row_idx
int64
f_0_ref__32
string
f_1_ref__31
string
f_2_ref__30
string
f_3_ref__29
string
f_4_ref__28
string
f_5_ref__27
string
f_6_ref__26
string
f_7_ref__25
string
f_8_ref__24
string
f_9_ref__23
string
f_10_ref__22
string
f_11_ref__21
string
f_12_ref__20
string
f_13_ref__19
string
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string
f_15_ref__17
string
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string
f_17_ref__15
string
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string
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string
f_20_ref__12
string
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string
f_22_ref__10
string
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string
f_24_ref__8
string
f_25_ref__7
string
f_26_ref__6
string
f_27_ref__5
string
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string
f_29_ref__3
string
f_30_ref__2
string
f_31_ref__1
string
f_32_ref_0
string
f_33_ref__1
string
f_34_ref__2
string
f_35_ref__3
string
f_36_ref__4
string
f_37_ref__5
string
f_38_ref__6
string
f_39_ref__7
string
f_40_ref__8
string
f_41_ref__9
string
f_42_ref__10
string
f_43_ref__11
string
f_44_ref__12
string
f_45_ref__13
string
f_46_ref__14
string
f_47_ref__15
string
f_48_ref__16
string
f_49_ref__17
string
f_50_ref__18
string
f_51_ref__19
string
f_52_ref__20
string
f_53_ref__21
string
f_54_ref__22
string
f_55_ref__23
string
f_56_ref__24
string
f_57_ref__25
string
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string
f_59_ref__27
string
f_60_ref__28
string
f_61_ref__29
string
f_62_ref__30
string
f_63_ref__31
string
f_64_ref__32
string
f_65_alt
string
f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
int64
9,991
A
G
C
G
G
C
A
G
T
G
G
C
A
G
C
A
G
C
A
G
C
A
G
C
C
A
C
A
G
C
T
A
C
A
G
C
C
A
C
A
G
C
C
A
C
G
G
C
C
A
C
T
G
T
G
G
C
A
G
C
C
C
T
G
C
T
0.009785
0.021526
0.023483
0.007828
0.037182
0.029354
0.005871
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0.013699
0.039139
0.011742
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0.093933
0.064579
0.072407
0.021526
0
0.019569
0.017613
0.029354
0.023483
0.021526
0.064579
0.064579
0.043053
0.015656
0.017613
0.017613
1
9,992
A
G
C
A
G
C
A
G
C
A
G
C
C
A
C
A
G
C
T
A
C
A
G
C
C
A
C
A
G
C
C
A
C
G
G
C
C
A
C
T
G
T
G
G
C
A
G
C
C
C
T
G
C
A
G
G
A
G
A
C
A
C
A
G
A
T
0.009785
0.021526
0.021526
0.009785
0.037182
0.029354
0.007828
0.02544
0.029354
0.058708
0.048924
0.009785
0.013699
0.041096
0.009785
0.041096
0.093933
0.064579
0.07045
0.021526
0
0.021526
0.019569
0.027397
0.02544
0.021526
0.064579
0.062622
0.041096
0.015656
0.017613
0.017613
1
9,993
A
G
C
A
G
T
G
T
G
T
G
G
A
G
A
T
G
T
A
C
A
C
A
G
A
T
G
G
G
C
A
G
T
G
G
A
A
T
G
A
C
A
G
G
A
A
C
T
G
C
C
T
G
T
A
C
T
C
C
C
G
A
C
T
G
A
0.019569
0.015656
0.031311
0.023483
0.043053
0.019569
0.001957
0.039139
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0.04501
0.021526
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0.068493
0.052838
0.052838
0.011742
0.007828
0.005871
0.019569
0.043053
0.039139
0.029354
0.033268
0.050881
0.054795
0.023483
0.009785
0.041096
1
9,994
A
G
G
C
C
T
G
A
C
T
G
A
G
G
G
T
C
C
C
A
G
C
C
C
T
G
G
A
G
A
C
T
T
C
C
G
C
T
A
C
T
C
A
G
A
T
G
G
G
A
C
C
C
C
T
G
T
A
A
A
C
T
A
C
A
C
0.019569
0.015656
0.02544
0.017613
0.041096
0.019569
0.001957
0.041096
0.04501
0.02544
0.062622
0.007828
0.02544
0.046967
0.019569
0.027397
0.080235
0.052838
0.041096
0.011742
0.007828
0.005871
0.015656
0.052838
0.033268
0.037182
0.041096
0.048924
0.058708
0.02544
0.005871
0.039139
1
9,995
T
G
T
A
C
T
T
C
T
T
C
A
C
G
A
A
G
C
T
T
G
C
A
A
T
G
G
C
C
T
C
A
T
T
T
T
C
C
T
C
T
G
G
A
T
T
C
C
T
T
G
G
G
A
C
A
G
C
A
A
T
G
C
G
G
A
0.017613
0.009785
0.023483
0.019569
0.035225
0.027397
0.001957
0.039139
0.060665
0.027397
0.060665
0.007828
0.017613
0.04501
0.017613
0.029354
0.074364
0.052838
0.041096
0.011742
0.007828
0.005871
0.019569
0.068493
0.027397
0.039139
0.043053
0.048924
0.048924
0.027397
0.007828
0.035225
1
9,996
G
C
C
T
A
C
A
T
A
G
G
C
A
T
A
T
G
T
G
T
T
G
T
A
C
T
T
C
T
T
C
A
C
G
A
A
G
C
T
T
G
C
A
A
T
G
G
C
C
T
C
A
T
T
T
T
C
C
T
C
T
G
G
A
T
T
0.017613
0.009785
0.023483
0.019569
0.037182
0.027397
0.005871
0.039139
0.052838
0.029354
0.056751
0.007828
0.013699
0.041096
0.017613
0.029354
0.074364
0.050881
0.048924
0.019569
0.007828
0.009785
0.015656
0.062622
0.027397
0.043053
0.039139
0.050881
0.050881
0.027397
0.007828
0.035225
1
9,997
A
C
T
T
C
C
G
C
T
A
C
T
C
A
G
A
C
G
G
G
A
C
C
C
C
T
G
T
A
A
A
C
T
A
C
A
C
C
A
A
C
T
G
G
T
A
C
C
G
A
G
G
G
G
A
G
C
C
C
G
C
A
G
G
T
C
0.017613
0.013699
0.027397
0.023483
0.041096
0.017613
0.005871
0.039139
0.043053
0.029354
0.058708
0.009785
0.015656
0.04501
0.023483
0.029354
0.068493
0.050881
0.041096
0.017613
0.009785
0.009785
0.017613
0.058708
0.035225
0.035225
0.037182
0.054795
0.054795
0.02544
0.005871
0.037182
1
9,998
A
C
T
C
A
G
A
C
G
G
G
A
C
C
C
C
T
G
T
A
A
A
C
T
A
C
A
C
C
A
A
C
T
G
G
T
A
C
C
G
A
G
G
G
G
A
G
C
C
C
G
C
A
G
G
T
C
G
G
G
G
A
A
A
A
C
0.017613
0.013699
0.029354
0.023483
0.041096
0.019569
0.005871
0.039139
0.043053
0.029354
0.058708
0.009785
0.015656
0.04501
0.023483
0.031311
0.066536
0.050881
0.041096
0.017613
0.009785
0.009785
0.019569
0.054795
0.035225
0.035225
0.039139
0.052838
0.054795
0.02544
0.007828
0.033268
1
9,999
G
T
C
A
T
T
C
C
A
C
T
G
C
C
C
A
T
C
T
G
T
G
T
A
C
A
T
C
T
C
C
A
C
A
C
A
C
T
G
C
T
C
T
T
T
T
C
C
C
C
G
A
C
C
T
G
C
G
G
G
C
T
C
C
C
T
0.017613
0.013699
0.029354
0.02544
0.039139
0.017613
0.005871
0.039139
0.037182
0.027397
0.056751
0.009785
0.019569
0.046967
0.023483
0.033268
0.062622
0.054795
0.046967
0.017613
0.009785
0.009785
0.017613
0.052838
0.037182
0.031311
0.035225
0.056751
0.054795
0.023483
0.007828
0.039139
1
10,000
G
G
T
T
G
A
A
C
T
G
C
C
C
C
G
C
A
T
A
G
G
T
G
G
C
C
A
C
G
T
T
A
T
C
C
A
G
C
C
C
G
A
T
G
G
G
G
G
G
C
A
T
G
C
T
G
G
G
C
G
G
A
G
G
A
C
0.027397
0.019569
0.021526
0.003914
0.037182
0.041096
0.007828
0.019569
0.041096
0.046967
0.064579
0.009785
0.013699
0.021526
0.013699
0.056751
0.07045
0.066536
0.082192
0.011742
0.013699
0.005871
0.015656
0.064579
0.02544
0.019569
0.035225
0.056751
0.04501
0.009785
0.007828
0.023483
1
10,001
C
T
C
C
C
A
T
G
G
G
A
A
C
T
C
G
C
T
T
C
T
T
C
C
G
A
A
A
T
G
G
C
C
G
T
A
G
C
A
T
G
C
T
G
T
C
T
T
C
T
G
G
T
A
G
A
T
G
G
G
C
T
T
C
T
T
0.023483
0.023483
0.037182
0.011742
0.021526
0.035225
0.011742
0.009785
0.035225
0.046967
0.068493
0.009785
0.02544
0.04501
0.021526
0.023483
0.064579
0.07045
0.060665
0.007828
0.011742
0.019569
0.015656
0.043053
0.041096
0.019569
0.041096
0.048924
0.062622
0.011742
0.009785
0.021526
1
10,002
G
G
A
T
G
T
G
G
T
G
C
A
T
A
A
G
A
A
C
T
T
C
G
A
C
C
T
C
C
G
G
C
C
G
G
G
C
G
T
C
A
T
T
G
T
C
A
G
G
T
A
A
A
G
T
G
C
C
A
T
G
C
G
C
T
T
0.023483
0.017613
0.046967
0.013699
0.033268
0.037182
0.005871
0.015656
0.043053
0.046967
0.066536
0.005871
0.013699
0.033268
0.02544
0.041096
0.072407
0.048924
0.048924
0.015656
0.007828
0.013699
0.005871
0.046967
0.043053
0.023483
0.058708
0.048924
0.04501
0.009785
0.009785
0.031311
1
10,003
T
G
C
T
G
G
A
T
G
T
G
G
T
G
C
A
T
A
A
G
A
A
C
T
T
C
G
A
C
C
T
C
C
G
G
C
C
G
G
G
C
G
T
C
A
T
T
G
T
C
A
G
G
T
A
A
A
G
T
G
C
C
A
T
G
T
0.023483
0.017613
0.046967
0.013699
0.033268
0.037182
0.005871
0.015656
0.043053
0.046967
0.066536
0.007828
0.015656
0.033268
0.02544
0.041096
0.07045
0.048924
0.048924
0.015656
0.007828
0.013699
0.007828
0.04501
0.043053
0.023483
0.058708
0.048924
0.04501
0.009785
0.009785
0.029354
1
10,004
C
A
G
C
A
G
C
T
C
T
C
G
C
T
C
T
G
T
C
T
T
C
T
G
A
G
A
G
G
T
T
C
C
G
T
A
G
G
T
G
A
A
G
A
T
G
G
A
A
A
T
G
G
A
C
A
G
C
G
G
C
T
C
G
G
T
0.02544
0.015656
0.050881
0.015656
0.033268
0.037182
0.007828
0.011742
0.052838
0.043053
0.068493
0.007828
0.015656
0.031311
0.021526
0.041096
0.064579
0.037182
0.048924
0.017613
0.009785
0.015656
0.009785
0.048924
0.052838
0.021526
0.056751
0.041096
0.04501
0.011742
0.007828
0.031311
1
10,005
T
G
C
A
T
A
T
G
C
T
G
C
C
C
G
C
T
G
G
G
T
G
G
C
C
A
A
G
T
C
T
C
T
G
G
T
G
A
A
A
G
C
A
G
G
G
C
T
C
T
G
C
C
G
G
A
G
A
G
T
G
C
T
T
G
C
0.017613
0.019569
0.035225
0.011742
0.031311
0.037182
0.005871
0.02544
0.04501
0.043053
0.052838
0.009785
0.021526
0.023483
0.027397
0.046967
0.07045
0.058708
0.080235
0.021526
0.001957
0.009785
0.015656
0.04501
0.031311
0.017613
0.048924
0.054795
0.039139
0.013699
0.007828
0.029354
1
10,006
C
C
A
A
G
G
T
A
G
A
C
C
G
C
T
C
A
G
C
T
G
C
A
T
A
T
G
C
T
G
C
C
C
G
C
T
G
G
G
T
G
G
C
C
A
A
G
T
C
T
C
T
G
G
T
G
A
A
A
G
C
A
G
G
G
T
0.021526
0.017613
0.033268
0.013699
0.033268
0.035225
0.005871
0.023483
0.043053
0.04501
0.050881
0.009785
0.021526
0.02544
0.027397
0.048924
0.072407
0.060665
0.080235
0.019569
0
0.009785
0.013699
0.043053
0.029354
0.019569
0.048924
0.056751
0.041096
0.011742
0.007828
0.029354
1
10,007
C
C
C
A
G
C
C
G
C
C
A
T
A
G
G
T
G
T
C
C
A
C
A
A
T
A
A
T
C
T
T
A
C
G
G
C
C
A
G
T
G
A
C
A
C
C
C
G
C
A
T
C
C
C
C
C
T
G
C
A
G
A
G
G
G
T
0.015656
0.017613
0.039139
0.011742
0.027397
0.035225
0.003914
0.033268
0.041096
0.052838
0.046967
0.013699
0.015656
0.02544
0.023483
0.041096
0.078278
0.060665
0.076321
0.019569
0
0.007828
0.015656
0.041096
0.029354
0.027397
0.048924
0.048924
0.041096
0.013699
0.015656
0.031311
1
10,008
T
C
C
C
T
C
T
G
C
A
G
G
G
G
G
A
T
G
C
G
G
G
T
G
T
C
A
C
T
G
G
C
C
G
T
A
A
G
A
T
T
A
T
T
G
T
G
G
A
C
A
C
C
T
A
T
G
G
C
G
G
C
T
G
G
T
0.015656
0.017613
0.039139
0.011742
0.027397
0.037182
0.003914
0.033268
0.041096
0.052838
0.046967
0.013699
0.015656
0.02544
0.023483
0.041096
0.078278
0.060665
0.076321
0.019569
0
0.007828
0.015656
0.041096
0.029354
0.027397
0.046967
0.048924
0.041096
0.013699
0.015656
0.031311
1
10,009
T
A
T
C
T
T
G
A
T
T
T
C
T
C
T
C
C
C
T
C
T
G
C
A
G
G
G
G
G
A
T
G
C
G
G
G
T
G
T
C
A
C
T
G
G
C
C
G
T
A
A
G
A
T
T
A
T
T
G
T
G
G
A
C
A
T
0.013699
0.019569
0.037182
0.011742
0.027397
0.037182
0.003914
0.033268
0.043053
0.048924
0.048924
0.013699
0.015656
0.02544
0.023483
0.041096
0.078278
0.062622
0.078278
0.015656
0
0.007828
0.015656
0.041096
0.029354
0.027397
0.046967
0.052838
0.039139
0.013699
0.015656
0.031311
1
10,010
C
C
A
C
A
A
T
A
A
T
C
T
T
A
C
G
G
C
C
A
G
T
G
A
C
A
C
C
C
G
C
A
T
C
C
C
C
C
T
G
C
A
G
A
G
G
G
A
G
A
G
A
A
A
T
C
A
A
G
A
T
A
A
G
A
A
0.013699
0.019569
0.037182
0.011742
0.027397
0.037182
0.003914
0.033268
0.04501
0.048924
0.048924
0.013699
0.015656
0.02544
0.023483
0.041096
0.080235
0.060665
0.078278
0.015656
0
0.007828
0.015656
0.043053
0.029354
0.027397
0.046967
0.048924
0.039139
0.013699
0.015656
0.031311
1
10,011
C
A
G
G
G
C
C
A
G
G
G
C
G
G
C
C
C
A
C
C
G
G
C
A
G
C
G
C
C
T
C
A
T
G
T
C
T
C
C
G
C
C
G
G
C
G
C
G
G
A
G
T
G
T
C
G
C
C
T
G
C
C
G
C
C
A
0
0
0.011742
0.007828
0.011742
0.027397
0.015656
0.021526
0.027397
0.046967
0.039139
0
0.011742
0.023483
0.005871
0.037182
0.052838
0.064579
0.086106
0.080235
0.017613
0.09002
0.011742
0.058708
0.009785
0.031311
0.031311
0.099804
0.054795
0.007828
0.003914
0.011742
1
10,012
T
T
A
T
C
A
C
A
C
T
G
C
T
G
G
A
T
G
T
C
A
A
T
G
A
C
C
A
C
C
C
C
C
C
T
C
A
G
T
T
T
G
G
A
A
A
G
A
G
C
G
T
T
C
A
G
A
A
G
A
A
G
A
C
G
G
0.043053
0.013699
0.039139
0.029354
0.039139
0.02544
0.009785
0.021526
0.037182
0.050881
0.04501
0.041096
0.023483
0.046967
0.027397
0.039139
0.058708
0.052838
0.041096
0
0.001957
0.007828
0.019569
0.037182
0.031311
0.019569
0.043053
0.035225
0.037182
0.023483
0.021526
0.037182
1
10,013
C
C
T
G
G
A
C
A
C
T
G
T
G
A
G
G
A
A
G
G
C
A
G
C
A
A
G
G
T
T
G
G
C
T
G
T
G
T
A
G
G
A
G
G
A
G
C
A
C
A
C
A
A
T
G
A
G
C
G
T
G
A
A
G
A
T
0.023483
0.015656
0.029354
0.029354
0.039139
0.023483
0.007828
0.019569
0.041096
0.043053
0.056751
0.019569
0.037182
0.041096
0.021526
0.046967
0.07045
0.064579
0.031311
0.003914
0.005871
0.009785
0.007828
0.052838
0.029354
0.013699
0.043053
0.048924
0.052838
0.013699
0.023483
0.033268
1
10,014
C
C
C
C
T
G
G
C
C
A
C
A
G
C
T
G
C
T
G
C
C
C
A
C
A
C
T
G
C
C
A
T
C
G
C
C
T
C
C
G
C
C
T
C
C
A
C
C
A
C
A
G
C
C
C
C
T
G
C
T
T
C
A
A
G
G
0.011742
0.009785
0.027397
0.005871
0.033268
0.04501
0.001957
0.019569
0.023483
0.056751
0.072407
0.001957
0.003914
0.011742
0.017613
0.060665
0.09589
0.066536
0.078278
0.019569
0.005871
0.027397
0.015656
0.033268
0.019569
0.021526
0.066536
0.086106
0.027397
0.007828
0.005871
0.019569
1
10,015
T
A
G
C
C
A
T
G
G
G
C
C
G
T
T
C
T
T
G
G
C
A
C
C
C
T
G
A
A
G
A
G
T
T
C
A
C
C
T
G
T
G
C
C
T
A
C
T
G
C
A
A
G
A
C
T
T
C
C
C
T
G
G
C
A
A
0.04501
0.037182
0.054795
0.037182
0.041096
0.021526
0.007828
0.035225
0.048924
0.031311
0.02544
0.017613
0.019569
0.037182
0.043053
0.039139
0.048924
0.054795
0.052838
0.003914
0.003914
0.003914
0.007828
0.029354
0.056751
0.009785
0.043053
0.031311
0.031311
0.019569
0.029354
0.031311
1
10,016
G
T
T
T
A
C
T
G
T
G
A
G
C
G
A
T
G
T
T
A
T
G
A
G
C
A
A
T
T
C
T
T
T
G
C
C
C
C
G
C
T
G
T
G
T
G
C
C
A
A
G
T
G
C
A
A
C
A
C
C
A
A
A
A
T
A
0.043053
0.037182
0.054795
0.035225
0.041096
0.023483
0.007828
0.035225
0.043053
0.029354
0.027397
0.019569
0.023483
0.031311
0.050881
0.04501
0.04501
0.064579
0.058708
0.003914
0.003914
0.003914
0.009785
0.02544
0.046967
0.009785
0.041096
0.035225
0.035225
0.015656
0.029354
0.023483
1
10,017
A
G
G
G
G
C
A
G
C
C
G
T
T
C
T
A
C
T
C
C
A
A
G
A
A
G
G
A
C
A
G
A
C
C
C
C
T
G
T
G
C
A
A
G
A
A
G
C
A
C
G
C
A
C
A
C
A
C
C
A
T
C
A
A
C
T
0.043053
0.023483
0.041096
0.019569
0.031311
0.019569
0.017613
0.029354
0.050881
0.037182
0.052838
0.005871
0.023483
0.02544
0.035225
0.035225
0.064579
0.050881
0.029354
0.011742
0.009785
0.015656
0.019569
0.04501
0.037182
0.02544
0.04501
0.058708
0.037182
0.013699
0.011742
0.033268
1
10,018
C
C
C
A
A
T
A
A
T
C
T
G
A
T
G
T
A
A
A
T
G
T
A
T
A
G
C
T
G
A
G
G
C
A
T
T
G
T
T
C
A
A
T
T
G
T
A
A
T
G
T
T
T
C
C
T
G
T
G
T
A
C
T
G
T
T
0.111546
0.035225
0.050881
0.07045
0.054795
0.011742
0.007828
0.037182
0.02544
0.02544
0.029354
0.035225
0.021526
0.033268
0.054795
0.031311
0.027397
0.019569
0.013699
0
0.005871
0.001957
0.02544
0.013699
0.052838
0.013699
0.021526
0.017613
0.019569
0.031311
0.048924
0.050881
1
10,019
C
C
C
A
A
T
A
A
T
C
T
G
A
T
G
T
A
A
A
T
G
T
A
T
A
G
C
T
G
A
G
G
C
A
T
T
G
T
T
C
A
A
T
T
G
T
A
A
T
G
T
T
T
C
C
T
G
T
G
T
A
C
T
G
T
G
0.111546
0.035225
0.050881
0.07045
0.054795
0.011742
0.007828
0.037182
0.02544
0.02544
0.029354
0.035225
0.021526
0.033268
0.054795
0.031311
0.027397
0.019569
0.013699
0
0.005871
0.001957
0.02544
0.013699
0.052838
0.013699
0.021526
0.017613
0.019569
0.031311
0.048924
0.050881
1
10,020
C
A
A
A
A
G
C
C
C
A
G
C
T
A
C
G
C
C
G
G
A
C
A
A
T
A
G
A
A
T
G
T
T
G
T
C
G
G
A
C
C
A
A
T
T
T
A
T
G
T
A
A
C
C
A
G
T
A
T
T
T
G
C
A
A
G
0.111546
0.033268
0.027397
0.072407
0.04501
0.02544
0.007828
0.023483
0.043053
0.02544
0.017613
0.050881
0.021526
0.043053
0.041096
0.019569
0.037182
0.031311
0.013699
0.011742
0.009785
0.001957
0.029354
0.015656
0.043053
0.021526
0.029354
0.021526
0.013699
0.027397
0.048924
0.035225
1
10,021
G
C
C
G
G
A
C
A
A
T
A
G
A
A
T
G
T
T
G
T
C
G
G
A
C
C
A
A
T
T
T
A
T
G
T
A
A
C
C
A
G
T
A
T
T
T
G
C
A
A
C
C
C
A
C
A
C
T
G
C
C
C
C
C
T
C
0.111546
0.031311
0.027397
0.076321
0.039139
0.023483
0.007828
0.023483
0.04501
0.027397
0.017613
0.050881
0.02544
0.043053
0.043053
0.013699
0.037182
0.027397
0.013699
0.011742
0.009785
0.001957
0.031311
0.015656
0.043053
0.021526
0.031311
0.021526
0.011742
0.027397
0.048924
0.039139
1
10,022
A
T
T
T
A
A
C
A
G
C
A
A
G
G
C
C
C
A
G
G
T
C
A
G
C
A
A
T
G
C
A
G
C
A
A
C
T
C
C
C
A
T
T
T
T
T
C
T
T
G
A
T
G
A
G
G
A
T
G
T
T
T
T
T
G
T
0.099804
0.023483
0.031311
0.07045
0.046967
0.023483
0
0.019569
0.035225
0.031311
0.031311
0.056751
0.021526
0.039139
0.04501
0.029354
0.041096
0.035225
0.02544
0.003914
0.003914
0.003914
0.021526
0.023483
0.039139
0.015656
0.039139
0.019569
0.027397
0.021526
0.041096
0.033268
1
10,023
C
C
T
A
A
T
A
G
G
G
T
G
C
A
T
C
T
G
A
G
A
A
A
G
A
C
A
T
C
G
T
G
C
A
C
T
C
T
G
G
C
T
T
G
G
C
A
T
A
C
A
C
A
A
T
G
G
A
G
C
G
T
T
C
T
T
0.088063
0.033268
0.043053
0.041096
0.07045
0.013699
0.003914
0.029354
0.050881
0.033268
0.017613
0.054795
0.035225
0.041096
0.060665
0.033268
0.046967
0.021526
0.007828
0.001957
0.001957
0.003914
0.019569
0.019569
0.031311
0.027397
0.043053
0.013699
0.013699
0.023483
0.027397
0.046967
1
10,024
T
G
T
G
T
A
T
G
C
C
A
A
G
C
C
A
G
A
G
T
G
C
A
C
G
A
T
G
T
C
T
T
T
C
T
C
A
G
A
T
G
C
A
C
C
C
T
A
T
T
A
G
G
G
A
A
A
A
G
A
A
C
A
C
A
C
0.086106
0.033268
0.043053
0.039139
0.07045
0.013699
0.003914
0.029354
0.050881
0.033268
0.017613
0.052838
0.035225
0.04501
0.060665
0.033268
0.046967
0.021526
0.007828
0.001957
0.001957
0.003914
0.019569
0.021526
0.029354
0.027397
0.043053
0.013699
0.013699
0.023483
0.02544
0.050881
1
10,025
T
A
A
A
C
T
T
G
T
G
T
T
C
T
T
T
T
C
C
C
T
A
A
T
A
G
G
G
T
G
C
A
T
C
T
G
A
G
A
A
A
G
A
C
A
T
C
G
T
G
C
A
C
T
C
T
G
G
C
T
T
G
G
C
A
C
0.084149
0.033268
0.041096
0.041096
0.07045
0.013699
0.003914
0.029354
0.050881
0.031311
0.017613
0.056751
0.037182
0.04501
0.058708
0.033268
0.046967
0.019569
0.007828
0.001957
0.001957
0.003914
0.021526
0.021526
0.029354
0.027397
0.043053
0.013699
0.011742
0.023483
0.027397
0.050881
1
10,026
A
G
C
C
A
G
A
G
T
G
C
A
C
G
A
T
G
T
C
T
T
T
C
T
C
A
G
A
T
G
C
A
C
C
C
T
A
T
T
A
G
G
G
A
A
A
A
G
A
A
C
A
C
A
A
G
T
T
T
A
A
C
A
A
A
A
0.084149
0.033268
0.041096
0.041096
0.072407
0.013699
0.003914
0.031311
0.050881
0.031311
0.015656
0.056751
0.037182
0.04501
0.058708
0.033268
0.046967
0.019569
0.007828
0.001957
0.001957
0.003914
0.021526
0.019569
0.029354
0.027397
0.043053
0.011742
0.011742
0.027397
0.027397
0.048924
1
10,027
A
G
C
C
A
G
A
G
T
G
C
A
C
G
A
T
G
T
C
T
T
T
C
T
C
A
G
A
T
G
C
A
C
C
C
T
A
T
T
A
G
G
G
A
A
A
A
G
A
A
C
A
C
A
A
G
T
T
T
A
A
C
A
A
A
T
0.084149
0.033268
0.041096
0.041096
0.072407
0.013699
0.003914
0.031311
0.050881
0.031311
0.015656
0.056751
0.037182
0.04501
0.058708
0.033268
0.046967
0.019569
0.007828
0.001957
0.001957
0.003914
0.021526
0.019569
0.029354
0.027397
0.043053
0.011742
0.011742
0.027397
0.027397
0.048924
1
10,028
T
G
T
A
C
C
C
A
C
G
G
C
A
G
A
G
T
T
C
C
A
A
G
A
C
A
G
G
A
T
A
T
C
G
G
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G
A
G
T
G
T
G
G
T
G
A
C
C
C
C
A
C
A
G
T
T
G
T
A
C
T
T
C
A
T
0.101761
0.033268
0.037182
0.039139
0.056751
0.021526
0.013699
0.048924
0.048924
0.021526
0.017613
0.035225
0.02544
0.023483
0.033268
0.04501
0.043053
0.033268
0.015656
0.005871
0.003914
0.007828
0.029354
0.027397
0.037182
0.02544
0.021526
0.007828
0.027397
0.037182
0.039139
0.035225
1
10,029
T
A
T
A
A
A
A
A
T
G
T
A
T
T
A
A
T
A
C
C
A
A
T
T
T
G
A
A
G
T
C
T
T
C
C
A
G
T
T
C
C
T
T
T
G
G
G
T
C
A
A
T
A
C
C
A
T
C
T
G
G
A
T
T
C
G
0.07045
0.021526
0.035225
0.07045
0.039139
0.027397
0.003914
0.029354
0.039139
0.029354
0.017613
0.058708
0.02544
0.041096
0.058708
0.02544
0.037182
0.056751
0.023483
0.001957
0.003914
0.001957
0.021526
0.021526
0.031311
0.027397
0.029354
0.021526
0.027397
0.02544
0.039139
0.037182
1
10,030
C
A
G
C
A
A
T
A
C
A
T
T
T
A
G
C
A
C
C
A
A
A
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T
A
A
A
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T
C
A
T
A
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A
G
T
G
T
A
G
G
C
C
C
A
C
A
T
T
A
C
C
A
A
A
T
C
0.074364
0.02544
0.035225
0.080235
0.043053
0.02544
0.003914
0.023483
0.043053
0.029354
0.015656
0.054795
0.021526
0.046967
0.054795
0.023483
0.029354
0.052838
0.021526
0.003914
0.001957
0.003914
0.021526
0.02544
0.039139
0.017613
0.02544
0.021526
0.02544
0.029354
0.046967
0.033268
1
10,031
G
G
G
G
A
A
T
C
C
A
T
G
G
A
C
G
C
A
T
C
T
C
T
G
C
T
A
C
T
G
G
C
C
G
T
G
G
T
G
T
C
T
T
C
C
A
T
G
G
G
A
T
T
G
A
A
A
A
T
T
T
C
A
T
C
T
0.11546
0.033268
0.041096
0.082192
0.048924
0.021526
0.005871
0.029354
0.041096
0.013699
0.021526
0.033268
0.023483
0.048924
0.041096
0.02544
0.023483
0.029354
0.017613
0.001957
0
0.003914
0.017613
0.02544
0.043053
0.017613
0.013699
0.007828
0.023483
0.029354
0.072407
0.046967
1
10,032
C
T
C
T
C
T
T
C
T
A
G
A
G
C
C
G
A
G
G
G
A
C
C
C
G
G
T
G
G
C
C
T
C
G
T
C
G
C
T
C
A
G
C
C
C
C
T
A
T
T
T
C
G
G
C
A
C
C
A
A
G
A
C
T
C
T
0.003914
0.007828
0.013699
0.005871
0.007828
0.037182
0.023483
0.009785
0.021526
0.072407
0.04501
0.003914
0.013699
0.011742
0.013699
0.023483
0.056751
0.027397
0.072407
0.086106
0.035225
0.074364
0.02544
0.052838
0.013699
0.033268
0.056751
0.078278
0.043053
0.015656
0
0.013699
1
10,033
T
A
T
T
A
C
C
T
G
C
A
T
T
T
A
A
A
T
C
A
T
T
T
A
C
T
G
G
C
A
C
T
T
G
C
A
A
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T
A
G
C
T
G
C
A
A
C
T
T
T
T
T
T
T
A
A
A
A
T
G
T
T
C
C
0.148728
0.041096
0.041096
0.076321
0.046967
0.013699
0.003914
0.04501
0.041096
0.013699
0.009785
0.050881
0.023483
0.039139
0.037182
0.021526
0.037182
0.019569
0.003914
0
0
0
0.017613
0.013699
0.04501
0.017613
0.021526
0.003914
0.011742
0.029354
0.078278
0.046967
1
10,034
G
G
G
T
G
G
G
T
T
C
C
G
A
G
G
A
T
G
T
A
C
C
G
T
G
T
G
G
C
T
A
A
C
A
G
G
T
A
T
G
T
C
A
T
G
T
T
C
A
T
A
T
A
T
A
T
A
T
A
T
A
T
A
T
A
G
0.064579
0.039139
0.037182
0.048924
0.054795
0.02544
0.005871
0.039139
0.043053
0.015656
0.027397
0.082192
0.021526
0.039139
0.041096
0.033268
0.029354
0.035225
0.015656
0.003914
0.003914
0.001957
0.029354
0.029354
0.033268
0.023483
0.017613
0.015656
0.02544
0.029354
0.050881
0.037182
1
10,035
C
T
G
C
T
G
A
T
T
C
A
T
G
T
A
T
T
T
T
G
C
G
G
G
C
A
T
T
C
T
C
A
C
G
A
T
C
C
T
G
A
A
A
A
G
C
A
A
T
A
T
G
A
T
T
A
A
G
A
A
T
G
T
A
A
T
0.093933
0.021526
0.043053
0.054795
0.035225
0.015656
0.009785
0.027397
0.054795
0.033268
0.035225
0.037182
0.019569
0.033268
0.037182
0.029354
0.04501
0.027397
0.017613
0.003914
0.001957
0.003914
0.023483
0.041096
0.048924
0.015656
0.037182
0.027397
0.023483
0.023483
0.033268
0.04501
1
10,036
G
C
T
G
A
T
G
C
C
C
C
T
C
G
C
T
C
T
G
C
C
G
C
C
G
C
T
T
G
G
C
T
C
T
G
G
A
C
C
G
C
A
G
C
C
G
G
G
T
A
A
T
G
G
C
T
G
C
T
G
C
G
G
C
G
G
0.027397
0.013699
0.031311
0.013699
0.015656
0.021526
0.011742
0.009785
0.046967
0.058708
0.039139
0.007828
0.029354
0.027397
0.015656
0.015656
0.068493
0.048924
0.037182
0.072407
0.013699
0.046967
0.005871
0.046967
0.029354
0.021526
0.04501
0.09002
0.048924
0.007828
0.013699
0.017613
1
10,037
T
C
T
G
C
T
A
A
C
G
A
T
C
T
C
T
T
T
G
A
T
G
A
T
G
G
C
T
G
T
C
A
T
G
T
C
T
G
G
G
A
G
C
C
T
G
T
G
G
C
T
G
A
A
G
A
A
A
A
A
G
G
A
G
G
C
0.039139
0.021526
0.035225
0.017613
0.027397
0.027397
0.011742
0.015656
0.056751
0.056751
0.039139
0.019569
0.027397
0.033268
0.023483
0.017613
0.068493
0.048924
0.02544
0.029354
0.013699
0.027397
0.023483
0.041096
0.037182
0.029354
0.041096
0.050881
0.039139
0.013699
0.015656
0.02544
1
10,038
C
T
C
C
T
T
T
T
T
C
T
T
C
A
G
C
C
A
C
A
G
G
C
T
C
C
C
A
G
A
C
A
T
G
A
C
A
G
C
C
A
T
C
A
T
C
A
A
A
G
A
G
A
T
C
G
T
T
A
G
C
A
G
A
A
C
0.039139
0.021526
0.035225
0.017613
0.027397
0.027397
0.011742
0.015656
0.056751
0.056751
0.039139
0.019569
0.027397
0.033268
0.023483
0.017613
0.068493
0.048924
0.02544
0.029354
0.013699
0.027397
0.02544
0.041096
0.035225
0.029354
0.041096
0.050881
0.039139
0.013699
0.015656
0.02544
1
10,039
T
T
T
C
T
G
C
T
A
A
C
G
A
T
C
T
C
T
T
T
G
A
T
G
A
T
G
G
C
T
G
T
C
A
T
G
T
C
T
G
G
G
A
G
C
C
T
G
T
G
G
C
T
G
A
A
G
A
A
A
A
A
G
G
A
T
0.039139
0.021526
0.035225
0.017613
0.027397
0.027397
0.011742
0.015656
0.058708
0.056751
0.039139
0.019569
0.027397
0.033268
0.023483
0.017613
0.068493
0.048924
0.02544
0.029354
0.011742
0.027397
0.02544
0.041096
0.035225
0.029354
0.041096
0.050881
0.039139
0.013699
0.015656
0.02544
1
10,040
A
T
A
T
C
T
C
C
T
T
T
T
G
T
T
T
C
T
G
C
T
A
A
C
G
A
T
C
T
C
T
T
T
G
A
T
G
A
T
G
G
C
T
G
T
C
A
T
G
T
C
T
G
G
G
A
G
C
C
T
G
T
G
G
C
C
0.039139
0.023483
0.035225
0.015656
0.027397
0.027397
0.011742
0.017613
0.056751
0.056751
0.039139
0.019569
0.027397
0.031311
0.02544
0.017613
0.068493
0.046967
0.021526
0.031311
0.011742
0.027397
0.02544
0.041096
0.035225
0.029354
0.043053
0.052838
0.039139
0.013699
0.015656
0.02544
1
10,041
A
G
T
C
G
A
A
T
C
C
A
T
C
C
T
C
T
T
G
A
T
A
T
C
T
C
C
T
T
T
T
G
T
T
T
C
T
G
C
T
A
A
C
G
A
T
C
T
C
T
T
T
G
A
T
G
A
T
G
G
C
T
G
T
C
G
0.039139
0.02544
0.039139
0.015656
0.029354
0.029354
0.011742
0.019569
0.056751
0.054795
0.041096
0.019569
0.027397
0.031311
0.031311
0.019569
0.064579
0.046967
0.021526
0.02544
0.011742
0.021526
0.02544
0.041096
0.033268
0.031311
0.043053
0.048924
0.037182
0.013699
0.015656
0.027397
1
10,042
A
A
T
G
G
A
T
A
C
A
G
G
T
C
A
A
G
T
C
T
A
A
G
T
C
G
A
A
T
C
C
A
T
C
C
T
C
T
T
G
A
T
A
T
C
T
C
C
T
T
T
T
G
T
T
T
C
T
G
C
T
A
A
C
G
A
0.041096
0.02544
0.043053
0.017613
0.029354
0.031311
0.011742
0.019569
0.054795
0.054795
0.037182
0.019569
0.029354
0.031311
0.033268
0.021526
0.058708
0.046967
0.021526
0.027397
0.013699
0.021526
0.029354
0.035225
0.033268
0.031311
0.043053
0.04501
0.035225
0.013699
0.017613
0.02544
1
10,043
G
G
A
G
C
A
G
C
C
G
C
A
G
A
A
A
T
G
G
A
T
A
C
A
G
G
T
C
A
A
G
T
C
T
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A
G
T
C
G
A
A
T
C
C
A
T
C
C
T
C
T
T
G
A
T
A
T
C
T
C
C
T
T
T
A
0.041096
0.02544
0.041096
0.017613
0.029354
0.033268
0.011742
0.017613
0.060665
0.052838
0.035225
0.027397
0.031311
0.033268
0.033268
0.021526
0.054795
0.046967
0.019569
0.027397
0.011742
0.019569
0.031311
0.037182
0.033268
0.031311
0.041096
0.041096
0.035225
0.013699
0.017613
0.02544
1
10,044
A
A
A
G
A
G
G
A
G
C
A
G
C
C
G
C
A
G
A
A
A
T
G
G
A
T
A
C
A
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G
T
C
A
A
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T
C
T
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A
G
T
C
G
A
A
T
C
C
A
T
C
C
T
C
T
T
G
A
T
A
T
C
T
G
0.041096
0.02544
0.043053
0.017613
0.029354
0.033268
0.011742
0.017613
0.060665
0.050881
0.037182
0.027397
0.031311
0.033268
0.031311
0.021526
0.054795
0.046967
0.019569
0.027397
0.011742
0.019569
0.031311
0.037182
0.035225
0.031311
0.037182
0.041096
0.037182
0.013699
0.017613
0.02544
1
10,045
T
A
A
A
G
A
G
G
A
G
C
A
G
C
C
G
C
A
G
A
A
A
T
G
G
A
T
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C
A
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G
T
C
A
A
G
T
C
T
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A
G
T
C
G
A
A
T
C
C
A
T
C
C
T
C
T
T
G
A
T
A
T
C
G
0.041096
0.023483
0.043053
0.017613
0.029354
0.033268
0.011742
0.017613
0.060665
0.050881
0.037182
0.027397
0.031311
0.033268
0.031311
0.021526
0.054795
0.046967
0.019569
0.027397
0.011742
0.019569
0.031311
0.037182
0.035225
0.031311
0.037182
0.041096
0.037182
0.013699
0.017613
0.027397
1
10,046
G
T
A
C
T
C
A
G
A
T
A
T
T
T
A
T
C
C
A
A
A
C
A
T
T
A
T
T
G
C
T
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T
G
G
G
A
T
T
T
C
C
T
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C
A
G
A
A
A
G
A
C
T
T
G
A
A
G
G
C
G
T
A
T
G
0.105675
0.035225
0.046967
0.060665
0.041096
0.019569
0.003914
0.041096
0.037182
0.019569
0.019569
0.082192
0.031311
0.04501
0.031311
0.017613
0.029354
0.023483
0.011742
0.001957
0
0.001957
0.031311
0.009785
0.050881
0.009785
0.015656
0.005871
0.021526
0.04501
0.060665
0.043053
1
10,047
T
A
T
T
T
A
T
C
C
A
A
A
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A
T
T
A
T
T
G
C
T
A
T
G
G
G
A
T
T
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C
C
T
G
C
A
G
A
A
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A
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T
T
G
A
A
G
G
C
G
T
A
T
A
C
A
G
G
A
A
C
A
G
0.103718
0.033268
0.048924
0.062622
0.043053
0.019569
0.003914
0.039139
0.035225
0.019569
0.021526
0.086106
0.031311
0.046967
0.031311
0.015656
0.027397
0.023483
0.011742
0.001957
0
0.001957
0.031311
0.007828
0.048924
0.009785
0.015656
0.005871
0.021526
0.046967
0.062622
0.041096
1
10,048
T
T
A
C
T
A
C
A
T
C
A
T
C
A
A
T
A
T
T
G
T
T
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C
T
G
C
A
G
G
A
A
A
T
C
C
C
A
T
A
G
C
A
T
0.097847
0.031311
0.050881
0.064579
0.043053
0.019569
0.003914
0.041096
0.033268
0.019569
0.021526
0.084149
0.033268
0.046967
0.031311
0.015656
0.027397
0.023483
0.011742
0.001957
0
0.001957
0.031311
0.005871
0.046967
0.009785
0.015656
0.005871
0.021526
0.050881
0.068493
0.039139
1
10,049
T
T
C
T
T
A
C
C
T
T
A
C
T
A
C
A
T
C
A
T
C
A
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G
T
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C
C
T
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T
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T
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C
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A
A
G
T
C
T
T
T
C
T
G
C
A
G
G
A
A
A
T
C
C
0.097847
0.031311
0.050881
0.062622
0.043053
0.019569
0.003914
0.039139
0.033268
0.019569
0.021526
0.086106
0.037182
0.048924
0.031311
0.017613
0.02544
0.023483
0.011742
0.001957
0
0.001957
0.031311
0.005871
0.04501
0.007828
0.015656
0.005871
0.021526
0.048924
0.068493
0.041096
1
10,050
C
C
T
G
C
A
G
A
A
A
G
A
C
T
T
G
A
A
G
G
C
G
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A
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A
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A
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A
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G
T
A
G
T
A
A
G
G
T
A
A
G
A
A
T
G
C
T
T
A
0.099804
0.031311
0.050881
0.064579
0.041096
0.019569
0.003914
0.039139
0.033268
0.019569
0.021526
0.086106
0.037182
0.046967
0.031311
0.017613
0.02544
0.021526
0.011742
0.001957
0
0.001957
0.031311
0.005871
0.046967
0.007828
0.015656
0.005871
0.019569
0.048924
0.068493
0.043053
1
10,051
C
C
T
G
C
A
G
A
A
A
G
A
C
T
T
G
A
A
G
G
C
G
T
A
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A
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A
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A
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G
T
A
G
T
A
A
G
G
T
A
A
G
A
A
T
G
C
T
T
G
0.099804
0.031311
0.050881
0.064579
0.041096
0.019569
0.003914
0.039139
0.033268
0.019569
0.021526
0.086106
0.037182
0.046967
0.031311
0.017613
0.02544
0.021526
0.011742
0.001957
0
0.001957
0.031311
0.005871
0.046967
0.007828
0.015656
0.005871
0.019569
0.048924
0.068493
0.043053
1
10,052
G
C
A
T
A
C
A
A
A
T
A
A
G
A
A
A
A
C
A
T
A
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T
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A
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T
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G
G
T
T
T
T
T
A
T
G
C
T
T
T
G
A
A
T
C
C
C
0.111546
0.04501
0.050881
0.076321
0.056751
0.019569
0
0.031311
0.050881
0.017613
0.011742
0.04501
0.039139
0.046967
0.054795
0.015656
0.013699
0.023483
0.007828
0.001957
0.001957
0
0.031311
0.015656
0.031311
0.009785
0.017613
0.007828
0.009785
0.037182
0.084149
0.033268
1
10,053
T
G
T
G
C
T
G
A
A
A
G
A
C
A
T
T
A
T
G
A
C
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C
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A
G
G
T
A
T
G
A
A
T
G
T
A
C
T
G
T
A
C
T
G
0.101761
0.031311
0.048924
0.084149
0.052838
0.011742
0
0.046967
0.039139
0.013699
0.015656
0.082192
0.02544
0.039139
0.027397
0.023483
0.023483
0.007828
0.007828
0.003914
0.005871
0.001957
0.035225
0.007828
0.031311
0.019569
0.023483
0.003914
0.011742
0.037182
0.107632
0.027397
1
10,054
A
G
G
G
T
T
T
G
A
T
A
A
G
T
T
C
T
A
G
C
T
G
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G
T
G
G
G
T
T
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T
G
G
T
C
T
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C
A
A
A
A
G
G
A
T
A
T
T
G
T
G
C
A
A
C
T
G
T
G
G
T
A
C
0.109589
0.035225
0.062622
0.064579
0.039139
0.02544
0.001957
0.029354
0.046967
0.015656
0.031311
0.048924
0.031311
0.031311
0.041096
0.021526
0.02544
0.029354
0.021526
0.001957
0.003914
0
0.021526
0.013699
0.04501
0.015656
0.023483
0.011742
0.02544
0.023483
0.074364
0.027397
1
10,055
A
G
T
T
G
C
A
C
A
A
T
A
T
C
C
T
T
T
T
G
A
A
G
A
C
C
A
T
A
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C
C
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C
A
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A
G
C
T
A
G
A
A
C
T
T
A
T
C
A
A
A
C
C
C
T
T
T
T
G
T
G
T
0.107632
0.035225
0.062622
0.062622
0.039139
0.02544
0.001957
0.029354
0.050881
0.015656
0.031311
0.048924
0.031311
0.029354
0.041096
0.021526
0.027397
0.027397
0.017613
0.001957
0.003914
0
0.021526
0.015656
0.046967
0.015656
0.023483
0.011742
0.02544
0.023483
0.074364
0.029354
1
10,056
T
T
G
C
A
C
A
A
T
A
T
C
C
T
T
T
T
G
A
A
G
A
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C
A
T
A
A
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C
C
A
C
C
A
C
A
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C
T
A
G
A
A
C
T
T
A
T
C
A
A
A
C
C
C
T
T
T
T
G
T
G
A
A
G
0.107632
0.035225
0.062622
0.066536
0.039139
0.02544
0.001957
0.029354
0.050881
0.015656
0.031311
0.048924
0.031311
0.029354
0.041096
0.021526
0.027397
0.027397
0.015656
0.001957
0.003914
0
0.021526
0.015656
0.046967
0.015656
0.023483
0.011742
0.023483
0.023483
0.074364
0.029354
1
10,057
T
T
G
C
A
C
A
A
T
A
T
C
C
T
T
T
T
G
A
A
G
A
C
C
A
T
A
A
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C
C
A
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C
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C
A
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C
T
A
G
A
A
C
T
T
A
T
C
A
A
A
C
C
C
T
T
T
T
G
T
G
A
A
T
0.107632
0.035225
0.062622
0.066536
0.039139
0.02544
0.001957
0.029354
0.050881
0.015656
0.031311
0.048924
0.031311
0.029354
0.041096
0.021526
0.027397
0.027397
0.015656
0.001957
0.003914
0
0.021526
0.015656
0.046967
0.015656
0.023483
0.011742
0.023483
0.023483
0.074364
0.029354
1
10,058
T
G
C
A
C
A
A
T
A
T
C
C
T
T
T
T
G
A
A
G
A
C
C
A
T
A
A
C
C
C
A
C
C
A
C
A
G
C
T
A
G
A
A
C
T
T
A
T
C
A
A
A
C
C
C
T
T
T
T
G
T
G
A
A
G
A
0.109589
0.035225
0.062622
0.066536
0.039139
0.02544
0.001957
0.029354
0.050881
0.015656
0.031311
0.048924
0.031311
0.029354
0.041096
0.021526
0.027397
0.027397
0.015656
0.001957
0.003914
0
0.021526
0.015656
0.04501
0.015656
0.023483
0.011742
0.023483
0.023483
0.074364
0.029354
1
10,059
A
T
T
G
T
C
A
T
C
T
T
C
A
C
T
T
A
G
C
C
A
T
T
G
G
T
C
A
A
G
A
T
C
T
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C
A
C
A
A
A
A
G
G
G
T
T
T
G
A
T
A
A
G
T
T
C
T
A
G
C
T
G
T
G
A
0.123288
0.039139
0.060665
0.060665
0.041096
0.02544
0.001957
0.029354
0.054795
0.013699
0.027397
0.041096
0.031311
0.027397
0.04501
0.021526
0.027397
0.029354
0.017613
0.001957
0.003914
0
0.021526
0.015656
0.048924
0.015656
0.023483
0.009785
0.023483
0.021526
0.068493
0.027397
1
10,060
G
A
T
T
G
T
C
A
T
C
T
T
C
A
C
T
T
A
G
C
C
A
T
T
G
G
T
C
A
A
G
A
T
C
T
T
C
A
C
A
A
A
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G
G
G
T
T
T
G
A
T
A
A
G
T
T
C
T
A
G
C
T
G
T
A
0.123288
0.039139
0.060665
0.060665
0.041096
0.02544
0.001957
0.029354
0.054795
0.013699
0.027397
0.041096
0.031311
0.027397
0.04501
0.021526
0.027397
0.029354
0.017613
0.001957
0.003914
0
0.021526
0.015656
0.048924
0.015656
0.023483
0.009785
0.02544
0.021526
0.066536
0.027397
1
10,061
C
A
A
A
C
C
C
T
T
T
T
G
T
G
A
A
G
A
T
C
T
T
G
A
C
C
A
A
T
G
G
C
T
A
A
G
T
G
A
A
G
A
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G
A
C
A
A
T
C
A
T
G
T
T
G
C
A
G
C
A
A
T
T
C
C
0.127202
0.041096
0.056751
0.062622
0.041096
0.02544
0.001957
0.029354
0.048924
0.013699
0.029354
0.041096
0.029354
0.027397
0.04501
0.021526
0.029354
0.029354
0.017613
0.001957
0.003914
0
0.021526
0.015656
0.050881
0.013699
0.023483
0.009785
0.02544
0.021526
0.064579
0.029354
1
10,062
A
T
G
G
C
T
A
A
G
T
G
A
A
G
A
T
G
A
C
A
A
T
C
A
T
G
T
T
G
C
A
G
C
A
A
T
T
C
A
C
T
G
T
A
A
A
G
C
T
G
G
A
A
A
G
G
G
A
C
G
A
A
C
T
G
G
0.125245
0.039139
0.056751
0.062622
0.043053
0.027397
0.001957
0.027397
0.04501
0.013699
0.031311
0.04501
0.029354
0.027397
0.046967
0.023483
0.029354
0.029354
0.017613
0.001957
0.003914
0
0.015656
0.015656
0.046967
0.013699
0.023483
0.009785
0.02544
0.02544
0.064579
0.031311
1
10,063
T
A
A
G
T
G
A
A
G
A
T
G
A
C
A
A
T
C
A
T
G
T
T
G
C
A
G
C
A
A
T
T
C
A
C
T
G
T
A
A
A
G
C
T
G
G
A
A
A
G
G
G
A
C
G
A
A
C
T
G
G
T
G
T
A
G
0.127202
0.037182
0.054795
0.064579
0.043053
0.027397
0.001957
0.027397
0.04501
0.011742
0.031311
0.048924
0.029354
0.027397
0.046967
0.023483
0.029354
0.029354
0.017613
0.001957
0.003914
0
0.015656
0.015656
0.046967
0.013699
0.023483
0.009785
0.02544
0.02544
0.062622
0.031311
1
10,064
T
T
A
C
A
C
C
A
G
T
T
C
G
T
C
C
C
T
T
T
C
C
A
G
C
T
T
T
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C
A
G
T
G
A
A
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T
G
C
T
G
C
A
A
C
A
T
G
A
T
T
G
T
C
A
T
C
T
T
C
A
C
T
T
C
0.127202
0.037182
0.054795
0.064579
0.043053
0.027397
0.001957
0.027397
0.04501
0.011742
0.031311
0.050881
0.029354
0.027397
0.046967
0.023483
0.029354
0.029354
0.017613
0.001957
0.003914
0
0.015656
0.015656
0.046967
0.013699
0.021526
0.009785
0.02544
0.02544
0.062622
0.031311
1
10,065
G
T
G
A
A
G
A
T
G
A
C
A
A
T
C
A
T
G
T
T
G
C
A
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C
A
A
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T
C
A
C
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T
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A
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C
T
G
G
A
A
A
G
G
G
A
C
G
A
A
C
T
G
G
T
G
T
A
A
T
G
C
0.127202
0.037182
0.054795
0.062622
0.04501
0.027397
0.001957
0.027397
0.04501
0.011742
0.031311
0.050881
0.029354
0.027397
0.04501
0.023483
0.029354
0.029354
0.017613
0.001957
0.003914
0
0.015656
0.015656
0.046967
0.013699
0.021526
0.009785
0.02544
0.027397
0.062622
0.031311
1
10,066
G
A
A
G
A
T
G
A
C
A
A
T
C
A
T
G
T
T
G
C
A
G
C
A
A
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T
C
A
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C
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G
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G
G
A
C
G
A
A
C
T
G
G
T
G
T
A
A
T
G
A
T
G
0.127202
0.037182
0.054795
0.064579
0.04501
0.027397
0.001957
0.027397
0.04501
0.011742
0.031311
0.048924
0.029354
0.027397
0.046967
0.023483
0.029354
0.029354
0.017613
0.001957
0.003914
0
0.015656
0.015656
0.046967
0.013699
0.021526
0.009785
0.02544
0.02544
0.062622
0.031311
1
10,067
A
A
T
A
T
G
C
A
C
A
T
A
T
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A
G
T
G
A
A
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T
G
C
T
G
C
A
A
C
A
T
G
A
C
0.121331
0.037182
0.054795
0.062622
0.04501
0.027397
0.001957
0.027397
0.043053
0.011742
0.031311
0.054795
0.029354
0.029354
0.046967
0.023483
0.029354
0.029354
0.017613
0.001957
0.003914
0
0.015656
0.015656
0.04501
0.013699
0.021526
0.009785
0.02544
0.027397
0.062622
0.033268
1
10,068
T
A
A
A
T
A
T
G
C
A
C
A
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A
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A
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A
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A
T
G
0.121331
0.037182
0.054795
0.062622
0.04501
0.027397
0.001957
0.027397
0.041096
0.011742
0.031311
0.054795
0.031311
0.031311
0.046967
0.023483
0.029354
0.029354
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.04501
0.013699
0.021526
0.009785
0.02544
0.027397
0.062622
0.033268
1
10,069
A
T
A
A
A
T
A
T
G
C
A
C
A
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A
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A
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T
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C
T
G
C
A
A
C
A
T
0.121331
0.037182
0.054795
0.062622
0.046967
0.027397
0.001957
0.027397
0.041096
0.011742
0.031311
0.054795
0.031311
0.031311
0.046967
0.023483
0.027397
0.029354
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.04501
0.013699
0.021526
0.009785
0.02544
0.027397
0.062622
0.033268
1
10,070
A
T
A
A
A
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A
T
G
C
A
C
A
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T
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C
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A
A
0.121331
0.037182
0.054795
0.062622
0.046967
0.027397
0.001957
0.027397
0.041096
0.011742
0.031311
0.054795
0.031311
0.031311
0.046967
0.023483
0.027397
0.029354
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.04501
0.013699
0.021526
0.009785
0.02544
0.027397
0.062622
0.033268
1
10,071
T
T
G
C
A
G
C
A
A
T
T
C
A
C
T
G
T
A
A
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A
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A
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G
C
A
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A
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T
T
A
T
T
A
G
0.123288
0.039139
0.054795
0.062622
0.046967
0.027397
0.001957
0.027397
0.041096
0.011742
0.031311
0.054795
0.031311
0.031311
0.046967
0.023483
0.027397
0.027397
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.04501
0.013699
0.021526
0.009785
0.023483
0.027397
0.062622
0.033268
1
10,072
G
T
A
A
T
A
A
A
T
A
T
G
C
A
C
A
T
A
T
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A
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C
T
T
T
A
C
A
G
T
G
A
A
T
T
G
C
T
G
C
A
T
0.125245
0.039139
0.054795
0.062622
0.046967
0.027397
0.001957
0.027397
0.041096
0.011742
0.031311
0.054795
0.031311
0.031311
0.046967
0.023483
0.027397
0.027397
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.043053
0.013699
0.021526
0.009785
0.023483
0.027397
0.062622
0.033268
1
10,073
G
T
A
A
T
A
A
A
T
A
T
G
C
A
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A
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C
T
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G
A
A
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T
G
C
T
G
C
A
G
0.125245
0.039139
0.054795
0.062622
0.046967
0.027397
0.001957
0.027397
0.041096
0.011742
0.031311
0.054795
0.031311
0.031311
0.046967
0.023483
0.027397
0.027397
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.043053
0.013699
0.021526
0.009785
0.023483
0.027397
0.062622
0.033268
1
10,074
A
G
C
A
A
T
T
C
A
C
T
G
T
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C
T
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T
G
C
A
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A
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A
T
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A
C
A
T
C
T
0.125245
0.039139
0.054795
0.060665
0.046967
0.027397
0.001957
0.027397
0.041096
0.011742
0.031311
0.054795
0.031311
0.031311
0.048924
0.023483
0.027397
0.027397
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.043053
0.013699
0.021526
0.009785
0.021526
0.027397
0.062622
0.035225
1
10,075
C
C
C
G
A
T
G
T
A
A
T
A
A
A
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A
T
G
C
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C
A
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C
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A
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T
G
A
A
T
T
T
0.125245
0.039139
0.054795
0.060665
0.048924
0.027397
0.001957
0.02544
0.041096
0.011742
0.031311
0.054795
0.031311
0.033268
0.048924
0.023483
0.02544
0.02544
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.043053
0.013699
0.021526
0.009785
0.021526
0.029354
0.062622
0.035225
1
10,076
A
A
A
T
T
T
G
C
C
C
C
G
A
T
G
T
A
A
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C
G
T
C
C
C
T
T
T
C
C
A
G
C
T
T
T
A
C
C
0.121331
0.037182
0.052838
0.060665
0.050881
0.027397
0.001957
0.02544
0.039139
0.011742
0.031311
0.060665
0.031311
0.035225
0.048924
0.023483
0.02544
0.02544
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.041096
0.013699
0.021526
0.009785
0.021526
0.031311
0.062622
0.035225
1
10,077
A
A
G
C
T
G
G
A
A
A
G
G
G
A
C
G
A
A
C
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T
A
C
A
T
C
G
G
G
G
C
A
A
A
T
T
T
T
T
A
C
0.119374
0.037182
0.052838
0.060665
0.050881
0.027397
0.001957
0.02544
0.039139
0.011742
0.031311
0.064579
0.031311
0.035225
0.048924
0.023483
0.02544
0.02544
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.041096
0.013699
0.021526
0.009785
0.021526
0.033268
0.058708
0.035225
1
10,078
T
T
A
A
A
A
A
T
T
T
G
C
C
C
C
G
A
T
G
T
A
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C
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C
A
G
T
T
C
G
T
C
C
C
T
T
T
C
C
A
G
C
T
T
0.117417
0.037182
0.052838
0.060665
0.052838
0.027397
0.001957
0.02544
0.039139
0.011742
0.031311
0.064579
0.031311
0.035225
0.048924
0.023483
0.02544
0.02544
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.041096
0.013699
0.021526
0.009785
0.021526
0.033268
0.058708
0.035225
1
10,079
T
T
A
A
A
A
A
T
T
T
G
C
C
C
C
G
A
T
G
T
A
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C
A
G
T
T
C
G
T
C
C
C
T
T
T
C
C
A
G
C
T
A
0.117417
0.037182
0.052838
0.060665
0.052838
0.027397
0.001957
0.02544
0.039139
0.011742
0.031311
0.064579
0.031311
0.035225
0.048924
0.023483
0.02544
0.02544
0.017613
0.001957
0.003914
0
0.015656
0.013699
0.041096
0.013699
0.021526
0.009785
0.021526
0.033268
0.058708
0.035225
1
10,080
A
A
T
T
T
T
T
A
A
A
G
G
C
A
C
A
A
G
A
G
G
C
C
C
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A
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A
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G
G
A
C
C
A
G
A
G
A
C
A
A
A
A
A
G
G
T
A
C
0.109589
0.031311
0.048924
0.062622
0.052838
0.02544
0.001957
0.027397
0.037182
0.011742
0.029354
0.066536
0.035225
0.041096
0.046967
0.029354
0.02544
0.02544
0.017613
0.001957
0.003914
0
0.015656
0.015656
0.043053
0.015656
0.017613
0.009785
0.021526
0.031311
0.050881
0.046967
1
10,081
T
T
A
C
C
T
T
T
T
T
G
T
C
T
C
T
G
G
T
C
C
T
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C
C
C
A
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A
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C
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C
C
T
C
T
T
G
T
G
C
C
T
T
T
A
A
A
A
A
T
C
0.109589
0.031311
0.048924
0.060665
0.052838
0.02544
0.001957
0.027397
0.037182
0.011742
0.029354
0.066536
0.035225
0.041096
0.046967
0.029354
0.02544
0.02544
0.017613
0.001957
0.003914
0
0.015656
0.015656
0.043053
0.015656
0.017613
0.009785
0.021526
0.031311
0.052838
0.046967
1
10,082
C
A
C
A
T
A
G
C
G
C
C
T
C
T
G
A
C
T
G
G
G
A
A
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T
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C
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G
A
C
A
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A
A
A
A
A
A
A
A
G
A
G
A
A
G
C
C
A
A
A
T
T
T
0.086106
0.041096
0.035225
0.082192
0.041096
0.019569
0.001957
0.033268
0.037182
0.021526
0.019569
0.07045
0.02544
0.041096
0.039139
0.019569
0.031311
0.037182
0.009785
0.001957
0.001957
0.009785
0.027397
0.019569
0.048924
0.011742
0.015656
0.009785
0.029354
0.023483
0.07045
0.037182
1
10,083
C
A
C
A
T
A
G
C
G
C
C
T
C
T
G
A
C
T
G
G
G
A
A
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T
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C
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A
C
A
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A
A
A
A
A
A
A
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G
A
G
A
A
G
C
C
A
A
A
T
T
G
0.086106
0.041096
0.035225
0.082192
0.041096
0.019569
0.001957
0.033268
0.037182
0.021526
0.019569
0.07045
0.02544
0.041096
0.039139
0.019569
0.031311
0.037182
0.009785
0.001957
0.001957
0.009785
0.027397
0.019569
0.048924
0.011742
0.015656
0.009785
0.029354
0.023483
0.07045
0.037182
1
10,084
A
C
A
C
A
T
A
G
C
G
C
C
T
C
T
G
A
C
T
G
G
G
A
A
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A
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A
A
A
A
A
A
A
A
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A
G
A
A
G
C
C
A
A
A
T
A
0.086106
0.041096
0.035225
0.082192
0.041096
0.019569
0.001957
0.033268
0.039139
0.021526
0.019569
0.07045
0.02544
0.041096
0.039139
0.019569
0.031311
0.037182
0.009785
0.001957
0.001957
0.007828
0.027397
0.019569
0.048924
0.011742
0.015656
0.009785
0.029354
0.023483
0.07045
0.037182
1
10,085
A
T
A
A
T
A
C
A
C
A
T
A
G
C
G
C
C
T
C
T
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A
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A
A
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G
A
C
A
G
A
A
A
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A
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A
A
G
A
G
A
A
G
C
C
0.086106
0.039139
0.035225
0.082192
0.039139
0.019569
0.001957
0.035225
0.039139
0.019569
0.019569
0.074364
0.02544
0.041096
0.039139
0.019569
0.029354
0.037182
0.009785
0.001957
0.001957
0.005871
0.029354
0.019569
0.048924
0.013699
0.015656
0.009785
0.029354
0.023483
0.07045
0.037182
1
10,086
G
T
A
G
C
T
A
T
A
A
T
A
A
T
A
C
A
C
A
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T
C
C
C
T
G
G
T
G
G
A
C
A
G
A
A
A
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G
0.086106
0.039139
0.035225
0.084149
0.037182
0.017613
0.001957
0.035225
0.041096
0.019569
0.017613
0.076321
0.02544
0.041096
0.037182
0.017613
0.031311
0.037182
0.009785
0.001957
0.001957
0.005871
0.029354
0.019569
0.052838
0.011742
0.015656
0.009785
0.029354
0.023483
0.07045
0.037182
1
10,087
G
G
T
A
G
C
T
A
T
A
A
T
A
A
T
A
C
A
C
A
T
A
G
C
G
C
C
T
C
T
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A
C
T
G
G
G
A
A
T
A
G
T
T
A
C
T
C
C
C
T
G
G
T
G
G
A
C
A
G
A
A
A
A
A
A
0.086106
0.039139
0.035225
0.084149
0.037182
0.017613
0.001957
0.035225
0.041096
0.021526
0.017613
0.076321
0.02544
0.041096
0.035225
0.017613
0.031311
0.037182
0.009785
0.001957
0.001957
0.005871
0.029354
0.019569
0.052838
0.011742
0.015656
0.009785
0.029354
0.023483
0.07045
0.037182
1
10,088
T
T
T
T
C
T
G
T
C
C
A
C
C
A
G
G
G
A
G
T
A
A
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T
A
T
T
C
C
C
A
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T
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C
T
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G
T
G
T
A
T
T
A
T
T
A
T
A
G
C
T
A
C
C
T
A
0.086106
0.039139
0.035225
0.084149
0.037182
0.017613
0.001957
0.035225
0.041096
0.021526
0.017613
0.076321
0.02544
0.041096
0.035225
0.017613
0.031311
0.037182
0.009785
0.001957
0.001957
0.005871
0.029354
0.019569
0.052838
0.011742
0.017613
0.009785
0.029354
0.023483
0.07045
0.035225
1
10,089
T
T
T
T
C
T
G
T
C
C
A
C
C
A
G
G
G
A
G
T
A
A
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T
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T
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C
C
C
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T
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C
G
C
T
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T
G
T
G
T
A
T
T
A
T
T
A
T
A
G
C
T
A
C
C
T
G
0.086106
0.039139
0.035225
0.084149
0.037182
0.017613
0.001957
0.035225
0.041096
0.021526
0.017613
0.076321
0.02544
0.041096
0.035225
0.017613
0.031311
0.037182
0.009785
0.001957
0.001957
0.005871
0.029354
0.019569
0.052838
0.011742
0.017613
0.009785
0.029354
0.023483
0.07045
0.035225
1
10,090
T
T
T
C
T
G
T
C
C
A
C
C
A
G
G
G
A
G
T
A
A
C
T
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T
T
C
C
C
A
G
T
C
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G
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T
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T
G
T
A
T
T
A
T
T
A
T
A
G
C
T
A
C
C
T
G
A
0.086106
0.039139
0.035225
0.084149
0.037182
0.017613
0.001957
0.035225
0.041096
0.021526
0.017613
0.076321
0.02544
0.043053
0.035225
0.017613
0.031311
0.037182
0.009785
0.001957
0.001957
0.005871
0.029354
0.019569
0.050881
0.011742
0.017613
0.009785
0.029354
0.023483
0.07045
0.035225
1