title large_stringlengths 0 979 | abstract large_stringlengths 1 94.7k | doi large_stringlengths 0 71 | pmid int64 21 38.1M | mesh_terms large_stringlengths 0 1.47k | journal large_stringlengths 1 239 | pubdate int16 1.97k 2.02k | chemical_list large_stringlengths 0 1.47k |
|---|---|---|---|---|---|---|---|
A longitudinal study to monitor chloroquine-resistant P. falciparum malaria in Bokajan and Manja PHC areas of Karbi Anglong District, Assam. | In-vivo as well as in-vitro studies were carried out at regular intervals from 1979 to 1988 to monitor chloroquine resistance in P. falciparum in Bokajan and Manja PHC of Karbi Anglong district, Assam. The results showed no significant change in resistance status in the area. Intensified antivector measures, withdrawal... | 1,286,733 | D000818:Animals; D002738:Chloroquine; D004351:Drug Resistance; D006801:Humans; D007194:India; D008137:Longitudinal Studies; D016778:Malaria, Falciparum; D010963:Plasmodium falciparum | Indian journal of malariology | 1,992 | D002738:Chloroquine | |
A polymer with a benzo[2,1-b;3,4-b']dithiophene moiety for photovoltaic applications. | The characterization of a benzo[2,1-b;3,4-b']dithiophene containing conjugated polymer (PBTT) is demonstrated, with regard to its photovoltaic performance. X-ray diffraction measurements reveal that the thermal treatment results in an increased crystallinity within the PBTT:[70]PCBM network and subsequent spatial rearr... | 10.1002/cssc.200900161 | 19,904,801 | D001562:Benzimidazoles; D004563:Electrochemistry; D010777:Photochemistry; D011108:Polymers; D012993:Solar Energy; D013499:Surface Properties; D013841:Thiazepines; D013876:Thiophenes; D014961:X-Ray Diffraction | ChemSusChem | 2,010 | D001562:Benzimidazoles; D011108:Polymers; D013841:Thiazepines; D013876:Thiophenes; C553050:poly(2,7-(benzo(2,1-b-3,4-b')dithiophene)-alt-2,2'-(3,3'-didodecyl-5,5'-bithiophenyl)) |
Knockdown of CEBPβ by RNAi in porcine granulosa cells resulted in S phase cell cycle arrest and decreased progesterone and estradiol synthesis. | Cultured ovarian granulosa cells (GCs) are essential models to study molecular mechanisms of gene regulation during folliculogenesis. CCAAT enhancer binding proteins β (CEBPβ) has been identified in the ovary and is critical for follicular growth, ovulation and luteinization in mice. In the present study, hormonal trea... | 24,607,812 | D000818:Animals; D017209:Apoptosis; D015153:Blotting, Western; D022782:CCAAT-Enhancer-Binding Protein-beta; D059447:Cell Cycle Checkpoints; D049109:Cell Proliferation; D002478:Cells, Cultured; D002786:Cholesterol Side-Chain Cleavage Enzyme; D006063:Chorionic Gonadotropin; D004797:Enzyme-Linked Immunosorbent Assay; D004... | The Journal of steroid biochemistry and molecular biology | 2,014 | D022782:CCAAT-Enhancer-Binding Protein-beta; D006063:Chorionic Gonadotropin; D012333:RNA, Messenger; D034741:RNA, Small Interfering; D012102:Reproductive Control Agents; D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone; D002786:Cholesterol Side-Chain Cleavage Enzyme | |
The Influence of Living Situations on Family Therapy Involvement Among Youth Adjudicated of a Sexual Crime. | Clinical and research professionals working with youth who have sexually offended have increasingly advocated for community-based care. However, other scholars have noted the appropriateness of residential placements for many youth. Research is inconclusive concerning the degree to which youth with sexually harmful beh... | 10.1177/0306624X14556252 | 25,413,951 | D000293:Adolescent; D005195:Family Relations; D005196:Family Therapy; D005260:Female; D006801:Humans; D008297:Male; D012742:Sex Offenses; D014481:United States | International journal of offender therapy and comparative criminology | 2,016 | |
Tissue engineering and tissue repair in immunocompetent animals: tissue construction and repair. | Tissue engineering can regenerate autologous tissue using a biodegradable scaffold and in vitro expanded cells derived from small biopsy samples, and thus may have great potential for tissue repair and reconstruction in plastic and reconstructive surgery. As an important step towards a clinical application, research wo... | 10.1055/s-2007-965329 | 17,602,376 | D000818:Animals; D016025:Bone Transplantation; D002356:Cartilage; D002645:Chickens; D004285:Dogs; D007121:Immunocompetence; D019651:Plastic Surgery Procedures; D012756:Sheep; D013552:Swine; D013710:Tendons; D023822:Tissue Engineering | Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... | 2,007 | |
Stem cell therapy for type 1 diabetes mellitus. | The use of stem cells in regenerative medicine holds great promise for the cure of many diseases, including type 1 diabetes mellitus (T1DM). Any potential stem-cell-based cure for T1DM should address the need for beta-cell replacement, as well as control of the autoimmune response to cells which express insulin. The ex... | 10.1038/nrendo.2009.274 | 20,173,775 | D002454:Cell Differentiation; D003922:Diabetes Mellitus, Type 1; D006801:Humans; D050417:Insulin-Secreting Cells; D008954:Models, Biological; D015398:Signal Transduction; D033581:Stem Cell Transplantation; D013234:Stem Cells | Nature reviews. Endocrinology | 2,010 | |
Estimating the Effects of Head Start on Parenting and Child Maltreatment. | We examine the effects of Head Start participation on parenting and child maltreatment in a large and diverse sample of low-income families in large U.S. cities (N = 2,807), using rich data from the Fragile Families and Child Wellbeing Study (FFCWS). To address the issue of selection bias, we employ several analytic ap... | 10.1016/j.childyouth.2011.03.008 | 23,788,823 | Children and youth services review | 2,013 | ||
High risk of malnutrition is associated with low muscle mass in older hospitalized patients - a prospective cohort study. | BACKGROUND
Malnutrition, low muscle strength and muscle mass are highly prevalent in older hospitalized patients and associated with adverse outcomes. Malnutrition may be a risk factor for developing low muscle mass. We aimed to investigate the association between the risk of malnutrition and 1) muscle strength and mus... | 10.1186/s12877-017-0505-5 | 28,583,070 | D000368:Aged; D015331:Cohort Studies; D005260:Female; D015577:Geriatric Assessment; D018737:Hand Strength; D006760:Hospitalization; D006801:Humans; D008297:Male; D044342:Malnutrition; D018482:Muscle, Skeletal; D009426:Netherlands; D015596:Nutrition Assessment; D016017:Odds Ratio; D015995:Prevalence; D011446:Prospective... | BMC geriatrics | 2,017 | |
Selective subcellular localization of cations with variants of the potassium (pyro)antimonate technique. | Fixation of rat parotid with an unbuffered osmium tetroxide solution containing nearly saturated potassium (pyro)antimonate resulted in abundant deposition of cation-antimonate precipatates in acinar cells. Altering the antimonate concentration, including buffers or chelators in the solution or changing the primary fix... | 10.1177/23.8.51037 | 51,037 | D000641:Ammonia; D000818:Animals; D000965:Antimony; D002118:Calcium; D002413:Cations, Divalent; D002414:Cations, Monovalent; D005069:Evaluation Studies as Topic; D006651:Histocytochemistry; D006657:Histones; D006863:Hydrogen-Ion Concentration; D008274:Magnesium; D008854:Microscopy, Electron; D009928:Organ Specificity; ... | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society | 1,975 | D002413:Cations, Divalent; D002414:Cations, Monovalent; D006657:Histones; D000641:Ammonia; D000965:Antimony; D012964:Sodium; D008274:Magnesium; D002118:Calcium |
Affinity binding phenomena of DNA onto apatite crystals. | The effect of DNA on the crystal growth of hydroxyapatite (HAp) and its morphology was examined. X-ray diffraction patterns of DNA-containing apatites showed typical apatitic features. However, crystal growth was greatly inhibited in the presence of DNA during synthesis; particularly, the crystallinity in the a-axis di... | 10.1016/s0142-9612(00)00433-6 | 11,516,076 | D000818:Animals; D001665:Binding Sites; D001672:Biocompatible Materials; D003460:Crystallization; D018360:Crystallography, X-Ray; D004247:DNA; D006882:Hydroxyapatites; D009682:Magnetic Resonance Spectroscopy; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D008956:Models, Chemical; D012995:Solubility... | Biomaterials | 2,001 | D001672:Biocompatible Materials; D006882:Hydroxyapatites; D004247:DNA |
Serum cholesterol levels in Puerto Rican volunteer blood donors. | The blood samples of four hundred and fifty eight healthy volunteer blood donors were analyzed to determine their serum lipid profile. Based on these lipoprotein analyses, it was concluded that approximately 12% of the sampled population was in a high risk group for coronary heart disease. | 2,765,045 | D001782:Blood Donors; D002784:Cholesterol; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D003327:Coronary Disease; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia; D008297:Male; D011647:Puerto Rico; D012016:Reference Values; D012307:Risk Factors | Boletin de la Asociacion Medica de Puerto Rico | 1,989 | D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D002784:Cholesterol | |
Diet of eared doves (Zenaida auriculata, Aves, Columbidae) in a sugar-cane colony in South-eastern Brazil. | Farmers in the Paranapanema Valley (São Paulo, Brazil) have reported problems with flocks of Eared Doves (Zenaida auriculata) eating sprouting soybeans. In this region these birds breed colonially in sugar-cane, and eat four crop seeds, using 70% of the dry weight, in the following order of importance: maize, wheat, ri... | 10.1590/s1519-69842001000400015 | 12,071,322 | D000818:Animals; D001938:Brazil; D001947:Breeding; D010856:Columbidae; D018548:Cotyledon; D018556:Crops, Agricultural; D004032:Diet; D002523:Edible Grain; D012639:Seeds; D013025:Glycine max | Brazilian journal of biology = Revista brasleira de biologia | 2,001 | |
What do mothers of young children think of community pharmacists? A descriptive survey. | AIM
To discover the attitudes of mothers of young children towards community pharmacists, and mothers' use of community pharmacies for childhood illnesses
OBJECTIVES
To discover how frequently mothers visit pharmacies; for which childhood complaints they tend to consult a pharmacist first, rather than other health pr... | 15,341,374 | D000328:Adult; D000367:Age Factors; D001294:Attitude to Health; D002669:Child Welfare; D002675:Child, Preschool; D003157:Community Pharmacy Services; D003376:Counseling; D004739:England; D005260:Female; D017144:Focus Groups; D006266:Health Education; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D00829... | The journal of family health care | 2,004 | ||
Mothers' parenting self-appraisals: the contribution of perceived infant temperament. | To learn how a mother's perception of her infant's temperament contributes to her appraisal of her parenting and of her problem-solving competence during the first 3 months postpartum, we explored a conceptual model, including infant gender and maternal attributes (education and parity) and the personal and social cont... | 10.1002/nur.4770170509 | 8,090,949 | D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009034:Mother-Child Relations; D009035:Mothers; D016487:Parenting; D011340:Problem Solving; D002666:Psychology, Child; D012649:Self Concept; D011795:Surveys and Questionnaires; D013694:Temperament | Research in nursing & health | 1,994 | |
Impaired IL-4 phosphorylation of STAT6 in EBV transformed B-cells. | BACKGROUND
The Interleukin-4 signal transducer and activator of transcription 6 (IL-4-STAT6) signaling pathway plays a pivotal role in regulation of gene transcription. We have previously identified a defective STAT6 activational phenotype in response to IL-4 in patients from our familial Inflammatory Bowel Disease reg... | 10.1016/j.jss.2009.01.004 | 19,540,524 | D001402:B-Lymphocytes; D015153:Blotting, Western; D002460:Cell Line; D002461:Cell Line, Transformed; D004854:Herpesvirus 4, Human; D006801:Humans; D007371:Interferon-gamma; D015847:Interleukin-4; D053613:Janus Kinase 1; D053616:Janus Kinase 3; D008214:Lymphocytes; D010766:Phosphorylation; D019948:Receptors, Interleukin... | The Journal of surgical research | 2,010 | D019948:Receptors, Interleukin-4; D050800:STAT6 Transcription Factor; C494101:STAT6 protein, human; D015847:Interleukin-4; D007371:Interferon-gamma; C507904:JAK1 protein, human; D053613:Janus Kinase 1; D053616:Janus Kinase 3 |
Phylogeographic analysis of a temperate-deciduous forest restricted plant (Bupleurum longiradiatum Turcz.) reveals two refuge areas in China with subsequent refugial isolation promoting speciation. | This study investigates the influence of climate-induced oscillations and complicated geological conditions on the evolutionary processes responsible for species formation in presently fragmented temperate forest habitats, located in continental East Asia. In addition to this, we also investigate the heavily debated is... | 23,624,194 | D005075:Biological Evolution; D029972:Bupleurum; D002681:China; D002980:Climate; D018744:DNA, Plant; D017753:Ecosystem; D019143:Evolution, Molecular; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D006239:Haplotypes; D008969:Molecular Sequence Data; D010641:Phenotype; D010802:Phylogeny... | Molecular phylogenetics and evolution | 2,013 | D018744:DNA, Plant | |
The Relationship Between Personality Traits and Coping Styles Among First-Time and Recurrent Prisoners in Poland. | Individuals with certain personality traits employ adaptive coping strategies. Little research, however, has examined coping strategies among incarcerated individuals. A cross-sectional study was conducted among 465 males who served time in five different prisons in Poland. We examined the relationship between the Big ... | 10.3389/fpsyg.2019.02969 | 32,010,025 | Frontiers in psychology | 2,019 | ||
On employing a translationally controlled tumor protein-derived protein transduction domain analog for transmucosal delivery of drugs. | Protein transduction domains (PTDs) are recognized as promising vehicles for the delivery of macromolecular drugs. We have previously shown that a region in the N-terminus (residues 1-10) of translationally controlled tumor protein (TCTP) contains a PTD (TCTP-PTD), MIIYRDLISH, which can serve as a vehicle for the deliv... | 23,791,976 | D000281:Administration, Intranasal; D000818:Animals; D014408:Biomarkers, Tumor; D001786:Blood Glucose; D003921:Diabetes Mellitus, Experimental; D016503:Drug Delivery Systems; D007004:Hypoglycemic Agents; D007328:Insulin; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009297:Nasal Mucosa; D009842:Oligopeptide... | Journal of controlled release : official journal of the Controlled Release Society | 2,013 | D014408:Biomarkers, Tumor; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D009842:Oligopeptides; C000715648:Tpt1 protein, mouse; D000090324:Tumor Protein, Translationally-Controlled 1 | |
Variations in the fuel structure control the rate of the back and forth motions of a chemically fuelled molecular switch. | This work deals with the use of 2-cyano-2-arylpropanoic acids as chemical fuels for an acid-base operated molecular switch that consists of a Sauvage-type catenand composed of two identical macrocycles incorporating a phenanthroline unit. When used as a base promoter of the decarboxylation of propanoic acid derivatives... | 10.1039/c7sc04123c | 29,629,086 | Chemical science | 2,018 | ||
A fast algorithm for computing inbreeding coefficients in large populations. | Inbreeding coefficients of animals are required in many genetic analyses of livestock records. A modification of Colleau's indirect algorithm to compute inbreeding coefficients in large populations is presented. With overlapping generations, the modified algorithm evaluated all progeny of each sire simultaneously in on... | 10.1111/j.1439-0388.2005.00538.x | 16,191,041 | D000465:Algorithms; D000818:Animals; D000829:Animals, Domestic; D001947:Breeding; D003198:Computer Simulation; D005828:Genetics, Population; D007178:Inbreeding | Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie | 2,005 | |
Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancer. | PURPOSE
To compare the efficacy and safety of docetaxel plus high-dose calcitriol (DN-101) to docetaxel plus prednisone in an open-label phase III trial.
PATIENTS AND METHODS
Nine hundred fifty-three men with metastatic castration-resistant prostate cancer (CRPC) were randomly assigned to Androgen-Independent Prostat... | 10.1200/JCO.2010.32.8815 | 21,483,004 | D000230:Adenocarcinoma; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols; D002117:Calcitriol; D000077143:Docetaxel; D019008:Drug Resistance, Neoplasm; D057239:Early Termination of Clinical Trials; D006801:Humans; D008297:Male; D011241:Prednisone; D011471:Prostatic Neoplasms; D016879:Salvage Therapy;... | Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 2,011 | D043823:Taxoids; D000077143:Docetaxel; D002117:Calcitriol; D011241:Prednisone |
Photodetachment-photoelectron spectroscopy of HS- x H2S and DS- x D2S: the transition states of the SH + H2S and SD + D2S reactions. | The transition state region for neutral hydrogen transfer reactions can be accessed by photodetachment of a stable negative ion with a geometry similar to that of the neutral transition state. In this work the SH + H(2)S and SD + D(2)S reactions are investigated by photodetachment-photoelectron spectroscopy of HS(-) x ... | 10.1039/b925941d | 20,556,264 | D003903:Deuterium; D041961:Deuterium Exchange Measurement; D006862:Hydrogen Sulfide; D013058:Mass Spectrometry; D056951:Photoelectron Spectroscopy | Physical chemistry chemical physics : PCCP | 2,010 | D003903:Deuterium; D006862:Hydrogen Sulfide |
Clinical efficacy and tolerability of an immune-stimulant(*) constituted by inactivated bacterial bodies in the prophylaxis of infectious episodes of airways: a double blind, placebo-controlled, randomized, multicentre study. | BACKGROUND
(Buccalin ®) is a Bacterial Lysates (BL) that belongs to a family of immune-stimulators, developed more than 30 years ago and it still has a role in the prophylaxis of Recurrent Respiratory Tract Infections (RRTI). However, original studies were conducted with an approach that does not seem to be aligned wit... | 10.1186/2049-6958-9-58 | 25,699,178 | Multidisciplinary respiratory medicine | 2,014 | ||
Targeted Melanoma Screening: Risk Self-Assessment and Skin Self-Examination Education Delivered During Mammography of Women. | BACKGROUND
Melanoma, which is the sixth most common cancer in women, is visible on the surface of the skin; therefore, self-screening (skin self-examination [SSE]) may be beneficial.
METHODS
A convenience sample of women undergoing mammography was sequentially assigned by week into this two-arm targeted melanoma scre... | 10.1093/jncics/pkz047 | 32,328,556 | JNCI cancer spectrum | 2,019 | ||
Effect of neutral lipids on fluidity of corpora lutea plasma membranes and the accessibility of LH/hCG receptor. | Porcine corpora lutea plasma membranes were treated with neutral lipids from hen egg yolk and a special mixture consisting of 70% neutral lipids, 20% phosphatidylcholine and 10% phosphatidylethanolamine. Membrane fluidity, as determined by fluorescence polarization of DPH, significantly increased already after 30 min o... | 8,773,492 | D000818:Animals; D002462:Cell Membrane; D002645:Chickens; D002784:Cholesterol; D006063:Chorionic Gonadotropin; D003338:Corpus Luteum; D004530:Egg Yolk; D005260:Female; D008055:Lipids; D008560:Membrane Fluidity; D008563:Membrane Lipids; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D011974:Receptors, ... | General physiology and biophysics | 1,995 | D006063:Chorionic Gonadotropin; D008055:Lipids; D008563:Membrane Lipids; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D011974:Receptors, LH; D002784:Cholesterol | |
Sleep Quality Effects Recovery After Total Knee Arthroplasty (TKA)--A Randomized, Double-Blind, Controlled Study. | This study examined the effects of sleep quality on early recovery after total knee arthroplasty. A total of 148 patients were randomized 1:1 to receive either zolpidem or placebo for 2 weeks. VAS pain scores (rest, ambulation and night), range of motion (ROM), total amount of opioid analgesics and antiemetics taken, p... | 26,344,094 | D000368:Aged; D000701:Analgesics, Opioid; D000932:Antiemetics; D019645:Arthroplasty, Replacement, Knee; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D007211:Indoles; D008297:Male; D008875:Middle Aged; D010149:Pain, Postoperative; D020250:Postoperative Nausea and Vomiting... | The Journal of arthroplasty | 2,015 | D000701:Analgesics, Opioid; D000932:Antiemetics; D006993:Hypnotics and Sedatives; D007211:Indoles; D011725:Pyridines; D000077526:Tropisetron; D000077334:Zolpidem | |
Influence of nonylphenol exposure on basic growth, development, and thyroid tissue structure in F1 male rats. | OBJECTIVE
Environmental endocrine disruptors (EEDs) with a weak ability to mimic estrogen have been associated with thyroid dysfunction. However, little is known about the effect of nonylphenol (NP), a well-known EED, on thyroid structure. The present study evaluates whether gestational and lactational exposure to NP i... | 10.7717/peerj.7039 | 31,245,175 | PeerJ | 2,019 | ||
Antibiotic guidelines and antibiotic use in adult bacterial meningitis in The Netherlands. | In The Netherlands, national guidelines for the treatment of adult patients with bacterial meningitis were introduced in October 1997. In 1998 we began a prospective, nationwide study to evaluate the compliance with these consensus-based guidelines. In addition, we evaluated whether the recommended initial treatment pr... | 10.1093/jac/49.4.661 | 11,909,840 | D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents; D004363:Drug Utilization; D006801:Humans; D016920:Meningitis, Bacterial; D008875:Middle Aged; D009426:Netherlands; D010349:Patient Compliance; D017410:Practice Guidelines as Topic | The Journal of antimicrobial chemotherapy | 2,002 | D000900:Anti-Bacterial Agents |
Characterization of Remitting and Relapsing Hyperglycemia in Post-Renal-Transplant Recipients. | BACKGROUND
Hyperglycemia following solid organ transplant is common among patients without pre-existing diabetes mellitus (DM). Post-transplant hyperglycemia can occur once or multiple times, which if continued, causes new-onset diabetes after transplantation (NODAT).
OBJECTIVE
To study if the first and recurrent inc... | 10.1371/journal.pone.0142363 | 26,551,468 | D015331:Cohort Studies; D005260:Female; D006801:Humans; D006943:Hyperglycemia; D007166:Immunosuppressive Agents; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012307:Risk Factors; D020123:Sirolimus; D013256:Steroids; D016559:Tacrolimus; D066027:Transplant Recipients | PloS one | 2,015 | D007166:Immunosuppressive Agents; D013256:Steroids; D020123:Sirolimus; D016559:Tacrolimus |
Promotion of noise-induced cochlear injury by toluene and ethylbenzene in the rat. | Ethylbenzene + toluene are known individually to have ototoxic potential at high exposure levels and with prolonged exposure times generally of 4-16 weeks. Both ethylbenzene + toluene are minor constituents of JP-8 jet fuel; this fuel has recently been determined to promote susceptibility to noise-induced hearing loss.... | 10.1093/toxsci/kfm109 | 17,517,824 | D000395:Air Pollutants, Occupational; D000818:Animals; D001309:Auditory Threshold; D001555:Benzene Derivatives; D001921:Brain; D003051:Cochlea; D005978:Glutathione; D018072:Hair Cells, Auditory, Outer; D006317:Hearing Loss, Noise-Induced; D008099:Liver; D008168:Lung; D008297:Male; D009622:Noise; D051381:Rats; D020318:R... | Toxicological sciences : an official journal of the Society of Toxicology | 2,007 | D000395:Air Pollutants, Occupational; D001555:Benzene Derivatives; D012997:Solvents; D014050:Toluene; D005978:Glutathione; C004912:ethylbenzene |
Association of Changes in Mood Status and Psychosocial Well-Being with Depression During Interferon-Based Treatment for Hepatitis C. | OBJECTIVE
The aims of this prospective study were to investigate temporal changes in mood status and distress level, as well as the development of depression, during pegylated interferon (PEG-IFN)-based treatment of patients with chronic hepatitis C (CHC). We also explored whether baseline demographic, psychiatric, and... | 10.4306/pi.2017.14.3.314 | 28,539,950 | Psychiatry investigation | 2,017 | ||
Protecting privacy of shared epidemiologic data without compromising analysis potential. | OBJECTIVE
Ensuring privacy of research subjects when epidemiologic data are shared with outside collaborators involves masking (modifying) the data, but overmasking can compromise utility (analysis potential). Methods of statistical disclosure control for protecting privacy may be impractical for individual researchers... | 10.1155/2012/421989 | 22,505,949 | D003219:Confidentiality; D004307:Dose-Response Relationship, Radiation; D004781:Environmental Exposure; D004812:Epidemiologic Methods; D006801:Humans; D033181:Information Dissemination; D007564:Japan; D009381:Neoplasms, Radiation-Induced; D054043:Nuclear Weapons; D012107:Research Design; D013223:Statistics as Topic; D0... | Journal of environmental and public health | 2,012 | |
Searching for targets for the systemic therapy of mesothelioma. | Malignant mesothelioma is an incurable disease associated with asbestos exposure arising in the pleural cavity and less frequently in the peritoneal cavity. Platinum-based combination chemotherapy with pemetrexed is the established standard of care. Multimodality approaches including surgery and radiotherapy are being ... | 10.1093/annonc/mdv101 | 25,722,383 | D000971:Antineoplastic Combined Chemotherapy Protocols; D002945:Cisplatin; D000068338:Everolimus; D051416:Focal Adhesion Protein-Tyrosine Kinases; D006801:Humans; D007167:Immunotherapy; D008175:Lung Neoplasms; D008654:Mesothelioma; D000086002:Mesothelioma, Malignant; D058990:Molecular Targeted Therapy; D000068437:Pemet... | Annals of oncology : official journal of the European Society for Medical Oncology | 2,015 | D000081082:Phosphoinositide-3 Kinase Inhibitors; D047428:Protein Kinase Inhibitors; D000068437:Pemetrexed; D000068338:Everolimus; D051416:Focal Adhesion Protein-Tyrosine Kinases; D058570:TOR Serine-Threonine Kinases; D002945:Cisplatin |
Sulfonyl Group Dance: A Tool for the Synthesis of 6-Azido-2-sulfonylpurine Derivatives. | 9-Substituted 2-chloro-6-sulfonylpurines provide 6-azido-2-sulfonylpurine derivatives with 61-83% yields when treated with sodium azide. Under optimized reaction conditions, the title compounds are obtained in a one-pot process, which involves a sequential treatment of 2,6-dichloropurines with a selected sodium sulfina... | 10.1021/acs.joc.9b03518 | 32,150,410 | The Journal of organic chemistry | 2,020 | ||
Burkholderia sp. Y4 inhibits cadmium accumulation in rice by increasing essential nutrient uptake and preferentially absorbing cadmium. | Microbial remediation of heavy metal-polluted soil is a commonly used method. Burkholderia sp. Y4, isolated from cadmium (Cd)-contaminated rice rhizosphere soil, was investigated for its direct and indirect effects on Cd accumulation in rice by SEM-EDS, FITR and sequencing analysis of the soil bacterial community. Burk... | 10.1016/j.chemosphere.2020.126603 | 32,240,860 | D001673:Biodegradation, Environmental; D001692:Biological Transport; D019117:Burkholderia; D002104:Cadmium; D007501:Iron; D019216:Metals, Heavy; D000078622:Nutrients; D012275:Oryza; D018517:Plant Roots; D058441:Rhizosphere; D012987:Soil; D012989:Soil Pollutants | Chemosphere | 2,020 | D019216:Metals, Heavy; D012987:Soil; D012989:Soil Pollutants; D002104:Cadmium; D007501:Iron |
Are early post-discharge physician contacts associated with 30-day psychiatric re-hospitalisation? A nationwide claims data based retrospective cohort study in Austria free of immortal time bias. | OBJECTIVES
Cost containment and quality of care considerations have increased research interest in the potential preventability of early re-hospitalisations. Various registry-based retrospective cohort studies on psychiatric re-hospitalisation have focused on the role of early post-discharge service contacts, but eithe... | 10.1002/mpr.1983 | 37,608,583 | International journal of methods in psychiatric research | 2,023 | ||
Cartilage-specific deficiency of clock gene Bmal1 accelerated articular cartilage degeneration in osteoarthritis by up-regulation of mTORC1 signaling. | Although a growing body of studies recently demonstrated that circadian clock gene Bmal1 plays an important role in cartilage development and homeostasis, evidence regarding the contribution of Bmal1 in articular cartilage of OA progression is still unclear. In the present study, we investigated the direct role of Bmal... | 10.1016/j.intimp.2023.109692 | 36,628,892 | D000818:Animals; D051379:Mice; D056930:ARNTL Transcription Factors; D002358:Cartilage, Articular; D019902:Chondrocytes; D008322:Mammals; D000076222:Mechanistic Target of Rapamycin Complex 1; D018345:Mice, Knockout; D010003:Osteoarthritis; D015398:Signal Transduction; D015854:Up-Regulation | International immunopharmacology | 2,023 | D056930:ARNTL Transcription Factors; D000076222:Mechanistic Target of Rapamycin Complex 1; C538961:Bmal1 protein, mouse |
Model for how type I restriction enzymes select cleavage sites in DNA. | Under appropriate conditions, digestion of phage T7 DNA by the type I restriction enzyme EcoK produces an orderly progression of discrete DNA fragments. All details of the fragmentation pattern can be explained on the basis of the known properties of type I enzymes, together with two further assumptions: (i) in the ATP... | 10.1073/pnas.85.13.4677 | 2,838,843 | D000255:Adenosine Triphosphate; D001426:Bacterial Proteins; D001483:Base Sequence; D001665:Binding Sites; D004247:DNA; D004262:DNA Restriction Enzymes; D004279:DNA, Viral; D015253:Deoxyribonucleases, Type I Site-Specific; D004926:Escherichia coli; D008954:Models, Biological; D013379:Substrate Specificity; D013604:T-Pha... | Proceedings of the National Academy of Sciences of the United States of America | 1,988 | D001426:Bacterial Proteins; D004279:DNA, Viral; D000255:Adenosine Triphosphate; D004247:DNA; D004262:DNA Restriction Enzymes; C029602:endodeoxyribonuclease EcoK; D015253:Deoxyribonucleases, Type I Site-Specific |
The effects of water availability on the life history of the desert snail,Trochoidea seetzeni : An experimental field manipulation. | In the Negev desert of Israel, the pulmonate land snailTrochoidea seetzeni is active, grows and reproduces in the month following the torrential winter rains. Thereafter, these snails estivate until the following year's rains. By experimental supplementation of water in the field, we examined the ability of these snail... | 10.1007/BF01875452 | 28,313,578 | Oecologia | 1,992 | ||
Preventive wire ligature of venae dorsales penis in radical retropubic surgery. | The method of preventive hemostasis as suggested by authors is capable of safely arresting the blood leakage into the operation field from spatium Retzii especially in radical retropubic surgery. Retropubic radical surgery requires haemostasis of the dorsal penile veins. In extracapsular prostatectomy, adequate haemost... | 8,711,362 | D006488:Hemostasis, Surgical; D006801:Humans; D008026:Ligation; D008297:Male; D010413:Penis; D011468:Prostatectomy; D014680:Veins | Sbornik lekarsky | 1,995 | ||
Biodegradation of poly(epsilon-caprolactone)/starch blends and composites in composting and culture environments: the effect of compatibilization on the inherent biodegradability of the host polymer. | The biodegradability of poly(epsilon-caprolactone) (PCL) was studied in blends and composites of modified and granular starch. Four types of PCL-starch compositions were prepared: (i) PCL-granular starch blends; (ii) hydrophobic coating of starch particles by n-butylisocyanate (C(4) starch) and octadecyltrichlorosilane... | 10.1016/s0008-6215(03)00236-2 | 12,892,943 | D001672:Biocompatible Materials; D001673:Biodegradation, Environmental; D002208:Caproates; D003470:Culture Media; D005658:Fungi; D057927:Hydrophobic and Hydrophilic Interactions; D007783:Lactones; D008855:Microscopy, Electron, Scanning; D010316:Particle Size; D011108:Polymers; D012988:Soil Microbiology; D013213:Starch;... | Carbohydrate research | 2,003 | D001672:Biocompatible Materials; D002208:Caproates; D003470:Culture Media; D007783:Lactones; D011108:Polymers; C121056:caprolactone; D013213:Starch |
Successful selection of an infection-protective anti-Staphylococcus aureus monoclonal antibody and its protective activity in murine infection models. | Recent clinical trials to develop anti-methicillin-resistant Staphylococcus aureus (MRSA) therapeutic antibodies have met unsuccessful sequels. To develop more effective antibodies against MRSA infection, a panel of mAbs against S. aureus cell wall was generated and then screened for the most protective mAb in mouse in... | 10.1111/1348-0421.12242 | 25,659,598 | D000818:Animals; D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D005260:Female; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus; D051379:Mice; D008807:Mice, Inbred BALB C; D018805:Sepsis; D013203:Staphylococcal Inf... | Microbiology and immunology | 2,015 | D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal |
Cytogenetic analysis in the spermatogenesis of Triatoma melanosoma (Reduviidae; Heteroptera). | Triatomines are of great concern in public health because they are vectors of Chagas' disease. This study presents an analysis of the species Triatoma melanosoma. The cytogenetic characteristics of triatomines include holocentric chromosomes, post-reductional meiosis in the sex chromosomes and nucleolar fragmentation i... | 10.4238/vol7-2gmr411 | 18,551,398 | D000818:Animals; D002875:Chromosomes; D020732:Cytogenetic Analysis; D008297:Male; D008540:Meiosis; D010078:Oxazines; D012730:Sex Chromosomes; D013091:Spermatogenesis; D013737:Testis; D014224:Triatoma | Genetics and molecular research : GMR | 2,008 | D010078:Oxazines; C002313:PAcein |
Plant disease management in organic farming systems. | Organic farming (OF) has significantly increased in importance in recent decades. Disease management in OF is largely based on the maintenance of biological diversity and soil health by balanced crop rotations, including nitrogen-fixing and cover crops, intercrops, additions of manure and compost and reductions in soil... | 10.1002/ps.4145 | 26,331,771 | D018556:Crops, Agricultural; D058871:Organic Agriculture; D010572:Pest Control, Biological; D010935:Plant Diseases; D058728:Weed Control | Pest management science | 2,016 | |
[Do we defend a brain oriented view of death?]. | AIMS
To propose a new formulation of death based on the mechanisms involved in consciousness generation in human beings.
DEVELOPMENT
Any complete formulation of death must include three different elements: a definition of death, its anatomofunctional substratum and the tests required to diagnose death. The three brai... | 12,235,573 | D001143:Arousal; D001364:Awareness; D001926:Brain Death; D001933:Brain Stem; D002540:Cerebral Cortex; D003243:Consciousness; D004027:Diencephalon; D006801:Humans | Revista de neurologia | 2,002 | ||
Isolation of compound microsatellite markers for the endangered plant Neolitsea sericea (Lauraceae). | UNLABELLED
PREMISE OF THE STUDY
The development of compound microsatellite markers was conducted in Neolitsea sericea to investigate genetic diversity and population genetic structure of this endangered insular species. •
METHODS AND RESULTS
Using the compound microsatellite marker technique, 10 compound microsate... | 10.3732/ajb.1000348 | 21,616,833 | American journal of botany | 2,010 | ||
Impaired fibrinolysis in retinal vein occlusion: a role for genetic determinants of PAI-1 levels. | Few and contrasting data are available on the presence of a thrombophilic state in patients with retinal vein occlusion (RVO), and we have previously demonstrated a role of elevated PAI-1 activity as a risk factor for this condition. The present study was undertaken to investigate whether PAI 4G/5G and ACE I/D polymorp... | 10.1160/TH03-08-0509 | 15,213,845 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D005342:Fibrinolysis; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D007703:Peptidyl-Dipeptidase A; D017395:Plasminogen Activator Inhibitor 1; D011110:Polymorphism, Genetic; D... | Thrombosis and haemostasis | 2,004 | D017395:Plasminogen Activator Inhibitor 1; D007703:Peptidyl-Dipeptidase A |
Identification of the protein encoded by the human diffuse B-cell lymphoma (dbl) oncogene. | The dbl oncogene was initially isolated from a human diffuse B-cell lymphoma. Antisera from mice bearing tumors induced by this oncogene specifically detected a protein of about 66 kDa (p66) in dbl transformants. dbl cDNA-selected poly(A)+ RNA isolated from a transfectant clone expressing p66 directed the in vitro synt... | 10.1073/pnas.83.23.8868 | 3,491,366 | D001402:B-Lymphocytes; D003593:Cytoplasm; D004273:DNA, Neoplasm; D006801:Humans; D008223:Lymphoma; D008566:Membranes; D008970:Molecular Weight; D009363:Neoplasm Proteins; D009857:Oncogenes; D010750:Phosphoproteins; D010768:Phosphoserine | Proceedings of the National Academy of Sciences of the United States of America | 1,986 | D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D010750:Phosphoproteins; D010768:Phosphoserine |
Accounting for population structure in genomic predictions of Eucalyptus globulus. | Genetic groups have been widely adopted in tree breeding to account for provenance effects within pedigree-derived relationship matrices. However, provenances or genetic groups have not yet been incorporated into single-step genomic BLUP ("HBLUP") analyses of tree populations. To quantify the impact of accounting for p... | 10.1093/g3journal/jkac180 | 35,920,792 | D005052:Eucalyptus; D016678:Genome; D023281:Genomics; D005838:Genotype; D006801:Humans; D008957:Models, Genetic; D010641:Phenotype; D000069600:Plant Breeding | G3 (Bethesda, Md.) | 2,022 | |
[Foreign patients in psychosomatic ambulatory care]. | To investigate differences between the complaints of foreign and of German patients who presented at our psychosomatic outpatient department, we documented relevant social data and the results of all diagnostic interviews conducted in 1990. Of the 608 patients (100%), 542 (89.1%) were German and 66 (10.9%) of other nat... | 8,456,149 | D000328:Adult; D000553:Ambulatory Care; D003131:Combined Modality Therapy; D003431:Cross-Cultural Comparison; D005260:Female; D005783:Gender Identity; D005858:Germany; D006801:Humans; D008297:Male; D008875:Middle Aged; D011575:Psychoanalytic Therapy; D011602:Psychophysiologic Disorders; D012917:Social Adjustment; D0129... | Psychotherapie, Psychosomatik, medizinische Psychologie | 1,993 | ||
Antibacterial activity of a new tetracyclic quinolone, No. 5290, against norfloxacin- and ciprofloxacin-resistant strains of Staphylococcus aureus. | The antibacterial activity of a new tetracyclic quinolone, No. 5290, against 25 strains of Staphylococcus aureus clinically isolated in Japan in 1988-1989 was determined. The minimum inhibitory concentrations (MICs) of No. 5290 against both quinolone-susceptible (MIC: norfloxacin less than or equal to 6.25 micrograms/m... | 10.1248/cpb.39.2644 | 1,666,861 | D000890:Anti-Infective Agents; D002851:Chromatography, High Pressure Liquid; D002939:Ciprofloxacin; D004352:Drug Resistance, Microbial; D024841:Fluoroquinolones; D009154:Mutation; D009643:Norfloxacin; D010879:Piperazines; D015363:Quinolones; D013211:Staphylococcus aureus; D013844:Thiazoles | Chemical & pharmaceutical bulletin | 1,991 | D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D010879:Piperazines; D015363:Quinolones; D013844:Thiazoles; C074008:tetracyclic quinolone No. 5290; D002939:Ciprofloxacin; D009643:Norfloxacin |
Infrared spectra of CO2-doped 4He clusters, 4HeN-CO2, with N=1-60. | High resolution spectra of (4)He(N)-CO(2) clusters are studied in the region of the CO(2) nu(3) fundamental band (approximately 2300 cm(-1)). The clusters are produced in a pulsed supersonic jet expansion from a cooled nozzle source and probed by direct absorption using a tunable diode laser operating in a rapid-scan m... | 10.1063/1.2822903 | 18,247,950 | The Journal of chemical physics | 2,008 | ||
Effects of Focal Vibration over Upper Limb Muscles on the Activation of Sensorimotor Cortex Network: An EEG Study. | Studying the therapeutic effects of focal vibration (FV) in neurorehabilitation is the focus of current research. However, it is still not fully understood how FV on upper limb muscles affects the sensorimotor cortex in healthy subjects. To explore this problem, this experiment was designed and conducted, in which FV w... | 10.1155/2019/9167028 | 31,263,527 | D000328:Adult; D001132:Arm; D004569:Electroencephalography; D006801:Humans; D008297:Male; D009068:Movement; D018482:Muscle, Skeletal; D000066530:Neurological Rehabilitation; D066191:Sensorimotor Cortex; D012815:Signal Processing, Computer-Assisted; D020521:Stroke; D034941:Upper Extremity; D014732:Vibration | Journal of healthcare engineering | 2,019 | |
A Pilot One Group Feasibility, Acceptability, and Initial Efficacy Trial of LISTEN for Loneliness in Lonely Stroke Survivors. | Loneliness is a prevalent problem for adult stroke survivors, and a known contributor to hypertension, secondary stroke, functional decline, poorer quality of life, and mortality in older adults. LISTEN (Loneliness Intervention using Story Theory to Enhance Nursing-sensitive outcomes), a theoretically based behavioral ... | 10.1177/23779608211015154 | 34,017,913 | SAGE open nursing | 2,021 | ||
Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha. | We earlier reported a genome-wide significant linkage to schizophrenia at chromosome 17 that was identified in a single pedigree (C702) consisting of six affected, male siblings with DSM-IV schizophrenia and prominent mood symptoms. In this study, we adopted several approaches in an attempt to map the putative disease ... | 10.1038/mp.2009.96 | 19,786,960 | D000293:Adolescent; D000328:Adult; D000483:Alleles; D002031:Bulgaria; D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D005260:Female; D020022:Genetic Predisposition to Disease; D005838:Genotype; D005858:Germany; D006239:Haplotypes; D006801:Humans; D007494:Ireland; D008297:Male; D018895:Microsatellite R... | Molecular psychiatry | 2,010 | C496628:PRKCA protein, human; D051571:Protein Kinase C-alpha |
Postgraduate perspectives on mentoring undergraduate researchers for talent development. | Undergraduate research experiences are critical for the talent development of the STEM research workforce, and research mentors play an influential role in this process. Given the many life science majors seeking research experiences at universities, graduate and postdoctoral researchers (i.e., postgraduates) provide m... | 10.1111/nyas.14966 | 36,717,767 | D006801:Humans; D000071252:Mentoring; D008611:Mentors; D013334:Students; D012108:Research Personnel; D014495:Universities | Annals of the New York Academy of Sciences | 2,023 | |
Biochemical Defense Responses in Red Rice Genotypes Possessing Differential Resistance to Brown Planthopper, Nilaparvata lugens (Stål). | The brown planthopper [Nilaparvata lugens (Stål.)] is one of the most destructive insect pests in all the rice-growing regions of the world. The pest is complicated to manage through the blanket application of chemical pesticides. The development of stable, durable N. lugens-resistant rice varieties is the most economi... | 10.3390/insects14070632 | 37,504,637 | Insects | 2,023 | ||
Hypoparathyroidism. | Hypoparathyroidism is a rare endocrine disease caused by an absence or insufficient production of parathormone. Parathormone deficiency leads to lower serum calcium concentration that is responsible for patients' neuromuscular symptoms. Conventional treatment consists of calcium and active vitamin D metabolites adminis... | 37,734,939 | D006801:Humans; D002118:Calcium; D007011:Hypoparathyroidism; D010281:Parathyroid Hormone; D035583:Rare Diseases | Casopis lekaru ceskych | 2,023 | D002118:Calcium; D010281:Parathyroid Hormone | |
Faith: a concept analysis. | AIM
This paper reports a concept analysis of faith.
BACKGROUND
There are numerous scholars who consider spirituality and religiosity as they relate to health and nursing. Faith is often implied as linked to these concepts but deserves distinct exploration. In addition, as nursing practice conducted within communities... | 10.1111/j.1365-2648.2011.05734.x | 21,679,222 | D000328:Adult; D003152:Community Health Nursing; D003210:Concept Formation; D005260:Female; D006694:Holistic Health; D006801:Humans; D008297:Male; D033262:Narration; D009723:Nurse-Patient Relations; D009742:Nursing Theory; D036301:Qualitative Research; D012068:Religion and Medicine; D029181:Spirituality | Journal of advanced nursing | 2,011 | |
siRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells. | Recent human studies found that the mRNA expression level of aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2) was positively associated with the prognosis of breast cancer. In this study, we used small interfering RNA techniques to knockdown ARNT2 expression in MCF7 human breast cancer cells, and found that an ... | 10.1016/j.febslet.2011.09.017 | 21,945,317 | D051784:Aryl Hydrocarbon Receptor Nuclear Translocator; D051792:Basic Helix-Loop-Helix Transcription Factors; D001943:Breast Neoplasms; D045744:Cell Line, Tumor; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D055785:Gene Knockdown Techniques; D006801:Humans; D051793:Hypoxia-Inducible Factor 1; D009363... | FEBS letters | 2,011 | C490989:ARNT2 protein, human; D051792:Basic Helix-Loop-Helix Transcription Factors; D051793:Hypoxia-Inducible Factor 1; D009363:Neoplasm Proteins; D034741:RNA, Small Interfering; D051784:Aryl Hydrocarbon Receptor Nuclear Translocator |
Isolation, purification and assessment of viability of spermatogenic cells from testicular biopsies of azoospermic men. | The success of spermatid microinjection has generated many concerns. In particular, there is a lack of appropriate methodology for the isolation of large homogeneous populations of spermatids, with minimum loss of viability, from the testicular tissue of azoospermic men. Here we have compared two different isolation me... | 10.1093/humrep/13.3.639 | 9,572,426 | D002469:Cell Separation; D002470:Cell Survival; D003850:Deoxyribonuclease I; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D009845:Oligospermia; D013087:Spermatids; D013094:Spermatozoa; D013737:Testis; D014357:Trypsin | Human reproduction (Oxford, England) | 1,998 | D003850:Deoxyribonuclease I; D014357:Trypsin |
Recent advances in the development of novel mucosal adjuvants and antigen delivery systems. | Mucosal infections and associated diseases remain a major socio-economic burden to society. Since parenteral immunizations fail to induce efficient protective immunity at mucosal surfaces, mucosal immunization is a logical approach to prevent and treat mucosally-initiated infections. All currently approved human mucosa... | 20,861,683 | Human vaccines | 2,010 | |||
Human ACE-2, MCP1 and micro-RNA 146 as Novel Markers for COVID- 19 Affection and Severity. | BACKGROUND & AIMS
Coronavirus disease - 2019 (COVID-19) is a major pandemic that causes high morbidity and mortality rates.
AIM OF THIS STUDY
to detect the relations between many risk factors, ACE-2, MCP-1, Micro RNA 146 gene expression, and COVID-19 infection and disease severity.
METHODS
This study was carried ou... | 10.2174/1871526522666220829153042 | 36,043,754 | D006801:Humans; D000086382:COVID-19; D000086402:SARS-CoV-2; D000085962:Angiotensin-Converting Enzyme 2; D007703:Peptidyl-Dipeptidase A; D012313:RNA; D035683:MicroRNAs | Infectious disorders drug targets | 2,023 | D000085962:Angiotensin-Converting Enzyme 2; D007703:Peptidyl-Dipeptidase A; D012313:RNA; C542542:MIRN146 microRNA, human; D035683:MicroRNAs |
An Institutional Guide for Formulary Decisions of Biosimilars. | Biologics have changed the landscape for the management of many debilitating chronic diseases but account for a significant expenditure of medications globally. Fortunately, advances in technology paved the way for the introduction of biosimilars, which are highly similar to the originator biologics. In the quest to re... | 10.1177/00185787221138007 | 36,644,755 | Hospital pharmacy | 2,023 | ||
Endoscopic haemostasis by polypectomy: a case of sigmoid colon tubular adenoma with arterial haemorrhage. | An 84-year-old woman was admitted to our hospital with a massive lower intestinal bleeding (LIB). The enhanced CT showed extravasation of blood in the sigmoid colon during the arterial phase. After discussion with the interventional radiologists, we proceeded to perform emergency colonoscopy that demonstrated massive g... | 24,599,425 | D000236:Adenoma; D000369:Aged, 80 and over; D003111:Colonic Polyps; D020685:Colonoscopes; D005260:Female; D006471:Gastrointestinal Hemorrhage; D016558:Hemostasis, Endoscopic; D006801:Humans; D012811:Sigmoid Neoplasms | BMJ case reports | 2,014 | ||
Unresolving hip tendonitis leads to discovery of malignant tumor. | OBJECTIVE
To discuss a case of malignant bone tumor in the left hip of a patient who sought treatment following a tennis injury.
CLINICAL FEATURES
A 27-year-old male patient visited a chiropractic clinic 6 months after a twisting injury to his left hip which occurred while playing tennis. His pain had remained modera... | 10.1016/S0161-4754(03)00013-7 | 12,704,314 | D000328:Adult; D019644:Arthroplasty, Replacement, Hip; D002062:Bursitis; D002813:Chondrosarcoma; D005266:Femoral Neoplasms; D005270:Femur Head; D025981:Hip Injuries; D006801:Humans; D008297:Male; D011859:Radiography; D052256:Tendinopathy; D013715:Tennis; D013997:Time Factors; D016896:Treatment Outcome | Journal of manipulative and physiological therapeutics | 2,003 | |
A Commentary on the Effect of Targeted Temperature Management in Patients Resuscitated from Cardiac Arrest. | The members of the International Liaison Committee on Resuscitation (ILCOR) Advanced Life Support Task Force have written a comprehensive summary of trials of the effectiveness of induced hypothermia (IH) or targeted temperature management (TTM) in comatose patients after cardiac arrest (CA). However, in-depth analysis... | 10.1089/ther.2022.0041 | 36,378,270 | D006801:Humans; D016887:Cardiopulmonary Resuscitation; D003128:Coma; D006323:Heart Arrest; D007036:Hypothermia, Induced; D058687:Out-of-Hospital Cardiac Arrest; D013696:Temperature | Therapeutic hypothermia and temperature management | 2,023 | |
Web-based diabetes control. | We developed a diabetes management system with a Web interface that allowed patients to transmit their physiological data using either a PC Web browser or a mobile phone capable of working with the WAP protocol. The system could generate automatic responses to input values in accordance with a set of ranges previously ... | 10.1258/1357633042026288 | 15,494,085 | D000328:Adult; D000368:Aged; D001292:Attitude to Computers; D003920:Diabetes Mellitus; D006801:Humans; D020407:Internet; D008875:Middle Aged; D017060:Patient Satisfaction; D019114:Remote Consultation; D013030:Spain | Journal of telemedicine and telecare | 2,004 | |
Rehydration with glycerol: endocrine, cardiovascular, and thermoregulatory responses during exercise in the heat. | The impact of rehydration with glycerol on cardiovascular and thermoregulatory responses during exercise in the heat was studied in eight highly trained male cyclists. Each subject completed three dehydration-rehydration experimental trials that differed only in the rehydration treatment, each separated by 7 days. Befo... | 10.1152/japplphysiol.00187.2005 | 16,210,441 | D000328:Adult; D001833:Body Temperature Regulation; D002320:Cardiovascular Physiological Phenomena; D003681:Dehydration; D004326:Drinking; D004703:Endocrine System; D015444:Exercise; D005080:Exercise Test; D005440:Fluid Therapy; D005990:Glycerol; D006728:Hormones; D006358:Hot Temperature; D006801:Humans; D008297:Male; ... | Journal of applied physiology (Bethesda, Md. : 1985) | 2,006 | D006728:Hormones; D015532:Rehydration Solutions; D005990:Glycerol |
Chiral superstructure of aragonite similar to Turritella terebra shell induced by CTAB's adsorption chirality. | A twisted dumbbell-like chiral superstructure can be easily assembled in aragonite under the co-action of CTAB and Mg2+, producing a microstructure that is very similar to that of Turritella terebra shell. Asymmetric adsorption of the CTAB head group on aragonite, namely "adsorption chirality", is the reason for the ch... | 10.1039/d2cc06615g | 36,786,057 | Chemical communications (Cambridge, England) | 2,023 | ||
Endovascular Treatment of No-Stent Zones… Quo Vadis? | Endovascular treatment of peripheral artery disease has recently become more important due to its minimally invasive nature. Elderly patients as well as fragile patients, like diabetics and those with end-stage renal disease, can benefit from this low-morbidity/-mortality treatment. Very successful results have been ac... | 31,476,793 | D000368:Aged; D000800:Angioplasty, Balloon; D001157:Arterial Occlusive Diseases; D005263:Femoral Artery; D006801:Humans; D058729:Peripheral Arterial Disease; D011150:Popliteal Artery; D015607:Stents; D016896:Treatment Outcome | Surgical technology international | 2,019 | ||
Efficiency of intraoperative endoscopic inspection in reducing residuals in canal-wall-up surgery for pediatric cholesteatoma involving the mastoid. | OBJECTIVE
To investigate the efficiency of additional intraoperative endoscopic inspection in reducing residual cholesteatoma in pediatric cholesteatoma involving the mastoid treated with classic canal-wall-up mastoidectomy and tympanoplasty.
MATERIALS AND METHODS
32 cases of pediatric cholesteatoma involving the mas... | 10.1007/s00405-023-07857-6 | 36,700,981 | D006801:Humans; D002648:Child; D008416:Mastoid; D018424:Cholesteatoma, Middle Ear; D004432:Ear, Middle; D004724:Endoscopy; D014433:Tympanoplasty; D016896:Treatment Outcome; D012189:Retrospective Studies | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery | 2,023 | |
Cytotoxicity mediated by the Fas ligand (FasL)-activated apoptotic pathway in stem cells. | Whereas it is now clear that human bone marrow stromal cells (BMSCs) can be immunosuppressive and escape cytotoxic lymphocytes (CTLs) in vitro and in vivo, the mechanisms of this phenomenon remain controversial. Here, we test the hypothesis that BMSCs suppress immune responses by Fas-mediated apoptosis of activated lym... | 10.1074/jbc.M109.032235 | 19,531,476 | D017209:Apoptosis; D053181:Caspase 8; D002478:Cells, Cultured; D018920:Coculture Techniques; D053222:Fas Ligand Protein; D006801:Humans; D007166:Immunosuppressive Agents; D019169:Jurkat Cells; D008214:Lymphocytes; D008954:Models, Biological; D012313:RNA; D034741:RNA, Small Interfering; D013234:Stem Cells; D013997:Time ... | The Journal of biological chemistry | 2,009 | D053222:Fas Ligand Protein; D007166:Immunosuppressive Agents; D034741:RNA, Small Interfering; D012313:RNA; D053181:Caspase 8 |
The characteristics of screening and confirmatory test results for HIV in Xi'an, China. | OBJECTIVES
Individuals with recent or acute HIV infection are more infectious than those with established infection. Our objective was to analyze the characteristics of detection among HIV infections in Xi'an.
METHODS
A 4th-generation kit (Architect HIV Ag/Ab Combo) and three 3rd-generationEIA kits (WanTai, XinChuang... | 10.1371/journal.pone.0180071 | 28,686,629 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002681:China; D003955:Diagnostic Tests, Routine; D042241:Early Diagnosis; D005260:Female; D015483:HIV Antibodies; D015488:HIV Antigens; D015658:HIV Infections; D015497:HIV-1; D015498:HIV-2; D006801:Humans; D008297:Male; D008403:... | PloS one | 2,017 | D015483:HIV Antibodies; D015488:HIV Antigens; D014764:Viral Proteins |
Raising suspicions with the Food and Drug Administration: detecting misconduct. | The clinical Bioresearch Monitoring (BIMO) oversight program of the US Food and Drug Administration (FDA) assesses the quality and integrity of data submitted to the FDA for new product approvals and human subjects protection during clinical studies. A comprehensive program of on-site inspections and data verification,... | 10.1007/s11948-010-9232-4 | 20,842,536 | D002986:Clinical Trials as Topic; D032984:Ethics, Research; D006805:Human Experimentation; D006801:Humans; D040541:Marketing; D012107:Research Design; D015871:Scientific Misconduct; D014481:United States; D014486:United States Food and Drug Administration | Science and engineering ethics | 2,010 | |
The prevalence and predictors of androgen deficiency in Taiwanese men with type 2 diabetes. | OBJECTIVE
To evaluate the prevalence and predictors of androgen deficiency (AD) in Taiwanese men with type 2 diabetes mellitus (T2DM).
METHODS
A recent hospital-based series of Western populations showed that 30%-50% of men with T2DM have low testosterone, and AD links to DM and obesity bidirectionally. However, data... | 23,676,359 | D000367:Age Factors; D000368:Aged; D015992:Body Mass Index; D002097:C-Reactive Protein; D002784:Cholesterol; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2; D006801:Humans; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome; D00887... | Urology | 2,013 | D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D014280:Triglycerides; D014527:Uric Acid; D013739:Testosterone; D002097:C-Reactive Protein; D002784:Cholesterol | |
Economic aspects of the control of Aujeszky's disease in the European Community. | Aujeszky's disease (AD) is as much an economic problem as an epidemiological one. Several strategies are available for controlling the disease, and it is the task of the economist to compare all control options; the "best" strategy may differ depending on whether it is defined at the farm, regional, national or Europea... | 7,810,438 | D000818:Animals; D005062:European Union; D011557:Pseudorabies; D013552:Swine; D013553:Swine Diseases | Acta veterinaria Hungarica | 1,994 | ||
The temporal dynamics of cognitive reactivity and their association with the depression risk: an exploratory study. | BACKGROUND
Cognitive reactivity is the change in depressive thinking in response to negative mood. Previous research indicates that cognitive reactivity is an important variable in the etiology and course of depression. The present study tested which time interval after a negative mood induction is critical for the pre... | 10.1159/000368782 | 25,720,814 | D000328:Adult; D000339:Affect; D000368:Aged; D003071:Cognition; D003863:Depression; D003866:Depressive Disorder; D003865:Depressive Disorder, Major; D004644:Emotions; D005260:Female; D005500:Follow-Up Studies; D005858:Germany; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008875:Middle Aged; D011237:... | Psychopathology | 2,015 | |
Completion of nonreducible Le Fort fractures by Le Fort I osteotomy: sometimes an inevitable choice to avoid postoperative malocclusion. | The aim of this study was to prospectively evaluate the use of a simultaneous Le Fort I osteotomy for completion of nonreducible Le Fort fractures. We analyzed the clinical and radiological data of 44 patients with Le Fort fractures, 9 of whom presented with a nonreducible type. Seven patients with an incomplete Le For... | 10.1097/SCS.0000000000001178 | 25,569,419 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D005593:Fracture Fixation, Internal; D017102:Fracture Healing; D006801:Humans; D019248:Jaw Fixation Techniques; D008297:Male; D008310:Malocclusion; D008337:Mandibular Fractures; D008440:Maxillary Fractures; D008875:Middle... | The Journal of craniofacial surgery | 2,015 | |
Assessment of COL1A1 and MMP9 expression in patients with dermatochalasis. | PURPOSE
Dermatochalasis is a clinical condition characterized by loss of elasticity of eyelid skin and soft tissue, which typically affects the elderly population. The aim of this study is to investigate the mRNA expression levels of collagen type 1 alpha 1 (COL1A1) and matrix metalloproteinase-9 (MMP9) genes in dermat... | 10.1007/s10792-020-01373-w | 32,323,045 | D000328:Adult; D000368:Aged; D019882:Blepharoplasty; D001763:Blepharoptosis; D024042:Collagen Type I; D000090602:Collagen Type I, alpha 1 Chain; D005143:Eyelids; D006801:Humans; D020780:Matrix Metalloproteinase 9; D011446:Prospective Studies | International ophthalmology | 2,020 | D024042:Collagen Type I; D000090602:Collagen Type I, alpha 1 Chain; C579270:MMP9 protein, human; D020780:Matrix Metalloproteinase 9 |
Chromatographic characterization on flavonoids and triterpenes of leaves and flowers of 15 crataegus L. species. | The Hawthorn (Crataegus L.) is the most commonly used herb for treating cardiovascular diseases. The purpose of this paper was the analysis and comparison of HPTLC chromatographic profiles of flavonoids and triterpenes of leaves and flowers of 15 Crataegus L. species occurring throughout Eurasia and North America, and ... | 10.1080/14786419.2018.1528589 | 30,417,671 | D002845:Chromatography; D027825:Crataegus; D005419:Flavonoids; D035264:Flowers; D010936:Plant Extracts; D018515:Plant Leaves; D013045:Species Specificity; D014315:Triterpenes | Natural product research | 2,020 | D005419:Flavonoids; D010936:Plant Extracts; D014315:Triterpenes; C007145:crataegus extract |
Telehealth in palliative care during the COVID-19 pandemic: A systematic mixed studies review. | BACKGROUND
The coronavirus disease-2019 (COVID-19) pandemic caused unprecedented disruption to healthcare delivery worldwide. The use of telehealth practices rapidly expanded during the pandemic, while its application in palliative care remains a conflicted issue.
AIMS
The aims of this study were to evaluate users' r... | 10.1111/wvn.12637 | 36,942,832 | Worldviews on evidence-based nursing | 2,023 | ||
Preparental hormone levels and parenting experience in male cotton-top tamarins, Saguinus oedipus. | Male cotton-top tamarins, Saguinus oedipus, display hormonal changes associated with parenting prior to the birth of their infants. Here we examined the hormonal changes that occurred in experienced and inexperienced fathers during the postconception period, prior to the birth of infants. Noninvasive techniques were us... | 10.1006/hbeh.2000.1617 | 11,038,290 | D000818:Animals; D000831:Animals, Newborn; D013196:Dihydrotestosterone; D006728:Hormones; D006854:Hydrocortisone; D008297:Male; D010332:Paternal Behavior; D012452:Saguinus; D013739:Testosterone | Hormones and behavior | 2,000 | D006728:Hormones; D013196:Dihydrotestosterone; D013739:Testosterone; D006854:Hydrocortisone |
Beam configurations for 3D tomographic intensity modulated radiation therapy. | We extend the theory of three-dimensional (3D) tomographic intensity modulated radiation therapy (IMRT). The geometry consists of two-dimensional modulated beams on a sphere centred in the tumour. The theory provides an efficient algorithm for computing beam modulation patterns that approximately 'reconstruct' the pres... | 10.1088/0031-9155/47/5/306 | 11,931,470 | D000465:Algorithms; D005583:Fourier Analysis; D006801:Humans; D015233:Models, Statistical; D017785:Photons; D020266:Radiotherapy, Conformal; D014965:X-Rays | Physics in medicine and biology | 2,002 | |
The skin-dwelling microfilariae of Monanema martini in Lemniscomys striatus as potential drug screening model for onchocerciasis: midazolam effect in vitro. | The murid model of Monanema martini in Lemniscomys striatus was used to evaluate its potential as drug screening model in onchocerciasis. It had been described that the histopathology and the reaction to diethylcarbamazine treatment of this model closely resemble human onchocerciasis. To study further similarities the ... | 2,907,264 | D000818:Animals; D002465:Cell Movement; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D004431:Ear, External; D005370:Filarioidea; D008842:Microfilariae; D008874:Midazolam; D009115:Muridae; D009855:Onchocerciasis; D012867:Skin | Acta tropica | 1,988 | D008874:Midazolam | |
Effect of enriched environment and predictable chronic stress on spatial memory in adolescent rats: Predominant expression of BDNF, nNOS, and interestingly malondialdehyde in the right hippocampus. | Little is known about the mechanisms that promote divergence of function between left and right in the hippocampus, which is most affected by external factors and critical for spatial memory. We investigated the levels of memory-related mediators in the left and right hippocampus and spatial memory in rats exposed to p... | 10.1016/j.brainres.2019.146326 | 31,299,186 | D000367:Age Factors; D000818:Animals; D001921:Brain; D019208:Brain-Derived Neurotrophic Factor; D003345:Corticosterone; D004777:Environment; D006624:Hippocampus; D008297:Male; D008315:Malondialdehyde; D018782:Maze Learning; D009473:Neuronal Plasticity; D052248:Nitric Oxide Synthase Type I; D051381:Rats; D017207:Rats, S... | Brain research | 2,019 | D019208:Brain-Derived Neurotrophic Factor; D008315:Malondialdehyde; D052248:Nitric Oxide Synthase Type I; C496321:Nos1 protein, mouse; D003345:Corticosterone |
Changes of plasma lipids during weight reduction in females depends on APOA5 variants. | BACKGROUND
Apolipoprotein A5 (APOA5) is a determinant of plasma lipids, and its role in body mass index (BMI) determination is discussed. This study was aimed at the investigation of the relationship between common APOA5 gene variants and body weight/plasma lipid decrease in overweight females.
METHODS
We analyzed 98... | 10.1159/000165358 | 18,946,207 | D000328:Adult; D000704:Analysis of Variance; D000072040:Apolipoprotein A-V; D001054:Apolipoproteins A; D015992:Body Mass Index; D008078:Cholesterol, LDL; D015331:Cohort Studies; D018153:Czech Republic; D005260:Female; D005787:Gene Frequency; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D050356:Lipid Met... | Annals of nutrition & metabolism | 2,008 | C437704:APOA5 protein, human; D000072040:Apolipoprotein A-V; D001054:Apolipoproteins A; D008078:Cholesterol, LDL; D014280:Triglycerides |
Making modern scienceHow the Victorians Took Us to the Moon Iwan Rhys Morus Pegasus, 2022. 400 pp. | Victorian values permeate contemporary scientific culture, maintains a historian. | 10.1126/science.adf4691 | 36,656,938 | Science (New York, N.Y.) | 2,023 | ||
Oxidation of Disulfides to Thiolsulfinates with Hydrogen Peroxide and a Cyclic Seleninate Ester Catalyst. | Cyclic seleninate esters function as mimetics of the antioxidant selenoenzyme glutathione peroxidase. They catalyze the reduction of harmful peroxides with thiols, which are converted to disulfides in the process. The possibility that the seleninate esters could also catalyze the further oxidation of disulfides to thio... | 10.3390/molecules200610748 | 26,111,166 | D000975:Antioxidants; D003553:Cystine; D004220:Disulfides; D004952:Esters; D005979:Glutathione Peroxidase; D006861:Hydrogen Peroxide; D018716:Molecular Mimicry; D016566:Organoselenium Compounds; D010084:Oxidation-Reduction; D013438:Sulfhydryl Compounds | Molecules (Basel, Switzerland) | 2,015 | D000975:Antioxidants; D004220:Disulfides; D004952:Esters; C500350:N,N'-dibenzoylcystine; D016566:Organoselenium Compounds; D013438:Sulfhydryl Compounds; D003553:Cystine; D006861:Hydrogen Peroxide; D005979:Glutathione Peroxidase |
Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity. | The production of 14CO2 in the breath from an intravenous dose of [14C-N-methyl]-erythromycin (the erythromycin breath test [ERMBT]) and the measurement of the ratio of 6-beta-cortisol to free cortisol (6-beta-F/FF) in the urine have each been proposed as means of measuring hepatic P450IIIA catalytic activity in patien... | 10.1038/clpt.1992.140 | 1,526,083 | D001189:Aryl Hydrocarbon Hydroxylases; D001944:Breath Tests; D002245:Carbon Dioxide; D016572:Cyclosporine; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System; D006801:Humans; D006854:Hydrocortisone; D008099:Liver; D010089:Oxidoreductases, N-Demethylating; D011565:Psoriasis; D012044:Regression Analys... | Clinical pharmacology and therapeutics | 1,992 | D002245:Carbon Dioxide; D016572:Cyclosporine; D003577:Cytochrome P-450 Enzyme System; D014217:Troleandomycin; D001189:Aryl Hydrocarbon Hydroxylases; D051544:Cytochrome P-450 CYP3A; D010089:Oxidoreductases, N-Demethylating; D012293:Rifampin; D006854:Hydrocortisone |
Effects of the slow calcium-channel blocker verapamil on phosphatic metabolism of crystalline lens. | The effects of calcium-channel blockade on phosphate metabolism in the rabbit lens ex vivo was studied using phosphorus-31 nuclear magnetic resonance (NMR) spectroscopy. Rates-of-change of the intralenticular pH and the following phosphatic metabolites in the lens were determined: ATP, ADP, inorganic orthophosphate, su... | 10.1016/s0014-4835(88)80072-1 | 3,350,061 | D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005997:Glycerylphosphorylcholine; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007908:Lens, Crystalline; D009702:Nucleoside Diphosphate Sugars; D010710:Phosphates; D011817:Rabb... | Experimental eye research | 1,988 | D009702:Nucleoside Diphosphate Sugars; D010710:Phosphates; D013403:Sugar Phosphates; D005997:Glycerylphosphorylcholine; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D014700:Verapamil |
Pediatric cerebral angiography: analysis of utilization and findings. | Pediatric neuroendovascular procedures are being performed with increasing frequency, for various indications. Reported here is the experience of interventionally trained neurologists performing pediatric cerebral diagnostic angiography between August 1, 2005, and April 30, 2008, at a single tertiary institution. Data ... | 10.1016/j.pediatrneurol.2008.10.006 | 19,135,622 | D000293:Adolescent; D001921:Brain; D020785:Central Nervous System Vascular Malformations; D002533:Cerebral Angiography; D002648:Child; D002675:Child, Preschool; D003710:Demography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D002538:Intracranial Arteriovenous Malformations; D008297:Male | Pediatric neurology | 2,009 | |
An efficient method for culturing human breast epithelium: analysis of results. | We have examined the possibility of obtaining primary cultures from breast tissue utilizing a method especially developed for breast epithelium. The number of specimens able to grow in culture was very high: 82.8%, 64.3%, 75.0% and 77.8%, respectively, for primary breast cancer, skin recurrences, inflammatory breast ca... | 10.1177/030089169107700602 | 1,803,709 | D001943:Breast Neoplasms; D046508:Culture Techniques; D004848:Epithelium; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local | Tumori | 1,991 | |
Endocrinologic and metabolic factors in atypical presentations of slipped capital femoral epiphysis. Report of four cases and review of the literature. | Although the usual etiology of slipped capital femoral epiphysis (SCFE) is idiopathic, there are many underlying endocrinologic, biomechanical, metabolic, and connective tissue abnormalities that increase the predisposition to slippage. Four case reports and a review of the literature demonstrate tht hypopituitarism, r... | 6,354,545 | D000328:Adult; D001859:Bone Neoplasms; D002648:Child; D004839:Epiphyses, Slipped; D005260:Female; D005270:Femur Head; D006801:Humans; D007512:Ischium; D007592:Joint Diseases; D007676:Kidney Failure, Chronic; D008297:Male; D011859:Radiography; D011878:Radiotherapy; D012208:Rhabdomyosarcoma; D012446:Sacroiliac Joint; D01... | Clinical orthopaedics and related research | 1,983 | ||
Evidence that cells from experimental tumours can activate coagulation factor X. | The procoagulant activity of cells from some experimental tumours isolated in culture or in single-cell suspensions from ascitic fluid was investigated. Cells from Lewis lung carcinoma (primary and metastasis), Ehrlich carcinoma ascites and JW sarcoma ascites were able to shorten markedly the recalcification time of no... | 10.1038/bjc.1979.170 | 573,131 | D000818:Animals; D001777:Blood Coagulation; D002286:Carcinoma, Ehrlich Tumor; D005170:Factor X; D006801:Humans; D008175:Lung Neoplasms; D051379:Mice; D008815:Mice, Inbred Strains; D009374:Neoplasms, Experimental; D012510:Sarcoma 180; D013917:Thrombin | British journal of cancer | 1,979 | D005170:Factor X; D013917:Thrombin |
The Responding Site of the Rex Locus of Drosophila melanogaster. | Rex is a dominant, maternal-effect locus in the heterochromatin of the X chromosome Drosophila melanogaster. It causes an early mitotic exchange-like event between heterochromatic elements of an attached- XY in X/attached-XY embryos of Rex mothers. Evidence is presented here that the site of Rex action is the ribosomal... | 10.1093/genetics/115.2.271 | 17,246,364 | Genetics | 1,987 | ||
Factors influencing rearfoot kinematics during a rapid lateral braking movement. | Understanding the morphological, movement, and biomechanical characteristics that influence rearfoot motion during lateral movements is necessary for footwear design and for the determination of injury mechanisms. The purpose of this study was to identify factors related to rearfoot kinematics during a lateral braking ... | 1,569,855 | D001696:Biomechanical Phenomena; D005528:Foot; D006801:Humans; D007700:Kinetics; D008124:Locomotion; D008297:Male; D009068:Movement; D013715:Tennis | Medicine and science in sports and exercise | 1,992 | ||
Aqueous ozone decomposition onto a Co2O3-alumina supported catalyst. | The aqueous ozone decomposition in the presence of a Co2O3-Alumina catalyst was investigated. Activity and estability assays were conducted by reusing the same catalyst in consecutive runs. The catalyst was shown to significantly increase the ozone abatement rate without loss in activity after five consecutive experime... | 15,533,013 | D000537:Aluminum Oxide; D002384:Catalysis; D003035:Cobalt; D007700:Kinetics; D010083:Oxidants, Photochemical; D010087:Oxides; D010126:Ozone; D014865:Waste Disposal, Fluid | Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering | 2,004 | D010083:Oxidants, Photochemical; D010087:Oxides; D003035:Cobalt; D010126:Ozone; D000537:Aluminum Oxide; C060728:cobalt oxide | |
Validating the theoretical structure of the Treatment Self-Regulation Questionnaire (TSRQ) across three different health behaviors. | Nearly 40% of mortality in the United States is linked to social and behavioral factors such as smoking, diet and sedentary lifestyle. Autonomous self-regulation of health-related behaviors is thus an important aspect of human behavior to assess. In 1997, the Behavior Change Consortium (BCC) was formed. Within the BCC,... | 10.1093/her/cyl148 | 17,138,613 | D000293:Adolescent; D000328:Adult; D004032:Diet; D015444:Exercise; D005260:Female; D015438:Health Behavior; D006293:Health Promotion; D006801:Humans; D008297:Male; D009042:Motivation; D015203:Reproducibility of Results; D020377:Self Efficacy; D012907:Smoking; D011795:Surveys and Questionnaires; D014481:United States | Health education research | 2,007 | |
Auditory evoked arousal responses of 3-month-old infants exposed to methamphetamine in utero: a nap study. | AIM
To investigate whether or not infants exposed to methamphetamine prenatally have impaired arousal responses from sleep.
METHODS
The polygraphic nap studies involved 42 infants aged 3 months exposed to methamphetamine in utero and a comparison group of 57 infants. A proportion of mothers in both groups smoked ciga... | 10.1111/apa.12136 | 23,253,105 | D016022:Case-Control Studies; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008470:Meconium; D008694:Methamphetamine; D009520:New Zealand; D017286:Polysomnography; D011247:Pregnancy; D037841:Pregnant Women; D011297:Prenatal Exposure Delayed Effects; D057566:Self Rep... | Acta paediatrica (Oslo, Norway : 1992) | 2,013 | D008694:Methamphetamine |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.