row_idx
int64
f_0_ref__32
string
f_1_ref__31
string
f_2_ref__30
string
f_3_ref__29
string
f_4_ref__28
string
f_5_ref__27
string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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f_36_ref__4
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string
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string
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string
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string
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string
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string
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string
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f_64_ref__32
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f_65_alt
string
f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
int64
9,091
C
A
A
A
A
C
G
C
A
G
A
A
G
T
C
A
C
A
C
A
A
G
A
C
A
C
A
C
A
A
A
C
C
T
G
T
T
G
A
A
C
A
C
T
T
G
A
T
G
G
G
T
G
A
G
G
A
A
C
G
G
G
C
T
G
G
0.052838
0.031311
0.035225
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0.009785
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1
9,092
T
T
G
A
A
C
A
C
T
T
G
A
T
G
G
G
T
G
A
G
G
A
A
C
G
G
G
C
T
G
G
T
C
C
T
C
T
T
G
A
A
C
A
C
A
G
A
C
C
C
T
G
G
A
A
T
A
C
C
T
C
T
G
C
A
G
0.054795
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0.007828
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1
9,093
C
C
A
T
T
T
T
G
T
T
T
G
T
G
T
T
T
C
T
G
T
A
G
C
T
T
G
G
T
A
T
T
T
C
T
C
T
T
G
A
T
G
A
A
A
C
A
G
T
C
A
A
T
G
A
A
A
A
A
G
A
T
C
T
G
C
0.066536
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0
0.005871
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0.02544
0.021526
0.017613
0.04501
0.019569
0.027397
0.043053
1
9,094
T
T
T
A
A
A
T
G
T
T
C
T
T
A
T
C
T
T
T
T
A
G
G
C
C
C
T
C
T
T
G
G
C
G
A
A
T
A
T
G
G
C
T
G
C
C
A
T
G
T
T
T
G
C
A
A
T
C
T
A
C
C
A
T
G
T
0.084149
0.033268
0.037182
0.07045
0.041096
0.023483
0.007828
0.031311
0.02544
0.013699
0.031311
0.048924
0.031311
0.052838
0.060665
0.017613
0.021526
0.041096
0.023483
0
0.007828
0.003914
0.023483
0.019569
0.031311
0.02544
0.02544
0.019569
0.029354
0.027397
0.04501
0.04501
1
9,095
T
C
G
G
A
G
A
G
A
C
A
A
G
G
C
T
A
C
C
A
G
C
A
A
C
A
T
C
T
G
T
A
C
A
G
C
T
C
A
G
G
T
A
A
A
T
C
A
C
A
C
G
T
C
T
G
A
C
C
T
G
A
C
T
A
T
0.037182
0.019569
0.041096
0.058708
0.043053
0.027397
0.013699
0.023483
0.048924
0.043053
0.031311
0.027397
0.029354
0.041096
0.039139
0.043053
0.050881
0.039139
0.013699
0.003914
0.005871
0
0.019569
0.035225
0.048924
0.011742
0.043053
0.027397
0.021526
0.033268
0.029354
0.048924
1
9,096
T
C
A
G
G
T
C
A
G
A
C
G
T
G
T
G
A
T
T
T
A
C
C
T
G
A
G
C
T
G
T
A
C
A
G
A
T
G
T
T
G
C
T
G
G
T
A
G
C
C
T
T
G
T
C
T
C
T
C
C
G
A
A
T
G
T
0.037182
0.019569
0.041096
0.058708
0.043053
0.027397
0.013699
0.02544
0.048924
0.041096
0.031311
0.027397
0.029354
0.041096
0.039139
0.043053
0.050881
0.039139
0.013699
0.003914
0.005871
0
0.019569
0.033268
0.048924
0.011742
0.043053
0.02544
0.021526
0.035225
0.031311
0.048924
1
9,097
A
C
A
C
A
T
T
C
G
G
A
G
A
G
A
C
A
A
G
G
C
T
A
C
C
A
G
C
A
A
C
A
T
C
T
G
T
A
C
A
G
C
T
C
A
G
G
T
A
A
A
T
C
A
C
A
C
G
T
C
T
G
A
C
C
C
0.037182
0.019569
0.041096
0.058708
0.043053
0.027397
0.013699
0.02544
0.048924
0.041096
0.031311
0.027397
0.031311
0.041096
0.039139
0.043053
0.050881
0.037182
0.013699
0.003914
0.005871
0
0.019569
0.033268
0.048924
0.011742
0.043053
0.02544
0.019569
0.035225
0.031311
0.050881
1
9,098
C
T
G
T
A
C
A
G
A
T
G
T
T
G
C
T
G
G
T
A
G
C
C
T
T
G
T
C
T
C
T
C
C
G
A
A
T
G
T
G
T
T
G
C
T
C
C
C
T
G
G
T
T
T
G
A
A
G
A
G
C
A
A
G
A
T
0.066536
0.019569
0.039139
0.058708
0.041096
0.027397
0.015656
0.02544
0.048924
0.039139
0.02544
0.027397
0.029354
0.041096
0.037182
0.041096
0.046967
0.035225
0.013699
0.005871
0.005871
0
0.019569
0.033268
0.048924
0.013699
0.037182
0.017613
0.021526
0.035225
0.031311
0.050881
1
9,099
A
A
G
T
G
T
A
T
C
G
T
C
T
T
G
C
T
C
T
T
C
A
A
A
C
C
A
G
G
G
A
G
C
A
A
C
A
C
A
T
T
C
G
G
A
G
A
G
A
C
A
A
G
G
C
T
A
C
C
A
G
C
A
A
C
A
0.068493
0.021526
0.037182
0.058708
0.041096
0.02544
0.015656
0.027397
0.050881
0.039139
0.023483
0.027397
0.029354
0.041096
0.035225
0.039139
0.04501
0.033268
0.011742
0.005871
0.007828
0.001957
0.019569
0.037182
0.050881
0.013699
0.035225
0.017613
0.021526
0.035225
0.031311
0.050881
1
9,100
C
C
T
T
G
T
C
T
C
T
C
C
G
A
A
T
G
T
G
T
T
G
C
T
C
C
C
T
G
G
T
T
T
G
A
A
G
A
G
C
A
A
G
A
C
G
A
T
A
C
A
C
T
T
C
T
T
T
C
C
C
A
G
T
G
C
0.07045
0.021526
0.039139
0.056751
0.039139
0.02544
0.015656
0.027397
0.050881
0.039139
0.023483
0.027397
0.027397
0.039139
0.035225
0.039139
0.04501
0.035225
0.013699
0.005871
0.009785
0.003914
0.019569
0.037182
0.052838
0.013699
0.033268
0.019569
0.019569
0.033268
0.029354
0.050881
1
9,101
C
A
T
G
A
G
C
C
C
C
T
T
T
A
C
C
T
T
G
T
T
A
C
C
C
C
C
A
C
C
A
T
T
C
T
T
C
C
A
G
G
C
A
T
C
A
T
T
C
T
C
A
C
C
A
A
G
C
T
T
T
C
T
C
G
G
0.074364
0.021526
0.039139
0.058708
0.041096
0.019569
0
0.029354
0.050881
0.031311
0.033268
0.027397
0.029354
0.041096
0.043053
0.023483
0.039139
0.037182
0.041096
0.001957
0.007828
0.001957
0.029354
0.037182
0.050881
0.011742
0.023483
0.02544
0.027397
0.033268
0.02544
0.043053
1
9,102
A
G
A
T
G
C
A
C
A
A
A
G
C
T
A
A
A
A
G
G
T
C
A
G
T
A
G
C
A
C
A
G
C
A
G
G
C
C
A
G
G
C
T
C
T
A
G
A
A
A
G
G
A
A
G
T
G
A
G
A
G
A
A
A
A
T
0.056751
0.017613
0.039139
0.041096
0.037182
0.02544
0.001957
0.033268
0.04501
0.033268
0.043053
0.013699
0.02544
0.048924
0.02544
0.037182
0.046967
0.04501
0.043053
0.007828
0.003914
0.001957
0.023483
0.04501
0.050881
0.011742
0.035225
0.027397
0.043053
0.027397
0.021526
0.041096
1
9,103
C
C
T
G
T
T
C
C
T
G
A
A
C
T
G
A
G
A
A
A
T
A
C
A
T
T
A
C
C
A
T
C
C
T
G
A
G
T
T
C
T
C
C
A
G
T
A
A
G
T
T
C
C
G
C
A
A
A
A
T
C
G
T
C
T
G
0.064579
0.031311
0.021526
0.054795
0.041096
0.017613
0.003914
0.037182
0.060665
0.017613
0.027397
0.031311
0.037182
0.046967
0.031311
0.023483
0.048924
0.041096
0.019569
0.009785
0.007828
0.001957
0.023483
0.048924
0.04501
0.02544
0.033268
0.009785
0.050881
0.019569
0.031311
0.035225
1
9,104
A
A
C
T
G
C
T
C
A
G
T
G
C
C
A
C
A
G
A
C
G
A
T
T
T
T
G
C
G
G
A
A
C
T
T
A
C
T
G
G
A
G
A
A
C
T
C
A
G
G
A
T
G
G
T
A
A
T
G
T
A
T
T
T
C
G
0.064579
0.035225
0.021526
0.050881
0.041096
0.017613
0.003914
0.037182
0.058708
0.017613
0.027397
0.031311
0.037182
0.048924
0.033268
0.021526
0.046967
0.043053
0.019569
0.009785
0.007828
0.001957
0.023483
0.048924
0.04501
0.023483
0.033268
0.009785
0.052838
0.019569
0.031311
0.035225
1
9,105
T
G
C
C
A
T
T
T
C
A
A
G
C
A
A
A
A
A
C
C
A
G
A
T
C
T
G
G
A
G
A
T
C
G
T
A
T
A
T
T
G
G
C
A
T
G
G
G
C
T
A
T
T
A
T
A
A
C
T
G
C
T
C
A
G
T
0.078278
0.037182
0.019569
0.046967
0.048924
0.017613
0.003914
0.039139
0.054795
0.015656
0.023483
0.029354
0.035225
0.048924
0.041096
0.023483
0.046967
0.039139
0.019569
0.009785
0.009785
0.003914
0.015656
0.050881
0.035225
0.02544
0.033268
0.009785
0.04501
0.023483
0.029354
0.039139
1
9,106
G
G
A
C
A
A
A
G
A
C
C
A
G
A
G
A
G
A
G
A
T
G
C
T
G
C
A
G
A
C
C
T
T
G
G
G
G
C
T
G
G
C
G
G
T
A
A
G
G
A
C
C
T
C
C
A
C
C
C
G
G
C
C
C
T
G
0.019569
0.003914
0.029354
0.005871
0.017613
0.027397
0.019569
0.013699
0.027397
0.041096
0.052838
0
0.007828
0.009785
0.009785
0.035225
0.060665
0.048924
0.09002
0.07045
0.021526
0.076321
0.001957
0.043053
0.015656
0.029354
0.046967
0.101761
0.043053
0.011742
0.013699
0.003914
1
9,107
A
C
A
C
G
A
C
G
A
C
T
T
C
G
C
T
C
G
G
A
G
G
C
A
C
A
T
C
G
G
C
C
C
T
G
G
G
G
A
C
A
A
A
G
A
C
C
A
G
A
G
A
G
A
G
A
T
G
C
T
G
C
A
G
A
G
0.007828
0.001957
0.029354
0.003914
0.013699
0.027397
0.019569
0.011742
0.027397
0.04501
0.054795
0
0.007828
0.007828
0.009785
0.029354
0.064579
0.04501
0.09589
0.080235
0.019569
0.084149
0.001957
0.041096
0.013699
0.033268
0.048924
0.107632
0.04501
0.007828
0.009785
0.003914
1
9,108
C
G
G
G
C
C
G
G
G
G
C
A
G
G
G
G
A
C
G
G
T
G
G
C
C
G
C
G
G
C
C
A
T
G
C
A
G
T
C
C
T
G
T
G
C
C
A
G
G
G
C
G
T
G
G
G
G
G
C
T
G
C
G
C
C
C
0.007828
0.003914
0.023483
0.003914
0.021526
0.023483
0.011742
0.013699
0.023483
0.04501
0.04501
0
0.011742
0.015656
0.019569
0.027397
0.062622
0.056751
0.091977
0.076321
0.02544
0.097847
0
0.041096
0.007828
0.035225
0.041096
0.113503
0.041096
0.001957
0.003914
0.005871
1
9,109
C
G
G
G
C
C
G
G
G
G
C
A
G
G
G
G
A
C
G
G
T
G
G
C
C
G
C
G
G
C
C
A
T
G
C
A
G
T
C
C
T
G
T
G
C
C
A
G
G
G
C
G
T
G
G
G
G
G
C
T
G
C
G
C
C
A
0.007828
0.003914
0.023483
0.003914
0.021526
0.023483
0.011742
0.013699
0.023483
0.04501
0.04501
0
0.011742
0.015656
0.019569
0.027397
0.062622
0.056751
0.091977
0.076321
0.02544
0.097847
0
0.041096
0.007828
0.035225
0.041096
0.113503
0.041096
0.001957
0.003914
0.005871
1
9,110
C
T
G
C
C
T
G
T
C
G
C
A
G
G
C
A
G
T
C
G
A
T
T
C
T
C
C
T
A
A
T
C
T
T
A
C
C
C
T
T
C
T
G
G
T
C
G
G
G
A
T
T
G
G
A
T
A
A
G
A
C
A
C
A
G
G
0.058708
0.019569
0.056751
0.019569
0.031311
0.019569
0.013699
0.035225
0.041096
0.039139
0.037182
0.019569
0.043053
0.031311
0.046967
0.033268
0.048924
0.035225
0.017613
0.011742
0.021526
0.015656
0.013699
0.033268
0.037182
0.02544
0.052838
0.029354
0.035225
0.021526
0.013699
0.041096
1
9,111
C
C
A
C
C
G
C
A
T
G
T
G
C
T
G
C
C
T
G
G
A
G
A
A
T
A
C
A
G
T
T
A
C
A
A
G
G
T
T
G
C
C
C
A
G
G
T
A
T
C
T
A
A
A
T
G
C
A
A
A
T
G
A
A
A
T
0.11546
0.035225
0.043053
0.037182
0.035225
0.031311
0.001957
0.037182
0.035225
0.019569
0.037182
0.043053
0.033268
0.039139
0.033268
0.029354
0.039139
0.035225
0.02544
0.001957
0.005871
0.001957
0.02544
0.021526
0.023483
0.011742
0.04501
0.019569
0.023483
0.029354
0.058708
0.02544
1
9,112
A
A
C
T
C
C
A
G
G
A
T
A
G
T
G
A
A
C
A
T
A
T
T
C
G
A
T
C
T
G
G
C
C
A
T
A
T
C
G
C
G
G
A
G
G
G
G
A
G
G
T
G
A
T
G
A
C
A
T
A
G
A
G
C
A
T
0.058708
0.035225
0.037182
0.033268
0.064579
0.029354
0.009785
0.027397
0.037182
0.019569
0.037182
0.052838
0.035225
0.046967
0.039139
0.041096
0.037182
0.041096
0.017613
0.003914
0.009785
0.007828
0.019569
0.02544
0.029354
0.027397
0.017613
0.021526
0.031311
0.027397
0.037182
0.041096
1
9,113
A
C
C
A
G
C
T
T
C
C
A
A
A
A
G
A
G
G
C
T
C
C
T
G
G
A
G
T
T
T
C
T
C
G
G
C
A
T
T
T
G
G
T
T
G
T
C
A
A
G
G
A
A
A
C
T
G
A
G
G
T
G
G
C
C
T
0.082192
0.029354
0.02544
0.068493
0.035225
0.023483
0
0.039139
0.033268
0.027397
0.029354
0.088063
0.019569
0.037182
0.043053
0.021526
0.037182
0.04501
0.007828
0.001957
0.001957
0
0.035225
0.031311
0.039139
0.021526
0.015656
0.019569
0.033268
0.02544
0.039139
0.043053
1
9,114
T
G
T
C
A
T
C
G
A
G
T
T
C
T
T
T
G
G
T
C
A
A
C
A
G
T
T
T
A
C
G
A
T
G
T
A
G
G
T
T
T
A
T
G
T
T
G
G
C
A
C
T
G
T
G
T
C
T
A
G
G
A
A
A
A
C
0.048924
0.019569
0.039139
0.031311
0.023483
0.039139
0.011742
0.029354
0.027397
0.027397
0.052838
0.031311
0.023483
0.043053
0.023483
0.039139
0.037182
0.050881
0.060665
0.005871
0.015656
0.009785
0.019569
0.041096
0.035225
0.027397
0.033268
0.019569
0.050881
0.015656
0.031311
0.035225
1
9,115
A
G
G
A
A
G
C
T
A
T
A
A
A
C
T
A
C
T
C
C
T
C
T
A
G
A
T
T
T
T
A
C
C
T
T
G
T
C
A
A
G
A
G
C
C
G
T
A
T
T
G
T
G
A
A
A
G
G
A
T
G
T
T
G
A
G
0.09002
0.04501
0.052838
0.048924
0.029354
0.035225
0.007828
0.033268
0.04501
0.02544
0.031311
0.037182
0.017613
0.033268
0.052838
0.021526
0.031311
0.037182
0.011742
0.007828
0.001957
0.005871
0.021526
0.029354
0.043053
0.013699
0.041096
0.013699
0.027397
0.027397
0.050881
0.029354
1
9,116
G
G
A
C
C
T
G
G
C
T
G
A
G
G
A
G
C
T
G
G
G
C
C
A
T
C
G
C
G
A
T
G
T
C
G
C
A
C
G
G
T
A
C
C
T
G
C
G
C
G
C
G
G
C
T
G
C
G
G
G
G
G
G
C
A
A
0.011742
0.007828
0.011742
0.011742
0.009785
0.037182
0.023483
0.015656
0.035225
0.050881
0.035225
0.003914
0.021526
0.029354
0.011742
0.035225
0.07045
0.048924
0.062622
0.060665
0.019569
0.068493
0.003914
0.050881
0.019569
0.033268
0.054795
0.072407
0.035225
0.009785
0.001957
0.035225
1
9,117
A
G
C
T
C
C
T
C
A
G
C
C
A
G
G
T
C
C
A
C
G
G
G
C
A
G
A
C
G
G
C
C
C
C
A
G
G
C
A
T
C
G
C
G
C
A
C
G
T
C
C
A
G
C
C
G
C
G
C
C
C
C
G
G
C
T
0.011742
0.007828
0.017613
0.011742
0.013699
0.039139
0.023483
0.013699
0.035225
0.056751
0.033268
0.001957
0.019569
0.033268
0.011742
0.037182
0.066536
0.046967
0.064579
0.060665
0.017613
0.062622
0.003914
0.050881
0.023483
0.031311
0.052838
0.066536
0.035225
0.011742
0.001957
0.035225
1
9,118
G
C
C
C
C
A
G
G
C
A
T
C
G
C
G
C
A
C
G
T
C
C
A
G
C
C
G
C
G
C
C
C
C
G
G
C
C
C
G
G
T
G
C
A
G
C
A
C
C
A
C
C
A
G
C
G
T
G
T
C
C
A
G
G
A
A
0.011742
0.007828
0.019569
0.009785
0.017613
0.039139
0.021526
0.013699
0.035225
0.056751
0.031311
0.001957
0.017613
0.033268
0.011742
0.041096
0.066536
0.048924
0.074364
0.058708
0.015656
0.058708
0.003914
0.046967
0.023483
0.031311
0.052838
0.066536
0.035225
0.011742
0.001957
0.033268
1
9,119
G
T
G
C
A
G
C
A
C
C
A
C
C
A
G
C
G
T
G
T
C
C
A
G
G
A
A
G
C
C
C
T
C
C
C
G
G
G
C
A
G
C
G
T
C
G
T
G
C
A
C
G
G
G
T
C
G
G
G
T
G
A
G
A
G
A
0.009785
0.007828
0.019569
0.015656
0.019569
0.041096
0.021526
0.011742
0.031311
0.054795
0.035225
0.001957
0.017613
0.035225
0.015656
0.041096
0.062622
0.050881
0.074364
0.052838
0.015656
0.058708
0.007828
0.043053
0.021526
0.029354
0.052838
0.064579
0.033268
0.015656
0.005871
0.031311
1
9,120
G
C
C
G
A
C
C
C
C
G
C
C
A
C
T
C
T
C
A
C
C
C
G
A
C
C
C
G
T
G
C
A
C
G
A
C
G
C
T
G
C
C
C
G
G
G
A
G
G
G
C
T
T
C
C
T
G
G
A
C
A
C
G
C
T
G
0.011742
0.007828
0.023483
0.015656
0.019569
0.041096
0.021526
0.011742
0.031311
0.052838
0.037182
0.001957
0.017613
0.031311
0.017613
0.041096
0.060665
0.050881
0.074364
0.052838
0.015656
0.058708
0.007828
0.041096
0.023483
0.029354
0.050881
0.064579
0.035225
0.015656
0.005871
0.029354
1
9,121
G
C
G
T
G
T
C
C
A
G
G
A
A
G
C
C
C
T
C
C
C
G
G
G
C
A
G
C
G
T
C
G
T
G
C
A
C
G
G
G
T
C
G
G
G
T
G
A
G
A
G
T
G
G
C
G
G
G
G
T
C
G
G
C
G
A
0.011742
0.007828
0.023483
0.015656
0.019569
0.041096
0.021526
0.013699
0.031311
0.050881
0.037182
0.001957
0.017613
0.031311
0.017613
0.041096
0.060665
0.050881
0.074364
0.052838
0.015656
0.058708
0.007828
0.041096
0.023483
0.029354
0.050881
0.064579
0.035225
0.015656
0.005871
0.029354
1
9,122
C
T
C
T
C
T
G
G
C
A
G
G
T
C
A
T
G
A
T
G
A
T
G
G
G
C
A
G
C
G
C
C
C
G
A
G
T
G
G
C
G
G
A
G
C
T
G
C
T
G
C
T
G
C
T
C
C
A
C
G
G
C
G
C
G
T
0.007828
0.011742
0.021526
0.021526
0.02544
0.035225
0.023483
0.015656
0.033268
0.048924
0.031311
0.007828
0.013699
0.031311
0.015656
0.043053
0.062622
0.052838
0.068493
0.050881
0.019569
0.054795
0.007828
0.037182
0.031311
0.029354
0.050881
0.062622
0.037182
0.015656
0.007828
0.023483
1
9,123
A
G
C
A
G
C
A
G
C
T
C
C
G
C
C
A
C
T
C
G
G
G
C
G
C
T
G
C
C
C
A
T
C
A
T
C
A
T
G
A
C
C
T
G
C
C
A
G
A
G
A
G
A
A
C
A
G
A
A
T
G
G
T
C
A
G
0.007828
0.009785
0.021526
0.021526
0.027397
0.033268
0.023483
0.015656
0.035225
0.050881
0.031311
0.007828
0.013699
0.027397
0.015656
0.046967
0.062622
0.050881
0.068493
0.050881
0.019569
0.054795
0.007828
0.043053
0.031311
0.029354
0.048924
0.060665
0.037182
0.013699
0.005871
0.02544
1
9,124
C
C
A
C
T
T
T
T
A
G
A
C
T
T
C
T
T
G
T
G
G
C
T
C
T
T
G
G
A
A
C
A
C
T
T
A
T
C
A
G
T
G
A
T
G
A
T
T
C
A
A
A
T
G
C
T
G
T
A
C
A
A
T
T
A
T
0.084149
0.027397
0.043053
0.068493
0.050881
0.009785
0.003914
0.039139
0.041096
0.027397
0.023483
0.029354
0.035225
0.039139
0.048924
0.027397
0.037182
0.031311
0.019569
0.003914
0
0
0.031311
0.019569
0.043053
0.021526
0.019569
0.019569
0.029354
0.027397
0.048924
0.048924
1
9,125
T
C
T
C
C
C
C
A
T
C
T
C
T
G
A
T
T
A
G
A
C
G
A
G
T
C
T
G
T
C
C
T
T
C
T
C
T
A
G
T
A
C
C
T
T
A
A
A
A
T
A
A
A
A
A
T
T
T
T
A
A
G
A
A
T
A
0.1409
0.031311
0.046967
0.086106
0.037182
0.013699
0.005871
0.029354
0.041096
0.009785
0.029354
0.04501
0.031311
0.031311
0.041096
0.019569
0.015656
0.027397
0.013699
0
0.009785
0
0.031311
0.015656
0.04501
0.015656
0.011742
0.017613
0.02544
0.019569
0.080235
0.031311
1
9,126
C
T
A
T
C
C
G
A
C
T
T
C
C
A
G
C
T
C
A
G
T
C
T
A
T
A
T
G
G
T
G
C
T
G
C
T
G
T
G
T
G
C
T
C
G
A
C
A
A
T
G
G
T
G
A
C
A
T
T
G
T
G
G
T
T
C
0.060665
0.027397
0.031311
0.062622
0.056751
0.015656
0.003914
0.052838
0.039139
0.019569
0.017613
0.076321
0.023483
0.046967
0.041096
0.029354
0.035225
0.023483
0.007828
0.001957
0.007828
0.001957
0.039139
0.023483
0.037182
0.031311
0.027397
0.005871
0.021526
0.041096
0.043053
0.046967
1
9,127
C
C
G
C
C
G
G
G
A
G
C
C
T
T
T
G
T
G
T
C
C
G
T
G
T
C
C
C
G
A
G
A
C
C
G
C
A
C
C
A
C
C
C
G
C
C
T
C
T
G
G
G
C
C
C
C
A
G
A
C
A
G
G
T
G
G
0.009785
0.013699
0.027397
0.007828
0.029354
0.035225
0.015656
0.021526
0.052838
0.04501
0.041096
0.003914
0.005871
0.005871
0.017613
0.037182
0.056751
0.039139
0.072407
0.07045
0.019569
0.046967
0.007828
0.068493
0.021526
0.039139
0.037182
0.064579
0.050881
0.011742
0.011742
0.011742
1
9,128
A
G
G
C
T
C
C
C
G
G
C
G
G
A
T
A
G
G
C
G
C
A
G
C
A
C
A
C
C
A
G
G
C
C
C
C
G
T
A
C
G
T
C
C
A
G
C
T
C
G
T
G
G
C
C
C
C
G
G
A
G
C
G
A
G
A
0.005871
0.009785
0.023483
0.007828
0.027397
0.031311
0.017613
0.021526
0.048924
0.04501
0.039139
0.003914
0.005871
0.005871
0.009785
0.035225
0.054795
0.035225
0.074364
0.084149
0.023483
0.058708
0.005871
0.07045
0.023483
0.037182
0.031311
0.076321
0.050881
0.015656
0.005871
0.013699
1
9,129
C
C
C
A
A
G
T
G
T
C
A
T
A
C
T
T
A
T
C
T
T
A
A
A
A
T
A
G
G
T
A
C
C
T
T
T
C
G
T
C
C
C
A
G
T
T
T
T
C
A
T
T
C
C
A
G
T
C
A
A
A
C
C
T
T
T
0.127202
0.043053
0.035225
0.076321
0.062622
0.021526
0.005871
0.035225
0.035225
0.003914
0.017613
0.041096
0.027397
0.039139
0.050881
0.021526
0.033268
0.031311
0.013699
0
0.007828
0.001957
0.013699
0.009785
0.037182
0.019569
0.015656
0.013699
0.013699
0.041096
0.068493
0.035225
1
9,130
T
T
C
T
T
A
A
G
G
C
G
C
G
C
A
T
C
A
A
G
A
A
G
G
A
T
G
G
G
T
T
A
C
G
G
A
T
G
G
A
T
G
C
T
G
C
C
A
T
C
A
A
A
A
G
A
A
T
G
A
A
A
G
G
T
T
0.066536
0.031311
0.043053
0.054795
0.033268
0.023483
0.003914
0.02544
0.037182
0.021526
0.041096
0.029354
0.043053
0.046967
0.054795
0.019569
0.046967
0.043053
0.023483
0.001957
0
0.009785
0.013699
0.021526
0.04501
0.02544
0.031311
0.02544
0.037182
0.009785
0.029354
0.060665
1
9,131
A
T
G
A
G
T
C
G
A
T
G
C
T
C
T
C
T
T
C
C
T
T
C
C
C
T
C
C
A
G
G
C
T
A
C
T
T
G
T
A
C
C
T
G
G
C
C
A
T
T
G
A
G
T
A
C
G
C
G
C
C
C
C
A
T
C
0.046967
0.023483
0.037182
0.021526
0.035225
0.02544
0.015656
0.033268
0.02544
0.039139
0.048924
0.017613
0.011742
0.031311
0.039139
0.041096
0.04501
0.054795
0.04501
0.017613
0.011742
0.017613
0.019569
0.04501
0.033268
0.031311
0.041096
0.035225
0.060665
0.015656
0.009785
0.023483
1
9,132
C
A
T
G
G
G
G
C
G
C
G
T
A
C
T
C
A
A
T
G
G
C
C
A
G
G
T
A
C
A
A
G
T
A
G
C
C
T
G
G
A
G
G
G
A
A
G
G
A
A
G
A
G
A
G
C
A
T
C
G
A
C
T
C
A
C
0.046967
0.023483
0.037182
0.021526
0.037182
0.02544
0.015656
0.033268
0.02544
0.039139
0.048924
0.017613
0.011742
0.031311
0.039139
0.039139
0.04501
0.054795
0.04501
0.017613
0.011742
0.017613
0.019569
0.04501
0.033268
0.031311
0.041096
0.035225
0.060665
0.015656
0.009785
0.023483
1
9,133
A
G
T
A
C
G
C
G
C
C
C
C
A
T
G
G
A
A
A
C
C
T
T
C
T
G
G
A
C
T
T
C
C
T
T
C
G
C
A
A
G
A
G
C
C
G
T
G
T
G
C
T
G
G
A
G
A
C
G
G
A
C
C
C
A
T
0.048924
0.02544
0.043053
0.021526
0.039139
0.021526
0.015656
0.033268
0.035225
0.037182
0.048924
0.017613
0.013699
0.029354
0.039139
0.033268
0.04501
0.046967
0.041096
0.017613
0.011742
0.017613
0.019569
0.04501
0.033268
0.035225
0.035225
0.035225
0.056751
0.015656
0.017613
0.023483
1
9,134
A
C
G
C
G
C
C
C
C
A
T
G
G
A
A
A
C
C
T
T
C
T
G
G
A
C
T
T
C
C
T
T
C
G
C
A
A
G
A
G
C
C
G
T
G
T
G
C
T
G
G
A
G
A
C
G
G
A
C
C
C
A
G
C
A
T
0.048924
0.02544
0.041096
0.021526
0.039139
0.021526
0.015656
0.033268
0.035225
0.035225
0.048924
0.017613
0.013699
0.031311
0.037182
0.033268
0.04501
0.046967
0.041096
0.017613
0.011742
0.017613
0.019569
0.046967
0.033268
0.035225
0.035225
0.035225
0.056751
0.015656
0.017613
0.02544
1
9,135
A
T
G
C
T
G
G
G
T
C
C
G
T
C
T
C
C
A
G
C
A
C
A
C
G
G
C
T
C
T
T
G
C
G
A
A
G
G
A
A
G
T
C
C
A
G
A
A
G
G
T
T
T
C
C
A
T
G
G
G
G
C
G
C
G
T
0.048924
0.02544
0.041096
0.023483
0.039139
0.021526
0.015656
0.033268
0.035225
0.035225
0.048924
0.017613
0.013699
0.031311
0.037182
0.033268
0.04501
0.046967
0.041096
0.017613
0.011742
0.015656
0.019569
0.046967
0.033268
0.035225
0.035225
0.035225
0.056751
0.015656
0.017613
0.02544
1
9,136
T
G
T
A
C
G
G
G
T
G
T
T
G
T
T
T
A
C
T
A
G
T
G
T
T
G
T
G
G
C
A
T
T
C
A
T
C
A
A
A
T
A
T
C
A
T
C
A
A
A
G
T
A
A
A
G
A
T
G
G
A
T
A
G
T
G
0.048924
0.043053
0.039139
0.052838
0.050881
0.013699
0.007828
0.037182
0.048924
0.013699
0.02544
0.039139
0.054795
0.052838
0.039139
0.027397
0.037182
0.039139
0.015656
0.001957
0.005871
0
0.02544
0.023483
0.054795
0.015656
0.011742
0.013699
0.039139
0.023483
0.043053
0.054795
1
9,137
C
A
C
A
T
A
T
A
A
G
C
A
G
T
G
A
A
A
C
A
A
A
G
G
T
T
T
T
T
C
C
A
C
A
A
C
C
T
T
T
T
A
A
C
A
T
G
T
A
A
G
G
A
A
A
A
A
A
G
A
A
A
A
C
A
A
0.135029
0.033268
0.054795
0.060665
0.052838
0.017613
0
0.02544
0.041096
0.031311
0.023483
0.050881
0.02544
0.043053
0.039139
0.019569
0.029354
0.021526
0.013699
0
0.001957
0.001957
0.021526
0.017613
0.048924
0.015656
0.015656
0.005871
0.021526
0.027397
0.060665
0.043053
1
9,138
T
T
T
T
C
T
T
T
C
A
A
C
T
A
G
C
C
A
T
G
T
A
C
A
T
C
T
T
C
A
T
G
T
G
A
T
C
A
G
C
C
A
G
G
A
T
T
T
T
G
A
T
T
C
T
C
C
T
T
G
C
C
T
T
A
G
0.093933
0.041096
0.041096
0.074364
0.056751
0.009785
0
0.04501
0.029354
0.019569
0.023483
0.056751
0.023483
0.043053
0.054795
0.021526
0.029354
0.023483
0.005871
0
0.001957
0.001957
0.02544
0.021526
0.058708
0.009785
0.007828
0.015656
0.021526
0.039139
0.043053
0.060665
1
9,139
G
T
C
T
G
A
A
G
G
C
T
G
T
G
G
C
C
A
G
G
G
A
A
C
A
C
C
T
T
G
A
A
C
T
C
C
T
T
A
A
G
C
A
T
A
T
G
C
A
C
A
C
T
G
T
G
G
G
G
G
A
A
A
A
G
T
0.041096
0.023483
0.04501
0.029354
0.031311
0.04501
0.005871
0.029354
0.041096
0.041096
0.043053
0.027397
0.023483
0.021526
0.031311
0.048924
0.056751
0.066536
0.037182
0.009785
0.003914
0.003914
0.019569
0.033268
0.037182
0.017613
0.035225
0.033268
0.041096
0.021526
0.029354
0.02544
1
9,140
C
C
C
A
A
A
G
G
C
C
C
G
T
T
A
C
C
A
T
T
G
G
C
T
G
G
T
C
T
T
A
C
C
G
T
G
G
A
C
C
T
C
C
A
T
T
T
C
C
A
G
T
C
T
G
A
A
G
G
C
T
G
T
G
G
T
0.035225
0.02544
0.041096
0.033268
0.037182
0.043053
0.005871
0.033268
0.043053
0.035225
0.043053
0.029354
0.021526
0.021526
0.035225
0.048924
0.058708
0.056751
0.033268
0.009785
0.003914
0.003914
0.021526
0.033268
0.035225
0.023483
0.039139
0.031311
0.035225
0.021526
0.029354
0.031311
1
9,141
T
G
G
A
A
A
T
G
G
A
G
G
T
C
C
A
C
G
G
T
A
A
G
A
C
C
A
G
C
C
A
A
T
G
G
T
A
A
C
G
G
G
C
C
T
T
T
G
G
G
T
A
T
T
T
A
T
C
C
T
T
T
A
T
C
C
0.037182
0.02544
0.043053
0.035225
0.037182
0.041096
0.005871
0.031311
0.04501
0.035225
0.04501
0.029354
0.023483
0.021526
0.035225
0.046967
0.054795
0.054795
0.031311
0.009785
0.003914
0.003914
0.023483
0.033268
0.037182
0.021526
0.037182
0.031311
0.037182
0.021526
0.031311
0.029354
1
9,142
G
T
A
T
G
A
A
T
A
A
A
C
A
A
A
G
A
A
T
G
C
A
C
C
T
C
T
G
A
G
G
A
T
T
G
G
G
T
T
C
A
T
T
T
T
T
C
T
T
G
T
C
T
C
T
T
G
A
G
T
G
G
C
G
G
C
0.048924
0.02544
0.039139
0.029354
0.039139
0.035225
0.003914
0.023483
0.052838
0.029354
0.050881
0.013699
0.029354
0.041096
0.041096
0.039139
0.041096
0.037182
0.035225
0.011742
0.009785
0.005871
0.015656
0.060665
0.029354
0.023483
0.041096
0.029354
0.035225
0.015656
0.021526
0.04501
1
9,143
C
T
G
T
G
T
C
T
C
T
T
C
G
C
C
A
T
C
A
C
G
G
A
C
C
A
G
G
A
G
A
A
C
A
A
C
C
C
A
G
C
A
C
T
G
C
C
A
G
G
A
A
C
A
G
A
G
G
C
G
C
T
G
G
T
A
0.009785
0.019569
0.017613
0.003914
0.039139
0.041096
0.013699
0.015656
0.031311
0.033268
0.066536
0.009785
0.029354
0.031311
0.021526
0.04501
0.074364
0.054795
0.09589
0.02544
0.009785
0.009785
0.003914
0.050881
0.019569
0.035225
0.043053
0.046967
0.056751
0.009785
0
0.035225
1
9,144
T
G
T
G
T
T
C
A
G
T
G
G
C
C
A
C
G
T
G
G
C
T
T
G
G
T
G
A
G
A
T
G
T
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G
G
C
G
A
T
C
A
T
G
C
A
G
G
T
T
T
T
G
G
C
A
T
T
G
C
C
G
A
T
G
C
0.052838
0.027397
0.037182
0.031311
0.078278
0.027397
0.011742
0.037182
0.027397
0.019569
0.031311
0.011742
0.019569
0.054795
0.046967
0.082192
0.039139
0.039139
0.009785
0.005871
0.003914
0.017613
0.015656
0.023483
0.021526
0.029354
0.062622
0.029354
0.019569
0.017613
0.02544
0.043053
1
9,145
G
C
A
G
A
A
G
G
A
T
G
A
C
A
T
G
G
A
C
C
A
A
A
A
C
C
T
T
A
A
C
T
T
C
T
T
C
T
C
T
G
T
G
T
C
A
T
C
T
G
A
C
G
G
C
A
G
G
A
T
T
G
T
G
T
A
0.029354
0.019569
0.046967
0.021526
0.033268
0.029354
0.009785
0.015656
0.056751
0.041096
0.050881
0.003914
0.031311
0.041096
0.033268
0.039139
0.050881
0.058708
0.076321
0.003914
0.001957
0
0.015656
0.050881
0.04501
0.027397
0.029354
0.031311
0.050881
0.001957
0.009785
0.043053
1
9,146
G
G
T
C
C
C
A
G
A
T
C
T
T
C
A
C
T
G
T
C
C
A
G
T
C
G
G
A
G
C
T
G
C
A
G
G
A
C
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A
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C
C
T
T
G
G
T
G
T
G
G
T
A
T
G
G
G
T
T
C
T
0.005871
0.017613
0.027397
0.005871
0.041096
0.039139
0.007828
0.033268
0.033268
0.037182
0.056751
0.009785
0.023483
0.035225
0.009785
0.056751
0.076321
0.072407
0.066536
0.009785
0.013699
0.011742
0.013699
0.041096
0.033268
0.039139
0.027397
0.048924
0.052838
0.007828
0.007828
0.037182
1
9,147
G
C
C
C
A
A
G
G
C
G
G
T
G
C
C
G
A
A
G
A
G
C
A
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C
A
C
A
T
A
C
T
C
G
G
A
C
A
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C
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A
G
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C
G
T
G
C
A
G
A
A
G
G
C
A
C
A
T
G
G
C
G
C
G
0.009785
0.007828
0.017613
0.007828
0.017613
0.033268
0.015656
0.021526
0.027397
0.046967
0.046967
0.007828
0.023483
0.031311
0.011742
0.048924
0.058708
0.064579
0.060665
0.048924
0.027397
0.048924
0.015656
0.050881
0.019569
0.021526
0.04501
0.09002
0.039139
0.009785
0.001957
0.021526
1
9,148
G
C
G
T
T
G
C
T
G
A
G
G
A
T
C
G
G
T
T
C
C
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G
A
T
C
C
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C
T
G
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A
A
A
A
T
C
T
G
C
C
0.015656
0.019569
0.02544
0.011742
0.019569
0.027397
0.023483
0.02544
0.019569
0.050881
0.052838
0
0.023483
0.011742
0.019569
0.033268
0.074364
0.04501
0.066536
0.046967
0.021526
0.048924
0.011742
0.035225
0.033268
0.027397
0.041096
0.07045
0.046967
0.015656
0.003914
0.031311
1
9,149
C
A
G
A
T
T
T
T
C
C
A
G
C
G
G
A
T
C
C
C
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A
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G
A
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T
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C
A
A
C
G
C
C
G
0.015656
0.019569
0.02544
0.011742
0.019569
0.027397
0.023483
0.02544
0.019569
0.050881
0.052838
0
0.023483
0.011742
0.019569
0.033268
0.074364
0.04501
0.066536
0.046967
0.021526
0.048924
0.011742
0.035225
0.033268
0.027397
0.041096
0.07045
0.046967
0.015656
0.003914
0.031311
1
9,150
T
G
C
G
G
T
G
A
G
C
T
G
A
C
A
C
C
A
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C
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A
G
C
G
G
A
T
A
T
G
C
T
G
A
T
G
G
T
C
T
G
0.001957
0.015656
0.027397
0.005871
0.02544
0.035225
0.009785
0.021526
0.04501
0.062622
0.056751
0.009785
0.021526
0.021526
0.023483
0.027397
0.076321
0.056751
0.068493
0.02544
0.013699
0.023483
0.017613
0.064579
0.019569
0.033268
0.033268
0.056751
0.046967
0.015656
0.003914
0.033268
1
9,151
C
T
T
C
A
T
G
C
G
G
T
G
A
G
C
T
G
A
C
A
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G
T
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G
T
A
G
C
G
G
A
T
A
T
G
C
T
G
A
T
T
0.007828
0.015656
0.02544
0.005871
0.02544
0.033268
0.009785
0.021526
0.04501
0.062622
0.054795
0.009785
0.021526
0.021526
0.02544
0.027397
0.076321
0.058708
0.068493
0.02544
0.011742
0.023483
0.017613
0.064579
0.017613
0.033268
0.033268
0.056751
0.046967
0.015656
0.003914
0.033268
1
9,152
C
T
G
C
C
A
G
G
G
C
C
G
C
T
T
C
A
T
G
C
G
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A
T
C
C
T
G
C
A
G
C
G
G
G
T
T
G
T
A
G
C
T
0.007828
0.011742
0.02544
0.005871
0.02544
0.037182
0.007828
0.021526
0.04501
0.060665
0.058708
0.009785
0.021526
0.019569
0.023483
0.029354
0.076321
0.056751
0.074364
0.02544
0.011742
0.021526
0.021526
0.062622
0.015656
0.035225
0.033268
0.056751
0.046967
0.015656
0.003914
0.031311
1
9,153
T
G
C
A
G
G
A
T
G
A
G
T
G
G
G
T
G
C
T
G
G
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C
C
T
G
G
C
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G
T
C
A
A
G
T
G
G
A
G
A
0.007828
0.011742
0.027397
0.005871
0.02544
0.037182
0.007828
0.021526
0.043053
0.058708
0.062622
0.009785
0.019569
0.019569
0.023483
0.029354
0.074364
0.056751
0.076321
0.023483
0.009785
0.021526
0.023483
0.060665
0.017613
0.033268
0.033268
0.058708
0.046967
0.017613
0.003914
0.031311
1
9,154
A
A
G
T
G
G
A
G
C
C
C
C
A
G
C
T
T
C
T
G
A
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T
C
A
A
C
C
C
T
C
T
G
T
G
T
C
C
T
G
G
G
T
0.009785
0.013699
0.031311
0.001957
0.023483
0.043053
0.003914
0.02544
0.043053
0.056751
0.060665
0.011742
0.019569
0.021526
0.021526
0.033268
0.07045
0.062622
0.082192
0.021526
0.005871
0.015656
0.02544
0.060665
0.017613
0.033268
0.027397
0.052838
0.048924
0.015656
0.005871
0.033268
1
9,155
T
A
G
C
C
T
A
T
C
C
T
T
G
T
C
G
G
T
A
G
G
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T
C
C
T
G
T
T
T
G
A
C
A
A
C
G
A
C
T
T
C
G
0.023483
0.02544
0.041096
0.003914
0.017613
0.043053
0.007828
0.04501
0.037182
0.041096
0.066536
0.015656
0.023483
0.013699
0.029354
0.029354
0.066536
0.058708
0.064579
0.005871
0.009785
0
0.031311
0.050881
0.027397
0.029354
0.035225
0.029354
0.056751
0.029354
0.013699
0.027397
1
9,156
T
A
A
G
A
G
G
G
G
A
A
A
T
C
C
A
T
A
G
T
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C
T
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G
G
A
A
A
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G
G
G
A
T
G
A
T
C
A
T
0.019569
0.027397
0.031311
0.005871
0.021526
0.048924
0.009785
0.041096
0.033268
0.043053
0.052838
0.011742
0.027397
0.02544
0.027397
0.031311
0.066536
0.052838
0.062622
0.017613
0.017613
0.001957
0.019569
0.050881
0.021526
0.031311
0.041096
0.031311
0.04501
0.031311
0.015656
0.035225
1
9,157
A
T
C
T
T
T
T
C
T
C
C
C
G
T
C
A
C
C
A
C
C
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C
T
G
G
T
C
G
G
A
T
G
T
A
A
C
G
C
T
G
C
C
0.029354
0.029354
0.035225
0.005871
0.029354
0.048924
0.005871
0.033268
0.037182
0.039139
0.054795
0.005871
0.023483
0.027397
0.031311
0.035225
0.058708
0.052838
0.074364
0.015656
0.013699
0.003914
0.011742
0.058708
0.023483
0.031311
0.035225
0.027397
0.046967
0.021526
0.015656
0.037182
1
9,158
C
C
A
C
C
C
C
T
G
G
T
C
G
G
A
T
G
T
A
A
C
G
C
T
G
C
C
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C
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C
A
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G
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C
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G
A
T
C
C
G
G
G
C
T
G
T
T
G
T
T
G
A
T
G
A
0.037182
0.031311
0.035225
0.005871
0.031311
0.046967
0.007828
0.031311
0.039139
0.033268
0.050881
0.011742
0.033268
0.027397
0.033268
0.035225
0.056751
0.048924
0.068493
0.017613
0.013699
0.003914
0.011742
0.050881
0.02544
0.027397
0.033268
0.027397
0.04501
0.023483
0.015656
0.039139
1
9,159
C
C
A
C
C
C
C
T
G
G
T
C
G
G
A
T
G
T
A
A
C
G
C
T
G
C
C
A
C
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C
A
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G
G
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C
C
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A
G
A
T
C
C
G
G
G
C
T
G
T
T
G
T
T
G
A
T
G
C
0.037182
0.031311
0.035225
0.005871
0.031311
0.046967
0.007828
0.031311
0.039139
0.033268
0.050881
0.011742
0.033268
0.027397
0.033268
0.035225
0.056751
0.048924
0.068493
0.017613
0.013699
0.003914
0.011742
0.050881
0.02544
0.027397
0.033268
0.027397
0.04501
0.023483
0.015656
0.039139
1
9,160
C
C
C
C
T
G
G
T
C
G
G
A
T
G
T
A
A
C
G
C
T
G
C
C
A
C
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C
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C
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G
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C
C
G
G
G
C
T
G
T
T
G
T
T
G
A
T
G
C
A
T
G
0.037182
0.031311
0.035225
0.005871
0.031311
0.046967
0.007828
0.031311
0.037182
0.033268
0.050881
0.011742
0.033268
0.031311
0.033268
0.035225
0.054795
0.050881
0.068493
0.017613
0.013699
0.003914
0.011742
0.050881
0.023483
0.027397
0.033268
0.027397
0.04501
0.023483
0.015656
0.039139
1
9,161
T
A
A
C
G
C
T
G
C
C
A
C
T
C
A
T
G
T
C
G
G
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A
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C
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A
T
G
C
A
T
G
G
G
C
C
T
C
A
G
T
C
A
C
A
T
0.037182
0.033268
0.035225
0.005871
0.033268
0.046967
0.007828
0.029354
0.035225
0.033268
0.050881
0.011742
0.033268
0.033268
0.033268
0.033268
0.052838
0.052838
0.07045
0.017613
0.013699
0.003914
0.013699
0.046967
0.02544
0.027397
0.027397
0.029354
0.04501
0.023483
0.017613
0.039139
1
9,162
G
G
G
G
G
T
G
G
G
G
G
T
T
A
G
A
A
C
A
G
C
C
C
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A
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C
A
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C
A
A
A
G
A
T
C
T
A
T
C
A
G
A
T
A
G
G
G
A
T
A
T
0.031311
0.029354
0.029354
0.011742
0.041096
0.039139
0.003914
0.019569
0.035225
0.035225
0.056751
0.015656
0.033268
0.037182
0.031311
0.035225
0.07045
0.062622
0.074364
0.007828
0.005871
0.005871
0.007828
0.043053
0.02544
0.02544
0.031311
0.041096
0.046967
0.013699
0.013699
0.039139
1
9,163
T
A
T
C
T
G
A
T
A
G
A
T
C
T
T
T
G
A
A
A
A
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G
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C
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C
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T
A
A
C
C
C
C
C
A
C
C
C
C
C
A
C
T
G
C
C
C
0.031311
0.029354
0.029354
0.011742
0.039139
0.039139
0.003914
0.019569
0.035225
0.037182
0.058708
0.015656
0.033268
0.033268
0.031311
0.035225
0.072407
0.062622
0.074364
0.007828
0.005871
0.005871
0.007828
0.041096
0.02544
0.023483
0.033268
0.04501
0.046967
0.013699
0.013699
0.037182
1
9,164
A
A
G
G
T
G
C
C
A
T
G
A
T
G
G
G
C
T
G
T
T
C
T
A
A
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C
C
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C
A
C
C
C
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C
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T
G
C
C
A
G
G
T
A
A
G
G
G
T
G
T
C
A
G
G
G
G
C
T
C
C
A
T
0.031311
0.027397
0.031311
0.011742
0.037182
0.037182
0.003914
0.021526
0.037182
0.039139
0.058708
0.019569
0.029354
0.037182
0.029354
0.035225
0.07045
0.064579
0.07045
0.001957
0.003914
0.005871
0.009785
0.04501
0.02544
0.023483
0.035225
0.04501
0.04501
0.013699
0.015656
0.037182
1
9,165
G
C
C
A
T
G
A
T
G
G
G
C
T
G
T
T
C
T
A
A
C
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C
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C
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G
C
C
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T
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G
T
G
T
C
A
G
G
G
G
C
T
C
C
A
G
T
G
G
G
G
0.031311
0.02544
0.031311
0.011742
0.035225
0.037182
0.003914
0.021526
0.037182
0.039139
0.060665
0.019569
0.027397
0.037182
0.027397
0.035225
0.072407
0.064579
0.074364
0.001957
0.003914
0.005871
0.009785
0.04501
0.02544
0.023483
0.037182
0.04501
0.04501
0.013699
0.015656
0.035225
1
9,166
C
C
T
C
A
C
G
C
T
G
G
G
C
A
A
T
A
T
C
T
G
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T
C
A
A
G
G
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C
A
A
A
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G
C
A
G
A
G
T
0.027397
0.017613
0.039139
0.017613
0.031311
0.023483
0.003914
0.027397
0.052838
0.048924
0.062622
0.023483
0.029354
0.031311
0.023483
0.027397
0.060665
0.054795
0.050881
0.003914
0.001957
0.005871
0.031311
0.060665
0.023483
0.019569
0.029354
0.04501
0.050881
0.019569
0.027397
0.027397
1
9,167
C
T
T
T
T
G
C
C
C
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A
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T
G
C
C
C
A
G
C
G
T
G
A
G
G
A
G
C
G
A
C
0.029354
0.017613
0.041096
0.017613
0.029354
0.023483
0.003914
0.027397
0.052838
0.046967
0.062622
0.023483
0.029354
0.031311
0.023483
0.027397
0.058708
0.054795
0.050881
0.003914
0.001957
0.005871
0.031311
0.058708
0.02544
0.019569
0.029354
0.04501
0.052838
0.019569
0.027397
0.027397
1
9,168
T
G
C
C
C
C
T
T
G
A
C
A
G
G
T
A
T
G
G
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C
G
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G
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G
C
G
A
T
C
T
C
C
0.029354
0.017613
0.041096
0.017613
0.029354
0.023483
0.003914
0.027397
0.052838
0.04501
0.062622
0.023483
0.033268
0.033268
0.023483
0.027397
0.058708
0.054795
0.050881
0.001957
0.001957
0.005871
0.031311
0.056751
0.02544
0.019569
0.029354
0.04501
0.050881
0.019569
0.027397
0.029354
1
9,169
G
A
C
T
C
T
T
A
T
A
G
G
C
C
T
G
C
T
G
A
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T
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G
C
A
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A
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T
G
C
T
G
G
C
C
T
0.029354
0.017613
0.043053
0.017613
0.029354
0.027397
0.001957
0.031311
0.050881
0.04501
0.060665
0.017613
0.02544
0.035225
0.023483
0.029354
0.056751
0.056751
0.050881
0.003914
0.003914
0.005871
0.029354
0.058708
0.02544
0.023483
0.029354
0.04501
0.048924
0.017613
0.029354
0.029354
1
9,170
C
C
A
T
T
A
G
C
A
G
G
G
G
C
T
C
T
C
C
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A
T
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G
C
T
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C
T
C
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C
G
C
T
G
G
G
C
A
G
0.021526
0.017613
0.039139
0.017613
0.027397
0.033268
0.001957
0.033268
0.052838
0.04501
0.060665
0.017613
0.021526
0.031311
0.019569
0.035225
0.056751
0.060665
0.050881
0.003914
0.003914
0.005871
0.033268
0.062622
0.02544
0.023483
0.027397
0.043053
0.048924
0.019569
0.031311
0.027397
1
9,171
G
G
T
T
A
G
T
A
C
T
G
G
T
C
C
C
C
T
T
C
T
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T
G
C
T
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C
T
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C
C
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G
T
C
G
G
C
A
T
A
0.013699
0.013699
0.039139
0.013699
0.017613
0.041096
0.011742
0.035225
0.048924
0.041096
0.056751
0.009785
0.035225
0.039139
0.021526
0.029354
0.060665
0.056751
0.039139
0.013699
0.003914
0.005871
0.043053
0.039139
0.029354
0.043053
0.031311
0.037182
0.048924
0.019569
0.015656
0.04501
1
9,172
C
C
A
G
G
A
T
C
C
T
A
C
T
T
G
G
G
A
G
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G
C
T
C
A
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G
T
A
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C
C
G
C
C
G
C
A
C
G
0.017613
0.013699
0.035225
0.011742
0.019569
0.041096
0.011742
0.031311
0.04501
0.048924
0.054795
0.013699
0.027397
0.041096
0.023483
0.029354
0.064579
0.060665
0.046967
0.011742
0.001957
0.005871
0.039139
0.041096
0.031311
0.039139
0.031311
0.041096
0.04501
0.021526
0.005871
0.046967
1
9,173
T
A
G
G
G
A
A
A
G
G
A
C
G
T
C
T
C
A
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T
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T
T
C
A
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A
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G
A
G
G
C
T
A
G
A
0.021526
0.023483
0.033268
0.009785
0.015656
0.035225
0.007828
0.041096
0.039139
0.060665
0.046967
0.007828
0.023483
0.037182
0.033268
0.02544
0.07045
0.064579
0.052838
0.007828
0.001957
0.005871
0.033268
0.050881
0.023483
0.027397
0.041096
0.04501
0.039139
0.023483
0.005871
0.04501
1
9,174
G
A
C
C
A
A
G
T
A
T
G
A
C
A
A
C
C
T
C
T
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G
G
G
C
T
G
G
C
A
T
G
G
T
G
A
G
G
C
T
T
A
0.021526
0.019569
0.035225
0.009785
0.017613
0.029354
0.007828
0.033268
0.043053
0.060665
0.050881
0.007828
0.029354
0.039139
0.035225
0.021526
0.068493
0.060665
0.058708
0.007828
0.001957
0.005871
0.031311
0.052838
0.02544
0.02544
0.041096
0.04501
0.04501
0.019569
0.003914
0.04501
1
9,175
A
T
A
G
G
T
A
C
T
T
G
A
A
A
A
G
C
C
T
C
A
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A
A
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G
A
C
G
T
C
T
C
A
A
A
G
A
G
G
T
T
T
0.02544
0.021526
0.033268
0.009785
0.017613
0.029354
0.007828
0.035225
0.043053
0.060665
0.048924
0.009785
0.031311
0.039139
0.033268
0.021526
0.068493
0.058708
0.052838
0.007828
0.001957
0.005871
0.033268
0.052838
0.02544
0.02544
0.039139
0.043053
0.043053
0.023483
0.003914
0.046967
1
9,176
A
C
T
A
C
C
C
T
C
C
G
C
T
C
C
T
G
C
G
C
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T
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G
G
C
T
A
C
G
A
A
A
T
G
C
T
T
G
C
T
G
0.02544
0.02544
0.027397
0.015656
0.029354
0.02544
0.005871
0.033268
0.058708
0.04501
0.062622
0.009785
0.023483
0.02544
0.02544
0.023483
0.082192
0.046967
0.046967
0.005871
0.001957
0.009785
0.019569
0.068493
0.029354
0.023483
0.048924
0.037182
0.052838
0.021526
0.011742
0.031311
1
9,177
C
C
T
G
A
G
C
A
A
G
C
A
T
T
T
C
G
T
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G
C
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C
A
G
A
G
C
G
C
A
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G
A
G
C
G
G
A
G
G
G
C
0.023483
0.023483
0.029354
0.015656
0.029354
0.02544
0.005871
0.031311
0.058708
0.04501
0.064579
0.009785
0.023483
0.02544
0.02544
0.023483
0.082192
0.046967
0.046967
0.005871
0.001957
0.009785
0.017613
0.068493
0.031311
0.023483
0.048924
0.037182
0.054795
0.021526
0.011742
0.031311
1
9,178
A
C
G
C
C
T
G
C
G
A
G
C
C
A
G
C
T
G
G
A
C
A
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C
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C
C
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G
C
C
C
C
A
C
T
T
C
C
T
G
C
T
C
A
A
G
T
G
0.019569
0.017613
0.031311
0.009785
0.033268
0.04501
0.015656
0.041096
0.031311
0.031311
0.048924
0.011742
0.021526
0.019569
0.019569
0.050881
0.076321
0.060665
0.060665
0.021526
0.005871
0.015656
0.013699
0.031311
0.023483
0.043053
0.033268
0.04501
0.041096
0.023483
0.017613
0.039139
1
9,179
C
T
G
G
G
C
T
G
C
C
C
C
A
T
G
C
T
G
T
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C
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A
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C
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C
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A
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A
T
G
C
T
G
G
C
A
C
C
T
G
G
A
G
C
A
C
C
T
0.02544
0.015656
0.037182
0.003914
0.043053
0.031311
0.005871
0.037182
0.039139
0.056751
0.050881
0.001957
0.017613
0.027397
0.027397
0.046967
0.074364
0.062622
0.058708
0.013699
0.003914
0
0.029354
0.041096
0.013699
0.033268
0.046967
0.056751
0.039139
0.019569
0.015656
0.023483
1
9,180
G
G
G
A
C
T
T
T
C
T
A
G
A
T
G
C
T
G
G
C
A
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C
C
T
G
G
G
G
A
A
C
T
C
C
G
A
G
C
A
C
T
C
0.023483
0.015656
0.041096
0.003914
0.041096
0.029354
0.003914
0.033268
0.037182
0.062622
0.050881
0.001957
0.017613
0.027397
0.029354
0.04501
0.078278
0.066536
0.058708
0.011742
0.003914
0
0.023483
0.043053
0.015656
0.029354
0.048924
0.056751
0.043053
0.017613
0.015656
0.023483
1
9,181
G
T
C
T
G
A
G
G
A
T
G
G
C
A
G
G
A
T
C
A
A
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A
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C
A
A
T
G
A
T
G
A
A
C
A
C
A
T
T
T
T
T
T
G
0.035225
0.02544
0.031311
0.029354
0.035225
0.033268
0.011742
0.023483
0.035225
0.033268
0.046967
0.003914
0.048924
0.046967
0.048924
0.035225
0.046967
0.058708
0.031311
0.013699
0.007828
0.009785
0.027397
0.033268
0.023483
0.027397
0.035225
0.043053
0.043053
0.015656
0.011742
0.046967
1
9,182
G
T
T
G
A
T
G
A
C
T
C
G
G
T
C
A
G
C
A
G
C
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T
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T
C
C
A
C
G
A
G
C
C
T
T
G
G
C
A
A
T
C
G
T
0.041096
0.023483
0.029354
0.027397
0.039139
0.027397
0.009785
0.021526
0.031311
0.033268
0.04501
0.007828
0.052838
0.048924
0.052838
0.037182
0.046967
0.062622
0.031311
0.013699
0.009785
0.009785
0.021526
0.033268
0.021526
0.023483
0.035225
0.050881
0.041096
0.013699
0.007828
0.048924
1
9,183
T
C
A
G
C
C
A
T
C
A
T
C
A
T
C
A
C
T
T
C
A
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C
C
A
G
C
T
T
C
A
T
G
T
T
C
T
T
G
G
T
A
C
0.039139
0.027397
0.033268
0.037182
0.039139
0.027397
0.005871
0.031311
0.056751
0.033268
0.048924
0.013699
0.039139
0.039139
0.029354
0.019569
0.066536
0.048924
0.021526
0
0.001957
0.007828
0.033268
0.035225
0.041096
0.035225
0.021526
0.023483
0.046967
0.021526
0.029354
0.04501
1
9,184
A
C
T
G
C
C
C
C
T
G
A
G
A
C
A
T
C
C
T
G
C
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A
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G
C
A
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A
G
G
T
G
A
G
C
A
T
C
C
T
G
G
G
C
T
C
T
G
A
0.04501
0.019569
0.041096
0.048924
0.037182
0.027397
0.007828
0.021526
0.046967
0.033268
0.048924
0.037182
0.033268
0.043053
0.035225
0.041096
0.035225
0.037182
0.019569
0.005871
0
0.005871
0.037182
0.037182
0.035225
0.019569
0.039139
0.027397
0.037182
0.015656
0.039139
0.041096
1
9,185
G
A
T
C
T
G
T
T
T
C
C
A
C
C
A
C
T
T
T
G
A
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G
G
A
C
A
A
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A
A
A
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G
T
C
T
C
C
T
T
0.037182
0.027397
0.033268
0.023483
0.043053
0.033268
0.005871
0.046967
0.04501
0.02544
0.039139
0.015656
0.037182
0.02544
0.039139
0.048924
0.054795
0.039139
0.037182
0.011742
0.009785
0.007828
0.017613
0.050881
0.021526
0.031311
0.037182
0.023483
0.035225
0.021526
0.023483
0.050881
1
9,186
C
A
G
G
A
G
A
C
A
T
T
T
T
T
C
T
T
G
T
C
C
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C
A
A
A
G
T
G
G
T
G
G
A
A
A
C
A
G
A
T
G
0.037182
0.027397
0.033268
0.023483
0.043053
0.033268
0.005871
0.046967
0.04501
0.02544
0.041096
0.015656
0.037182
0.02544
0.039139
0.048924
0.054795
0.039139
0.037182
0.011742
0.009785
0.007828
0.017613
0.050881
0.021526
0.031311
0.037182
0.023483
0.035225
0.021526
0.023483
0.048924
1
9,187
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0.037182
0.027397
0.033268
0.023483
0.043053
0.033268
0.005871
0.046967
0.04501
0.02544
0.041096
0.015656
0.037182
0.02544
0.039139
0.048924
0.054795
0.039139
0.037182
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0.009785
0.007828
0.017613
0.050881
0.021526
0.031311
0.037182
0.023483
0.035225
0.021526
0.023483
0.048924
1
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0.037182
0.027397
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0.039139
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0.050881
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0.037182
0.023483
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0.023483
0.050881
1
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0.039139
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0.037182
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0.056751
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0.037182
0.011742
0.009785
0.007828
0.017613
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0.021526
0.031311
0.037182
0.023483
0.035225
0.021526
0.023483
0.048924
1
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0.005871
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0.04501
0.02544
0.039139
0.015656
0.037182
0.029354
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0.048924
0.056751
0.039139
0.037182
0.011742
0.009785
0.007828
0.017613
0.048924
0.021526
0.031311
0.037182
0.023483
0.035225
0.021526
0.023483
0.048924
1