title large_stringlengths 0 979 | abstract large_stringlengths 1 94.7k | doi large_stringlengths 0 71 | pmid int64 21 38.1M | mesh_terms large_stringlengths 0 1.47k | journal large_stringlengths 1 239 | pubdate int16 1.97k 2.02k | chemical_list large_stringlengths 0 1.47k |
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Band shape heterogeneity of the low-energy chlorophylls of CP29: absence of mixed binding sites and excitonic interactions. | A number of spectroscopic characteristics of three almost isoenergetic, red-shifted chlorophylls (chls) in the PS II antenna complex CP29 are investigated with the aim of (i) determining whether their band shapes are substantially identical or not, (ii) addressing the topical problem of whether they are involved in exc... | 10.1021/bi901478f | 20,047,285 | D001059:Apoproteins; D017360:Arabidopsis; D029681:Arabidopsis Proteins; D001665:Binding Sites; D002734:Chlorophyll; D000077194:Chlorophyll A; D060365:Chloroplast Proteins; D004735:Energy Transfer; D045342:Light-Harvesting Protein Complexes; D016297:Mutagenesis, Site-Directed; D045332:Photosystem II Protein Complex; D01... | Biochemistry | 2,010 | D001059:Apoproteins; D029681:Arabidopsis Proteins; C069660:CP29 light harvesting complex; D060365:Chloroplast Proteins; D045342:Light-Harvesting Protein Complexes; D045332:Photosystem II Protein Complex; D010940:Plant Proteins; C529074:RBP29 protein, Arabidopsis; D011994:Recombinant Proteins; D012261:Ribonucleoproteins... |
Pacemaker-neuron-dependent disturbance of the molecular clockwork by a Drosophila CLOCK mutant homologous to the mouse Clock mutation. | Circadian clocks are composed of transcriptional/translational feedback loops (TTFLs) at the cellular level. In Drosophila TTFLs, the transcription factor dCLOCK (dCLK)/CYCLE (CYC) activates clock target gene expression, which is repressed by the physical interaction with PERIOD (PER). Here, we show that amino acids (A... | 10.1073/pnas.1523494113 | 27,489,346 | D000818:Animals; D001683:Biological Clocks; D056926:CLOCK Proteins; D002940:Circadian Rhythm; D004330:Drosophila; D029721:Drosophila Proteins; D051379:Mice; D009154:Mutation; D009474:Neurons; D056950:Period Circadian Proteins; D013696:Temperature | Proceedings of the National Academy of Sciences of the United States of America | 2,016 | C120526:Clk protein, Drosophila; D029721:Drosophila Proteins; D056950:Period Circadian Proteins; C096445:tim protein, Drosophila; D056926:CLOCK Proteins |
Rose Bengal-Mediated Photoinactivation of Multidrug Resistant Pseudomonas aeruginosa Is Enhanced in the Presence of Antimicrobial Peptides. | Due to the overuse of antibiotics in medicine and food production, and their targeted mechanism of action, an increasing rate in spreading of antibiotic resistance genes has been noticed. This results in inefficient therapy outcomes and higher mortality all over the world. Pseudomonas aeruginosa (carbapenem-resistant) ... | 10.3389/fmicb.2018.01949 | 30,177,928 | Frontiers in microbiology | 2,018 | ||
Postal surveys: a review of articles published in the Medical Journal of Malaysia between 1991-2000. | Postal surveys are becoming an increasingly popular method of conducting research in Malaysia. However, the response rates from these surveys have not been well studied. All postal surveys published in the Medical Journal of Malaysia between 1991-2000 were therefore reviewed to provide an overview of the response rates... | 14,569,715 | D006306:Health Surveys; D006801:Humans; D018156:Journalism, Medical; D008296:Malaysia; D010506:Periodicals as Topic; D011177:Postal Service; D015203:Reproducibility of Results; D013997:Time Factors | The Medical journal of Malaysia | 2,002 | ||
Effects of repeated neuropsychological assessments. | The effects of repeated administrations of neuropsychological instruments were evaluated in a group of chronic cigarette smokers who served as control subjects in a larger research project. Subjects performance on 13 neuropsychological variables across four assessments was evaluated using trend analyses. Statistically ... | 14,591,991 | Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists | 1,993 | |||
Comparison of the intubating laryngeal mask airway versus laryngoscopy in the Bell 206-L3 EMS helicopter. | INTRODUCTION
The purpose of this study is to compare intubation success rate and time to intubation for the intubating laryngeal mask airway (I-LMA) versus direct laryngoscopy (DL) using a manikin model during a simulated in-flight scenario.
SETTING
The setting for the study was a University hospital-based air medica... | 10.1016/j.amj.2003.10.008 | 14,760,306 | D017732:Air Ambulances; D006801:Humans; D007442:Intubation, Intratracheal; D017214:Laryngeal Masks; D007828:Laryngoscopy; D018635:Rescue Work; D013997:Time Factors | Air medical journal | 2,004 | |
Electron crystallography of organic materials. | The application of electron crystallography to the study of organic materials is reviewed, mainly in context of the author's own experience. Direct methods for crystallographic phase determination have been shown to be very effective for ab initio structure analyses with electron diffraction intensities, permitting the... | 10.1016/j.ultramic.2006.03.015 | 17,240,070 | D001704:Biopolymers; D003461:Crystallography; D004583:Electrons; D008565:Membrane Proteins; D009930:Organic Chemicals; D010860:Pigments, Biological | Ultramicroscopy | 2,007 | D001704:Biopolymers; D008565:Membrane Proteins; D009930:Organic Chemicals; D010860:Pigments, Biological |
Seasonal Variations of Mercury Levels in Selected Medicinal Plants Originating from Poland. | The presence of mercury in the living cells may be caused by environmental pollution with this element, which is referred to as a toxic xenobiotic. Many literature reports have provided evidence for toxic effects of low levels of mercury in the human body. Therefore, it seems essential to investigate mercury content in... | 10.1007/s12011-016-0645-z | 26,923,864 | D006801:Humans; D008628:Mercury; D018515:Plant Leaves; D010946:Plants, Medicinal; D011044:Poland; D012621:Seasons | Biological trace element research | 2,016 | D008628:Mercury |
Patch-Clamp Recording from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Improving Action Potential Characteristics through Dynamic Clamp. | Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) hold great promise for studying inherited cardiac arrhythmias and developing drug therapies to treat such arrhythmias. Unfortunately, until now, action potential (AP) measurements in hiPSC-CMs have been hampered by the virtual absence of the inward ... | 10.3390/ijms18091873 | 28,867,785 | D000200:Action Potentials; D001145:Arrhythmias, Cardiac; D016275:Atrial Function; D002454:Cell Differentiation; D006352:Heart Ventricles; D006801:Humans; D057026:Induced Pluripotent Stem Cells; D032383:Myocytes, Cardiac; D018408:Patch-Clamp Techniques; D011188:Potassium; D024661:Potassium Channels, Inwardly Rectifying;... | International journal of molecular sciences | 2,017 | D024661:Potassium Channels, Inwardly Rectifying; D014212:Tretinoin; D011188:Potassium |
Contrast enhancement in light microscopy. | The optical microscope is a fundamental component of an image cytometry system. Electronic imaging has both greatly enhanced the capabilities of light microscopes and placed ever-increasing demands on their optical performance. This unit covers the basic concepts of light microscopy, including Köhler illumination, reso... | 10.1002/0471142956.cy0201s00 | 18,770,693 | D000818:Animals; D003287:Contrast Media; D006801:Humans; D019044:Image Cytometry; D008027:Light; D008853:Microscopy; D008856:Microscopy, Fluorescence; D008858:Microscopy, Phase-Contrast; D008859:Microscopy, Polarization; D010825:Physics | Current protocols in cytometry | 2,001 | D003287:Contrast Media |
Ultrafast hydration dynamics in the lipidic cubic phase: Discrete water structures in nanochannels. | We report here our studies of hydration dynamics of confined water in aqueous nanochannels (approximately 50 A) of the lipidic cubic phase. By systematically anchoring the hydrocarbon tails of a series of tryptophan-alkyl ester probes into the lipid bilayer, we mapped out with femtosecond resolution the profile of wate... | 10.1021/jp062806c | 17,064,169 | D008055:Lipids; D015394:Molecular Structure; D049329:Nanostructures; D013050:Spectrometry, Fluorescence; D014867:Water | The journal of physical chemistry. B | 2,006 | D008055:Lipids; D014867:Water |
Neurological melioidosis in Norway presenting with a cerebral abscess. | Neurological melioidosis is a rare condition, as less than 30 cases have been reported in the last 50 years. We present a case of neurological melioidosis, presenting with a cerebral abscess in a returning traveler from an endemic area. While traveling in Cambodia on holiday, the patient was admitted to local hospital ... | 10.1016/j.idcr.2014.11.001 | 26,793,441 | IDCases | 2,015 | ||
Reductive Defluorination and Mechanochemical Decomposition of Per- and Polyfluoroalkyl Substances (PFASs): From Present Knowledge to Future Remediation Concepts. | Over the past two decades, per- and polyfluoroalkyl substances (PFASs) have emerged as worldwide environmental contaminants, calling out for sophisticated treatment, decomposition and remediation strategies. In order to mineralize PFAS pollutants, the incineration of contaminated material is a state-of-the-art process,... | 10.3390/ijerph17197242 | 33,023,008 | D004785:Environmental Pollutants; D052918:Environmental Restoration and Remediation; D005466:Fluorocarbons; D017745:Incineration; D014874:Water Pollutants, Chemical | International journal of environmental research and public health | 2,020 | D004785:Environmental Pollutants; D005466:Fluorocarbons; D014874:Water Pollutants, Chemical |
The Effect of Body Mass Index on Peri-operative Parameters of Total Laparoscopic Hysterectomy: An Institutional Experience. | Objectives Worldwide, there is an increase in the obese population and laparoscopic surgery is now becoming one of the preferred modes of surgery. Therefore, it is important to examine its feasibility and safety in overweight and obese women. The study was aimed to evaluate the effects of body mass index (BMI) on intra... | 10.7759/cureus.15558 | 34,277,181 | Cureus | 2,021 | ||
Feeding behavior comparison of soybean aphid (Hemiptera: Aphididae) biotypes on different soybean genotypes. | Soybean aphids have become a serious pest of soybean, Glycine max L. (Merrill), since they were first detected in North America in 2000. Three soybean aphid biotypes have been documented in the United States in the last 10 yr, but few studies have been done on their feeding behavior in the United States The Electrical ... | 10.1603/ec13126 | 24,224,269 | D000818:Animals; D001042:Aphids; D055590:Electromagnetic Phenomena; D005247:Feeding Behavior; D052585:Phloem; D013025:Glycine max; D014481:United States | Journal of economic entomology | 2,013 | |
An unexpected role for caspase-2 in neuroblastoma. | Caspase-2 has been implicated in various cellular functions, including cell death by apoptosis, oxidative stress response, maintenance of genomic stability and tumor suppression. The loss of the caspase-2 gene (Casp2) enhances oncogene-mediated tumorigenesis induced by E1A/Ras in athymic nude mice, and also in the Eμ-M... | 10.1038/cddis.2014.342 | 25,144,718 | D000818:Animals; D053143:Caspase 2; D004195:Disease Models, Animal; D006801:Humans; D053208:Kaplan-Meier Estimate; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D008822:Mice, Transgenic; D020928:Mitogen-Activated Protein Kinases; D009447:Neuroblastoma; D015398:Signal Transduction; D018631:ras Protei... | Cell death & disease | 2,014 | D020928:Mitogen-Activated Protein Kinases; D053143:Caspase 2; D018631:ras Proteins |
Infant distractibility from social events mediates the relation between maternal responsiveness and infant language outcomes. | Research demonstrates that contingent and appropriate maternal responsiveness to infant requests and bids for attention leads to better language outcomes. Research also indicates that infants who are less distracted by irrelevant competing stimulation and attend efficiently to audiovisual social events (e.g., faces and... | 10.1016/j.infbeh.2023.101840 | 37,210,883 | D005260:Female; D006801:Humans; D007223:Infant; D009034:Mother-Child Relations; D008137:Longitudinal Studies; D009035:Mothers; D007802:Language; D007804:Language Development | Infant behavior & development | 2,023 | |
Anti-annexin 1 antibodies: a new diagnostic marker in the serum of patients with discoid lupus erythematosus. | Annexin 1 is an anti-inflammatory molecule and has also been described to be a common target of autoantibodies. In this study, we determined whether antibodies against annexin 1 can be detected in sera of patients with cutaneous lupus erythematosus (CLE). Levels of anti-annexin 1 antibodies were evaluated by a new esta... | 10.1111/j.1600-0625.2010.01145.x | 20,701,627 | D000328:Adult; D017305:Annexin A1; D001323:Autoantibodies; D015415:Biomarkers; D005260:Female; D006801:Humans; D008179:Lupus Erythematosus, Discoid; D008297:Male; D008875:Middle Aged; D055815:Young Adult | Experimental dermatology | 2,010 | D017305:Annexin A1; D001323:Autoantibodies; D015415:Biomarkers |
Conditioned stress-induced analgesia in humans. | The purpose of this experiment was the demonstration of conditioned stress-induced analgesia in humans. Following a baseline day (day 1), two groups of 10 subjects were each exposed to green light as the conditioned stimulus (CS) and mental arithmetic plus noise as the unconditioned stimulus (US) for 5 days (days 2-6),... | 10.1053/eujp.1999.0137 | 10,700,359 | European journal of pain (London, England) | 1,999 | ||
MATEPRED-A-SVM-Based Prediction Method for Multidrug And Toxin Extrusion (MATE) Proteins. | The growth and spread of drug resistance in bacteria have been well established in both mankind and beasts and thus is a serious public health concern. Due to the increasing problem of drug resistance, control of infectious diseases like diarrhea, pneumonia etc. is becoming more difficult. Hence, it is crucial to under... | 26,256,800 | D000596:Amino Acids; D004151:Dipeptides; D004351:Drug Resistance; D057927:Hydrophobic and Hydrophilic Interactions; D027701:Organic Cation Transport Proteins; D056510:Position-Specific Scoring Matrices; D015203:Reproducibility of Results; D060388:Support Vector Machine | Computational biology and chemistry | 2,015 | D000596:Amino Acids; D004151:Dipeptides; D027701:Organic Cation Transport Proteins | |
Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank. | Alzheimer disease (AD) is the most common dementing illness in the elderly, but there is equivocal evidence regarding the frequency of other disorders such as Lewy body disease (LBD), vascular dementia (VaD), frontotemporal dementia (FTD), and hippocampal sclerosis (HS). This ambiguity may be related to factors such as... | 10.1097/00002093-200210000-00001 | 12,468,894 | D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease; D001344:Autopsy; D018070:Biological Specimen Banks; D003704:Dementia; D015140:Dementia, Vascular; D005260:Female; D005431:Florida; D006624:Hippocampus; D006801:Humans; D015994:Incidence; D020961:Lewy Body Disease; D008297:Male; D008875:Middle Aged; D01... | Alzheimer disease and associated disorders | 2,002 | |
Genetic Risk Factors for Autoimmune Thyroid Disease might Affect the Susceptibility to and Modulate the Progression of Primary Biliary Cholangitis. | BACKGROUND AND AIMS
Patients with primary biliary cholangitis (PBC) frequently suffer from extrahepatic autoimmune conditions, of which autoimmune thyroid disease (AITD) is one of the most common. Previous studies identified several genetic variants increasing the odds of developing AITD. Here we investigate whether AI... | 10.15403/jgld.2014.1121.263.kus | 28,922,436 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002761:Cholangitis; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease; D006801:Humans; D00810... | Journal of gastrointestinal and liver diseases : JGLD | 2,017 | |
Evaluation of high concentration intranasal and intravenous desmopressin in pediatric patients with mild hemophilia A or mild-to-moderate type 1 von Willebrand disease. | OBJECTIVES
The objective of the study was to evaluate the safety and efficacy of high-concentration intranasal desmopressin (HCIN-DDAVP) 1.5 mg/mL, in patients weighing < or = 50 kg with mild hemophilia A or mild type 1 von Willebrand disease (VWD).
STUDY DESIGN
This was a single-center, nonrandomized, open-label, si... | 10.1067/mpd.2002.123626 | 12,032,528 | D000281:Administration, Intranasal; D000293:Adolescent; D000704:Analysis of Variance; D002648:Child; D002675:Child, Preschool; D003894:Deamino Arginine Vasopressin; D005260:Female; D006467:Hemophilia A; D006490:Hemostatics; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D008297:Male; D014842:von Willeb... | The Journal of pediatrics | 2,002 | D006490:Hemostatics; D003894:Deamino Arginine Vasopressin |
The diagnostic value of video capsule endoscopy. | BACKGROUND AND AIMS
Video capsule endoscopy (VCE) offers the best means of studying small bowel, but is expensive. We investigated how physicians appraise the value of VCE.
METHODS
A questionnaire was sent to remitting physicians comprising questions on the value of VCE in altogether 189 adults. The follow-up time wa... | 10.1016/j.ejim.2010.06.014 | 20,816,589 | D015746:Abdominal Pain; D000328:Adult; D000740:Anemia; D001291:Attitude of Health Personnel; D053704:Capsule Endoscopy; D002446:Celiac Disease; D003424:Crohn Disease; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D005762:Gastroenterology; D005767:Gastrointestinal Diseases; D006471:Gastrointestinal Hemorrh... | European journal of internal medicine | 2,010 | |
Cancer risk from bone morphogenetic protein exposure in spinal arthrodesis. | BACKGROUND
The U.S. Food and Drug Administration reported a higher incidence of cancer in patients who had spinal arthrodesis and were exposed to a high dose of recombinant human bone morphogenetic protein-2 (rhBMP-2) compared with the control group in a randomized controlled trial. The purpose of this study was to det... | 10.2106/JBJS.M.01190 | 25,187,579 | D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D016022:Case-Control Studies; D016001:Confidence Intervals; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Stud... | The Journal of bone and joint surgery. American volume | 2,014 | D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D011994:Recombinant Proteins; D016212:Transforming Growth Factor beta; C499469:recombinant human bone morphogenetic protein-2 |
Aptamer-Based Diagnostics and Therapeutics. | Aptamers were first described almost 30 years ago, with the publication of three separate research papers describing how a randomized library of RNA sequences could be incubated with a target to find a sequence that specifically binds via van der Waals forces, covalent and hydrogen bonding, and not Watson Crick base pa... | 10.3390/ph12010006 | 30,609,700 | Pharmaceuticals (Basel, Switzerland) | 2,019 | ||
Improved multi-objective clustering algorithm using particle swarm optimization. | Multi-objective clustering has received widespread attention recently, as it can obtain more accurate and reasonable solution. In this paper, an improved multi-objective clustering framework using particle swarm optimization (IMCPSO) is proposed. Firstly, a novel particle representation for clustering problem is design... | 10.1371/journal.pone.0188815 | 29,206,880 | D000465:Algorithms; D016000:Cluster Analysis; D008962:Models, Theoretical | PloS one | 2,017 | |
Impact of Metformin on IVF Outcomes in Overweight and Obese Women With Polycystic Ovary Syndrome: A Randomized Double-Blind Controlled Trial. | OBJECTIVES
To evaluate the impact of metformin on in vitro fertilization (IVF) outcomes in overweight and obese women with polycystic ovary syndrome (PCOS).
METHODS
This was a randomized double-blind placebo-controlled study ( ClinicalTrials.gov : NCT02910817) carried out in a University IVF Center. The study include... | 10.1177/1933719118765985 | 29,576,001 | D000328:Adult; D004311:Double-Blind Method; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007004:Hypoglycemic Agents; D007247:Infertility, Female; D008687:Metformin; D009765:Obesity; D054315:Oocyte Retrieval; D050177:Overweight; D011085:Polycystic Ovary Syndrome; D016896:Treatment Outcome | Reproductive sciences (Thousand Oaks, Calif.) | 2,019 | D007004:Hypoglycemic Agents; D008687:Metformin |
An essential intermediate in the folding of dihydrofolate reductase. | The folding of Escherichia coli dihydrofolate reductase was examined at pH 7.8 and 15 degrees C by using stopped-flow fluorescence and absorbance spectroscopies. The formation of a highly fluorescent intermediate occurs with relaxation times ranging between 142 and 343 msec, whereas stopped-flow absorbance spectroscopy... | 10.1073/pnas.100547697 | 10,811,909 | D001426:Bacterial Proteins; D004926:Escherichia coli; D008727:Methotrexate; D008958:Models, Molecular; D011485:Protein Binding; D011487:Protein Conformation; D017510:Protein Folding; D013050:Spectrometry, Fluorescence; D013762:Tetrahydrofolate Dehydrogenase | Proceedings of the National Academy of Sciences of the United States of America | 2,000 | D001426:Bacterial Proteins; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate |
Integrin alpha3beta1 is an alternative cellular receptor for adenovirus serotype 5. | Many adenovirus serotypes enter cells by high-affinity binding to the coxsackievirus-adenovirus receptor (CAR) and integrin-mediated internalization. In the present study, we analyzed the possible receptor function of alpha3beta1 for adenovirus serotype 5 (Ad5). We found that penton base and integrin alpha3beta1 could ... | 10.1128/jvi.77.24.13448-13454.2003 | 14,645,603 | D000260:Adenoviruses, Human; D000595:Amino Acid Sequence; D036022:Capsid Proteins; D002460:Cell Line; D006367:HeLa Cells; D006801:Humans; D039201:Integrin alpha3beta1; D008969:Molecular Sequence Data; D019151:Peptide Library; D011991:Receptors, Virus; D012703:Serotyping | Journal of virology | 2,003 | D036022:Capsid Proteins; D039201:Integrin alpha3beta1; D019151:Peptide Library; D011991:Receptors, Virus; C043322:penton protein, adenovirus |
Preparation and immune activity analysis of H5N1 subtype avian influenza virus recombinant protein-based vaccine. | Avian influenza is a severe disease among farmed poultry and free-living birds and a constant threat to the commercial chicken industry around the world. Hemagglutinin (HA) is the major immunogen on the envelope of influenza A virus and is the predominant inducer of neutralizing antibody. To obtain the bioactive antige... | 10.3382/ps.2009-00092 | 19,590,075 | D000818:Animals; D000911:Antibodies, Monoclonal; D001425:Bacterial Outer Membrane Proteins; D002645:Chickens; D029968:Escherichia coli Proteins; D006385:Hemagglutination Inhibition Tests; D006388:Hemagglutinins; D053124:Influenza A Virus, H5N1 Subtype; D007252:Influenza Vaccines; D005585:Influenza in Birds; D010957:Pla... | Poultry science | 2,009 | D000911:Antibodies, Monoclonal; D001425:Bacterial Outer Membrane Proteins; D029968:Escherichia coli Proteins; D006388:Hemagglutinins; D007252:Influenza Vaccines; D011994:Recombinant Proteins; C073124:msyB protein, E coli |
The relationship between prostate volume and prostate-specific antigen variability: data from the Baltimore Longitudinal Study of Aging and the Johns Hopkins Active Surveillance Program. | UNLABELLED
Study Type--Prognostic (cohort). Level of Evidence 2b. What's known on the subject? And what does the study add? Previous studies have attempted to characterize the normal biological variability in PSA among men without prostate cancer. These reports suggest that PSA variability is unrelated to age, but ther... | 10.1111/j.1464-410X.2011.10663.x | 22,093,443 | D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011467:Prostate; D017430:Prostate-Specific Antigen; D011471:Prostatic Neoplasms; D012016:Reference Values | BJU international | 2,012 | D017430:Prostate-Specific Antigen |
Seasonal and pandemic influenza preparedness: a global threat. | The increase in the incidence of avian influenza worldwide in both poultry and humans introduces the potential for another influenza A pandemic that could pose a significant threat to both human health and the global economy. The impact of the next influenza pandemic will be influenced, in part, by how well the medical... | 10.1086/507562 | 17,163,390 | D000818:Animals; D004196:Disease Outbreaks; D006078:Government Programs; D006285:Health Planning; D006801:Humans; D009980:Influenza A virus; D007252:Influenza Vaccines; D007251:Influenza, Human; D011322:Primary Prevention; D012621:Seasons; D014481:United States | The Journal of infectious diseases | 2,006 | D007252:Influenza Vaccines |
Advanced Multimaterial Electronic and Optoelectronic Fibers and Textiles. | The ability to integrate complex electronic and optoelectronic functionalities within soft and thin fibers is one of today's key advanced manufacturing challenges. Multifunctional and connected fiber devices will be at the heart of the development of smart textiles and wearable devices. These devices also offer novel o... | 10.1002/adma.201802348 | 30,272,829 | Advanced materials (Deerfield Beach, Fla.) | 2,019 | ||
Identification and characterization of a calcium dependent bacillopeptidase from Bacillus subtilis CFR5 with novel kunitz trypsin inhibitor degradation activity. | The cereals and pulses are considered to be an important component in the food chain due to their proteinaceous nature, but the presence of anti-nutritional factors (KTI) decreases their nutrient absorption rate. Kunitz trypsin inhibitors (KTI) reduce the bioavailability of trypsin and are the primary cause for the exi... | 10.1016/j.foodres.2017.10.049 | 29,389,614 | D001412:Bacillus subtilis; D001426:Bacterial Proteins; D002118:Calcium; D003001:Cloning, Molecular; D004795:Enzyme Stability; D005516:Food Microbiology; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D009154:Mutation; D010447:Peptide Hydrolases; D011487:Protein Conformation; D059748:Proteolysis; D013329:Structur... | Food research international (Ottawa, Ont.) | 2,018 | D001426:Bacterial Proteins; D014360:Trypsin Inhibitor, Kunitz Soybean; D010447:Peptide Hydrolases; D002118:Calcium |
Sulfur-containing gaseous signal molecules, ion channels and cardiovascular diseases. | Sulfur-containing gaseous signal molecules including hydrogen sulphide and sulfur dioxide were previously recognized as toxic gases. However, extensive studies have revealed that they can be generated in the cardiovascular system via a sulfur-containing amino acid metabolic pathway, and have an important role in cardio... | 10.1111/bph.13829 | 28,430,359 | D000818:Animals; D002318:Cardiovascular Diseases; D006801:Humans; D006862:Hydrogen Sulfide; D007473:Ion Channels; D013458:Sulfur Dioxide | British journal of pharmacology | 2,018 | D007473:Ion Channels; D013458:Sulfur Dioxide; D006862:Hydrogen Sulfide |
Art, Design and Communication Theory in Creating the Communicative Social Robot 'Haru'. | Haru is a social, affective robot designed to support a wide range of research into human-robot communication. This article analyses the design process for Haru beta, identifying how both visual and performing arts were an essential part of that process, contributing to ideas of Haru's communication as a science and as... | 10.3389/frobt.2021.577107 | 33,816,565 | Frontiers in robotics and AI | 2,021 | ||
CO2 and O2 distribution in Rubisco suggests the small subunit functions as a CO2 reservoir. | Protein-gas interactions are important in biology. The enzyme ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) catalyzes two competing reactions involving CO2 and O2 as substrates. Carboxylation of the common substrate ribulose-1,5-bisphosphate leads to photosynthetic carbon assimilation, while the oxygenation... | 10.1021/ja411579b | 24,495,214 | D002245:Carbon Dioxide; D020134:Catalytic Domain; D008958:Models, Molecular; D056004:Molecular Dynamics Simulation; D010100:Oxygen; D010788:Photosynthesis; D012273:Ribulose-Bisphosphate Carboxylase; D012274:Ribulosephosphates | Journal of the American Chemical Society | 2,014 | D012274:Ribulosephosphates; D002245:Carbon Dioxide; C001933:ribulose-1,5 diphosphate; D012273:Ribulose-Bisphosphate Carboxylase; D010100:Oxygen |
Prevalence of erosive lesions with respect to risk factors in a young adult population in Poland-a cross-sectional study. | OBJECTIVE
The study was conducted to investigate the prevalence of erosive lesions and related risk factors in the population of 18-year-old young adults in Poland.
MATERIALS AND METHODS
Calibrated examiners measured erosive tooth wear according to Basic Erosive Wear Examination (BEWE) scoring system in 1869 patients... | 10.1007/s00784-016-2012-z | 27,981,411 | D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D011044:Poland; D015995:Prevalence; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014077:Tooth Erosion | Clinical oral investigations | 2,017 | |
The Motor Function Evaluation of College Students' Physical Activity State From the Perspective of Educational Psychology. | College students have taken part in less and less physical activities as a result of the common static lifestyle in recent years, lowering the level of motor function. This phenomenon has been a source of concern for schools and the government, and it is necessary to take corresponding measures to change it. The genera... | 10.3389/fpsyg.2021.593285 | 33,935,853 | Frontiers in psychology | 2,021 | ||
Synaptic Communication in Diverse Astrocytic Connectivity: A Computational Model. | Astrocytes are recently considered active components in neural communication by modulating tripartite synaptic activity and the signaling mechanism facilitated by intercellular calcium wave (ICW) propagation. The heterogeneity in astrocytic connectivity produces diverse spatiotemporal signals equating to a diverse infl... | 10.1109/EMBC48229.2022.9871642 | 36,085,820 | D001253:Astrocytes; D020013:Calcium Signaling; D003142:Communication; D017629:Gap Junctions; D018698:Glutamic Acid | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 2,022 | D018698:Glutamic Acid |
Alternative splicing yields novel BMAL2 variants: tissue distribution and functional characterization. | The BMAL2 gene encodes a member of the basic helix-loop-helix PER-ARNT-SIM family of transcription factors, which control diverse physiological processes including circadian rhythms. We identified four novel human BMAL2 transcripts that differ by alternative splicing within their NH2-terminal regions. Divergent express... | 10.1152/ajpcell.00541.2001 | 12,055,078 | D056930:ARNTL Transcription Factors; D017398:Alternative Splicing; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D051792:Basic Helix-Loop-Helix Transcription Factors; D056926:CLOCK Proteins; D002417:Cattle; D018797:Cell Cycle Proteins; D002478:Cells, Cultured; D002940:Circadian Rhythm; D056931:Cr... | American journal of physiology. Cell physiology | 2,002 | D056930:ARNTL Transcription Factors; C486615:BMAL2 protein, human; C431792:Arntl2 protein, mouse; D051792:Basic Helix-Loop-Helix Transcription Factors; D018797:Cell Cycle Proteins; D056931:Cryptochromes; D029721:Drosophila Proteins; D005136:Eye Proteins; D005420:Flavoproteins; D009687:Nuclear Proteins; C539022:PER1 pro... |
Kaposi's sarcoma in an atopic dermatitis patient: a case report and a review of literature. | A 7-year-old girl suffering from atopic dermatitis developed multiple lesions of Kaposi's sarcoma, which could not be categorized under any one of the four known types of Kaposi's sarcoma (classic, human immunodeficiency virus-associated, endemic, or iatrogenic). We propose that atopic dermatitis may cause susceptibili... | 10.1111/j.1525-1470.2011.01347.x | 21,385,206 | D001706:Biopsy; D002648:Child; D003876:Dermatitis, Atopic; D005260:Female; D019288:Herpesvirus 8, Human; D006801:Humans; D007073:Immunoglobulin E; D012514:Sarcoma, Kaposi; D012878:Skin Neoplasms; D016896:Treatment Outcome | Pediatric dermatology | 2,011 | D007073:Immunoglobulin E |
Cloning and sequencing of a Candida albicans catalase gene and effects of disruption of this gene. | Catalase plays a key role as an antioxidant, protecting aerobic organisms from the toxic effects of hydrogen peroxide, and in some cases has been postulated to be a virulence factor. To help elucidate the function of catalase in Candida albicans, a single C. albicans-derived catalase gene, designated CAT1, was isolated... | 10.1128/IAI.66.5.1953-1961.1998 | 9,573,075 | D000595:Amino Acid Sequence; D000818:Animals; D015152:Blotting, Northern; D015139:Blotting, Southern; D002176:Candida albicans; D002177:Candidiasis; D002374:Catalase; D003001:Cloning, Molecular; D005800:Genes, Fungal; D006801:Humans; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D008969:Molecular Sequence Data;... | Infection and immunity | 1,998 | D002374:Catalase |
Antenatal corticosteroid therapy in premature infants. | OBJECTIVE
The objective was to examine the effect of antenatal corticosteroid treatment on premature infants, with special attention to any possible adverse effects on neonatal outcome.
METHODS
A retrospective chart review of all singleton and multiple pregnancies delivered in our perinatal center between 1991 and 19... | 10.1007/s00404-004-0664-4 | 15,309,401 | D000305:Adrenal Cortex Hormones; D002543:Cerebral Hemorrhage; D002821:Chorioamnionitis; D005260:Female; D005322:Fetal Membranes, Premature Rupture; D005865:Gestational Age; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007234:Infant, Premature; D007969:Leukomalacia, Periventricular; D008297:Male; ... | Archives of gynecology and obstetrics | 2,005 | D000305:Adrenal Cortex Hormones |
Dynamics of plasmodesmal connectivity in successive interfaces of the cambial zone. | Frequency, density and branching of plasmodesmata were counted in successive tangential and transverse walls in the cambial zone of tomato stems in order to examine development of the plasmodesmal network in a chronological order. Coincident with progress of cell development, plasmodesmal connectivity increased, both a... | 10.1007/s00425-009-1046-8 | 19,936,780 | D002455:Cell Division; D002473:Cell Wall; D006861:Hydrogen Peroxide; D007150:Immunohistochemistry; D018551:Solanum lycopersicum; D009195:Peroxidase; D052585:Phloem; D031425:Plasmodesmata; D052584:Xylem | Planta | 2,010 | D006861:Hydrogen Peroxide; D009195:Peroxidase |
Primary isoniazid prophylaxis against tuberculosis in HIV-exposed children. | BACKGROUND
The dual epidemic of human immunodeficiency virus (HIV) and tuberculosis is a major cause of sickness and death in sub-Saharan Africa. We conducted a double-blind, randomized, placebo-controlled trial of preexposure isoniazid prophylaxis against tuberculosis in HIV-infected children and uninfected children e... | 10.1056/NEJMoa1011214 | 21,732,834 | D017088:AIDS-Related Opportunistic Infections; D000995:Antitubercular Agents; D004311:Double-Blind Method; D024881:Drug Resistance, Bacterial; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections; D015497:HIV-1; D006801:Humans; D007223:Infant; D057194:Intention to Treat Analysis; D007538:Isoniazid; D053208... | The New England journal of medicine | 2,011 | D000995:Antitubercular Agents; D007538:Isoniazid |
Plexiform angiomyxoid myofibroblastic tumour: differential diagnosis of gastrointestinal stromal tumour in the stomach. | Mesenchymal tumours other than gastrointestinal stromal tumours are rare in the stomach. Nevertheless it is important to incorporate them into the differential diagnosis. Plexiform angiomyxoid myofibroblastic tumour is a recently described new entity of a presumably benign mesenchymal gastric tumour. This report presen... | 10.1136/jcp.2008.059162 | 18,820,104 | D004252:DNA Mutational Analysis; D003937:Diagnosis, Differential; D005260:Female; D046152:Gastrointestinal Stromal Tumors; D006801:Humans; D007150:Immunohistochemistry; D008637:Mesenchymoma; D008875:Middle Aged; D047708:Myofibroma; D009232:Myxoma; D013274:Stomach Neoplasms | Journal of clinical pathology | 2,008 | |
Preservation of the dentition following removal of a central giant cell granuloma: a case presentation. | Clinical and radiographic presentation of a child with central giant cell granuloma in the early mixed dentition and a suggested conservative management technique for preserving the developing dentition is presented. | 10,709,541 | D002648:Child; D003818:Dentition, Mixed; D006101:Granuloma, Giant Cell; D006801:Humans; D008297:Male; D008336:Mandibular Diseases; D016388:Tooth Loss | The Journal of clinical pediatric dentistry | 1,999 | ||
Jet-cooled vibronic spectroscopy of potential intermediates along the pathway to PAH: phenylcyclopenta-1,3-diene. | The vibronic excitation spectrum of phenylcyclopenta-1,3-diene (PCP3D) has been recorded in a supersonic expansion using resonant-two-photon ionization (R2PI) and laser-induced fluorescence (LIF) techniques. The spectrum is dominated by the S(0)-S(1) origin transition (31,739 cm(-1)), with several low-frequency vibroni... | 10.1039/b903827b | 19,756,288 | Physical chemistry chemical physics : PCCP | 2,009 | ||
Pulmonary vein antrum isolation, atrioventricular junction ablation, and antiarrhythmic drugs combined with direct current cardioversion: survival rates at 7 years follow-up. | PURPOSE
To report survival rates in patients treated with pulmonary vein antrum isolation (PVAI), atrioventricular junctional ablation (AVJA), and antiarrhythmic and direct current cardioversion (A+DCCV) at 7 years follow-up.
METHODS
From February 2002-December 2004, 1,000 consecutive patients underwent PVAI or A+DCC... | 10.1007/s10840-009-9436-1 | 19,789,970 | D000368:Aged; D000889:Anti-Arrhythmia Agents; D001281:Atrial Fibrillation; D001283:Atrioventricular Node; D003131:Combined Modality Therapy; D015897:Comorbidity; D004554:Electric Countershock; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009820:Ohio; D015995:Prevalence; D011667:Pulmona... | Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing | 2,009 | D000889:Anti-Arrhythmia Agents |
Functional human CFTR produced by a stable minichromosome. | Artificial chromosomes have been claimed to be the ideal vector for gene therapy, but their use has been hampered by an inability to produce stable and well designed molecules. We have used a structurally defined minichromosome to clone the human cystic fybrosis transmembrane conductance regulator (CFTR) locus. To guar... | 10.1093/embo-reports/kvf174 | 12,189,175 | D000818:Animals; D016466:CHO Cells; D002713:Chlorine; D002875:Chromosomes; D018244:Chromosomes, Artificial, Yeast; D003001:Cloning, Molecular; D006224:Cricetinae; D000242:Cyclic AMP; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D005821:Genetic Techniques; D015316:Genetic Therapy; D006801:Humans; D017404... | EMBO reports | 2,002 | C505032:CFTR protein, human; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D002713:Chlorine; D000242:Cyclic AMP; D001616:beta-Galactosidase |
Exploiting Electrocorticographic Spectral Characteristics for Optimized Signal Chain Design: A 1.08 Analog Front End With Reduced ADC Resolution Requirements. | Electrocorticography (ECoG) is an important area of research for Brain-Computer Interface (BCI) development. ECoG, along with some other biopotentials, has spectral characteristics that can be exploited for more optimal front-end performance than is achievable with conventional techniques. This paper optimizes noise pe... | 10.1109/TBCAS.2016.2518923 | 27,071,192 | D000669:Amplifiers, Electronic; D062207:Brain-Computer Interfaces; D000069280:Electrocorticography; D004867:Equipment Design; D006801:Humans; D012815:Signal Processing, Computer-Assisted; D059629:Signal-To-Noise Ratio | IEEE transactions on biomedical circuits and systems | 2,016 | |
A Novel Method for Studying the Pharmacokinetics of [(14) C]Umeclidinium After Application to the Axilla or Palm of Healthy Male Subjects. | Umeclidinium (UMEC), a long-acting muscarinic antagonist approved for chronic obstructive pulmonary disease (COPD), was investigated for primary hyperhidrosis as topical therapy. This study evaluated the pharmacokinetics, safety, and tolerability of a single dose of [(14) C]UMEC applied to either unoccluded axilla (UA)... | 10.1111/cts.12406 | 27,304,394 | D000280:Administration, Inhalation; D000328:Adult; D001365:Axilla; D002250:Carbon Radioisotopes; D003710:Demography; D004305:Dose-Response Relationship, Drug; D004333:Drug Administration Routes; D006225:Hand; D006801:Humans; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D011812:Quinuclidines; D011851:R... | Clinical and translational science | 2,016 | D002250:Carbon Radioisotopes; C573971:GSK573719; D011812:Quinuclidines |
Actinic cheilitis in dental practice. | Actinic cheilitis is a potentially premalignant condition involving predominantly the vermilion of the lower lip. The aim of the current paper was to review the clinical presentation of actinic cheilitis and demonstrate the development of management plans using a series of cases. These are designed to provide immediate... | 10.1111/j.1834-7819.2010.01202.x | 20,553,248 | D000293:Adolescent; D002613:Cheilitis; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D006801:Humans; D007972:Leukoplakia, Oral; D008019:Life Style; D008046:Lip; D008048:Lip Neoplasms; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced; D011230:Precancerous Conditions... | Australian dental journal | 2,010 | D013473:Sunscreening Agents |
Altered blood pressure and renin responses to converting enzyme inhibition after aprotinin-induced kallikrein-kinin-system blockade. | 1. The effect of aprotinin-induced blockade of the kallikrein-kinin system on haemodynamic and biochemical responses to converting enzyme inhibition by SQ 14 225 was evaluated in 26 patients with essential hypertension. 2. SQ 14 225 lowered blood pressure in high, normal and low renin hypertension. In low and normal re... | 10.1042/cs059129s | 6,160,938 | D000450:Aldosterone; D000804:Angiotensin II; D007611:Aprotinin; D001794:Blood Pressure; D002216:Captopril; D006801:Humans; D006973:Hypertension; D007703:Peptidyl-Dipeptidase A; D011392:Proline; D012083:Renin | Clinical science (London, England : 1979) | 1,980 | D000804:Angiotensin II; D000450:Aldosterone; D007611:Aprotinin; D011392:Proline; D002216:Captopril; D007703:Peptidyl-Dipeptidase A; D012083:Renin |
Vapor Growth and Tunable Lasing of Band Gap Engineered Cesium Lead Halide Perovskite Micro/Nanorods with Triangular Cross Section. | Although great efforts have been devoted to the synthesis of halide perovskites nanostructures, vapor growth of high-quality one-dimensional cesium lead halide nanostructures for tunable nanoscale lasers is still a challenge. Here, we report the growth of high-quality all-inorganic cesium lead halide alloy perovskite m... | 10.1021/acsnano.6b07374 | 28,035,809 | ACS nano | 2,017 | ||
Laparoscopic-assisted ovariohysterectomy for the treatment of pyometra in a Bengal tiger (Panthera tigris tigris). | A laparoscopic-assisted ovariohysterectomy was performed in a 19-year-old intact, female Bengal tiger (Panthera tigris tigris) presented for surgical treatment of pyometra. A multi-port technique was used with intra-corporeal sealing of the ovarian pedicles and extra-corporeal ligation of the uterine vessels and body. ... | 30,104,782 | D000820:Animal Diseases; D000818:Animals; D005260:Female; D007044:Hysterectomy; D010535:Laparoscopy; D010052:Ovariectomy; D055112:Pyometra; D046010:Tigers | The Canadian veterinary journal = La revue veterinaire canadienne | 2,018 | ||
Association between sexual maturation and anterior disc displacement of temporomandibular joint in adolescents aged 13-14 years. | OBJECTIVES
To investigate the association between sexual maturation and anterior disc displacement (ADD) of temporomandibular joint (TMJ).
MATERIALS AND METHODS
Adolescents aged 13-14 years old, attending the first grade of one private junior school, were recruited. Magnetic resonance imaging (MRI) was used to confir... | 10.1007/s00784-022-04667-8 | 36,102,990 | D008297:Male; D005260:Female; D000293:Adolescent; D006801:Humans; D019224:Temporomandibular Joint Disc; D012741:Sexual Maturation; D011388:Prolactin; D004204:Joint Dislocations; D013704:Temporomandibular Joint; D008279:Magnetic Resonance Imaging; D013739:Testosterone | Clinical oral investigations | 2,022 | D011388:Prolactin; D013739:Testosterone |
Antibacterial activity of bile salts against common biliary pathogens. Effects of hydrophobicity of the molecule and in the presence of phospholipids. | In vitro studies have demonstrated that bile salts have cytotoxic and bacteriostatic properties. The cytotoxic effect of bile salts is reduced when lecithin is added. The effect of lecithin on the bacteriostatic property of bile salts is not known. In this report, we test the hypotheses that (1) the bacteriostatic acti... | 10.1007/BF01297092 | 8,223,087 | D001646:Bile; D001647:Bile Acids and Salts; D013293:Enterococcus faecalis; D004926:Escherichia coli; D006801:Humans; D008854:Microscopy, Electron; D010713:Phosphatidylcholines; D014867:Water | Digestive diseases and sciences | 1,993 | D001647:Bile Acids and Salts; D010713:Phosphatidylcholines; D014867:Water |
Pre-existing tumor host immunity characterization in resected non-small cell lung cancer. | INTRODUCTION
Neoadjuvant and adjuvant immune checkpoint blockade (ICB) have recently become standard of care in resectable non-small cell lung cancer (NSCLC). Yet, biomarkers that inform patients who benefit from this approach remain largely unknown. Here, we interrogated the tumor immune microenvironment (TIME) in ear... | 10.1016/j.lungcan.2023.107257 | 37,263,182 | D006801:Humans; D002289:Carcinoma, Non-Small-Cell Lung; D008175:Lung Neoplasms; D060890:B7-H1 Antigen; D000077192:Adenocarcinoma of Lung; D015415:Biomarkers; D051858:Forkhead Transcription Factors; D014408:Biomarkers, Tumor; D059016:Tumor Microenvironment; D016246:Lymphocytes, Tumor-Infiltrating | Lung cancer (Amsterdam, Netherlands) | 2,023 | D060890:B7-H1 Antigen; D015415:Biomarkers; D051858:Forkhead Transcription Factors; D014408:Biomarkers, Tumor |
Analysis of the phytochemical contents and antioxidant activities of crude extracts from Tulbaghia species. | OBJECTIVE
To assess the phytochemical contents and antioxidant activities of crude extracts from selected Tulbaghia species.
METHODS
Standard methods were used for preliminary phytochemical analysis. The total phenolic acid contents of the plant extracts were determined using the Folin-Ciocalteu method, and the total... | 32,186,066 | Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan | 2,018 | |||
Validity and reproducibility of histologic diagnosis and grading for adult soft-tissue sarcomas. | Soft-tissue sarcomas in adults show great variations in histologic type and grade. A valid and reproducible prognostication system is needed to select patients with soft-tissue sarcomas who could benefit from adjuvant chemotherapy. This study was conducted to assess the validity and reproducibility of diagnosis of the ... | 10.1053/hupa.2002.30184 | 11,823,981 | D034961:Antigens, Nuclear; D006801:Humans; D019394:Ki-67 Antigen; D008938:Mitosis; D009687:Nuclear Proteins; D015588:Observer Variation; D011379:Prognosis; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012509:Sarcoma; D012680:Sensitivity and Specificity; D012983:Soft Tissue Neoplasms | Human pathology | 2,002 | D034961:Antigens, Nuclear; D019394:Ki-67 Antigen; D009687:Nuclear Proteins |
'Hu Hong' (bad thing): parental perceptions of teenagers' sexuality in urban Vietnam. | BACKGROUND
Teenagers under 18 years old in Vietnam are considered as minors who usually lack the autonomy to make decisions. They are also sometimes viewed as contributors to social evils including crime, violence and substance use. Moreover, most Vietnamese teenagers have unsafe sex before marriage. The objective of t... | 10.1186/s12889-017-4133-y | 28,245,806 | D000293:Adolescent; D000294:Adolescent Behavior; D003268:Contraception Behavior; D005260:Female; D006801:Humans; D008297:Male; D009035:Mothers; D010287:Parent-Child Relations; D000297:Psychology, Adolescent; D012736:Sex Education; D012725:Sexual Behavior; D014744:Vietnam | BMC public health | 2,017 | |
[Reflux nephropathy within first year of life. Studies of its clinical features and kidney scar-formation according to treatment modalities]. | Clinical data of 106 patients (177 renal units) with vesicoureteral reflux diagnosed within first year of life were reviewed to clarify its clinical feature and reflux nephropathy. 1) 82.1% (87/106) of them were boy, 83.1% (147/177) of renal units had high grade reflux (VUR grade III or more). These findings suggested ... | 10.5980/jpnjurol1989.85.738 | 8,022,135 | D002921:Cicatrix; D005260:Female; D006801:Humans; D007223:Infant; D007674:Kidney Diseases; D008297:Male; D014718:Vesico-Ureteral Reflux | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology | 1,994 | |
Multiple-aetiology enteric infections involving non-O157 Shiga toxin-producing Escherichia coli--FoodNet, 2001-2010. | We describe multiple-aetiology infections involving non-O157 Shiga toxin-producing Escherichia coli (STEC) identified through laboratory-based surveillance in nine FoodNet sites from 2001 to 2010. A multiple-aetiology infection (MEI) was defined as isolation of non-O157 STEC and laboratory evidence of any of the other ... | 10.1111/zph.12098 | 24,484,079 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D000829:Animals, Domestic; D002169:Campylobacter Infections; D002648:Child; D002675:Child, Preschool; D003457:Cryptosporidiosis; D004927:Escherichia coli Infections; D019453:Escherichia coli O157; D005260:Female; D006801:Humans... | Zoonoses and public health | 2,014 | D022621:Shiga Toxin |
[Advances in research of volatile oil and its different chemotypes in leaves of Perilla frutescens]. | The volatile oil is the main component in the leaves of Perilla frutescens. According to the main types of monoterpenoids or aromatic compounds, it can be divided into different chemotypes and the main chemotypes of Chinese producing Perilla are PA type (mainly containing Perilla aldehyde and limonene), PK type (mainly... | 26,677,690 | D000818:Animals; D006801:Humans; D009822:Oils, Volatile; D031344:Perilla frutescens; D018515:Plant Leaves | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica | 2,015 | D009822:Oils, Volatile | |
E-BiInSn Enhanced Rigidity Alterable Artificial Bandage. | surgery, orthopedic cast is often implemented to stabilize and fix anatomical structures like broken bones. Plaster could harden after mixed with water, thus it is commonly utilized with cotton bandage to form a solid structure to encase a limb or other body parts. As plaster is heavy and impervious, cast could easily ... | 10.1109/EMBC.2018.8512906 | 30,441,001 | D001458:Bandages; D012867:Skin | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 2,018 | |
Altered cortical structure and psychiatric symptom risk in adolescents exposed to maternal stress in utero: A retrospective investigation. | Maternal exposure to stress during pregnancy is associated with increased risk for cognitive and behavioral sequelae in offspring. Animal research demonstrates exposure to stress during gestation has effects on brain structure. In humans, however, little is known about the enduring effects of in utero exposure to mater... | 10.1016/j.bbr.2019.112145 | 31,400,378 | D000293:Adolescent; D000328:Adult; D001921:Brain; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018811:Maternal Exposure; D009035:Mothers; D010296:Parietal Lobe; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011446:Prospective Studies; D012189:Retrosp... | Behavioural brain research | 2,019 | |
Oncolytic Herpes Simplex Virus Encoding IL12 Controls Triple-Negative Breast Cancer Growth and Metastasis. | Triple-negative breast cancer (TNBC) is a difficult-to-treat disease with high rates of local recurrence, distant metastasis, and poor overall survival with existing therapies. Thus, there is an unmet medical need to develop new treatment regimen(s) for TNBC patients. An oncolytic herpes simplex virus encoding a master... | 10.3389/fonc.2020.00384 | 32,266,155 | Frontiers in oncology | 2,020 | ||
Endoscopic submucosal dissection of squamous cell carcinoma in the upper stomach 5 years after chemoradiotherapy for adenocarcinoma. | Primary squamous cell carcinoma is rarely observed, with a reported incidence of 0.04-0.07 % of all gastric cancers. An 81-year-old male underwent chemoradiotherapy for type 1 gastric cancer of the posterior wall of the cardiac region in 2005. The tumor disappeared after 1 year of therapy, following which an area of wh... | 10.1007/s12328-014-0503-5 | 26,185,878 | D000230:Adenocarcinoma; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell; D059248:Chemoradiotherapy; D004210:Dissection; D005753:Gastric Mucosa; D005773:Gastroscopy; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary; D013274:Stomach Neoplasms; D013997:Time Factors | Clinical journal of gastroenterology | 2,014 | |
Characterizing the swimming properties of artificial bacterial flagella. | Artificial bacterial flagella (ABFs) consist of helical tails resembling natural flagella fabricated by the self-scrolling of helical nanobelts and soft-magnetic heads composed of Cr/Ni/Au stacked thin films. ABFs are controlled wirelessly using a low-strength rotating magnetic field. Self-propelled devices such as the... | 10.1021/nl901869j | 19,824,709 | D002857:Chromium; D005407:Flagella; D006046:Gold; D008280:Magnetics; D008954:Models, Biological; D009532:Nickel; D013499:Surface Properties; D013550:Swimming | Nano letters | 2,009 | D002857:Chromium; D006046:Gold; D009532:Nickel |
Blood pressure following microinjection of somatostatin related peptides into the rat nucleus tractus solitarii. | The possible role of medullary somatostatin as a neurotransmitter involved in blood pressure regulation was examined. Blood pressure and heart rate were measured in pentobarbital anesthetized rats while pmol quantities of somatostatin-28 (SS28), SS28-(15-28) (somatostatin-14), SS28-(1-12) or SS28-(1-10) were injected i... | 10.1016/0014-2999(85)90091-3 | 2,864,269 | D000818:Animals; D001794:Blood Pressure; D006339:Heart Rate; D008297:Male; D008526:Medulla Oblongata; D008845:Microinjections; D019832:N-Methylscopolamine; D051381:Rats; D011919:Rats, Inbred Strains; D012602:Scopolamine Derivatives; D013004:Somatostatin; D053561:Somatostatin-28; D014043:Tolazoline; D015016:Yohimbine | European journal of pharmacology | 1,985 | D012602:Scopolamine Derivatives; D015016:Yohimbine; D013004:Somatostatin; D053561:Somatostatin-28; D014043:Tolazoline; D019832:N-Methylscopolamine |
Strategy of accelerated method development for high-throughput bioanalytical assays using ultra high-performance liquid chromatography coupled with mass spectrometry. | Here we report a strategy for rapid method development of high-throughput bioanalytical assays using ultra high-performance liquid chromatography coupled with tandem mass spectrometry (uHPLC-MS/MS). First, a data set was established for the removal of representative phospholipids under different sample treatments to gu... | 10.1021/ac901316w | 19,856,950 | D000935:Antifungal Agents; D002623:Chemistry Techniques, Analytical; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D007654:Ketoconazole; D053719:Tandem Mass Spectrometry | Analytical chemistry | 2,009 | D000935:Antifungal Agents; D007654:Ketoconazole |
Social-capital-based mental health interventions for refugees: A systematic review. | With over 80 million people forcibly displaced worldwide, providing safe, healthy, and supportive places for refugees has become an imperative for national governments, aid organizations, and host communities. While much has been written about the needs of these displaced people, organizations and practitioners tend to... | 10.1016/j.socscimed.2022.114787 | 35,366,460 | D006304:Health Status; D006801:Humans; D001523:Mental Disorders; D008603:Mental Health; D012036:Refugees; D066270:Social Capital | Social science & medicine (1982) | 2,022 | |
Long-term maintenance of multidrug-resistant Escherichia coli carried by vampire bats and shared with livestock in Peru. | Extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-E. coli) have been reported in wildlife worldwide. Whether wildlife is a transient host of ESBL-E. coli or comprises an independently maintained reservoir is unknown. We investigated this question by longitudinally monitoring ESBL-E. coli in common vampi... | 10.1016/j.scitotenv.2021.152045 | 34,883,172 | D000818:Animals; D000900:Anti-Bacterial Agents; D002685:Chiroptera; D004926:Escherichia coli; D029968:Escherichia coli Proteins; D058751:Livestock; D010568:Peru; D010957:Plasmids; D013552:Swine; D001618:beta-Lactamases | The Science of the total environment | 2,022 | D000900:Anti-Bacterial Agents; D029968:Escherichia coli Proteins; C000614037:MCR-1 protein, E coli; D001618:beta-Lactamases |
Real-world lessons from the implementation of a depression screening protocol in acute myocardial infarction patients: implications for the American Heart Association depression screening advisory. | BACKGROUND
The American Heart Association (AHA) statement has recommended routine screening for depression in coronary artery disease with a 2-stage implementation of the Patient Health Questionnaire (PHQ). Because there is little evidence on feasibility, accuracy, and impact of such a program on depression recognition... | 10.1161/CIRCOUTCOMES.110.960013 | 21,505,152 | D000368:Aged; D000572:American Heart Association; D003863:Depression; D005260:Female; D019983:Guideline Adherence; D006801:Humans; D015994:Incidence; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D009203:Myocardial Infarction; D012042:Registries; D012307:Risk Factors; D011795:Surveys and Questionnaires; D0... | Circulation. Cardiovascular quality and outcomes | 2,011 | |
Stable organic electrochemical neurons based on p-type and n-type ladder polymers. | Organic electrochemical transistors (OECTs) are a rapidly advancing technology that plays a crucial role in the development of next-generation bioelectronic devices. Recent advances in p-type/n-type organic mixed ionic-electronic conductors (OMIECs) have enabled power-efficient complementary OECT technologies for vario... | 10.1039/d3mh00858d | 37,477,499 | Materials horizons | 2,023 | ||
Generation of reactive oxygen species by equine spermatozoa. | OBJECTIVE
To characterize generation of reactive oxygen species (ROS) by equine spermatozoa.
SAMPLE POPULATION
Multiple semen samples collected from 9 stallions.
PROCEDURE
Equine spermatozoa were separated from seminal plasma on a discontinuous polyvinylpyrrolidone (PVP)-coated silica gradient and resuspended in a ... | 10.2460/ajvr.2001.62.508 | 11,327,456 | D000818:Animals; D000001:Calcimycin; D002374:Catalase; D002499:Centrifugation, Density Gradient; D015925:Cryopreservation; D006736:Horses; D006861:Hydrogen Peroxide; D007476:Ionophores; D008297:Male; D008857:Microscopy, Interference; D009240:N-Formylmethionine Leucyl-Phenylalanine; D009249:NADP; D017382:Reactive Oxygen... | American journal of veterinary research | 2,001 | D007476:Ionophores; D017382:Reactive Oxygen Species; D013481:Superoxides; D000001:Calcimycin; D009249:NADP; D009240:N-Formylmethionine Leucyl-Phenylalanine; D006861:Hydrogen Peroxide; D002374:Catalase; D013755:Tetradecanoylphorbol Acetate |
Structural Stability, Transitions, and Interactions within SoxYZCD-Thiosulphate from Sulfurimonas denitrificans: An In Silico Molecular Outlook for Maintaining Environmental Sulphur Cycle. | Thiosulphate oxidation (an essential mechanism) serves to maintain the global sulphur cycle. Earlier experimental and computational studies dealt with environmental thiosulphate oxidation but none dealt with thiosulphate oxidation from deep ocean belts. Wet-laboratory experimental research shows that epsilon-proteobact... | 10.1155/2016/8683713 | 27,777,586 | Journal of biophysics (Hindawi Publishing Corporation : Online) | 2,016 | ||
[Operation on the saddle nose]. | Most of the saddle deformities are due to trauma; less frequently, they may be a racial characteristic and in rare cases they follow chronic specific inflammatory diseases. The author considers the alternatives for surgical correction: 1. The small saddle requiring no graft 2. the saddle requiring little graft for whic... | 6,865,614 | D005260:Female; D006801:Humans; D008297:Male; D019736:Prostheses and Implants; D012225:Rhinoplasty | Laryngologie, Rhinologie, Otologie | 1,983 | ||
Respiratory movement and pain thresholds in airway environmental sensitivity, asthma and COPD. | INTRODUCTION
Patients with "sensory hyperreactivity" (SHR) have airway environmental sensitivity, chronic cough and dyspnoea. Cough, chest discomfort and sense of difficulties getting air are some of the symptoms these patients seek medical attendance for. The patients have increased cough sensitivity to inhaled capsai... | 10.1016/j.rmed.2012.03.011 | 22,510,540 | D001249:Asthma; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009068:Movement; D059352:Musculoskeletal Pain; D017288:Pain Threshold; D029424:Pulmonary Disease, Chronic Obstructive; D012130:Respiratory Hypersensitivity; D015656:Respiratory Mechanics; D013909:Thorax | Respiratory medicine | 2,012 | |
Application of microwave heating for the fast extraction of fat content from the poultry feeds. | A rapid method has been developed to extract and quantitatively measure the total oil content in poultry feeds using a domestic microwave oven. The optimized extraction procedure involves the replicate (6x) extraction of 5 g of ground feed with 12 ml of hexane for 20 s in a 900 W oven. Each replicate involves the colle... | 10.1016/j.talanta.2008.01.042 | 18,585,208 | D000821:Animal Feed; D000818:Animals; D002623:Chemistry Techniques, Analytical; D005230:Fatty Acids, Nonesterified; D006361:Heating; D008872:Microwaves; D011200:Poultry; D012997:Solvents; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors | Talanta | 2,008 | D005230:Fatty Acids, Nonesterified; D012997:Solvents |
Preformed and newly synthesized messenger RNA in germinating wheat embryos. | In 6 h germinated wheat (Triticum aestivum L. cv. Cama) embryos, more than half of the messenger RNAs are actively involved in translation. Neither preformed nor newly synthesized poly A(+)-RNA is translated preferentially. Germination in the presence of cordycepin showed that the half-life of the templates is about 2 ... | 10.1007/BF00380128 | 24,407,396 | Planta | 1,979 | ||
Precooling and ozone treatments affects postharvest quality of black mulberry (Morus nigra) fruits. | Mulberry (Morus spp.) fruits are delicious and nutritious, but they are highly perishable and have a very short shelf-life for sale in the market. This study investigated the effect and mechanisms of 2ppm ozone and precooling treatments on the postharvest quality of mulberry fruit during refrigerated storage. The resul... | 10.1016/j.foodchem.2016.11.152 | 27,979,184 | D003080:Cold Temperature; D003116:Color; D005511:Food Handling; D005638:Fruit; D031625:Morus; D010126:Ozone; D010936:Plant Extracts | Food chemistry | 2,017 | D010936:Plant Extracts; D010126:Ozone |
Multitiered and Cooperative Surveillance of Mitochondrial Phosphatidylserine Decarboxylase 1. | Phosphatidylserine decarboxylase 1 (Psd1p), an ancient enzyme that converts phosphatidylserine to phosphatidylethanolamine in the inner mitochondrial membrane, must undergo an autocatalytic self-processing event to gain activity. Autocatalysis severs the protein into a large membrane-anchored β subunit that noncovalent... | 10.1128/MCB.00049-17 | 28,606,933 | D002262:Carboxy-Lyases; D008928:Mitochondria; D051336:Mitochondrial Membranes; D024101:Mitochondrial Proteins; D010714:Phosphatidylethanolamines; D010718:Phosphatidylserines; D012441:Saccharomyces cerevisiae | Molecular and cellular biology | 2,017 | D024101:Mitochondrial Proteins; D010714:Phosphatidylethanolamines; D010718:Phosphatidylserines; C483858:phosphatidylethanolamine; D002262:Carboxy-Lyases; C022353:phosphatidylserine decarboxylase |
High-Amylose Starches to Bridge the "Fiber Gap": Development, Structure, and Nutritional Functionality. | Although high-amylose starches are not a recent innovation, their popularity in recent years has been increasing due to their unique functional properties and enhanced nutritional values in food applications. While high-amylose maize, barley, and potato are commercially available, high-amylose variants of other main cr... | 10.1111/1541-4337.12416 | 33,336,945 | Comprehensive reviews in food science and food safety | 2,019 | ||
Regulatory mechanisms of cutaneous delayed-type hypersensitivity. II. Suppression of cutaneous delayed-type hypersensitivity by macrophage disappearance reaction. | Studies were performed on the behavior of cutaneous delayed-type hypersensitivity (DTH) in guinea pigs in which macrophage disappearance reaction (MDR) was induced. Guinea pigs were immunized with dinitrophenylated egg albumin (DNP-EA), followed by intraperitoneal (ip) injection of liquid paraffin in order to elicit pe... | 10.1016/0008-8749(83)90219-8 | 6,352,056 | D000818:Animals; D000941:Antigens; D002478:Cells, Cultured; D005260:Female; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular; D007114:Immunization; D007700:Kinetics; D008222:Lymphokines; D008263:Macrophage Migration-Inhibitory Factors; D008264:Macrophages; D010835:Phytohemagglutinins | Cellular immunology | 1,983 | D000941:Antigens; D008222:Lymphokines; D008263:Macrophage Migration-Inhibitory Factors; D010835:Phytohemagglutinins |
Notch activity influences the alphabeta versus gammadelta T cell lineage decision. | The choice between the alphabeta or gammadelta T cell fates is influenced by the production of functional, in-frame rearrangements of the TCR genes, but the mechanism that controls the lineage choice is not known. Here, we show that T cells that are heterozygous for a mutation of the Notch1 gene are more likely to deve... | 10.1016/s0092-8674(00)81929-7 | 9,118,226 | D000818:Animals; D015496:CD4-Positive T-Lymphocytes; D018414:CD8-Positive T-Lymphocytes; D002454:Cell Differentiation; D019070:Cell Lineage; D005260:Female; D005434:Flow Cytometry; D018628:Gene Dosage; D015321:Gene Rearrangement; D006412:Hematopoietic Stem Cells; D006579:Heterozygote; D008297:Male; D008565:Membrane Pro... | Cell | 1,997 | D008565:Membrane Proteins; D016693:Receptors, Antigen, T-Cell, alpha-beta; D016692:Receptors, Antigen, T-Cell, gamma-delta; D051880:Receptors, Notch; D011993:Recombinant Fusion Proteins |
Leadership research in business and health care. | PURPOSE
To summarize research on leadership in the health care and business literature and to identify the outcomes of leadership on individuals, groups, and organizations.
METHODS
A computerized search and review of research studies was conducted in the health care and business literature from 1970-1999. Studies wer... | 10.1111/j.1547-5069.2002.00165.x | 12,078,542 | D003132:Commerce; D006296:Health Services; D006801:Humans; D007857:Leadership; D012106:Research; D000078329:Workforce | Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing | 2,002 | |
Depressive Symptoms among Plastic Surgery Residents. | BACKGROUND
A literature review did not reveal any study investigating the prevalence of depression among plastic surgery residents.
METHODS
We conducted a cross-sectional mail survey and included all Saudi Plastic Surgery residents in our local program in Saudi Arabia. The Beck Depression Inventory II was used.
RES... | 10.1097/GOX.0000000000001516 | 29,184,732 | Plastic and reconstructive surgery. Global open | 2,017 | ||
Intrathecal bradykinin acts presynaptically on spinal noradrenergic terminals to produce antinociception in the rat. | In the awake restrained rat the intrathecal (i.th.) administration of 8.1 pmol-8.1 nmol of bradykinin (BK) and kallidin (KD) enhanced the reaction time (RT) to a noxious radiant heat stimulus in a dose-dependent manner. The fragments BK-(1-8) and BK-(1-7) were active only at doses higher than 10 nmol and the following ... | 10.1016/0014-2999(89)90158-1 | 2,563,974 | D000317:Adrenergic alpha-Antagonists; D000700:Analgesics; D000818:Animals; D015306:Biogenic Monoamines; D001920:Bradykinin; D002395:Catecholamines; D002408:Catheters, Indwelling; D004146:Dioxanes; D004723:Endorphins; D006892:Hydroxydopamines; D019329:Idazoxan; D007278:Injections, Spinal; D007609:Kallidin; D008297:Male;... | European journal of pharmacology | 1,989 | D000317:Adrenergic alpha-Antagonists; D000700:Analgesics; D015306:Biogenic Monoamines; D002395:Catecholamines; D004146:Dioxanes; D004723:Endorphins; D006892:Hydroxydopamines; D015016:Yohimbine; D007609:Kallidin; D009270:Naloxone; D016627:Oxidopamine; D011433:Propranolol; D001920:Bradykinin; D011224:Prazosin; D019329:Id... |
How are tumour antigens related to normal antigens? | Tumour cells share with normal cells antigens characteristic of defined states of differentiation. Is there anything else? An example of tumour antigens not expressed anywhere in normal tissue is the set of tumour-specific transplantation antigens (TSTA) of murine chemically induced sarcomas. There is evidence that at ... | 10.1002/9780470720776.ch6 | 6,343,008 | D000818:Animals; D000941:Antigens; D000951:Antigens, Neoplasm; D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental | Ciba Foundation symposium | 1,983 | D000941:Antigens; D000951:Antigens, Neoplasm |
[Hepatitis B virus and hepatocellular carcinoma]. | Hepatocellular carcinoma in woodchuck were characterized for woodchuck hepatitis virus integration nea c-myc oncogene. In one tumor, viral integration resulted in overexpression of a c-myc viral cotranscript. In a second tumor, viral insertion, 600 bp upstream of c-myc exon 1, was associated with increased levels of no... | 1,772,242 | D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015870:Gene Expression; D016259:Genes, myc; D006515:Hepatitis B virus; D008113:Liver Neoplasms; D008114:Liver Neoplasms, Experimental; D008392:Marmota; D008969:Molecular Sequence Data; D000090063:Proto-Oncogene Mas; D012367:RNA, Viral; D012689:Sequen... | Annales de gastroenterologie et d'hepatologie | 1,991 | C000715470:MAS1 protein, human; D000090063:Proto-Oncogene Mas; D012367:RNA, Viral | |
[His electrogram recordings in disturbances of atrio-ventricular conduction in acute ryocardial infarction (author's transl)]. | 48 His bundle recordings were performed on 30 patients with acute mycardial infarction and various degrees of atrioventricular block. Studies were undertaken at the time of transvenous pacemaker insertion and/or removal from the right ventricle, without pharmacological or electrical stimulation tests. The connections b... | 1,222,888 | D000208:Acute Disease; D000368:Aged; D002036:Bundle of His; D004562:Electrocardiography; D005260:Female; D006327:Heart Block; D006329:Heart Conduction System; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction | Giornale italiano di cardiologia | 1,975 | ||
Shape and dynamics of thermoregulating honey bee clusters. | A model of simple algorithmic "agents" acting in a discrete temperature field is used to investigate the movement of individuals in thermoregulating honey bee (Apis mellifera) clusters. Thermoregulation in over-wintering clusters is thought to be the result of individual bees attempting to regulate their own body tempe... | 10.1006/jtbi.1999.1063 | 10,772,844 | D000465:Algorithms; D000818:Animals; D001516:Bees; D001522:Behavior, Animal; D001833:Body Temperature Regulation; D003198:Computer Simulation; D008954:Models, Biological; D013696:Temperature | Journal of theoretical biology | 2,000 | |
Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-β pathway. | miR122 is the prevalent miRNA in adult healthy liver and it is responsible for liver stem cell differentiation towards hepatocyte lineage. Its expression is frequently lost in hepatocellular carcinoma (HCC). We studied the effects of restoring miR122 expression in a distinctive cell line derived from human HCC-BCLC9 ce... | 10.18632/oncotarget.11885 | 27,612,430 | D000818:Animals; D006528:Carcinoma, Hepatocellular; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D018450:Disease Progression; D006801:Humans; D000090062:Kruppel-Like Factor 4; D008113:Liver Neoplasms; D051379:Mice; D035683:MicroRNAs; D014411:Neoplastic Stem Cells; D051057:Proto-Oncogene Proteins c-akt; D015398... | Oncotarget | 2,016 | C000715467:KLF4 protein, human; C000715468:Klf4 protein, mouse; D000090062:Kruppel-Like Factor 4; C531907:MIRN122 microRNA, human; D035683:MicroRNAs; D051785:Smad Proteins; D016212:Transforming Growth Factor beta; D051057:Proto-Oncogene Proteins c-akt |
Optimizing Lumbar Pedicle Screw Trajectory Utilizing a 3D-Printed Drill Guide to Ensure Placement of Pedicle Screws Into Higher Density Bone May Improve Pedicle Screw Pullout Resistance. | BACKGROUND
Lower preoperative Hounsfield Unit (HU) values of vertebral body are associated with pedicle screw (PS) loosening after implantation with traditional trans-pedicular trajectory. However, the relationship between trajectory HU value and PS fixation quality remains unknown. This study aimed to investigate if 3... | 10.1016/j.wneu.2021.11.002 | 34,763,101 | D001696:Biomechanical Phenomena; D015519:Bone Density; D001842:Bone and Bones; D006801:Humans; D008159:Lumbar Vertebrae; D008161:Lumbosacral Region; D065289:Pedicle Screws; D066330:Printing, Three-Dimensional; D013123:Spinal Fusion | World neurosurgery | 2,022 | |
Should all women with cervical atypia be referred for colposcopy: a HARNET study. Harrisburgh Area Research Network. | BACKGROUND
Clinicians who manage women with Papanicolaou (Pap) smears showing atypical squamous cells of undetermined significance (ASCUS) may miss clinically significant cervical disease by repeating the cytology alone. We evaluated the ability of the human papillomavirus (HPV) screen and the naked-eye examination aft... | 8,163,964 | D000085:Acetates; D019342:Acetic Acid; D000293:Adolescent; D000328:Adult; D003127:Colposcopy; D003218:Condylomata Acuminata; D005188:False Negative Reactions; D005194:Family Practice; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D065006:Papanicolaou Test; D027383:Papillomaviridae; D01... | The Journal of family practice | 1,994 | D000085:Acetates; D019342:Acetic Acid | |
Diagnosis and management of patients with Bell's palsy. | Bell's palsy (idiopathic facial paralysis) is the most common cause of acute unilateral facial nerve paralysis. Although it is usually a self-limiting condition, it can be distressing for the patient. Many people who experience one-sided facial paralysis fear that it is a symptom of stroke. However, there are subtle di... | 10.7748/ns2013.12.28.14.44.e7979 | 24,299,386 | D015670:Acupuncture Therapy; D000893:Anti-Inflammatory Agents; D000998:Antiviral Agents; D020330:Bell Palsy; D003937:Diagnosis, Differential; D006801:Humans; D011239:Prednisolone; D012720:Severity of Illness Index | Nursing standard (Royal College of Nursing (Great Britain) : 1987) | 2,013 | D000893:Anti-Inflammatory Agents; D000998:Antiviral Agents; D011239:Prednisolone |
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