title large_stringlengths 0 979 | abstract large_stringlengths 1 94.7k | doi large_stringlengths 0 71 | pmid int64 21 38.1M | mesh_terms large_stringlengths 0 1.47k | journal large_stringlengths 1 239 | pubdate int16 1.97k 2.02k | chemical_list large_stringlengths 0 1.47k |
|---|---|---|---|---|---|---|---|
Establishing the role of the FES tyrosine kinase in the pathogenesis, pathophysiology, and severity of sepsis and its outcomes. | Introduction
Sepsis is a result of initial over-activation of the immune system in response to an infection or trauma that results in reduced blood flow and life-threatening end-organ damage, followed by suppression of the immune system that prevents proper clearance of the infection or trauma. Because of this, therapi... | 10.3389/fimmu.2023.1145826 | 37,122,758 | D000818:Animals; D051379:Mice; D011505:Protein-Tyrosine Kinases; D018805:Sepsis; D015398:Signal Transduction; D007107:Immune System; D065206:Extracellular Traps | Frontiers in immunology | 2,023 | D011505:Protein-Tyrosine Kinases |
Newer medications for complicated depression. | Available antidepressant medications are safe and moderately effective for most patients, but their overall efficacy is similar and underwhelming. The most recently developed antidepressants are either stereoisomers or metabolites of older drugs or belong to an existing class of antidepressants. The development of new ... | 10.4088/JCP.8001tx12c | 19,818,239 | D000928:Antidepressive Agents; D003866:Depressive Disorder; D015195:Drug Design; D055808:Drug Discovery; D006801:Humans; D016896:Treatment Outcome | The Journal of clinical psychiatry | 2,009 | D000928:Antidepressive Agents |
A structural model of well-being, spontaneity and self-efficacy: Italian validation between adolescents and young adults. | INTRODUCTION
The passage from adolescence to young adulthood introduces many challenges and chances aimed at promoting independence, financial self-sufficiency, assumption of responsibilities and separation from parents. Literature shows that in the continuum between these two phases of life, many factors intervene, pr... | 10.1590/2237-6089-2017-0072 | 29,995,158 | D000293:Adolescent; D000328:Adult; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D007175:Impulsive Behavior; D008297:Male; D008960:Models, Psychological; D010551:Personality; D011581:Psychological Tests; D000297:Psychology, Adolescent; D020377:Self Efficacy; D012737:Sex Factors; D013315:Stress, ... | Trends in psychiatry and psychotherapy | 2,018 | |
Brain-derived neurotrophic factor levels in perinatal depression: A systematic review and meta-analysis. | BACKGROUND
This systematic review and meta-analysis aim to synthesize the available evidence and determine the overall brain-derived neurotrophic factor (BDNF) levels in individuals diagnosed with perinatal depression (PND).
METHODS
We performed a thorough search of electronic databases, including PubMed, Embase, Psy... | 10.1111/acps.13632 | 37,974,390 | Acta psychiatrica Scandinavica | 2,023 | ||
Calculation of hydrodynamic mass for atomic impurities in helium. | We present a simple numerical procedure for calculating the irrotational hydrodynamic flow around a spherical solute in superfluid helium. The results for alkali cations are compared to recent many-body variational Monte Carlo (VMC) calculations. The helium contribution to the effective masses calculated by the VMC and... | 10.1103/PhysRevLett.88.145301 | 11,955,157 | Physical review letters | 2,002 | ||
Full genome characterization and phylogenetic analysis of hepatitis B virus in gibbons and a caretaker in Central Kalimantan, Indonesia. | Hepatitis B virus (HBV) from gibbons was characterized, and the possibility of horizontal transmission between gibbons and humans was examined in a gibbon rehabilitation center in Central Kalimantan, Indonesia. Ten gibbons that were positive for the hepatitis B surface antigen (HBsAg) on arrival and 13 caretakers for t... | 10.1007/s00705-014-2323-9 | 25,559,671 | D000818:Animals; D016000:Cluster Analysis; D004279:DNA, Viral; D016679:Genome, Viral; D006509:Hepatitis B; D006514:Hepatitis B Surface Antigens; D006515:Hepatitis B virus; D006801:Humans; D006922:Hylobates; D007214:Indonesia; D008969:Molecular Sequence Data; D010802:Phylogeny; D018419:Primate Diseases; D017422:Sequence... | Archives of virology | 2,015 | D004279:DNA, Viral; D006514:Hepatitis B Surface Antigens |
Immunohistochemical comparison of transscleral continuous wave 1064-Nd:YAG laser retinopexy and cryoretinopexy. | BACKGROUND
Transcleral retinopexy may be applied with either a cryoprobe or the newer contact laser delivery systems. Tissue responses to these modalities are studied.
METHODS
Transcleral 1064-nm continuous wave neodymium-ytrium-aluminum garnet (CW Nd:YAG) laser retinopexy lesions were compared with retinopexy lesion... | 10.1097/00006982-199401000-00012 | 8,016,463 | D000818:Animals; D002448:Cell Adhesion; D002829:Choroid; D003452:Cryosurgery; D007124:Immunoenzyme Techniques; D007381:Intermediate Filament Proteins; D053685:Laser Therapy; D008264:Macrophages; D010857:Pigment Epithelium of Eye; D011817:Rabbits; D012160:Retina; D009418:S100 Proteins; D012590:Sclera; D014945:Wound Heal... | Retina (Philadelphia, Pa.) | 1,994 | D007381:Intermediate Filament Proteins; D009418:S100 Proteins |
Nanosized (mu12-Pt)Pd164-xPtx(CO)72(PPh3)20 (x approximately 7) containing Pt-centered four-shell 165-atom Pd-Pt core with unprecedented intershell bridging carbonyl ligands: comparative analysis of icosahedral shell-growth patterns with geometrically related Pd145(CO)x(PEt3)30 (x approximately 60) containing capped th... | Presented herein are the preparation and crystallographic/microanalytical/magnetic/spectroscopic characterization of the Pt-centered four-shell 165-atom Pd-Pt cluster, (mu(12)-Pt)Pd(164-x)Pt(x)(CO)(72)(PPh(3))(20) (x approximately 7), 1, that replaces the geometrically related capped three-shell icosahedral Pd(145) clu... | 10.1021/ja073945q | 17,722,929 | D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D053758:Nanoparticles; D009942:Organometallic Compounds; D010165:Palladium; D010720:Phosphines; D010984:Platinum | Journal of the American Chemical Society | 2,007 | D009942:Organometallic Compounds; D010720:Phosphines; D010984:Platinum; D010165:Palladium |
Learning process and improvement of point-of-care ultrasound technique for subxiphoid visualization of the inferior vena cava. | BACKGROUND
Medical residents' training in ultrasonography usually follows the recommendations of the American College of Emergency Physicians (ACEP), even though these do not provide specific technical guidelines. Adequate training is considered to require 25 practical iterations in the majority of ultrasound procedure... | 10.1186/s13089-016-0040-1 | 27,034,059 | Critical ultrasound journal | 2,016 | ||
Carbonyl-carboxylato-ruthenium complexes incorporating diimine ligands and unexpected cyclometalation of carboxylate ligands. | We report two new synthetic routes to the dinuclear Ru(I) complexes, [Ru(I)(2)(RCO(2))(CO)(4)(N( wedge )N)(2)](+) (N( wedge )N = 2,2'-bipyridine or 1,10-phenanthroline derivatives) that use RuCl(3).3H(2)O as a starting material. Direct addition of the bidentate diimine ligand to a methanolic solution of [Ru(CO)(2)Cl(2)... | 10.1021/ic0348401 | 14,731,030 | Inorganic chemistry | 2,004 | ||
COX16 is required for assembly of cytochrome c oxidase in human cells and is involved in copper delivery to COX2. | Cytochrome c oxidase (COX), complex IV of the mitochondrial respiratory chain, is comprised of 14 structural subunits, several prosthetic groups and metal cofactors, among which copper. Its biosynthesis involves a number of ancillary proteins, encoded by the COX-assembly genes that are required for the stabilization an... | 10.1016/j.bbabio.2018.01.004 | 29,355,485 | D000818:Animals; D064113:CRISPR-Cas Systems; D017173:Caenorhabditis elegans; D002413:Cations, Divalent; D003001:Cloning, Molecular; D003067:Coenzymes; D003300:Copper; D004579:Electron Transport; D003576:Electron Transport Complex IV; D015870:Gene Expression; D055786:Gene Knockout Techniques; D005822:Genetic Vectors; D0... | Biochimica et biophysica acta. Bioenergetics | 2,018 | C472291:COX16 protein, S cerevisiae; D002413:Cations, Divalent; D003067:Coenzymes; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; D020033:Protein Isoforms; D021122:Protein Subunits; D011994:Recombinant Proteins; D029701:Saccharomyces cerevisiae Proteins; D003300:Copper; C117108:cytochrome C oxidase subunit ... |
Representation of Women in Pain Medicine Fellowships in the United States, 2017-2018. | OBJECTIVE
To quantify the representation of women trainees and faculty and to explore associations between them at Pain Medicine (PM) fellowship programs in the United States.
SETTING
PM fellowship programs accredited by the Accreditation Council for Graduate Medical Education.
METHODS
All PM programs approved for ... | 10.1093/pm/pnz274 | 31,665,511 | D005257:Fellowships and Scholarships; D005260:Female; D006801:Humans; D009462:Neurology; D010146:Pain; D010822:Physicians, Women; D014481:United States | Pain medicine (Malden, Mass.) | 2,020 | |
Impact of delayed orthodontic care during COVID-19 pandemic: Emergency, disability, and pain. | BACKGROUND
The aim of this study was to evaluate the impact of clinical closure and delayed orthodontic care delivery in terms of types of emergencies, pain intensity, and disability experienced by orthodontic patients during the COVID-19 pandemic.
METHODS
This was a descriptive cross-sectional study using an electro... | 10.1016/j.ejwf.2020.07.004 | 32,900,674 | D000293:Adolescent; D000073640:Betacoronavirus; D000086382:COVID-19; D018352:Coronavirus Infections; D003430:Cross-Sectional Studies; D004185:Disability Evaluation; D004630:Emergencies; D005157:Facial Pain; D005260:Female; D006801:Humans; D008297:Male; D009970:Orthodontics; D010147:Pain Measurement; D058873:Pandemics; ... | Journal of the World federation of orthodontists | 2,020 | |
Native opportunities to stop hypertension: study protocol for a randomized controlled trial among urban American Indian and Alaska Native adults with hypertension. | Introduction
American Indian and Alaska Native (AI/AN) adults experience disproportionate cardiovascular disease (CVD) morbidity and mortality compared to other races, which may be partly attributable to higher burden of hypertension (HTN). Dietary Approaches to Stop Hypertension (DASH) is a high-impact therapeutic die... | 10.3389/fpubh.2023.1117824 | 37,333,529 | D000328:Adult; D006801:Humans; D044467:American Indian or Alaska Native; D002318:Cardiovascular Diseases; D004039:Diet, Sodium-Restricted; D006973:Hypertension; D010865:Pilot Projects; D016032:Randomized Controlled Trials as Topic | Frontiers in public health | 2,023 | |
Efficacy and tolerability of extended-release felodipine and extended-release nifedipine in patients with mild-to-moderate essential hypertension. | The efficacy and tolerability of extended-release felodipine (felodipine-ER) and nifedipine gastrointestinal therapeutic system (nifedipine GITS) were compared in a multicenter, prospective, open-label clinical trial of 277 patients with mild-to-moderate uncomplicated essential hypertension (sitting diastolic blood pre... | 7,982,251 | D000328:Adult; D000368:Aged; D001794:Blood Pressure; D003692:Delayed-Action Preparations; D004334:Drug Administration Schedule; D004361:Drug Tolerance; D004487:Edema; D015736:Felodipine; D005260:Female; D006261:Headache; D006801:Humans; D006973:Hypertension; D008297:Male; D008875:Middle Aged; D009543:Nifedipine; D01144... | Clinical therapeutics | 1,994 | D003692:Delayed-Action Preparations; D009543:Nifedipine; D015736:Felodipine | |
Interspecific transfer of Wolbachia into the mosquito disease vector Aedes albopictus. | Intracellular Wolbachia bacteria are obligate, maternally inherited endosymbionts found frequently in insects and other invertebrates. The evolutionary success of Wolbachia is due in part to an ability to manipulate reproduction. In mosquitoes and many other insects, Wolbachia causes a form of sterility known as cytopl... | 10.1098/rspb.2005.3405 | 16,777,718 | D000330:Aedes; D000818:Animals; D004330:Drosophila; D005260:Female; D005298:Fertility; D007303:Insect Vectors; D008297:Male; D008845:Microinjections; D009865:Oocytes; D011155:Population Control; D012288:Rickettsiaceae Infections; D020577:Wolbachia | Proceedings. Biological sciences | 2,006 | |
A Comparative Evaluation of the Measurement Properties of Three Histological Indices of Mucosal Healing in Ulcerative Colitis: Geboes Score, Robarts Histopathology Index and Nancy Index. | BACKGROUND AND AIMS
To inform their future use in regulated clinical trials to evaluate treatment efficacy hypotheses, the measurement properties of three histological indices, Geboes Score [GS], Robarts Histopathology Index [RHI] and Nancy Index [NI], were evaluated among patients with ulcerative colitis.
METHODS
An... | 10.1093/ecco-jcc/jjad087 | 37,225,135 | D006801:Humans; D003093:Colitis, Ulcerative; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D004724:Endoscopy; D000068879:Adalimumab; D003113:Colonoscopy | Journal of Crohn's & colitis | 2,023 | D000068879:Adalimumab |
Progression of Diabetic Retinopathy and Declining Renal Function in Patients with Type 2 Diabetes. | BACKGROUND
At a university hospital in Korea, we conducted a retrospective study to determine the association of the progression of diabetic retinopathy (DR) with declining renal function in type 2 diabetes.
METHODS
We included a total of 1527 patients with type 2 diabetes who followed up in our diabetes clinic and u... | 10.1155/2020/8784139 | 32,802,891 | D000368:Aged; D003924:Diabetes Mellitus, Type 2; D003928:Diabetic Nephropathies; D003930:Diabetic Retinopathy; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D051436:Renal ... | Journal of diabetes research | 2,020 | |
The frequent evolutionary birth and death of functional promoters in mouse and human. | Promoters are central to the regulation of gene expression. Changes in gene regulation are thought to underlie much of the adaptive diversification between species and phenotypic variation within populations. In contrast to earlier work emphasizing the importance of enhancer evolution and subtle sequence changes at pro... | 10.1101/gr.190546.115 | 26,228,054 | D000818:Animals; D001483:Base Sequence; D017124:Conserved Sequence; D004247:DNA; D004251:DNA Transposable Elements; D019143:Evolution, Molecular; D006801:Humans; D051379:Mice; D016254:Mutagenesis, Insertional; D011401:Promoter Regions, Genetic; D017384:Sequence Deletion; D013045:Species Specificity | Genome research | 2,015 | D004251:DNA Transposable Elements; D004247:DNA |
Distribution of low-density lipoprotein-bound low-molecular-weight thiols: a new analytical approach. | We have recently demonstrated that low-density lipoprotein (LDL) apoprotein is able to bind the most concentrated plasma thiols such as cysteine, cysteinylglycine, and homocysteine by disulfide linkage. However, the LIF CE assay employed to measure linked thiols was not sensitive enough to verify whether low concentrat... | 10.1002/elps.200500762 | 16,817,161 | D001055:Apolipoproteins B; D019075:Electrophoresis, Capillary; D006801:Humans; D008077:Lipoproteins, LDL; D008970:Molecular Weight; D013438:Sulfhydryl Compounds | Electrophoresis | 2,006 | D001055:Apolipoproteins B; D008077:Lipoproteins, LDL; D013438:Sulfhydryl Compounds |
Chemotherapy and resection for gastric cancer with synchronous liver metastases. | AIM
To investigate the effect of surgery and chemotherapy for gastric cancer with multiple synchronous liver metastases (GCLM).
METHODS
A total of 114 patients were entered in this study, and 20 patients with multiple synchronous liver metastases were eligible. After screening with preoperative chemotherapy, 20 patie... | 10.3748/wjg.v19.i13.2097 | 23,599,631 | D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols; D002945:Cisplatin; D000077143:Docetaxel; D004338:Drug Combinations; D005260:Female; D005472:Fluorouracil; D006031:Glycosylation; D006801:Humans; D008113:Liver Neoplasms; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D... | World journal of gastroenterology | 2,013 | D004338:Drug Combinations; D043823:Taxoids; C079198:S 1 (combination); D005641:Tegafur; D000077143:Docetaxel; D010094:Oxonic Acid; D002945:Cisplatin; D005472:Fluorouracil |
Animal Eyes: Filtering Out the Background. | Animals use photonic structures in their eyes to form images, enhance sensitivity and provide camouflage. A recent exciting discovery shows that the eyes of some larval mantis shrimp possess photonic crystals that function as color filters to detect bioluminescence. | 10.1016/j.cub.2019.08.035 | 31,593,672 | D000818:Animals; D003116:Color; D003445:Crustacea; D007814:Larva; D020050:Mantodea; D012160:Retina | Current biology : CB | 2,019 | |
Green synthesis of silver nanoparticles using Indian male fern (Dryopteris Cochleata), operational parameters, characterization and bioactivity on Naja naja venom neutralization. | Snakebite is considered as one of the acute severe medical problems across the world. Snake venoms composed of various group of toxins, enzymes and non-toxic enzymes. Phospholipases A2 present in Naja naja snake venom plays a significant role in lipid signalling and contributes to different inflammation in the human bo... | 10.1093/toxres/tfaa070 | 33,178,431 | Toxicology research | 2,020 | ||
Effects of human cord blood mesenchymal stem cells on cutaneous wound healing in leprdb mice. | PURPOSE
In the present study, we used the diabetic mouse as a model of delayed wound healing to investigate the effects of human cord blood mesenchymal stem cells (CB-MSC) on wound healing.
METHODS
A delayed wound healing model was used by db/db mice. Study models were divided by an injection of human CB-MSC with pho... | 10.1097/SAP.0b013e3181d9aae2 | 20,948,411 | D000818:Animals; D003921:Diabetes Mellitus, Experimental; D005312:Fetal Blood; D006801:Humans; D015552:Injections, Intralesional; D007275:Injections, Intravenous; D045164:Mesenchymal Stem Cell Transplantation; D051379:Mice; D008810:Mice, Inbred C57BL; D008817:Mice, Mutant Strains; D012867:Skin; D016212:Transforming Gro... | Annals of plastic surgery | 2,010 | D016212:Transforming Growth Factor beta; D042461:Vascular Endothelial Growth Factor A |
Network analysis of cell adhesion: Adhesomes as context-defined subnetworks. | Complex systems consisting of diverse interlinked elements are often represented as networks and are described according to the principles of network analysis. Among the networks of biological interest, several protein-protein interactomes have been reported in recent years, mostly in conjunction with high-throughput a... | 10.4161/cib.2.1.7351 | 19,704,858 | Communicative & integrative biology | 2,009 | ||
Complex upper arm reconstruction using an antero-lateral thigh free flap after an extravasation of Yttrium-90-ibritumomab Tiuxetan: A case report and literature review. | Yttrium-90-Ibritumomab Tiuxetan (Zevalin®) is used in the treatment of non- Hodgkin's lymphoma. Extravasation is an iatrogenic complication that is fortunately rare. However, the treatment of this complication is often complex due to the risk of extensive skin necrosis and unpredictable evolution of localized irradiati... | 10.1016/j.anplas.2017.11.007 | 29,290,464 | D000368:Aged; D000911:Antibodies, Monoclonal; D001132:Arm; D005119:Extravasation of Diagnostic and Therapeutic Materials; D058752:Free Tissue Flaps; D006801:Humans; D020522:Lymphoma, Mantle-Cell; D008297:Male; D009336:Necrosis; D019651:Plastic Surgery Procedures; D013848:Thigh | Annales de chirurgie plastique et esthetique | 2,018 | D000911:Antibodies, Monoclonal; C422802:ibritumomab tiuxetan |
The case for spatial analysis in evaluation to reduce health inequities. | The article begins by giving an overview of spatial thinking concepts that are relevant to evaluation. The article relates the spatial perspective to both a realist evaluation and a randomized control trial perspective in evaluation to demonstrate the benefits of a spatialized program and evaluation perspective. The ar... | 22,469,340 | D054624:Health Status Disparities; D006801:Humans; D020380:Needs Assessment; D011340:Problem Solving; D015397:Program Evaluation; D062206:Spatial Analysis | Evaluation and program planning | 2,013 | ||
The callipyge locus: evidence for the trans interaction of reciprocally imprinted genes. | The callipyge phenotype in sheep is an inherited muscular hypertrophy that affects only heterozygous individuals who receive the CLPG mutation from their father. The CLPG mutation is a single nucleotide substitution in what is probably a long-range control element (LRCE) within the DLK1-GTL2 imprinted domain. Recent re... | 10.1016/S0168-9525(03)00082-9 | 12,711,215 | D000818:Animals; D005799:Genes, Dominant; D018392:Genomic Imprinting; D006023:Glycoproteins; D006801:Humans; D006984:Hypertrophy; D018482:Muscle, Skeletal; D009135:Muscular Diseases; D011506:Proteins; D062085:RNA, Long Noncoding; D012756:Sheep; D012757:Sheep Diseases | Trends in genetics : TIG | 2,003 | D006023:Glycoproteins; C498907:MEG3 non-coding RNA, human; D011506:Proteins; D062085:RNA, Long Noncoding |
Phenotypic and Physiological Characterization of the Epibiotic Interaction Between TM7x and Its Basibiont Actinomyces. | Despite many examples of obligate epibiotic symbiosis (one organism living on the surface of another) in nature, such an interaction has rarely been observed between two bacteria. Here, we further characterize a newly reported interaction between a human oral obligate parasitic bacterium TM7x (cultivated member of Cand... | 10.1007/s00248-015-0711-7 | 26,597,961 | D000190:Actinomyces; D001419:Bacteria; D018407:Bacterial Physiological Phenomena; D006801:Humans; D009055:Mouth; D010641:Phenotype; D013559:Symbiosis | Microbial ecology | 2,016 | |
Little Cigars vs 3R4F Cigarette: Physical Properties and HPHC Yields. | OBJECTIVE
Our objective was to characterize physical properties and semivolatile harmful and potentially harmful constituent yields in the mainstream smoke (MSS) of 4 popular little cigars compared to the 3R4F reference cigarette.
METHODS
We used the ISO and Canadian Intense Regimen protocols to generate MSS for Chey... | 10.18001/TRS.3.4.7 | 29,911,130 | Tobacco regulatory science | 2,017 | ||
Mössbauer studies of electrophoretically purified monoferric and diferric human transferrin. | Electrophoretically purified 57Fe-enriched monoferric and diferric human transferrins and selectively labeled complexes ([C-56Fe,N-57Fe]transferrin and [C-57Fe,N-56Fe]transferrin) were studied by Mössbauer spectroscopy. The data were recorded at 4.2 K over a wide range of applied magnetic fields (0.05-6 T) and were ana... | 10.1007/BF01128014 | 3,152,869 | D001665:Binding Sites; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007501:Iron; D007503:Iron Isotopes; D015204:Spectroscopy, Mossbauer; D014168:Transferrin | Biology of metals | 1,988 | D007503:Iron Isotopes; D014168:Transferrin; D007501:Iron |
Isolation and properties of the rabbit skeletal muscle protein inhibitor of adenosine 3',5'-monophosphate dependent protein kinases. | The heat-stable protein inhibitor (Walsh, D. A., et al. (1971), J. Biol. Chem. 246, 1977--1985) of the cyclic adenosine 3',5'-monophosphate dependent protein kinase has been isolated in pure form from rabbit skeletal muscle after a 430 000-fold purification with a 47% yield. The four-step procedure involves sequentiall... | 10.1021/bi00633a006 | 196,623 | D000596:Amino Acids; D000818:Animals; D000242:Cyclic AMP; D004791:Enzyme Inhibitors; D007526:Isoelectric Point; D007700:Kinetics; D008970:Molecular Weight; D009132:Muscles; D047428:Protein Kinase Inhibitors; D011494:Protein Kinases; D011817:Rabbits; D013053:Spectrophotometry | Biochemistry | 1,977 | D000596:Amino Acids; D004791:Enzyme Inhibitors; D047428:Protein Kinase Inhibitors; D000242:Cyclic AMP; D011494:Protein Kinases |
Predicted genotypic resistance to the novel entry inhibitor, BMS-378806, among HIV-1 isolates of subtypes A to G. | BMS-378806 targets virus entry by inhibiting the binding of HIV-1 gp120 to the CD4 receptor. Env sequences (n = 1226) of subtypes A-G were analysed to determine the frequency of mutations associated with resistance to BMS-378806. In line with reported sensitivity data, background genotypic resistance to BMS-378806 amon... | 10.1097/00002030-200411190-00015 | 15,577,547 | D024882:Drug Resistance, Viral; D005814:Genes, Viral; D015752:Genes, env; D005838:Genotype; D015497:HIV-1; D009154:Mutation; D010879:Piperazines | AIDS (London, England) | 2,004 | C477855:BMS-378806; D010879:Piperazines |
The role of biomarkers in the early detection of anthracycline-induced cardiotoxicity in children: a review of the literature. | Anthracycline-induced cardiotoxicity can cause serious health problems for an increasing number of children surviving childhood malignancies. Early detection of cardiac failure is critically important for the prevention and management of anthracycline-induced cardiotoxicity. The aim of this research was to determine th... | 10.1080/08880010802244001 | 18,850,478 | D018943:Anthracyclines; D015415:Biomarkers; D002648:Child; D042241:Early Diagnosis; D006331:Heart Diseases; D006801:Humans; D020097:Natriuretic Peptide, Brain; D009369:Neoplasms; D010446:Peptide Fragments; D019210:Troponin I; D020107:Troponin T | Pediatric hematology and oncology | 2,008 | D018943:Anthracyclines; D015415:Biomarkers; D010446:Peptide Fragments; D019210:Troponin I; D020107:Troponin T; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain |
A SNP in GmBADH2 gene associates with fragrance in vegetable soybean variety "Kaori" and SNAP marker development for the fragrance. | Fragrance in soybean is due to the presence of 2-acetyl-1-pyrroline (2AP). BADH2 gene coding for betaine aldehyde dehydrogenase has been identified as the candidate gene responsible for fragrance in rice (Oryza sativa L.). In this study, using the RIL population derived from fragrant soybean cultivar "Kaori" and non-fr... | 10.1007/s00122-010-1467-6 | 21,046,066 | D000595:Amino Acid Sequence; D001483:Base Sequence; D050728:Betaine-Aldehyde Dehydrogenase; D002849:Chromatography, Gas; D018744:DNA, Plant; D017343:Genes, Plant; D056726:Genetic Association Studies; D008040:Genetic Linkage; D005819:Genetic Markers; D007178:Inbreeding; D008969:Molecular Sequence Data; D009812:Odorants;... | TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik | 2,011 | D018744:DNA, Plant; D005819:Genetic Markers; D010940:Plant Proteins; D011758:Pyrroles; D050728:Betaine-Aldehyde Dehydrogenase; C426303:2-acetyl-1-pyrroline |
Evaluation of the national tuberculosis surveillance program in Haiti. | OBJECTIVE
To assess the quality of tuberculosis (TB) surveillance in Haiti, including whether underreporting from facilities to the national level contributes to low national case registration.
METHODS
We collected 2010 and 2012 TB case totals, reviewed laboratory registries, and abstracted individual TB case reports... | 10.5588/ijtld.15.0051 | 26,260,822 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016208:Databases, Factual; D005260:Female; D006205:Haiti; D006268:Health Facilities; D006801:Humans; D008297:Male; D008875:Middle Aged; D015397:Program Evaluation; D062486:Public Health Surveillance; D012042:Registries; D014376:Tuberculosis; D... | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease | 2,015 | |
Hints for Genetic and Clinical Differentiation of Adult-Onset Monogenic Autoinflammatory Diseases. | Monogenic autoinflammatory diseases (mAIDs) are inherited errors of innate immunity characterized by systemic inflammation recurring with variable frequency and involving the skin, serosal membranes, synovial membranes, joints, the gastrointestinal tube, and/or the central nervous system, with reactive amyloidosis as a... | 10.1155/2019/3293145 | 32,082,075 | D000328:Adult; D001327:Autoimmune Diseases; D010505:Familial Mediterranean Fever; D056660:Hereditary Autoinflammatory Diseases; D006801:Humans; D007249:Inflammation; D011788:Quality of Life | Mediators of inflammation | 2,019 | |
[Long-term complete response in a patient with breast cancer and bone and pleura metastases after treatment with a combination of S-1 and zoledronic acid]. | We report a long-term complete response (CR) in a patient with postoperative recurrent breast cancer and bone and pleura metastases after treatment with a combination of S-1 and zoledronic acid. We administered 4 courses of tri-weekly CE (epirubicin 75 mg/m2, cyclophosphamide 600 mg/m2) and 12 courses of weekly paclita... | 20,647,717 | D014408:Biomarkers, Tumor; D050071:Bone Density Conservation Agents; D001859:Bone Neoplasms; D001943:Breast Neoplasms; D004164:Diphosphonates; D004338:Drug Combinations; D006801:Humans; D007093:Imidazoles; D010094:Oxonic Acid; D010997:Pleural Neoplasms; D005641:Tegafur; D013997:Time Factors; D014057:Tomography, X-Ray C... | Gan to kagaku ryoho. Cancer & chemotherapy | 2,010 | D014408:Biomarkers, Tumor; D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D004338:Drug Combinations; D007093:Imidazoles; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D000077211:Zoledronic Acid | |
Functional connectivity between immune cells mediated by tunneling nanotubules. | Intercellular signals can be transmitted through neuronal synapses or through gap junctions, with the latter mediating transmission of calcium fluxes and small molecules between cells. We show here that a third form of communication between cells can be mediated by tunneling nanotubules (TNT). When myeloid-lineage dend... | 10.1016/j.immuni.2005.08.009 | 16,169,503 | D000818:Animals; D002118:Calcium; D002450:Cell Communication; D017077:Culture Media, Conditioned; D003713:Dendritic Cells; D004926:Escherichia coli; D006801:Humans; D007365:Intercellular Junctions; D018613:Microscopy, Confocal; D008855:Microscopy, Electron, Scanning; D009000:Monocytes; D043942:Nanotubes; D010812:Physic... | Immunity | 2,005 | D017077:Culture Media, Conditioned; D002118:Calcium |
Comparative study of traditional long incision vein harvesting and multiple incisions with small skin bridges in patients with coronary artery bypass grafting at King Abdullah University Hospital--Jordan. | OBJECTIVE
Saphenous vein harvesting can be associated with wound complications, incision pain, infection, and poor cosmetic outcome. The objective of our study is to determine the difference in wound complication and infection rates between two saphenous vein harvesting techniques, long incision versus multiple short i... | 20,802,911 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001026:Coronary Artery Bypass; D005260:Female; D006801:Humans; D007597:Jordan; D007866:Leg; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012501:Saphenous Vein; D013530:Surgical Wound Infection; D020858:Tissue and Organ Harvesting | Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular | 2,010 | ||
Dihydrofolate reductase 19-bp deletion polymorphism modifies the association of folate status with memory in a cross-sectional multi-ethnic study of adults. | BACKGROUND
Folate status has been positively associated with cognitive function in many studies; however, some studies have observed associations of poor cognitive outcomes with high folate. In search of an explanation, we hypothesized that the association of folate with cognition would be modified by the interaction o... | 10.3945/ajcn.115.111054 | 26,354,538 | D001741:Black or African American; D000368:Aged; D000369:Aged, 80 and over; D001900:Boston; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D005492:Folic Acid; D005494:Folic Acid Deficiency; D017353:Gene Deletion; D056726:Genetic Association Studies; D006630:Hispanic or Latino; D006801:Humans; ... | The American journal of clinical nutrition | 2,015 | D005492:Folic Acid; D013762:Tetrahydrofolate Dehydrogenase |
Prognostic value of serum neurofilaments in patients with clinically isolated syndromes. | OBJECTIVE
To assess the prognostic role of serum neurofilament light chains (NfL) for clinically defined multiple sclerosis (CDMS) and McDonald 2017 multiple sclerosis (MS) in patients with clinically isolated syndromes (CIS).
METHODS
We retrospectively analyzed data of patients admitted to our neurologic department ... | 10.1212/WNL.0000000000006902 | 30,635,483 | D000328:Adult; D001921:Brain; D003711:Demyelinating Diseases; D018450:Disease Progression; D005260:Female; D006801:Humans; D007382:Intermediate Filaments; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis; D016900:Neurofilament Proteins; D011379:Prognosis; D055815:Young Adult | Neurology | 2,019 | D016900:Neurofilament Proteins; C044882:neurofilament protein L |
Oxygen adsorption on the Al₉Co₂(001) surface: first-principles and STM study. | Atomic oxygen adsorption on a pure aluminum terminated Al9Co2(001) surface is studied by first-principle calculations coupled with STM measurements. Relative adsorption energies of oxygen atoms have been calculated on different surface sites along with the associated STM images. The local electronic structure of the mo... | 10.1088/0953-8984/25/35/355003 | 23,883,551 | D000327:Adsorption; D017607:Aluminum Compounds; D001665:Binding Sites; D002245:Carbon Dioxide; D003198:Computer Simulation; D008956:Models, Chemical; D008958:Models, Molecular; D008968:Molecular Conformation; D010100:Oxygen; D013499:Surface Properties | Journal of physics. Condensed matter : an Institute of Physics journal | 2,013 | D017607:Aluminum Compounds; D002245:Carbon Dioxide; D010100:Oxygen |
Role of uteroferrin in transplacental iron transport in the pig. | The pig possesses a noninvasive, diffuse type of epitheliochorial placentation in which the blood supply of the mother is well separated from the absorptive surface of the chorion, a feature that must complicate the movement of nutrient molecules across the placenta. Evidence is presented that a protein synthesized and... | 3,527,760 | D000135:Acid Phosphatase; D000818:Animals; D001665:Binding Sites; D001692:Biological Transport; D004848:Epithelium; D005260:Female; D005333:Fetus; D006651:Histocytochemistry; D007501:Iron; D007527:Isoenzymes; D008667:Metalloproteins; D009751:Nutritional Requirements; D010920:Placenta; D011247:Pregnancy; D013045:Species... | Federation proceedings | 1,986 | D007527:Isoenzymes; D008667:Metalloproteins; D014168:Transferrin; D007501:Iron; D000135:Acid Phosphatase; D000071681:Tartrate-Resistant Acid Phosphatase | |
Uncovering the Role of Trioctylphosphine on Colloidal and Emission Stability of Sb-Alloyed Cs2NaInCl6 Double Perovskite Nanocrystals. | Doping and compositional tuning of Cs2AInCl6 (A = Ag, Na) double perovskite nanocrystals (PNCs) is considered a promising strategy toward the development of light-emitting sources for applications in solution-processed optoelectronic devices. Oleic acid and oleylamine are by far the most often used surface capping liga... | 10.1021/acsami.1c10782 | 34,582,162 | ACS applied materials & interfaces | 2,021 | ||
Changes in the Plasma Proteome of Manduca sexta Larvae in Relation to the Transcriptome Variations after an Immune Challenge: Evidence for High Molecular Weight Immune Complex Formation. | Manduca sextais a lepidopteran model widely used to study insect physiological processes, including innate immunity. In this study, we explored the proteomes of cell-free hemolymph from larvae injected with a sterile buffer (C for control) or a mixture of bacteria (I for induced). Of the 654 proteins identified, 70 sho... | 10.1074/mcp.M115.054296 | 26,811,355 | D000818:Animals; D005216:Fat Body; D005786:Gene Expression Regulation; D006458:Hemolymph; D007113:Immunity, Innate; D019476:Insect Proteins; D007814:Larva; D018402:Manduca; D020543:Proteome; D059467:Transcriptome | Molecular & cellular proteomics : MCP | 2,016 | D019476:Insect Proteins; D020543:Proteome |
[Study of the Raman-AFM system for simultaneous measurements of Raman spectrum and micro/nano-structures]. | This paper proposes a novel technique of Raman-atomic force microscopy (AFM) combining micro region Raman spectroscopy and AFM imaging. An in-situ probe unit which can simultaneously realize the detection of Raman spectrum and the measurement of AFM image was designed, and a related Raman-AFM system was constructed. Us... | 22,715,770 | Guang pu xue yu guang pu fen xi = Guang pu | 2,012 | |||
Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana. | The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bi... | 10.1128/MRA.00175-21 | 33,927,034 | Microbiology resource announcements | 2,021 | ||
Transfusion-dependent beta-thalassemia: in vitro characterization of peripheral blood multipotential and committed progenitor cells. | Conditions for the in vitro culture of multipotential and committed progenitor cells obtained from the peripheral blood of transfusion-dependent beta-thalassemic individuals have been determined. When stimulated by either human placental-conditioned medium (HPCM), phytohemagglutinin-stimulated leukocyte-conditioned med... | 3,569,442 | D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D003470:Culture Media; D004920:Erythropoiesis; D004921:Erythropoietin; D005914:Globins; D006410:Hematopoiesis; D006412:Hematopoietic Stem Cells; D006801:Humans; D013789:Thalassemia | Experimental hematology | 1,987 | D003470:Culture Media; D004921:Erythropoietin; D005914:Globins | |
A surface-based technique for warping three-dimensional images of the brain. | The authors have devised, implemented, and tested a fast, spatially accurate technique for calculating the high-dimensional deformation field relating the brain anatomies of an arbitrary pair of subjects. The resulting three-dimensional (3-D) deformation map can be used to quantify anatomic differences between subjects... | 10.1109/42.511745 | 18,215,923 | IEEE transactions on medical imaging | 1,996 | ||
Synthesis of Functionalized Organoboron/Silicon Compounds by Copper-Catalyzed Coupling of Alkylsilyl Peroxides and Diboron/Silylborane Reagents. | The facile synthesis of functionalized organoboron/silicon compounds by copper-catalyzed coupling of alkylsilyl peroxides and diboron/silylborane reagents is reported. The reactions proceed smoothly under mild, neutral conditions in short reaction times to generate organoboron/silicon compounds bearing a ketone moiety,... | 10.1021/acs.orglett.9b00874 | 30,912,448 | Organic letters | 2,019 | ||
The development of animal behavior: from Lorenz to neural nets. | In the study of behavioral development both causal and functional approaches have been used, and they often overlap. The concept of ontogenetic adaptations suggests that each developmental phase involves unique adaptations to the environment of the developing animal. The functional concept of optimal outbreeding has le... | 10.1007/s001140050582 | 10,189,629 | D000818:Animals; D001522:Behavior, Animal; D005075:Biological Evolution; D001921:Brain; D007858:Learning; D008959:Models, Neurological; D008960:Models, Psychological; D009415:Nerve Net; D010465:Perception | Die Naturwissenschaften | 1,999 | |
A new biologically active triterpenoid saponin from the leaves of Lepidagathis hyalina Nees. | A new biologically active triterpenoid saponin m.f. C42H68O13, m.p. 315 degrees-317 degrees C was isolated from the ethyl acetate soluble fraction of the methanolic extract of the leaves of Lepidagathis hyalina. Its structure was characterized as 3-beta-O-[alpha-L-rhamnopyranosyl(1-->4)O-beta-D-glucopyranosyl]16-alpha-... | 10.1080/10575630108041298 | 11,841,115 | D027901:Acanthaceae; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D016282:Aspartic Acid Endopeptidases; D001230:Aspergillus; D001407:Bacillus; D002851:Chromatography, High Pressure Liquid; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli; D005670:Fusarium; D... | Natural product letters | 2,001 | C447179:3-beta-O-(alpha-L-rhamnopyranosyl(1-4)O-beta-D-glucopyranosyl)16-alpha-hydroxy-olean-12-en(13)-28-oic acid; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D012503:Saponins; D014315:Triterpenes; D009828:Oleanolic Acid; D016282:Aspartic Acid Endopeptidases; C022772:Asperg... |
Size-Dependent Exciton Formation Dynamics in Colloidal Silicon Quantum Dots. | We report size-dependent exciton formation dynamics within colloidal silicon quantum dots (Si QDs) using time-resolved terahertz (THz) spectroscopy measurements. THz photoconductivity measurements are used to distinguish the initially created hot carriers from excitons that form at later times. At early pump/probe dela... | 10.1021/acsnano.5b07073 | 26,811,876 | ACS nano | 2,016 | ||
Assessing chromosome 22 microdeletions in meningioma with new polymorphic DNA markers. | In an approach to identify new candidates for tumor related genes, a set of established and new polymorphic DNA markers (simple sequence repeats) was used in menigioma samples to test for deletions within human chromosome 22. For this purpose, cytogenetically well characterized tumors were applied and those with monoso... | 10.3892/or.6.5.1147 | 10,425,317 | D014408:Biomarkers, Tumor; D002872:Chromosome Deletion; D002892:Chromosomes, Human, Pair 22; D004273:DNA, Neoplasm; D005819:Genetic Markers; D006801:Humans; D008577:Meningeal Neoplasms; D008579:Meningioma; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid | Oncology reports | 1,999 | D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm; D005819:Genetic Markers |
Early posttransplantation hypertension and poor long-term renal allograft survival in pediatric patients. | OBJECTIVE
To evaluate the effect of early hypertension on long-term allograft survival in children with kidney transplantation.
STUDY DESIGN
Data from a total of 159 patients (mean age, 12.8+/-4.8 years) who underwent kidney transplantation between 1978 and 1998 and whose allograft was functioning for at least 1 year... | 10.1016/S0022-3476(03)00209-9 | 12,915,832 | D000208:Acute Disease; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D006973:Hypertension; D007676:Kidney Failure, Chronic; D016030:Kidney Transplantation; D008297:Male; D015999:Multivariate Analysis; D011183:Postoper... | The Journal of pediatrics | 2,003 | |
Implementing two treatment approaches to childhood dysarthria. | The paucity of evidence and detail in the literature regarding speech treatment for children with dysarthria due to cerebral palsy (CP) renders it difficult for researchers to replicate studies and make further inroads into this area in need of exploration. Furthermore, for speech-language pathologists (SLPs) wishing t... | 10.3109/17549507.2014.894123 | 24,673,184 | D002648:Child; D002675:Child, Preschool; D004401:Dysarthria; D006801:Humans; D013070:Speech Therapy | International journal of speech-language pathology | 2,014 | |
Ureteral stents increase risk of postoperative acute kidney injury following colorectal surgery. | BACKGROUND
Ureteral stents are commonly placed before colorectal resection to assist in identification of ureters and prevent injury. Acute kidney injury (AKI) is a common cause of morbidity and increased cost following colorectal surgery. Although previously associated with reflex anuria, prophylactic stents have not ... | 10.1007/s00464-018-6054-y | 29,340,810 | D058186:Acute Kidney Injury; D000368:Aged; D003107:Colorectal Surgery; D005260:Female; D017721:Hospital Costs; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D014513:Ureter | Surgical endoscopy | 2,018 | |
When Does the Cytokine Storm Begin in COVID-19 Patients? A Quick Score to Recognize It. | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that is responsible for coronavirus disease 2019 (COVID-19), which has rapidly spread across the world, becoming a pandemic. The "cytokine storm" (CS) in COVID-19 leads to the worst stage of illness, and its timely control through immunomodulator... | 10.3390/jcm10020297 | 33,467,466 | Journal of clinical medicine | 2,021 | ||
5-(123)I-A-85380 binding to the α4β2-nicotinic receptor in mild cognitive impairment. | Treatments currently licensed for Alzheimer's dementia target cholinergic brain systems. In vivo nicotinic receptor binding may provide an early marker of illness and treatment suitability. In this pilot, we examined nine patients with amnestic mild cognitive impairment (MCI) and 10 age and education matched healthy vo... | 10.1016/j.neurobiolaging.2008.10.008 | 19,036,475 | D000368:Aged; D000369:Aged, 80 and over; D001384:Azetidines; D001921:Brain; D016022:Case-Control Studies; D003072:Cognition Disorders; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D008032:Limbic System; D008297:Male; D016555:Matched-Pair Analysis; D009483:Neuropsychological Tests; D020534:Parahippocamp... | Neurobiology of aging | 2,010 | C426745:5-iodo-3-(2-azetidinylmethoxy)pyridine; D001384:Azetidines; D007457:Iodine Radioisotopes; D011725:Pyridines; D011978:Receptors, Nicotinic; C403531:nicotinic receptor alpha4beta2 |
Inducing labor with oral prostaglandin E2 tablets. | Labor was successfully induced by forewater amniotomy and oral administration of prostaglandin E2 tablets in 91.3% of 153 women with singleton pregnancies. Deliveries occurred within 12 hours for more than 90% of the successfully induced patients. Although not statistically significant, a higher pelvic score appeared t... | 10.1002/j.1879-3479.1977.tb00722.x | 28,975 | D000284:Administration, Oral; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007751:Labor, Induced; D011247:Pregnancy; D011458:Prostaglandins E; D013607:Tablets; D013997:Time Factors | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics | 1,978 | D011458:Prostaglandins E; D013607:Tablets |
Rearrangements involving 12p12 in two cases of cardiac myxoma. | Recently, we reported on the cytogenetic analysis of a case of cardiac myxoma, revealing a 46,XY,der(7)t(7;17)(p21;p11), add (10) (q22), add (12) (p12), del(17)(p11) chromosomal pattern. In this article we present the cytogenetic analysis of another case of cardiac myxoma, in which we found several clonal and nonclonal... | 10.1016/0165-4608(94)00268-g | 7,664,247 | D000368:Aged; D002881:Chromosomes, Human, Pair 12; D015321:Gene Rearrangement; D006338:Heart Neoplasms; D006801:Humans; D007621:Karyotyping; D008297:Male; D009232:Myxoma | Cancer genetics and cytogenetics | 1,995 | |
[Angiogenic effect of bone marrow mesenchymal stem cells transfected with human VEGF gene on myocardial infarcts in rats]. | OBJECTIVE
To evaluate the angiogenic effect of the bone marrow mesenchymal stem cells (MSCs) transfected with human vascular endothelial growth factor (VEGF(165)) gene on myocardial infarcts in rats.
METHODS
The animal model of heart ischemic was established by ligating the left anterior descending coronary artery in... | 17,062,948 | D000818:Animals; D001854:Bone Marrow Cells; D003326:Coronary Circulation; D006801:Humans; D008297:Male; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells; D009203:Myocardial Infarction; D018919:Neovascularization, Physiologic; D051381:Rats; D017208:Rats, Wistar; D014162:Transfection; D042461... | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences | 2,006 | D042461:Vascular Endothelial Growth Factor A | |
Chemotherapy-induced oral mucositis. Prevention and management. | Oral mucositis is a frequent and potentially severe complication of chemotherapy which has a considerable impact on patient quality of life. While the management of other chemotherapy-related toxicities has improved, the incidence of mucositis is increasing. A critical review of the literature published between 1985 an... | 10.2165/00002512-200017040-00002 | 11,087,004 | D000970:Antineoplastic Agents; D017679:Cryotherapy; D005472:Fluorouracil; D006801:Humans; D009061:Mouth Mucosa; D009910:Oral Hygiene; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D013280:Stomatitis | Drugs & aging | 2,000 | D000970:Antineoplastic Agents; D005472:Fluorouracil |
Paracetamol (acetaminophen) pack size restrictions and poisoning severity: time trends in enquiries to a UK poisons centre. | BACKGROUND AND OBJECTIVE
In September 1998, legislation was introduced in the United Kingdom to limit paracetamol pack sizes to 16 tablets of 500 mg at general sales outlets and 32 tablets of 500 mg at pharmacies. The effect of the regulations on severity of paracetamol poisoning is unclear. The aim of this study was t... | 10.1111/j.1365-2710.2007.00842.x | 17,875,110 | D000082:Acetaminophen; D017677:Age Distribution; D018712:Analgesics, Non-Narcotic; D062787:Drug Overdose; D004349:Drug Packaging; D005260:Female; D006801:Humans; D007880:Legislation, Drug; D008297:Male; D011039:Poison Control Centers; D011041:Poisoning; D017678:Sex Distribution; D006113:United Kingdom | Journal of clinical pharmacy and therapeutics | 2,007 | D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen |
K-ras exon 4A has a tumour suppressor effect on carcinogen-induced murine colonic adenoma formation. | K-ras encodes two isoforms, K-ras 4A and 4B, that are jointly affected by K-ras activating mutations, which are prevalent in colorectal cancer (CRC). CRC shows alterations in the expressed K-ras 4A : 4B isoform ratio in favour of K-ras 4B, in tumours both with and without K-ras mutations. The present study evaluated wh... | 10.1002/path.2672 | 20,087,880 | D019813:1,2-Dimethylhydrazine; D000236:Adenoma; D000818:Animals; D017209:Apoptosis; D002273:Carcinogens; D049109:Cell Proliferation; D002471:Cell Transformation, Neoplastic; D003110:Colonic Neoplasms; D004789:Enzyme Activation; D005091:Exons; D016147:Genes, Tumor Suppressor; D011905:Genes, ras; D020935:MAP Kinase Signa... | The Journal of pathology | 2,010 | D002273:Carcinogens; D051057:Proto-Oncogene Proteins c-akt; C495971:Hras protein, mouse; D016283:Proto-Oncogene Proteins p21(ras); D019813:1,2-Dimethylhydrazine |
Histiocytic malignancies. Morphologic, immunologic, and enzymatic heterogeneity. | We have studied 14 hematopoietic malignancies with histologic features of histiocytic differentiation, using frozen section immunologic stains, plastic section enzyme histochemistry, and paraffin section immunocytochemistry. There was morphologic, immunologic, and enzymatic heterogeneity, including findings in seven ca... | 6,204,546 | D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D005629:Frozen Sections; D006801:Humans; D008113:Liver Neoplasms; D008206:Lymphatic Diseases; D008223:Lymphoma; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms; D013160:Splenic Neoplasms; D013194:Staining and Labeling; D013601:T-L... | The American journal of surgical pathology | 1,984 | ||
Evidence that selenium induces growth retardation through reduced growth hormone and somatomedin C production. | Growth retardation has long been known to be a major characteristic in selenium-intoxicated animals. As selenium is known to accumulate in the anterior pituitary, especially in the secretory granules of the somatotroph, we have investigated the GH secretion after GH-releasing factor 40 stimulation and the somatomedin C... | 10.1210/endo-120-2-659 | 3,803,296 | D000818:Animals; D006128:Growth; D013006:Growth Hormone; D007334:Insulin-Like Growth Factor I; D007700:Kinetics; D008297:Male; D010902:Pituitary Gland; D051381:Rats; D011919:Rats, Inbred Strains; D012643:Selenium; D013002:Somatomedins | Endocrinology | 1,987 | D013002:Somatomedins; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone; D012643:Selenium |
Priorities for research consortia on Alzheimer's disease. | Coordination and harmonization of efforts between five major research consortia on Alzheimer's disease may increase our understanding of this condition and improve our therapeutic approaches. Specific opportunities include a registry for families with early onset dementia, a study registry, minimal data sets, validatio... | 10.1016/j.jalz.2010.05.2017 | 20,630,416 | D017668:Age of Onset; D000544:Alzheimer Disease; D002986:Clinical Trials as Topic; D003627:Data Interpretation, Statistical; D032984:Ethics, Research; D006801:Humans; D008137:Longitudinal Studies; D016032:Randomized Controlled Trials as Topic; D012042:Registries; D015203:Reproducibility of Results; D012106:Research; D0... | Alzheimer's & dementia : the journal of the Alzheimer's Association | 2,010 | |
DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription. | Human DOR/TP53INP2 displays a unique bifunctional role as a modulator of autophagy and gene transcription. However, the domains or regions of DOR that participate in those functions have not been identified. Here we have performed structure/function analyses of DOR guided by identification of conserved regions in the D... | 10.1371/journal.pone.0034034 | 22,470,510 | D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D000818:Animals; D001343:Autophagy; D002352:Carrier Proteins; D057809:HEK293 Cells; D006367:HeLa Cells; D006360:Heat-Shock Proteins; D006801:Humans; D007448:Invertebrates; D008969:Molecular Sequence Data; D009154:Mutation; D009687:Nuclear Proteins; D017434:P... | PloS one | 2,012 | D002352:Carrier Proteins; D006360:Heat-Shock Proteins; D009687:Nuclear Proteins; D034741:RNA, Small Interfering; C429767:TP53INP1 protein, human; C501283:TP53INP2 protein, human |
Bacterial community analysis of beef cattle feedlots reveals that pen surface is distinct from feces. | The surface of beef cattle feedlot pens is commonly conceptualized as being packed uncomposted manure. Despite the important role that the feedlot pen may play in the transmission of veterinary and zoonotic pathogens, the bacterial ecology of feedlot surface material is not well understood. Our present study characteri... | 10.1089/fpd.2010.0774 | 21,214,381 | D000822:Animal Husbandry; D000818:Animals; D001419:Bacteria; D001483:Base Sequence; D002417:Cattle; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D004197:Disease Reservoirs; D005243:Feces; D008372:Manure; D008969:Molecular Sequence Data; D012336:RNA, Ribosomal, 16S; D017422:Sequence Analysis, DNA; D012988:Soil Microb... | Foodborne pathogens and disease | 2,011 | D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D008372:Manure; D012336:RNA, Ribosomal, 16S |
[Clinical anatomic study of Pitanguy ligament of the nose]. | OBJECTIVE
To observe the origins and insertions of Pitanguy ligament,in order to find the anatomically theoretical basis for the treatment of nasal deformity such as drooping nose, short columella, gingival show.
METHODS
15 cadaveric heads fixed by 10% formalin were used. 12 specimens underwent nasal anatomic study. ... | 24,941,765 | D002102:Cadaver; D002356:Cartilage; D005152:Facial Muscles; D006801:Humans; D008022:Ligaments; D008046:Lip; D009300:Nasal Septum; D009666:Nose; D009667:Nose Deformities, Acquired; D040521:Subcutaneous Tissue | Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery | 2,014 | ||
Socioeconomic status of patients receiving electroconvulsive therapy. | This study describes the relationship between socioeconomic deprivation and electroconvulsive therapy (ECT) prescription and outcomes. Two research questions are addressed in this study: (1) Does the rate of ECT prescription increase with deprivation? and (2) Does deprivation influence ECT outcomes? Electroconvulsive t... | 10.1097/YCT.0b013e31829a01fb | 23,845,939 | D000328:Adult; D000368:Aged; D003866:Depressive Disorder; D004565:Electroconvulsive Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011203:Poverty; D015995:Prevalence; D011320:Primary Health Care; D011569:Psychiatric Status Rating Scales; D012606:Scotland; D012720:Severity of Illness Index;... | The journal of ECT | 2,013 | |
Hypomagnesemia in hemodialysis patients: role of proton pump inhibitors. | BACKGROUND
Recent observations have associated hypomagnesemia with increased risk of cardiovascular morbidity and mortality in hemodialysis patients.
METHODS
We did a 3-month chart review of 62 chronic hemodialysis patients at a single US hospital. All were dialyzed using a dialysate [Mg] of 0.75-1.0 mEq/l. Patients ... | 10.1159/000360011 | 24,577,494 | D000284:Administration, Oral; D000368:Aged; D001639:Bicarbonates; D004573:Electrolytes; D006801:Humans; D016014:Linear Models; D008274:Magnesium; D008297:Male; D008875:Middle Aged; D054328:Proton Pump Inhibitors; D006435:Renal Dialysis; D051437:Renal Insufficiency; D012189:Retrospective Studies; D012306:Risk | American journal of nephrology | 2,014 | D001639:Bicarbonates; D004573:Electrolytes; D054328:Proton Pump Inhibitors; D008274:Magnesium |
Borderline cognitive level in a family with Bazex-Dupré-Christol syndrome. | Bazex-Dupré-Christol syndrome (BDCS) [OMIM 301845] is an X-linked dominant disorder of the hair follicle characterized by multiple basal cell carcinomas, follicular atrophoderma, congenital hypotrichosis, and hypohidrosis. Additional features include multiple milia, trichoepitheliomas, and axillary hidradenitis suppura... | 10.1002/ajmg.a.37041 | 25,820,919 | D000328:Adult; D002280:Carcinoma, Basal Cell; D002648:Child; D002675:Child, Preschool; D003072:Cognition Disorders; D056344:Executive Function; D005260:Female; D006197:Hair; D006801:Humans; D007039:Hypotrichosis; D007558:Italy; D008297:Male; D009483:Neuropsychological Tests; D010375:Pedigree; D010641:Phenotype; D011597... | American journal of medical genetics. Part A | 2,015 | |
[The surgical opportunity in metastatic lesions of renal-cell carcinoma after a response to adjuvant immunotherapy]. | Surgical resection of primary lesions and single metastasis can be curative, but surgery, used as the only therapeutic option, is not unanimously accepted in patients with multiple metastasis and, apart from other considerations, there are no established clinical criteria to allow us to predict which patients will bene... | 8,659,277 | D000368:Aged; D002292:Carcinoma, Renal Cell; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007167:Immunotherapy; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D007376:Interleukin-2; D007680:Kidney Neoplasms; D008175:Lung Neoplasms; D008197:Lymph Node Excision; D00... | Actas urologicas espanolas | 1,995 | D000077190:Interferon alpha-2; D016898:Interferon-alpha; D007376:Interleukin-2; D011994:Recombinant Proteins | |
Shout louder about poor pay. | It seems increasingly clear to me that the NHS pay campaign is not making waves either in the NHS or with the public. | 10.7748/ns.31.13.30.s28 | 27,892,235 | D009740:Nursing Staff; D012456:Salaries and Fringe Benefits; D013222:State Medicine; D006113:United Kingdom | Nursing standard (Royal College of Nursing (Great Britain) : 1987) | 2,016 | |
Rule Encoding in Orbitofrontal Cortex and Striatum Guides Selection. | Active maintenance of rules, like other executive functions, is often thought to be the domain of a discrete executive system. An alternative view is that rule maintenance is a broadly distributed function relying on widespread cortical and subcortical circuits. Tentative evidence supporting this view comes from resear... | 10.1523/JNEUROSCI.1766-16.2016 | 27,807,165 | D000818:Animals; D001288:Attention; D002755:Choice Behavior; D003342:Corpus Striatum; D056344:Executive Function; D007858:Learning; D008253:Macaca mulatta; D008297:Male; D009415:Nerve Net; D017397:Prefrontal Cortex | The Journal of neuroscience : the official journal of the Society for Neuroscience | 2,016 | |
On the frequency of occurrence of a peculiar polyester fibre type found in blue denim textiles. | In a double murder investigation, the victims were found after a prolonged stay in a drainage canal. In spite of the expectations, fibre examination established a multitude of primary and secondary transferred fibres. One of these fibre types was a colourless polyester fibre possessing a blue coloured molten fibre end.... | 10.1016/j.scijus.2011.02.001 | 22,137,048 | Science & justice : journal of the Forensic Science Society | 2,011 | ||
Financial difficulties but not other types of recent negative life events show strong interactions with 5-HTTLPR genotype in the development of depressive symptoms. | Several studies indicate that 5-HTTLPR mediates the effect of childhood adversity in the development of depression, while results are contradictory for recent negative life events. For childhood adversity the interaction with genotype is strongest for sexual abuse, but not for other types of childhood maltreatment; how... | 10.1038/tp.2016.57 | 27,138,797 | D000293:Adolescent; D003866:Depressive Disorder; D005260:Female; D006801:Humans; D006814:Hungary; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic; D012307:Risk Factors; D050486:Serotonin Plasma Membrane Transport Proteins; D012959:Socioeconomic Factors; D013315:Stress, Psych... | Translational psychiatry | 2,016 | C493230:SLC6A4 protein, human; D050486:Serotonin Plasma Membrane Transport Proteins |
Bacterial Microbiota and Fatty Acids in the Faeces of Overweight and Obese Children. | The growing number of children with overweight and obesity constitutes a major health problem of the modern world and it has been suggested that intestinal microbiota may influence energy intake from food. The objectives of this study were to determine quantity and proportions of dominant genera of Bacteroides, Prevote... | 10.21307/pjm-2018-041 | 30,451,451 | D000293:Adolescent; D001419:Bacteria; D041963:Bacteroidetes; D001644:Bifidobacterium; D002648:Child; D064806:Dysbiosis; D005232:Fatty Acids, Volatile; D005243:Feces; D005260:Female; D000068536:Firmicutes; D000069196:Gastrointestinal Microbiome; D006801:Humans; D008297:Male; D009765:Obesity; D050177:Overweight; D012336:... | Polish journal of microbiology | 2,018 | D005232:Fatty Acids, Volatile; D012336:RNA, Ribosomal, 16S |
Benefits of pulmonary rehabilitation in COPD patients with mild cognitive impairment - A pilot study. | BACKGROUND
Cognitive impairment might interfere with the efficacy of Pulmonary Rehabilitation (PR) in Chronic Obstructive Pulmonary Disease (COPD). We aimed to identify differential responses to PR between cognitively impaired (CI) and cognitively normal (CN) COPD patients by assessing health status and exercise capaci... | 10.1016/j.rmed.2021.106478 | 34,038,843 | D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition; D060825:Cognitive Dysfunction; D017079:Exercise Tolerance; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D029424:Pulmonary Disease, Chronic Obstructive; D000070857:Walk Test | Respiratory medicine | 2,021 | |
[Hemangiopericytoma (author's transl)]. | Hemangiopericytoma (HP) is extremely rare in our country. During the last 30 years only two cases were found in the material of our institute. The first case was a tumor of the neck. In spite of little histological evidence of malignancy, local recurrence together with bone metastases occurred four years after removal ... | 7,269,828 | D000368:Aged; D001365:Axilla; D001859:Bone Neoplasms; D005260:Female; D005542:Forearm; D006258:Head and Neck Neoplasms; D006390:Hemangioendothelioma; D006393:Hemangiopericytoma; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012878:Skin Neoplasms | Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie | 1,981 | ||
North Carolina's Transformation to Medicaid Managed Care. | As North Carolina's Medicaid program transitions from fee-for-service to managed care, the Department of Health and Human Services is committed to building an innovative, whole-person-centered and well-coordinated system of care that addresses both medical and non-medical drivers of health. Delivering on that vision, a... | 10.18043/ncm.80.5.277 | 31,471,508 | D006801:Humans; D008329:Managed Care Programs; D008484:Medicaid; D009657:North Carolina; D014481:United States | North Carolina medical journal | 2,019 | |
Farm Hall Transcripts Reconsidered. | The Farm Hall Transcripts appeared to offer a unique opportunity for a study in the history and sociology of science. My request for access to the transcripts was initially denied, but later was allowed thanks to the intervention of British intellectuals. The recorded opinions of the interned German scientists indicate... | 10.1002/bewi.202280104 | 35,680,614 | D001290:Attitude; D000072480:Farms; D009014:Morals; D012961:Sociology | Berichte zur Wissenschaftsgeschichte | 2,022 | |
Parachordoma of the gastric serosa: report of a myxoid mimicry in an unusual location. | The authors report a case of an incidentally discovered myxoid stromal tumor occurring in the outer wall of the stomach of a 65-year-old woman. The tumor was phenotypically consistent with parachordoma (or myoepithelioma), showing a chordoid microscopic appearance of tumor cells loosely arranged within a myxoid or hyal... | 10.1177/1066896907302367 | 17,652,546 | D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D009208:Myoepithelioma; D009418:S100 Proteins; D012704:Serous Membrane; D012983:Soft Tissue Neoplasms; D013274:Stomach Neoplasms; D014746:Vimentin | International journal of surgical pathology | 2,007 | D009418:S100 Proteins; D014746:Vimentin |
International findings with the Achenbach System of Empirically Based Assessment (ASEBA): applications to clinical services, research, and training. | The purpose of this invited article is to present multicultural norms and related international findings obtained with the Achenbach System of Empirically Based Assessment (ASEBA) by indigenous researchers in over 50 societies. The article describes ASEBA instruments for which multicultural norms are available, plus pr... | 10.1186/s13034-019-0291-2 | 31,312,253 | Child and adolescent psychiatry and mental health | 2,019 | ||
XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription. | Nucleotide excision repair is a highly versatile DNA repair system responsible for elimination of a wide variety of lesions from the genome. It is comprised of two subpathways: transcription-coupled repair that accomplishes efficient removal of damage blocking transcription and global genome repair. Recently, the basic... | 10.1074/jbc.M004936200 | 10,944,529 | D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D000818:Animals; D015815:Cell Adhesion Molecules; D002461:Cell Line, Transformed; D004260:DNA Repair; D018076:DNA, Complementary; D004268:DNA-Binding Proteins; D005347:Fibroblasts; D005656:Fungal Proteins; D015723:Gene Library; D005982:Glutathione Transferase; D00... | The Journal of biological chemistry | 2,000 | D015815:Cell Adhesion Molecules; D018076:DNA, Complementary; D004268:DNA-Binding Proteins; D005656:Fungal Proteins; D015800:Protozoan Proteins; D000072260:RNA Splicing Factors; D014157:Transcription Factors; C417244:XAB2 protein, human; C497314:XPA protein, human; D051760:Xeroderma Pigmentosum Group A Protein; C052291:... |
Efficient coupling into tapered proton-exchanged LiNbO(3) waveguides fabricated by vertically controlled immersion. | Planar LiNbO(3) waveguides with a 5-mm tapered region and a 10-mm homogeneous slab waveguide region were fabricated by a double proton-exchange process. The 4-microm waveguide entrance gives rise to a coupling efficiency as high as 93%; the precise control of the depth profile of the tapered region results in a low 1-d... | 10.1364/ol.21.000042 | 19,865,298 | Optics letters | 1,996 | ||
Coordination chemistry of platinum and palladium in the solid-state: synthesis of imidazole and pyrazole complexes. | Solid-state reactions of palladium(II) and platinum(II) chloride complexes with imidazole (Him) and pyrazole (Hpz) or their hydrochloride salts are shown to produce metal complex salts and coordination compounds. Thus, K(2)[MCl(4)] or MCl(2) can be ground with imidazolium chloride ([H(2)im]Cl) to produce the salts [H(2... | 10.1039/b919665j | 20,354,624 | Dalton transactions (Cambridge, England : 2003) | 2,010 | ||
Electrophysiological assessment of the concentration and attention in patient with nasal polyposis. | BACKGROUND
Nasal polyposis is a chronic disease presenting with nasal obstruction as the most frequent complaint. It has been documented that nasal polyposis results in deterioration of quality of life and disturbances of sleep. However, remarkable consequences of nasal polyposis such as psychological and cognitive out... | 10.5415/apallergy.2018.8.e27 | 30,079,305 | Asia Pacific allergy | 2,018 | ||
Transfer of passive immunity from mother to young in a teleost fish: haemagglutinating activity in the serum and eggs of plaice, Pleuronectes platessa L. | Plaice were immunized against rabbit red blood cells (rbc) and the haemagglutinating activity in their sera and eggs was isolated by gel filtration in Sephacryl S300 SF. A "heavy" (greater than 6.69 X 10(5) Daltons) and a "light" (less than 2.32 X 10(5) Daltons) component of haemagglutinating activity were present in p... | 10.1016/0300-9629(86)90620-1 | 2,873,930 | D000818:Animals; D002850:Chromatography, Gel; D004912:Erythrocytes; D005399:Fishes; D006384:Hemagglutination; D006386:Hemagglutination Tests; D006388:Hemagglutinins; D007112:Immunity, Maternally-Acquired; D007122:Immunoelectrophoresis; D007075:Immunoglobulin M; D007136:Immunoglobulins; D010063:Ovum; D011817:Rabbits | Comparative biochemistry and physiology. A, Comparative physiology | 1,986 | D006388:Hemagglutinins; D007075:Immunoglobulin M; D007136:Immunoglobulins |
Understanding sexual offences in UK military and veteran populations: delineating the offences and setting research priorities. | Recent publications have highlighted the need to address inappropriate behaviours, including discrimination, bullying and sexual harassment, within the British Armed Forces; however, no UK work to date pays sufficient attention to sexual offences as defined by the Sexual Offences Act (2003). In trying to ascertain prev... | 10.1136/bmjmilitary-2020-001453 | 32,345,675 | D006801:Humans; D008889:Military Personnel; D012106:Research; D012742:Sex Offenses; D006113:United Kingdom; D014481:United States; D014728:Veterans | BMJ military health | 2,022 | |
Propofol Alone versus Propofol in Combination with Midazolam for Sedative Endoscopy in Patients with Paradoxical Reactions to Midazolam. | BACKGROUND/AIMS
The efficacy of propofol in gastrointestinal endoscopy for patients with midazolam-induced paradoxical reactions remains unclarified. This study aimed to compare the efficacy and safety of propofol-based sedation in patients who previously experienced paradoxical reactions.
METHODS
This was a prospect... | 10.5946/ce.2021.126 | 34,634,857 | Clinical endoscopy | 2,022 | ||
Potential effect of different radiologist reporting methods on studies showing benefit of CAD. | RATIONALE AND OBJECTIVES
To investigate the effect of different reporting methods and performance measures on the assessment of the benefit of computer-aided diagnosis (CAD) in characterizing malignant and benign breast lesions on mammography and sonography.
MATERIALS AND METHODS
In a previous study, 10 observers pro... | 10.1016/j.acra.2007.09.015 | 18,206,613 | D019540:Area Under Curve; D001706:Biopsy; D001943:Breast Neoplasms; D003936:Diagnosis, Computer-Assisted; D004282:Documentation; D006801:Humans; D008327:Mammography; D015588:Observer Variation; D012372:ROC Curve; D012680:Sensitivity and Specificity; D016217:Ultrasonography, Mammary | Academic radiology | 2,008 | |
Predictors of Pediatric COVID-19 vaccination: a case-control study in Tabriz, Iran. | INTRODUCTION
COVID-19 vaccination of children can help reduce the severity of the infection and the death rate caused by it and also helps achieve herd immunity. The level of acceptance and high vaccination coverage is the main elements in the success of immunization programs. Children's vaccination is dependent on the... | 10.1186/s12887-023-04202-y | 37,525,177 | D002648:Child; D006801:Humans; D000293:Adolescent; D000086663:COVID-19 Vaccines; D016022:Case-Control Studies; D007492:Iran; D000086382:COVID-19; D014611:Vaccination; D010290:Parents | BMC pediatrics | 2,023 | D000086663:COVID-19 Vaccines |
Human proopiomelanocortin-(79-96), a proposed cortical androgen-stimulating hormone, does not affect steroidogenesis in cultured human adult adrenal cells. | The existence of a cortical androgen-stimulating hormone (CASH), distinct from ACTH, regulating the secretion of human adrenal androgens has long been postulated. Recently, it has been reported that an 18-amino acid peptide, corresponding to the first part of the joining peptide of proopiomelanocortin [POMC-(79-96)], w... | 10.1210/jcem-72-1-23 | 1,846,004 | D000311:Adrenal Glands; D000324:Adrenocorticotropic Hormone; D000328:Adult; D000595:Amino Acid Sequence; D002478:Cells, Cultured; D003687:Dehydroepiandrosterone; D019314:Dehydroepiandrosterone Sulfate; D006801:Humans; D006854:Hydrocortisone; D008297:Male; D008969:Molecular Sequence Data; D010446:Peptide Fragments; D011... | The Journal of clinical endocrinology and metabolism | 1,991 | D010446:Peptide Fragments; C028182:proopiocortin fragments; D003687:Dehydroepiandrosterone; D019314:Dehydroepiandrosterone Sulfate; D011333:Pro-Opiomelanocortin; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone |
Duodenal adenocarcinoma: Surgical results of 27 patients treated at a single center. | INTRODUCTION
Duodenal adenocarcinoma is a rare malignancy. Given the rarity of the disease, there is limited data related to resection results. The objective is to analyze results at our hospital after the curative resection of duodenal adenocarcinoma (DA).
METHODS
The variables were retrospectively collected from pa... | 10.1016/j.ciresp.2019.06.014 | 31,563,268 | D000230:Adenocarcinoma; D000328:Adult; D000359:Aftercare; D000368:Aged; D000369:Aged, 80 and over; D018572:Disease-Free Survival; D004379:Duodenal Neoplasms; D004386:Duodenum; D005260:Female; D006801:Humans; D008198:Lymph Nodes; D008207:Lymphatic Metastasis; D008297:Male; D000072662:Margins of Excision; D008875:Middle ... | Cirugia espanola | 2,019 | |
Dermatopathologic findings in 20 cases of systemic amyloidosis. | The clinical findings of systemic amyloidosis are often variable and nonspecific. The early recognition of this disorder relies upon clinical suspicion, and definite diagnosis requires the confirmation of amyloid deposits in tissue. We reviewed 31 skin biopsy specimens from 20 patients, including 17 with amyloid light ... | 10.1097/00000372-199810000-00001 | 9,790,101 | D000368:Aged; D000369:Aged, 80 and over; D000682:Amyloid; D000686:Amyloidosis; D001706:Biopsy; D002681:China; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008875:Middle Aged; D000685:Serum Amyloid A Protein; D012867:Skin; D013624:Taiwan | The American Journal of dermatopathology | 1,998 | D000682:Amyloid; D000685:Serum Amyloid A Protein; C035222:amyloid protein AL |
Markers of electrical instability in hypertensive patients with and without ventricular arrhythmias. Are they useful in identifying patients with different risk profiles? | BACKGROUND
Markers of electrical instability of the ventricular myocardium, namely abnormal repolarization and late potentials, are frequently observed in patients with hypertension when both ventricular arrhythmias and left ventricular hypertrophy are present. This information cannot be extrapolated to the population ... | 10.1097/00004872-200018060-00015 | 10,872,562 | D000328:Adult; D005117:Cardiac Complexes, Premature; D004452:Echocardiography; D004562:Electrocardiography; D004594:Electrophysiology; D005260:Female; D006321:Heart; D006801:Humans; D006973:Hypertension; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012307:Risk Factors | Journal of hypertension | 2,000 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.