row_idx
int64
f_0_ref__32
string
f_1_ref__31
string
f_2_ref__30
string
f_3_ref__29
string
f_4_ref__28
string
f_5_ref__27
string
f_6_ref__26
string
f_7_ref__25
string
f_8_ref__24
string
f_9_ref__23
string
f_10_ref__22
string
f_11_ref__21
string
f_12_ref__20
string
f_13_ref__19
string
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string
f_15_ref__17
string
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string
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string
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string
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string
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string
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string
f_22_ref__10
string
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string
f_24_ref__8
string
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string
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string
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string
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string
f_29_ref__3
string
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string
f_31_ref__1
string
f_32_ref_0
string
f_33_ref__1
string
f_34_ref__2
string
f_35_ref__3
string
f_36_ref__4
string
f_37_ref__5
string
f_38_ref__6
string
f_39_ref__7
string
f_40_ref__8
string
f_41_ref__9
string
f_42_ref__10
string
f_43_ref__11
string
f_44_ref__12
string
f_45_ref__13
string
f_46_ref__14
string
f_47_ref__15
string
f_48_ref__16
string
f_49_ref__17
string
f_50_ref__18
string
f_51_ref__19
string
f_52_ref__20
string
f_53_ref__21
string
f_54_ref__22
string
f_55_ref__23
string
f_56_ref__24
string
f_57_ref__25
string
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string
f_59_ref__27
string
f_60_ref__28
string
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string
f_62_ref__30
string
f_63_ref__31
string
f_64_ref__32
string
f_65_alt
string
f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
int64
7,991
A
G
C
A
C
C
A
A
C
G
G
G
A
C
C
A
A
T
A
T
T
G
C
C
A
G
G
G
T
A
A
C
C
G
C
G
C
T
C
T
C
C
C
T
A
C
C
A
A
A
G
G
C
A
A
A
A
T
G
A
A
G
C
T
T
T
0.043053
0.033268
0.039139
0.02544
0.037182
0.050881
0.011742
0.031311
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0.054795
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0.011742
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0.027397
0.037182
0.02544
0.033268
0.021526
0.019569
0.039139
1
7,992
C
A
G
G
A
C
C
C
A
C
G
G
G
G
C
C
A
T
G
A
G
G
A
C
C
A
G
G
T
G
C
A
C
C
T
G
C
A
G
C
A
C
C
A
A
C
G
G
G
A
C
C
A
A
T
A
T
T
G
C
C
A
G
G
G
T
0.043053
0.031311
0.037182
0.02544
0.037182
0.056751
0.009785
0.02544
0.02544
0.035225
0.048924
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0.043053
0.050881
0.050881
0.060665
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0.011742
0.007828
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0.033268
0.029354
0.039139
0.029354
0.035225
0.017613
0.017613
0.033268
1
7,993
G
T
T
T
G
C
C
A
G
C
A
G
G
A
C
C
C
A
C
G
G
G
G
C
C
A
T
G
A
G
G
A
C
C
A
G
G
T
G
C
A
C
C
T
G
C
A
G
C
A
C
C
A
A
C
G
G
G
A
C
C
A
A
T
A
T
0.043053
0.029354
0.037182
0.02544
0.039139
0.056751
0.009785
0.02544
0.02544
0.031311
0.048924
0.011742
0.015656
0.029354
0.041096
0.050881
0.050881
0.060665
0.056751
0.011742
0.007828
0.009785
0.019569
0.023483
0.033268
0.029354
0.039139
0.029354
0.035225
0.021526
0.017613
0.033268
1
7,994
A
A
C
T
T
A
C
A
G
T
T
T
C
A
C
C
A
C
G
G
T
T
T
C
C
A
T
G
T
T
T
G
C
C
A
G
C
A
G
G
A
C
C
C
A
C
G
G
G
G
C
C
A
T
G
A
G
G
A
C
C
A
G
G
T
T
0.046967
0.033268
0.041096
0.027397
0.043053
0.054795
0.009785
0.027397
0.027397
0.027397
0.043053
0.009785
0.017613
0.031311
0.04501
0.050881
0.046967
0.058708
0.052838
0.011742
0.007828
0.009785
0.017613
0.019569
0.037182
0.029354
0.041096
0.023483
0.035225
0.019569
0.019569
0.033268
1
7,995
A
A
C
T
T
A
C
A
G
T
T
T
C
A
C
C
A
C
G
G
T
T
T
C
C
A
T
G
T
T
T
G
C
C
A
G
C
A
G
G
A
C
C
C
A
C
G
G
G
G
C
C
A
T
G
A
G
G
A
C
C
A
G
G
T
A
0.046967
0.033268
0.041096
0.027397
0.043053
0.054795
0.009785
0.027397
0.027397
0.027397
0.043053
0.009785
0.017613
0.031311
0.04501
0.050881
0.046967
0.058708
0.052838
0.011742
0.007828
0.009785
0.017613
0.019569
0.037182
0.029354
0.041096
0.023483
0.035225
0.019569
0.019569
0.033268
1
7,996
A
G
C
A
C
C
A
G
C
A
G
G
A
C
C
A
A
C
A
G
G
A
C
C
A
G
A
A
G
G
A
C
C
C
T
G
T
G
A
A
A
T
G
A
A
A
A
A
G
A
A
A
A
A
C
A
C
A
A
C
T
T
A
G
C
T
0.066536
0.035225
0.035225
0.043053
0.043053
0.037182
0.007828
0.029354
0.037182
0.033268
0.033268
0.033268
0.019569
0.029354
0.04501
0.037182
0.04501
0.048924
0.037182
0.007828
0.001957
0.005871
0.02544
0.027397
0.033268
0.023483
0.035225
0.019569
0.035225
0.021526
0.037182
0.029354
1
7,997
T
T
T
C
A
C
C
G
G
G
C
T
C
T
C
C
C
T
T
A
T
C
G
C
C
A
C
G
A
A
T
G
C
C
T
T
G
T
G
G
G
C
C
C
T
A
T
A
A
A
G
A
A
A
C
A
G
A
A
G
G
A
T
G
G
T
0.060665
0.02544
0.048924
0.048924
0.037182
0.021526
0.005871
0.029354
0.041096
0.041096
0.041096
0.048924
0.033268
0.029354
0.031311
0.027397
0.039139
0.037182
0.017613
0.005871
0.009785
0.005871
0.029354
0.035225
0.031311
0.009785
0.02544
0.033268
0.029354
0.031311
0.058708
0.029354
1
7,998
T
G
G
G
C
C
C
C
T
T
T
T
C
A
C
C
G
G
G
C
T
C
T
C
C
C
T
T
A
T
C
G
C
C
A
C
G
A
A
T
G
C
C
T
T
G
T
G
G
G
C
C
C
T
A
T
A
A
A
G
A
A
A
C
A
G
0.062622
0.02544
0.048924
0.04501
0.037182
0.023483
0.005871
0.029354
0.039139
0.041096
0.041096
0.050881
0.031311
0.031311
0.031311
0.027397
0.039139
0.039139
0.017613
0.005871
0.009785
0.005871
0.029354
0.033268
0.031311
0.009785
0.02544
0.033268
0.029354
0.033268
0.058708
0.027397
1
7,999
T
A
A
G
C
C
A
G
G
A
A
G
A
C
C
T
C
T
G
G
G
C
C
C
C
T
T
T
T
C
A
C
C
G
G
G
C
T
C
T
C
C
C
T
T
A
T
C
G
C
C
A
C
G
A
A
T
G
C
C
T
T
G
T
G
G
0.062622
0.02544
0.048924
0.04501
0.037182
0.02544
0.005871
0.027397
0.039139
0.037182
0.04501
0.046967
0.033268
0.035225
0.027397
0.029354
0.039139
0.039139
0.017613
0.005871
0.009785
0.005871
0.027397
0.033268
0.033268
0.009785
0.02544
0.033268
0.031311
0.031311
0.056751
0.029354
1
8,000
A
C
T
T
A
C
A
G
C
G
A
T
A
C
C
A
G
G
C
A
G
A
C
C
T
T
G
C
A
A
T
C
C
A
T
T
G
T
G
T
C
C
C
T
T
T
A
A
G
C
C
A
G
G
A
A
G
A
C
C
T
C
T
G
G
T
0.058708
0.023483
0.04501
0.043053
0.035225
0.027397
0.005871
0.027397
0.043053
0.035225
0.046967
0.048924
0.031311
0.035225
0.023483
0.029354
0.041096
0.041096
0.019569
0.005871
0.009785
0.005871
0.031311
0.035225
0.035225
0.011742
0.023483
0.033268
0.033268
0.031311
0.052838
0.029354
1
8,001
T
A
C
T
T
A
C
A
G
C
G
A
T
A
C
C
A
G
G
C
A
G
A
C
C
T
T
G
C
A
A
T
C
C
A
T
T
G
T
G
T
C
C
C
T
T
T
A
A
G
C
C
A
G
G
A
A
G
A
C
C
T
C
T
G
T
0.058708
0.023483
0.04501
0.043053
0.035225
0.027397
0.005871
0.027397
0.041096
0.035225
0.046967
0.048924
0.031311
0.037182
0.023483
0.029354
0.041096
0.041096
0.019569
0.005871
0.009785
0.005871
0.031311
0.035225
0.035225
0.011742
0.023483
0.033268
0.033268
0.031311
0.052838
0.029354
1
8,002
C
T
A
C
A
G
T
T
T
A
C
T
T
A
C
A
G
C
G
A
T
A
C
C
A
G
G
C
A
G
A
C
C
T
T
G
C
A
A
T
C
C
A
T
T
G
T
G
T
C
C
C
T
T
T
A
A
G
C
C
A
G
G
A
A
T
0.058708
0.023483
0.04501
0.043053
0.037182
0.027397
0.005871
0.02544
0.041096
0.033268
0.048924
0.048924
0.031311
0.037182
0.02544
0.027397
0.041096
0.039139
0.019569
0.005871
0.009785
0.005871
0.027397
0.035225
0.037182
0.013699
0.023483
0.031311
0.035225
0.031311
0.052838
0.031311
1
8,003
G
C
T
A
C
A
G
T
T
T
A
C
T
T
A
C
A
G
C
G
A
T
A
C
C
A
G
G
C
A
G
A
C
C
T
T
G
C
A
A
T
C
C
A
T
T
G
T
G
T
C
C
C
T
T
T
A
A
G
C
C
A
G
G
A
G
0.056751
0.02544
0.04501
0.043053
0.037182
0.027397
0.005871
0.02544
0.041096
0.033268
0.048924
0.048924
0.031311
0.037182
0.02544
0.027397
0.041096
0.039139
0.019569
0.005871
0.009785
0.005871
0.027397
0.035225
0.037182
0.013699
0.023483
0.031311
0.035225
0.031311
0.052838
0.031311
1
8,004
G
G
A
G
C
C
A
G
G
A
G
C
A
C
C
T
T
G
A
T
C
A
C
C
A
T
G
G
T
G
A
C
C
C
T
T
T
A
A
A
G
A
C
A
G
A
A
G
A
G
G
A
A
A
A
T
C
A
C
A
C
T
T
T
C
G
0.084149
0.015656
0.037182
0.048924
0.035225
0.037182
0.001957
0.02544
0.041096
0.035225
0.043053
0.02544
0.015656
0.037182
0.027397
0.035225
0.050881
0.048924
0.031311
0.005871
0.003914
0.003914
0.021526
0.035225
0.041096
0.035225
0.027397
0.019569
0.043053
0.013699
0.033268
0.039139
1
8,005
A
G
G
A
C
C
A
G
C
A
G
G
A
C
C
C
A
C
G
G
A
G
C
C
A
G
G
A
G
C
A
C
C
T
T
G
A
T
C
A
C
C
A
T
G
G
T
G
A
C
C
C
T
T
T
A
A
A
G
A
C
A
G
A
A
T
0.084149
0.011742
0.035225
0.048924
0.031311
0.035225
0.001957
0.02544
0.041096
0.035225
0.046967
0.02544
0.015656
0.035225
0.023483
0.035225
0.052838
0.048924
0.035225
0.005871
0.007828
0.003914
0.021526
0.039139
0.041096
0.035225
0.027397
0.023483
0.041096
0.011742
0.031311
0.041096
1
8,006
T
C
T
T
G
A
G
T
C
C
A
C
C
T
A
C
C
C
T
A
G
G
A
C
C
A
G
C
A
G
G
A
C
C
C
A
C
G
G
A
G
C
C
A
G
G
A
G
C
A
C
C
T
T
G
A
T
C
A
C
C
A
T
G
G
T
0.078278
0.009785
0.037182
0.046967
0.031311
0.037182
0.001957
0.02544
0.041096
0.037182
0.050881
0.021526
0.015656
0.033268
0.02544
0.035225
0.056751
0.048924
0.033268
0.005871
0.007828
0.003914
0.021526
0.039139
0.041096
0.035225
0.029354
0.027397
0.041096
0.013699
0.02544
0.041096
1
8,007
T
G
C
G
A
C
C
A
T
C
T
T
T
T
C
C
A
G
C
A
G
G
G
C
C
A
G
A
A
G
G
A
C
C
A
G
C
A
G
G
G
C
C
C
T
A
A
G
G
A
A
G
A
C
A
G
A
C
A
C
C
A
G
G
T
T
0.060665
0.015656
0.046967
0.031311
0.035225
0.041096
0.003914
0.019569
0.046967
0.037182
0.052838
0.029354
0.023483
0.033268
0.029354
0.031311
0.056751
0.050881
0.037182
0.003914
0.007828
0.003914
0.021526
0.031311
0.035225
0.039139
0.027397
0.029354
0.037182
0.013699
0.029354
0.037182
1
8,008
C
A
G
G
T
C
C
A
A
C
T
G
T
A
C
C
A
G
G
A
T
G
T
C
C
A
G
T
G
C
G
A
C
C
A
T
C
T
T
T
T
C
C
A
G
C
A
G
G
G
C
C
A
G
A
A
G
G
A
C
C
A
G
C
A
A
0.041096
0.015656
0.048924
0.029354
0.031311
0.041096
0.003914
0.023483
0.043053
0.037182
0.056751
0.02544
0.02544
0.029354
0.029354
0.035225
0.060665
0.054795
0.04501
0.003914
0.007828
0.003914
0.021526
0.029354
0.035225
0.037182
0.033268
0.031311
0.041096
0.013699
0.029354
0.035225
1
8,009
C
A
G
G
G
C
C
T
T
G
G
T
G
A
C
C
C
T
G
A
G
G
G
C
C
T
C
G
A
A
T
G
C
C
A
G
C
A
G
G
T
C
C
A
A
C
T
G
T
A
C
C
A
G
G
A
T
G
T
C
C
A
G
T
G
T
0.043053
0.019569
0.04501
0.035225
0.029354
0.041096
0.005871
0.023483
0.035225
0.037182
0.054795
0.033268
0.02544
0.031311
0.031311
0.031311
0.056751
0.054795
0.04501
0.003914
0.009785
0.003914
0.021526
0.027397
0.031311
0.035225
0.031311
0.033268
0.039139
0.013699
0.035225
0.035225
1
8,010
T
A
T
T
A
T
T
T
C
C
C
C
A
A
A
T
C
A
T
A
C
T
T
A
C
A
G
C
A
G
G
G
C
C
T
T
G
G
T
G
A
C
C
C
T
G
A
G
G
G
C
C
T
C
G
A
A
T
G
C
C
A
G
C
A
T
0.043053
0.021526
0.04501
0.035225
0.033268
0.033268
0.007828
0.02544
0.037182
0.037182
0.050881
0.033268
0.023483
0.033268
0.029354
0.029354
0.058708
0.050881
0.043053
0.005871
0.009785
0.003914
0.021526
0.027397
0.037182
0.033268
0.031311
0.033268
0.039139
0.015656
0.035225
0.035225
1
8,011
G
A
G
G
T
C
C
A
G
G
A
G
G
G
C
C
A
G
G
G
G
G
A
C
C
A
G
G
G
G
G
G
C
C
C
T
G
C
A
A
A
G
G
T
G
A
A
A
G
T
G
A
G
A
T
A
G
G
A
G
A
G
G
C
T
T
0.041096
0.027397
0.043053
0.027397
0.027397
0.031311
0.007828
0.037182
0.048924
0.037182
0.039139
0.037182
0.021526
0.035225
0.035225
0.031311
0.048924
0.04501
0.043053
0.005871
0.007828
0.005871
0.017613
0.052838
0.031311
0.029354
0.029354
0.029354
0.029354
0.013699
0.033268
0.048924
1
8,012
T
A
C
A
C
C
T
G
G
A
G
G
T
C
C
A
G
G
A
G
G
G
C
C
A
G
G
G
G
G
A
C
C
A
G
G
G
G
G
G
C
C
C
T
G
C
A
A
A
G
G
T
G
A
A
A
G
T
G
A
G
A
T
A
G
G
0.039139
0.02544
0.043053
0.027397
0.02544
0.033268
0.007828
0.037182
0.048924
0.037182
0.041096
0.037182
0.021526
0.035225
0.031311
0.033268
0.048924
0.046967
0.043053
0.005871
0.007828
0.005871
0.019569
0.052838
0.031311
0.029354
0.029354
0.029354
0.029354
0.015656
0.033268
0.046967
1
8,013
A
C
C
A
C
C
G
C
T
T
A
C
A
C
C
T
G
G
A
G
G
T
C
C
A
G
G
A
G
G
G
C
C
A
G
G
G
G
G
A
C
C
A
G
G
G
G
G
G
C
C
C
T
G
C
A
A
A
G
G
T
G
A
A
A
T
0.037182
0.02544
0.043053
0.02544
0.027397
0.033268
0.007828
0.035225
0.050881
0.037182
0.041096
0.037182
0.023483
0.035225
0.033268
0.033268
0.048924
0.04501
0.041096
0.005871
0.007828
0.005871
0.019569
0.052838
0.031311
0.031311
0.029354
0.029354
0.031311
0.015656
0.029354
0.048924
1
8,014
C
A
C
C
A
C
C
G
C
T
T
A
C
A
C
C
T
G
G
A
G
G
T
C
C
A
G
G
A
G
G
G
C
C
A
G
G
G
G
G
A
C
C
A
G
G
G
G
G
G
C
C
C
T
G
C
A
A
A
G
G
T
G
A
A
T
0.037182
0.023483
0.043053
0.02544
0.027397
0.033268
0.007828
0.035225
0.050881
0.037182
0.041096
0.037182
0.023483
0.035225
0.033268
0.033268
0.048924
0.046967
0.041096
0.005871
0.007828
0.005871
0.019569
0.052838
0.031311
0.031311
0.029354
0.029354
0.031311
0.015656
0.029354
0.048924
1
8,015
C
A
C
C
A
C
C
G
C
T
T
A
C
A
C
C
T
G
G
A
G
G
T
C
C
A
G
G
A
G
G
G
C
C
A
G
G
G
G
G
A
C
C
A
G
G
G
G
G
G
C
C
C
T
G
C
A
A
A
G
G
T
G
A
A
G
0.037182
0.023483
0.043053
0.02544
0.027397
0.033268
0.007828
0.035225
0.050881
0.037182
0.041096
0.037182
0.023483
0.035225
0.033268
0.033268
0.048924
0.046967
0.041096
0.005871
0.007828
0.005871
0.019569
0.052838
0.031311
0.031311
0.029354
0.029354
0.031311
0.015656
0.029354
0.048924
1
8,016
G
T
C
A
T
A
A
C
C
A
C
C
A
C
C
G
C
T
T
A
C
A
C
C
T
G
G
A
G
G
T
C
C
A
G
G
A
G
G
G
C
C
A
G
G
G
G
G
A
C
C
A
G
G
G
G
G
G
C
C
C
T
G
C
A
T
0.037182
0.023483
0.043053
0.02544
0.027397
0.035225
0.007828
0.035225
0.054795
0.035225
0.041096
0.037182
0.023483
0.033268
0.033268
0.033268
0.052838
0.046967
0.037182
0.005871
0.007828
0.005871
0.017613
0.052838
0.031311
0.035225
0.029354
0.027397
0.031311
0.015656
0.027397
0.048924
1
8,017
G
T
A
A
C
C
A
A
A
G
T
C
A
T
A
A
C
C
A
C
C
A
C
C
G
C
T
T
A
C
A
C
C
T
G
G
A
G
G
T
C
C
A
G
G
A
G
G
G
C
C
A
G
G
G
G
G
A
C
C
A
G
G
G
G
T
0.035225
0.023483
0.04501
0.021526
0.027397
0.037182
0.007828
0.037182
0.054795
0.035225
0.043053
0.031311
0.023483
0.033268
0.031311
0.033268
0.054795
0.046967
0.039139
0.005871
0.007828
0.005871
0.017613
0.052838
0.031311
0.037182
0.029354
0.027397
0.031311
0.015656
0.027397
0.048924
1
8,018
G
T
A
A
C
C
A
A
A
G
T
C
A
T
A
A
C
C
A
C
C
A
C
C
G
C
T
T
A
C
A
C
C
T
G
G
A
G
G
T
C
C
A
G
G
A
G
G
G
C
C
A
G
G
G
G
G
A
C
C
A
G
G
G
G
A
0.035225
0.023483
0.04501
0.021526
0.027397
0.037182
0.007828
0.037182
0.054795
0.035225
0.043053
0.031311
0.023483
0.033268
0.031311
0.033268
0.054795
0.046967
0.039139
0.005871
0.007828
0.005871
0.017613
0.052838
0.031311
0.037182
0.029354
0.027397
0.031311
0.015656
0.027397
0.048924
1
8,019
G
G
G
T
C
T
G
A
G
A
G
A
A
G
G
T
G
C
T
G
A
G
C
G
A
G
G
C
T
G
G
T
C
A
G
C
C
C
T
G
T
A
G
A
A
G
T
C
T
C
C
A
T
C
G
T
A
A
C
C
A
A
A
G
T
T
0.04501
0.02544
0.04501
0.023483
0.027397
0.037182
0.007828
0.041096
0.052838
0.037182
0.041096
0.019569
0.017613
0.033268
0.033268
0.037182
0.052838
0.043053
0.037182
0.005871
0.007828
0.005871
0.017613
0.056751
0.035225
0.035225
0.027397
0.02544
0.02544
0.015656
0.02544
0.058708
1
8,020
T
G
G
G
T
C
T
G
A
G
A
G
A
A
G
G
T
G
C
T
G
A
G
C
G
A
G
G
C
T
G
G
T
C
A
G
C
C
C
T
G
T
A
G
A
A
G
T
C
T
C
C
A
T
C
G
T
A
A
C
C
A
A
A
G
C
0.04501
0.02544
0.04501
0.023483
0.027397
0.037182
0.007828
0.041096
0.052838
0.037182
0.041096
0.019569
0.017613
0.033268
0.033268
0.037182
0.052838
0.043053
0.035225
0.005871
0.007828
0.005871
0.017613
0.056751
0.035225
0.035225
0.029354
0.02544
0.02544
0.015656
0.02544
0.058708
1
8,021
A
A
G
G
A
T
G
C
A
C
T
A
T
G
G
A
T
G
C
T
A
T
C
A
A
A
G
T
A
T
A
C
T
G
T
G
A
T
T
T
C
T
C
T
A
C
T
G
G
C
G
A
A
A
C
C
T
G
T
A
T
C
C
G
G
A
0.078278
0.035225
0.035225
0.052838
0.033268
0.027397
0.003914
0.029354
0.048924
0.021526
0.04501
0.041096
0.037182
0.033268
0.031311
0.015656
0.04501
0.037182
0.027397
0.003914
0.001957
0.001957
0.031311
0.033268
0.041096
0.017613
0.017613
0.017613
0.041096
0.02544
0.050881
0.037182
1
8,022
T
C
T
C
C
T
C
A
T
C
C
A
T
G
T
A
T
G
C
A
A
T
G
C
T
G
T
T
C
T
T
G
C
A
G
T
G
G
T
A
G
G
T
G
A
T
G
T
T
C
T
G
A
G
A
G
G
C
A
T
A
G
T
T
G
A
0.078278
0.037182
0.058708
0.027397
0.031311
0.017613
0
0.046967
0.056751
0.02544
0.039139
0.021526
0.021526
0.041096
0.033268
0.015656
0.043053
0.033268
0.043053
0
0
0.003914
0.033268
0.033268
0.056751
0.015656
0.029354
0.023483
0.031311
0.027397
0.035225
0.039139
1
8,023
T
A
T
T
T
A
A
G
G
C
A
A
T
G
A
G
A
T
A
A
A
G
A
T
C
T
G
C
T
T
A
C
C
C
C
T
C
C
T
T
C
A
G
G
T
C
A
T
T
A
A
T
G
G
G
A
A
G
T
G
G
C
A
C
C
A
0.078278
0.023483
0.050881
0.058708
0.027397
0.017613
0.007828
0.027397
0.058708
0.011742
0.027397
0.064579
0.043053
0.048924
0.029354
0.027397
0.02544
0.033268
0.017613
0.005871
0.003914
0.009785
0.033268
0.013699
0.046967
0.013699
0.031311
0.033268
0.015656
0.015656
0.058708
0.039139
1
8,024
C
G
C
A
G
T
G
A
A
A
A
A
T
G
T
G
T
G
G
C
A
G
C
C
A
G
A
G
C
G
C
C
T
G
A
A
C
G
C
C
A
T
A
A
A
C
A
T
C
A
C
A
T
C
G
G
C
C
C
T
A
G
A
C
A
G
0.082192
0.029354
0.052838
0.062622
0.031311
0.015656
0.007828
0.027397
0.052838
0.011742
0.027397
0.060665
0.035225
0.04501
0.037182
0.023483
0.029354
0.033268
0.017613
0.005871
0.005871
0.011742
0.02544
0.011742
0.048924
0.013699
0.035225
0.035225
0.015656
0.015656
0.056751
0.035225
1
8,025
G
C
T
T
C
C
C
C
A
C
A
T
T
T
T
C
A
G
C
T
G
T
T
G
G
G
G
A
C
C
C
A
T
A
T
A
G
G
A
C
T
C
C
A
T
C
A
C
T
A
T
A
T
G
G
T
G
T
C
C
T
T
T
G
G
C
0.099804
0.043053
0.027397
0.060665
0.086106
0.02544
0
0.02544
0.035225
0.017613
0.013699
0.062622
0.02544
0.048924
0.039139
0.048924
0.023483
0.041096
0.019569
0.001957
0.007828
0.001957
0.027397
0.013699
0.033268
0.015656
0.009785
0.009785
0.021526
0.029354
0.060665
0.023483
1
8,026
C
A
T
A
T
A
G
G
A
C
T
C
C
A
T
C
A
C
T
A
T
A
T
G
G
T
G
T
C
C
T
T
T
G
G
A
T
A
T
A
T
C
G
A
A
G
C
C
A
T
C
C
A
G
G
T
C
G
G
T
C
T
G
G
G
C
0.097847
0.041096
0.023483
0.066536
0.084149
0.027397
0.003914
0.023483
0.035225
0.013699
0.015656
0.054795
0.027397
0.048924
0.037182
0.052838
0.021526
0.043053
0.021526
0.001957
0.007828
0.001957
0.029354
0.013699
0.031311
0.015656
0.011742
0.011742
0.021526
0.029354
0.062622
0.021526
1
8,027
C
A
A
A
T
G
T
G
C
A
G
G
G
T
G
C
C
A
A
A
G
C
A
T
G
C
T
T
T
C
T
G
C
G
G
G
A
C
A
T
T
C
C
T
T
T
C
T
C
G
G
C
C
A
T
C
T
A
C
T
T
T
C
C
G
T
0.084149
0.033268
0.046967
0.035225
0.043053
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0.052838
0.009785
0.050881
0.019569
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0.015656
0.017613
0.035225
1
8,028
A
A
T
G
A
A
G
A
G
A
G
C
T
T
C
A
A
A
A
G
G
T
A
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T
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A
G
C
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C
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A
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T
T
T
C
T
G
C
T
G
C
A
A
G
T
G
G
G
A
C
C
T
0.076321
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0.050881
0.054795
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0.027397
0.005871
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0.046967
0.021526
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0.019569
0.04501
0.023483
0.041096
0.015656
0.017613
0.021526
0.054795
0.037182
1
8,029
C
T
G
C
T
G
T
G
T
A
T
C
C
T
A
T
C
G
A
T
C
T
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T
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A
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A
A
C
G
A
T
C
A
A
C
T
G
G
C
T
C
T
T
T
T
G
0.093933
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0.027397
0.027397
0.048924
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0.037182
0.019569
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0.021526
0.009785
0
0.009785
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0.02544
0.04501
0.017613
0.021526
0.009785
0.019569
0.029354
0.058708
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1
8,030
T
C
G
T
T
G
G
T
T
C
T
G
C
A
T
T
C
G
A
G
T
T
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A
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A
G
C
A
G
T
G
G
C
T
C
C
A
A
C
A
G
C
T
A
T
0.097847
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0.029354
0.048924
0.033268
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0.007828
0
0.009785
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0.023483
0.04501
0.017613
0.021526
0.011742
0.017613
0.027397
0.064579
0.041096
1
8,031
T
T
C
A
T
G
A
T
C
T
T
C
T
T
G
A
T
C
T
T
G
G
A
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A
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T
T
C
A
C
C
T
G
A
G
T
T
G
G
G
G
A
A
C
A
A
0.019569
0.019569
0.02544
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0.015656
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0.033268
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0.02544
0.029354
0.076321
0.043053
0.011742
0.005871
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1
8,032
T
A
G
T
G
C
A
T
G
G
C
A
G
C
G
C
C
G
T
A
T
T
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A
A
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C
C
C
A
G
C
G
A
G
G
C
G
G
C
C
A
G
C
T
C
G
G
C
G
G
0.043053
0.029354
0.029354
0.023483
0.023483
0.043053
0.015656
0.031311
0.041096
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0.023483
0.04501
0.023483
0.021526
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0.041096
1
8,033
T
A
G
T
T
C
G
A
T
C
T
G
C
G
C
G
G
A
G
A
A
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C
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G
A
A
G
C
C
T
C
T
C
A
C
T
C
T
C
C
T
C
C
G
0.138943
0.048924
0.043053
0.043053
0.052838
0.013699
0
0.027397
0.037182
0.035225
0.039139
0.046967
0.015656
0.023483
0.056751
0.021526
0.023483
0.023483
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0.005871
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0.031311
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0.019569
0.021526
0.031311
0.017613
0.041096
0.029354
1
8,034
A
A
T
A
T
A
T
G
T
A
A
C
C
C
T
G
C
G
T
A
A
G
T
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C
A
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C
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A
T
C
C
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C
C
A
G
A
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A
A
G
A
T
C
A
C
C
A
C
G
C
T
A
T
C
T
G
T
G
T
0.091977
0.02544
0.056751
0.068493
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0.017613
0.003914
0.04501
0.046967
0.015656
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0.023483
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0.027397
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0.021526
0.050881
0.011742
0.007828
0.003914
0.02544
0.041096
0.064579
0.04501
1
8,035
G
G
C
G
G
T
A
G
T
T
G
A
C
C
C
G
C
T
G
T
T
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G
G
A
A
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G
C
A
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C
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A
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A
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T
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A
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G
A
A
A
T
A
T
C
C
G
T
A
T
T
T
G
T
G
G
C
T
0.068493
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0.035225
0.050881
0.04501
0.027397
0.007828
0.027397
0.04501
0.029354
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0.048924
0.015656
0.041096
0.013699
0.02544
0.019569
0.021526
0.048924
1
8,036
C
T
C
C
A
T
A
G
A
A
A
G
C
T
T
A
T
A
G
C
T
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A
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C
A
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C
A
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G
G
G
C
G
C
T
G
T
T
T
G
G
C
A
G
T
G
A
T
G
C
0.064579
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0.064579
0.037182
0.031311
0.007828
0.023483
0.046967
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0.043053
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0.043053
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0.009785
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0.02544
0.048924
0.013699
0.043053
0.019569
0.029354
0.021526
0.027397
0.039139
1
8,037
A
G
A
G
T
G
G
C
C
T
G
C
A
C
A
A
G
C
A
G
C
A
C
A
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G
A
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A
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C
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C
T
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G
T
G
G
A
G
C
T
G
T
G
T
C
T
C
A
C
C
G
T
C
C
C
T
G
T
G
T
0.015656
0.019569
0.035225
0.011742
0.052838
0.033268
0.011742
0.023483
0.039139
0.054795
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0.007828
0.013699
0.033268
0.027397
0.050881
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0.017613
0.048924
0.023483
0.033268
0.058708
0.035225
0.039139
0.017613
0.015656
0.033268
1
8,038
T
C
A
A
G
C
T
G
G
C
G
A
C
A
A
A
G
G
G
C
A
G
G
G
C
G
C
T
G
G
G
C
C
G
C
A
G
G
T
C
C
T
T
A
A
T
G
A
C
A
G
C
A
G
A
C
A
T
G
A
A
G
G
C
G
T
0.078278
0.013699
0.041096
0.041096
0.033268
0.023483
0.011742
0.027397
0.029354
0.043053
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0.02544
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0.023483
0.037182
0.037182
0.054795
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0.013699
0.017613
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0.019569
0.029354
0.033268
0.029354
0.043053
0.027397
0.011742
0.029354
0.04501
1
8,039
G
G
A
C
C
T
G
C
G
G
C
C
C
A
G
C
G
C
C
C
T
G
C
C
C
T
T
T
G
T
C
G
C
C
A
G
C
T
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G
A
T
C
C
G
C
C
A
C
T
A
T
A
C
G
A
T
G
G
T
G
G
C
A
G
T
0.078278
0.015656
0.04501
0.037182
0.031311
0.02544
0.011742
0.031311
0.02544
0.046967
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0.023483
0.033268
0.023483
0.039139
0.037182
0.050881
0.04501
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0.015656
0.013699
0.017613
0.019569
0.019569
0.029354
0.031311
0.029354
0.039139
0.027397
0.015656
0.027397
0.046967
1
8,040
G
G
G
C
C
A
C
C
T
C
C
C
C
G
A
T
T
T
T
G
C
A
A
A
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C
T
C
C
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T
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A
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G
C
C
A
T
A
C
A
A
A
T
A
G
C
A
A
T
T
G
C
A
T
C
A
C
0.050881
0.027397
0.046967
0.02544
0.027397
0.02544
0.011742
0.027397
0.041096
0.035225
0.054795
0.017613
0.023483
0.027397
0.04501
0.035225
0.043053
0.043053
0.037182
0.013699
0.009785
0.011742
0.017613
0.050881
0.041096
0.013699
0.041096
0.048924
0.039139
0.013699
0.013699
0.039139
1
8,041
C
T
C
C
A
T
G
A
G
A
A
A
C
T
T
A
A
T
A
G
A
C
A
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C
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C
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C
T
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C
A
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C
C
A
C
G
C
C
T
G
T
T
C
A
T
A
A
C
A
A
C
T
0.050881
0.039139
0.033268
0.02544
0.035225
0.035225
0.007828
0.02544
0.046967
0.037182
0.039139
0.019569
0.02544
0.04501
0.033268
0.039139
0.050881
0.048924
0.027397
0.011742
0.007828
0.011742
0.015656
0.048924
0.043053
0.011742
0.04501
0.031311
0.033268
0.013699
0.021526
0.039139
1
8,042
A
C
A
G
C
A
A
G
C
T
G
C
G
C
C
G
C
C
T
C
A
T
G
A
C
C
T
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C
G
C
C
T
G
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C
C
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C
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C
T
C
T
C
C
A
A
G
G
C
C
T
G
C
G
T
G
G
A
C
A
0.029354
0.02544
0.029354
0.015656
0.062622
0.031311
0.013699
0.023483
0.023483
0.039139
0.050881
0.011742
0.017613
0.033268
0.033268
0.048924
0.074364
0.04501
0.029354
0.015656
0.015656
0.037182
0.001957
0.031311
0.023483
0.037182
0.056751
0.039139
0.043053
0.019569
0.013699
0.027397
1
8,043
G
G
G
T
C
C
A
C
G
C
A
G
G
C
C
T
T
G
G
A
G
A
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C
A
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G
C
A
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C
C
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G
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A
G
G
T
C
A
T
G
A
G
G
C
G
G
C
G
C
A
G
C
T
T
G
C
T
A
0.029354
0.02544
0.029354
0.015656
0.060665
0.031311
0.013699
0.023483
0.023483
0.039139
0.050881
0.011742
0.017613
0.033268
0.033268
0.048924
0.074364
0.046967
0.029354
0.015656
0.015656
0.037182
0.001957
0.031311
0.023483
0.037182
0.056751
0.039139
0.043053
0.019569
0.013699
0.027397
1
8,044
T
C
C
T
G
T
C
T
T
C
C
T
C
C
A
A
C
G
T
G
G
C
T
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A
A
C
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C
T
C
T
T
G
G
T
A
A
T
A
T
A
G
C
C
G
G
T
A
0.033268
0.02544
0.041096
0.017613
0.031311
0.031311
0.017613
0.029354
0.029354
0.039139
0.048924
0.021526
0.019569
0.029354
0.033268
0.043053
0.048924
0.058708
0.058708
0.017613
0.009785
0.005871
0.017613
0.041096
0.037182
0.019569
0.029354
0.050881
0.043053
0.021526
0.013699
0.035225
1
8,045
G
A
T
C
A
A
C
C
G
G
G
C
T
G
C
C
C
G
C
T
G
C
G
T
G
C
G
C
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G
G
G
C
C
C
C
C
A
A
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G
A
G
A
A
C
A
A
G
T
T
T
G
C
T
G
T
G
G
G
C
A
G
C
G
T
0.007828
0.021526
0.013699
0.009785
0.039139
0.031311
0.019569
0.017613
0.033268
0.035225
0.054795
0.007828
0.029354
0.039139
0.015656
0.04501
0.064579
0.058708
0.076321
0.031311
0.013699
0.02544
0.011742
0.048924
0.021526
0.027397
0.037182
0.062622
0.050881
0.013699
0.005871
0.029354
1
8,046
G
G
C
C
A
C
G
C
G
G
C
T
C
C
C
G
C
T
G
G
C
T
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A
G
A
A
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G
C
C
G
C
A
G
C
T
A
C
T
G
C
T
G
G
A
T
T
A
0.013699
0.013699
0.023483
0.007828
0.027397
0.037182
0.017613
0.027397
0.029354
0.052838
0.060665
0.003914
0.02544
0.021526
0.019569
0.046967
0.07045
0.050881
0.04501
0.027397
0.015656
0.031311
0.017613
0.058708
0.021526
0.023483
0.037182
0.058708
0.041096
0.02544
0.003914
0.043053
1
8,047
G
T
C
C
G
A
T
C
T
G
G
A
G
C
T
C
G
T
G
G
C
C
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A
A
T
C
A
A
T
T
A
T
C
T
T
T
A
T
T
T
T
T
G
C
T
G
G
C
T
A
T
G
A
A
A
C
C
A
C
G
A
G
C
A
C
0.074364
0.019569
0.041096
0.052838
0.02544
0.027397
0.003914
0.027397
0.050881
0.02544
0.048924
0.02544
0.039139
0.039139
0.021526
0.033268
0.04501
0.037182
0.027397
0.001957
0.009785
0
0.019569
0.04501
0.056751
0.009785
0.02544
0.019569
0.041096
0.021526
0.035225
0.048924
1
8,048
G
G
G
A
G
G
G
G
G
G
C
T
G
C
C
G
G
C
T
G
T
G
C
T
G
G
T
G
C
A
C
A
T
A
G
G
T
G
A
T
G
T
G
C
T
G
G
G
C
C
A
A
C
C
T
G
G
A
C
A
G
A
G
G
G
C
0.056751
0.02544
0.033268
0.019569
0.04501
0.037182
0.011742
0.015656
0.02544
0.046967
0.058708
0.009785
0.013699
0.033268
0.019569
0.056751
0.050881
0.052838
0.060665
0.013699
0.001957
0.011742
0.021526
0.041096
0.043053
0.019569
0.029354
0.033268
0.054795
0.007828
0.015656
0.033268
1
8,049
G
G
T
C
T
C
C
A
G
G
C
T
G
G
G
C
A
A
T
C
C
T
T
G
T
G
T
T
C
T
C
T
C
C
T
T
C
T
A
C
C
A
G
C
A
C
C
G
T
G
A
T
A
C
T
A
C
G
A
G
G
G
A
T
A
G
0.043053
0.023483
0.041096
0.027397
0.035225
0.037182
0.009785
0.023483
0.039139
0.023483
0.074364
0.009785
0.027397
0.017613
0.037182
0.041096
0.046967
0.048924
0.064579
0.003914
0.003914
0.005871
0.027397
0.043053
0.046967
0.021526
0.029354
0.023483
0.066536
0.019569
0.007828
0.029354
1
8,050
T
C
C
A
A
G
G
G
G
A
G
A
A
A
G
A
C
C
C
A
C
T
T
T
C
T
C
C
T
C
A
C
C
T
C
T
C
A
G
C
T
C
T
G
A
C
T
T
C
C
C
C
A
C
A
C
A
A
A
A
C
T
C
T
T
T
0.019569
0.021526
0.041096
0.017613
0.017613
0.037182
0.007828
0.021526
0.078278
0.033268
0.066536
0.001957
0.023483
0.027397
0.031311
0.021526
0.050881
0.039139
0.043053
0.015656
0.017613
0.013699
0.009785
0.097847
0.037182
0.037182
0.031311
0.027397
0.056751
0.001957
0.009785
0.043053
1
8,051
C
C
T
G
C
C
A
G
C
T
G
C
T
A
A
C
G
G
A
T
G
A
G
G
T
C
A
G
C
T
A
C
C
G
C
A
T
C
A
A
A
G
A
G
A
T
C
G
C
A
C
A
G
G
T
G
A
C
C
C
G
G
C
C
C
T
0.017613
0.013699
0.041096
0.015656
0.031311
0.033268
0.015656
0.011742
0.050881
0.04501
0.052838
0
0.02544
0.041096
0.017613
0.033268
0.058708
0.048924
0.068493
0.02544
0.011742
0.013699
0.013699
0.046967
0.04501
0.039139
0.029354
0.04501
0.048924
0.005871
0.007828
0.04501
1
8,052
G
C
T
C
G
T
C
T
C
T
C
T
C
C
T
C
C
G
A
G
C
T
G
T
A
G
A
T
C
T
C
C
T
G
C
C
G
C
A
G
C
T
T
T
T
C
C
G
C
C
G
C
C
C
G
G
A
T
G
T
A
G
T
C
C
G
0.003914
0.001957
0.011742
0.001957
0.023483
0.027397
0.013699
0.019569
0.033268
0.035225
0.068493
0.003914
0.017613
0.023483
0.003914
0.027397
0.060665
0.041096
0.119374
0.048924
0.017613
0.060665
0.017613
0.066536
0.009785
0.039139
0.039139
0.060665
0.072407
0.015656
0.001957
0.011742
1
8,053
A
G
T
C
A
C
C
A
C
C
G
T
C
C
C
A
G
C
T
G
A
T
G
A
A
G
A
G
G
A
G
A
C
T
T
C
T
G
C
G
G
G
G
C
C
G
G
A
A
G
C
C
T
G
G
G
G
A
C
A
G
A
G
G
G
A
0.007828
0.009785
0.033268
0.007828
0.02544
0.04501
0.019569
0.02544
0.048924
0.04501
0.058708
0.001957
0.013699
0.011742
0.02544
0.052838
0.064579
0.062622
0.088063
0.017613
0.003914
0.009785
0.015656
0.064579
0.019569
0.037182
0.033268
0.046967
0.046967
0.015656
0.005871
0.035225
1
8,054
G
G
T
C
G
A
T
G
A
G
G
C
C
G
G
G
A
A
G
G
T
C
G
G
A
G
A
G
C
A
G
C
T
G
C
C
G
C
T
G
G
A
G
G
A
C
C
C
T
G
A
C
G
T
C
T
A
C
T
G
C
C
C
C
T
G
0.001957
0.005871
0.009785
0.005871
0.013699
0.033268
0.039139
0.013699
0.015656
0.046967
0.048924
0
0.015656
0.009785
0.005871
0.046967
0.054795
0.04501
0.101761
0.062622
0.02544
0.091977
0.011742
0.048924
0.015656
0.035225
0.039139
0.07045
0.052838
0.011742
0
0.019569
1
8,055
C
C
T
T
C
G
G
G
A
A
C
G
G
G
T
G
G
C
A
G
G
C
T
C
G
G
C
C
G
G
G
A
T
G
G
C
C
G
C
T
C
T
G
A
C
T
C
A
G
G
A
C
A
T
T
C
G
C
G
C
G
G
C
G
C
A
0.062622
0.009785
0.017613
0.005871
0.011742
0.027397
0.027397
0.017613
0.027397
0.043053
0.04501
0
0.009785
0.007828
0.007828
0.035225
0.046967
0.041096
0.097847
0.056751
0.023483
0.080235
0.007828
0.060665
0.021526
0.037182
0.027397
0.056751
0.060665
0.003914
0.003914
0.017613
1
8,056
T
C
A
G
G
G
G
C
A
C
T
T
T
C
G
C
T
C
C
A
C
G
C
A
C
T
G
C
T
T
C
C
C
G
C
C
C
T
C
C
T
C
A
T
A
T
T
C
C
T
G
C
T
T
G
G
A
G
A
T
C
C
A
C
A
A
0.035225
0.015656
0.037182
0.021526
0.027397
0.035225
0.003914
0.021526
0.029354
0.017613
0.078278
0.017613
0.02544
0.031311
0.023483
0.050881
0.041096
0.054795
0.105675
0.005871
0.003914
0.005871
0.001957
0.066536
0.035225
0.015656
0.027397
0.031311
0.072407
0.007828
0.015656
0.037182
1
8,057
T
C
C
T
C
T
C
A
C
C
A
G
T
G
A
G
G
C
C
A
G
G
A
T
G
G
A
A
C
C
C
C
C
G
A
T
C
C
A
G
G
G
G
C
T
G
A
A
C
T
T
G
C
G
C
T
C
C
A
T
G
G
T
G
C
T
0.02544
0.02544
0.035225
0.017613
0.037182
0.031311
0.003914
0.031311
0.031311
0.033268
0.054795
0.001957
0.011742
0.035225
0.023483
0.037182
0.072407
0.062622
0.097847
0.011742
0.007828
0.007828
0.009785
0.033268
0.050881
0.037182
0.027397
0.04501
0.050881
0.003914
0.003914
0.041096
1
8,058
C
A
G
A
A
C
G
T
A
G
C
C
G
T
C
A
T
G
T
A
C
T
G
G
A
A
T
G
G
C
C
G
T
G
G
T
G
T
G
G
G
T
G
G
C
T
C
C
A
C
T
G
T
C
C
A
G
C
A
C
G
A
G
G
C
G
0.035225
0.007828
0.031311
0.005871
0.019569
0.031311
0.013699
0.033268
0.048924
0.037182
0.043053
0
0.031311
0.041096
0.021526
0.035225
0.068493
0.074364
0.068493
0.019569
0.009785
0.003914
0.011742
0.048924
0.017613
0.041096
0.04501
0.054795
0.050881
0.013699
0.005871
0.029354
1
8,059
T
T
C
C
T
G
C
C
T
T
C
T
T
C
T
T
A
T
G
C
A
A
G
A
C
G
G
C
T
G
T
G
C
T
C
A
C
C
G
C
G
T
A
T
C
C
T
C
T
G
G
A
C
T
G
A
G
C
T
G
C
T
C
T
G
T
0.007828
0.017613
0.023483
0.005871
0.066536
0.027397
0.013699
0.035225
0.039139
0.048924
0.039139
0.009785
0.023483
0.019569
0.015656
0.088063
0.074364
0.04501
0.056751
0.023483
0.007828
0.011742
0.005871
0.058708
0.027397
0.02544
0.039139
0.041096
0.039139
0.011742
0.003914
0.046967
1
8,060
A
G
T
G
C
A
T
G
G
C
A
T
A
G
A
T
C
T
T
T
G
C
C
A
G
G
T
G
C
C
C
A
C
G
G
A
G
G
G
T
C
C
T
C
C
G
G
G
T
C
C
T
C
A
T
C
T
G
G
A
T
T
C
T
C
A
0.017613
0.009785
0.021526
0.005871
0.031311
0.035225
0.015656
0.02544
0.054795
0.039139
0.048924
0.003914
0.023483
0.02544
0.015656
0.043053
0.082192
0.064579
0.058708
0.02544
0.009785
0.027397
0.011742
0.052838
0.015656
0.041096
0.046967
0.058708
0.04501
0.013699
0.005871
0.023483
1
8,061
T
G
C
C
C
C
A
C
C
C
C
G
C
A
G
C
C
C
G
C
G
C
C
A
C
C
C
T
A
C
C
T
T
G
T
T
G
G
T
G
G
T
G
T
A
G
C
T
G
T
C
C
C
A
G
A
T
G
A
T
G
A
G
C
T
C
0.007828
0.017613
0.021526
0.001957
0.035225
0.04501
0.011742
0.013699
0.02544
0.054795
0.068493
0.001957
0.017613
0.017613
0.021526
0.052838
0.074364
0.062622
0.09002
0.021526
0.001957
0.039139
0.017613
0.048924
0.017613
0.021526
0.037182
0.058708
0.046967
0.013699
0.001957
0.031311
1
8,062
C
T
G
C
C
C
C
A
C
C
C
C
G
C
A
G
C
C
C
G
C
G
C
C
A
C
C
C
T
A
C
C
T
T
G
T
T
G
G
T
G
G
T
G
T
A
G
C
T
G
T
C
C
C
A
G
A
T
G
A
T
G
A
G
C
G
0.007828
0.017613
0.021526
0.001957
0.035225
0.04501
0.011742
0.013699
0.02544
0.054795
0.068493
0.001957
0.017613
0.017613
0.021526
0.052838
0.074364
0.062622
0.088063
0.021526
0.001957
0.039139
0.017613
0.048924
0.017613
0.021526
0.037182
0.060665
0.046967
0.013699
0.001957
0.031311
1
8,063
A
G
G
C
C
T
C
C
C
C
T
G
T
G
T
A
C
A
G
C
T
T
C
A
G
C
T
T
T
C
C
C
C
G
G
A
G
G
A
A
A
T
T
G
G
A
G
T
A
G
A
C
T
C
G
G
A
A
G
A
G
T
T
T
G
T
0.015656
0.015656
0.037182
0.011742
0.046967
0.021526
0.003914
0.031311
0.043053
0.04501
0.064579
0.005871
0.017613
0.019569
0.021526
0.041096
0.074364
0.04501
0.056751
0.021526
0.011742
0.013699
0.007828
0.064579
0.037182
0.031311
0.037182
0.037182
0.07045
0.015656
0.005871
0.027397
1
8,064
T
T
G
G
C
A
G
A
A
A
G
A
C
C
G
G
A
A
T
G
C
C
C
G
G
C
C
C
C
G
C
T
T
C
C
C
C
C
A
G
G
T
G
G
T
C
A
G
C
G
C
C
C
T
G
G
A
C
A
A
G
A
T
G
A
C
0.023483
0.015656
0.029354
0.021526
0.021526
0.035225
0.003914
0.015656
0.035225
0.033268
0.062622
0.003914
0.02544
0.027397
0.02544
0.027397
0.060665
0.066536
0.093933
0.037182
0.001957
0.015656
0.013699
0.04501
0.037182
0.02544
0.029354
0.058708
0.072407
0.007828
0.003914
0.023483
1
8,065
A
C
C
T
T
T
T
C
T
C
C
T
T
T
T
T
C
T
G
C
A
G
G
G
A
G
G
A
A
A
G
A
T
T
C
C
C
A
T
C
C
G
A
T
G
G
A
C
T
G
C
C
C
C
G
G
A
G
G
C
C
A
T
T
G
G
0.027397
0.023483
0.027397
0.013699
0.017613
0.035225
0.009785
0.04501
0.033268
0.029354
0.054795
0
0.027397
0.02544
0.02544
0.043053
0.054795
0.056751
0.072407
0.02544
0.009785
0.005871
0.011742
0.068493
0.033268
0.023483
0.029354
0.035225
0.066536
0.017613
0.005871
0.04501
1
8,066
T
G
T
T
G
A
C
T
A
G
G
A
T
G
T
T
G
C
G
A
G
C
A
G
C
C
A
G
G
T
C
T
C
G
G
T
G
G
A
C
G
T
A
G
C
T
C
A
T
C
T
C
G
G
C
A
A
G
G
T
A
C
C
G
C
T
0.027397
0.021526
0.021526
0.005871
0.029354
0.041096
0.015656
0.021526
0.029354
0.054795
0.058708
0.007828
0.023483
0.02544
0.021526
0.041096
0.068493
0.058708
0.07045
0.017613
0.023483
0.009785
0.017613
0.054795
0.017613
0.027397
0.046967
0.04501
0.048924
0.015656
0.009785
0.021526
1
8,067
A
G
T
T
T
C
T
G
A
G
C
G
A
G
G
C
C
T
C
C
A
T
C
A
T
G
G
G
C
C
A
G
T
T
C
G
A
G
C
A
C
C
C
C
A
A
T
A
T
C
A
T
C
C
G
C
C
T
G
G
A
G
G
G
C
C
0.013699
0.019569
0.037182
0.007828
0.021526
0.043053
0.013699
0.019569
0.031311
0.041096
0.064579
0.003914
0.013699
0.021526
0.021526
0.052838
0.054795
0.058708
0.066536
0.035225
0.011742
0.029354
0.003914
0.060665
0.033268
0.021526
0.031311
0.07045
0.04501
0.003914
0.007828
0.039139
1
8,068
C
G
A
A
G
C
C
C
A
G
C
A
G
A
G
C
A
G
C
A
C
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G
G
A
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C
T
C
C
A
T
G
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C
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C
C
T
C
A
C
T
C
G
G
G
T
A
G
G
A
T
C
C
G
A
A
C
T
G
C
0.019569
0.017613
0.017613
0
0.009785
0.023483
0.021526
0.035225
0.017613
0.027397
0.033268
0.003914
0.009785
0.009785
0.019569
0.035225
0.037182
0.043053
0.127202
0.080235
0.023483
0.093933
0.009785
0.048924
0.017613
0.02544
0.035225
0.086106
0.046967
0.009785
0
0.013699
1
8,069
G
A
C
C
T
T
C
C
C
A
G
C
A
A
C
A
T
A
T
T
C
A
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C
A
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C
A
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G
T
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C
C
A
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C
A
G
T
G
C
T
G
G
G
A
C
C
A
C
T
C
A
C
A
G
0.015656
0.033268
0.019569
0.023483
0.062622
0.052838
0.005871
0.043053
0.033268
0.033268
0.039139
0.009785
0.011742
0.041096
0.029354
0.068493
0.068493
0.064579
0.021526
0.007828
0.005871
0
0.017613
0.043053
0.046967
0.033268
0.029354
0.011742
0.046967
0.029354
0.001957
0.048924
1
8,070
C
A
A
C
T
T
C
C
T
G
C
A
T
C
T
C
T
C
T
A
A
G
G
A
T
T
A
C
T
C
C
A
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C
T
C
A
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G
T
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C
A
A
T
C
T
C
T
G
C
T
T
C
T
C
C
C
A
A
T
G
T
G
T
0.105675
0.037182
0.037182
0.082192
0.041096
0.015656
0.011742
0.035225
0.039139
0.019569
0.017613
0.060665
0.033268
0.027397
0.048924
0.021526
0.033268
0.023483
0.017613
0.001957
0
0.001957
0.02544
0.015656
0.046967
0.011742
0.019569
0.005871
0.021526
0.031311
0.062622
0.046967
1
8,071
G
G
G
A
G
A
A
G
C
A
G
A
G
A
T
T
G
A
A
C
G
T
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C
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A
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G
A
T
G
C
A
G
G
A
A
G
T
T
G
A
A
A
C
C
A
G
0.105675
0.039139
0.037182
0.082192
0.039139
0.015656
0.011742
0.035225
0.039139
0.019569
0.017613
0.060665
0.033268
0.027397
0.046967
0.021526
0.033268
0.023483
0.017613
0.001957
0
0.001957
0.027397
0.015656
0.046967
0.011742
0.019569
0.005871
0.021526
0.029354
0.064579
0.046967
1
8,072
T
T
A
A
A
C
A
G
G
T
T
C
A
A
C
T
C
C
A
A
T
T
T
G
T
G
A
A
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A
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G
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C
A
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G
T
T
A
T
G
C
T
A
T
A
A
T
A
G
A
A
G
G
A
C
0.09002
0.046967
0.046967
0.048924
0.058708
0.017613
0.005871
0.037182
0.043053
0.027397
0.02544
0.046967
0.027397
0.043053
0.048924
0.017613
0.037182
0.023483
0.005871
0
0.007828
0.001957
0.027397
0.021526
0.054795
0.017613
0.019569
0.005871
0.02544
0.035225
0.039139
0.04501
1
8,073
A
T
C
A
A
A
T
G
T
A
A
G
C
T
T
T
T
A
C
C
T
A
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G
G
A
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T
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T
C
T
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T
T
C
C
A
A
G
A
A
A
A
C
A
A
T
A
C
A
T
G
A
T
A
A
C
G
0.064579
0.031311
0.041096
0.046967
0.050881
0.035225
0.003914
0.017613
0.039139
0.029354
0.043053
0.033268
0.027397
0.041096
0.039139
0.029354
0.046967
0.041096
0.02544
0.007828
0.011742
0.003914
0.017613
0.02544
0.029354
0.015656
0.039139
0.033268
0.023483
0.031311
0.050881
0.023483
1
8,074
T
G
A
G
C
T
G
T
T
G
A
C
A
G
A
G
T
T
G
T
A
G
A
T
G
G
T
G
G
C
T
T
C
A
T
G
G
A
A
C
T
G
G
A
A
A
G
G
G
G
A
G
C
A
G
C
C
A
A
T
G
C
T
G
T
T
0.074364
0.037182
0.037182
0.048924
0.04501
0.02544
0.001957
0.017613
0.052838
0.037182
0.043053
0.031311
0.023483
0.037182
0.035225
0.019569
0.052838
0.037182
0.02544
0.003914
0.005871
0
0.017613
0.04501
0.037182
0.013699
0.035225
0.02544
0.033268
0.021526
0.050881
0.027397
1
8,075
G
C
A
C
T
G
A
G
G
G
A
C
C
A
G
A
T
A
A
T
T
C
C
A
A
C
T
C
A
C
A
C
C
G
A
A
G
T
C
A
G
T
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G
A
A
T
A
C
T
G
C
A
C
A
T
G
A
A
T
T
T
G
A
T
A
0.074364
0.023483
0.050881
0.04501
0.043053
0.031311
0
0.039139
0.043053
0.027397
0.029354
0.033268
0.039139
0.035225
0.037182
0.039139
0.052838
0.04501
0.017613
0.001957
0.001957
0
0.019569
0.013699
0.052838
0.017613
0.029354
0.013699
0.031311
0.035225
0.029354
0.046967
1
8,076
G
C
A
G
T
T
T
C
C
C
T
G
G
A
T
G
C
A
T
C
T
C
C
C
A
T
G
G
C
C
A
C
T
G
C
A
C
A
T
G
T
C
T
A
T
G
C
A
G
C
C
A
T
C
C
C
C
G
A
T
A
T
A
G
A
C
0.07045
0.035225
0.052838
0.041096
0.052838
0.007828
0.005871
0.029354
0.054795
0.031311
0.021526
0.035225
0.039139
0.062622
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0.023483
0.039139
0.033268
0.013699
0.005871
0.005871
0.001957
0.021526
0.021526
0.066536
0.015656
0.033268
0.011742
0.041096
0.021526
0.027397
0.041096
1
8,077
T
C
A
C
A
G
G
A
G
A
A
C
A
C
A
T
G
C
A
T
T
T
T
T
A
C
C
G
T
T
A
T
T
A
T
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A
G
G
T
T
G
C
C
A
G
A
G
T
C
T
G
A
A
T
C
T
T
G
T
A
G
C
A
T
C
0.064579
0.039139
0.041096
0.041096
0.062622
0.021526
0.007828
0.033268
0.04501
0.021526
0.031311
0.033268
0.033268
0.04501
0.035225
0.043053
0.041096
0.035225
0.017613
0.005871
0.005871
0
0.019569
0.029354
0.04501
0.015656
0.027397
0.019569
0.031311
0.027397
0.041096
0.039139
1
8,078
C
C
C
C
T
G
A
T
C
A
G
C
C
T
G
G
T
G
A
A
G
G
A
G
T
T
T
T
G
T
T
G
C
A
T
T
A
T
T
C
T
T
A
T
G
A
T
A
A
T
G
G
G
A
T
A
A
C
T
T
G
G
A
A
A
A
0.080235
0.031311
0.02544
0.072407
0.04501
0.017613
0.003914
0.027397
0.048924
0.021526
0.015656
0.056751
0.035225
0.060665
0.039139
0.02544
0.035225
0.039139
0.023483
0
0
0.003914
0.023483
0.029354
0.046967
0.015656
0.02544
0.007828
0.029354
0.021526
0.043053
0.048924
1
8,079
A
C
C
C
T
G
C
C
T
T
C
A
C
T
C
A
C
C
T
G
G
A
T
T
G
T
G
A
G
C
T
G
T
C
A
A
G
G
A
A
A
G
A
T
G
T
A
A
T
T
A
G
C
T
G
A
C
G
C
C
G
C
C
C
A
C
0.09002
0.035225
0.033268
0.056751
0.035225
0.029354
0.003914
0.035225
0.037182
0.029354
0.033268
0.039139
0.02544
0.035225
0.035225
0.02544
0.043053
0.046967
0.019569
0.003914
0
0.003914
0.031311
0.027397
0.033268
0.021526
0.011742
0.029354
0.02544
0.021526
0.056751
0.04501
1
8,080
T
T
A
C
A
T
A
C
C
T
C
A
T
G
T
T
T
G
T
G
T
A
T
T
T
T
T
T
T
A
G
C
T
T
G
A
A
T
T
T
T
C
T
C
G
G
G
G
C
C
T
T
A
T
G
A
T
G
C
T
G
G
T
T
C
C
0.064579
0.031311
0.048924
0.043053
0.043053
0.021526
0.003914
0.039139
0.054795
0.027397
0.02544
0.043053
0.027397
0.050881
0.039139
0.02544
0.035225
0.043053
0.009785
0.003914
0.001957
0.001957
0.029354
0.033268
0.052838
0.015656
0.019569
0.021526
0.029354
0.035225
0.033268
0.04501
1
8,081
T
C
C
C
C
A
T
C
G
A
G
T
T
C
G
T
G
C
T
G
C
C
C
A
C
C
A
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C
C
A
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C
G
C
A
A
A
T
G
C
A
A
G
A
G
C
C
C
C
G
A
A
A
C
G
G
C
G
C
T
G
C
T
G
A
0.015656
0.011742
0.029354
0.005871
0.021526
0.029354
0.02544
0.023483
0.035225
0.048924
0.04501
0.017613
0.019569
0.027397
0.013699
0.04501
0.060665
0.056751
0.037182
0.043053
0.017613
0.046967
0.013699
0.048924
0.029354
0.021526
0.052838
0.066536
0.048924
0.019569
0.003914
0.017613
1
8,082
A
G
A
A
C
A
G
G
A
T
G
A
T
C
A
G
T
A
G
G
T
T
T
G
T
G
T
G
A
T
G
A
C
G
A
A
G
G
G
C
T
A
G
A
T
A
A
G
C
C
T
T
A
A
C
A
C
A
G
A
T
G
T
C
C
G
0.062622
0.04501
0.048924
0.031311
0.052838
0.011742
0.003914
0.037182
0.048924
0.017613
0.041096
0.033268
0.050881
0.052838
0.035225
0.015656
0.04501
0.021526
0.019569
0.005871
0.005871
0
0.023483
0.027397
0.04501
0.015656
0.029354
0.015656
0.039139
0.029354
0.043053
0.04501
1
8,083
G
T
T
T
G
A
T
G
C
C
A
A
G
A
A
C
A
A
G
A
T
G
T
A
G
A
A
A
C
C
A
A
T
T
A
A
A
C
T
G
C
A
C
A
G
T
C
C
A
T
C
C
T
T
T
G
T
C
T
C
T
G
C
A
A
C
0.066536
0.043053
0.048924
0.043053
0.048924
0.009785
0.001957
0.029354
0.048924
0.033268
0.033268
0.02544
0.048924
0.050881
0.046967
0.017613
0.041096
0.027397
0.015656
0.003914
0.009785
0
0.035225
0.019569
0.050881
0.015656
0.039139
0.017613
0.037182
0.013699
0.035225
0.041096
1
8,084
A
A
G
T
T
C
A
A
C
A
G
C
T
C
T
T
T
G
G
G
C
A
A
T
A
G
C
C
T
C
A
G
T
G
T
T
G
T
C
A
A
A
G
A
C
A
A
A
A
T
C
C
A
A
G
C
A
T
T
C
A
A
A
G
T
G
0.125245
0.029354
0.052838
0.046967
0.04501
0.023483
0
0.029354
0.031311
0.037182
0.029354
0.027397
0.023483
0.043053
0.048924
0.029354
0.033268
0.02544
0.017613
0.005871
0.003914
0.005871
0.015656
0.027397
0.037182
0.013699
0.037182
0.017613
0.019569
0.02544
0.04501
0.046967
1
8,085
T
G
C
C
A
G
T
G
G
G
A
A
T
G
A
G
C
T
C
T
G
A
C
T
G
G
A
A
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A
A
C
C
T
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A
A
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A
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G
T
T
T
T
G
A
T
C
C
A
G
T
T
A
T
A
G
T
T
T
C
A
0.109589
0.035225
0.039139
0.080235
0.04501
0.013699
0
0.033268
0.039139
0.033268
0.019569
0.099804
0.033268
0.029354
0.039139
0.017613
0.02544
0.013699
0.005871
0
0.001957
0.001957
0.043053
0.017613
0.033268
0.009785
0.015656
0.003914
0.015656
0.027397
0.080235
0.037182
1
8,086
T
C
C
C
T
C
C
T
C
G
C
T
G
T
C
C
T
C
T
G
G
C
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C
A
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C
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C
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C
G
G
C
A
G
G
T
C
G
G
A
G
C
C
G
C
C
G
C
C
0.003914
0.011742
0.021526
0
0.019569
0.029354
0.02544
0.007828
0.027397
0.068493
0.054795
0
0.007828
0.007828
0.009785
0.027397
0.07045
0.033268
0.072407
0.054795
0.037182
0.097847
0.009785
0.056751
0.019569
0.029354
0.058708
0.07045
0.043053
0.013699
0.003914
0.005871
1
8,087
T
G
C
G
G
C
G
G
C
T
C
C
G
A
C
C
T
G
C
C
G
C
C
T
G
G
C
G
C
T
G
C
C
A
T
G
A
C
C
T
G
C
G
A
G
C
C
A
G
A
G
G
A
C
A
G
C
G
A
G
G
A
G
G
G
T
0.003914
0.011742
0.021526
0
0.019569
0.029354
0.02544
0.007828
0.027397
0.068493
0.054795
0
0.007828
0.007828
0.009785
0.027397
0.07045
0.031311
0.072407
0.054795
0.037182
0.099804
0.009785
0.056751
0.019569
0.029354
0.058708
0.07045
0.043053
0.013699
0.003914
0.005871
1
8,088
A
C
A
G
C
T
G
C
A
G
C
T
A
C
A
T
G
G
T
G
T
C
G
C
G
G
C
C
G
G
T
C
T
A
C
A
G
C
G
A
G
C
T
C
G
C
T
T
T
C
C
A
G
C
A
A
C
A
G
C
A
C
G
A
G
C
0.005871
0.007828
0.02544
0
0.019569
0.023483
0.023483
0.009785
0.029354
0.072407
0.052838
0
0.007828
0.007828
0.009785
0.021526
0.066536
0.035225
0.064579
0.060665
0.037182
0.101761
0.009785
0.062622
0.017613
0.033268
0.046967
0.074364
0.050881
0.013699
0.003914
0.003914
1
8,089
C
C
G
C
T
C
G
T
G
C
T
G
T
T
G
C
T
G
G
A
A
A
G
C
G
A
G
C
T
C
G
C
T
G
T
A
G
A
C
C
G
G
C
C
G
C
G
A
C
A
C
C
A
T
G
T
A
G
C
T
G
C
A
G
C
C
0.005871
0.007828
0.02544
0
0.019569
0.023483
0.021526
0.009785
0.031311
0.072407
0.052838
0
0.007828
0.007828
0.009785
0.021526
0.068493
0.035225
0.064579
0.058708
0.037182
0.101761
0.009785
0.062622
0.019569
0.033268
0.046967
0.072407
0.050881
0.013699
0.003914
0.003914
1
8,090
T
A
A
A
G
A
C
T
C
T
T
G
T
G
C
C
C
A
T
C
T
T
G
G
A
G
T
G
G
C
T
C
C
C
C
A
A
A
T
A
C
C
G
A
G
T
C
A
A
G
G
A
A
T
G
G
C
T
G
C
T
T
A
G
T
T
0.058708
0.035225
0.058708
0.029354
0.027397
0.02544
0.005871
0.046967
0.056751
0.031311
0.035225
0.02544
0.02544
0.021526
0.046967
0.029354
0.043053
0.048924
0.029354
0.003914
0.003914
0.001957
0.023483
0.043053
0.041096
0.019569
0.033268
0.023483
0.037182
0.021526
0.035225
0.031311
1