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int64
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string
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string
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f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
int64
30,576
T
T
C
C
T
C
A
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C
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A
G
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A
A
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A
A
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G
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A
A
A
G
T
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C
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C
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A
C
C
T
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C
C
T
A
A
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G
A
C
C
A
G
A
C
C
A
A
G
G
C
G
G
G
C
A
C
A
T
G
C
G
C
C
T
C
C
T
C
T
T
C
C
T
C
C
T
G
T
T
C
C
A
C
C
C
A
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C
A
T
C
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0
30,581
T
T
T
T
C
C
T
G
T
C
C
C
A
C
A
A
C
T
T
A
G
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T
T
C
C
T
T
A
A
C
A
C
T
T
G
T
T
C
T
A
C
A
G
A
T
G
A
A
A
C
A
A
A
A
A
A
G
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C
C
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C
T
G
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0.068493
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0
30,582
A
G
G
T
C
T
C
T
G
C
T
C
C
T
C
T
G
T
T
C
C
C
A
G
G
G
A
A
G
A
C
T
T
T
C
C
T
G
T
G
G
A
T
C
C
A
A
G
C
T
G
A
T
T
G
G
G
A
T
G
A
A
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G
G
C
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0
30,583
G
G
C
T
G
T
G
C
T
G
G
A
T
G
C
C
A
C
G
C
A
G
A
G
G
C
A
G
C
T
T
A
C
A
G
T
C
A
C
C
G
T
G
A
C
T
G
A
G
A
A
G
T
G
A
G
G
C
C
A
T
G
A
A
C
T
0.033268
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0.050881
0
30,584
C
A
C
A
C
A
C
A
C
A
C
C
T
G
T
C
T
C
T
T
T
A
T
G
T
T
T
T
T
C
T
A
T
A
G
T
T
T
C
C
C
A
T
G
G
T
C
T
C
C
G
T
C
T
T
T
G
T
C
T
T
T
G
C
C
C
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0.027397
0
30,585
A
C
A
T
T
C
T
T
T
C
T
C
A
A
T
T
T
C
T
T
C
C
T
T
A
C
T
T
G
G
A
G
T
C
T
T
A
G
A
T
A
T
A
A
A
C
T
T
G
T
T
T
T
T
G
T
T
T
A
C
A
G
A
T
T
C
0.078278
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0.023483
0
30,586
C
C
C
T
G
T
C
A
T
A
A
T
A
G
A
G
C
A
G
A
G
A
C
A
G
G
G
G
G
C
G
C
C
G
G
G
C
C
G
T
G
G
G
T
A
C
A
C
A
G
C
A
T
G
A
G
C
C
C
C
C
T
C
C
A
T
0.019569
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0.021526
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0.035225
0
30,587
G
A
G
C
T
T
T
A
G
C
A
C
G
G
C
T
T
G
G
G
C
T
A
A
C
C
T
G
G
G
A
A
C
C
C
C
C
C
A
G
A
A
A
C
T
T
G
G
G
A
C
T
C
T
G
G
T
A
G
G
A
A
G
G
T
T
0.02544
0.021526
0.037182
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0.027397
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0.050881
0.043053
0.011742
0.011742
0.033268
0
30,588
C
C
C
T
A
C
T
C
T
T
T
A
G
G
C
A
C
T
A
G
A
G
T
T
G
A
G
G
A
A
T
T
C
T
G
T
T
T
C
C
C
C
A
G
G
T
A
G
G
G
A
T
C
T
C
A
G
T
A
A
G
A
C
A
C
G
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0
30,589
C
G
T
T
C
C
T
A
C
C
C
C
A
C
T
C
C
C
T
T
G
G
T
C
C
C
G
G
C
C
G
G
T
C
G
G
A
G
C
C
T
C
C
C
T
C
C
G
G
G
C
C
T
C
C
A
C
C
C
A
T
C
T
A
A
C
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0.015656
0
30,590
T
G
T
G
T
G
T
G
C
T
G
C
C
C
T
G
G
G
C
C
T
G
A
T
C
T
C
C
A
A
G
C
T
G
A
A
T
T
C
T
T
C
C
A
G
G
G
C
T
C
C
C
C
A
C
T
C
C
A
G
G
C
C
C
T
C
0.029354
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0.027397
0
30,591
G
G
T
G
G
C
A
G
A
G
G
G
C
C
A
T
G
T
C
C
T
A
T
T
T
C
T
G
C
A
G
C
C
T
C
C
C
C
A
A
C
C
A
C
A
C
A
C
A
C
C
T
T
T
C
T
G
C
C
A
G
G
G
C
T
T
0.033268
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0.043053
0.033268
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0.027397
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0.046967
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0.021526
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0.031311
0.052838
0.027397
0.039139
0.058708
0.037182
0.011742
0.023483
0.021526
0
30,592
T
T
G
G
T
C
T
G
G
T
A
G
C
T
T
C
G
G
C
T
G
C
T
G
T
A
A
G
T
G
A
C
C
A
G
T
T
G
T
A
G
T
T
G
C
C
T
G
T
T
G
A
G
T
T
G
G
T
C
C
A
G
C
C
C
A
0.011742
0.02544
0.031311
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0.033268
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0.07045
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0.027397
0.02544
0.046967
0.074364
0.043053
0.011742
0.007828
0.02544
0
30,593
A
C
G
C
G
A
G
C
A
C
C
C
G
G
G
A
C
G
C
G
C
C
C
G
G
C
C
T
C
C
G
G
C
T
A
C
C
T
C
T
T
G
C
G
C
C
G
T
G
G
G
C
G
C
C
C
C
C
G
C
A
A
A
G
C
G
0.013699
0.005871
0.029354
0.001957
0.019569
0.02544
0.011742
0.019569
0.027397
0.056751
0.054795
0
0.017613
0.011742
0.019569
0.046967
0.048924
0.046967
0.097847
0.048924
0.013699
0.076321
0.017613
0.060665
0.015656
0.011742
0.04501
0.076321
0.048924
0.011742
0.001957
0.015656
0
30,594
C
T
C
T
A
C
C
T
T
A
G
C
T
G
G
A
C
C
T
C
G
T
C
T
C
C
C
A
G
G
G
A
T
T
A
G
A
G
A
A
A
A
G
A
G
C
A
G
G
A
G
T
C
C
T
G
G
G
T
C
T
T
C
C
C
C
0.02544
0.019569
0.056751
0.011742
0.021526
0.033268
0.009785
0.041096
0.058708
0.035225
0.060665
0.005871
0.015656
0.013699
0.027397
0.027397
0.066536
0.056751
0.060665
0.005871
0.003914
0
0.019569
0.054795
0.043053
0.043053
0.027397
0.027397
0.064579
0.015656
0.017613
0.029354
0
30,595
C
T
T
G
C
T
C
T
G
T
G
G
C
C
C
A
G
G
C
C
G
G
C
G
T
G
C
A
A
T
G
G
C
A
C
G
A
T
G
T
T
G
G
C
T
C
A
C
T
G
C
A
A
C
C
T
C
C
G
C
C
T
C
C
C
T
0.09002
0.029354
0.029354
0.031311
0.037182
0.023483
0.013699
0.035225
0.029354
0.027397
0.041096
0.013699
0.021526
0.007828
0.041096
0.039139
0.048924
0.04501
0.033268
0.029354
0.015656
0.023483
0.011742
0.043053
0.021526
0.027397
0.019569
0.058708
0.035225
0.013699
0.027397
0.035225
0
30,596
C
A
C
C
T
G
A
A
G
T
G
C
T
C
T
T
A
G
C
A
G
A
A
T
T
A
T
T
T
G
A
A
C
A
G
T
A
T
T
G
C
A
C
A
T
C
T
G
T
A
G
C
T
C
C
T
A
C
C
A
G
C
G
C
T
T
0.050881
0.02544
0.043053
0.02544
0.050881
0.033268
0.007828
0.027397
0.041096
0.048924
0.037182
0.029354
0.023483
0.04501
0.033268
0.035225
0.056751
0.052838
0.029354
0
0
0.003914
0.031311
0.02544
0.031311
0.027397
0.037182
0.019569
0.037182
0.031311
0.029354
0.029354
0
30,597
C
T
T
C
A
G
G
A
G
C
C
T
A
A
G
C
T
G
G
C
A
C
T
T
C
T
G
G
T
T
G
C
T
G
G
T
G
A
A
G
A
A
G
C
T
G
G
A
G
A
A
G
A
A
C
C
C
T
T
G
C
T
G
G
G
A
0.013699
0.021526
0.033268
0.003914
0.015656
0.035225
0.013699
0.013699
0.043053
0.060665
0.060665
0
0.003914
0.015656
0.019569
0.019569
0.078278
0.060665
0.076321
0.033268
0.015656
0.043053
0.011742
0.056751
0.035225
0.033268
0.033268
0.07045
0.048924
0.003914
0.003914
0.021526
0
30,598
A
G
G
T
G
C
C
C
A
C
C
G
T
G
G
C
T
C
T
C
C
T
A
A
G
A
G
T
T
G
T
T
T
T
G
T
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G
C
T
C
A
G
T
G
A
A
G
C
T
C
C
T
C
T
C
T
G
C
C
T
T
G
C
T
A
0.029354
0.02544
0.041096
0.009785
0.037182
0.037182
0.007828
0.027397
0.050881
0.048924
0.054795
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0.015656
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0.02544
0.039139
0.068493
0.054795
0.050881
0.011742
0.003914
0.003914
0.015656
0.056751
0.035225
0.037182
0.029354
0.035225
0.048924
0.009785
0.015656
0.039139
0
30,599
T
T
T
A
G
A
T
T
T
G
C
T
C
A
A
G
G
G
T
T
C
A
G
A
T
T
C
T
C
T
G
G
T
C
T
T
C
T
G
C
C
T
T
G
C
A
T
T
T
T
C
C
T
C
C
T
T
C
C
T
T
T
C
C
T
A
0.105675
0.037182
0.04501
0.074364
0.041096
0.015656
0.005871
0.02544
0.046967
0.021526
0.031311
0.048924
0.027397
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0.001957
0.001957
0.001957
0.02544
0.029354
0.046967
0.013699
0.031311
0.011742
0.027397
0.015656
0.062622
0.041096
0
30,600
C
C
A
G
C
A
G
G
C
A
T
T
C
A
C
C
A
T
T
T
C
T
T
C
C
C
A
A
A
C
A
G
C
C
C
T
A
C
T
A
A
C
T
T
A
A
A
G
G
A
A
A
A
A
A
A
C
A
T
A
C
A
A
T
A
T
0.109589
0.033268
0.048924
0.082192
0.046967
0.013699
0.003914
0.033268
0.046967
0.013699
0.023483
0.07045
0.015656
0.031311
0.031311
0.023483
0.029354
0.023483
0.021526
0.001957
0.001957
0
0.027397
0.011742
0.050881
0.015656
0.017613
0.015656
0.019569
0.02544
0.082192
0.027397
0
30,601
G
T
A
A
A
T
T
A
C
C
T
G
A
T
T
A
T
A
T
T
T
T
G
C
A
T
T
T
G
C
A
A
T
G
T
G
C
T
T
T
G
T
T
T
C
C
A
G
C
T
G
T
C
C
A
T
A
C
T
G
T
G
G
A
G
C
0.101761
0.039139
0.043053
0.064579
0.056751
0.011742
0
0.035225
0.046967
0.021526
0.017613
0.076321
0.02544
0.041096
0.033268
0.017613
0.04501
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0.003914
0.001957
0.001957
0
0.019569
0.015656
0.048924
0.013699
0.023483
0.009785
0.029354
0.033268
0.064579
0.02544
0
30,602
G
C
T
G
G
A
G
T
T
G
C
C
C
G
A
G
G
G
C
C
C
C
G
C
G
T
C
G
G
G
A
C
C
G
G
C
G
G
A
G
A
G
A
C
G
C
A
T
G
C
T
G
T
C
C
A
T
G
C
A
G
C
T
C
C
T
0.013699
0.013699
0.023483
0
0.007828
0.019569
0.031311
0.017613
0.029354
0.066536
0.041096
0
0.009785
0.017613
0.023483
0.027397
0.054795
0.04501
0.064579
0.068493
0.031311
0.062622
0.001957
0.074364
0.013699
0.029354
0.058708
0.082192
0.052838
0.005871
0
0.011742
0
30,603
A
T
A
G
T
A
A
A
A
T
G
G
G
T
A
G
T
A
T
C
C
T
T
C
T
C
A
G
T
T
A
A
C
C
T
T
T
A
A
T
A
C
T
C
T
G
T
A
C
A
C
A
C
T
A
T
T
C
T
G
A
A
A
T
A
T
0.086106
0.023483
0.04501
0.074364
0.054795
0.015656
0.005871
0.027397
0.041096
0.023483
0.02544
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0.011742
0.039139
0.02544
0.021526
0.017613
0.017613
0.031311
0.072407
0.039139
0
30,604
G
C
C
G
G
A
G
G
T
A
G
A
G
G
A
G
G
A
G
A
T
G
G
A
A
A
A
G
T
C
G
G
C
C
C
T
A
G
G
C
G
G
C
G
G
G
A
A
A
C
T
G
C
C
A
A
G
G
G
G
C
T
C
C
T
T
0.027397
0.015656
0.035225
0.011742
0.005871
0.029354
0.009785
0.023483
0.037182
0.043053
0.07045
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0.011742
0.011742
0.023483
0.013699
0.048924
0.039139
0.052838
0.060665
0.021526
0.041096
0.015656
0.074364
0.031311
0.031311
0.033268
0.07045
0.068493
0.007828
0.007828
0.021526
0
30,605
G
C
G
G
C
G
G
C
G
C
C
C
G
A
A
G
A
A
G
A
C
G
T
G
G
T
A
G
G
C
A
G
C
G
T
A
G
A
G
G
G
A
G
A
A
T
A
G
G
C
A
G
T
A
C
A
G
G
G
C
G
A
T
A
A
T
0.007828
0.003914
0.02544
0.005871
0.009785
0.021526
0.017613
0.011742
0.027397
0.048924
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0.009785
0.007828
0.005871
0.013699
0.054795
0.039139
0.103718
0.097847
0.019569
0.088063
0.009785
0.04501
0.02544
0.02544
0.023483
0.117417
0.048924
0.017613
0.003914
0.009785
0
30,606
A
T
C
T
G
G
C
G
A
A
C
T
C
A
A
A
A
A
T
T
C
C
G
G
G
T
A
A
T
C
A
T
C
A
A
T
C
T
G
G
A
A
A
A
A
A
A
A
T
T
A
A
T
T
C
A
C
C
T
C
A
T
T
G
A
T
0.109589
0.029354
0.031311
0.056751
0.029354
0.02544
0.005871
0.031311
0.039139
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0.04501
0.013699
0.023483
0.013699
0.031311
0.02544
0.029354
0.048924
0
30,607
C
G
G
C
T
C
C
A
A
G
T
A
A
G
T
T
C
T
C
A
A
A
T
G
C
T
C
T
T
G
T
C
C
T
A
G
C
T
C
T
T
C
C
C
C
T
T
G
G
A
G
T
C
C
T
G
T
T
T
G
A
C
A
A
T
T
0.058708
0.027397
0.052838
0.043053
0.027397
0.017613
0
0.054795
0.052838
0.031311
0.039139
0.041096
0.023483
0.029354
0.033268
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0.003914
0.003914
0
0.029354
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0.046967
0.023483
0.015656
0.019569
0.043053
0.027397
0.043053
0.046967
0
30,608
C
T
G
G
C
T
T
C
T
C
T
T
C
T
A
G
G
C
T
T
T
T
T
C
A
G
A
A
T
A
T
T
C
T
A
C
C
A
C
T
A
A
T
T
G
T
C
A
A
A
C
A
G
G
A
C
T
C
C
A
A
G
G
G
G
T
0.056751
0.031311
0.058708
0.031311
0.027397
0.019569
0
0.058708
0.048924
0.031311
0.039139
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0.041096
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0.015656
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0
0.023483
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0.043053
0.029354
0.017613
0.021526
0.04501
0.02544
0.039139
0.04501
0
30,609
G
C
T
G
G
C
C
T
C
G
T
T
C
T
G
C
T
C
A
T
C
T
A
T
C
A
G
C
C
C
T
A
C
G
G
T
G
T
C
C
C
C
A
C
A
G
C
C
C
G
G
A
T
G
A
C
T
C
T
T
G
G
T
C
C
T
0.02544
0.031311
0.031311
0.011742
0.037182
0.027397
0.013699
0.027397
0.046967
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0.02544
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0.021526
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0.043053
0.033268
0.037182
0.033268
0.050881
0.013699
0.013699
0.035225
0
30,610
T
C
G
A
G
A
C
C
A
G
C
C
T
G
G
C
C
A
A
C
A
T
G
G
T
G
A
A
A
C
C
C
T
G
T
C
T
C
T
A
C
T
A
A
A
A
A
T
A
C
A
A
A
A
A
T
T
A
G
C
T
G
G
G
T
C
0.07045
0.043053
0.021526
0.035225
0.052838
0.043053
0.005871
0.027397
0.039139
0.02544
0.043053
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0.021526
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0.023483
0.017613
0.027397
0.031311
0.029354
0.029354
0.023483
0.033268
0
30,611
T
T
T
T
A
A
G
C
C
T
G
C
T
G
G
C
C
T
C
C
T
T
T
G
G
G
G
C
A
T
T
C
T
T
T
T
T
T
C
T
C
T
T
T
T
C
A
G
C
A
C
G
C
A
T
C
T
T
T
C
T
T
T
T
C
A
0.146771
0.037182
0.062622
0.023483
0.04501
0.027397
0.005871
0.033268
0.054795
0.021526
0.035225
0.023483
0.023483
0.035225
0.039139
0.039139
0.02544
0.02544
0.009785
0.003914
0
0.001957
0.023483
0.031311
0.043053
0.009785
0.031311
0.021526
0.015656
0.02544
0.041096
0.037182
0
30,612
C
C
T
C
G
G
A
T
C
T
C
T
G
G
G
T
T
T
G
A
T
T
T
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G
C
G
T
T
G
A
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A
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A
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C
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T
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A
A
C
C
T
G
T
C
0.142857
0.037182
0.033268
0.082192
0.037182
0.009785
0.003914
0.043053
0.031311
0.009785
0.027397
0.078278
0.02544
0.02544
0.039139
0.009785
0.029354
0.013699
0.013699
0.003914
0.001957
0.001957
0.023483
0.02544
0.029354
0.011742
0.019569
0.007828
0.027397
0.035225
0.086106
0.033268
0
30,613
A
T
A
A
T
G
C
A
A
C
A
C
A
T
C
C
G
T
A
T
T
T
G
G
A
A
T
C
T
T
T
G
T
A
T
T
T
G
C
A
T
A
C
A
A
C
C
A
C
A
T
G
C
C
A
A
A
A
C
C
C
C
T
G
C
C
0.138943
0.046967
0.058708
0.050881
0.050881
0.013699
0.007828
0.039139
0.050881
0.017613
0.017613
0.027397
0.017613
0.041096
0.056751
0.017613
0.027397
0.021526
0.009785
0.001957
0.001957
0
0.019569
0.019569
0.039139
0.029354
0.039139
0.005871
0.021526
0.017613
0.060665
0.031311
0
30,614
A
T
T
T
T
G
A
A
A
G
C
T
G
A
T
G
G
A
A
G
A
T
T
T
A
A
G
C
A
G
T
A
T
T
C
C
T
T
A
G
G
A
A
G
G
A
A
A
G
T
A
G
G
G
G
G
A
A
G
A
T
A
A
G
T
C
0.086106
0.029354
0.050881
0.058708
0.035225
0.02544
0
0.027397
0.052838
0.023483
0.037182
0.04501
0.031311
0.037182
0.035225
0.023483
0.031311
0.037182
0.015656
0.003914
0.003914
0
0.029354
0.029354
0.064579
0.015656
0.015656
0.007828
0.04501
0.019569
0.043053
0.039139
0
30,615
G
C
C
T
A
C
A
C
A
G
A
A
T
G
G
T
C
A
G
G
A
A
G
A
G
T
T
G
T
T
C
C
T
A
G
A
C
A
A
T
G
A
G
A
T
G
A
G
T
C
T
T
C
C
T
C
T
G
G
A
A
A
A
C
A
C
0.111546
0.041096
0.052838
0.041096
0.050881
0.019569
0.001957
0.043053
0.043053
0.015656
0.029354
0.031311
0.039139
0.04501
0.035225
0.035225
0.029354
0.029354
0.005871
0.001957
0
0
0.023483
0.02544
0.046967
0.017613
0.015656
0.003914
0.037182
0.02544
0.052838
0.048924
0
30,616
C
T
C
C
T
C
T
A
G
C
G
G
C
G
C
A
C
C
T
C
C
A
G
C
A
G
A
T
T
T
T
C
C
G
T
C
C
C
C
A
C
G
G
A
A
G
A
G
C
T
C
T
G
G
A
G
A
C
A
G
T
G
G
A
G
T
0.054795
0.015656
0.02544
0.023483
0.039139
0.029354
0.011742
0.027397
0.043053
0.035225
0.037182
0.013699
0.031311
0.04501
0.02544
0.046967
0.048924
0.04501
0.021526
0.02544
0.013699
0.023483
0.017613
0.050881
0.033268
0.031311
0.037182
0.033268
0.04501
0.013699
0.009785
0.04501
0
30,617
G
A
A
G
A
G
C
T
C
T
G
G
A
G
A
C
A
G
T
G
G
A
G
G
A
C
C
C
A
G
C
A
C
A
C
C
G
T
C
A
G
C
A
T
C
T
C
C
A
C
T
C
C
C
T
G
T
A
G
T
C
A
C
A
G
T
0.062622
0.021526
0.02544
0.02544
0.041096
0.027397
0.011742
0.029354
0.041096
0.033268
0.033268
0.011742
0.033268
0.050881
0.027397
0.04501
0.04501
0.046967
0.019569
0.023483
0.011742
0.023483
0.017613
0.048924
0.033268
0.027397
0.033268
0.031311
0.04501
0.015656
0.011742
0.04501
0
30,618
A
T
G
G
G
T
C
T
G
C
A
A
T
A
G
A
C
A
C
C
A
G
C
T
A
T
G
G
A
A
C
T
C
A
A
G
G
T
A
T
G
T
C
T
T
T
A
C
T
T
T
G
T
C
C
C
C
C
A
G
A
G
G
A
C
G
0.039139
0.017613
0.048924
0.033268
0.039139
0.023483
0.001957
0.039139
0.043053
0.035225
0.035225
0.041096
0.023483
0.052838
0.033268
0.033268
0.041096
0.056751
0.033268
0.003914
0.005871
0
0.021526
0.041096
0.033268
0.027397
0.033268
0.029354
0.043053
0.02544
0.033268
0.031311
0
30,619
A
G
A
G
A
A
T
A
A
T
G
A
A
A
G
C
T
T
A
C
C
A
C
T
A
T
T
T
G
A
C
T
T
A
G
C
A
A
G
A
A
A
T
T
C
A
A
G
A
G
G
A
C
T
C
T
G
A
T
C
C
A
G
G
T
C
0.093933
0.023483
0.060665
0.07045
0.019569
0.005871
0.001957
0.039139
0.050881
0.037182
0.015656
0.058708
0.041096
0.037182
0.033268
0.013699
0.035225
0.029354
0.007828
0.005871
0.001957
0.001957
0.017613
0.029354
0.050881
0.007828
0.023483
0.017613
0.029354
0.021526
0.07045
0.046967
0
30,620
C
A
A
A
G
T
C
A
A
G
C
A
T
C
T
A
A
T
A
A
T
T
A
A
C
A
G
C
A
T
A
C
C
G
A
A
G
T
T
T
A
C
A
C
A
C
A
C
G
T
T
A
A
A
A
A
C
A
A
G
T
A
A
A
T
T
0.074364
0.035225
0.043053
0.046967
0.043053
0.02544
0.005871
0.031311
0.041096
0.021526
0.037182
0.037182
0.035225
0.04501
0.041096
0.029354
0.041096
0.041096
0.009785
0.001957
0.009785
0.001957
0.019569
0.029354
0.048924
0.011742
0.033268
0.021526
0.033268
0.029354
0.035225
0.039139
0
30,621
A
G
T
G
T
C
T
C
C
A
T
C
T
A
A
G
A
T
G
A
A
G
C
C
T
C
C
A
G
C
C
C
C
A
G
A
A
C
A
G
A
G
G
A
A
A
A
G
A
A
T
G
A
C
C
T
C
T
C
A
G
G
A
T
T
T
0.09002
0.037182
0.043053
0.048924
0.041096
0.021526
0.005871
0.029354
0.056751
0.027397
0.035225
0.023483
0.039139
0.04501
0.029354
0.019569
0.037182
0.027397
0.011742
0.007828
0.001957
0
0.033268
0.035225
0.043053
0.015656
0.017613
0.017613
0.031311
0.027397
0.056751
0.043053
0
30,622
A
G
C
A
A
G
A
T
C
T
A
A
T
G
C
T
C
T
G
A
T
G
T
T
G
C
T
A
C
T
A
A
C
G
G
T
T
C
C
T
T
C
T
G
A
G
C
T
T
G
T
G
G
T
T
G
A
G
G
A
G
A
C
A
T
T
0.086106
0.029354
0.039139
0.054795
0.04501
0.015656
0.003914
0.02544
0.048924
0.037182
0.02544
0.054795
0.037182
0.04501
0.043053
0.017613
0.037182
0.02544
0.011742
0.005871
0.009785
0.003914
0.033268
0.029354
0.043053
0.021526
0.029354
0.011742
0.029354
0.021526
0.035225
0.043053
0
30,623
A
A
A
A
T
C
A
C
A
A
G
A
A
G
C
A
G
A
A
C
A
A
A
A
G
G
A
T
G
T
T
A
C
T
C
A
A
G
A
A
A
G
A
G
T
T
C
A
C
T
C
A
C
T
A
G
A
A
G
C
T
T
C
C
A
T
0.088063
0.039139
0.052838
0.041096
0.041096
0.031311
0.003914
0.033268
0.066536
0.029354
0.017613
0.021526
0.021526
0.041096
0.041096
0.035225
0.033268
0.04501
0.021526
0.005871
0.001957
0
0.023483
0.035225
0.068493
0.009785
0.023483
0.009785
0.027397
0.02544
0.023483
0.041096
0
30,624
C
A
G
T
C
T
T
C
A
A
A
A
A
C
G
C
T
T
C
C
A
T
C
C
C
T
T
C
C
T
G
G
C
G
G
T
G
G
T
A
G
T
T
G
A
A
A
T
C
C
A
G
C
G
C
A
G
C
T
A
C
C
A
A
A
T
0.043053
0.037182
0.037182
0.015656
0.037182
0.037182
0.021526
0.033268
0.041096
0.037182
0.04501
0.011742
0.009785
0.017613
0.035225
0.041096
0.052838
0.035225
0.039139
0.029354
0.007828
0.015656
0.021526
0.04501
0.043053
0.027397
0.039139
0.029354
0.041096
0.02544
0.011742
0.035225
0
30,625
G
A
A
T
G
A
G
T
G
G
A
A
G
A
T
G
G
A
A
G
A
T
A
T
A
A
A
A
A
T
C
C
C
A
C
T
C
C
C
T
C
A
G
C
C
T
C
A
A
T
T
C
C
A
G
T
G
T
G
C
T
A
A
G
A
T
0.064579
0.033268
0.048924
0.046967
0.050881
0.027397
0.003914
0.029354
0.054795
0.021526
0.035225
0.015656
0.02544
0.04501
0.031311
0.048924
0.037182
0.048924
0.019569
0
0.005871
0.001957
0.017613
0.039139
0.060665
0.005871
0.029354
0.017613
0.039139
0.023483
0.037182
0.033268
0
30,626
T
G
T
A
C
A
G
G
G
A
A
T
T
T
A
T
T
G
T
T
T
T
T
G
C
T
G
T
T
C
T
T
T
A
T
A
C
A
G
C
A
A
T
A
A
G
T
T
T
G
G
T
A
T
A
C
A
G
G
T
A
C
T
T
T
C
0.091977
0.031311
0.048924
0.04501
0.048924
0.017613
0.001957
0.043053
0.048924
0.021526
0.033268
0.041096
0.029354
0.033268
0.048924
0.019569
0.043053
0.031311
0.011742
0
0.001957
0.003914
0.02544
0.029354
0.033268
0.021526
0.027397
0.021526
0.027397
0.039139
0.043053
0.035225
0
30,627
A
C
A
C
A
G
T
C
C
C
T
G
A
C
C
T
T
A
A
A
G
A
T
T
T
G
T
C
A
G
T
G
T
T
T
T
T
A
G
C
C
A
T
T
G
G
C
C
A
T
A
C
T
G
A
A
A
T
C
T
T
C
A
T
G
C
0.088063
0.037182
0.052838
0.060665
0.046967
0.013699
0
0.033268
0.043053
0.021526
0.033268
0.021526
0.029354
0.039139
0.062622
0.019569
0.035225
0.046967
0.019569
0
0
0
0.015656
0.027397
0.048924
0.017613
0.021526
0.027397
0.039139
0.019569
0.037182
0.041096
0
30,628
T
A
T
G
T
T
T
C
C
A
T
A
G
T
A
A
A
A
G
G
G
G
A
A
C
C
A
A
A
G
G
G
C
T
G
G
A
A
A
G
C
C
A
C
A
G
A
G
A
A
A
T
C
T
C
C
C
A
G
G
A
G
A
T
G
A
0.048924
0.031311
0.054795
0.031311
0.048924
0.015656
0.003914
0.027397
0.050881
0.041096
0.048924
0.027397
0.031311
0.027397
0.050881
0.031311
0.041096
0.039139
0.029354
0.003914
0.001957
0.001957
0.031311
0.041096
0.050881
0.013699
0.027397
0.031311
0.04501
0.019569
0.015656
0.035225
0
30,629
G
A
C
T
C
C
T
G
G
T
G
G
G
G
G
A
G
A
C
G
T
T
G
A
T
T
C
C
T
A
C
A
C
G
G
T
G
T
C
G
G
C
A
T
T
C
A
G
G
C
A
C
A
G
T
C
A
A
A
A
G
G
T
T
G
T
0.074364
0.033268
0.02544
0.048924
0.039139
0.021526
0.017613
0.037182
0.046967
0.02544
0.02544
0.013699
0.02544
0.033268
0.039139
0.041096
0.050881
0.039139
0.027397
0.015656
0.001957
0.003914
0.021526
0.037182
0.052838
0.029354
0.02544
0.023483
0.035225
0.011742
0.015656
0.060665
0
30,630
T
G
G
G
A
G
C
A
G
T
A
T
C
G
G
A
T
C
C
T
A
C
T
C
T
T
C
A
A
T
G
A
T
T
C
T
G
T
G
G
T
G
C
T
G
C
T
C
A
A
C
A
T
C
A
C
T
G
T
G
G
G
A
A
A
G
0.046967
0.033268
0.033268
0.039139
0.04501
0.029354
0.009785
0.037182
0.04501
0.019569
0.039139
0.033268
0.031311
0.037182
0.043053
0.02544
0.052838
0.037182
0.029354
0.011742
0.005871
0.003914
0.015656
0.039139
0.037182
0.02544
0.033268
0.017613
0.041096
0.037182
0.023483
0.041096
0
30,631
C
C
A
C
T
G
T
T
C
T
C
T
C
T
T
C
A
T
C
C
A
G
A
G
A
A
A
T
A
A
T
C
C
T
G
A
A
G
T
T
A
T
A
G
A
T
G
G
T
T
C
C
T
G
C
T
T
G
T
A
A
A
T
C
T
T
0.052838
0.031311
0.043053
0.029354
0.046967
0.031311
0.005871
0.027397
0.048924
0.029354
0.043053
0.02544
0.031311
0.023483
0.037182
0.035225
0.058708
0.050881
0.027397
0.013699
0.003914
0.007828
0.019569
0.029354
0.041096
0.02544
0.023483
0.037182
0.041096
0.019569
0.02544
0.033268
0
30,632
C
A
G
T
G
C
A
G
A
T
T
T
A
A
C
A
T
G
A
A
G
G
A
G
C
T
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T
T
C
A
T
C
C
T
C
A
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T
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C
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C
A
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C
C
A
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T
G
C
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G
T
T
C
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G
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30,633
T
T
C
A
C
T
T
T
G
G
A
G
T
A
A
A
T
G
T
G
A
A
C
T
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C
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A
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G
T
C
C
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C
A
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C
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G
A
G
A
C
C
T
T
G
T
G
A
G
A
A
T
T
C
G
G
C
T
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30,634
T
G
G
C
A
A
A
A
A
A
T
T
T
G
A
T
T
A
T
A
G
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A
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A
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C
A
G
T
T
A
T
T
G
A
G
G
T
A
C
A
G
T
A
T
G
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30,635
T
G
C
A
G
C
G
A
C
T
T
T
C
T
T
T
T
A
T
A
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C
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C
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G
A
A
T
C
A
T
G
A
T
G
A
T
G
G
C
A
C
C
T
G
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0
30,636
T
A
C
T
C
T
G
G
C
A
G
C
C
C
T
G
G
A
G
C
G
T
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A
A
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A
A
A
A
T
T
T
G
A
A
A
C
G
A
A
A
G
C
T
C
C
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0
30,637
C
T
T
C
C
C
A
A
A
T
C
A
A
G
T
C
G
T
G
G
G
A
C
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A
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A
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T
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T
C
C
C
G
T
A
A
C
T
T
T
T
T
A
A
C
A
T
G
A
0.099804
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0.097847
0.035225
0
30,638
G
T
T
C
A
A
T
T
T
T
G
C
C
C
T
A
A
A
G
T
T
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A
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C
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C
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A
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G
G
A
G
C
A
C
A
T
T
T
T
A
T
A
T
G
C
A
A
T
0.105675
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0
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0.023483
0.013699
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0.027397
0.062622
0.021526
0
30,639
G
G
A
A
A
G
A
A
A
C
A
G
G
C
T
A
A
C
T
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A
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C
A
A
T
T
C
C
A
C
T
G
C
T
T
A
T
T
C
A
A
T
0.068493
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0.015656
0.023483
0.043053
0.046967
0.037182
0
30,640
T
G
G
C
A
A
G
G
A
A
T
G
G
A
A
G
A
T
G
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A
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C
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A
A
G
G
T
T
A
A
G
G
A
A
T
C
T
A
A
A
G
A
C
0.129159
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0
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0
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0.027397
0.09589
0.029354
0
30,641
C
A
T
G
A
C
A
T
C
C
G
G
T
C
T
C
C
A
A
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G
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A
A
T
C
A
C
T
T
G
C
T
T
T
T
G
A
G
A
A
C
G
0.103718
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0.031311
0.054795
0.017613
0.02544
0.011742
0.023483
0.021526
0.058708
0.052838
0
30,642
G
T
G
G
G
A
C
A
T
C
C
A
G
T
C
T
C
A
G
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G
A
A
G
T
T
T
C
C
T
G
A
A
G
A
C
A
C
T
G
A
0.050881
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0.054795
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0
0.027397
0.041096
0.027397
0.046967
0.019569
0.029354
0.037182
0.015656
0.037182
0.046967
0
30,643
C
T
C
C
A
G
A
A
A
G
A
A
A
T
C
C
C
A
T
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C
A
A
G
C
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C
A
T
G
G
A
C
A
C
0.107632
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0.04501
0.054795
0.031311
0.019569
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0.039139
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0.029354
0.02544
0.009785
0.013699
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0.02544
0.023483
0.04501
0.023483
0.019569
0.013699
0.037182
0.021526
0.046967
0.039139
0
30,644
C
G
A
G
C
T
C
A
A
C
A
A
C
A
A
C
C
T
C
C
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G
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C
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C
G
T
C
C
C
C
G
G
T
C
C
C
G
G
G
G
G
C
G
G
0.005871
0.013699
0.02544
0.001957
0.005871
0.029354
0.021526
0.007828
0.02544
0.052838
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0.007828
0.015656
0.021526
0.04501
0.035225
0.109589
0.109589
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0.086106
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0.046967
0.02544
0.027397
0.041096
0.109589
0.043053
0.001957
0
0.007828
0
30,645
G
T
T
G
A
C
T
T
C
T
A
A
A
A
T
A
C
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T
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C
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C
A
A
C
T
A
T
C
T
C
C
A
A
A
T
A
C
C
C
G
A
0.119374
0.031311
0.041096
0.09002
0.037182
0.015656
0
0.033268
0.039139
0.015656
0.021526
0.088063
0.02544
0.050881
0.031311
0.017613
0.015656
0.013699
0.005871
0.001957
0.001957
0
0.029354
0.023483
0.046967
0.013699
0.011742
0.003914
0.017613
0.023483
0.082192
0.050881
0
30,646
A
A
T
G
G
T
T
C
T
A
T
G
G
A
C
A
C
A
C
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A
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G
T
G
T
G
T
G
C
A
A
A
G
T
T
G
G
A
A
C
T
G
0.103718
0.041096
0.054795
0.058708
0.056751
0.013699
0
0.037182
0.060665
0.011742
0.02544
0.033268
0.019569
0.029354
0.054795
0.031311
0.031311
0.023483
0.011742
0.003914
0.001957
0.001957
0.023483
0.02544
0.058708
0.019569
0.029354
0.015656
0.023483
0.017613
0.043053
0.037182
0
30,647
A
A
T
G
C
A
C
T
G
G
G
C
T
G
A
A
T
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T
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C
A
C
A
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A
G
T
C
T
T
C
T
C
T
T
A
C
0.103718
0.041096
0.056751
0.060665
0.058708
0.013699
0
0.033268
0.060665
0.015656
0.02544
0.035225
0.021526
0.027397
0.054795
0.031311
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0.021526
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0.023483
0.023483
0.058708
0.017613
0.029354
0.015656
0.021526
0.015656
0.04501
0.037182
0
30,648
A
T
G
T
G
T
T
C
T
T
A
C
C
A
C
T
T
C
A
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T
T
A
C
A
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A
A
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G
G
C
A
A
A
C
0.101761
0.037182
0.041096
0.093933
0.04501
0.017613
0
0.037182
0.048924
0.005871
0.015656
0.072407
0.031311
0.04501
0.041096
0.021526
0.019569
0.019569
0.005871
0
0
0
0.029354
0.015656
0.041096
0.009785
0.021526
0.011742
0.007828
0.031311
0.09002
0.041096
0
30,649
A
G
A
C
A
C
T
C
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C
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G
A
T
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C
A
G
G
A
T
T
C
A
A
A
0.097847
0.031311
0.037182
0.084149
0.04501
0.007828
0.007828
0.048924
0.041096
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0.029354
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0.056751
0.011742
0.011742
0.009785
0.021526
0.041096
0.052838
0.04501
0
30,650
A
T
G
G
T
T
A
T
C
T
T
T
T
T
C
T
T
C
C
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A
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C
A
T
0.101761
0.033268
0.041096
0.080235
0.04501
0.007828
0.007828
0.048924
0.043053
0.003914
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0.019569
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0.001957
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0.001957
0.02544
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0.058708
0.013699
0.011742
0.009785
0.019569
0.035225
0.052838
0.046967
0
30,651
A
G
T
G
C
T
A
A
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A
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G
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T
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G
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A
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T
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C
0.091977
0.027397
0.04501
0.074364
0.050881
0.017613
0
0.035225
0.043053
0.019569
0.035225
0.043053
0.011742
0.056751
0.02544
0.029354
0.031311
0.021526
0.007828
0
0
0
0.02544
0.029354
0.043053
0.029354
0.029354
0.009785
0.029354
0.017613
0.078278
0.041096
0
30,652
G
C
A
C
T
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T
T
C
A
C
T
T
G
A
A
A
C
A
T
G
T
A
G
C
0.117417
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0
0.037182
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0.035225
0.009785
0.017613
0.013699
0.017613
0.039139
0.080235
0.039139
0
30,653
T
T
T
T
C
T
T
T
T
A
C
T
T
T
T
T
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T
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G
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T
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A
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A
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A
A
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A
A
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A
A
T
0.101761
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0
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0.017613
0.017613
0.019569
0.013699
0.033268
0.066536
0.04501
0
30,654
T
T
A
T
A
C
A
A
C
A
T
A
T
C
T
T
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A
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A
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T
T
A
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A
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A
T
A
G
T
A
C
G
A
T
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0
0.007828
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0.048924
0.007828
0.009785
0.007828
0.015656
0.041096
0.054795
0.043053
0
30,655
T
T
A
T
T
C
C
T
G
T
C
T
C
T
G
G
A
A
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A
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C
C
A
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G
T
T
G
T
C
G
T
T
0.097847
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0.058708
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0.027397
0.013699
0.019569
0.02544
0.058708
0.029354
0
30,656
T
C
C
T
T
C
C
C
C
C
A
A
G
T
A
G
T
C
C
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T
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A
T
C
T
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A
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A
G
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A
G
T
A
A
T
A
0.099804
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0.035225
0.099804
0.035225
0.017613
0.001957
0.035225
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0
0.001957
0
0.037182
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0.052838
0.009785
0.023483
0.003914
0.021526
0.033268
0.066536
0.039139
0
30,657
T
T
T
G
C
C
C
A
T
T
A
C
C
T
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A
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T
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A
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C
C
A
T
T
T
C
G
C
0.082192
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0.02544
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0.029354
0.046967
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0.027397
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0.005871
0.005871
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0.02544
0.02544
0.037182
0.015656
0.019569
0.011742
0.015656
0.033268
0.062622
0.046967
0
30,658
A
A
C
A
T
A
G
T
A
G
A
A
G
A
C
T
A
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A
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C
T
T
A
C
A
T
T
T
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T
T
G
C
A
G
T
T
G
G
0.07045
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0.039139
0.015656
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0.005871
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0.035225
0.019569
0.021526
0.013699
0.013699
0.035225
0.060665
0.04501
0
30,659
T
T
A
C
C
G
A
G
A
A
G
A
T
G
A
T
C
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A
T
A
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A
G
A
A
A
A
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C
A
A
C
A
C
0.105675
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0
0.017613
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0.027397
0.033268
0.058708
0.043053
0
30,660
A
G
A
C
A
G
T
G
C
T
G
G
C
T
G
C
G
C
T
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A
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C
C
C
T
G
C
C
C
T
C
A
G
A
G
A
C
G
C
G
C
G
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0.058708
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0.001957
0.021526
0
30,661
G
C
T
G
A
G
G
A
A
G
T
C
A
G
C
G
T
C
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G
C
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C
C
C
C
C
T
A
G
T
G
G
A
A
G
C
A
G
G
0.013699
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0.033268
0.029354
0.04501
0.054795
0.060665
0.009785
0.001957
0.019569
0
30,662
C
C
G
C
G
G
C
T
T
C
A
T
T
C
T
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G
A
A
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A
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A
A
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A
A
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C
T
C
T
G
G
A
C
A
C
A
C
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0.054795
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0
0.007828
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0.029354
0.043053
0
30,663
A
T
G
A
A
G
T
G
T
T
A
T
G
T
G
T
G
A
T
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C
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T
T
G
A
G
A
G
A
G
G
G
A
T
G
A
A
T
C
C
A
A
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0
0.043053
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0
0
0
0.031311
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0.013699
0.019569
0.017613
0.019569
0.019569
0.066536
0.04501
0
30,664
G
C
A
T
A
T
G
A
T
T
A
T
T
A
G
A
A
A
C
T
G
C
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C
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A
A
A
A
A
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G
T
A
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A
T
A
A
C
T
T
C
T
0.101761
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0.041096
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0.02544
0.011742
0
0.039139
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0.013699
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0
0
0
0.029354
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0.056751
0.005871
0.015656
0.005871
0.009785
0.02544
0.088063
0.050881
0
30,665
A
G
T
G
G
A
G
G
T
G
C
C
C
A
A
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T
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A
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C
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T
T
T
T
T
C
T
T
C
C
A
G
A
A
A
G
A
A
G
G
T
0.121331
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0
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0.019569
0.013699
0.041096
0.02544
0.066536
0.021526
0
30,666
G
C
A
A
A
C
A
C
T
T
T
T
T
A
C
C
T
C
T
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A
A
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A
G
T
A
T
T
C
G
G
T
A
A
T
A
T
T
T
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0.076321
0.011742
0.033268
0.007828
0.033268
0.011742
0.027397
0.068493
0
30,667
T
A
T
G
C
C
T
A
G
C
A
A
A
C
A
A
A
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G
A
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A
G
A
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A
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A
A
A
T
G
G
A
A
G
0.107632
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0.046967
0.066536
0.050881
0.011742
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0.031311
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0
0.02544
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0.015656
0.02544
0.011742
0.037182
0.033268
0.043053
0.039139
0
30,668
G
A
A
A
T
A
T
C
A
A
A
T
A
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A
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A
G
A
C
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C
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T
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G
G
A
A
A
G
T
T
C
T
G
T
G
G
T
T
C
A
C
0.107632
0.02544
0.048924
0.074364
0.041096
0.023483
0.003914
0.029354
0.048924
0.015656
0.029354
0.052838
0.027397
0.04501
0.029354
0.035225
0.02544
0.023483
0.009785
0
0
0
0.023483
0.02544
0.050881
0.011742
0.02544
0.009785
0.019569
0.02544
0.066536
0.04501
0
30,669
T
T
T
A
C
C
C
T
C
T
T
T
G
C
A
A
T
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T
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A
A
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A
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A
T
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C
G
0.091977
0.02544
0.054795
0.07045
0.031311
0.033268
0.005871
0.029354
0.046967
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0
0.029354
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0.056751
0.007828
0.035225
0.015656
0.02544
0.029354
0.058708
0.027397
0
30,670
C
T
C
A
A
G
T
T
T
T
C
T
C
T
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G
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A
C
T
A
A
C
0.154599
0.043053
0.052838
0.072407
0.046967
0.007828
0
0.037182
0.04501
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0
0.031311
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0.007828
0.031311
0.003914
0.019569
0.029354
0.066536
0.035225
0
30,671
C
A
T
T
T
C
T
A
A
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T
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A
C
0.129159
0.015656
0.048924
0.105675
0.023483
0.009785
0
0.023483
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0.029354
0.011742
0.017613
0.019569
0.091977
0.033268
0
30,672
C
A
G
G
T
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C
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A
G
A
C
C
A
A
T
C
T
A
G
A
C
G
G
C
T
C
G
G
0.021526
0.035225
0.043053
0.017613
0.033268
0.027397
0.019569
0.031311
0.046967
0.043053
0.029354
0.011742
0.02544
0.019569
0.039139
0.029354
0.04501
0.04501
0.039139
0.037182
0.031311
0.021526
0.02544
0.037182
0.04501
0.027397
0.037182
0.043053
0.041096
0.019569
0.013699
0.017613
0
30,673
T
G
A
T
T
G
G
A
A
T
A
C
T
T
T
T
G
A
A
T
T
C
T
A
T
A
T
G
C
A
G
A
T
A
G
G
G
G
A
G
C
C
C
A
T
G
A
T
T
G
G
T
G
G
G
T
T
T
G
A
C
T
G
G
C
C
0.04501
0.029354
0.033268
0.046967
0.04501
0.027397
0.013699
0.031311
0.029354
0.02544
0.035225
0.027397
0.035225
0.023483
0.052838
0.043053
0.048924
0.058708
0.041096
0.009785
0.003914
0.011742
0.015656
0.023483
0.039139
0.029354
0.017613
0.027397
0.048924
0.017613
0.017613
0.04501
0
30,674
C
G
G
C
C
T
C
T
T
G
C
T
G
C
T
T
T
T
T
C
A
G
G
T
C
T
A
A
T
T
G
A
T
C
G
G
T
C
G
G
G
A
G
T
T
T
G
T
G
A
T
G
T
G
T
T
T
C
C
A
A
G
A
C
T
G
0.099804
0.021526
0.074364
0.041096
0.033268
0.023483
0.001957
0.023483
0.066536
0.023483
0.037182
0.013699
0.023483
0.027397
0.046967
0.027397
0.029354
0.041096
0.033268
0.011742
0.005871
0
0.011742
0.035225
0.064579
0.02544
0.02544
0.021526
0.04501
0.009785
0.023483
0.031311
0
30,675
A
C
T
T
A
A
A
G
T
T
T
C
A
A
A
A
T
C
T
T
G
T
T
T
C
A
G
G
A
T
T
T
T
T
T
T
T
T
C
T
T
C
C
T
C
T
T
G
C
T
T
G
G
T
A
A
G
C
T
T
T
T
G
C
T
G
0.154599
0.037182
0.064579
0.074364
0.039139
0.009785
0
0.046967
0.050881
0.023483
0.013699
0.031311
0.029354
0.013699
0.050881
0.015656
0.029354
0.015656
0.001957
0.001957
0.001957
0.003914
0.02544
0.015656
0.066536
0.007828
0.007828
0.003914
0.017613
0.035225
0.060665
0.048924
0