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MicroRNA-495 inhibits proliferation of glioblastoma multiforme cells by downregulating cyclin-dependent kinase 6. | BACKGROUND
Glioblastoma multiforme (GBM) is the most aggressive type of glioma and carries the poorest chances of survival. There is therefore an urgent need to understand the mechanisms of glioma tumorigenesis and develop or improve therapeutics. The aim of this study was to assess the possible prognostic value of cyc... | 10.1186/1477-7819-11-87 | 23,594,394 | D017209:Apoptosis; D015153:Blotting, Western; D001932:Brain Neoplasms; D059447:Cell Cycle Checkpoints; D049109:Cell Proliferation; D051361:Cyclin-Dependent Kinase 6; D005260:Female; D005500:Follow-Up Studies; D015972:Gene Expression Regulation, Neoplastic; D005909:Glioblastoma; D006801:Humans; D007124:Immunoenzyme Tech... | World journal of surgical oncology | 2,013 | C577768:MIRN495 microRNA, human; D035683:MicroRNAs; D012333:RNA, Messenger; D034741:RNA, Small Interfering; D016160:Retinoblastoma Protein; C495911:CDK6 protein, human; D051361:Cyclin-Dependent Kinase 6 |
Operando monitoring of single-particle kinetic state-of-charge heterogeneities and cracking in high-rate Li-ion anodes. | To rationalize and improve the performance of newly developed high-rate battery electrode materials, it is crucial to understand the ion intercalation and degradation mechanisms occurring during realistic battery operation. Here we apply a laboratory-based operando optical scattering microscopy method to study micromet... | 10.1038/s41563-022-01324-z | 35,970,962 | Nature materials | 2,022 | ||
The business of palliative medicine--Part 2: The economics of acute inpatient palliative medicine. | Economic feasibility is a major factor in the viability of established acute inpatient palliative medicine. Several clinical, administrative, and financial parameters determine the financial health of inpatient care. Financial management metrics include case mix index (CMI) (as determined by the Federal Register as an ... | 10.1177/104990910201900206 | 11,926,450 | D000368:Aged; D005260:Female; D017048:Health Care Costs; D006760:Hospitalization; D006801:Humans; D007902:Length of Stay; D008297:Male; D009820:Ohio; D010166:Palliative Care; D013727:Terminal Care | The American journal of hospice & palliative care | 2,002 | |
The interaction between hydrogel lenses and sodium fluorescein. Theoretical and practical considerations. | The interaction between sodium fluorescein dye and hydrophilic contact lenses was assessed quantitatively by spectrophotometry. Absorption of dye into he lens matrix was found to be proportional to the exposure time and also depends on the optical power and water content of the lens. 0.9% saline appeared preferable to ... | 10.1111/j.1755-3768.1989.tb01630.x | 2,801,049 | D003263:Contact Lenses, Hydrophilic; D004203:Disinfection; D019793:Fluorescein; D005452:Fluoresceins; D008954:Models, Biological | Acta ophthalmologica | 1,989 | D005452:Fluoresceins; D019793:Fluorescein |
The Src-cortactin pathway is required for clustering of E-selectin and ICAM-1 in endothelial cells. | Adhesion molecules such as E-selectin and intercellular adhesion molecule-1 (ICAM-1) expressed on endothelial cells (ECs) at sites of inflammation play an important role in the recruitment of leukocytes from the bloodstream into extravascular tissue. However, little is known about the signaling pathways that are initia... | 10.1096/fj.01-0969fje | 12,060,669 | D002448:Cell Adhesion; D002460:Cell Line; D002478:Cells, Cultured; D051356:Cortactin; D019040:E-Selectin; D004730:Endothelium, Vascular; D006801:Humans; D018799:Intercellular Adhesion Molecule-1; D008840:Microfilament Proteins; D008954:Models, Biological; D010766:Phosphorylation; D019000:Phosphotyrosine; D016392:Proto-... | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2,002 | C495868:CTTN protein, human; D051356:Cortactin; D019040:E-Selectin; D008840:Microfilament Proteins; D018799:Intercellular Adhesion Molecule-1; D019000:Phosphotyrosine; D016392:Proto-Oncogene Proteins pp60(c-src) |
Rabconnectin3α promotes stable activity of the H+ pump on synaptic vesicles in hair cells. | Acidification of synaptic vesicles relies on the vacuolar-type ATPase (V-ATPase) and provides the electrochemical driving force for neurotransmitter exchange. The regulatory mechanisms that ensure assembly of the V-ATPase holoenzyme on synaptic vesicles are unknown. Rabconnectin3α (Rbc3α) is a potential candidate for r... | 10.1523/JNEUROSCI.1705-12.2012 | 22,875,945 | D000161:Acoustic Stimulation; D000200:Action Potentials; D048868:Adaptor Proteins, Signal Transducing; D000704:Analysis of Variance; D000818:Animals; D030801:Animals, Genetically Modified; D004791:Enzyme Inhibitors; D004924:Escape Reaction; D049452:Green Fluorescent Proteins; D006198:Hair Cells, Auditory; D007814:Larva... | The Journal of neuroscience : the official journal of the Society for Neuroscience | 2,012 | D048868:Adaptor Proteins, Signal Transducing; D004791:Enzyme Inhibitors; D018942:Macrolides; D026901:Membrane Transport Proteins; D017494:Proton Pumps; D012333:RNA, Messenger; D029961:Zebrafish Proteins; C057620:bafilomycin A; D049452:Green Fluorescent Proteins; C520788:V-ATPase subunit A, zebrafish; D025262:Vacuolar P... |
[Management of 42 complex intracranial aneurysms in hybrid operating room]. | Objective: To analyze the efficacy and methods of hybrid operation in the treatment of complex intracranial aneurysms. Methods: Fourty-two patients with complex intracranial aneurysms were treated in hybrid operation room of Qilu Hospital of Shandong University between July 2011 and October 2016. Twenty-one cases of an... | 10.3760/cma.j.issn.0376-2491.2017.11.003 | 28,355,733 | D004621:Embolization, Therapeutic; D006801:Humans; D002532:Intracranial Aneurysm; D009873:Operating Rooms; D012008:Recurrence; D016896:Treatment Outcome | Zhonghua yi xue za zhi | 2,017 | |
Capacity Building Using Digital Technology for Occupational Therapists and Caregivers in Pakistan: A Participatory Action Research Approach. | This paper describes the development and implementation of a telehealth system in Pakistan to build capacity of healthcare service providers and caregivers of children with developmental disabilities. An asynchronous telehealth system, in the form of a web app, improved therapy-related communication between the therapi... | 10.5195/ijt.2022.6509 | 38,026,558 | International journal of telerehabilitation | 2,022 | ||
Toxicogenomic effects common to triazole antifungals and conserved between rats and humans. | The triazole antifungals myclobutanil, propiconazole and triadimefon cause varying degrees of hepatic toxicity and disrupt steroid hormone homeostasis in rodent in vivo models. To identify biological pathways consistently modulated across multiple timepoints and various study designs, gene expression profiling was cond... | 10.1016/j.taap.2009.04.016 | 19,409,404 | D000818:Animals; D000935:Antifungal Agents; D004305:Dose-Response Relationship, Drug; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D022781:Hepatocytes; D006801:Humans; D008099:Liver; D008297:Male; D009570:Nitriles; D051381:Rats; D017207:Rats, Sprague-Dawley; D017208:Rats, Wistar; D013045:Speci... | Toxicology and applied pharmacology | 2,009 | D000935:Antifungal Agents; D009570:Nitriles; D014230:Triazoles; C045950:propiconazole; C032910:triadimefon; C446685:systhane |
Optical trapping and manipulation of plasmonic nanoparticles: fundamentals, applications, and perspectives. | This feature article discusses the optical trapping and manipulation of plasmonic nanoparticles, an area of current interest with potential applications in nanofabrication, sensing, analytics, biology and medicine. We give an overview over the basic theoretical concepts relating to optical forces, plasmon resonances an... | 10.1039/c3nr06617g | 24,664,273 | Nanoscale | 2,014 | ||
External pancreatic fistula as a sequel to management of acute severe necrotizing pancreatitis. | BACKGROUND/AIMS
External pancreatic fistula (EPF) is a common sequel to surgical or percutaneous intervention for infective complications of acute severe pancreatitis. The present study was aimed at studying the clinical profile, course and outcome of patients with EPF following surgical or percutaneous management of t... | 10.1159/000091448 | 16,479,114 | D000293:Adolescent; D000328:Adult; D000368:Aged; D017577:Cutaneous Fistula; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010185:Pancreatic Fistula; D010192:Pancreatic Pseudocyst; D019283:Pancreatitis, Acute Necrotizing; D011183:Postoperative Complications; D012189:Retrospective Studies; D013997:T... | Digestive surgery | 2,005 | |
Drug-induced regulation of the MDR1 promoter in Candida albicans. | Resistance of Candida albicans to azole antifungal drugs is mediated by two types of efflux pumps, encoded by the MDR1 gene and the CDR gene family. MDR1 mRNA levels in a susceptible clinical isolate are induced by benomyl (BEN) but not by other drugs previously shown to induce MDR1. To monitor MDR1 expression under se... | 10.1128/AAC.49.7.2785-2792.2005 | 15,980,350 | D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000935:Antifungal Agents; D001542:Benomyl; D015152:Blotting, Northern; D002176:Candida albicans; D004742:Enhancer Elements, Genetic; D015966:Gene Expression Regulation, Fungal; D017930:Genes, Reporter; D008156:Luciferases; D008826:Microbial Sensitivity T... | Antimicrobial agents and chemotherapy | 2,005 | D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000935:Antifungal Agents; D020122:tert-Butylhydroperoxide; D008156:Luciferases; D001542:Benomyl |
Spatiotemporal activation of caspase-dependent and -independent pathways in staurosporine-induced apoptosis of p53wt and p53mt human cervical carcinoma cells. | BACKGROUND INFORMATION
Caspase-dependent and -independent death mechanisms are involved in apoptosis in a variety of human carcinoma cells treated with antineoplastic compounds. Our laboratory has reported that p53 is a key contributor of mitochondrial apoptosis in cervical carcinoma cells after staurosporine exposure.... | 10.1042/BC20080164 | 19,216,720 | D000970:Antineoplastic Agents; D017209:Apoptosis; D002277:Carcinoma; D061945:Caspase Inhibitors; D020169:Caspases; D004789:Enzyme Activation; D005260:Female; D006801:Humans; D009154:Mutation; D015398:Signal Transduction; D019311:Staurosporine; D016159:Tumor Suppressor Protein p53; D002583:Uterine Cervical Neoplasms | Biology of the cell | 2,009 | D000970:Antineoplastic Agents; D061945:Caspase Inhibitors; D016159:Tumor Suppressor Protein p53; D020169:Caspases; D019311:Staurosporine |
Advances and challenges in genetic technologies to produce single-sex litters. | There is currently a requirement for single-sex litters for many applications, including agriculture, pest control, and reducing animal culling in line with the 3Rs principles: Reduction, Replacement, and Refinement. The advent of CRISPR/Cas9 genome editing presents a new opportunity with which to potentially generate ... | 10.1371/journal.pgen.1008898 | 32,701,961 | D000818:Animals; D064113:CRISPR-Cas Systems; D005260:Female; D000072669:Gene Editing; D008297:Male; D012098:Reproduction; D012732:Sex Determination Analysis; D019849:Sex Determination Processes | PLoS genetics | 2,020 | |
Protein connectivity and protein complexity promotes human gene duplicability in a mutually exclusive manner. | It has previously been reported that protein complexity (i.e. number of subunits in a protein complex) is negatively correlated to gene duplicability in yeast as well as in humans. However, unlike in yeast, protein connectivity in a protein-protein interaction network has a positive correlation with gene duplicability ... | 10.1093/dnares/dsq019 | 20,829,394 | D003627:Data Interpretation, Statistical; D019143:Evolution, Molecular; D005656:Fungal Proteins; D020440:Gene Duplication; D016681:Genome, Fungal; D015894:Genome, Human; D042822:Genomic Instability; D057895:Haploinsufficiency; D006801:Humans; D008957:Models, Genetic; D011487:Protein Conformation; D054730:Protein Intera... | DNA research : an international journal for rapid publication of reports on genes and genomes | 2,010 | D005656:Fungal Proteins; D021122:Protein Subunits; D011506:Proteins |
Gender differences in stroke, mortality, and hospitalization among patients with atrial fibrillation: A systematic review. | OBJECTIVE
To conduct a systematic review of gender differences in stroke, mortality, and hospitalization for patients with atrial fibrillation and/or flutter (AF/Afl).
METHODS
Full texts, published, peer-reviewed, English language articles from 1999 through July 2014 were examined. Articles with populations of patien... | 25,703,992 | D001281:Atrial Fibrillation; D001282:Atrial Flutter; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies; D012737:Sex Factors; D020521:Stroke | Heart & lung : the journal of critical care | 2,015 | ||
Bayesian inference for network meta-regression using multivariate random effects with applications to cholesterol lowering drugs. | Low-density lipoprotein cholesterol (LDL-C) has been identified as a causative factor for atherosclerosis and related coronary heart disease, and as the main target for cholesterol- and lipid-lowering therapy. Statin drugs inhibit cholesterol synthesis in the liver and are typically the first line of therapy to lower e... | 10.1093/biostatistics/kxy014 | 29,912,318 | D000924:Anticholesteremic Agents; D001499:Bayes Theorem; D008078:Cholesterol, LDL; D006801:Humans; D006937:Hypercholesterolemia; D015233:Models, Statistical; D000071076:Network Meta-Analysis; D012044:Regression Analysis | Biostatistics (Oxford, England) | 2,019 | D000924:Anticholesteremic Agents; D008078:Cholesterol, LDL |
Two new loci for hybrid sterility in cultivated rice (Oryza sativa L.). | Female gamete abortion in Indica-Japonica crosses of rice was earlier identified to be due to an allelic interaction at the S-5 locus on chromosome 6. Recently, in other crosses of rice, similar allelic interactions were found at loci designated as S-7 and S-8, located on chromosomes 7 and 6 respectively. All of them a... | 10.1007/BF00223375 | 24,166,167 | TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik | 1,996 | ||
Early stage root-Associated fungi show a high temporal turnover, but Are independent of beech progeny. | The relationship between trees and root-associated fungal communities is complex. By specific root deposits and other signal cues, different tree species are able to attract divergent sets of fungal species. Plant intraspecific differences can lead to variable fungal patterns in the root's proximity. Therefore, within ... | 10.3390/microorganisms8020210 | 32,033,191 | Microorganisms | 2,020 | ||
When social anxiety co-occurs with substance use: does an impulsive social anxiety subtype explain this unexpected relationship? | Although most conceptualizations of social anxiety emphasise that socially anxious individuals are overtly shy, and utilise avoidant behavioural strategies (e.g., risk-aversion, passivity, and submissiveness), there is tentative support for the existence of an approach-motivated subtype, characterised by risk taking an... | 25,261,335 | D000293:Adolescent; D000328:Adult; D000368:Aged; D001008:Anxiety Disorders; D015897:Comorbidity; D005260:Female; D006306:Health Surveys; D006801:Humans; D007175:Impulsive Behavior; D007266:Inhibition, Psychological; D008297:Male; D008875:Middle Aged; D010698:Phobic Disorders; D012309:Risk-Taking; D012651:Self Medicatio... | Psychiatry research | 2,014 | ||
[Dimethyl sulfoxide in the treatment of patients with inflammatory diseases of external and middle ear]. | The combination of various drugs with midethyl sulfoxide (DS) solution has been tried in 49 patients with inflammation of the external ear and 10 patients with acute otitis media. It was found that DS solutions potentiate the effect of the drugs. A broad antibacterial and antimycotic spectrum, high transdermal, analget... | 8,009,773 | D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents; D004121:Dimethyl Sulfoxide; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010032:Otitis Externa; D010033:Otitis Media | Vestnik otorinolaringologii | 1,993 | D000900:Anti-Bacterial Agents; D004121:Dimethyl Sulfoxide | |
Physicochemical characterization and water vapor sorption of organic solution advanced spray-dried inhalable trehalose microparticles and nanoparticles for targeted dry powder pulmonary inhalation delivery. | Novel advanced spray-dried inhalable trehalose microparticulate/nanoparticulate powders with low water content were successfully produced by organic solution advanced spray drying from dilute solution under various spray-drying conditions. Laser diffraction was used to determine the volumetric particle size and size di... | 10.1208/s12249-011-9704-0 | 22,038,473 | D000280:Administration, Inhalation; D001718:Birefringence; D002152:Calorimetry, Differential Scanning; D002626:Chemistry, Pharmaceutical; D018360:Crystallography, X-Ray; D004337:Drug Carriers; D004339:Drug Compounding; D006358:Hot Temperature; D008855:Microscopy, Electron, Scanning; D008859:Microscopy, Polarization; D0... | AAPS PharmSciTech | 2,011 | D004337:Drug Carriers; D004364:Pharmaceutical Preparations; D011208:Powders; D014867:Water; D014199:Trehalose |
Preparation of monoclonal antibody and identification of two novel B cell epitopes to VP1 protein of porcine sapelovirus. | Porcine sapelovirus (PSV) is an important emerging swine pathogen that causes diarrhoea, respiratory distress, severe reproductive system and neurological disorders in pigs, posing huge threat to swine industry. However, there are no effective serological diagnostic products and the epitope characterization of PSV VP1 ... | 10.1016/j.vetmic.2022.109593 | 36,323,175 | D000818:Animals; D051379:Mice; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D018985:Epitopes, B-Lymphocyte; D007074:Immunoglobulin G; D008807:Mice, Inbred BALB C; D010849:Picornaviridae; D013552:Swine; D014764:Viral Proteins | Veterinary microbiology | 2,022 | D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D018985:Epitopes, B-Lymphocyte; D007074:Immunoglobulin G; D014764:Viral Proteins |
A case of congenital warfarin syndrome due to maternal drug administration during the pregnancy. | Warfarin, which is used for anticoagulant therapy, rarely produces congenital warfarin syndrome characterized with hypoplastic nose, stippled epiphyses, and skeletal abnormalities when ingested during pregnancy. Here, we present a male infant, whose mother was treated with warfarin because of a prosthetic heart valve r... | 21,848,016 | D000014:Abnormalities, Drug-Induced; D000015:Abnormalities, Multiple; D000925:Anticoagulants; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009035:Mothers; D009295:Nasal Bone; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D014859:Warfarin | Genetic counseling (Geneva, Switzerland) | 2,011 | D000925:Anticoagulants; D014859:Warfarin | |
Can anthropomorphic analyses of separation cries in other animals inform us about the emotional nature of social loss in humans? Comment on Blumberg and Sokoloff (2001). | M. S. Blumberg and G. Sokoloff's (2001) critical analysis has raised doubt whether emotional feelings can be studied in nonhuman animals, and they have reaffirmed the inappropriateness of anthropomorphic reasoning in animal research. They argue that the ultrasonic distress calls of infant rats may be little more than a... | 10.1037/0033-295x.110.2.376 | 12,747,529 | D000339:Affect; D000818:Animals; D001010:Anxiety, Separation; D003448:Crying; D006801:Humans; D012938:Social Perception; D014828:Vocalization, Animal | Psychological review | 2,003 | |
Cytoplasmic CREB alpha-like antigens in specific regions of the rat brain. | We have investigated the expression of the alpha-region of CREB (amino acids 88-101) in the rat brain. This region is encoded by a separate exon and has been reported to enhance the transcriptional efficiency of CREB. Light microscopic immunohistochemistry showed labeled neurons in several brain regions, such as the sp... | 10.1006/bbrc.1996.1163 | 8,769,127 | D000818:Animals; D000906:Antibodies; D001369:Axons; D001921:Brain; D002467:Cell Nucleus; D017362:Cyclic AMP Response Element-Binding Protein; D003593:Cytoplasm; D004591:Electrophoresis, Polyacrylamide Gel; D006056:Golgi Apparatus; D015151:Immunoblotting; D008297:Male; D016253:Microscopy, Immunoelectron; D008970:Molecul... | Biochemical and biophysical research communications | 1,996 | D000906:Antibodies; D017362:Cyclic AMP Response Element-Binding Protein |
Potential implications of the objectification of women's bodies for women's sexual satisfaction. | The present study tested a sociocultural model of women's sexual satisfaction grounded in Objectification Theory (Fredrickson & Roberts, 1997). One hundred and one college women attending university in the UK completed measures of media internalization, body surveillance, body shame, sexual self-esteem, and sexual sati... | 10.1016/j.bodyim.2009.01.001 | 19,233,750 | D000293:Adolescent; D000328:Adult; D001828:Body Image; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008402:Mass Media; D010549:Personal Satisfaction; D012649:Self Concept; D019529:Sexuality; D012752:Shame; D011795:Surveys and Questionnaires; D055815:Young Adult | Body image | 2,009 | |
Characterization of the gene cluster for biosynthesis of macrocyclic trichothecenes in Myrothecium roridum. | Macrocyclic trichothecenes are toxic sesquiterpenoids that are produced by certain fungi and plants. The unique structural features of macrocyclic trichothecenes result in increased toxicity relative to other trichothecene structural types. Here we report the sequences and relative locations of the MRTRI5, MRTRI6, and ... | 10.1007/s004380050666 | 9,529,523 | D000595:Amino Acid Sequence; D019755:Carbon-Carbon Lyases; D002874:Chromosome Mapping; D015825:Chromosomes, Fungal; D003001:Cloning, Molecular; D016384:Consensus Sequence; D003360:Cosmids; D003577:Cytochrome P-450 Enzyme System; D005656:Fungal Proteins; D005670:Fusarium; D005800:Genes, Fungal; D005816:Genetic Complemen... | Molecular & general genetics : MGG | 1,998 | D005656:Fungal Proteins; C111503:TRI6 protein, Myrothecium roridum; D014157:Transcription Factors; D014255:Trichothecenes; D003577:Cytochrome P-450 Enzyme System; D010105:Oxygenases; C111502:MRTR14 protein, Myrothecium roridum; D019755:Carbon-Carbon Lyases; C051130:trichodiene synthetase |
Benchmarking in pathology: development of an activity-based costing model. | AIMS
Benchmarking in Pathology (BiP) allows pathology laboratories to determine the unit cost of all laboratory tests and procedures, and also provides organisational productivity indices allowing comparisons of performance with other BiP participants. We describe 14 years of progressive enhancement to a BiP program, i... | 10.1097/PAT.0b013e32835a9ec4 | 23,149,379 | D019985:Benchmarking; D003365:Costs and Cost Analysis; D003695:Delivery of Health Care; D017598:Efficiency, Organizational; D006801:Humans; D007753:Laboratories; D018803:Models, Economic; D010338:Pathology, Clinical | Pathology | 2,012 | |
Effects of treatment for hypertension on cerebral haemorrhage and infarction. | One hundred and sixty nine patients admitted to hospital for stroke over 30 months were examined to see whether treating hypertension had influenced the incidence of cerebral haemorrhage and infarction. Seventy eight (46%) of them had normal blood pressure, 47 (28%) previously diagnosed hypertension for which they were... | 10.1136/bmj.289.6438.156 | 6,430,391 | D000368:Aged; D002543:Cerebral Hemorrhage; D002544:Cerebral Infarction; D005260:Female; D006801:Humans; D006973:Hypertension; D008297:Male; D008875:Middle Aged | British medical journal (Clinical research ed.) | 1,984 | |
Experimental ileitis in dogs and colitis in rats with trinitrobenzene sulfonic acid--colonoscopic and histopathologic studies. | Using a novel experimental model of chronic enterocolitis described by Morris et al., we observed sequential changes of mucosal lesions endoscopically and performed histopathological studies. Fisher rats were rectally administered 25 mg of trinitrobenzene sulfonic acid (TNBS) dissolved in 0.5 ml of 50% ethanol (ET). Th... | 10.1007/BF02776950 | 8,375,625 | D000818:Animals; D003092:Colitis; D003106:Colon; D003113:Colonoscopy; D004285:Dogs; D000431:Ethanol; D007079:Ileitis; D007082:Ileum; D007413:Intestinal Mucosa; D008297:Male; D051381:Rats; D014302:Trinitrobenzenesulfonic Acid | Gastroenterologia Japonica | 1,993 | D000431:Ethanol; D014302:Trinitrobenzenesulfonic Acid |
Insect-resistant transgenic plants in a multi-trophic context. | So far, genetic engineering of plants in the context of insect pest control has involved insertion of genes that code for toxins, and may be characterized as the incorporation of biopesticides into classical plant breeding. In the context of pesticide usage in pest control, natural enemies of herbivores have received i... | 10.1046/j.1365-313x.2002.01366.x | 12,182,699 | D000818:Animals; D001181:Arthropods; D001427:Bacterial Toxins; D020387:Food Chain; D006790:Host-Parasite Interactions; D007113:Immunity, Innate; D007313:Insecta; D007306:Insecticides; D010572:Pest Control, Biological; D010935:Plant Diseases; D030821:Plants, Genetically Modified; D013025:Glycine max | The Plant journal : for cell and molecular biology | 2,002 | D001427:Bacterial Toxins; D007306:Insecticides |
Chili pepper consumption and gastric cancer in Mexico: a case-control study. | Laboratory studies indicate that capsaicin, the hot-tasting component of chili peppers, may be carcinogenic. A population-based case-control study was conducted in Mexico City during 1989-1990 to evaluate the relation between chili pepper consumption and gastric cancer risk. The study included 220 incident cases and 75... | 10.1093/oxfordjournals.aje.a116993 | 8,116,601 | D000230:Adenocarcinoma; D000328:Adult; D002211:Capsaicin; D016022:Case-Control Studies; D016001:Confidence Intervals; D004032:Diet; D004034:Diet Surveys; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D011159:Population Surveillance;... | American journal of epidemiology | 1,994 | D002211:Capsaicin |
Partial susceptibility of the SSN-1 fish cell line to a crustacean virus: a defective replication study. | This study evaluated the possible use of the fish SSN-1 cell line to investigate the development of Macrobrachium rosenbergii nodavirus (MrNV). Cells were incubated with viral particles and cytopathic effects were observed. De novo synthesis of viral capsid proteins was shown by immuno-fluorescence labelling and a sand... | 10.1111/j.1365-2761.2007.00852.x | 17,958,611 | D000818:Animals; D000914:Antibodies, Viral; D000956:Antigens, Viral; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D004797:Enzyme-Linked Immunosorbent Assay; D016679:Genome, Viral; D008856:Microscopy, Fluorescence; D030381:Nodaviridae; D033541:Palaemonidae; D010473:Perciformes; D020133:Reverse Transcriptase ... | Journal of fish diseases | 2,007 | D000914:Antibodies, Viral; D000956:Antigens, Viral; D014764:Viral Proteins |
The in vitro antioxidant and antimicrobial activities of the essential oil and methanol extracts of Achillea biebersteini Afan. (Asteraceae). | The essential oil and methanol extracts from A. biebersteinii Afan. (Asteraceae) were evaluated for their antimicrobial and antioxidant activities in vitro. The oil showed stronger antimicrobial activity than the extracts. Their antioxidant features were also evaluated using diphenyl-1-picrylhydrazyl (DPPH), inhibition... | 10.1002/ptr.1438 | 15,287,068 | D031162:Achillea; D000900:Anti-Bacterial Agents; D000975:Antioxidants; D001713:Biphenyl Compounds; D006090:Gram-Negative Bacteria; D006094:Gram-Positive Bacteria; D006801:Humans; D015227:Lipid Peroxidation; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D010851:Picrates; D010936:Plant Extracts; D010938:Plan... | Phytotherapy research : PTR | 2,004 | D000900:Anti-Bacterial Agents; D000975:Antioxidants; D001713:Biphenyl Compounds; D010851:Picrates; D010936:Plant Extracts; D010938:Plant Oils; C004931:1,1-diphenyl-2-picrylhydrazyl |
BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells. | Most forms of chemotherapy employ mechanisms involving induction of oxidative stress, a strategy that can be effective due to the elevated oxidative state commonly observed in cancer cells. However, recent studies have shown that relative redox levels in primary tumors can be heterogeneous, suggesting that regimens dep... | 23,333,149 | D017209:Apoptosis; D006801:Humans; D007211:Indoles; D015470:Leukemia, Myeloid, Acute; D014411:Neoplastic Stem Cells; D010085:Oxidative Phosphorylation; D019253:Proto-Oncogene Proteins c-bcl-2; D011758:Pyrroles; D017382:Reactive Oxygen Species; D014407:Tumor Cells, Cultured | Cell stem cell | 2,013 | D007211:Indoles; D019253:Proto-Oncogene Proteins c-bcl-2; D011758:Pyrroles; D017382:Reactive Oxygen Species; C520962:obatoclax | |
Brain volume and fatigue in patients with postpoliomyelitis syndrome. | BACKGROUND
Acute paralytic poliomyelitis is associated with encephalitis. Early brain inflammation may produce permanent neuronal injury with brain atrophy, which may result in symptoms such as fatigue. Brain volume has not been assessed in postpoliomyelitis syndrome (PPS).
OBJECTIVE
To determine whether brain volume... | 24,060,387 | D001921:Brain; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D018450:Disease Progression; D004576:Electromyography; D005221:Fatigue; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009103:Multiple S... | PM & R : the journal of injury, function, and rehabilitation | 2,014 | ||
Laser-Direct Writing of Silver Metal Electrodes on Transparent Flexible Substrates with High-Bonding Strength. | We demonstrate a novel approach to rapidly fabricate conductive silver electrodes on transparent flexible substrates with high-bonding strength by laser-direct writing. A new type of silver ink composed of silver nitrate, sodium citrate, and polyvinylpyrrolidone (PVP) was prepared in this work. The role of PVP was eluc... | 10.1021/acsami.6b07696 | 27,560,607 | ACS applied materials & interfaces | 2,016 | ||
Postoperative sedation with midazolam in heart surgery patients: pharmacokinetic considerations. | Midazolam remains one of the few drugs that can safely be used for the sedation of intubated patients in an intensive care unit. Midazolam pharmacokinetics in patients recovering from cardiac surgery were recently reported and found to be different from the drug's kinetics in young and healthy patients or volunteers. I... | 10.1111/j.1399-6576.1990.tb03195.x | 2,183,536 | D000762:Anesthesia Recovery Period; D006348:Cardiac Surgical Procedures; D006207:Half-Life; D006801:Humans; D008874:Midazolam; D011184:Postoperative Period | Acta anaesthesiologica Scandinavica. Supplementum | 1,990 | D008874:Midazolam |
Characteristics of ovine articular chondrocytes in a three-dimensional matrix consisting of different crosslinked collagen. | The purpose of this study was to evaluate the (ultra-) morphology, biochemical behavior, and activity of ovine chondrocytes seeded on a matrix consisting of three types of collagen (I, II, III) with two different degrees of UV crosslinking. Ovine articular chondrocytes were isolated from stifle joints and seeded on bot... | 10.1002/jbm.b.30115 | 15,384,074 | D000818:Animals; D048430:Cell Shape; D002478:Cells, Cultured; D019902:Chondrocytes; D003094:Collagen; D005109:Extracellular Matrix; D015870:Gene Expression; D006025:Glycosaminoglycans; D008855:Microscopy, Electron, Scanning; D016062:Porosity; D012333:RNA, Messenger; D012756:Sheep | Journal of biomedical materials research. Part B, Applied biomaterials | 2,005 | D006025:Glycosaminoglycans; D012333:RNA, Messenger; D003094:Collagen |
Hemodynamic responses to tracheal intubation with the Glidescope videolaryngoscope: a comparison of oral and nasal routes. | BACKGROUND
Although there have been numerous favorable reports on the uses of the GlideScope videolaryngoscope (GSVL) in oral and nasal intubations, no study has compared the hemodynamic responses to oral and nasal intubations with the GSVL in a single clinical trial. The purpose of this randomized clinical study was t... | 10.1016/s1875-4597(08)60014-4 | 18,390,395 | D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D007442:Intubation, Intratracheal; D020704:Laryngoscopes; D008297:Male; D008875:Middle Aged; D012032:Refractory Period, Electrophysiological; D014741:Video Recording | Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists | 2,008 | |
Application of the Taguchi Method for Optimizing the Process Parameters of Producing Lightweight Aggregates by Incorporating Tile Grinding Sludge with Reservoir Sediments. | This study aimed to apply the Taguchi optimization technique to determine the process conditions for producing synthetic lightweight aggregate (LWA) by incorporating tile grinding sludge powder with reservoir sediments. An orthogonal array L16(4⁵) was adopted, which consisted of five controllable four-level factors (i.... | 10.3390/ma10111294 | 29,125,576 | Materials (Basel, Switzerland) | 2,017 | ||
Safety and efficacy of trivalent inactivated influenza vaccine in young children: a summary for the new era of routine vaccination. | Increasing use of influenza vaccine in children is expected as this important virus becomes more widely recognized as a major cause of morbidity in young children. Clinicians and third party payers must consider the implications of national vaccine use recommendations, with their current focus on young children, on the... | 10.1097/01.inf.0000116292.46143.d6 | 15,014,289 | D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007252:Influenza Vaccines; D007251:Influenza, Human; D016032:Randomized Controlled Trials as Topic; D014613:Vaccines, Attenuated; D015164:Vaccines, Inactivated | The Pediatric infectious disease journal | 2,004 | D007252:Influenza Vaccines; D014613:Vaccines, Attenuated; D015164:Vaccines, Inactivated |
Diastolic-systolic velocity ratio to detect coronary stenoses under physiological resting conditions: a mechanistic study. | Objective
Diastolic-systolic velocity ratio (DSVR) is a resting index to assess stenoses in the left anterior descending artery (LAD). DSVR can be measured by echocardiographic or intracoronary Doppler flow velocity. The objective of this cohort study was to elucidate the fundamental rationale underlying the decreased ... | 10.1136/openhrt-2018-000968 | 30,997,134 | Open heart | 2,019 | ||
A systematic review of cognitive function in patients with glioblastoma undergoing surgery. | BACKGROUND
Patients with glioblastoma (GB) are more likely to suffer cognitive deficits with poor quality of life as compared with lower-grade glioma patient groups, for whom cognition research is plentiful. The objective of this systematic review is to evaluate the cognitive function of patients with GB before and aft... | 10.1093/nop/npz018 | 32,626,582 | Neuro-oncology practice | 2,020 | ||
Effect of ionic strength on the adsorption of copper and chromium ions by vermiculite pure clay mineral. | It is important to assess the effects of ionic strength when studying adsorption of metal ions on clay mineral because the background salt may complex metals and compete for adsorption sites. The sorption behavior of vermiculite pure clay mineral has been studied with respect to copper and chromium as a function of ion... | 10.1016/j.jhazmat.2009.05.100 | 19,524,366 | D000327:Adsorption; D000538:Aluminum Silicates; D000643:Ammonium Chloride; D002857:Chromium; D003300:Copper; D011189:Potassium Chloride; D012965:Sodium Chloride; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet; D013816:Thermodynamics | Journal of hazardous materials | 2,009 | D000538:Aluminum Silicates; D012996:Solutions; D000643:Ammonium Chloride; D002857:Chromium; C003760:vermiculite; D012965:Sodium Chloride; D011189:Potassium Chloride; D003300:Copper |
Knowledge and Myths about Palliative Care among the General Public and Health Care Professionals in Portugal. | Background: International research has shown that healthcare professionals (HCPs) and nonhealthcare professionals (NHCPs) are unaware of the goals and purposes of palliative care. This study evaluates the knowledge of palliative care among a sample of Portuguese adults and correlates their level of knowledge with age, ... | 10.3390/ijerph17134630 | 32,605,086 | D000328:Adult; D000368:Aged; D001291:Attitude of Health Personnel; D003430:Cross-Sectional Studies; D005260:Female; D006282:Health Personnel; D006801:Humans; D008297:Male; D010166:Palliative Care; D011174:Portugal; D055815:Young Adult | International journal of environmental research and public health | 2,020 | |
Icon arrays reduce concern over COVID-19 vaccine side effects: a randomized control study. | On April 13, 2021, the CDC announced that the administration of Johnson and Johnson's COVID-19 vaccine would be paused due to a rare blood clotting side effect in ~ 0.0001% of people given the vaccine. Most people who are hesitant to get a COVID-19 vaccine list potential side effects as their main concern (PEW, 2021); ... | 10.1186/s41235-022-00387-5 | 35,524,896 | D000086382:COVID-19; D000086663:COVID-19 Vaccines; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D000086402:SARS-CoV-2; D011795:Surveys and Questionnaires; D014481:United States; D014612:Vaccines | Cognitive research: principles and implications | 2,022 | D000086663:COVID-19 Vaccines; D014612:Vaccines |
Plant-Produced Anti-Zika Virus Monoclonal Antibody Glycovariant Exhibits Abrogated Antibody-Dependent Enhancement of Infection. | Monoclonal antibodies (mAb) against the envelope (E) protein of Zika virus (ZIKV) have shown great potential as therapeutics against the Zika epidemics. However, their use as a therapy may predispose treated individuals to severe infection by the related dengue virus (DENV) via antibody-dependent enhancement of infecti... | 10.3390/vaccines11040755 | 37,112,665 | Vaccines | 2,023 | ||
Suzuki-type Pd(0) coupling reactions in the synthesis of 2-arylpurines as Cdk inhibitors. | A new series of 2-aryl-substituted purine derivatives has been synthesized by Suzuki Pd(0) coupling reactions. Moderate in vitro inhibitory activity against Cdk1 and Cdk5 was observed. These compounds are inactive against GSK3. | 10.1016/j.bmcl.2006.03.060 | 16,616,489 | D016203:CDC2 Protein Kinase; D051360:Cyclin-Dependent Kinase 5; D038362:Glycogen Synthase Kinase 3; D015394:Molecular Structure; D047428:Protein Kinase Inhibitors; D011687:Purines | Bioorganic & medicinal chemistry letters | 2,006 | D047428:Protein Kinase Inhibitors; D011687:Purines; D051360:Cyclin-Dependent Kinase 5; D016203:CDC2 Protein Kinase; D038362:Glycogen Synthase Kinase 3; C030985:purine |
Sialoblastoma: A literature review from 1966-2011. | Sialoblastoma is a rare congenital tumour of the salivary glands arising mainly from the parotid gland. It is usually diagnosed at birth or shortly thereafter with a significant variability in histological appearance and clinical course. In extensive search of PubMed indexed journals, we got 46 cases of "sialobalstoma/... | 10.4103/0975-5950.117821 | 24,163,547 | National journal of maxillofacial surgery | 2,013 | ||
Effect of thoracoabdominal breathing patterns on inspiratory effort sensation. | The respiratory sensations evoked by added inspiratory loads are currently thought to be largely mediated by the activity of the inspiratory muscles. Because of the differences in proprioceptors and in afferent and efferent innervations among the inspiratory muscles, we hypothesized that the sensation evoked by a given... | 10.1152/jappl.1987.62.4.1665 | 3,597,238 | D000005:Abdomen; D000328:Adult; D006801:Humans; D008297:Male; D012119:Respiration; D012677:Sensation; D013909:Thorax; D014939:Work of Breathing | Journal of applied physiology (Bethesda, Md. : 1985) | 1,987 | |
Categorical Variables in Multiple Regression: Some Cautions. | Various methods of coding categorical variables for use as predictors in multiple regression analyses have been presented in the literature. The limitations of two oft-discussed methods -- dummy coding and nonsense coding -- are detailed for several frequently-used regression designs. Two examples involving potentially... | 10.1207/s15327906mbr2302_7 | 26,764,948 | Multivariate behavioral research | 1,988 | ||
Network- and enrichment-based inference of phenotypes and targets from large-scale disease maps. | Complex diseases are inherently multifaceted, and the associated data are often heterogeneous, making linking interactions across genes, metabolites, RNA, proteins, cellular functions, and clinically relevant phenotypes a high-priority challenge. Disease maps have emerged as knowledge bases that capture molecular inter... | 10.1038/s41540-022-00222-z | 35,473,910 | D010641:Phenotype; D011506:Proteins | NPJ systems biology and applications | 2,022 | D011506:Proteins |
Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction. | UDP-glucuronic acid is converted to UDP-galacturonic acid en route to a variety of sugar-containing metabolites. This reaction is performed by a NAD+-dependent epimerase belonging to the short-chain dehydrogenase/reductase family. We present several high-resolution crystal structures of the UDP-glucuronic acid epimeras... | 10.1074/jbc.RA120.014692 | 32,661,196 | D001409:Bacillus cereus; D001426:Bacterial Proteins; D002238:Carbohydrate Epimerases; D018360:Crystallography, X-Ray; D008024:Ligands; D009243:NAD; D010084:Oxidation-Reduction; D012399:Rotation; D014539:Uridine Diphosphate Sugars | The Journal of biological chemistry | 2,020 | D001426:Bacterial Proteins; D008024:Ligands; D014539:Uridine Diphosphate Sugars; D009243:NAD; D002238:Carbohydrate Epimerases |
Mixed type TAPVR-Measure twice, cut once. | Total anomalous pulmonary venous return (TAVR) can have varying drainage configurations. Here, we review a report by Nagulakonda et al. to the Journal of Cardiac Surgery detailing how additional computed tomography imaging revealed a mixed type presentation of TAPVR not identified on echocardiography. | 10.1111/jocs.15632 | 34,061,393 | D004452:Echocardiography; D006330:Heart Defects, Congenital; D006801:Humans; D011667:Pulmonary Veins; D012587:Scimitar Syndrome | Journal of cardiac surgery | 2,021 | |
Poloxamer/cyclodextrin/chitosan-based thermoreversible gel for intranasal delivery of fexofenadine hydrochloride. | To enhance permeation and solubility of an intranasal delivery system of fexofenadine hydrochloride (FXD HCl), a new formulation using poloxamer 407 (P407)/hydroxypropyl-β-cyclodextrin (HP-β-CD)-based thermoreversible gels with chitosan, was developed. Prepared gels were characterized by gelation temperature, viscosity... | 10.1002/jps.22314 | 20,803,575 | D000073738:2-Hydroxypropyl-beta-cyclodextrin; D000281:Administration, Intranasal; D000818:Animals; D002463:Cell Membrane Permeability; D002478:Cells, Cultured; D048271:Chitosan; D005782:Gels; D039563:Histamine H1 Antagonists, Non-Sedating; D006801:Humans; D020442:Poloxamer; D011817:Rabbits; D013696:Temperature; D016593... | Journal of pharmaceutical sciences | 2,011 | D005782:Gels; D039563:Histamine H1 Antagonists, Non-Sedating; D047392:beta-Cyclodextrins; D020442:Poloxamer; D000073738:2-Hydroxypropyl-beta-cyclodextrin; D016593:Terfenadine; D048271:Chitosan; C093230:fexofenadine |
Malignant melanoma and its stromal nonimmune microecosystem. | In recent years, rapid advances were reached in the understanding of a series of biologic signals influencing cutaneous malignant melanoma (CMM) cells. CMM is in close contact with a peculiar dermal extracellular matrix (ECM). Stromal cells store and release various structural ECM components. The impact on CMM growth a... | 10.1155/2012/584219 | 22,811,710 | Journal of oncology | 2,012 | ||
Adenovirus evasion of interferon-mediated innate immunity by direct antagonism of a cellular histone posttranslational modification. | Overcoming the cellular type I interferon (IFN) host defense response is critical for a virus to ensure successful infection. Investigating the effects of human adenovirus (HAdV) infection on global cellular histone posttranslational modification (hPTM), we discovered that virus infection-induced activation of IFN sign... | 10.1016/j.chom.2012.05.005 | 22,704,620 | D017500:Adenovirus E1A Proteins; D000260:Adenoviruses, Human; D006657:Histones; D006801:Humans; D057131:Immune Evasion; D007113:Immunity, Innate; D007372:Interferons; D011499:Protein Processing, Post-Translational; D025801:Ubiquitin; D044767:Ubiquitin-Protein Ligases; D054875:Ubiquitination | Cell host & microbe | 2,012 | D017500:Adenovirus E1A Proteins; D006657:Histones; D025801:Ubiquitin; D007372:Interferons; C506646:RNF20 protein, human; D044767:Ubiquitin-Protein Ligases |
High HIV prevalence predicts less HIV stigma: a cross-national investigation. | Despite substantial global efforts to reduce HIV-related stigma, stigma and discrimination remain widespread and are among the most poorly understood aspects of the epidemic. However, there has been little research on whether HIV stigma in a country is associated with HIV prevalence. This article offers a socioecologic... | 10.1080/09540121.2017.1401039 | 29,129,116 | D000328:Adult; D005260:Female; D014943:Global Health; D015658:HIV Infections; D015528:HIV Seroprevalence; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D057545:Social Stigma; D013240:Stereotyping; D011795:Surveys and Questionnaires | AIDS care | 2,018 | |
Excitatory and inhibitory effects of adenosine on the neurotransmission in the hippocampal slices of guinea pig. | Postsynaptic potentials (PSPs) were recorded from the granular cell layer of guinea pig hippocampal slices. Application of adenosine at a concentration of more than 10 microM in the incubation medium depressed the amplitude of the PSP, but adenosine at a concentration of 10 nM to 1 microM enhanced the amplitude of the ... | 10.1016/0006-8993(90)91335-e | 2,173,961 | D000241:Adenosine; D000818:Animals; D005071:Evoked Potentials; D006168:Guinea Pigs; D006624:Hippocampus; D066298:In Vitro Techniques; D009435:Synaptic Transmission | Brain research | 1,990 | D000241:Adenosine |
Cataract, Alzheimer's disease, and other conformational diseases. | Unfolding of proteins was shown to occur in human cataract more than 25 years ago. Recently, the term conformational diseases was applied to a whole group of diseases in which unfolded or misfolded proteins accumulate. In this article, common features in the biochemistry and epidemiology of cataract, Alzheimer's diseas... | 10.1097/00055735-199802000-00003 | 10,178,625 | D000368:Aged; D000375:Aging; D000544:Alzheimer Disease; D016229:Amyloid beta-Peptides; D000686:Amyloidosis; D002386:Cataract; D006801:Humans; D007908:Lens, Crystalline; D016875:tau Proteins | Current opinion in ophthalmology | 1,998 | D016229:Amyloid beta-Peptides; D016875:tau Proteins |
Two eggs, two different constraints: a potential explanation for the puzzling intraclutch egg size dimorphism in Eudyptes penguins. | Phenotypic plasticity and phenotypic stability are major components of the adaptive evolution of organisms to environmental variation. The invariant two-egg clutch size of Eudyptes penguins has recently been proposed to be a unique example of a maladaptive phenotypic stability, while their egg mass is a plastic trait. ... | 10.1002/ece3.1543 | 26,306,169 | Ecology and evolution | 2,015 | ||
Telavancin, a new lipoglycopeptide antimicrobial, in complicated skin and soft tissue infections. | Telavancin, a novel lipoglycopeptide with rapid concentration-dependent bactericidal effects, is a semisynthetic derivative of the glycopeptide, vancomycin. Telavancin has a dual mechanism of action, ie, inhibition of peptidoglycan polymerization and disruption of the bacterial membrane. It has linear pharmacokinetics,... | 10.2147/IDR.S5327 | 21,694,912 | Infection and drug resistance | 2,011 | ||
Stimulatory effect of insulin and insulin-like growth factor I on Gi proteins and angiotensin-II-induced phosphoinositide breakdown in cultured bovine adrenal cells. | Recent data have shown that pretreatment of bovine adrenal fasciculata cells with insulin-like growth factor I (IGF-I) or insulin enhances the steroidogenic response to angiotensin II (A-II). In the present work we have studied the effects of both peptides on the first steps of the mechanism of action of A-II and on th... | 10.1210/endo-126-4-1867 | 2,156,669 | D000311:Adrenal Glands; D000324:Adrenocorticotropic Hormone; D000804:Angiotensin II; D000818:Animals; D002118:Calcium; D002417:Cattle; D002478:Cells, Cultured; D000242:Cyclic AMP; D004357:Drug Synergism; D019204:GTP-Binding Proteins; D007328:Insulin; D007334:Insulin-Like Growth Factor I; D037342:Pertussis Toxin; D01071... | Endocrinology | 1,990 | D007328:Insulin; D010716:Phosphatidylinositols; D013002:Somatomedins; D010566:Virulence Factors, Bordetella; D000804:Angiotensin II; D007334:Insulin-Like Growth Factor I; D000324:Adrenocorticotropic Hormone; D000242:Cyclic AMP; D037342:Pertussis Toxin; D019204:GTP-Binding Proteins; D002118:Calcium |
Insight in microcirculation and histomorphology during burn shock treatment using in vivo confocal-laser-scanning microscopy. | PURPOSE
Microcirculatory disturbances are well known during shock; however, the accompanied histomorphological alterations are widely unknown. We used high resolution confocal-laser-scanning microscopy for the evaluation of microcirculation and histomorphology during Burn Shock treatment.
METHODS
Confocal-laser-scann... | 10.1016/j.jcrc.2009.03.003 | 19,427,756 | D000328:Adult; D001783:Blood Flow Velocity; D002056:Burns; D016022:Case-Control Studies; D048429:Cell Size; D003422:Critical Care; D005260:Female; D005440:Fluid Therapy; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008833:Microcirculation; D018613:Microscopy, Confocal; D012774:Shock, Traumatic; D012867:Skin; D0... | Journal of critical care | 2,010 | |
Soft tissue molding technique in cleft lip and palate patient using laser surgery in combination with orthodontic appliance: A case report. | BACKGROUND
Although surgical treatment protocols for cleft lip and palate patients have been established, many patients still have some soft tissue defects after complete healing from surgical interventions. These are excess soft tissue, high attached fraena and firmed tethering scares. These soft tissue defects result... | 10.5978/islsm.17-CR-02 | 28,740,330 | Laser therapy | 2,017 | ||
Small-cell tumors of the liver: a cytological study of 91 cases and a review of the literature. | This study was designed to consider the cytomorphological spectrum, differential diagnosis, and the role of ancillary studies in small-cell tumors of the liver. Three independent pathologists reviewed cytological slides from 91 cases of small-cell tumors of the liver. The results were compared with the findings of thre... | 10.1002/dc.20255 | 15,945,087 | D000230:Adenocarcinoma; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D006528:Carcinoma, Hepatocellular; D018278:Carcinoma, Neuroendocrine; D018288:Carcinoma, Small Cell; D018281:Cholangiocarcinoma; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohis... | Diagnostic cytopathology | 2,005 | D018396:Mucin-1; D009418:S100 Proteins; D014746:Vimentin; D007633:Keratins |
Analysis of microtubule-mediated intracellular viral transport. | Host microtubules and motor proteins are crucial to the intracellular transport of a number of viruses. Disruption of microtubules or suppression of motor functions can remarkably inhibit the movement of viruses in host cells. It is now known that incoming viruses use motor proteins to travel along microtubules from th... | 10.1007/978-1-59745-442-1_12 | 18,085,229 | D000256:Adenoviridae; D001692:Biological Transport; D002460:Cell Line; D002462:Cell Membrane; D002478:Cells, Cultured; D000072159:Dynactin Complex; D006801:Humans; D042541:Intracellular Space; D008856:Microscopy, Fluorescence; D008869:Microtubule-Associated Proteins; D008870:Microtubules; D020409:Molecular Motor Protei... | Methods in molecular medicine | 2,007 | D000072159:Dynactin Complex; D008869:Microtubule-Associated Proteins; D020409:Molecular Motor Proteins; D014966:Xanthenes; C034657:Texas red |
Analysis and discussion on formation and control of dioxins generated from municipal solid waste incineration process. | Dioxins are a kind of persistent organic pollutants (POPs) with extremely toxic. Municipal solid waste incineration (MSWI) process has become one of the most dominant discharge sources of dioxins. A comprehensive discussion about dioxin formation mechanisms was reviewed in this paper, and the mechanisms of high-tempera... | 10.1080/10962247.2022.2100843 | 35,816,420 | D001572:Benzofurans; D002244:Carbon; D002713:Chlorine; D060729:Coal Ash; D000072318:Dibenzofurans; D000072338:Dibenzofurans, Polychlorinated; D004147:Dioxins; D017745:Incineration; D010100:Oxygen; D000083462:Persistent Organic Pollutants; D000072317:Polychlorinated Dibenzodioxins; D062611:Solid Waste | Journal of the Air & Waste Management Association (1995) | 2,022 | D001572:Benzofurans; D060729:Coal Ash; D000072318:Dibenzofurans; D000072338:Dibenzofurans, Polychlorinated; D004147:Dioxins; D000072317:Polychlorinated Dibenzodioxins; D062611:Solid Waste; D002713:Chlorine; D002244:Carbon; D010100:Oxygen |
Cholera toxin, cyclic AMP, and the firefly flash. | Cholera toxin, injected into living fireflies, caused a delayed, non-hormone-dependent activation of adenylate cyclase, an elevation of cyclic AMP levels, and a brilliant persistent glow of the firefly light organ 8-20 hours following injection. During periods of spontaneous flashing, onset of toxin-induced glowing was... | 2,987,320 | D000262:Adenylyl Cyclases; D000818:Animals; D002772:Cholera Toxin; D001517:Coleoptera; D000242:Cyclic AMP; D004789:Enzyme Activation; D008163:Luminescent Measurements; D008297:Male; D009655:Octopamine | Journal of cyclic nucleotide and protein phosphorylation research | 1,985 | D009655:Octopamine; D002772:Cholera Toxin; D000242:Cyclic AMP; D000262:Adenylyl Cyclases | |
The impact of a psychosocial support program on survival with breast cancer: the importance of selection bias in program evaluation. | A retrospective follow-up study was conducted to assess the impact of a psychosocial support program on survival with breast cancer. One-hundred and two nonparticipants were individually matched to 34 participants on several prognostic factors, and both groups were followed from date of cancer diagnosis (1971-1980) unt... | 10.1016/0021-9681(84)90135-8 | 6,715,493 | D000328:Adult; D000368:Aged; D001943:Breast Neoplasms; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D011788:Quality of Life; D012189:Retrospective Studies; D012657:Self-Help Groups; D012931:Social Environment; D012944:Social Support | Journal of chronic diseases | 1,984 | |
Image approximation from gray scale ``medial axes''. | Several types of gray-weighted ``medial axes'' have been defined. This paper shows that one of them, the min-max medial axis, can be used to reconstruct good approximations to the original image based on a relatively small amount of information. | 10.1109/tpami.1981.4767172 | 21,868,991 | IEEE transactions on pattern analysis and machine intelligence | 1,981 | ||
Synergistic enhancement of cancer therapy using a combination of docetaxel and photothermal ablation induced by single-walled carbon nanotubes. | BACKGROUND
Single-walled carbon nanotubes (SWNT) are poorly soluble in water, so their applications are limited. Therefore, aqueous solutions of SWNT, designed by noncovalent functionalization and without toxicity, are required for biomedical applications.
METHODS
In this study, we conjugated docetaxel with SWNT via ... | 10.2147/IJN.S24167 | 22,114,495 | D055011:Ablation Techniques; D000818:Animals; D000970:Antineoplastic Agents; D045744:Cell Line, Tumor; D002470:Cell Survival; D003131:Combined Modality Therapy; D000077143:Docetaxel; D004337:Drug Carriers; D005260:Female; D006801:Humans; D053685:Laser Therapy; D051379:Mice; D008807:Mice, Inbred BALB C; D008856:Microsco... | International journal of nanomedicine | 2,011 | D000970:Antineoplastic Agents; D004337:Drug Carriers; C526428:NGR peptide; D037742:Nanotubes, Carbon; D009842:Oligopeptides; D013501:Surface-Active Agents; D043823:Taxoids; D000077143:Docetaxel |
Low molecular weight self-assembling peptide-based materials for cell culture, antimicrobial, anti-inflammatory, wound healing, anticancer, drug delivery, bioimaging and 3D bioprinting applications. | In this review, we have focused on the design and development of low molecular weight self-assembling peptide-based materials for various applications including cell proliferation, tissue engineering, antibacterial, antifungal, anti-inflammatory, anticancer, wound healing, drug delivery, bioimaging and 3D bioprinting. ... | 10.1039/d0sm01136c | 33,073,836 | D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D062028:Bioprinting; D018929:Cell Culture Techniques; D008970:Molecular Weight; D010455:Peptides; D004364:Pharmaceutical Preparations; D014945:Wound Healing | Soft matter | 2,020 | D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D010455:Peptides; D004364:Pharmaceutical Preparations |
Hemoglobin-binding site on human haptoglobin. Identification of lysyl residues participating in the binding. | The locus of human haptoglobin (Hp) molecules that interacts with human hemoglobin (Hb) was examined by the differential labeling technique. First, amino groups of Hp were extensively labeled with ethyl acetimidate (EAI) either in the free state (experiment A) or in the equimolar complex with Hb (experiment B). Each of... | 1,618,843 | D000595:Amino Acid Sequence; D000596:Amino Acids; D001665:Binding Sites; D002851:Chromatography, High Pressure Liquid; D006242:Haptoglobins; D006454:Hemoglobins; D006801:Humans; D008239:Lysine; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010449:Peptide Mapping | The Journal of biological chemistry | 1,992 | D000596:Amino Acids; D006242:Haptoglobins; D006454:Hemoglobins; D008239:Lysine | |
Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis. | We attempted to elicit active anaphylaxis to ovalbumin, or passive IgE- or IgG1-dependent anaphylaxis, in mice lacking either the Fc epsilonRI alpha chain or the FcR gamma chain common to Fc epsilonRI and Fc gammaRI/III, or in mice lacking mast cells (KitW/ KitW-v mice), and compared the responses to those in the corre... | 10.1172/JCI119255 | 9,062,348 | D000707:Anaphylaxis; D000818:Animals; D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D015550:Cell Degranulation; D005260:Female; D006323:Heart Arrest; D006339:Heart Rate; D007114:Immunization; D007073:Immunoglobulin E; D007074:Immunoglobulin G; D008297:Male; D008407:Mast Cells; D051379:Mice; D00880... | The Journal of clinical investigation | 1,997 | D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G; D017455:Receptors, IgE; D017452:Receptors, IgG; D007073:Immunoglobulin E; D010047:Ovalbumin |
IPG with electrodic plateaus (and other unusual procedures for 2-DE). | We describe some simple changes to the geometry of the IPG strips that make them suitable to the loading of very large sample volumes and of high-salt solutions. Of special relevance is the possibility of using strips with immobilized plateau(s) to either side of the gradient, or to both, also in connection with in-gel... | 10.1002/elps.200600722 | 17,640,092 | D000818:Animals; D001797:Blood Protein Electrophoresis; D004566:Electrodes; D015180:Electrophoresis, Gel, Two-Dimensional; D006863:Hydrogen-Ion Concentration; D051381:Rats; D012709:Serum Albumin | Electrophoresis | 2,007 | D012709:Serum Albumin |
Ammonia inhibits cAMP-regulated intestinal Cl- transport. Asymmetric effects of apical and basolateral exposure and implications for epithelial barrier function. | The colon, unlike most organs, is normally exposed to high concentrations of ammonia, a weak base which exerts profound and diverse biological effects on mammalian cells. The impact of ammonia on intestinal cell function is largely unknown despite its concentration of 4-70 mM in the colonic lumen. The human intestinal ... | 10.1172/JCI118268 | 7,593,599 | D000641:Ammonia; D002460:Cell Line; D016764:Cell Polarity; D002712:Chlorides; D000242:Cyclic AMP; D017097:Electric Impedance; D006801:Humans; D007413:Intestinal Mucosa; D017136:Ion Transport; D007770:L-Lactate Dehydrogenase | The Journal of clinical investigation | 1,995 | D002712:Chlorides; D000641:Ammonia; D000242:Cyclic AMP; D007770:L-Lactate Dehydrogenase |
Femininity Concerns and Feelings About Menstruation Cessation Among Lesbian, Bisexual, and Heterosexual Women: Implications for Menopause. | Women differ in how they psychologically respond to the end of menstruation and onset of menopause; however, little empirical evidence exists for understanding how sexual orientation and gendered dynamics contribute to menstrual experiences in middle-to-late adulthood. We investigated if women's attitudes toward the ce... | 10.1089/jwh.2020.8757 | 33,769,080 | D000328:Adult; D004644:Emotions; D005260:Female; D057227:Femininity; D020010:Heterosexuality; D006801:Humans; D008297:Male; D008593:Menopause; D008598:Menstruation; D012725:Sexual Behavior; D000072339:Sexual and Gender Minorities; D014481:United States | Journal of women's health (2002) | 2,021 | |
Effect of local A-site strain on dipole stability in A6GaNb9O30 (A = Ba, Sr, Ca) tetragonal tungsten bronze relaxor dielectrics. | A series of isovalently A-site substituted relaxor dielectric tetragonal tungsten bronzes of general formula Ba(6-x-y)Sr(x)Ca(y)GaNb(9)O(30) were investigated. The long-range (average) crystal structure as determined by conventional diffraction techniques varies monotonically according to Vegard's law. The dielectric p... | 10.1039/c4dt03936j | 25,687,218 | Dalton transactions (Cambridge, England : 2003) | 2,015 | ||
MELD and other predictors of survival after liver transplantation. | BACKGROUND
This study examined how reliable is the pre-transplant model for end-stage liver disease (MELD) score in predicting post-transplantation survival and analyzed variables associated with patient survival.
METHODS
A cohort study was conducted. Receiver operating characteristic curve c-statistics were used to ... | 10.1111/j.1399-0012.2008.00943.x | 19,210,688 | D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D006528:Carcinoma, Hepatocellular; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D017093:Liver Failure; D008113:Liver Neoplasms; D016031:Liver Transpl... | Clinical transplantation | 2,009 | |
Ray scattering model for spherical transparent particles. | We propose a model for the reflectance of a particle medium made of identical, large, spherical, and absorbing particles in a clear binder. A 3D geometrical description of light scattering is developed by relying on the laws of geometrical optics. The amount of light backscattered by a single particle is determined as ... | 10.1364/josaa.25.001521 | 18,594,607 | Journal of the Optical Society of America. A, Optics, image science, and vision | 2,008 | ||
Characterization of the genes specifying two metacyclic variable antigen types in Trypanosoma brucei rhodesiense. | Bloodstream trypanosomes evade the immune system of their mammalian host by sequentially expressing a large number of different variable surface glycoproteins (VSGs). In contrast, metacyclic trypanosomes, the final developmental stage in the tsetse fly, express a much more restricted set of VSGs. These metacyclic VSGs ... | 10.1073/pnas.81.21.6642 | 6,593,722 | D000818:Animals; D000953:Antigens, Protozoan; D000954:Antigens, Surface; D001483:Base Sequence; D004247:DNA; D004274:DNA, Recombinant; D006023:Glycoproteins; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger; D014345:Trypanosoma | Proceedings of the National Academy of Sciences of the United States of America | 1,984 | D000953:Antigens, Protozoan; D000954:Antigens, Surface; D004274:DNA, Recombinant; D006023:Glycoproteins; D012333:RNA, Messenger; D004247:DNA |
Second impact syndrome. | Diffuse cerebral swelling with delayed catastrophic deterioration, a known complication of brain trauma, has been postulated to occur after repeated concussive brain injury in sports--the "second impact syndrome" (SIS). Certain current concussion management guidelines are contingent upon this assumption. We established... | 10.1212/wnl.50.3.677 | 9,521,255 | D001265:Athletic Injuries; D001930:Brain Injuries; D012090:Cumulative Trauma Disorders; D005538:Football; D006801:Humans | Neurology | 1,998 | |
The effect of an illustrated pamphlet decision-aid on the use of prostate cancer screening tests. | BACKGROUND
Prostate cancer screening with serum prostate-specific antigen (PSA) and digital rectal examination (DRE) continues to increase. Our goal was to test the effect of a prostate cancer screening decision-aid on patients' knowledge, beliefs, and use of prostate cancer screening tests.
METHODS
Our study was a r... | 10,836,772 | D000368:Aged; D000369:Aged, 80 and over; D003657:Decision Making; D006266:Health Education; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D010174:Pamphlets; D010342:Patient Acceptance of Health Care; D011471:Prostatic Neoplasms; D018709:Statist... | The Journal of family practice | 2,000 | ||
Action sequence for layperson cardiopulmonary resuscitation. | Although some minor modifications were forged, the general consensus was to maintain most of the current guidelines for phone first/phone fast, no-assisted-ventilation CPR, the A-B-C (vs C-A-B) sequence of CPR, and the recovery position. The decisions to leave these guidelines as they are were based on a lack of eviden... | 10.1067/mem.2001.114175 | 11,290,966 | D000328:Adult; D000367:Age Factors; D016887:Cardiopulmonary Resuscitation; D002648:Child; D002983:Clinical Competence; D004631:Emergency Medical Service Communication Systems; D004632:Emergency Medical Services; D019317:Evidence-Based Medicine; D006323:Heart Arrest; D006801:Humans; D011187:Posture; D011674:Pulse; D0136... | Annals of emergency medicine | 2,001 | |
Voice feature characteristic in morbid obese population. | BACKGROUND
Morbid obesity is highly prevalent in the Western World, and its consequences present a real public health challenge. Voice alterations can represent one of these consequences and represent an opportunity for interference with therapeutic methods. This particularly features of the individual's voice was the ... | 10.1007/s11695-009-9959-7 | 19,763,710 | D000328:Adult; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid; D011446:Prospective Studies; D014831:Voice; D014832:Voice Disorders; D014833:Voice Quality; D055815:Young Adult | Obesity surgery | 2,011 | |
Association of misexpression with sterility in hybrids of Drosophila simulansand D. mauritiana. | Recent studies have identified genes associated with hybrid sterility and other hybrid dysfunctions, but the consequences of introgressions of these "speciation genes" are often poorly understood. Previously, we identified a panel of genes that are underexpressed in sterile male hybrids of Drosophila simulans and D. ma... | 10.1007/s00239-004-2622-y | 15,486,701 | D000818:Animals; D001483:Base Sequence; D017931:DNA Primers; D004330:Drosophila; D005786:Gene Expression Regulation; D017344:Genes, Insect; D014644:Genetic Variation; D005838:Genotype; D006824:Hybridization, Genetic; D008297:Male; D008969:Molecular Sequence Data; D012098:Reproduction; D020133:Reverse Transcriptase Poly... | Journal of molecular evolution | 2,004 | D017931:DNA Primers |
Clap and fling mechanism with interacting porous wings in tiny insect flight. | The aerodynamics of flapping flight for the smallest insects such as thrips is often characterized by a 'clap and fling' of the wings at the end of the upstroke and the beginning of the downstroke. These insects fly at Reynolds numbers (Re) of the order of 10 or less where viscous effects are significant. Although this... | 10.1242/jeb.084897 | 25,189,374 | D000818:Animals; D001696:Biomechanical Phenomena; D005426:Flight, Animal; D057446:Hydrodynamics; D008954:Models, Biological; D061149:Thysanoptera; D014741:Video Recording; D014921:Wings, Animal | The Journal of experimental biology | 2,014 | |
Impasse or pseudo-impasse in the psychotherapy of an inhibited writer. | This paper describes the interactions of a patient and her therapist in the course of psychoanalytic psychotherapy, during which there occurred two significant impasse enactments. At first sight, each resembled a classical impasse. On further review of the case, the interactions took on a different texture that we have... | 10.1176/appi.psychotherapy.1999.53.1.74 | 10,207,588 | D000184:Acting Out; D000328:Adult; D001008:Anxiety Disorders; D003220:Conflict, Psychological; D003379:Countertransference; D005260:Female; D006801:Humans; D007266:Inhibition, Psychological; D008960:Models, Psychological; D016584:Panic Disorder; D011369:Professional-Patient Relations; D011575:Psychoanalytic Therapy; D0... | American journal of psychotherapy | 1,999 | |
Bruxism physiology and pathology: an overview for clinicians. | Awake bruxism is defined as the awareness of jaw clenching. Its prevalence is reported to be 20% among the adult population. Awake bruxism is mainly associated with nervous tic and reactions to stress. The physiology and pathology of awake bruxism is unknown, although stress and anxiety are considered to be risk factor... | 10.1111/j.1365-2842.2008.01881.x | 18,557,915 | D000328:Adult; D000368:Aged; D001143:Arousal; D002012:Bruxism; D003766:Dental Occlusion; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008410:Masticatory Muscles; D008875:Middle Aged; D017286:Polysomnography; D012890:Sleep; D013315:Stress, Psychological | Journal of oral rehabilitation | 2,008 | |
Bayes' theorem applied to perimetric progression detection in glaucoma: from specificity to positive predictive value. | PURPOSE
To estimate the specificity of a clinical evaluation of a series of visual fields and to calculate the positive predictive value of progression.
METHODS
The specificity of a clinical evaluation of a series of visual fields was estimated using nonparametric ranking and probability calculus. The positive predic... | 10.1007/s00417-004-1065-x | 15,578,199 | D001499:Bayes Theorem; D018450:Disease Progression; D005189:False Positive Reactions; D005901:Glaucoma; D006801:Humans; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D058609:Visual Field Tests; D014794:Visual Fields | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie | 2,005 | |
Formalin-killed versus heat-killed Legionella pneumophila serogroup 1 antigen in the indirect immunofluorescence assay for legionellosis. | Indirect immunofluorescence assay titers of human sera obtained against the Legionella pneumophila serogroup 1 antigen (Philadelphia 1 strain) killed with 10% Formalin showed a tendency to be lower than those obtained against the reference heat-killed antigen (geometric mean titer of 194 and 370, respectively) when all... | 10.1128/jcm.16.5.979-981.1982 | 6,759,533 | D000942:Antigens, Bacterial; D005455:Fluorescent Antibody Technique; D005557:Formaldehyde; D006358:Hot Temperature; D006801:Humans; D007875:Legionella; D007877:Legionnaires' Disease | Journal of clinical microbiology | 1,982 | D000942:Antigens, Bacterial; D005557:Formaldehyde |
Test security in medicolegal cases: proposed guidelines for attorneys utilizing neuropsychology practice. | In the context of forensic neuropsychological assessments, the professional interaction of law and psychology is viewed primarily as one where the retaining attorney or court dictates its needs to psychologists when resolving legal disputes. While this perspective is conceptually accurate, the positive and practical co... | 10.1093/arclin/acp062 | 19,778,915 | D003219:Confidentiality; D004995:Ethics, Professional; D005104:Expert Testimony; D005555:Forensic Psychiatry; D017408:Guidelines as Topic; D006801:Humans; D007603:Jurisprudence; D033241:Lawyers; D009483:Neuropsychological Tests; D009484:Neuropsychology | Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists | 2,009 | |
Somatic embryogenesis, plant regeneration and cyanogenesis in Manihot glaziovii Muell. Arg. (ceara rubber). | The report describes a system for somatic embryogenesis and direct plant regeneration from the embryos of Manihot glaziovii. Somatic embryos were obtained by culturing young leaf lobes (3-6 mm long) adjacent to the apex in Murashige and Skoog medium containing 18 μM 2,4-dichlorophenoxy acetic acid for 20 days and then ... | 10.1007/s002990050769 | 30,754,896 | Plant cell reports | 2,000 | ||
Structure-based protein NMR assignments using native structural ensembles. | An important step in NMR protein structure determination is the assignment of resonances and NOEs to corresponding nuclei. Structure-based assignment (SBA) uses a model structure ("template") for the target protein to expedite this process. Nuclear vector replacement (NVR) is an SBA framework that combines multiple sou... | 10.1007/s10858-008-9230-x | 18,365,752 | D000465:Algorithms; D002352:Carrier Proteins; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D058619:Maltose-Binding Proteins; D011487:Protein Conformation; D011506:Proteins; D015203:Reproducibility of Results; D025801:Ubiquitin | Journal of biomolecular NMR | 2,008 | D002352:Carrier Proteins; D058619:Maltose-Binding Proteins; D011506:Proteins; D025801:Ubiquitin |
[DFT and Raman Scattering Studies of Benzimidazole]. | The Raman spectra of carbendazim, thiabendazole and benomyl were collected by laser Raman spectrometer. The molecules of the three pesticides were optimized and calculated by B3LYP hybrid functional and 6-31G(d, p) basis set. The results showed that the calculated value anastomosed preferably to measure value. Vibratio... | 26,601,367 | D001562:Benzimidazoles; D010573:Pesticide Residues; D013059:Spectrum Analysis, Raman | Guang pu xue yu guang pu fen xi = Guang pu | 2,015 | D001562:Benzimidazoles; D010573:Pesticide Residues | |
The role of induction and adjuvant chemotherapy in combination with concurrent chemoradiotherapy for nasopharyngeal cancer: a Bayesian network meta-analysis of published randomized controlled trials. | Whether the addition of induction chemotherapy (IC) or adjuvant chemotherapy (AC) to concurrent chemoradiotherapy (CCRT) is superior to CCRT alone for locally advanced nasopharyngeal cancer is unknown. A Bayesian network meta-analysis was performed to investigate the efficacy of CCRT, IC + CCRT, and CCRT + AC on locall... | 10.2147/OTT.S96983 | 26,793,000 | OncoTargets and therapy | 2,016 | ||
Effects of age and parental history of alcoholism on EEG findings in mission Indian children and adolescents. | BACKGROUND
Many, but not all, Native American tribes have some of the highest rates of alcohol abuse and dependence. Yet, risk factors for the development of problem drinking in these high risk groups remain largely unknown. In primarily Euroamerican populations, electrophysiological variables have been associated with... | 11,371,716 | D000293:Adolescent; D000367:Age Factors; D000437:Alcoholism; D000513:Alpha Rhythm; D000704:Analysis of Variance; D001611:Beta Rhythm; D002648:Child; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007198:Indians, North American; D008297:Male; D010641:Phenotype; D012737:Sex Factors | Alcoholism, clinical and experimental research | 2,001 |
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