regular Pore Geometry Yield Fundamental Insights into Supercapacitor Charge Storage
We conduct molecular dynamics simulations of electrical double-layer capacitors (EDLCs) using a library of ordered, porous carbon electrode materials called zeolite templated carbons (ZTCs). The well-defined pore shapes of the ZTCs enable us to determine the influence of pore geometry on both charging dynamics and char...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.7150/thno.23853
Image-guided surgery using near-infrared Turn-ON fluorescent nanoprobes for precise detection of tumor margins
Complete tumor removal during surgery has a great impact on patient survival. To that end, the surgeon should detect the tumor, remove it and validate that there are no residual cancer cells left behind. Residual cells at the incision margin of the tissue removed during surgery are associated with tumor recurrence and ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Synthetic Chemistry and Materials" ]
10.1073/pnas.1413271112
Revealing bacterial targets of growth inhibitors encoded by bacteriophage T7
Today's arsenal of antibiotics is ineffective against some emerging strains of antibiotic-resistant pathogens. Novel inhibitors of bacterial growth therefore need to be found. The target of such bacterialgrowth inhibitors must be identified, and one way to achieve this is by locating mutations that suppress their inhib...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Immunity, Infection and Immunotherapy" ]
10.1016/j.jaci.2010.04.021
The role of viruses in acute exacerbations of asthma
Viral respiratory infections are the most common cause of an acute asthma exacerbation in both children and adults and represent a significant global health burden. An increasing body of evidence supports the hypothesis that these infections cause a greater degree of morbidity in asthmatic subjects than in the healthy ...
[ "Physiology in Health, Disease and Ageing", "Immunity, Infection and Immunotherapy" ]
10.1016/j.neuroimage.2015.05.031
Human aging alters the neural computation and representation of space
The hippocampus and striatum are core neural circuits involved in spatial learning and memory. Although both neural systems support spatial navigation, experimental and theoretical evidence indicate that they play different roles. In particular, whereas hippocampal place cells generate allocentric neural representation...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
TW 112102310 A
Mosquito noise filtering
In one aspect, a method to reduce compression artefacts, includes generating a first set of weights based on pixel value differences, producing a soft binned histogram from values in a neighborhood of pixels, generating an adapted histogram from the soft binned histogram using interpolation, generating occurrence densi...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
851054
Early embryonic events, life-long consequences: DNA methylation dynamics in mammalian development
Immediately after fertilization, mammalian genomes undergo a dramatic reshaping of the epigenome as the embryo transitions from the zygote into the pluripotent cells primed for lineage commitment. This is best exemplified by DNA methylation reprogramming, as the gametic patterns are largely erased, and the embryonic ge...
[ "Integrative Biology: from Genes and Genomes to Systems", "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1038/s41559-017-0193
Phylogenetic rooting using minimal ancestor deviation
Ancestor-descendent relations play a cardinal role in evolutionary theory. Those relations are determined by rooting phylogenetic trees. Existing rooting methods are hampered by evolutionary rate heterogeneity or the unavailability of auxiliary phylogenetic information. Here we present a rooting approach, the minimal a...
[ "Mathematics", "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1016/j.ceb.2017.10.003
Mechanical cell competition
Maintenance of tissue organization is crucial to ensure normal organ function and organism viability. Tissues are loaded with the ability to sense the available space, measuring cell density and adapting their behaviour accordingly. To keep homeostasis, compression pressure generated by local cell density increment tri...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing" ]
10.1242/dev.173328
Molecular signatures identify immature mesenchymal progenitors in early mouse limb buds that respond differentially to morphogen signaling
The key molecular interactions governing vertebrate limb bud development are a paradigm to study the mechanisms controlling progenitor cell proliferation and specification during vertebrate organogenesis. However, little is known about the cellular heterogeneity of the mesenchymal progenitors in early limb buds that ul...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1111/mec.12209
Diversity and evolutionary patterns of bacterial gut associates of corbiculate bees
The animal gut is a habitat for diverse communities of microorganisms (microbiota). Honeybees and bumblebees have recently been shown to harbour a distinct and species poor microbiota, which may confer protection against parasites. Here, we investigate diversity, host specificity and transmission mode of two of the mos...
[ "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
337591
Exoplanets in Transit and their Atmosphere
Since the discoveries of giant planets outside our Solar System, over 800 extra-solar planets have been detected and several thousands candidates are awaiting confirmation. They have revolutionized planetary science, by placing our once unique solar system into context. The subset of extrasolar planets that transit the...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
10.1128/AEM.02927-16
An Effective Counterselection System For Listeria Monocytogenes And Its Use To Characterize The Monocin Genomic Region Of Strain 10403S
Construction of Listeria monocytogenes mutants by allelic exchange has been laborious and time-consuming due to lack of proficient selection markers for the final recombination event, that is, a marker conveying substance sensitivity to the bacteria bearing it, enabling the exclusion of merodiploids and selection for p...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Biotechnology and Biosystems Engineering" ]
637049
Psychiatric ratings using intermediate stratified markers 2
The current nosology of neuropsychiatric disorders provides a pragmatic approach to diagnosis and treatment choice but lacks reference to quantitative biological underpinnings of disease. This weakness impedes innovative drug development. To test whether a quantitative biological approach to the understanding and class...
[ "Neuroscience and Disorders of the Nervous System", "Prevention, Diagnosis and Treatment of Human Diseases", "Integrative Biology: from Genes and Genomes to Systems", "The Human Mind and Its Complexity" ]
10.1111/gbi.12148
Early evolution of large micro-organisms with cytological complexity revealed by microanalyses of 3.4 Ga organic-walled microfossils
The Strelley Pool Formation (SPF) is widely distributed in the East Pilbara Terrane (EPT) of the Pilbara Craton, Western Australia, and represents a Paleoarchean shallow-water to subaerial environment. It was deposited ~3. 4 billion years ago and displays well-documented carbonate stromatolites. Diverse putative microf...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W3103298159
Scalar perturbations of a single-horizon regular black hole
We investigate the massless scalar field perturbations, including the quasinormal mode spectrum and the ringdown waveform, of a regular black hole spacetime that was derived via the Loop Quantum Gravity inspired polymer quantization of spherical $4$D black holes. In contrast to most, if not all, of the other regular bl...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
10.1002/qj.3094
Stochastic representations of model uncertainties at ECMWF: state of the art and future vision
Members in ensemble forecasts differ due to the representations of initial uncertainties and model uncertainties. The inclusion of stochastic schemes to represent model uncertainties has improved the probabilistic skill of the ECMWF ensemble by increasing reliability and reducing the error of the ensemble mean. Recent ...
[ "Earth System Science", "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1002/anie.201906359
A Karplus Equation for the Conformational Analysis of Organic Molecular Crystals
Vicinal scalar couplings (3J) are extensively used for the conformational analysis of organic compounds in the liquid state through empirical Karplus equations. In contrast, there are no examples of such use for the structural investigation of solids. With the support of first principles calculations, we demonstrate he...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1016/j.actbio.2015.12.030
Arrays of 3D double-network hydrogels for the high-throughput discovery of materials with enhanced physical and biological properties
Synthetic hydrogels are attractive biomaterials due to their similarity to natural tissues and their chemical tunability, which can impart abilities to respond to environmental cues, e. g. temperature, pH and light. The mechanical properties of hydrogels can be enhanced by the generation of a double-network. Here, we ...
[ "Materials Engineering", "Synthetic Chemistry and Materials" ]
10.1088/1475-7516/2016/05/061
New Quasidilaton Theory In Partially Constrained Vielbein Formalism
In this work we study the partially constrained vielbein formulation of the new quasidilaton theory of massive gravity, where the quasidilaton field couples to both physical and fiducial metrics simultaneously via a composite effective metric and Lorentz violation is introduced by a constraint on the vielbein. This for...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
10.1098/rspb.2014.1016
Individual-level personality influences social foraging and collective behaviour in wild birds
There is increasing evidence that animal groups can maintain coordinated behaviour and make collective decisions based on simple interaction rules. Effective collective action may be further facilitated by individual variation within groups, particularly through leader-follower polymorphisms. Recent studies have sugges...
[ "Environmental Biology, Ecology and Evolution", "Computer Science and Informatics" ]
10.5194/tc-12-3293-2018
Carbonaceous material export from Siberian permafrost tracked across the Arctic Shelf using Raman spectroscopy
Warming-induced erosion of permafrost from Eastern Siberia mobilises large amounts of organic carbon and delivers it to the East Siberian Arctic Shelf (ESAS). In this study Raman spectroscopy of carbonaceous material (CM) was used to characterise, identify and track the most recalcitrant fraction of the organic load: 1...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
172954
Innovative 5-part haematology analyser for near-patient diagnostics
The INNOHEM project will develop and validate the first Complete Blood cell Count (CBC) haematology analyser including 5-part differential and reticulocytes (5-part analyser) for the decentralized, low-volume testing haematology market. Today, CBC tests are performed using either 3-part or 5-part analysers. The latter ...
[ "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1007/s00220-014-2095-9
On the Ginzburg–Landau Functional in the Surface Superconductivity Regime
We present new estimates on the two-dimensional Ginzburg–Landau energy of a type-II superconductor in an applied magnetic field varying between the second and third critical fields. In this regime, superconductivity is restricted to a thin layer along the boundary of the sample. We provide new energy lower bounds, prov...
[ "Condensed Matter Physics", "Mathematics" ]
W980708197
Economical analysis of saturation mutagenesis experiments
Saturation mutagenesis is a powerful technique for engineering proteins, metabolic pathways and genomes. In spite of its numerous applications, creating high-quality saturation mutagenesis libraries remains a challenge, as various experimental parameters influence in a complex manner the resulting diversity. We explore...
[ "Individuals, Markets and Organisations", "Biotechnology and Biosystems Engineering", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
947978
Spanning Subgraphs in Graphs
Graph Theory is a highly active area of Combinatorics with strong links to fields such as Optimisation and Theoretical Computer Science. A fundamental meta-problem in Graph Theory is the following: given a graph H, what conditions guarantee that another graph G contains a copy of H as a subgraph? This is particularly ...
[ "Mathematics", "Computer Science and Informatics" ]
Q4298401
Community Areas of Sustainable Care And Dementia Excellence in Europe
To develop a financially sustainable approach to elderly/dementia care (EDC) that can be replicated across the 2Seas area & potentially further across Europe. Uniquely this will be tested via existing state owned buildings. The facilities created will provide short term respite & longer term care & will fully engage wi...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing", "Neuroscience and Disorders of the Nervous System" ]
10.1038/s41598-018-38213-y
Malleability of the self: electrophysiological correlates of the enfacement illusion
Self-face representation is fundamentally important for self-identity and self-consciousness. Given its role in preserving identity over time, self-face processing is considered as a robust and stable process. Yet, recent studies indicate that simple psychophysics manipulations may change how we process our own face. S...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1051/0004-6361/201526530
Cut Off Period For Slow Magnetoacoustic Waves In Coronal Plasma Structures
Context. There is abundant observational evidence of longitudinal compressive waves in plasma structures of the solar corona, which are confidently interpreted in terms of slow magnetoacoustic waves. The uses of coronal slow waves in plasma diagnostics, as well as analysis of their possible contribution to coronal heat...
[ "Universe Sciences", "Fundamental Constituents of Matter" ]
W2016221630
Vibration signal analysis system based on hybrid programming of Delphi and Matlab
A vibration signal analysis system introduced by this paper adopts hybrid programming of Matlab and Delphi, using data file for agency to achieve data communication. The procedure of signal analysis system is written and turned into the independent executable file under the environment of Matlab, which is called under ...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1002/evan.21508
Tropical forests and the genus Homo
Tropical forests constitute some of the most diverse and complex terrestrial ecosystems on the planet. From the Miocene onward, they have acted as a backdrop to the ongoing evolution of our closest living relatives, the great apes, and provided the cradle for the emergence of early hominins, who retained arboreal physi...
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]
10.5194/gmd-11-4515-2018
Evaluation of Monte Carlo tools for high-energy atmospheric physics II: relativistic runaway electron avalanches
Abstract. The emerging field of high-energy atmospheric physics studies how high-energy particles are produced in thunderstorms, in the form of terrestrial γ-ray flashes and γ-ray glows (also referred to as thunderstorm ground enhancements). Understanding these phenomena requires appropriate models of the interaction o...
[ "Fundamental Constituents of Matter", "Earth System Science", "Computer Science and Informatics" ]
W2057194677
Indian Ocean maritime security: energy, environmental and climate challenges
For a comprehensive and meaningful understanding, the maritime-related security challenges facing the Indian Ocean littoral states need to be looked at broadly. Non-traditional security issues – from energy security and climate security to transnational terrorism and environmental degradation – are as important as trad...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
W2293925958
Usability of production systems for discharge letters
At the end of an inpatient stay, the hospital physician produces a discharge letter intended for the General Practitioner in order to ensure the continuity of care between hospital and general practice. The French National Health Authority recommends (i) that the discharge letter should reach its addressee within 8 day...
[ "Computer Science and Informatics", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2922120245
The Effect of Autologous Protein Solution on the Inflammatory Cascade in Stimulated Equine Chondrocytes
Cartilage injury occurs commonly in equine athletes, often precipitating posttraumatic osteoarthritis (PTOA). Orthobiologics such as autologous conditioned serum (ACS) and autologous protein solution (APS) may be useful in decreasing posttraumatic inflammation, thereby preventing PTOA. The objective of this study was t...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1140/epjc/s10052-014-3174-y
Squark and gluino production cross sections in TeV
We present state-of-the-art cross section predictions for the production of supersymmetric squarks and gluinos at the upcoming LHC run with a centre-of-mass energy of and TeV, and at potential future colliders operating at and TeV. The results are based on calculations which include the resummation of soft-gluon emissi...
[ "Fundamental Constituents of Matter" ]
221962
The unknown science: understanding the epistemology of logic through practice
We take ourselves to know certain logical claims, for example that no contradictions are true. However, we currently fail to have an adequate account of how we possess logical knowledge. Historical attempts to explain this knowledge, such as appeals to intuition, have been found to be ultimately unsatisfactory, either ...
[ "Mathematics", "Texts and Concepts" ]
10.1016/j.jconrel.2012.04.008
Virus-mediated gene delivery for human gene therapy
After over 20 years from the first application of gene transfer in humans, gene therapy is now a mature discipline, which has progressively overcome several of the hurdles that prevented clinical success in the early stages of application. So far, the vast majority of gene therapy clinical trials have exploited viral v...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Biotechnology and Biosystems Engineering" ]
W1986579256
Tyrosinase as a multifunctional reporter gene for Photoacoustic/MRI/PET triple modality molecular imaging
Development of reporter genes for multimodality molecular imaging is highly important. In contrast to the conventional strategies which have focused on fusing several reporter genes together to serve as multimodal reporters, human tyrosinase (TYR)--the key enzyme in melanin production--was evaluated in this study as a ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Physical and Analytical Chemical Sciences" ]
10.1016/j.cell.2014.07.044
Molecular architecture of the 40S · eIF1 · eIF3 translation initiation complex
Eukaryotic translation initiation requires the recruitment of the large, multiprotein eIF3 complex to the 40S ribosomal subunit. We present X-ray structures of all major components of the minimal, six-subunit Saccharomyces cerevisiae eIF3 core. These structures, together with electron microscopy reconstructions, cross-...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences" ]
175138
Transforming digital in-content advertising to deliver global scale
Today, digital advertising is dominated by big, US-driven companies like Google and Facebook, who provide the majority of the ads we see online. The old dominant concept has been to sell and show static banner ads in a fixed location, separated from Publisher digital content. The problem with this approach is that ads ...
[ "Computer Science and Informatics", "Individuals, Markets and Organisations" ]
10.1137/140972652
Endemic Bubbles Generated By Delayed Behavioral Response Global Stability And Bifurcation Switches In An Sis Model
During infectious disease outbreaks, people may reduce their contact numbers or take other precautions to prevent transmission. The change in their behavior can be directly or indirectly triggered by the density of infected individuals in the population. In this paper, we investigate an SIS (susceptible-infected-suscep...
[ "Mathematics", "Immunity, Infection and Immunotherapy" ]
10.1038/sdata.2018.58
Data descriptor: Tundra landform and vegetation productivity trend maps for the arctic coastal plain of Northern Alaska
Arctic tundra landscapes are composed of a complex mosaic of patterned ground features, varying in soil moisture, vegetation composition, and surface hydrology over small spatial scales (10-100 m). The importance of microtopography and associated geomorphic landforms in influencing ecosystem structure and function is w...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
10.1163/21540993-00801004
The ʿAjamization Of Islam In Ethiopia Through Esoteric Textual Manifestations In Two Collections Of Ethiopian Arabic Manuscripts
While the word ʿAjamī traditionally refers to texts in many languages written with the modified Arabic script, the meaning has been expanded in the concept of ʿAjamization used in this volume. ʿAjamization is construed in this article, as it is operationalized in the volume, to refer to the various tangible and subtle ...
[ "The Study of the Human Past", "Texts and Concepts" ]
10.1145/1985394.1985399
Evaluating The Compatibility Of Conversational Service Interactions
Service-oriented systems live in an open world, one in which their functionality and quality of service depend on how the services they interact with evolve. System adaptation has been indicated as a way to cope with the evolution these partner services may have. When a partner does not behave as expected, in an adapta...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
2727088
Integration of paper-based nucleic acid testing methods into microfluidic devices for improved biosensing applications
Twelve-member IPANEMA consortium implements competences of participating academic & industry beneficiaries and 3rd country partners to 1) create a knowledge/experience-sharing network of scientists, entrepreneurs & end-users in the multidisciplinary field of biosensors for POCT (point-of care testing); 2) develop innov...
[ "Biotechnology and Biosystems Engineering", "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases", "Environmental Biology, Ecology and Evolution", "Synthetic Chemistry and Materials", "Systems and Communication Engineering" ]
10.1109/ICASSP.2017.7952214
Audio Source Separation Based On Convolutive Transfer Function And Frequency Domain Lasso Optimization
This paper addresses the problem of under-determined convolutive audio source separation in a semi-oracle configuration where the mixing filters are assumed to be known. We propose a separation procedure based on the convolutive transfer function (CTF), which is a more appropriate model for strongly reverberant signals...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
W60672428
The effect of potential large-scale bioreactor environmental heterogeneities during fed-batch culture on the performance of an industrially-relevant GS-CHO cell culture, producing an IgG antibody
This study aimed to study the effect of potential large-scale bioreactor environmental heterogeneities during fed-batch culture on the performance of an industrially-relevant GS-CHO cell culture, producing an IgG antibody. Heterogeneity was created by a two-compartment scale-down model, using a well-mixed stirred tank ...
[ "Biotechnology and Biosystems Engineering", "Products and Processes Engineering", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1093/eurheartj/ehq433
Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy
AimsCurrently, it is still unclear which mechanisms drive metabolic benefits after angiogenic gene therapy. The side-effect profile of efficient angiogenic gene therapy is also currently incompletely understood. In this study, the effects of increasing doses of adenoviral (Ad) vascular endothelial growth factor-A (VEGF...
[ "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
882930
Improving local energy and climate policy through quality management and certification
Climate change is a global problem and to solve it, we need to start on local level. To effectively implement energy and climate policies, concerted and strong action is needed. Municipalities often have ambitious goals and political will, but lack the harmonized, interdepartmental and long-term structures to successfu...
[ "Earth System Science", "Human Mobility, Environment, and Space", "Institutions, Governance and Legal Systems" ]
interreg_2295
Generation in motion
Stura and Ubaye Valley have always been at the heart of a movement of economic migrations: on the Italian side, people moved toward France to find a summer job and from France, itinerant traders were coming in Italy. From this observation, starts the idea of the project: rebuilt the former road of migration, developin...
[ "Human Mobility, Environment, and Space", "The Study of the Human Past" ]
10.1103/PhysRevX.2.011009
First-order 0-π quantum phase transition in the kondo regime of a superconducting carbon-nanotube quantum dot
We study a carbon-nanotube quantum dot embedded in a superconducting-quantum-interference-device loop in order to investigate the competition of strong electron correlations with a proximity effect. Depending on whether local pairing or local magnetism prevails, a superconducting quantum dot will exhibit a positive or ...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
10.3934/dcdss.2013.6.439
Well-posedness of an extended model for water-ice phase transitions
We propose an improved model explaining the occurrence of high stresses due to the difference in specific volumes during phase transitions between water and ice. The unknowns of the resulting evolution problem are the absolute temperature, the volume increment, and the liquid fraction. The main novelty here consists in...
[ "Condensed Matter Physics", "Mathematics" ]
10.1016/j.cobeha.2016.02.028
Multiple channels of visual time perception
The proposal that the processing of visual time might rely on a network of distributed mechanisms that are vision-specific and timescale-specific stands in contrast to the classical view of time perception as the product of a single supramodal clock. Evidence showing that some of these mechanisms have a sensory compone...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1364/CLEO_SI.2017.SM1M.4
All Optically Induced Quasi Phase Matching In Sin Waveguides For Second Harmonic Generation Enhancement
We report more than 30dB second harmonic generation enhancement in SiN waveguide by all-optical writing of a persistent χ(2) grating. Phase matching peaks are observed for different writing wavelengths.
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
W4300496180
Envelhecimento saudável com vitalidade positiva: uma revisão de literatura integrativa
Um breve contexto: O envelhecimento é um processo biológico, natural e comum aos seres vivos. Isso inclui certas mudanças fisiológicas. O advento da globalização possibilitou o aumento da expectativa de vida, neste cenário retratamos o aumento da população idosa, onde o envelhecimento populacional acarreta uma maior ca...
[ "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
218360
Bringing to market an open source cfd framework as a fully automated simulation service with high performance computing cloud-based access
Computational Fluid Dynamics (CFD) uses numerical analysis and algorithms to predict flow with a computer. CFD analyses not only fluid flow behaviour, but also mass, phase change, chemical reactions, mechanical movement, the transfer of heat, and stress/deformation of related solid structures. Rapid progress over the p...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
W1627932336
Distraction produces over-additive increases in the degree to which alcohol impairs driving performance
Research indicates that alcohol intoxication and increased demands on drivers' attention from distractions (e.g., passengers and cell phones) contribute to poor driving performance and increased rates of traffic accidents and fatalities.The present study examined the separate and combined effects of alcohol and distrac...
[ "The Human Mind and Its Complexity", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2011432545
Hydrogen production by oxidative steam reforming of methanol over Ni/CeO2–ZrO2 catalysts
Abstract Single ZrO 2 and mixed CeO 2 –ZrO 2 oxides with different CeO 2 /ZrO 2 ratios were prepared by the sol–gel method and the CeO 2 by precipitation. The prepared support were impregnated with an aqueous solution of NiCl 2 ·6H 2 O at an appropriate concentration to yield 3 wt.% of nickel respectively in the cataly...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Materials Engineering" ]
10.1016/j.tcb.2012.10.012
Resurrecting remnants: The lives of post-mitotic midbodies
Around a century ago, the midbody (MB) was described as a structural assembly within the intercellular bridge during cytokinesis that served to connect the two future daughter cells. The MB has become the focus of intense investigation through the identification of a growing number of diverse cellular and molecular pat...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1152/jn.00112.2017
Task-dependent vestibular feedback responses in reaching
When reaching for an earth-fixed object during self-rotation, the motor system should appropriately integrate vestibular signals and sensory predictions to compensate for the intervening motion and its induced inertial forces. While it is well established that this integration occurs rapidly, it is unknown whether vest...
[ "Neuroscience and Disorders of the Nervous System", "Physiology in Health, Disease and Ageing" ]
10.1016/j.celrep.2018.11.076
An Integrative Study of Protein-RNA Condensates Identifies Scaffolding RNAs and Reveals Players in Fragile X-Associated Tremor/Ataxia Syndrome
Recent evidence indicates that specific RNAs promote the formation of ribonucleoprotein condensates by acting as scaffolds for RNA-binding proteins (RBPs). We systematically investigated RNA-RBP interaction networks to understand ribonucleoprotein assembly. We found that highly contacted RNAs are structured, have long ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Neuroscience and Disorders of the Nervous System", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1017/apr.2016.62
On the evolution of topology in dynamic clique complexes
AbstractWe consider a time varying analogue of the Erdős–Rényi graph and study the topological variations of its associated clique complex. The dynamics of the graph are stationary and are determined by the edges, which evolve independently as continuous-time Markov chains. Our main result is that when the edge inclu...
[ "Mathematics", "Computer Science and Informatics" ]
10.1002/jccs.201500132
Alternative Representations of the Correlation Energy in Density-Functional Theory: A Kinetic-Energy Based Adiabatic Connection
The adiabatic-connection framework has been widely used to explore the properties of the correlation energy in density-functional theory. The integrand in this formula may be expressed in terms of the electron-electron interactions directly, involving intrinsically two-particle expectation values. Alternatively, it may...
[ "Physical and Analytical Chemical Sciences", "Mathematics" ]
10.1111/mec.14056
Plasmid and clonal interference during post horizontal gene transfer evolution
Plasmids are nucleic acid molecules that can drive their own replication in a living cell. They can be transmitted horizontally and can thrive in the host cell to high-copy numbers. Plasmid replication and gene expression consume cellular resources and cells carrying plasmids incur fitness costs. But many plasmids carr...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
US 201113637133 A
NOVEL COMPRESSION TEXTILES
The present invention relates to a compression textile, e.g. a compression bandage or garment, which comprises at least one chitosan-containing fibre. The compression textile is suitable for medical applications, but also for non-medical applications in the field of wellness and sport.
[ "Materials Engineering", "Products and Processes Engineering" ]
W1969218657
Migration of the chest tube into the esophagus in a case of Boerhaave’s syndrome
Boerhaave's syndrome is the spontaneous transmural rupture of the esophagus. Patients can have a variety of manifestations. Boerhaave's syndrome has to be considered in acutely ill patients with no other explanations for their illness. Computed tomography scan of the chest is emerging as a useful tool for the evaluatio...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
646623
Neutrinos and the origin of the cosmic rays
The discovery of cosmic neutrinos is one of the major breakthroughs in science in the year 2013. These neutrinos are expected to point back to the origin of the cosmic rays, which are produced in the most powerful accelerators in the universe. In order to solve the puzzle where the highest energetic neutrinos and cosmi...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]