Datasets:
TabBioMed
/
vep_pathogenic_coding

Dataset card Data Studio Files
xet
 Community
row_idx
int64
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f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
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4,561
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C
A
C
C
A
G
G
C
T
C
C
C
C
C
T
G
G
T
0.015656
0.007828
0.033268
0.001957
0.035225
0.037182
0.009785
0.019569
0.02544
0.029354
0.07045
0
0.017613
0.039139
0.021526
0.043053
0.056751
0.064579
0.133072
0.019569
0.009785
0.003914
0.009785
0.043053
0.017613
0.037182
0.027397
0.072407
0.046967
0.013699
0.003914
0.033268
1
4,564
A
C
T
C
A
C
C
A
T
C
T
C
T
C
C
T
T
T
G
T
G
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G
G
G
A
C
C
A
G
C
T
T
C
T
C
C
C
T
G
C
A
T
0.019569
0.009785
0.035225
0.003914
0.035225
0.031311
0.011742
0.023483
0.033268
0.029354
0.072407
0
0.017613
0.029354
0.017613
0.04501
0.060665
0.054795
0.117417
0.021526
0.005871
0.003914
0.009785
0.050881
0.029354
0.033268
0.019569
0.068493
0.048924
0.013699
0.003914
0.043053
1
4,565
C
T
C
T
C
C
A
T
C
A
A
G
G
C
C
A
C
A
G
G
C
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C
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T
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C
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G
A
G
G
G
A
G
A
A
A
A
G
C
A
G
A
T
G
A
A
G
G
0.039139
0.019569
0.039139
0.009785
0.02544
0.033268
0.011742
0.019569
0.04501
0.02544
0.074364
0.003914
0.017613
0.023483
0.021526
0.037182
0.054795
0.050881
0.103718
0.017613
0.003914
0.005871
0.013699
0.056751
0.039139
0.023483
0.015656
0.062622
0.043053
0.009785
0.007828
0.04501
1
4,566
C
T
T
C
T
T
C
A
T
C
T
G
C
T
T
T
T
C
T
C
C
C
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A
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G
A
G
C
C
T
G
T
G
G
C
C
T
T
G
A
T
G
G
A
T
0.039139
0.019569
0.039139
0.009785
0.02544
0.033268
0.011742
0.019569
0.04501
0.02544
0.072407
0.005871
0.019569
0.023483
0.021526
0.037182
0.052838
0.048924
0.103718
0.017613
0.003914
0.005871
0.013699
0.056751
0.039139
0.023483
0.015656
0.062622
0.04501
0.009785
0.007828
0.04501
1
4,567
A
A
A
A
C
C
A
A
T
C
T
T
G
T
T
T
C
T
T
T
C
C
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A
C
C
T
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G
A
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A
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A
T
G
A
A
G
C
C
A
A
C
A
T
C
T
C
C
T
T
T
T
T
0.031311
0.019569
0.035225
0.009785
0.023483
0.046967
0.001957
0.02544
0.043053
0.017613
0.082192
0.011742
0.02544
0.031311
0.021526
0.037182
0.048924
0.056751
0.080235
0.009785
0.005871
0.005871
0.023483
0.060665
0.037182
0.031311
0.011742
0.043053
0.058708
0.009785
0.005871
0.046967
1
4,568
A
A
A
C
C
A
A
T
C
T
T
G
T
T
T
C
T
T
T
C
C
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A
C
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T
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G
A
G
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C
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C
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G
A
A
G
C
C
A
A
C
A
T
C
T
C
C
T
T
T
T
T
A
0.031311
0.019569
0.035225
0.009785
0.023483
0.046967
0.001957
0.02544
0.043053
0.017613
0.082192
0.011742
0.02544
0.031311
0.021526
0.039139
0.048924
0.056751
0.080235
0.009785
0.005871
0.005871
0.023483
0.060665
0.037182
0.029354
0.011742
0.043053
0.058708
0.009785
0.005871
0.046967
1
4,569
A
C
C
A
A
T
C
T
T
G
T
T
T
C
T
T
T
C
C
T
A
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T
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G
A
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A
G
C
C
A
A
C
A
T
C
T
C
C
T
T
T
T
T
C
T
T
0.031311
0.019569
0.035225
0.009785
0.023483
0.046967
0.001957
0.02544
0.041096
0.017613
0.082192
0.011742
0.02544
0.031311
0.021526
0.039139
0.048924
0.058708
0.080235
0.009785
0.005871
0.005871
0.023483
0.058708
0.037182
0.029354
0.011742
0.043053
0.060665
0.009785
0.005871
0.046967
1
4,570
G
G
T
C
A
C
C
A
G
G
G
A
T
C
C
C
T
G
C
T
G
C
A
C
C
A
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G
T
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G
A
C
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G
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C
A
C
A
G
A
T
G
G
G
G
G
A
G
C
C
C
T
T
C
A
T
0.005871
0.011742
0.019569
0
0.050881
0.046967
0.001957
0.021526
0.023483
0.033268
0.054795
0.011742
0.021526
0.041096
0.013699
0.07045
0.074364
0.084149
0.117417
0.019569
0
0.005871
0.009785
0.029354
0.009785
0.033268
0.033268
0.072407
0.037182
0.005871
0.007828
0.031311
1
4,571
G
T
G
A
C
A
A
G
G
G
C
T
C
A
G
C
C
G
G
G
T
T
G
C
C
A
G
G
A
C
T
G
C
G
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G
G
A
C
T
C
C
T
G
G
G
A
C
C
C
C
A
G
G
C
A
A
G
T
T
C
T
G
C
C
T
0.001957
0.015656
0.019569
0.005871
0.041096
0.023483
0.009785
0.031311
0.029354
0.050881
0.048924
0.007828
0.019569
0.021526
0.017613
0.052838
0.088063
0.076321
0.099804
0.023483
0.003914
0.009785
0.009785
0.041096
0.017613
0.033268
0.033268
0.078278
0.048924
0.003914
0.005871
0.029354
1
4,572
G
G
G
T
C
C
C
A
G
G
A
G
T
C
C
A
C
G
C
A
G
T
C
C
T
G
G
C
A
A
C
C
C
G
G
C
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G
A
G
C
C
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T
G
T
C
A
C
C
A
G
G
C
T
C
T
C
C
C
T
T
G
C
T
0.001957
0.015656
0.021526
0.005871
0.041096
0.023483
0.009785
0.031311
0.029354
0.048924
0.050881
0.007828
0.017613
0.019569
0.019569
0.052838
0.088063
0.074364
0.097847
0.02544
0.003914
0.011742
0.009785
0.041096
0.015656
0.033268
0.035225
0.080235
0.046967
0.003914
0.005871
0.029354
1
4,573
C
T
G
A
G
C
C
C
T
T
G
T
C
A
C
C
A
G
G
C
T
C
T
C
C
C
T
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C
T
G
C
C
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G
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G
G
A
G
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G
A
C
C
A
G
G
A
G
A
G
G
G
A
T
T
C
A
G
T
C
T
0.001957
0.015656
0.02544
0.005871
0.037182
0.027397
0.009785
0.027397
0.031311
0.048924
0.054795
0.009785
0.021526
0.021526
0.017613
0.052838
0.084149
0.07045
0.093933
0.023483
0.003914
0.009785
0.009785
0.043053
0.021526
0.029354
0.035225
0.076321
0.04501
0.003914
0.007828
0.033268
1
4,574
C
C
A
C
A
G
A
G
A
G
T
A
C
A
C
C
A
C
C
C
T
C
T
T
C
C
C
T
G
T
A
C
C
T
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G
T
C
A
C
C
A
G
G
G
T
C
C
C
C
A
T
T
G
T
C
T
C
C
C
C
G
A
G
G
G
0.011742
0.015656
0.031311
0.001957
0.035225
0.052838
0.011742
0.015656
0.033268
0.027397
0.088063
0.007828
0.005871
0.015656
0.021526
0.054795
0.048924
0.068493
0.123288
0.011742
0.009785
0.001957
0.015656
0.068493
0.019569
0.031311
0.009785
0.058708
0.054795
0.011742
0.007828
0.027397
1
4,575
G
T
C
A
C
C
A
G
G
G
T
C
C
C
C
A
T
T
G
T
C
T
C
C
C
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G
A
G
G
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C
C
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G
T
C
A
C
C
A
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C
C
A
A
G
C
C
C
C
G
A
G
G
C
C
C
T
C
G
T
T
G
0.009785
0.015656
0.027397
0.001957
0.033268
0.050881
0.011742
0.017613
0.035225
0.029354
0.086106
0.003914
0.009785
0.015656
0.019569
0.054795
0.056751
0.066536
0.119374
0.011742
0.009785
0.001957
0.011742
0.072407
0.017613
0.031311
0.013699
0.056751
0.054795
0.011742
0.007828
0.033268
1
4,576
G
G
C
C
T
G
G
A
G
G
C
C
C
C
A
G
G
A
T
C
A
C
A
G
C
T
G
A
G
T
C
T
C
C
C
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A
G
G
G
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C
A
G
G
C
A
G
G
A
A
T
C
A
G
A
G
G
A
G
T
C
G
A
0.013699
0.013699
0.02544
0.011742
0.019569
0.043053
0.017613
0.027397
0.027397
0.019569
0.07045
0.007828
0.017613
0.021526
0.02544
0.056751
0.046967
0.062622
0.133072
0.015656
0.009785
0.007828
0.007828
0.062622
0.017613
0.029354
0.029354
0.052838
0.050881
0.007828
0.007828
0.039139
1
4,577
G
G
G
G
T
C
C
C
T
C
C
T
G
G
C
C
G
G
G
G
C
G
G
C
C
A
T
C
T
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C
A
C
C
C
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G
G
A
T
G
G
T
G
A
C
A
T
T
A
G
G
T
T
C
A
T
T
G
A
C
T
C
A
G
T
0.009785
0.011742
0.019569
0.007828
0.027397
0.041096
0.015656
0.029354
0.027397
0.023483
0.080235
0.001957
0.021526
0.019569
0.011742
0.039139
0.066536
0.050881
0.103718
0.027397
0.009785
0.009785
0.011742
0.062622
0.023483
0.04501
0.019569
0.04501
0.072407
0.017613
0.003914
0.043053
1
4,578
T
G
G
T
C
C
A
G
G
T
G
G
C
C
C
C
A
G
G
G
G
T
C
C
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G
G
G
A
T
T
C
C
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C
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C
C
C
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G
G
G
G
G
G
C
C
T
G
C
C
A
G
A
C
C
C
T
A
C
C
T
0.015656
0.013699
0.023483
0.009785
0.027397
0.054795
0.005871
0.023483
0.043053
0.019569
0.080235
0.001957
0.009785
0.017613
0.02544
0.048924
0.054795
0.064579
0.11546
0.011742
0.005871
0.007828
0.019569
0.068493
0.017613
0.035225
0.023483
0.054795
0.048924
0.013699
0.003914
0.033268
1
4,579
G
G
G
G
T
C
C
T
G
G
G
A
T
T
C
C
T
T
C
T
C
T
C
C
C
T
G
G
G
G
G
G
C
C
T
G
C
C
A
G
A
C
C
C
T
A
C
C
A
G
A
A
A
A
A
T
G
G
G
G
C
A
A
G
A
A
0.015656
0.013699
0.021526
0.009785
0.02544
0.056751
0.005871
0.021526
0.037182
0.019569
0.084149
0.001957
0.009785
0.017613
0.023483
0.048924
0.056751
0.066536
0.117417
0.015656
0.005871
0.007828
0.019569
0.064579
0.017613
0.033268
0.023483
0.058708
0.050881
0.013699
0.003914
0.031311
1
4,580
G
A
G
A
G
A
T
G
G
G
T
C
A
G
C
C
A
G
G
C
C
C
T
A
G
T
G
G
A
G
A
G
C
G
G
G
T
G
A
G
G
G
G
C
T
G
G
G
A
A
C
A
G
C
A
T
G
T
A
G
G
G
G
C
A
T
0.017613
0.017613
0.019569
0.015656
0.017613
0.050881
0.003914
0.019569
0.039139
0.015656
0.084149
0.003914
0.013699
0.02544
0.019569
0.035225
0.062622
0.064579
0.125245
0.017613
0.003914
0.001957
0.015656
0.060665
0.02544
0.02544
0.031311
0.064579
0.050881
0.013699
0.005871
0.031311
1
4,581
C
C
C
T
C
A
C
C
C
G
C
T
C
T
C
C
A
C
T
A
G
G
G
C
C
T
G
G
C
T
G
A
C
C
C
A
T
C
T
C
T
C
C
T
C
G
A
G
G
G
C
C
T
G
T
C
T
G
A
C
C
C
G
G
G
A
0.015656
0.017613
0.017613
0.013699
0.017613
0.048924
0
0.019569
0.039139
0.015656
0.086106
0.001957
0.013699
0.02544
0.019569
0.031311
0.066536
0.064579
0.129159
0.021526
0.003914
0.001957
0.013699
0.062622
0.02544
0.027397
0.029354
0.066536
0.056751
0.011742
0.003914
0.031311
1
4,582
C
T
G
A
C
C
C
A
T
C
T
C
T
C
C
T
C
G
A
G
G
G
C
C
T
G
T
C
T
G
A
C
C
C
G
G
G
A
A
C
C
C
A
A
C
A
A
C
A
C
C
A
G
G
A
G
C
A
C
C
G
G
G
C
A
T
0.017613
0.017613
0.019569
0.013699
0.017613
0.046967
0
0.017613
0.037182
0.015656
0.09002
0.001957
0.013699
0.02544
0.021526
0.027397
0.064579
0.060665
0.133072
0.019569
0.005871
0.001957
0.011742
0.064579
0.027397
0.027397
0.029354
0.066536
0.058708
0.009785
0.003914
0.031311
1
4,583
C
A
G
G
A
G
G
C
C
C
A
G
G
G
G
A
G
C
C
C
G
G
G
A
C
C
C
C
G
A
C
T
C
C
T
G
G
G
T
C
A
C
C
C
T
T
T
G
A
G
G
A
A
A
A
G
A
G
G
C
A
T
C
G
G
A
0.033268
0.027397
0.023483
0.013699
0.033268
0.046967
0.003914
0.017613
0.031311
0.023483
0.078278
0.007828
0.015656
0.033268
0.023483
0.02544
0.066536
0.043053
0.09589
0.021526
0.011742
0.001957
0.005871
0.054795
0.035225
0.037182
0.027397
0.041096
0.056751
0.011742
0.005871
0.04501
1
4,584
C
A
G
G
G
G
A
G
C
C
C
G
G
G
A
C
C
C
C
G
A
C
T
C
C
T
G
G
G
T
C
A
C
C
C
T
T
T
G
A
G
G
A
A
A
A
G
A
G
G
C
A
T
C
G
G
A
T
C
A
A
G
C
T
C
T
0.033268
0.027397
0.02544
0.017613
0.033268
0.046967
0.003914
0.017613
0.033268
0.023483
0.074364
0.007828
0.015656
0.033268
0.027397
0.02544
0.066536
0.046967
0.093933
0.021526
0.007828
0.001957
0.005871
0.050881
0.037182
0.037182
0.027397
0.039139
0.054795
0.011742
0.005871
0.04501
1
4,585
C
A
G
G
G
A
C
C
C
T
T
C
T
G
G
G
T
A
C
A
C
A
T
A
C
C
T
T
G
A
A
A
C
C
T
T
T
G
G
G
T
C
C
T
G
G
A
G
C
C
C
C
T
T
T
C
T
G
A
C
C
C
T
A
A
A
0.023483
0.021526
0.023483
0.015656
0.037182
0.04501
0.005871
0.021526
0.039139
0.029354
0.068493
0.011742
0.015656
0.043053
0.021526
0.027397
0.068493
0.046967
0.080235
0.013699
0.007828
0.003914
0.011742
0.056751
0.035225
0.04501
0.023483
0.033268
0.050881
0.015656
0.003914
0.052838
1
4,586
C
A
G
G
G
A
C
C
C
T
T
C
T
G
G
G
T
A
C
A
C
A
T
A
C
C
T
T
G
A
A
A
C
C
T
T
T
G
G
G
T
C
C
T
G
G
A
G
C
C
C
C
T
T
T
C
T
G
A
C
C
C
T
A
A
T
0.023483
0.021526
0.023483
0.015656
0.037182
0.04501
0.005871
0.021526
0.039139
0.029354
0.068493
0.011742
0.015656
0.043053
0.021526
0.027397
0.068493
0.046967
0.080235
0.013699
0.007828
0.003914
0.011742
0.056751
0.035225
0.04501
0.023483
0.033268
0.050881
0.015656
0.003914
0.052838
1
4,587
A
C
A
T
A
C
C
T
T
G
A
A
A
C
C
T
T
T
G
G
G
T
C
C
T
G
G
A
G
C
C
C
C
T
T
T
C
T
G
A
C
C
C
T
A
A
G
A
A
A
A
C
C
C
A
G
C
A
A
A
C
A
G
C
A
T
0.023483
0.021526
0.023483
0.011742
0.041096
0.041096
0.005871
0.021526
0.039139
0.029354
0.072407
0.011742
0.015656
0.043053
0.019569
0.031311
0.07045
0.046967
0.078278
0.013699
0.007828
0.003914
0.011742
0.056751
0.033268
0.041096
0.02544
0.039139
0.048924
0.015656
0.003914
0.050881
1
4,588
C
C
C
T
T
G
C
C
T
A
G
G
C
C
C
C
G
G
A
C
T
C
A
C
A
T
C
T
T
C
C
C
C
A
G
G
G
T
C
T
C
C
G
G
G
C
T
C
C
C
C
T
G
C
A
C
G
G
C
C
A
G
C
T
T
G
0.007828
0.009785
0.027397
0.003914
0.046967
0.02544
0.001957
0.023483
0.046967
0.035225
0.066536
0.005871
0.017613
0.031311
0.017613
0.052838
0.072407
0.050881
0.074364
0.029354
0.011742
0.011742
0.005871
0.064579
0.017613
0.035225
0.037182
0.084149
0.037182
0.001957
0.005871
0.039139
1
4,589
A
G
G
C
C
C
C
G
G
A
C
T
C
A
C
A
T
C
T
T
C
C
C
C
A
G
G
G
T
C
T
C
C
G
G
G
C
T
C
C
C
C
T
G
C
A
C
G
G
C
C
A
G
C
T
T
C
A
C
C
C
T
G
C
A
T
0.009785
0.009785
0.027397
0.003914
0.04501
0.02544
0.001957
0.02544
0.04501
0.035225
0.066536
0.007828
0.017613
0.033268
0.017613
0.048924
0.07045
0.048924
0.072407
0.029354
0.011742
0.011742
0.009785
0.064579
0.019569
0.035225
0.035225
0.082192
0.037182
0.003914
0.005871
0.041096
1
4,590
G
G
C
C
C
C
C
G
T
G
G
G
G
C
C
A
G
G
T
T
C
T
C
C
T
T
T
A
G
G
T
C
C
G
A
C
A
G
G
G
C
C
A
G
G
C
A
G
A
C
C
T
G
G
T
G
A
C
C
C
C
T
A
T
G
T
0.017613
0.013699
0.017613
0.005871
0.033268
0.04501
0.003914
0.023483
0.033268
0.039139
0.07045
0.007828
0.007828
0.017613
0.011742
0.064579
0.074364
0.068493
0.119374
0.011742
0.009785
0.005871
0.011742
0.062622
0.023483
0.02544
0.037182
0.056751
0.046967
0.001957
0.001957
0.029354
1
4,591
G
T
T
C
T
C
C
T
T
T
A
G
G
T
C
C
G
A
C
A
G
G
G
C
C
A
G
G
C
A
G
A
C
C
T
G
G
T
G
A
C
C
C
C
T
A
T
G
G
C
A
G
A
G
C
A
G
C
G
T
G
A
G
G
A
G
0.017613
0.011742
0.019569
0.005871
0.035225
0.043053
0.003914
0.021526
0.033268
0.041096
0.074364
0.007828
0.007828
0.017613
0.011742
0.062622
0.076321
0.064579
0.109589
0.011742
0.013699
0.005871
0.011742
0.062622
0.023483
0.027397
0.039139
0.058708
0.046967
0.001957
0.001957
0.029354
1
4,592
G
G
C
T
C
C
C
T
C
T
G
T
C
T
C
C
A
T
C
T
T
T
T
C
C
A
C
T
G
G
C
A
C
C
A
T
C
T
C
G
A
C
C
T
G
G
G
G
C
T
C
C
C
G
G
C
T
T
C
C
C
T
G
T
C
T
0.015656
0.017613
0.021526
0.003914
0.046967
0.048924
0.009785
0.019569
0.037182
0.029354
0.07045
0.007828
0.009785
0.021526
0.017613
0.052838
0.076321
0.062622
0.097847
0.013699
0.015656
0.003914
0.009785
0.050881
0.023483
0.050881
0.023483
0.052838
0.046967
0.003914
0.001957
0.035225
1
4,593
G
T
C
T
C
C
A
T
C
T
T
T
T
C
C
A
C
T
G
G
C
A
C
C
A
T
C
T
C
G
A
C
C
T
G
G
G
G
C
T
C
C
C
G
G
C
T
T
C
C
C
T
G
T
C
T
C
C
C
C
C
T
G
A
G
G
0.015656
0.017613
0.019569
0.003914
0.046967
0.046967
0.009785
0.021526
0.037182
0.029354
0.07045
0.007828
0.009785
0.021526
0.017613
0.054795
0.074364
0.062622
0.097847
0.013699
0.015656
0.003914
0.009785
0.054795
0.021526
0.050881
0.023483
0.052838
0.046967
0.003914
0.001957
0.035225
1
4,594
C
T
T
T
T
C
C
A
C
T
G
G
C
A
C
C
A
T
C
T
C
G
A
C
C
T
G
G
G
G
C
T
C
C
C
G
G
C
T
T
C
C
C
T
G
T
C
T
C
C
C
C
C
T
G
A
G
A
G
G
G
A
A
G
A
G
0.013699
0.017613
0.019569
0.003914
0.048924
0.048924
0.009785
0.021526
0.035225
0.029354
0.07045
0.007828
0.005871
0.021526
0.017613
0.058708
0.074364
0.064579
0.097847
0.013699
0.015656
0.003914
0.009785
0.054795
0.021526
0.048924
0.023483
0.052838
0.046967
0.003914
0.001957
0.035225
1
4,595
T
T
T
T
C
C
A
C
T
G
G
C
A
C
C
A
T
C
T
C
G
A
C
C
T
G
G
G
G
C
T
C
C
C
G
G
C
T
T
C
C
C
T
G
T
C
T
C
C
C
C
C
T
G
A
G
A
G
G
G
A
A
G
A
G
T
0.013699
0.017613
0.019569
0.003914
0.048924
0.048924
0.009785
0.021526
0.035225
0.029354
0.072407
0.007828
0.005871
0.021526
0.017613
0.058708
0.074364
0.064579
0.097847
0.013699
0.015656
0.003914
0.009785
0.054795
0.021526
0.048924
0.023483
0.052838
0.046967
0.003914
0.001957
0.033268
1
4,596
A
G
C
T
C
T
T
C
C
C
T
C
T
C
A
G
G
G
G
G
A
G
A
C
A
G
G
G
A
A
G
C
C
G
G
G
A
G
C
C
C
C
A
G
G
T
C
G
A
G
A
T
G
G
T
G
C
C
A
G
T
G
G
A
A
T
0.013699
0.017613
0.019569
0.003914
0.048924
0.046967
0.009785
0.021526
0.035225
0.029354
0.072407
0.007828
0.005871
0.021526
0.017613
0.056751
0.074364
0.064579
0.097847
0.013699
0.015656
0.003914
0.009785
0.054795
0.021526
0.048924
0.023483
0.056751
0.046967
0.003914
0.001957
0.033268
1
4,597
T
G
G
C
A
C
C
A
T
C
T
C
G
A
C
C
T
G
G
G
G
C
T
C
C
C
G
G
C
T
T
C
C
C
T
G
T
C
T
C
C
C
C
C
T
G
A
G
A
G
G
G
A
A
G
A
G
C
T
C
T
G
T
C
A
T
0.013699
0.017613
0.021526
0.003914
0.046967
0.046967
0.009785
0.021526
0.035225
0.029354
0.074364
0.007828
0.005871
0.021526
0.017613
0.056751
0.074364
0.062622
0.097847
0.013699
0.015656
0.003914
0.009785
0.054795
0.023483
0.046967
0.023483
0.056751
0.04501
0.003914
0.001957
0.035225
1
4,598
C
T
C
G
A
C
C
T
G
G
G
G
C
T
C
C
C
G
G
C
T
T
C
C
C
T
G
T
C
T
C
C
C
C
C
T
G
A
G
A
G
G
G
A
A
G
A
G
C
T
C
T
G
T
C
A
G
G
G
C
T
G
C
C
T
T
0.013699
0.017613
0.021526
0.003914
0.046967
0.046967
0.009785
0.021526
0.035225
0.029354
0.072407
0.007828
0.005871
0.021526
0.017613
0.056751
0.072407
0.062622
0.097847
0.017613
0.015656
0.003914
0.009785
0.054795
0.023483
0.046967
0.023483
0.056751
0.04501
0.003914
0.001957
0.035225
1
4,599
T
C
G
A
C
C
T
G
G
G
G
C
T
C
C
C
G
G
C
T
T
C
C
C
T
G
T
C
T
C
C
C
C
C
T
G
A
G
A
G
G
G
A
A
G
A
G
C
T
C
T
G
T
C
A
G
G
G
C
T
G
C
C
T
G
T
0.013699
0.017613
0.021526
0.003914
0.046967
0.048924
0.009785
0.021526
0.035225
0.029354
0.072407
0.007828
0.005871
0.021526
0.017613
0.056751
0.072407
0.062622
0.097847
0.015656
0.015656
0.003914
0.009785
0.054795
0.023483
0.046967
0.023483
0.056751
0.04501
0.003914
0.001957
0.035225
1
4,600
A
A
C
T
C
A
C
C
A
C
T
T
G
T
C
C
A
G
G
C
A
A
A
C
C
T
G
G
A
G
A
C
C
C
C
T
G
T
G
G
A
C
C
C
T
G
A
C
G
G
A
G
A
A
C
A
A
G
T
C
G
G
A
T
G
T
0.013699
0.019569
0.02544
0.003914
0.048924
0.043053
0.005871
0.027397
0.033268
0.027397
0.07045
0.007828
0.007828
0.023483
0.019569
0.050881
0.072407
0.062622
0.099804
0.013699
0.013699
0.001957
0.011742
0.052838
0.027397
0.048924
0.017613
0.050881
0.052838
0.005871
0.001957
0.037182
1
4,601
A
C
T
C
A
C
C
A
C
T
T
G
T
C
C
A
G
G
C
A
A
A
C
C
T
G
G
A
G
A
C
C
C
C
T
G
T
G
G
A
C
C
C
T
G
A
C
G
G
A
G
A
A
C
A
A
G
T
C
G
G
A
T
G
T
G
0.013699
0.019569
0.02544
0.003914
0.048924
0.043053
0.005871
0.027397
0.033268
0.029354
0.07045
0.007828
0.007828
0.023483
0.019569
0.050881
0.07045
0.062622
0.099804
0.013699
0.013699
0.001957
0.011742
0.052838
0.027397
0.048924
0.017613
0.050881
0.052838
0.005871
0.001957
0.037182
1
4,602
A
C
T
C
A
C
C
A
C
T
T
G
T
C
C
A
G
G
C
A
A
A
C
C
T
G
G
A
G
A
C
C
C
C
T
G
T
G
G
A
C
C
C
T
G
A
C
G
G
A
G
A
A
C
A
A
G
T
C
G
G
A
T
G
T
T
0.013699
0.019569
0.02544
0.003914
0.048924
0.043053
0.005871
0.027397
0.033268
0.029354
0.07045
0.007828
0.007828
0.023483
0.019569
0.050881
0.07045
0.062622
0.099804
0.013699
0.013699
0.001957
0.011742
0.052838
0.027397
0.048924
0.017613
0.050881
0.052838
0.005871
0.001957
0.037182
1
4,603
C
C
T
G
A
C
T
G
G
A
C
C
T
A
C
T
G
G
A
G
C
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C
C
C
T
T
C
A
G
G
C
C
T
T
G
T
G
G
T
G
A
T
0.009785
0.023483
0.021526
0.003914
0.043053
0.043053
0.011742
0.027397
0.033268
0.029354
0.078278
0.001957
0.007828
0.02544
0.027397
0.043053
0.072407
0.060665
0.086106
0.011742
0.007828
0.003914
0.013699
0.060665
0.019569
0.052838
0.023483
0.048924
0.058708
0.005871
0.001957
0.041096
1
4,604
G
G
G
G
T
C
C
A
G
G
A
A
G
T
C
C
C
A
C
A
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C
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G
G
A
G
G
A
A
G
A
G
A
A
A
G
T
T
C
A
G
G
G
0.009785
0.023483
0.023483
0.003914
0.04501
0.043053
0.011742
0.027397
0.027397
0.029354
0.078278
0.001957
0.007828
0.029354
0.029354
0.04501
0.068493
0.062622
0.082192
0.011742
0.007828
0.003914
0.013699
0.056751
0.019569
0.052838
0.023483
0.050881
0.060665
0.005871
0.001957
0.041096
1
4,605
C
T
C
T
C
C
C
C
G
G
T
C
T
C
C
T
T
T
G
A
T
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T
G
T
C
G
T
G
C
C
C
T
G
A
G
C
C
C
C
C
A
G
0.009785
0.011742
0.029354
0.007828
0.041096
0.048924
0.007828
0.029354
0.039139
0.019569
0.07045
0.009785
0.009785
0.027397
0.021526
0.060665
0.062622
0.056751
0.09002
0.017613
0.005871
0
0.021526
0.046967
0.017613
0.04501
0.048924
0.048924
0.048924
0.009785
0.009785
0.02544
1
4,606
G
G
G
T
C
C
G
G
G
G
G
G
C
C
C
A
G
G
G
G
T
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C
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T
C
T
G
C
C
C
T
G
C
A
G
G
A
A
A
C
A
A
G
T
0.017613
0.017613
0.023483
0.011742
0.033268
0.039139
0.007828
0.013699
0.048924
0.02544
0.072407
0.013699
0.023483
0.029354
0.015656
0.04501
0.064579
0.064579
0.113503
0.007828
0.003914
0.003914
0.017613
0.054795
0.029354
0.027397
0.02544
0.054795
0.050881
0.003914
0.007828
0.031311
1
4,607
G
G
G
G
C
C
C
A
G
G
G
G
T
T
C
C
A
G
G
G
A
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C
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C
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G
C
A
G
G
A
A
A
C
A
A
G
A
A
A
A
T
G
G
G
T
0.017613
0.017613
0.023483
0.011742
0.033268
0.041096
0.007828
0.013699
0.048924
0.02544
0.072407
0.013699
0.021526
0.027397
0.015656
0.046967
0.062622
0.064579
0.117417
0.007828
0.003914
0.003914
0.017613
0.054795
0.029354
0.027397
0.02544
0.054795
0.050881
0.003914
0.007828
0.029354
1
4,608
G
G
G
T
T
C
C
A
G
G
G
A
G
T
C
C
A
G
G
A
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A
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A
A
A
A
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G
G
G
G
T
G
G
C
A
G
C
C
A
0.017613
0.017613
0.023483
0.011742
0.029354
0.039139
0.007828
0.013699
0.046967
0.027397
0.072407
0.013699
0.021526
0.027397
0.015656
0.04501
0.066536
0.066536
0.123288
0.007828
0.003914
0.003914
0.015656
0.054795
0.029354
0.02544
0.02544
0.056751
0.050881
0.001957
0.007828
0.029354
1
4,609
G
G
T
T
C
C
A
G
G
G
A
G
T
C
C
A
G
G
A
G
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G
A
A
A
A
T
G
G
G
G
T
G
G
C
A
G
C
C
C
A
0.017613
0.017613
0.023483
0.011742
0.029354
0.039139
0.007828
0.013699
0.046967
0.027397
0.072407
0.013699
0.021526
0.027397
0.013699
0.04501
0.066536
0.066536
0.123288
0.007828
0.003914
0.003914
0.015656
0.054795
0.029354
0.02544
0.027397
0.056751
0.050881
0.001957
0.007828
0.029354
1
4,610
A
G
C
C
T
G
C
C
C
C
A
C
G
A
A
G
C
C
C
A
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C
T
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C
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T
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C
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C
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C
C
C
C
G
T
T
C
T
C
0.017613
0.013699
0.029354
0.013699
0.015656
0.037182
0.007828
0.011742
0.033268
0.033268
0.076321
0.009785
0.009785
0.017613
0.015656
0.037182
0.064579
0.074364
0.142857
0.023483
0.003914
0.003914
0.013699
0.048924
0.035225
0.017613
0.027397
0.080235
0.056751
0.003914
0.005871
0.017613
1
4,611
C
C
C
A
T
C
G
C
A
G
C
C
C
A
C
C
T
G
T
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C
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G
T
T
C
T
C
C
C
T
G
A
A
A
T
G
C
A
A
A
T
A
T
0.015656
0.013699
0.029354
0.009785
0.015656
0.039139
0.007828
0.011742
0.033268
0.033268
0.078278
0.009785
0.009785
0.017613
0.015656
0.039139
0.064579
0.076321
0.144814
0.023483
0.003914
0.003914
0.011742
0.048924
0.031311
0.017613
0.027397
0.084149
0.054795
0.003914
0.005871
0.017613
1
4,612
G
C
C
C
A
C
C
T
G
T
T
C
T
C
C
A
C
G
T
T
C
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T
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G
A
A
A
T
G
C
A
A
A
T
A
G
C
G
G
G
T
G
A
G
T
0.015656
0.011742
0.029354
0.009785
0.015656
0.037182
0.007828
0.011742
0.033268
0.033268
0.080235
0.007828
0.009785
0.015656
0.015656
0.039139
0.066536
0.076321
0.146771
0.023483
0.003914
0.003914
0.011742
0.050881
0.031311
0.017613
0.027397
0.086106
0.054795
0.003914
0.003914
0.017613
1
4,613
G
C
C
C
T
C
A
C
C
C
G
C
T
A
T
T
T
G
C
A
T
T
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A
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G
A
G
A
A
C
G
T
G
G
A
G
A
A
C
A
G
G
T
G
T
0.015656
0.011742
0.029354
0.009785
0.013699
0.039139
0.007828
0.011742
0.035225
0.033268
0.080235
0.007828
0.009785
0.015656
0.015656
0.037182
0.066536
0.076321
0.146771
0.023483
0.003914
0.003914
0.011742
0.050881
0.031311
0.019569
0.02544
0.086106
0.054795
0.003914
0.003914
0.017613
1
4,614
G
T
T
C
T
C
C
A
C
G
T
T
C
T
C
C
T
T
T
C
T
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T
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A
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C
A
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A
T
A
G
C
G
G
G
T
G
A
G
G
G
C
C
A
A
G
C
A
0.015656
0.011742
0.029354
0.009785
0.011742
0.039139
0.009785
0.009785
0.035225
0.033268
0.080235
0.007828
0.009785
0.015656
0.015656
0.035225
0.066536
0.078278
0.146771
0.023483
0.003914
0.003914
0.009785
0.052838
0.031311
0.019569
0.02544
0.086106
0.056751
0.003914
0.003914
0.017613
1
4,615
G
T
T
C
T
C
C
A
C
G
T
T
C
T
C
C
T
T
T
C
T
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G
T
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A
A
A
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C
A
A
A
T
A
G
C
G
G
G
T
G
A
G
G
G
C
C
A
A
G
C
T
0.015656
0.011742
0.029354
0.009785
0.011742
0.039139
0.009785
0.009785
0.035225
0.033268
0.080235
0.007828
0.009785
0.015656
0.015656
0.035225
0.066536
0.078278
0.146771
0.023483
0.003914
0.003914
0.009785
0.052838
0.031311
0.019569
0.02544
0.086106
0.056751
0.003914
0.003914
0.017613
1
4,616
C
A
C
T
C
T
C
C
T
G
G
C
C
A
G
C
C
C
C
C
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C
C
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C
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C
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C
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C
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G
G
C
C
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C
C
T
G
C
C
T
C
T
C
C
C
A
C
A
C
C
C
C
C
A
C
0.015656
0.013699
0.02544
0.009785
0.015656
0.031311
0.013699
0.007828
0.041096
0.039139
0.074364
0.003914
0.005871
0.015656
0.011742
0.035225
0.07045
0.076321
0.135029
0.027397
0.007828
0.009785
0.003914
0.062622
0.037182
0.011742
0.031311
0.09002
0.056751
0.007828
0
0.011742
1
4,617
C
T
C
C
T
G
G
C
C
A
G
C
C
C
C
C
A
G
C
C
T
C
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C
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G
G
C
C
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C
C
T
C
T
C
C
C
A
C
A
C
C
C
C
C
A
G
C
C
C
T
0.015656
0.015656
0.02544
0.009785
0.017613
0.031311
0.013699
0.007828
0.041096
0.039139
0.074364
0.003914
0.005871
0.015656
0.013699
0.037182
0.068493
0.074364
0.133072
0.027397
0.007828
0.009785
0.003914
0.062622
0.037182
0.011742
0.031311
0.088063
0.056751
0.007828
0
0.011742
1
4,618
C
A
G
C
C
C
C
C
A
G
C
C
T
C
A
C
C
C
T
C
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G
G
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C
A
C
C
C
C
C
A
G
C
C
C
T
G
C
C
T
G
G
G
T
0.015656
0.013699
0.02544
0.009785
0.017613
0.031311
0.013699
0.009785
0.041096
0.039139
0.072407
0.003914
0.005871
0.015656
0.013699
0.039139
0.07045
0.074364
0.131115
0.027397
0.007828
0.009785
0.003914
0.064579
0.035225
0.011742
0.031311
0.088063
0.054795
0.007828
0
0.013699
1
4,619
T
C
T
C
T
C
C
T
G
G
C
C
T
T
C
C
T
G
C
C
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G
G
A
G
C
C
C
G
G
G
A
A
T
A
C
C
A
G
G
C
T
0.015656
0.013699
0.027397
0.009785
0.017613
0.033268
0.013699
0.009785
0.043053
0.043053
0.068493
0.003914
0.005871
0.015656
0.013699
0.043053
0.068493
0.072407
0.127202
0.027397
0.007828
0.009785
0.003914
0.064579
0.037182
0.009785
0.033268
0.086106
0.050881
0.007828
0
0.015656
1
4,620
C
C
T
C
T
C
C
C
A
C
A
C
C
C
C
C
A
G
C
C
C
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C
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A
A
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G
C
T
T
T
C
C
A
G
G
C
T
C
C
C
C
G
G
C
A
T
0.013699
0.013699
0.029354
0.009785
0.019569
0.033268
0.013699
0.009785
0.039139
0.043053
0.07045
0.003914
0.003914
0.013699
0.015656
0.043053
0.066536
0.074364
0.135029
0.027397
0.007828
0.009785
0.003914
0.062622
0.035225
0.009785
0.029354
0.09002
0.048924
0.007828
0
0.015656
1
4,621
C
T
C
T
C
C
C
A
C
A
C
C
C
C
C
A
G
C
C
C
T
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C
T
T
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C
C
A
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G
C
T
C
C
C
C
G
G
C
A
A
A
0.013699
0.013699
0.029354
0.009785
0.019569
0.033268
0.013699
0.009785
0.039139
0.043053
0.07045
0.003914
0.003914
0.013699
0.015656
0.043053
0.066536
0.074364
0.135029
0.027397
0.007828
0.009785
0.003914
0.062622
0.035225
0.009785
0.029354
0.09002
0.048924
0.007828
0
0.015656
1
4,622
C
T
C
T
C
C
C
A
C
A
C
C
C
C
C
A
G
C
C
C
T
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A
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C
T
T
T
C
C
A
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G
C
T
C
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G
G
C
A
A
G
0.013699
0.013699
0.029354
0.009785
0.019569
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0.07045
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0.135029
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0.003914
0.062622
0.035225
0.009785
0.029354
0.09002
0.048924
0.007828
0
0.015656
1
4,623
C
T
C
T
C
C
C
A
C
A
C
C
C
C
C
A
G
C
C
C
T
G
C
C
T
G
G
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A
G
C
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A
A
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G
C
T
T
T
C
C
A
G
G
C
T
C
C
C
C
G
G
C
A
A
T
0.013699
0.013699
0.029354
0.009785
0.019569
0.033268
0.013699
0.009785
0.039139
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0.062622
0.035225
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0.029354
0.09002
0.048924
0.007828
0
0.015656
1
4,624
C
A
C
C
C
C
C
A
G
C
C
C
T
G
C
C
T
G
G
G
A
G
C
C
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A
A
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C
T
T
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C
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G
G
C
T
C
C
C
C
G
G
C
A
A
G
G
C
C
G
G
A
A
T
0.009785
0.013699
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0.007828
0.017613
0.033268
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0.009785
0.037182
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0.009785
0.029354
0.091977
0.048924
0.007828
0
0.017613
1
4,625
A
C
C
C
C
C
A
G
C
C
C
T
G
C
C
T
G
G
G
A
G
C
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A
A
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G
C
T
C
C
C
C
G
G
C
A
A
G
G
C
C
G
G
A
A
G
T
0.009785
0.013699
0.027397
0.007828
0.017613
0.033268
0.013699
0.011742
0.037182
0.043053
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0.064579
0.035225
0.009785
0.029354
0.091977
0.048924
0.007828
0
0.017613
1
4,626
C
C
C
T
G
C
C
T
G
G
G
A
G
C
C
C
G
G
G
A
A
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A
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G
G
C
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T
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C
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C
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C
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C
A
A
G
G
C
C
G
G
A
A
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G
C
C
C
G
G
G
G
A
0.009785
0.013699
0.029354
0.007828
0.017613
0.031311
0.013699
0.011742
0.037182
0.043053
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0.015656
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0.07045
0.136986
0.027397
0.009785
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0.003914
0.064579
0.035225
0.011742
0.027397
0.09002
0.050881
0.007828
0
0.017613
1
4,627
C
C
C
T
G
C
C
T
G
G
G
A
G
C
C
C
G
G
G
A
A
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C
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G
C
A
A
G
G
C
C
G
G
A
A
G
G
C
C
C
G
G
G
G
T
0.009785
0.013699
0.029354
0.007828
0.017613
0.031311
0.013699
0.011742
0.037182
0.043053
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0.07045
0.136986
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0.009785
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0.003914
0.064579
0.035225
0.011742
0.027397
0.09002
0.050881
0.007828
0
0.017613
1
4,628
C
C
T
G
C
C
T
G
G
G
A
G
C
C
C
G
G
G
A
A
T
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C
T
T
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C
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C
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C
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C
A
A
G
G
C
C
G
G
A
A
G
G
C
C
C
G
G
G
G
G
T
0.009785
0.013699
0.029354
0.007828
0.017613
0.031311
0.013699
0.011742
0.037182
0.043053
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0.011742
0.015656
0.041096
0.066536
0.072407
0.136986
0.027397
0.009785
0.011742
0.003914
0.064579
0.035225
0.011742
0.027397
0.09002
0.050881
0.007828
0
0.017613
1
4,629
G
A
G
C
C
C
G
G
G
A
A
T
A
C
C
A
G
G
C
T
T
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C
C
A
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G
C
T
C
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G
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C
C
G
G
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A
G
G
C
C
C
G
G
G
G
G
G
G
C
C
C
C
T
C
T
T
0.009785
0.013699
0.029354
0.007828
0.017613
0.031311
0.013699
0.011742
0.037182
0.039139
0.076321
0.003914
0.003914
0.011742
0.015656
0.039139
0.064579
0.07045
0.136986
0.027397
0.013699
0.011742
0.003914
0.066536
0.035225
0.013699
0.02544
0.091977
0.050881
0.007828
0
0.017613
1
4,630
C
T
T
T
C
C
A
G
G
C
T
C
C
C
C
G
G
C
A
A
G
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C
C
G
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A
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C
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C
C
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T
C
T
C
C
C
C
A
A
G
G
G
C
C
A
G
A
C
C
A
G
T
0.009785
0.015656
0.029354
0.007828
0.015656
0.031311
0.017613
0.011742
0.035225
0.035225
0.074364
0.003914
0.003914
0.011742
0.015656
0.041096
0.058708
0.068493
0.138943
0.031311
0.015656
0.013699
0.003914
0.064579
0.037182
0.011742
0.027397
0.093933
0.048924
0.007828
0
0.017613
1
4,631
G
G
C
C
C
C
T
C
T
C
C
C
C
A
A
G
G
G
C
C
A
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C
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G
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G
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C
C
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G
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G
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C
C
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G
G
G
T
C
T
C
C
A
C
G
G
T
C
G
C
C
C
T
T
C
T
0.009785
0.011742
0.029354
0.007828
0.013699
0.033268
0.013699
0.011742
0.039139
0.039139
0.076321
0.003914
0.007828
0.011742
0.015656
0.037182
0.060665
0.066536
0.133072
0.031311
0.013699
0.011742
0.005871
0.07045
0.035225
0.013699
0.02544
0.088063
0.052838
0.009785
0
0.019569
1
4,632
C
C
C
A
A
G
G
G
C
C
A
G
A
C
C
A
G
G
T
G
G
C
C
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G
A
G
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C
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C
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C
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G
T
C
G
C
C
C
T
T
C
A
G
C
C
C
G
C
G
T
T
T
0.007828
0.011742
0.027397
0.007828
0.013699
0.033268
0.013699
0.011742
0.037182
0.039139
0.076321
0.003914
0.007828
0.011742
0.015656
0.037182
0.062622
0.066536
0.136986
0.033268
0.013699
0.013699
0.005871
0.068493
0.031311
0.013699
0.027397
0.088063
0.052838
0.009785
0
0.019569
1
4,633
G
C
T
T
T
C
C
T
G
G
A
G
A
A
C
G
C
G
G
G
C
T
G
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C
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G
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C
C
C
T
G
G
C
C
C
T
C
A
G
G
G
G
C
C
A
C
C
T
G
G
T
G
0.007828
0.009785
0.027397
0.007828
0.013699
0.033268
0.011742
0.011742
0.035225
0.039139
0.078278
0.003914
0.009785
0.013699
0.015656
0.037182
0.066536
0.066536
0.133072
0.031311
0.013699
0.013699
0.005871
0.066536
0.029354
0.013699
0.031311
0.091977
0.048924
0.009785
0
0.021526
1
4,634
G
T
G
G
C
C
C
C
T
G
A
G
G
G
C
C
A
G
G
G
T
C
T
C
C
A
C
G
G
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C
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C
C
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C
A
G
C
C
C
G
C
G
T
T
C
T
C
C
A
G
G
A
A
A
G
C
C
G
A
T
G
G
0.007828
0.009785
0.027397
0.007828
0.015656
0.033268
0.011742
0.011742
0.035225
0.039139
0.078278
0.003914
0.009785
0.013699
0.015656
0.037182
0.064579
0.066536
0.133072
0.031311
0.013699
0.013699
0.005871
0.066536
0.027397
0.015656
0.031311
0.091977
0.050881
0.009785
0
0.019569
1
4,635
A
G
G
G
C
C
A
G
G
G
T
C
T
C
C
A
C
G
G
T
C
G
C
C
C
T
T
C
A
G
C
C
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C
G
T
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C
T
C
C
A
G
G
A
A
A
G
C
C
G
A
T
G
G
G
G
C
C
C
T
G
C
A
T
0.003914
0.009785
0.029354
0.003914
0.015656
0.035225
0.011742
0.011742
0.037182
0.041096
0.080235
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0.009785
0.011742
0.015656
0.037182
0.066536
0.066536
0.133072
0.031311
0.013699
0.013699
0.003914
0.068493
0.027397
0.017613
0.029354
0.091977
0.050881
0.009785
0
0.019569
1
4,636
C
A
G
A
G
C
T
C
T
C
A
T
C
C
C
A
G
G
T
C
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C
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A
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C
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C
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C
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C
A
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T
G
C
C
T
G
A
G
G
G
A
C
A
G
C
A
A
G
A
G
G
T
T
0.009785
0.015656
0.033268
0.003914
0.027397
0.035225
0.015656
0.017613
0.035225
0.04501
0.064579
0.001957
0.015656
0.017613
0.019569
0.046967
0.068493
0.054795
0.101761
0.023483
0.017613
0.021526
0.013699
0.046967
0.031311
0.023483
0.046967
0.07045
0.039139
0.009785
0.001957
0.023483
1
4,637
G
A
C
C
T
C
T
T
G
C
T
G
T
C
C
C
T
C
A
G
G
C
A
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C
T
G
C
C
C
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G
C
G
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G
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G
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T
C
G
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G
G
A
G
A
C
C
T
G
G
G
A
T
G
A
G
A
G
C
T
C
T
T
0.009785
0.015656
0.033268
0.003914
0.027397
0.035225
0.015656
0.017613
0.035225
0.04501
0.064579
0.001957
0.015656
0.017613
0.019569
0.046967
0.068493
0.054795
0.103718
0.023483
0.017613
0.021526
0.013699
0.04501
0.031311
0.023483
0.046967
0.07045
0.039139
0.009785
0.001957
0.023483
1
4,638
C
C
T
G
G
G
C
A
T
G
T
G
G
A
A
A
A
G
G
T
G
G
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G
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C
C
T
C
A
C
C
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C
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C
C
C
C
T
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G
G
A
T
C
C
A
G
T
C
T
C
C
C
C
A
C
G
G
T
C
A
C
0.027397
0.019569
0.031311
0.009785
0.035225
0.041096
0.009785
0.011742
0.027397
0.031311
0.066536
0.005871
0.015656
0.050881
0.029354
0.052838
0.050881
0.074364
0.091977
0.011742
0.001957
0.007828
0.013699
0.041096
0.029354
0.019569
0.041096
0.064579
0.046967
0.005871
0.001957
0.031311
1
4,639
A
G
G
T
G
G
G
G
G
C
C
T
C
A
C
C
T
G
C
T
C
C
C
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G
G
A
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C
C
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C
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C
G
G
T
C
A
C
C
C
T
G
A
A
A
A
C
A
A
G
A
A
T
T
0.027397
0.017613
0.031311
0.011742
0.035225
0.041096
0.009785
0.013699
0.02544
0.029354
0.066536
0.003914
0.015656
0.050881
0.029354
0.052838
0.048924
0.074364
0.093933
0.011742
0.001957
0.007828
0.011742
0.043053
0.029354
0.023483
0.039139
0.064579
0.046967
0.005871
0.001957
0.033268
1
4,640
G
T
C
T
C
A
C
C
G
G
T
A
A
T
C
C
A
G
G
G
G
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A
C
C
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A
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C
C
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G
G
C
C
C
T
G
T
T
C
T
C
C
A
C
G
G
A
G
G
C
C
T
G
G
A
T
0.037182
0.021526
0.033268
0.007828
0.035225
0.037182
0.011742
0.017613
0.046967
0.015656
0.068493
0.009785
0.033268
0.027397
0.021526
0.035225
0.056751
0.060665
0.097847
0.011742
0.007828
0.007828
0.015656
0.043053
0.027397
0.031311
0.019569
0.050881
0.054795
0.015656
0.013699
0.02544
1
4,641
G
G
G
A
C
C
A
G
A
G
G
G
G
C
C
A
G
G
G
A
G
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C
C
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G
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C
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A
A
G
C
C
C
C
T
G
G
A
A
A
A
A
G
T
C
T
T
T
0.039139
0.021526
0.039139
0.007828
0.029354
0.039139
0.007828
0.017613
0.046967
0.015656
0.07045
0.009785
0.033268
0.023483
0.02544
0.029354
0.056751
0.062622
0.103718
0.011742
0.007828
0.007828
0.013699
0.041096
0.029354
0.031311
0.019569
0.050881
0.054795
0.013699
0.013699
0.02544
1
4,642
T
C
T
C
C
C
C
T
C
A
C
T
T
A
C
G
T
C
T
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T
G
C
C
T
G
C
A
G
C
A
C
C
C
T
G
A
G
G
A
G
A
G
A
C
T
C
T
0.013699
0.019569
0.043053
0.003914
0.023483
0.043053
0.007828
0.023483
0.052838
0.033268
0.07045
0.003914
0.013699
0.033268
0.035225
0.019569
0.060665
0.050881
0.103718
0.005871
0.009785
0.003914
0.021526
0.054795
0.023483
0.050881
0.033268
0.043053
0.039139
0.009785
0.007828
0.041096
1
4,643
C
T
C
T
C
C
C
T
G
G
G
T
C
C
C
C
A
G
C
T
T
T
G
C
C
T
G
C
A
G
C
A
C
C
C
T
G
A
G
G
A
G
A
G
A
C
T
C
A
A
A
G
T
C
A
G
T
T
C
A
T
C
A
T
G
T
0.013699
0.019569
0.041096
0.005871
0.02544
0.043053
0.007828
0.023483
0.052838
0.031311
0.066536
0.003914
0.013699
0.035225
0.033268
0.021526
0.058708
0.050881
0.103718
0.007828
0.011742
0.003914
0.021526
0.054795
0.02544
0.048924
0.031311
0.046967
0.037182
0.009785
0.007828
0.041096
1
4,644
G
G
G
C
C
C
A
G
C
G
G
C
T
C
C
T
G
G
T
T
T
C
C
C
A
T
C
C
A
G
T
C
C
G
C
T
C
C
G
G
C
C
A
T
C
C
A
G
C
C
C
A
G
G
G
G
G
A
C
C
C
C
G
G
T
T
0.013699
0.015656
0.029354
0.005871
0.029354
0.056751
0.003914
0.015656
0.043053
0.02544
0.074364
0.005871
0.015656
0.031311
0.021526
0.037182
0.062622
0.066536
0.103718
0.017613
0.007828
0.005871
0.015656
0.050881
0.019569
0.04501
0.021526
0.060665
0.04501
0.007828
0.009785
0.035225
1
4,645
G
T
T
T
C
C
C
A
T
C
C
A
G
T
C
C
G
C
T
C
C
G
G
C
C
A
T
C
C
A
G
C
C
C
A
G
G
G
G
G
A
C
C
C
C
G
G
T
C
A
C
C
C
T
G
T
G
G
A
A
A
A
T
A
G
T
0.015656
0.017613
0.031311
0.007828
0.029354
0.054795
0.003914
0.015656
0.043053
0.023483
0.074364
0.005871
0.015656
0.029354
0.023483
0.037182
0.060665
0.064579
0.101761
0.019569
0.009785
0.005871
0.015656
0.050881
0.023483
0.041096
0.023483
0.058708
0.04501
0.007828
0.009785
0.033268
1
4,646
C
C
A
G
T
C
C
G
C
T
C
C
G
G
C
C
A
T
C
C
A
G
C
C
C
A
G
G
G
G
G
A
C
C
C
C
G
G
T
C
A
C
C
C
T
G
T
G
G
A
A
A
A
T
A
G
A
G
T
G
G
T
A
A
G
A
0.015656
0.017613
0.031311
0.007828
0.029354
0.054795
0.003914
0.013699
0.041096
0.023483
0.076321
0.005871
0.017613
0.029354
0.023483
0.037182
0.062622
0.064579
0.101761
0.019569
0.009785
0.005871
0.011742
0.050881
0.023483
0.039139
0.023483
0.060665
0.04501
0.007828
0.009785
0.035225
1