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Dengue Vector Control through Community Empowerment: Lessons Learned from a Community-Based Study in Yogyakarta, Indonesia. | Effort to control dengue transmission requires community participation to ensure its sustainability. We carried out a knowledge attitude and practice (KAP) survey of dengue prevention to inform the design of a vector control intervention. A cross-sectional survey was conducted in June⁻August 2014 among 521 households i... | 10.3390/ijerph16061013 | 30,897,770 | D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000818:Animals; D003256:Community Participation; D003430:Cross-Sectional Studies; D003715:Dengue; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007214:Indonesia; D008297:Male; D008875:Middle Aged; D009032:Mosquito Control; D00007... | International journal of environmental research and public health | 2,019 | |
Anatomic localization of 24- and 96-h particle retention in canine airways. | Long-term retention of particles in airways is controversial. However, precise anatomic localization of the particles is not possible in people. In this study the anatomic location of retained particles after shallow bolus inhalation was determined in anesthetized, ventilated beagle dogs. Fifty 30-cm(3) boluses contain... | 10.1152/jappl.1999.87.1.269 | 10,409,585 | D000336:Aerosols; D000818:Animals; D004285:Dogs; D005260:Female; D006801:Humans; D008168:Lung; D008297:Male; D010316:Particle Size; D011650:Pulmonary Alveoli; D015656:Respiratory Mechanics; D013667:Technetium; D013997:Time Factors; D015899:Tomography, Emission-Computed, Single-Photon | Journal of applied physiology (Bethesda, Md. : 1985) | 1,999 | D000336:Aerosols; D013667:Technetium |
Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia. | Hereditary spastic paraplegias (HSPs) are a group of inherited, progressive neurodegenerative conditions characterised by prominent lower-limb spasticity and weakness, caused by a length-dependent degeneration of the longest corticospinal upper motor neurons. While more than 80 spastic paraplegia genes (SPGs) have been... | 10.1186/s40478-022-01343-6 | 35,346,366 | D000818:Animals; D004195:Disease Models, Animal; D004330:Drosophila; D004721:Endoplasmic Reticulum; D006801:Humans; D000071518:Liver X Receptors; D026901:Membrane Transport Proteins; D015419:Spastic Paraplegia, Hereditary | Acta neuropathologica communications | 2,022 | D000071518:Liver X Receptors; D026901:Membrane Transport Proteins |
Predicting Dihydropyrimidine Dehydrogenase Deficiency and Related 5-Fluorouracil Toxicity: Opportunities and Challenges of DPYD Exon Sequencing and the Role of Phenotyping Assays. | Deficiency of dihydropyrimidine dehydrogenase (DPD), encoded by the DPYD gene, is associated with severe toxicity induced by the anti-cancer drug 5-Fluorouracil (5-FU). DPYD genotyping of four recommended polymorphisms is widely used to predict toxicity, yet their prediction power is limited. Increasing availability of... | 10.3390/ijms232213923 | 36,430,399 | D006801:Humans; D042943:Dihydrouracil Dehydrogenase (NADP); D054067:Dihydropyrimidine Dehydrogenase Deficiency; D005472:Fluorouracil; D005467:Floxuridine; D000964:Antimetabolites, Antineoplastic; D005091:Exons | International journal of molecular sciences | 2,022 | D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil; D005467:Floxuridine; D000964:Antimetabolites, Antineoplastic |
Genome-wide Analysis of Cotton MYB Transcription Factor and the Functional Validation of GhMYB in Response to Drought Stress. | MYB transcription factors play the important roles during abiotic stress responses in plant kingdom. However, little is understood about the accurately systematic analysis of MYB genes simultaneously in four cotton species, including G. hirsutum, G. barbadense, G. arboreum, and G. raimondii. Herein, the phylogenetic an... | 10.1093/pcp/pcad125 | 37,847,105 | Plant & cell physiology | 2,023 | ||
Explainable Machine Learning Predictions of Perceptual Sensitivity for Retinal Prostheses. | To provide appropriate levels of stimulation, retinal prostheses must be calibrated to an individual's perceptual thresholds ('system fitting'), despite thresholds varying drastically across subjects, across electrodes within a subject, and over time. Although previous work has identified electrode-retina distance and ... | 10.1101/2023.02.09.23285633 | 36,798,201 | medRxiv : the preprint server for health sciences | 2,023 | ||
Pre-treatment of synthetic elastomeric scaffolds by cardiac fibroblasts improves engineered heart tissue. | Native myocardium consists of several cell types, of which approximately one-third are myocytes and most of the nonmyocytes are fibroblasts. By analogy with monolayer culture in which fibroblasts were removed to prevent overgrowth, early attempts to engineer myocardium utilized cell populations enriched for cardiac myo... | 10.1002/jbm.a.31578 | 18,041,719 | D000818:Animals; D003651:Decanoates; D020724:Elastomers; D005347:Fibroblasts; D005990:Glycerol; D008855:Microscopy, Electron, Scanning; D009200:Myocardial Contraction; D009203:Myocardial Infarction; D032383:Myocytes, Cardiac; D011108:Polymers; D019919:Prosthesis Implantation; D051381:Rats; D017207:Rats, Sprague-Dawley;... | Journal of biomedical materials research. Part A | 2,008 | D003651:Decanoates; D020724:Elastomers; D011108:Polymers; C036925:elastomeric polymer; C469892:poly(glycerol-sebacate); D005990:Glycerol |
The chromosome constitution of 1000 human spermatozoa. | Chromosomal analysis of 1000 spermatozoa from 33 normal men was performed using in vitro fertilization of zona-free golden hamster eggs. The frequency of abnormal sperm complements was 8.5%: 5.2% were aneuploid and 3.3% had a structural chromosome abnormality. The frequencies of hyperhaploid (2.4%) and hypohaploid (2.7... | 10.1007/BF00274750 | 6,683,243 | D000328:Adult; D000818:Animals; D002869:Chromosome Aberrations; D006224:Cricetinae; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007621:Karyotyping; D008297:Male; D008647:Mesocricetus; D008875:Middle Aged; D011003:Ploidies; D013094:Spermatozoa; D014960:X Chromosome; D014998:Y Chromosome | Human genetics | 1,983 | |
The role of protein C as an inhibitor of blood clotting during extracorporeal circulation. | The plasma levels of protein C, AT III, the perioperative administration of fresh frozen plasma (FFP) and AT III concentrate were compared under the use of various drugs in a randomized, prospective double-blind study in 40 patients in whom an aortocoronary bypass operation was carried out. We formed four groups of ten... | 10.1055/s-2007-1019995 | 1,724,102 | D000368:Aged; D000990:Antithrombin III; D007611:Aprotinin; D001026:Coronary Artery Bypass; D004311:Double-Blind Method; D011464:Epoprostenol; D005112:Extracorporeal Circulation; D006488:Hemostasis, Surgical; D006801:Humans; D008875:Middle Aged; D010949:Plasma; D011486:Protein C | The Thoracic and cardiovascular surgeon | 1,991 | D011486:Protein C; D000990:Antithrombin III; D007611:Aprotinin; D011464:Epoprostenol |
Scoring functions for protein-protein interactions. | The computational evaluation of protein-protein interactions will play an important role in organising the wealth of data being generated by high-throughput initiatives. Here we discuss future applications, report recent developments and identify areas requiring further investigation. Many functions have been developed... | 23,871,100 | D001185:Artificial Intelligence; D006801:Humans; D062105:Molecular Docking Simulation; D025941:Protein Interaction Mapping; D011506:Proteins | Current opinion in structural biology | 2,013 | D011506:Proteins | |
Protein kinase B (akt) promotes pathological angiogenesis in murine model of oxygen-induced retinopathy. | Akt, or protein kinase B, is an important signaling molecule that modulates many cellular processes such as cell growth, survival, and metabolism. However, the vivo roles and effectors of Akt in retinal angiogenesis are not explicitly clear. We therefore detected the expression of Akt using Western blotting or RT-PCR t... | 10.1267/ahc.10038 | 21,614,171 | Acta histochemica et cytochemica | 2,011 | ||
Avoidance of Vitamin K-Rich Foods Is Common among Warfarin Users and Translates into Lower Usual Vitamin K Intakes. | BACKGROUND
Warfarin users should aim for stable daily vitamin K intakes. However, some studies report that patients are often advised to avoid eating green vegetables. Whether this advice impacts vitamin K intakes is unknown.
OBJECTIVE
Our aim was to describe the nature and sources of vitamin K-related dietary recomm... | 26,922,378 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004032:Diet; D015930:Diet Records; D004034:Diet Surveys; D004435:Eating; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011792:Quebec; D064167:Recommended Dietary Allowances; D012189:Retrospective Studies; D014675:Ve... | Journal of the Academy of Nutrition and Dietetics | 2,016 | D014815:Vitamins; D014812:Vitamin K; D014859:Warfarin | |
Metabolic mechanisms of drug-nutrient interactions. | Metabolic mechanisms of nutrition and drug interactions include 1) the effects of diet on drug metabolism and action and 2) the effects of drugs on nutritional processes. The type, amount, and timing of foods consumed influence drug dissolution, absorption, distribution, metabolism, and excretion. High-fat meals enhanc... | 3,881,283 | D000042:Absorption; D000818:Animals; D001667:Binding, Competitive; D002648:Child; D004032:Diet; D004347:Drug Interactions; D004435:Eating; D005502:Food; D006801:Humans; D008658:Inactivation, Metabolic; D006899:Mixed Function Oxygenases; D009748:Nutrition Disorders; D009747:Nutritional Physiological Phenomena; D010084:O... | Federation proceedings | 1,985 | D004364:Pharmaceutical Preparations; D006899:Mixed Function Oxygenases | |
Light and electron microscopic examination of skeletal muscles in the reversed passive Arthus reaction. | The reversed passive Arthus reaction (RPAR) was performed in the dorsal area of the skin and skeletal muscles of the pelvic girdle of male guinea pigs. Biopsies were taken 3, 24 and 48 hours after antibody administration. In the dermal type of RPAR attention was paid to the structure of striated muscles of the subcutan... | 9,278,109 | D000818:Animals; D001183:Arthus Reaction; D006168:Guinea Pigs; D008297:Male; D008854:Microscopy, Electron; D018485:Muscle Fibers, Skeletal; D018482:Muscle, Skeletal; D012867:Skin | Polish journal of pathology : official journal of the Polish Society of Pathologists | 1,997 | ||
Gene expression profiling of human oocytes following in vivo or in vitro maturation. | BACKGROUND
Immature human oocytes matured in vitro, particularly those from gonadotrophin stimulated ovaries, are developmentally incompetent when compared with oocytes matured in vivo. This developmental incompetence has been explained as poor oocyte cytoplasmic maturation without any determination of the likely molec... | 10.1093/humrep/den085 | 18,346,995 | D005260:Female; D020869:Gene Expression Profiling; D015894:Genome, Human; D006801:Humans; D066298:In Vitro Techniques; D020411:Oligonucleotide Array Sequence Analysis; D009865:Oocytes; D013480:Superovulation | Human reproduction (Oxford, England) | 2,008 | |
Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol. | Previous study of self-organization of Taxol-stabilized microtubules into asters in Xenopus meiotic extracts revealed motor-dependent organizational mechanisms in the spindle. We revisit this approach using clarified cytosol with glycogen added back to supply energy and reducing equivalents. We added probes for NUMA an... | 10.1091/mbc.E12-12-0850 | 23,515,222 | D000818:Animals; D064107:Aurora Kinase B; D002474:Cell-Free System; D048749:Cytokinesis; D003600:Cytosol; D004398:Dyneins; D016547:Kinesins; D008540:Meiosis; D008870:Microtubules; D009865:Oocytes; D055550:Protein Stability; D008941:Spindle Apparatus; D059008:Time-Lapse Imaging; D029867:Xenopus Proteins; D014982:Xenopus... | Molecular biology of the cell | 2,013 | D029867:Xenopus Proteins; D064107:Aurora Kinase B; C576938:aurkb protein, Xenopus; D004398:Dyneins; D016547:Kinesins |
Recurrence of an inguinal hernia containing the dome of the bladder following laparoscopic repair with mesh: A case report. | INTRODUCTION
A sliding hernia is a rare type of inguinal hernia in which the hernia sac is partially formed by the wall of a viscus, such as the sigmoid colon, bladder, cecum, or appendix. Sliding hernias involving the bladder often present with obstructive urinary symptoms that could potential lead to serious complica... | 27,394,397 | International journal of surgery case reports | 2,016 | |||
Fate of lipid hydroperoxides in blood plasma. | Cholesteryl ester hydroperoxide (CE-OOH) and phosphatidylcholine hydroperoxide (PC-OOH) are the major primary oxidation products of lipoproteins. CE-OOH is present in human and rat plasmas while PC-OOH is undetectable. This is likely due to the enzymatic (plasma glutathione peroxidase) and the nonenzymatic (apolipoprot... | 10.1080/10715760000301311 | 11,237,101 | D000818:Animals; D002788:Cholesterol Esters; D006801:Humans; D008054:Lipid Peroxides; D007862:Phosphatidylcholine-Sterol O-Acyltransferase | Free radical research | 2,000 | D002788:Cholesterol Esters; D008054:Lipid Peroxides; C021976:cholesteryl linoleate; D007862:Phosphatidylcholine-Sterol O-Acyltransferase |
An investigation on the expression of miRNAs including miR-144 and miR-34a in plasma samples of RET-positive and RET-negative medullar thyroid carcinoma patients. | Medullary thyroid carcinoma (MTC) is a scarce cancerous disease, originating from parafollicular C cells of the thyroid gland. MTC can be manifested as an aggressive carcinoma with metastasis, especially in sporadic forms. Mutations of the rearranged during transfection (RET) proto-oncogene occurs in all hereditary and... | 10.1002/jcp.29055 | 31,297,834 | D000328:Adult; D014408:Biomarkers, Tumor; D018278:Carcinoma, Neuroendocrine; D005260:Female; D006801:Humans; D008297:Male; D035683:MicroRNAs; D009154:Mutation; D000090063:Proto-Oncogene Mas; D051096:Proto-Oncogene Proteins c-ret; D013964:Thyroid Neoplasms | Journal of cellular physiology | 2,020 | D014408:Biomarkers, Tumor; C000715470:MAS1 protein, human; C554293:MIRN144 microRNA, human; C522425:MIRN34 microRNA, human; D035683:MicroRNAs; D000090063:Proto-Oncogene Mas; D051096:Proto-Oncogene Proteins c-ret; C099282:RET protein, human |
Unique temperature profiles for the atmosphere below an observer from sunset images. | We were able to transform the usual refraction equations for an observer within a spherically symmetric atmosphere into an Abel integral equation that has a unique inverse. It is now possible to extract accurate temperature profiles of the atmosphere below an observer over the marine boundary layer with use of simple e... | 10.1364/ao.36.006957 | 18,259,567 | Applied optics | 1,997 | ||
Cervical thoracic duct cyst. | Thoracic duct cysts are rare lesions presenting as mediastinal or supraclavicular masses. We report a case of a 77-year-old female who presented with a left supraclavicular mass. A cervical thoracic duct cyst was suspected after contrast-enhanced computed tomography (CT) of the neck and chest. Diagnosis was confirmed b... | 10.1097/01.rti.0000148208.74252.84 | 15,818,210 | D000368:Aged; D001707:Biopsy, Needle; D003287:Contrast Media; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D008026:Ligation; D008220:Lymphography; D008476:Mediastinal Cyst; D009333:Neck; D013897:Thoracic Duct; D020775:Thoracic Surgery, Video-Assisted; D014057:Tomography, X-Ray Computed; D016896:Tr... | Journal of thoracic imaging | 2,005 | D003287:Contrast Media |
[Efectiveness and safety of switching to raltegravir-based regimen in dyslipidemic HIV-infected patients receiving antiretroviral therapy at Arriaran Foundation]. | BACKGROUND
The impact of switching antiretroviral therapy (ART) regimen for dyslipidemia management in HIV-infected (HIV+) patients has not been reported in Chile.
AIM
To assess effectiveness and safety at 12 months after switching to raltegravir-based regimen for dyslipidemia management.
METHODS
Retrospective coho... | 10.4067/S0716-10182019000400490 | 31,859,773 | D000328:Adult; D019380:Anti-HIV Agents; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D015331:Cohort Studies; D050171:Dyslipidemias; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections; D017320:HIV Protease Inhibitors; D006801:Humans; D008297:Male; D008875:Middle Aged; D0000... | Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia | 2,019 | D019380:Anti-HIV Agents; D017320:HIV Protease Inhibitors; D000068898:Raltegravir Potassium |
Comparison of antiemetic efficacy and safety of palonosetron vs ondansetron in the prevention of chemotherapy-induced nausea and vomiting in children. | BACKGROUND
Chemotherapy-induced nausea and vomiting (CINV) in children is a major side effect despite the use of combination antiemetic drugs.
OBJECTIVE
To compare the efficacy and safety profile of palonosetron, a second-generation 5-hydroxytryptamine-3 (5-HT3) receptor antagonist, with ondansetron in the prevention... | 10.12788/jcso.0139 | 26,270,519 | The Journal of community and supportive oncology | 2,015 | ||
Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome. | The effects of immunoglobulin G (IgG) from patients with the antiphospholipid syndrome (APS) upon monocyte activation have not been fully characterized. We carried out a comprehensive proteomic analysis of human monocytes treated with IgG from patients with different manifestations of the APS. Using 2-dimensional diffe... | 10.1182/blood-2014-05-577569 | 25,301,710 | D000328:Adult; D016736:Antiphospholipid Syndrome; D015153:Blotting, Western; D002478:Cells, Cultured; D002853:Chromatography, Liquid; D015180:Electrophoresis, Gel, Two-Dimensional; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D008297:Male; D008875:Middle Aged; D009000:Monocytes; D020543:Proteome; D040901:P... | Blood | 2,014 | D007074:Immunoglobulin G; D020543:Proteome |
Review: psychosocial well-being of parents and their children born after assisted reproduction. | OBJECTIVE
To critically review the empirical literature published from 1980 through June 2000 on the psychosocial well-being of parents and their children born after assisted reproduction.
METHODS
A computer-based literature search of PsycINFO and Medline was conducted. Empirical studies were reviewed to document the... | 10.1093/jpepsy/26.8.525 | 11,700,337 | D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010287:Parent-Child Relations; D016487:Parenting; D010553:Personality Development; D012099:Reproductive Techniques | Journal of pediatric psychology | 2,001 | |
[Pancreatic regeneration after major pancreatectomy and effect of insulin administration in dogs]. | Regeneration of the remnant pancreas after more than 92% pancreatectomy with or without insulin treatment was studied in dogs. All dogs developed diabetes mellitus (DM) immediately after surgery. For the dogs in insulin-treated group, porcine insulin (NPH) was injected subcutaneously daily to maintain the fasting blood... | 7,687,321 | D000818:Animals; D002455:Cell Division; D004247:DNA; D004285:Dogs; D007328:Insulin; D009955:Ornithine Decarboxylase; D010179:Pancreas; D010180:Pancreatectomy; D012313:RNA; D012038:Regeneration | Nihon Geka Gakkai zasshi | 1,993 | D007328:Insulin; D012313:RNA; D004247:DNA; D009955:Ornithine Decarboxylase | |
Uveal mast cells are not required for rodent uveitis. | Uveal mast cells have previously been considered to be vital mediators of experimental uveitis. We extended the study of these cells to experimental melanin-induced uveitis (EMIU), a recently described clinically relevant model, and re-examined their role in endotoxin-induced uveitis (EIU) using genetically mast cell-d... | 10.1159/000055500 | 9,731,121 | D000818:Animals; D002417:Cattle; D002452:Cell Count; D002829:Choroid; D005838:Genotype; D008070:Lipopolysaccharides; D008297:Male; D008407:Mast Cells; D008543:Melanins; D051379:Mice; D008811:Mice, Inbred DBA; D009154:Mutation; D051381:Rats; D011916:Rats, Inbred F344; D014602:Uvea; D014605:Uveitis | Ophthalmic research | 1,998 | D008070:Lipopolysaccharides; D008543:Melanins |
[Stimulation of ozone stress on the adhesion of inflammatory cells to bronchial epithelial cells]. | OBJECTIVE
To determine into the inflammation process of bronchial epithelial cells (BECs) and observe the modulatory effect of some protective factors on BECs.
METHODS
We built the cell injury model with ozone and observed the effect of ozone stress on polymorphonuclear loeukocyte (PMNs) and eosinophil (EOS) adhesion... | 12,575,287 | D000818:Animals; D001980:Bronchi; D002448:Cell Adhesion; D002478:Cells, Cultured; D004804:Eosinophils; D004847:Epithelial Cells; D005260:Female; D007249:Inflammation; D018799:Intercellular Adhesion Molecule-1; D008297:Male; D009504:Neutrophils; D010126:Ozone; D011817:Rabbits; D013312:Stress, Physiological | Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University | 2,002 | D018799:Intercellular Adhesion Molecule-1; D010126:Ozone | |
Isolated cysticercosis of tongue: a case report. | Cysticercosis of the tongue is a rare disease caused by infestation with the larval stage of the pork tapeworm (Taenia solium) in which man acts as a secondary host rather than a primary host. Most of these lesions are asymptomatic. The patient usually reports to the physician with the complaint of swelling. The solita... | 10.1002/dc.23109 | 24,610,792 | D044963:Biopsy, Fine-Needle; D002648:Child; D003551:Cysticercosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D014059:Tongue | Diagnostic cytopathology | 2,014 | |
Reflective practice: using the action learning group mechanism. | Many practising nurses, midwives, health visitors and their educators recognise the phenomena of the theory-practice gap. Due to social, economic and political developments it is now crucial for the gap to be closed. This paper provides a commentary on how one mechanism, called an action learning group (ALG), has been ... | 10.1016/s0260-6917(95)80075-1 | 7,708,025 | D004509:Education, Nursing, Continuing; D006126:Group Processes; D006801:Humans; D007858:Learning; D017145:Models, Educational; D013850:Thinking | Nurse education today | 1,995 | |
Tumor endothelial cells accelerate tumor metastasis. | Tumor metastasis is the main cause of cancer-related death. Understanding the molecular mechanisms underlying tumor metastasis is crucial to control this fatal disease. Several molecular pathways orchestrate the complex biological cell events during a metastatic cascade. It is now well known that bidirectional interact... | 10.1111/cas.13336 | 28,763,139 | D000818:Animals; D058578:Biglycan; D018450:Disease Progression; D042783:Endothelial Cells; D006801:Humans; D009362:Neoplasm Metastasis; D009369:Neoplasms; D009389:Neovascularization, Pathologic; D019899:Paracrine Communication; D015398:Signal Transduction; D059016:Tumor Microenvironment | Cancer science | 2,017 | C546884:BGN protein, human; D058578:Biglycan |
Bulk-darkening threshold of flux-grown KTiOPO(4). | A quantitative assessment of the bulk-darkening phenomenon for flux-grown KTiOPO(4) is reported. Measurements were made for KTiOPQ(4) use as a component for second-harmonic generation of 1064-nm Nd:YAG radiation operating in a pulsed mode. The results show that the bulk-darkening severity increases with fluence and exp... | 10.1364/ol.16.001307 | 19,776,953 | Optics letters | 1,991 | ||
Adherence to reporting guidelines increases the number of citations: the argument for including a methodologist in the editorial process and peer-review. | BACKGROUND
From 2005 to 2010, we conducted 2 randomized studies on a journal (Medicina Clínica), where we took manuscripts received for publication and randomly assigned them to either the standard editorial process or to additional processes. Both studies were based on the use of methodological reviewers and reporting... | 10.1186/s12874-019-0746-4 | 31,151,417 | D035081:Editorial Policies; D019983:Guideline Adherence; D006801:Humans; D055811:Journal Impact Factor; D010380:Peer Review; D011643:Publishing | BMC medical research methodology | 2,019 | |
Impact of Woven EndoBridge Shape Modification on Aneurysm Recanalization at Short-Term Follow-up Digital Subtraction Angiography. | BACKGROUND
Woven EndoBridge (WEB) shape modification (WSM) is a frequently observed phenomenon after aneurysm embolization.
OBJECTIVE
To test our hypothesis that WSM is associated with worse aneurysm occlusion on short-term angiographic follow-up images.
METHODS
Patients with short-term follow-up digital subtractio... | 10.1227/neu.0000000000001889 | 35,225,244 | D015901:Angiography, Digital Subtraction; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic; D057510:Endovascular Procedures; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm; D012189:Retrospective Studies; D016896:Treatment Outcome | Neurosurgery | 2,022 | |
Classical, Quantum and Event-by-Event Simulation of a Stern-Gerlach Experiment with Neutrons. | We present a comprehensive simulation study of the Newtonian and quantum model of a Stern-Gerlach experiment with cold neutrons. By solving Newton's equation of motion and the time-dependent Pauli equation for a wide range of uniform magnetic field strengths, we scrutinize the role of the latter for drawing the conclus... | 10.3390/e24081143 | 36,010,807 | Entropy (Basel, Switzerland) | 2,022 | ||
Use of Project ECHO to promote evidence based care for justice involved adults with opioid use disorder. | Background: People with opioid use disorders (OUDs) are at heightened risk for involvement with the criminal justice system. Growing evidence supports the safety and effectiveness of providing empirically supported treatments for OUD, such as medications for OUD (M-OUD), to people with criminal justice involvement incl... | 10.1080/08897077.2021.1941518 | 34,283,701 | D000328:Adult; D003416:Criminal Law; D003695:Delivery of Health Care; D019317:Evidence-Based Medicine; D006801:Humans; D058850:Opiate Substitution Treatment; D009293:Opioid-Related Disorders | Substance abuse | 2,022 | |
Mechanisms and implications of capillary endothelial swelling and luminal narrowing in low-flow ischemias. | Decreased functional capillary density (FCD) is a characteristic of low-flow ischemia which often persists on reperfusion of a tissue even though supply blood flow is reestablished. Capillary narrowing is a possible mechanism for the reduced blood reflow through an increase of the hydraulic resistance of the capillary ... | 10.1159/000179028 | 8,852,625 | D000818:Animals; D002196:Capillaries; D003198:Computer Simulation; D004730:Endothelium, Vascular; D007511:Ischemia; D008297:Male; D008833:Microcirculation; D018482:Muscle, Skeletal; D011817:Rabbits; D012039:Regional Blood Flow; D015427:Reperfusion Injury | International journal of microcirculation, clinical and experimental | 1,995 | |
Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence. | An abnormality in neurodevelopment is one of the most robust etiologic hypotheses in schizophrenia (SZ). There is also strong evidence that genetic factors may influence abnormal neurodevelopment in the disease. The present study evaluated in SZ patients, whose brain structural data had been obtained with magnetic reso... | 10.1016/j.psychres.2007.08.011 | 19,054,571 | D000328:Adult; D000483:Alleles; D001921:Brain; D015820:Cadherins; D015816:Cell Adhesion Molecules, Neuronal; D002540:Cerebral Cortex; D002552:Cerebral Ventricles; D004292:Dominance, Cerebral; D016326:Extracellular Matrix Proteins; D005260:Female; D005819:Genetic Markers; D005838:Genotype; D006801:Humans; D008279:Magnet... | Psychiatry research | 2,009 | D015820:Cadherins; D015816:Cell Adhesion Molecules, Neuronal; D016326:Extracellular Matrix Proteins; D005819:Genetic Markers; D009419:Nerve Tissue Proteins; C113432:PCDH12 protein, human; D000091363:Protocadherins; D000091042:Reelin Protein; C000717127:RELN protein, human; D012697:Serine Endopeptidases |
Aging effects on neural processing of rhythm and meter. | When listening to musical rhythm, humans can perceive and move to beat-like metrical pulses. Recently, it has been hypothesized that meter perception is related to brain activity responding to the acoustic fluctuation of the rhythmic input, with selective enhancement of the brain response elicited at meter-related freq... | 10.3389/fnagi.2022.848608 | 36,118,692 | Frontiers in aging neuroscience | 2,022 | ||
Isosorbide mononitrate versus alendronate for postmenopausal osteoporosis. | OBJECTIVE
To compare the effectiveness, safety, and affordability of isosorbide mononitrate with alendronate for postmenopausal osteoporosis.
METHODS
A randomized controlled trial of 60 postmenopausal women with osteoporosis. Participants were randomly assigned to receive either 20 mg daily of isosorbide mononitrate ... | 10.1016/j.ijgo.2008.07.011 | 18,805,524 | D015502:Absorptiometry, Photon; D019386:Alendronate; D015519:Bone Density; D050071:Bone Density Conservation Agents; D016001:Confidence Intervals; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007548:Isosorbide Dinitrate; D008875:Middle Aged; D020030:Nitric Oxide Donors; D015663:Osteoporosis, Postmeno... | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics | 2,008 | D050071:Bone Density Conservation Agents; D020030:Nitric Oxide Donors; D007548:Isosorbide Dinitrate; C030397:isosorbide-5-mononitrate; D019386:Alendronate |
Observations on the efficacy of intranasal beclomethasone dipropionate in cystic fibrosis patients. | The authors report the subjective results on the use of intranasal beclomethasone dipropionate in patients with cystic fibrosis. This medication has demonstrated positive results for these patients, whether polyps are present or not, and its use should be considered whenever symptoms of obstruction are present. | 3,343,722 | D000281:Administration, Intranasal; D000293:Adolescent; D001507:Beclomethasone; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis; D004341:Drug Evaluation; D006801:Humans; D009298:Nasal Polyps | The Journal of otolaryngology | 1,988 | D001507:Beclomethasone | |
A four year experience treating incomplete thoracolumbar spine injuries in an East African country. | Background
Traumatic spine injuries are one of the most common causes of disability and mortality.
Objective
To assess post op neurologic status in patients with incomplete thoracic and lumbar spine injuries at two teaching hospitals in Addis Ababa, Ethiopia.
Methods
Institution based retrospective cross-sectional ... | 10.1016/j.wnsx.2023.100175 | 37,151,992 | World neurosurgery: X | 2,023 | ||
Providing high-value, cost-conscious care: a critical seventh general competency for physicians. | There is general agreement that the U.S. economy cannot sustain the staggering economic burden imposed by the current and projected costs of health care. Whereas governmental approaches are focused primarily on decreasing spending for medical care, it is the responsibility of the medical profession to become cost-consc... | 10.7326/0003-4819-155-6-201109200-00007 | 21,930,856 | D002983:Clinical Competence; D003479:Curriculum; D004503:Education, Medical, Graduate; D017048:Health Care Costs; D006801:Humans; D007396:Internship and Residency | Annals of internal medicine | 2,011 | |
Effects of glucocorticoids on muscle protein turnover in perfused rat hemicorpus. | Normal and adrenalectomized rats treated with cortisone lost 2% of their initial body weight per day, whereas controls gained weight at a rate of 2%/day. Five days of treatment resulted in a 25% reduction in the weights of a number of mixed fiber type muscles, but did not affect the weights of heart or soleus, a muscle... | 10.1152/ajpendo.1980.238.6.E564 | 6,155,787 | D000596:Amino Acids; D000818:Animals; D002403:Cathepsins; D003348:Cortisone; D004247:DNA; D066298:In Vitro Techniques; D008297:Male; D009132:Muscles; D009206:Myocardium; D010442:Peptide Chain Initiation, Translational; D010477:Perfusion; D014176:Protein Biosynthesis; D011506:Proteins; D012313:RNA; D051381:Rats | The American journal of physiology | 1,980 | D000596:Amino Acids; D011506:Proteins; D012313:RNA; D004247:DNA; D002403:Cathepsins; D003348:Cortisone |
Use of recombinant C1 inhibitor in patients with resistant or frequent attacks of hereditary or acquired angioedema. | BACKGROUND
Conestat alfa (Ruconest, rhC1INH) is the first recombinant human C1 inhibitor protein (C1INH) for the treatment of acute attacks of hereditary angioedema (HAE).
OBJECTIVE
To assess clinical experience of the first 11 adult patients who received rhC1INH in clinical practice in the UK.
METHODS
Eleven patie... | 10.1684/ejd.2013.2252 | 24,556,385 | D000328:Adult; D000799:Angioedema; D054179:Angioedemas, Hereditary; D003174:Complement C1 Inactivator Proteins; D050718:Complement C1 Inhibitor Protein; D004351:Drug Resistance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins; D012008:Recurrence; D055815:Young Adult | European journal of dermatology : EJD | 2,014 | D003174:Complement C1 Inactivator Proteins; D050718:Complement C1 Inhibitor Protein; D011994:Recombinant Proteins; C469952:SERPING1 protein, human |
Efficacy and safety of beclomethasone dipropionate nasal aerosol in children with perennial allergic rhinitis. | BACKGROUND
Beclomethasone dipropionate (BDP) nasal aerosol (non-aqueous) is approved for management of seasonal and perennial allergic rhinitis (PAR) in adolescents and adults.
OBJECTIVE
To evaluate the efficacy and safety of BDP nasal aerosol at 80 μg/day in children with PAR.
METHODS
This 12-week, phase 3, double... | 26,115,578 | D000280:Administration, Inhalation; D018926:Anti-Allergic Agents; D001507:Beclomethasone; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D059085:Nasal Sprays; D011788:Quality of Life; D012221:Rhinitis, Allergic, P... | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology | 2,015 | D018926:Anti-Allergic Agents; D059085:Nasal Sprays; D001507:Beclomethasone | |
Recombinant Treponema pallidum protein Tp47 promotes the migration and adherence of THP-1 cells to human dermal vascular smooth muscle cells by inducing MCP-1 and ICAM-1 expression. | Vascular inflammation is a complex and multifactorial pathophysiological process that plays a crucial role in all stages of syphilis and is responsible for tissue damage. Little is known about the interactions of infiltrating immunocytes with human dermal vascular smooth muscle cells (HDVSMCs) in arterioles during the ... | 10.1016/j.yexcr.2019.04.035 | 31,075,255 | D002448:Cell Adhesion; D002465:Cell Movement; D002478:Cells, Cultured; D018932:Chemokine CCL2; D020405:Dermis; D006801:Humans; D018799:Intercellular Adhesion Molecule-1; D009131:Muscle, Smooth, Vascular; D016328:NF-kappa B; D010766:Phosphorylation; D051057:Proto-Oncogene Proteins c-akt; D011994:Recombinant Proteins; D0... | Experimental cell research | 2,019 | C111835:CCL2 protein, human; D018932:Chemokine CCL2; C573420:ICAM1 protein, human; D016328:NF-kappa B; D011994:Recombinant Proteins; D018799:Intercellular Adhesion Molecule-1; D051057:Proto-Oncogene Proteins c-akt; D048051:p38 Mitogen-Activated Protein Kinases; C485221:Tp47 protein, Treponema pallidum; D001618:beta-Lac... |
"The historical timeline of cranioplasty". | Cranioplasty, defined as the reconstruction of cranial defects, not only offers protective effects with an aesthetically pleasing outcome, but also reverses the altered physiology post craniotomy and craniectomy. The journey of cranioplasty from its roots to the neoteric armamentarium depicts how enormously the innovat... | 10.1016/j.bjps.2020.11.048 | 33,402,317 | D003399:Craniotomy; D006664:History; D006801:Humans; D062069:Inventions; D019651:Plastic Surgery Procedures; D012886:Skull; D013518:Surgery, Plastic | Journal of plastic, reconstructive & aesthetic surgery : JPRAS | 2,021 | |
Osteoprotegerin is associated with silent coronary artery disease in high-risk but asymptomatic type 2 diabetic patients. | OBJECTIVE
Osteoprotegerin (OPG) is an inhibitor of osteoclastogenesis, which has been recently involved in atherosclerosis. The relationship between coronary atherosclerosis and OPG has never been studied in asymptomatic type 2 diabetic patients.
RESEARCH DESIGN AND METHODS
This is a nested case-control study; 162 as... | 10.2337/diacare.28.9.2176 | 16,123,486 | D000318:Adrenergic beta-Agonists; D000368:Aged; D015415:Biomarkers; D003327:Coronary Disease; D003924:Diabetes Mellitus, Type 2; D003925:Diabetic Angiopathies; D004176:Dipyridamole; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006442:Glycated Hemoglobin; D006023:Glycoproteins; D006801:Humans; D0... | Diabetes care | 2,005 | D000318:Adrenergic beta-Agonists; D015415:Biomarkers; D006442:Glycated Hemoglobin A; D006023:Glycoproteins; D008055:Lipids; D053244:Osteoprotegerin; D010975:Platelet Aggregation Inhibitors; D018160:Receptors, Cytoplasmic and Nuclear; D018124:Receptors, Tumor Necrosis Factor; C506030:TNFRSF11B protein, human; D004176:Di... |
Using a conflict conceptual framework to describe challenges to coordinated patient care from the physicians' and pharmacists' perspective. | BACKGROUND
In an effort to increase cost-effectiveness of health care and reduce overall costs, patient-centered medical homes have been proposed to spur fundamental changes in the way primary care is delivered. One of the chief principles that describe a patient-centered medical home is that care is organized across a... | 10.1016/j.sapharm.2013.12.002 | 24,440,119 | D003220:Conflict, Psychological; D003299:Cooperative Behavior; D057286:Electronic Health Records; D006295:Health Resources; D006801:Humans; D007348:Insurance, Health; D007400:Interprofessional Relations; D007880:Legislation, Drug; D005791:Patient Care; D010595:Pharmacists; D010820:Physicians; D024382:Professional Role;... | Research in social & administrative pharmacy : RSAP | 2,014 | |
VO2 as a Highly Efficient Electrocatalyst for the Oxygen Evolution Reaction. | Herein, we report high electrocatalytic activity of monoclinic VO2 (M1 phase) for the oxygen evolution reaction (OER) for the first time. The single-phase VO2 (M1) nanoparticles are prepared in the form of uniformly covering the surface of individual carbon fibers constituting a carbon fiber paper (CFP). The VO2 nanopa... | 10.3390/nano12060939 | 35,335,752 | Nanomaterials (Basel, Switzerland) | 2,022 | ||
Retention in care and predictors of attrition among HIV-infected patients who started antiretroviral therapy in Kinshasa, DRC, before and after the implementation of the 'treat-all' strategy. | The retention of patients in care is a key pillar of the continuum of HIV care. It has been suggested that the implementation of a "treat-all" strategy may favor attrition (death or lost to follow-up, as opposed to retention), specifically in the subgroup of asymptomatic people living with HIV (PLWH) with high CD4 coun... | 10.1371/journal.pgph.0000259 | 36,962,315 | PLOS global public health | 2,022 | ||
Association of maternal weight gain in pregnancy with offspring obesity and metabolic and vascular traits in childhood. | BACKGROUND
We sought to examine the association of gestational weight gain (GWG) and prepregnancy weight with offspring adiposity and cardiovascular risk factors.
METHODS AND RESULTS
Data from 5154 (for adiposity and blood pressure) and 3457 (for blood assays) mother-offspring pairs from a UK prospective pregnancy co... | 10.1161/CIRCULATIONAHA.109.906081 | 20,516,377 | D002318:Cardiovascular Diseases; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008137:Longitudinal Studies; D008297:Male; D009765:Obesity; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011446:Prospective Studies; D012307:Risk Factors; D0154... | Circulation | 2,010 | |
Instability of the non-activated rotational thromboelastometry assay (NATEM) in citrate stored blood. | INTRODUCTION
The non-activated rotational thromboelastometric assay (NATEM) is increasingly used as sensitive test for the evaluation of the endogenous activation of haemostasis. The reproducibility of the test results in citrate stored blood has never been investigated.
MATERIALS AND METHODS
The NATEM assay was perf... | 26,044,665 | D000328:Adult; D000368:Aged; D016477:Artifacts; D001777:Blood Coagulation; D001793:Blood Preservation; D019343:Citric Acid; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013916:Thrombelastography | Thrombosis research | 2,015 | D019343:Citric Acid | |
Affordable and enjoyable health shopping: Commodified therapeutic landscapes for older people in China's urban open spaces. | The complex influences of the commodification of therapeutic landscapes on sense of health are not fully understood. This study investigates how commodification affects the healing sense of urban open spaces for older people from a relational approach. Drawing on eight months of fieldwork in two Chinese cities, it demo... | 10.1016/j.healthplace.2021.102621 | 34,243,058 | D000368:Aged; D000375:Aging; D002681:China; D002947:Cities; D003469:Culture; D005843:Geography; D006801:Humans | Health & place | 2,021 | |
Canadian guidelines for intravenous thrombolytic treatment in acute stroke. A consensus statement of the Canadian Stroke Consortium. | BACKGROUND
The thromobolytic drug, tissue plasminogen activator (tPA) has been approved in the United States for the treatment of acute ischemic stroke amid controversy and concern about the balance of risk and benefit. The Canadian Stroke Consortium (CSC), a national network of neurologists who collaborate on joint pr... | 10.1017/s0317167100034120 | 9,706,731 | D000208:Acute Disease; D002170:Canada; D002561:Cerebrovascular Disorders; D005343:Fibrinolytic Agents; D006801:Humans; D007275:Injections, Intravenous; D013300:Streptokinase; D010959:Tissue Plasminogen Activator | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques | 1,998 | D005343:Fibrinolytic Agents; D013300:Streptokinase; D010959:Tissue Plasminogen Activator |
Improved and selective platinum recovery from spent alpha-alumina supported catalysts using pretreated anionic ion exchange resin. | Improved and selective recovery of platinum from a spent dehydrogenation platinum alpha-alumina supported catalyst using a strong basic ion exchange resin is reported. Platinum and other precious metal group (PMG) complexes are leached using concentrated hydrochloric acid along with about 0.20 vol.% nitric acid as an o... | 10.1016/j.jhazmat.2005.09.044 | 16,260,084 | D000537:Aluminum Oxide; D002384:Catalysis; D002852:Chromatography, Ion Exchange; D006851:Hydrochloric Acid; D006900:Hydroxylation; D007475:Ion Exchange Resins; D010316:Particle Size; D010984:Platinum | Journal of hazardous materials | 2,006 | D007475:Ion Exchange Resins; D010984:Platinum; D000537:Aluminum Oxide; D006851:Hydrochloric Acid |
Evaluation of MRI issues for an access port with a radiofrequency identification (RFID) tag. | OBJECTIVE
A medical implant that contains metal, such as an RFID tag, must undergo proper MRI testing to ensure patient safety and to determine that the function of the RFID tag is not compromised by exposure to MRI conditions. Therefore, the objective of this investigation was to assess MRI issues for a new access por... | 23,684,963 | D002056:Burns; D000075202:Contraindications; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D008279:Magnetic Resonance Imaging; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D057233:Radio Frequency Identification Device; D018570:Risk Assessment; D062666:Vascular Access Devices | Magnetic resonance imaging | 2,013 | ||
Histological parameters for the quantitative assessment of muscular dystrophy in the mdx-mouse. | Duchenne muscular dystrophy is a severe X-linked hereditary disease caused by the absence of functional dystrophin. The dystrophin-deficient mdx-mouse strain is a widely used animal model for dystrophin-deficiency. Several therapeutic approaches for muscular dystrophy have been proposed by different laboratories. In or... | 10.1016/j.nmd.2004.06.008 | 15,351,425 | D000367:Age Factors; D000818:Animals; D004195:Disease Models, Animal; D006652:Histological Techniques; D007211:Indoles; D051379:Mice; D008810:Mice, Inbred C57BL; D018101:Mice, Inbred mdx; D018485:Muscle Fibers, Skeletal; D018482:Muscle, Skeletal; D009137:Muscular Dystrophy, Animal; D012016:Reference Values | Neuromuscular disorders : NMD | 2,004 | D007211:Indoles; C007293:DAPI |
An improved AdaBoost algorithm for identification of lung cancer based on electronic nose. | The research developed an improved intelligent enhancement learning algorithm based on AdaBoost, that can be applied for lung cancer breath detection by the electronic nose (eNose). First, collected the breath signals from volunteers by eNose, including healthy individuals and people who had lung cancer. Additionally, ... | 10.1016/j.heliyon.2023.e13633 | 36,915,521 | Heliyon | 2,023 | ||
[Medical treatment of early spontaneous miscarriages: a prospective study of outpatient management using misoprostol]. | OBJECTIVES
Medical treatment using misoprostol has been recommended as an alternative to surgical evacuation for spontaneous miscarriages in the first trimester, in order to avoid anesthesia, a surgical operation and hospitalization. Our aim was to assess the efficacy and the safety of vaginal misoprostol in out-patien... | 10.1016/s0368-2315(04)96547-7 | 15,480,279 | D000022:Abortion, Spontaneous; D000282:Administration, Intravaginal; D000553:Ambulatory Care; D015331:Cohort Studies; D005260:Female; D006801:Humans; D016595:Misoprostol; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011446:Prospective Studies; D016896:Treatment Outcome | Journal de gynecologie, obstetrique et biologie de la reproduction | 2,004 | D016595:Misoprostol |
Decay of Short-Term Motor Memory Regarding Force Reproduction. | This study investigated the process that contributes to the decay of short-term motor memory regarding force reproduction. Participants performed tonic flexion of the right index finger with the target force feedback (criterion phase) and reproduced this force level without feedback 3, 10, 30, or 60 s after the end of ... | 10.1123/mc.2022-0070 | 36,448,489 | D006801:Humans; D008570:Memory, Short-Term; D005385:Fingers; D005246:Feedback | Motor control | 2,023 | |
TEXT MY BP MEDS NOLA: A pilot study of text-messaging and social support to increase hypertension medication adherence. | Study objective
Non-Hispanic Black (NHB) adults have high hypertension (HTN) and cardiovascular disease (CVD) burden. Medication nonadherence limits control and self-measured blood pressure (SMBP) improves diagnosis and adherence. This predominantly NHB cohort pilot, via community-clinical linkages, with uncontrolled H... | 10.1016/j.ahjo.2023.100253 | 37,712,088 | American heart journal plus : cardiology research and practice | 2,023 | ||
Austrian Syndrome: Community-Acquired Pneumonia in an Unusual Triad. | Austrian syndrome corresponds to the triad of meningitis, pneumonia, and endocarditis caused by Streptococcus pneumoniae, there is no global or local incidence given the infrequency of entity. Scarce cases are published in Latin America, with none of them in Colombia. A case of Austrian syndrome by penicillin-resistant... | 10.5152/ThoracResPract.2023.22113 | 37,485,713 | Thoracic research and practice | 2,023 | ||
Environmental change, shifting distributions, and habitat conservation plans: A case study of the California gnatcatcher. | Many species have already experienced distributional shifts due to changing environmental conditions, and analyzing past shifts can help us to understand the influence of environmental stressors on a species as well as to analyze the effectiveness of conservation strategies. We aimed to (1) quantify regional habitat as... | 10.1002/ece3.3482 | 29,238,558 | Ecology and evolution | 2,017 | ||
Screening strategies and dynamic risk prediction models for Alzheimer's disease. | BACKGROUND
Characterizing the progression from Mild cognitive impairment (MCI) to Alzheimer's disease (AD) is essential for early AD prevention and targeted intervention. Our goal was to construct precise screening schemes for individuals with different risk of AD and to establish prognosis models for them.
METHODS
W... | 10.1016/j.jpsychires.2023.09.013 | 37,757,706 | D006801:Humans; D000544:Alzheimer Disease; D012189:Retrospective Studies; D053327:Apolipoprotein E4; D018450:Disease Progression; D011379:Prognosis; D060825:Cognitive Dysfunction | Journal of psychiatric research | 2,023 | D053327:Apolipoprotein E4 |
Formation of a freely suspended membrane via a combination of interfacial reaction and wetting. | Applying poly(ethoxysiloxane) (a liquid non-water-soluble polymer that can be hydrolyzed and cross-linked by diluted acids) to an air/pH 1 water interface gave rise to thin homogeneous solid layers. These layers were strong enough to be transferable to electron microscopy grids with holes of dimensions up to 150 microm... | 10.1021/la0509089 | 16,262,308 | Langmuir : the ACS journal of surfaces and colloids | 2,005 | ||
Tumour necrosis factor-alpha depletes histone deacetylase 1 protein through IKK2. | Class I histone deacetylases (HDACs) are ubiquitous enzymes that repress gene expression by deacetylating histone tails and promoting chromatin compaction. Pro-inflammatory agents activate programmes of gene expression through transcription factors such as nuclear factor-kappaB (NF-kappaB), even in the context of ubiqu... | 10.1038/sj.embor.7400613 | 16,374,504 | D000818:Animals; D051017:Apoptosis Regulatory Proteins; D002478:Cells, Cultured; D050759:Cyclin-Dependent Kinase Inhibitor p21; D005786:Gene Expression Regulation; D056284:Histone Deacetylase 1; D006655:Histone Deacetylases; D006801:Humans; D051550:I-kappa B Kinase; D007375:Interleukin-1; D008070:Lipopolysaccharides; D... | EMBO reports | 2,006 | D051017:Apoptosis Regulatory Proteins; C493956:CDKN1A protein, human; D050759:Cyclin-Dependent Kinase Inhibitor p21; D007375:Interleukin-1; D008070:Lipopolysaccharides; D008562:Membrane Glycoproteins; D034741:RNA, Small Interfering; D053221:TNF-Related Apoptosis-Inducing Ligand; C505653:TNFSF10 protein, human; C505654:... |
Biochemical and strain properties of CJD prions: complexity versus simplicity. | Prions, the agents responsible for transmissible spongiform encephalopathies, are infectious proteins consisting primarily of scrapie prion protein (PrP(Sc)), a misfolded, β-sheet enriched and aggregated form of the host-encoded cellular prion protein (PrP(C)). Their propagation is based on an autocatalytic PrP convers... | 10.1111/j.1471-4159.2011.07399.x | 21,790,605 | D000818:Animals; D002417:Cattle; D003062:Codon; D007562:Creutzfeldt-Jakob Syndrome; D058872:Epidemics; D014644:Genetic Variation; D006801:Humans; D018621:PrPC Proteins; D018620:PrPSc Proteins; D011328:Prions; D017433:Protein Structure, Secondary | Journal of neurochemistry | 2,011 | D003062:Codon; D018621:PrPC Proteins; D018620:PrPSc Proteins; D011328:Prions |
Maintenance of behavior by postponement of scheduled injections of nicotine in squirrel monkeys. | Responding by squirrel monkeys was maintained under a schedule of i.v. nicotine postponement. Each lever-pressing response postponed an impending i.v. injection for 60 sec; in the absence of responding, injections occurred very 20 sec. The lowest dose of nicotine (10 micrograms/kg/injection) maintained rates of respond... | 6,684,684 | D000818:Animals; D001522:Behavior, Animal; D001921:Brain; D004597:Electroshock; D006584:Hexamethonium Compounds; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008464:Mecamylamine; D009538:Nicotine; D011292:Premedication; D012453:Saimiri; D019966:Substance-Related Disorders | The Journal of pharmacology and experimental therapeutics | 1,983 | D006584:Hexamethonium Compounds; D008464:Mecamylamine; D009538:Nicotine | |
Voices. | In June I visited Londonderry/ Derry and Perth to hear from nurses and midwives about the issues that matter to them. | 10.7748/ns.25.47.26.s29 | 28,075,883 | Nursing standard (Royal College of Nursing (Great Britain) : 1987) | 2,011 | ||
Lactate infusion induces panic attacks in patients with premenstrual syndrome. | A sodium lactate test was performed during the premenstrual phase in 35 women suffering from prospectively confirmed premenstrual syndrome (PMS) and in 16 controls in order to assess whether these patients were sensitive to this test and whether this sensitivity was accounted for primarily by the presence of concomitan... | 10.1097/00006842-199205000-00005 | 1,620,805 | D000328:Adult; D001143:Arousal; D003431:Cross-Cultural Comparison; D005006:Ethnicity; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007558:Italy; D007773:Lactates; D008875:Middle Aged; D016584:Panic Disorder; D011293:Premenstrual Syndrome; D011569:Psychiatric Status Rating Scales; D012107:Research Design | Psychosomatic medicine | 1,992 | D007773:Lactates |
Rapid characterisation of archaeological midden components using FT-IR spectroscopy, SEM-EDX and micro-XRD. | Samples taken from middens at the Neolithic site of Catalhöyük in Turkey have been analysed using IR spectroscopy backed up by powder XRD and SEM-EDX. Microcomponents studied include fossil hackberries (providing evidence of ancient diet and seasonality), mineral nodules (providing evidence of post-depositional change)... | 10.1016/j.saa.2009.02.004 | 19,268,629 | D001106:Archaeology; D003296:Cooking; D005580:Fossils; D008903:Minerals; D013052:Spectrometry, X-Ray Emission; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors; D014421:Turkey; D034401:Ulmaceae; D014866:Waste Products; D014961:X-Ray Diffraction | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy | 2,009 | D008903:Minerals; D014866:Waste Products |
c-Myc induces changes in higher order rDNA structure on stimulation of quiescent cells. | c-Myc is an oncogenic transcription factor capable of activating transcription by all three nuclear RNA polymerases, thus acting as a high-level coordinator of protein synthesis capacity and cell growth rate. c-Myc recruits RNA polymerase I-related transcription factors to the rDNA when quiescent cells are stimulated t... | 10.1038/onc.2009.21 | 19,270,725 | D000818:Animals; D002460:Cell Line; D049109:Cell Proliferation; D004275:DNA, Ribosomal; D009687:Nuclear Proteins; D011401:Promoter Regions, Genetic; D016271:Proto-Oncogene Proteins c-myc; D012318:RNA Polymerase I; D051381:Rats; D035181:TATA-Box Binding Protein; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription... | Oncogene | 2,009 | D004275:DNA, Ribosomal; C000614416:Nkx2-1 protein, rat; D009687:Nuclear Proteins; D016271:Proto-Oncogene Proteins c-myc; D035181:TATA-Box Binding Protein; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors; D012318:RNA Polymerase I |
High expression of astrocyte elevated gene-1 is associated with clinical staging, metastasis, and unfavorable prognosis in gastric carcinoma. | More and more evidence has demonstrated that astrocyte elevated gene-1 (AEG-1) is tightly associated with progression, metastasis, and unfavorable prognosis in many malignancies. However, the potential biological role of AEG-1 in gastric carcinoma (GC) has not been thoroughly delineated. In the current study, we found ... | 10.1007/s13277-014-2827-7 | 25,407,490 | D014408:Biomarkers, Tumor; D015815:Cell Adhesion Molecules; D018450:Disease Progression; D005260:Female; D005753:Gastric Mucosa; D015870:Gene Expression; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008565:Membrane Proteins; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012333:RNA, ... | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine | 2,015 | D014408:Biomarkers, Tumor; D015815:Cell Adhesion Molecules; C483039:MTDH protein, human; D008565:Membrane Proteins; D012333:RNA, Messenger; D016601:RNA-Binding Proteins |
Immunologic abnormalities in sarcoidosis. | Patients with active sarcoidosis (acute and chronic) have a depression in systemic cell-mediated immunity manifested by a reduction in the number of circulating T cells and impaired responses of these cells to polyclonal mitogens and recall antigens. These abnormalities are absent in patients with resolved disease and ... | 10.7326/0003-4819-92-3-406 | 6,986,831 | D000917:Antibody Formation; D000936:Antigen-Antibody Complex; D001323:Autoantibodies; D001402:B-Lymphocytes; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins; D007156:Immunologic Memory; D007731:Kveim Test; D008171:Lung Diseases; D008213:Lymphocyte Activation; D009000:Monocytes; D011650:Pulmonary Alv... | Annals of internal medicine | 1,980 | D000936:Antigen-Antibody Complex; D001323:Autoantibodies; D007136:Immunoglobulins |
[Percutaneous cholecystostomy guided by ultrasonography. A preliminary experience]. | Surgical cholecystostomy is a palliative treatment for cholecystitis and distal biliary obstructions when the general condition of the patient does not allow complex techniques. Percutaneous cholecystostomy (PC) guided by ultrasonography is an alternative to that procedure as well as a method of direct access to the bi... | 2,223,250 | D000368:Aged; D000369:Aged, 80 and over; D002764:Cholecystitis; D002767:Cholecystostomy; D002779:Cholestasis; D005260:Female; D006801:Humans; D008875:Middle Aged; D014463:Ultrasonography | Revista espanola de enfermedades digestivas | 1,990 | ||
Beta-adrenergic receptors in human anterior optic nerve: an autoradiographic study. | Sections of human anterior optic nerve and nerve head were incubated in a physiological solution containing a radiolabelled beta blocker at a low concentration. The beta blocker used was (-)-(125iodo)-cyanopindolol, which has a high affinity and specificity for beta-adrenergic receptors. Concurrent incubations were per... | 10.1038/eye.1993.25 | 8,392,006 | D001345:Autoradiography; D006801:Humans; D020120:Iodocyanopindolol; D009898:Optic Disk; D009900:Optic Nerve; D010869:Pindolol; D011433:Propranolol; D011943:Receptors, Adrenergic, beta | Eye (London, England) | 1,993 | D011943:Receptors, Adrenergic, beta; D020120:Iodocyanopindolol; D011433:Propranolol; D010869:Pindolol |
Clinical variability in congenital fiber type disproportion. | Congenital Fiber Type Disproportion (CFTD) has recently been described as a consistent and stereotyped clinicopathological entity, including congenital nonprogressive hypotonia and weakness, contractures, kyphoscoliosis, high arched palate, dislocated hips, short stature, and feet deformities. Our personal experience w... | 10.1016/0022-510x(80)90050-7 | 7,381,515 | D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders; D006801:Humans; D007223:Infant; D008297:Male; D009123:Muscle Hypotonia; D009132:Muscles; D009468:Neuromuscular Diseases; D013577:Syndrome | Journal of the neurological sciences | 1,980 | |
Differentiating characteristics of myocardial nuclei in cardiomyopathy. | Myocardial tissue obtained by endomyocardial biopsy was semiquantitatively evaluated for nuclear and nucleolar characteristics in six groups of patients: patients with normal cardiac function (group 1), doxorubicin-induced cardiomyopathy (group 2), idiopathic cardiomyopathy (group 3), alcoholic cardiomyopathy (group 4)... | 10.1016/s0046-8177(83)80177-4 | 6,629,369 | D000704:Analysis of Variance; D009202:Cardiomyopathies; D002310:Cardiomyopathy, Alcoholic; D002466:Cell Nucleolus; D002467:Cell Nucleus; D003937:Diagnosis, Differential; D006333:Heart Failure; D006349:Heart Valve Diseases; D006801:Humans; D008854:Microscopy, Electron; D009206:Myocardium; D014777:Virus Diseases | Human pathology | 1,983 | |
Fine-scale comparative phylogeography of a sympatric sister species triplet of subterranean diving beetles from a single calcrete aquifer in Western Australia. | Calcrete aquifers in the arid Yilgarn region of central Western Australia are a biodiversity hotspot for stygofauna. A distinct pattern of interspecific size class variation among subterranean dytiscid beetle species has been observed in 29 of these aquifers where either two or three small, medium and/or large sympatri... | 10.1111/j.1365-294X.2009.04296.x | 19,674,311 | D000818:Animals; D044822:Biodiversity; D001517:Coleoptera; D004272:DNA, Mitochondrial; D019143:Evolution, Molecular; D049810:Genetic Speciation; D014644:Genetic Variation; D005828:Genetics, Population; D005843:Geography; D006239:Haplotypes; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D014904:Western Australia | Molecular ecology | 2,009 | D004272:DNA, Mitochondrial |
[Patient blood management (part 2). Practice: the 3 pillars]. | Patient blood management (PBM) is a patient-specific multidisciplinary, multimodal, evidence-based concept to appropriately conserve and manage a patient's own blood as a vital resource. PBM is based on 3 pillars: the first is the optimization of the patient's endogenous red cell mass, the second is the minimization of... | 10.1055/s-0031-1284465 | 21,815,114 | D000740:Anemia; D001317:Austria; D019985:Benchmarking; D001803:Blood Transfusion; D017707:Erythrocyte Transfusion; D004911:Erythrocyte Volume; D004921:Erythropoietin; D006402:Hematologic Diseases; D006801:Humans; D007430:Intraoperative Care; D057725:Operative Blood Salvage; D010346:Patient Care Management; D019990:Peri... | Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS | 2,011 | D010952:Plasma Substitutes; D004921:Erythropoietin |
Postnatal changes in epigenetic modifications of neutrophils of foals are associated with increased ROS function and regulation of neutrophil function. | Neonates of all species, including foals, are highly susceptible to infection, and neutrophils play a crucial role in innate immunity to infection. Evidence exists that neutrophils of neonatal foals are functionally deficient during the first weeks of life, including expression of cytokine genes such as IFNG. We hypoth... | 10.1016/j.dci.2018.06.012 | 29,958,850 | D000818:Animals; D000831:Animals, Newborn; D016207:Cytokines; D044127:Epigenesis, Genetic; D006657:Histones; D006734:Horse Diseases; D006736:Horses; D007113:Immunity, Innate; D008239:Lysine; D008745:Methylation; D009504:Neutrophils; D011401:Promoter Regions, Genetic; D017382:Reactive Oxygen Species; D015398:Signal Tran... | Developmental and comparative immunology | 2,018 | D016207:Cytokines; D006657:Histones; D017382:Reactive Oxygen Species; D008239:Lysine |
Carbon nano-onions as potential nanocarriers for drug delivery. | Nanocarriers are nano-sized delivery vesicles that can transport desired molecules to a specific location. The utilisation of nanocarriers for targeted drug-delivery is an emerging field that aims to solve certain disadvantages of free drug delivery; including premature drug degradation, non-specific toxicity, lack of ... | 10.1039/d0dt04093b | 33,471,000 | D000818:Animals; D002244:Carbon; D016503:Drug Delivery Systems; D006801:Humans; D049329:Nanostructures | Dalton transactions (Cambridge, England : 2003) | 2,021 | D002244:Carbon |
A HPLC validated assay of paclitaxel's related impurities in pharmaceutical forms containing Cremophor EL. | A HPLC method has been developed for the determination of the paclitaxel's related impurities in pharmaceutical forms. This method ensures the rapid determination of related impurities in the presence of polyoxyl castor oil--the main constituent of paclitaxel's clinical formulation vehicle. The method is simple and doe... | 10.1016/s0731-7085(03)00632-0 | 15,127,804 | D002851:Chromatography, High Pressure Liquid; D004340:Drug Contamination; D005990:Glycerol; D017239:Paclitaxel; D004364:Pharmaceutical Preparations | Journal of pharmaceutical and biomedical analysis | 2,004 | D004364:Pharmaceutical Preparations; C000515:cremophor EL; D017239:Paclitaxel; D005990:Glycerol |
Greater muscle damage induced by fast versus slow velocity eccentric exercise. | Debate exists concerning the effect of contraction velocity on muscle damage, and few human studies have yet to address this issue. This study examined whether the velocity of eccentric exercise affected the magnitude of muscle damage. Twelve untrained subjects performed a series of slow velocity isokinetic eccentric e... | 10.1055/s-2005-865920 | 16,874,584 | D000328:Adult; D001132:Arm; D003402:Creatine Kinase; D004551:Elbow Joint; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D009119:Muscle Contraction; D018763:Muscle Fatigue; D018482:Muscle, Skeletal; D016059:Range of Motion, Articular; D020127:Recovery of Function; D019415:Torque | International journal of sports medicine | 2,006 | D003402:Creatine Kinase |
Naphthoquinones and derivatives as potential anticancer agents: An updated review. | One of the leading global causes of death is cancer; even though several treatment methods have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones are a type of quinone that is found in nature and has vital biological roles. These chemicals have anticancer (antineoplastic), analgesic... | 10.1016/j.cbi.2022.110198 | 36,179,774 | D009285:Naphthoquinones; D000970:Antineoplastic Agents; D011809:Quinones; D010084:Oxidation-Reduction; D000962:Antimalarials | Chemico-biological interactions | 2,022 | D009285:Naphthoquinones; D000970:Antineoplastic Agents; D011809:Quinones; D000962:Antimalarials |
Quantum maximum entropy principle for fractional exclusion statistics. | Using the Wigner representation, compatibly with the uncertainty principle, we formulate a quantum maximum entropy principle for the fractional exclusion statistics. By considering anyonic systems satisfying fractional exclusion statistic, all the results available in the literature are generalized in terms of both the... | 10.1103/PhysRevLett.110.020404 | 23,383,879 | Physical review letters | 2,013 | ||
Posterior sternoclavicular dislocation: a case report. | Posterior sternoclavicular dislocation is a relatively rare form of trauma, but one that must be recognized by the emergency physician. Such a case is presented here. Due to the proximity of the clavicle to critical thoracic outlet structures, serious complications can arise from a posterior dislocation: impingement on... | 10.1016/0736-4679(94)90484-7 | 7,884,197 | D000293:Adolescent; D005538:Football; D006801:Humans; D004204:Joint Dislocations; D008297:Male; D008349:Manipulation, Orthopedic; D013247:Sternoclavicular Joint | The Journal of emergency medicine | 1,994 | |
Effectiveness of different treatment modalities for the management of adult-onset granulosa cell tumours of the ovary (primary and recurrent). | BACKGROUND
Granulosa cell tumour is a rare gynaecological tumour of the ovary with recurrences many years after initial diagnosis and treatment. Evidence-based management of granulosa cell tumour of the ovary is limited, and treatment has not been standardised. Surgery, including fertility-sparing procedures for young ... | 10.1002/14651858.CD006912.pub2 | 24,753,008 | D000328:Adult; D017024:Chemotherapy, Adjuvant; D005260:Female; D006106:Granulosa Cell Tumor; D006801:Humans; D008197:Lymph Node Excision; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local; D018365:Neoplasm, Residual; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies | The Cochrane database of systematic reviews | 2,014 | |
Effects of the COVID-19 pandemic and previous pandemics, epidemics and economic crises on mental health: systematic review. | BACKGROUND
A rise in mental illness is expected to follow the COVID-19 pandemic, which has also been projected to lead to a deep global economic recession, further adding to risk factors.
AIMS
The aim of this review was to assess the impact of the COVID-19 pandemic and previous pandemics, epidemics and economic crise... | 10.1192/bjo.2022.587 | 36,214,114 | BJPsych open | 2,022 | ||
Possible deletion of a developmentally regulated heavy-chain variable region gene in autoimmune diseases. | Several autoantibody-associated variable region (V) genes are preferentially expressed during early ontogenic development, suggesting strongly that they are of developmental and physiological importance. As such, it is possible that polymorphisms in one or more of these genes may alter susceptibility to autoimmune dise... | 10.1073/pnas.87.20.7907 | 2,122,448 | D001172:Arthritis, Rheumatoid; D001327:Autoimmune Diseases; D002872:Chromosome Deletion; D004247:DNA; D005803:Genes, Immunoglobulin; D015698:Genomic Library; D006801:Humans; D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region; D007962:Leukocytes; D008180:Lupus Erythematosus, Systemic; D012016:Re... | Proceedings of the National Academy of Sciences of the United States of America | 1,990 | D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region; D004247:DNA |
Photoinduced Hydrocarboxylation via Thiol-Catalyzed Delivery of Formate Across Activated Alkenes. | Herein we disclose a new photochemical process to prepare carboxylic acids from formate salts and alkenes. This redox-neutral hydrocarboxylation proceeds in high yields across diverse functionalized alkene substrates with excellent regioselectivity. This operationally simple procedure can be readily scaled in batch at ... | 10.1021/jacs.1c07562 | 34,380,308 | D000475:Alkenes; D002264:Carboxylic Acids; D005561:Formates; D015394:Molecular Structure; D055668:Photochemical Processes; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds | Journal of the American Chemical Society | 2,021 | D000475:Alkenes; D002264:Carboxylic Acids; D005561:Formates; D013438:Sulfhydryl Compounds |
A novel mutation in the MITF gene causes Waardenburg syndrome type 2. | Mutations in the MITF gene on human chromosome 3 have been reported in families with Waardenburg Syndrome Type 2 (WS2), an autosomal dominant disorder responsible for a large proportion of congenital hearing loss. We examined 16 families with WS2 for mutations in the MITF gene. In one four-generation family, we found a... | 10.1016/1050-3862(95)00148-4 | 8,880,147 | D001665:Binding Sites; D004252:DNA Mutational Analysis; D004268:DNA-Binding Proteins; D005260:Female; D006801:Humans; D008297:Male; D051739:Microphthalmia-Associated Transcription Factor; D009154:Mutation; D010375:Pedigree; D010641:Phenotype; D014157:Transcription Factors; D014849:Waardenburg Syndrome | Genetic analysis : biomolecular engineering | 1,996 | D004268:DNA-Binding Proteins; C497234:MITF protein, human; D051739:Microphthalmia-Associated Transcription Factor; D014157:Transcription Factors |
Selection and mapping of replication origins from a 500-kb region of the human X chromosome and their relationship to gene expression. | In higher eukaryotes the mechanism controlling initiation of DNA replication remains largely unknown. New technologies are needed to shed light on how DNA replication initiates along the genome in specific regions. To identify the human DNA sequence requirements for initiation of replication, we developed a new method ... | 10.1006/geno.1999.5985 | 10,585,763 | D015139:Blotting, Southern; D002874:Chromosome Mapping; D004261:DNA Replication; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D008214:Lymphocytes; D008297:Male; D008969:Molecular Sequence Data; D010835:Phytohemagglutinins; D016133:Polymerase Chain Reaction; D018741:Replication Origin; D017422:Seq... | Genomics | 1,999 | D010835:Phytohemagglutinins |
Ulex europaeus 1 lectin targets microspheres to mouse Peyer's patch M-cells in vivo. | The interaction of latex microspheres with mouse Peyer's patch membranous M-cells was studied in a mouse gut loop model after the microspheres were coated with a variety of agents. Carboxylated microspheres (diameter 0.5 micron) were covalently coated with lectins Ulex europaeus 1, Concanavalin A, Euonymus europaeus an... | 10.1016/s0264-410x(97)00222-3 | 9,491,509 | D000704:Analysis of Variance; D000818:Animals; D003208:Concanavalin A; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D007070:Immunoglobulin A; D037102:Lectins; D051379:Mice; D008807:Mice, Inbred BALB C; D008863:Microspheres; D010581:Peyer's Patches; D037121:Plant Lectins; D012710:Serum Albumin, Bovine | Vaccine | 1,998 | D007070:Immunoglobulin A; D037102:Lectins; D037121:Plant Lectins; C036850:Ulex europaeus lectins; D003208:Concanavalin A; D012710:Serum Albumin, Bovine |
Which computational mechanisms operate in the hippocampus during novelty detection? | A fundamental property of adaptive behavior is the ability to rapidly distinguish what is novel from what is familiar in our environment. Empirical evidence and computational work have provided biologically plausible models of the neural substrate and mechanisms underlying the coding of stimulus novelty in the perirhin... | 10.1002/hipo.20326 | 17,598,148 | D000818:Animals; D004192:Discrimination, Psychological; D001330:Electronic Data Processing; D005106:Exploratory Behavior; D006624:Hippocampus; D006801:Humans; D008954:Models, Biological; D010364:Pattern Recognition, Visual; D010775:Photic Stimulation | Hippocampus | 2,007 | |
Joint Indian Chest Society-National College of Chest Physicians (India) guidelines for spirometry. | Although a simple and useful pulmonary function test, spirometry remains underutilized in India. The Indian Chest Society and National College of Chest Physicians (India) jointly supported an expert group to provide recommendations for spirometry in India. Based on a scientific grading of available published evidence, ... | 10.4103/lungindia.lungindia_300_18 | 31,006,703 | Lung India : official organ of Indian Chest Society | 2,019 | ||
The physician as comforter. | Patients, their families and even physicians themselves have commented on the lack of communication skills, empathy and concern for the psychosocial aspect of patient care among doctors of today. The call by many in the medical community for a renewed commitment to professionalism is partially in response to these conc... | 10.1016/j.ejim.2004.11.005 | 15,833,674 | European journal of internal medicine | 2,005 | ||
Carpal tunnel syndrome and development of trigger digit. | Although the coexistence of carpal tunnel syndrome and trigger digit in the same hand is well documented, the interactive relationship between them is unclear. This study was conducted to examine the factors that may impact on the development of trigger digit in the hand with idiopathic carpal tunnel syndrome. One hund... | 10.1016/j.jocn.2004.08.005 | 15,639,409 | D000368:Aged; D002349:Carpal Tunnel Syndrome; D005260:Female; D005385:Fingers; D006801:Humans; D007592:Joint Diseases; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009069:Movement Disorders; D019635:Neurosurgical Procedures; D011446:Prospective Studies; D011859:Radiography | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia | 2,005 |
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