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21367826 | Alignment efficiency and discomfort of three orthodontic archwire sequences: a randomized clinical trial. | AIM: To compare the efficiency of orthodontic archwire sequences produced by three manufacturers.DESIGN: Prospective, randomized clinical trial with three parallel groups.SETTING: Private orthodontic practice in Caloundra, QLD, Australia.SUBJECTS AND METHODS: One hundred and thirty-two consecutive patients were randomi... | [
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17240469 | Characterization of a homologous-region-binding protein from white spot syndrome virus by phage display. | Homologous regions (hrs) of white spot syndrome virus (WSSV) might serve as origins of DNA replication or be involved in transcriptional regulation. To characterize the interaction between hrs of WSSV and the viral proteins, in this investigation, phage display technology was used. WSSV genomic DNA was sheared by sonic... | [
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11780663 | Use of a Shack-Hartmann aberrometer to assess the optical outcome of corneal transplantation in a keratoconic eye. | We report the optical outcome of corneal transplantation treatment on a keratoconic eye as measured with a Shack-Hartmann aberrometer, and we compare the results with the recovery of visual acuity after surgery. Before surgery, the naked keratoconic eye exhibited extremely large aberrations that could not be measured u... | [
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11578051 | Examining location-based and object-based components of inhibition of return in static displays. | Tipper and Colleagues (e.g., Jordan & Tipper, 1998; Tipper, Driver, & Weaver, 1991; Tipper, Weaver, Jerreat, & Burak, 1994) have provided support for inhibition of return (IOR) being composed of a location-based and an object-based component. They were able to separate out the effects of location-based and object-based... | [
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2580732 | Sex differences in long-term gonadectomized rats: monoamine levels and [3H]nitroimipramine binding in brain nuclei. | The levels of norepinephrine, dopamine, serotonin and the serotonin metabolite 5-hydroxyindoleacetic acid were measured in microdissected brain nuclei from long-term gonadectomized male and female rats. Females had 50 and 120% higher levels of serotonin in the anterior hypothalamic nucleus (AH) and arcuate-median emine... | [
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15345750 | Inhibition of KATP channel activity augments baroreflex-mediated vasoconstriction in exercising human skeletal muscle. | In the present investigation we examined the role of ATP-sensitive potassium (K(ATP)) channel activity in modulating carotid baroreflex (CBR)-induced vasoconstriction in the vasculature of the leg. The CBR control of mean arterial pressure (MAP) and leg vascular conductance (LVC) was determined in seven subjects (25 +/... | [
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30231026 | New polybranchiaspiform fishes (Agnatha: Galeaspida) from the Middle Palaeozoic of China and their ecomorphological implications. | The 438-370-million-year-old galeaspids, diversified armoured jawless vertebrates ('ostracoderms') from China and northern Vietnam, were assumed to have a benthic feeding habit in a coastal, marine environment. Here, we describe two new genera of galeaspid fishes, Platylomaspis gen. nov. and Nanningaspis gen. nov. from... | [
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9001988 | Dermatofibroma with granular cells. | A new histologic variant of dermatofibroma, only briefly alluded to in dermatological literature is reported. This tumor was located in the back of a 24-year-old man. It was present for about 2 years and had a history of trauma 2 months before excision. The lesion showed similar characteristics to those of conventional... | [
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21553243 | Impaired early- but not late-phase insulin secretion in subjects with impaired fasting glucose. | Subjects with impaired fasting glucose (IFG) are at increased risk for type 2 diabetes. We recently demonstrated that IFG subjects have increased hepatic insulin resistance with normal insulin sensitivity in skeletal muscle. In this study, we quantitated the insulin secretion rate from deconvolution analysis of the pla... | [
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573210 | Effects of captivity on glucose tolerance in dogs. | Captivity decreased tolerance to glucose and increased blood serotonin levels in 6 normal dogs investigated. Return to freedom brought normalization in the glucose tolerance test and reverted blood serotonin to control levels. | [
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1156309 | Experimental hyperthyroidism III: Contractile responses to propranolol of the intact heart and of the isolated ventricular myocardium. | The effect of propranolol on cardiac mechanics and haemodynamics was examined on isolated papillary muscle as well as in situ in the closed thorax in euthyroid and hyperthyroid cats. Under propranolol there occurred on isolated papillary muscle significant decreases of muscle contraction, contraction velocity, isometri... | [
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3518124 | [Clinical significance of echography in the diagnosis of portal circulatory disorders]. | Forty-one patients with the endoscopically diagnosed varicose veins of the esophagus and stomach were examined. The echograms of 32 patients with liver cirrhosis showed the impoverishment of the vascular pattern of the liver parenchyma, dilatation of the portal, superior mesenterial and splenic veins, enlargement of th... | [
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15620375 | Purification, characterisation and crystallisation of photosystem II from Thermosynechococcus elongatus cultivated in a new type of photobioreactor. | The thermophilic cyanobacterium Thermosynechococcus elongatus was cultivated under controlled growth conditions using a new type of photobioreactor, allowing us to optimise growth conditions and the biomass yield. A fast large-scale purification method for monomeric and dimeric photosystem II (PSII) solubilized from th... | [
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6715835 | Infected mucous cyst of the finger. | The potentially serious complication of septic arthritis of the distal interphalangeal joint of the finger secondary to an infected mucous cyst is documented with a report of four cases seen within the past 6 years. Debridement, open packing, and antibiotic therapy resulted in satisfactory control of the infection in t... | [
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10821972 | Phylogenetic analysis suggests only one serotype of Japanese encephalitis virus. | Phylogenetic analysis was performed for different genome regions of Japanese encephalitis virus (JEV). Similar genetic groupings were identified for all analyzed genome regions including complete genomes. More extensive analysis was performed for 92 isolates (complete envelope sequences) available in the GenBank. Resul... | [
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6976144 | Biphasic pattern of bacterial infection in multiple myeloma. | Since the 1960s, gram-negative bacilli have become commoner pathogens than Streptococcus pneumoniae in multiple myeloma. To investigate this trend, we analyzed 75 bacterial infections in 57 patients with myeloma. Episodes of infection with Streptococcus pneumoniae and Haemophilus influenzae occurred at presentation, ea... | [
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26085532 | Association Between Diabetes, Obesity, and Short-Term Outcomes Among Patients Surgically Treated for Ankle Fracture. | BACKGROUND: Although obesity is widely accepted as a risk factor for surgical complications following orthopaedic surgery, the literature is unclear with regard to the effect of obesity on outcomes of ankle fracture surgery, particularly in the setting of competing risks from diabetes. We hypothesized that obesity woul... | [
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26113109 | Cigarette Smoke and Estrogen Signaling in Human Airway Smooth Muscle. | AIMS: Cigarette smoke (CS) in active smokers and second-hand smoke exposure exacerbate respiratory disorders such as asthma and chronic bronchitis. While women are known to experience a more asthmatic response to CS than emphysema in men, there is limited information on the mechanisms of CS-induced airway dysfunction. ... | [
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31581904 | LGBTQ+ based discrimination is associated with ptsd symptoms, dissociation, emotion dysregulation, and attachment insecurity among LGBTQ+ adults who have experienced Trauma. | Objectives: LGBTQ+ based discrimination is a form of insidious trauma and minority stress, and is associated with poor mental health. However, there is a dearth of research on the impact of discrimination on the psychological functioning of LGBTQ+ individuals who have experienced trauma. The current study seeks to reme... | [
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6838787 | High birthweight in an ethnic group of low socioeconomic status. | Analysis of 14 219 births in West Jerusalem showed that infants of North African origin had a higher birthweight than infants of other ethnic groups. The group of mothers of North African origin included a relatively high proportion from the lowest social classes. The observed excess birthweight was apparent after allo... | [
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11353751 | Metabolism of butadiene monoxide by freshly isolated hepatocytes from mice and rats: different partitioning between oxidative, hydrolytic, and conjugation pathways. | 1,3-Butadiene (BD) is a multisite carcinogen in rodents, with mice being much more susceptible than rats. This species difference in carcinogenicity has been attributed to differences in metabolism. In this study, coordinated metabolism of butadiene monoxide (BMO, 5, 25, and 250 microM), the primary reactive metabolite... | [
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3735409 | The health status of mild to moderate intellectually handicapped adolescents. | To assist in the planning of school health services for the intellectually handicapped, a comprehensive evaluation of physical and emotional health, and social competence was completed on a group of students attending a school for educably retarded adolescents (IQ ranging form 60 to 85). This evaluation included a revi... | [
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17344789 | Oyster mushroom reduced blood glucose and cholesterol in diabetic subjects. | It has been postulated that mushroom has beneficial effect of lowering blood glucose and cholesterol in diabetic subjects. The literature so far searched and found that there was no published data in this regard. This study was undertaken to assess the effect of reducing blood glucose, cholesterol and triglycerides in ... | [
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28161179 | Methane production, ruminal fermentation characteristics, nutrient digestibility, nitrogen excretion, and milk production of dairy cows fed conventional or brown midrib corn silage. | The objective of this study was to examine the effect of replacing conventional corn silage (CCS) with brown midrib corn silage (BMCS) in dairy cow diets on enteric CH4 emission, nutrient intake, digestibility, ruminal fermentation characteristics, milk production, and N excretion. Sixteen rumen-cannulated lactating co... | [
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18329212 | TMJ disorders and pain: assessment by contrast-enhanced MRI. | Though magnetic resonance (MRI) is a widely accepted standard for the assessment of patients with temporomandibular joint (TMJ) disorders, efforts to correlate symptoms to MRI findings have often given controversial results. Aim of this study was to investigate the correlation between TMJ pain and findings of contrast-... | [
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2081675 | The importance of standardised radiographs when assessing hip dysplasia. | The reliability of radiological criteria in the diagnosis of congenital dislocation of the hip is discussed. In a review of 20 normal infant patients the variability of the radiographic relationship between the ossific nucleus of the proximal femoral epiphysis and the acetabulum is identified. Hip arthrography in 10 pa... | [
6546,
4510,
14289,
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14,
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16685567 | [Craniofacial augmentation with porous polyethylene implants (Medpor: first clinical results]. | SUBJECT: Porous polyethylene (Medpor) is an alloplastic material commonly used in craniofacial reconstruction. We report about our first clinical experiences with Medpor for facial augmentation procedures.PATIENTS AND METHODS: We treated 27 patients between 2001 and 2005 (11 female, 16 male) with 48 Medpor-implants. Th... | [
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23749271 | The diagnostic accuracy of transabdominal ultrasonography needs to be considered when managing gallbladder polyps. | BACKGROUND: Transabdominal ultrasonography (TAUS) is the most commonly used modality to diagnose gallbladder (GB) disease. GB polyps are reported in 1-5.6 % of TAUS studies. Histopathologic studies suggest that there is a relationship between GB polyps and GB cancer. Previous literature suggests GB polyps reported on T... | [
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28912301 | Early-onset drug-induced parkinsonism after exposure to offenders implies nigrostriatal dopaminergic dysfunction. | OBJECTIVES: The onset of parkinsonism in patients with drug-induced parkinsonism (DIP) exhibits extensive individual variability following exposure to offending drugs. We investigated whether the individual variations in the onset time of parkinsonism reflected the underlying subtle dopaminergic dysfunction in DIP.METH... | [
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21352253 | Stimulatory lipids accumulate in the mouse liver within 30 min of contact sensitization to facilitate the activation of Na?ve iNKT cells in a CD1d-dependent fashion. | Natural killer T cells with invariant áâ-T cell receptors (TCRs) (iNKT cells) constitute a lipid-responsive arm of the innate immune system that has been implicated in the regulation or promotion of various immune, infectious and neoplastic processes. Contact sensitivity (CS), also known as contact hypersensitivity or ... | [
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16219623 | Phase II study of preoperative oxaliplatin, capecitabine and external beam radiotherapy in patients with rectal cancer: the RadiOxCape study. | BACKGROUND: Preoperative radiotherapy has been shown to decrease the local recurrence rate of patients with locally advanced rectal cancer. Capecitabine and oxaliplatin are both active anticancer agents in the treatment of patients with advanced colorectal cancer and have radiosensitizing properties. Therefore, these d... | [
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1777204 | Neurologic dysfunctions following cardiac surgery. | This article has discussed three major categories of neurologic injury following cardiac surgery. The primary pathophysiologic mechanisms for cerebral injury are thought to be related to reperfusion phenomena and neuronal cellular changes, hypoperfusion, and microemboli while on CPB. The type of symptoms the patient ma... | [
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15690621 | Magnetic resonance imaging and angiography for the prerupture diagnosis of rudimentary uterine horn pregnancy. | Magnetic resonance (MR) imaging and MR angiography were used for the differential diagnosis and preoperative planning of a 17 weeks of age rudimentary horn pregnancy. A 26-year-old primigravida was referred to our hospital with a preliminary diagnosis of abdominal pregnancy. After an inconclusive ultrasound evaluation ... | [
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24077966 | The unfolded protein response has a protective role in yeast models of classic galactosemia. | Classic galactosemia is a human autosomal recessive disorder caused by mutations in the GALT gene (GAL7 in yeast), which encodes the enzyme galactose-1-phosphate uridyltransferase. Here we show that the unfolded protein response pathway is triggered by galactose in two yeast models of galactosemia: lithium-treated cell... | [
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21301926 | Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice. | OBJECTIVE AND DESIGN: Cystic fibrosis transmembrane conductance regulator (CFTR) regulates infection and inflammation. In this study, we investigated whether a lack of functional CFTR in neutrophils would promote lipopolysaccharide (LPS)-induced lung inflammation and injury.MATERIALS AND METHODS: CFTR-inhibited or F508... | [
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2056014 | A University of California State-supported AIDS research award program--a unique state and university partnership in AIDS research. | This article describes the State-supported University of California AIDS research award program and its major accomplishments. It shows how a partnership between a University and a State resulted in the formation of a successful, efficient, and cost-effective AIDS research award program. This program provides funds for... | [
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8736700 | The dual role of S-nitrosoglutathione (GSNO) during thymocyte apoptosis. | Nitric oxide (NO) is known to regulate redox-sensitive signalling pathways in physiology and pathophysiology. Depending on its concentration, the NO-releasing compound S-nitrosoglutathione (GSNO) causes negative and positive regulation of thymocyte apoptosis. At levels below 0.6 mM, GSNO produces deoxyribonucleic acid ... | [
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6470955 | Effect of nonuniform bile flow rate on the rate of biliary excretion of bromophenol blue in the beagle. | Following the intravenous administration of bromophenol blue to beagle dogs, graphs of the biliary excretion rate versus time displayed drastic fluctuations which render them of little value for standard pharmacokinetic modeling purposes. It was shown that these fluctuations in excretion rate are highly correlated with... | [
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169788 | Ibaraki disease and its relationship to bluetongue. | Ibaraki disease, an epizootic disease of cattle in Japan resembling bluetongue, is characterized by fever and lesions affecting the mucous membranes, the skin, the musculature and vascular system. Degeneration of striated muscular tissue is observed in the oesophagus, larynx, pharynx, tongue and the skeletal muscles. O... | [
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21343381 | Overexpression of CXCL1 and its receptor CXCR2 promote tumor invasion in gastric cancer. | BACKGROUND: The chemokine (C-X-C motif) ligand 1 (CXCL1) and its receptor CXCR2 are associated with metastasis potential. Our studies were designed to clarify the CXCL1 and CXCR2 expression patterns and to explore their potential role in gastric cancer.DESIGN: The expression of CXCL1 was determined in primary gastric c... | [
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7909204 | Predominance of beta 3-adrenergic component in catecholamine activation of lipolysis in garden dormouse adipocytes. | The beta 3-adrenoceptor (AR) agonists are potent activators of lipolysis in white adipose tissue. beta-AR agonists were tested here on the lipolytic activity of a hibernator, the garden dormouse (Eliomys quercinus L.). All the agonists exhibited full intrinsic activity; the most potent was the beta 3-AR agonist BRL-373... | [
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28628420 | Value of Multiparametric US in the Assessment of Intratesticular Lesions. | Purpose To evaluate the diagnostic accuracy of multiparametric ultrasonography (US) consisting of gray-scale US, color Doppler US, strain elastography, and contrast agent-enhanced US in the assessment of intratesticular lesions. Materials and Methods Institutional review board approval was obtained for this retrospecti... | [
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25616750 | A satisfaction survey of opioid-dependent patients with methadone maintenance treatment. | The aim of this study was to examine opioid-dependent patients' satisfaction with the methadone maintenance treatment (MMT) program in Malaysia and identify predictors of satisfaction. We used an interviewer-administered questionnaire developed and validated by Rankin Court, New South Wales, Australia. Of 502 patients ... | [
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3986332 | [Early postresuscitation centralization of the blood circulation]. | Experiments on cats were made to study the cardiac output and its main fractions supplying blood to the epi- and subdiaphragmal parts of the body during the postresuscitation period. The phenomenon of early postresuscitation centralization of circulation was established, correlating with the gravity of the sustained te... | [
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8352885 | High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans. | We undertook this study to answer several questions regarding nitrosamine metabolism. Kinetics of nitrosamine metabolism showed the involvement of at least two enzymes in the dealkylation of N-nitrosodiethylamine (NDEA) and N-nitrosodimethylamine (NDMA) in mouse liver microsomes. Coumarin inhibited both reactions compe... | [
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2401652 | Biological efficiency to weaning and to slaughter of crossbred beef cattle with different genetic potential for milk. | Biological efficiency of beef production to weaning and to slaughter was estimated in three groups of cattle reasonably similar in growth and mature size but different in the amount of milk available to the calves (low (L) = Hereford x Angus, medium (M) = Red Poll x Angus and high (H) = Milking Shorthorn x Angus). Effi... | [
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25690141 | [Acceptability of the HPV vaccine among Spanish university students in the pre-vaccine era: a cross-sectional study]. | INTRODUCTION: Cervical cancer (CC), the second most common cause of cancer deaths in women, is associated with the infection of human papillomavirus (HPV) and is more prevalent in women between the ages of 20 and 24. This research is aimed to determine the background about CC, the human papillomavirus infection and its... | [
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7951184 | Risk of complications of first metatarsal head osteotomies with biodegradable pin fixation: Biofix versus Orthosorb. | Bioabsorbable materials for fracture repair have recently become available in the United States. These products have been especially attractive to surgeons that perform elective foot surgeries because an additional surgery is not required to remove internal fixation, and exposed pins and their complications can be avoi... | [
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6148573 | Reduction in prostacyclin platelet receptors in active spontaneous angina. | The number and affinity of binding sites for tritiated prostacyclin (PGI2) in platelets were investigated in twenty-eight patients with spontaneous angina (fourteen in the active and fourteen in the inactive phase) and in nine healthy controls of similar age. Active-phase patients had significantly lower numbers of bot... | [
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16613215 | Effect of probucol on elderly hypercholesterolemic patients in the FAST study. | The present study involved a detailed post hoc comparison of the efficacy and safety of lipid-lowering therapy in elderly hypercholesterolemic patients from the Fukuoka Atherosclerosis Trial (FAST). The FAST cohort of 246 hypercholesterolemic patients included 76 patients who were (75 years old. Patients were randomize... | [
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1402877 | Palladium(II) salt and complexes of spermidine with a six-member chelate ring. Synthesis, characterization, and initial DNA-binding and antitumor studies. | By reaction of spermidine trihydrochloride with K2PdCl4 and PdCl2 at different pH's, we have synthesized the [sperH3]2[PdCl4]3 (I), [PdCl2(sperH)]2[PdCl4] (II), and [(PdCl2)3(sper)2] (III) compounds. The structure of these compounds was studied by IR and 1H NMR; complex II was analyzed by x-ray diffraction. In this com... | [
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"Nucleic Acid Conformation",
"Palladium",
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4524637 | The effect of pressure on the molecular complex of isoalloxazine and adenine. | The effect of pressure to 10 kilobars on the fluorescence characteristics of flavin mononucleotide (FMN), flavin-adenine dinucleotide (FAD), and on complexes of FMN with adenylic acid (AMP), and with I(-) has been studied. The properties measured include peak location, fluorescence yield, and lifetime. From these resul... | [
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"Adenosine Monophosphate",
"Flavin Mononucleotide",
"Flavin-Adenine Dinucleotide",
"Flavins",
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"Pressure",
"Spectrometry, Fluorescence",
"Thermodynamics"
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7158230 | Improved radioassay for human antithyroglobulin. | Human antithyroglobulin (anti-HTg) in serum and tissue cultures can be assayed by coprecipitation with 125I-labelled human thyroglobulin (HTg). Co-precipitation of the antibody from different sera gives roughly parallel curves, so that a standard serum can be used for quantitiation of other sera. By assessing the bindi... | [
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1066,
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"Binding, Competitive",
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26415183 | Prediction of Protein Coding Regions Using a Wide-Range Wavelet Window Method. | Prediction of protein coding regions is an important topic in the field of genomic sequence analysis. Several spectrum-based techniques for the prediction of protein coding regions have been proposed. However, the outstanding issue in most of the proposed techniques is that these techniques depend on an experimentally-... | [
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23562832 | Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. | Cell replacement is an emerging therapy for type 1 diabetes. Pluripotent stem cells have received a lot of attention as a potential source of transplantable â-cells, but their ability to form teratomas poses significant risks. Here, we evaluated the potential of primary mouse gall bladder epithelial cells (GBCs) as tar... | [
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23769388 | Prolonged emergency department length of stay is not associated with worse outcomes in traumatic brain injury. | BACKGROUND: Data suggest that prolonged Emergency Department length of stay (EDLOS) has a detrimental effect on outcomes in some critically ill patients. However, the relationship between EDLOS and outcomes in traumatic brain injury (TBI) has not been examined.OBJECTIVE: Our objective was to determine the effect of EDL... | [
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10212118 | Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-I. | The design, synthesis, and biological evaluation of a family of peptidomimetic inhibitors of protein geranylgeranyltransferase-I (PGGTase-I) are reported. The inhibitors are based on the C-terminal CAAL sequence of many geranylgeranylated proteins. Using 2-aryl-4-aminobenzoic acid derivatives as mimetics for the centra... | [
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18426164 | Protaper--hybrid technique. | UNLABELLED: Crown down preparation is the most known and described technique since the introduction of Nickel Titanium (NiTi) rotary instruments in endodontics. This technique gives good results but has limitations, such as not addressing the initial anatomy of oval or dumb-bell shaped canals. The specific design of th... | [
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6270,
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7165,
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25109664 | Neuropeptide Y activity in the nucleus accumbens modulates feeding behavior and neuronal activity. | BACKGROUND: Neuropeptide Y (NPY) is a hypothalamic neuropeptide that plays a prominent role in feeding and energy homeostasis. Expression of the NPY Y1 receptor (Y1R) is highly concentrated in the nucleus accumbens (Acb), a region important in the regulation of palatable feeding. In this study, we performed a number of... | [
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12423760 | Genetic evidence for a novel thymidylate synthase in the halophilic archaeon Halobacterium salinarum and in Campylobacter jejuni. | A search of the complete genome sequence of the halophilic archaeon Halobacterium salinarum failed to identify a gene homologous to the thymidylate synthase (thyA) gene present in the closely related Haloferax volcanii. To understand the source of thymidine synthesis in Hbt. salinarum, a genomic library of Hbt. salinar... | [
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"Genomic Library",
"Halobacterium salinarum",
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15895123 | [Pulmonary carcinoid tumors--ten years experience]. | Pulmonary carcinoid tumors are rare, accounting for as many as 2% of all pulmonary neoplasms and for 10% of carcinoid tumors overall. Previously classified as bronchial adenomas, actually are classified as neuroendocrine tumors. They have a subclassification into typical classed as low-grade malignant neoplasm and atyp... | [
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8548819 | E. coli SSB activates N4 virion RNA polymerase promoters by stabilizing a DNA hairpin required for promoter recognition. | Bacteriophage N4 virion RNA polymerase transcription of double-stranded promoter-containing DNAs requires supercoiled template and E. coli single-stranded DNA-binding protein (EcoSSB); other single-stranded DNA-binding proteins cannot substitute. The DNA determinants of virion RNA polymerase binding at the promoter com... | [
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3165508 | Radiobiologic risk estimation from dental radiology. Part I. Absorbed doses to critical organs. | The aim of the present study was to generate one consistent set of data for evaluating and comparing radiobiologic risks from different dental radiographic techniques. To accomplish this goal, absorbed doses were measured in fourteen anatomic sites from (1) five different panoramic machines with the use of rare-earth s... | [
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16362316 | An objective technique to measure the depth-of-focus in free space. | BACKGROUND: Determining the depth-of-focus (DOF) objectively in free space is important, as this provides information regarding the range of clear vision under more natural viewing conditions in which target blur, size, and proximal information, as well as other monocular depth cues, are present.METHODS: The DOF was as... | [
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25726113 | The function of the milk-clotting enzymes bovine and camel chymosin studied by a fluorescence resonance energy transfer assay. | Enzymatic coagulation of bovine milk can be divided in 2 steps: an enzymatic step, in which the Phe105-Met106 bond of the milk protein bovine ê-casein is cleaved, and an aggregation step. The aspartic peptidases bovine and camel chymosin (EC 3.4.23.4) are typically used to catalyze the enzymatic step. The most commonly... | [
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305,
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"Caseins",
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] | {
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32138943 | Irritability as a Transdiagnostic Vulnerability Trait:Current Issues and Future Directions. | In recent years, irritability has received increasing attention among mental health professionals given its transdiagnostic associations with diverse forms of psychopathology. In contrast to other emotional states and traits, however, literature addressing associations between irritability and related temperament and p... | [
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] | {
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2148502 | [Increase by ANP and ADH of the duration of activation and deactivation of the cardiopulmonary baroreceptor reflex: modification in the presence of left ventricular hypertrophy]. | The involvement of cardiopulmonary and arterial sinoaortic receptors in the control of antidiuretic hormone (ADH) and atrial natriuretic peptide (ANP) release is still controversial in humans. Moreover, it is not clear if this control may be impaired in hypertensive patients with left ventricular hypertrophy (LVH). We ... | [
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23798628 | Disease patterns of juvenile dermatomyositis from Western India. | A retrospective assessment of clinical characteristics, complications/ associations, laboratory investigations, treatment modalities and outcome in an inceptional cohort of 22 (male-13) children with juvenile dermatomyositis (JDM) receiving treatment at Jaslok Hospital, Mumbai during 1997- 2012 was performed . Mean age... | [
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} |
22729110 | Antinociceptive effects of intrathecal landiolol injection in a rat formalin pain model. | Perioperative beta-blocker administration has recently been recommended for patients undergoing cardiac or other surgery due to the beneficial cardiovascular effects of these agents. In addition, some studies have reported that perioperatively administered beta-blockers also have analgesic effects. In this study, to in... | [
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69,
2968
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"Formaldehyde",
"Injections, Spinal",
"Male",
"Morpholines",
"Pain",
"Proto-Oncogene Proteins c-fos",
"RNA, Messenger",
"Rats",
"Rats, Sprague-Dawley",
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] | {
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16713677 | Bone marrow stromal cells can achieve cure of chronic paraplegic rats: functional and morphological outcome one year after transplantation. | Chronic paraplegia resulting from severe spinal cord injury (SCI) is considered to be an irreversible condition. Nevertheless, recent studies utilizing adult stem cells appear to offer promise in the treatment of this and other neurological diseases. Here, we show that progressive functional motor recovery is achieved ... | [
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18241567 | [Diagnosis and treatment for solitary necrotic nodule of the liver: report of 15 patients]. | OBJECTIVE: To investigate the diagnostic and therapeutic approach of solitary necrotic nodule of the liver (SNNL).METHODS: Fifteen cases were diagnosed as SNNL from June 1999 to December 2005. The clinical characteristics, imaging findings, diagnosis and treatment were analyzed with related literature retrospectively.R... | [
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10780901 | 3-Alkylamino-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1,1-dioxides structurally related to diazoxide and pinacidil as potassium channel openers acting on vascular smooth muscle cells: design, synthesis, and pharmacological evaluation. | A series of 3-alkylamino-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1, 1-dioxides structurally related to diazoxide and pinacidil were synthesized and tested as possible K(ATP) channel openers on isolated pancreatic endocrine tissue as well as on isolated vascular, intestinal, and uterine smooth muscle. In contrast to previous... | [
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2611471 | Ovum donation. | Recent advances in assisted conception and reproductive endocrinology have provided novel avenues for the treatment of couples previously thought to be irreversibly sterile. | [
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29970149 | Assessment of vector competence of UK mosquitoes for Usutu virus of African origin. | BACKGROUND: Usutu virus (USUV) is an emerging zoonotic virus originally from sub-Saharan Africa. It has been introduced into Europe on multiple occasions, causing substantial mortality within the Eurasian blackbird (Turdus merula) population. It is transmitted by the mosquito species Culex pipiens in Europe and Africa.... | [
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15161351 | UV-radiation-induced internalization of the epidermal growth factor receptor requires distinct serine and tyrosine residues in the cytoplasmic carboxy-terminal domain. | The mechanism of UV-radiation-induced EGF receptor (EGFR) internalization remains to be established. In the present study, we found UV-radiation-mediated internalization of the EGFR to be dependent on the cytoplasmic carboxy-terminal region. UV radiation was unable to induce internalization of EGFR carboxy-terminal tru... | [
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15666118 | Clinical results in severe carpal tunnel syndrome and motor nerve conduction studies. | The purposes of this study were to assess the value of motor nerve conduction studies as a prognostic indicator for severe carpal tunnel syndrome (CTS) and to investigate residual nerve disorder after surgery. Fifty hands in 46 patients with severe CTS were followed for at least 6 months after surgery for open carpal t... | [
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22839776 | Cationic polythiophene-surfactant self-assembly complexes: phase transitions, optical response, and sensing. | The absorption and photoluminescence spectra of the cationic conjugated polyelectrolyte poly[3-(6-trimethylammoniumhexyl)thiophene] (P3TMAHT) were observed to be dramatically altered in the presence of anionic surfactants due to self-assembly through ionic complex formation. Small-angle neutron scattering (SANS), UV/vi... | [
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11148043 | Salt dependence of the formation and stability of the signaling state in G protein-coupled receptors: evidence for the involvement of the Hofmeister effect. | We studied the salt dependence of both the stability and the equilibrium of the late photoproducts metarhodopsin I (MI) and II (MII) of the artificial visual pigment 9-demethyl rhodopsin (9dm-Rho). In the photoproducts of 9dm-Rho, all-trans-9-demethyl retinal acts only as a partial agonist, enabling us to study the pho... | [
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29028839 | Interaction of the Human Respiratory Syncytial Virus matrix protein with cellular adaptor protein complex 3 plays a critical role in trafficking. | Human Respiratory Syncytial Virus (HRSV) is a leading cause of bronchopneumonia in infants and the elderly. To date, knowledge of viral and host protein interactions within HRSV is limited and are critical areas of research. Here, we show that HRSV Matrix (M) protein interacts with the cellular adaptor protein complex ... | [
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15332506 | Chemopreventive action of Phyllanthus urinaria Linn on DMBA-induced skin carcinogenesis in mice. | The inhibition of tumor incidence by hydro-alcoholic extract of the whole plant of P. urinaria was evaluated in 6-7 weeks old female albino mice on two-stage process of skin carcinogenesis induced by a single application of 7,12-dimethylbenz(a)anthracene (50 microg/50 microl of acetone), and 2 weeks later, promoted by ... | [
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23132053 | Practical aspects in expression and purification of membrane proteins for structural analysis. | A surge of membrane protein structures in the last few years can be attributed to advances in technologies starting at the level of genomes, to highly efficient expression systems, stabilizing conformational flexibility, automation of crystallization and data collection for screening large numbers of crystals and the m... | [
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26482479 | Arabidopsis KLU homologue GmCYP78A72 regulates seed size in soybean. | Soybean (Glycine max) is one of the most important crops in the world, and its yield is largely determined by grain weight and grain size. However, the genes that regulate soybean seed size have not been identified. CYP78A, which is highly conserved within terrestrial plants, regulates organ development. In Arabidopsis... | [
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20579737 | Monitoring of firefighters exposure to smoke during fire experiments in Portugal. | Forest fires represent a serious threat to public security in Europe due to the large burned area. Moreover, smoke pollution due to forest fire events is an important public health issue for the communities directly affected, and particularly for the personnel involved in firefighting operations. Aiming to contribute t... | [
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19796817 | Estimation of the full marginal costs of port related truck traffic. | NY region is expected to grow by additional 1 million people by 2020, which translates into roughly 70 million more tons of goods to be delivered annually. Due to lack of rail capacity, mainly trucks will haul this volume of freight, challenging an already much constrained highway network. What are the total costs asso... | [
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26478185 | In vitro release studies of insulin from lipid implants in solution and in a hydrogel matrix mimicking the subcutis. | Widely accepted in vitro methodologies for sustained release parenteral drug formulations remain to be established. Hydrogels have been proposed as a release matrix more closely resembling the in vivo conditions for formulations intended for subcutaneous administration. The perspective of the current work was to invest... | [
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27920119 | Randomized trial to reduce emergency visits or hospital admissions using telephone coaching to complex patients. | Background: Comorbidity remains a matter of international interest, given growing prevalence of chronic conditions.Objective: To evaluate the impact that adding a telephone coaching intervention by a family physician to usual care has on reducing resource consumption and improving health status, caregiver burden and qu... | [
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26332741 | Changing a conserved amino acid in R2R3-MYB transcription repressors results in cytoplasmic accumulation and abolishes their repressive activity in Arabidopsis. | Sub-group 4 R2R3-type MYB transcription factors, including MYB3, MYB4, MYB7 and MYB32, act as repressors in phenylpropanoid metabolism. These proteins contain the conserved MYB domain and the ethylene-responsive element binding factor-associated amphiphilic repression (EAR) repression domain. Additionally, MYB4, MYB7 a... | [
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32691556 | [Monoclonal Antibody Against N Terminal 439-451 Epitopes of Anti-Mullerian Hormone and Its Properties]. | Objective: To prepare the specific monoclonal antibody against the N-terminal specific epitope peptide of anti-mullerian hormone (AMH) and to identify its specificity.Methods: Using bioinformatics analysis software to predict the specific peptide fragment of AMH. Then synthesized four antigenic epitope peptide segments... | [
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3745211 | Elongation of actin filaments is a diffusion-limited reaction at the barbed end and is accelerated by inert macromolecules. | We used a fluorescence method to measure the rate constants for the elongation of pyrene-labeled actin filaments in a number of different solvents. The absolute values of the rate constants were established by electron microscopy. Using glycerol, sucrose, or ethylene glycol to vary the solution viscosity, the associati... | [
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21972152 | Mutation of alpha-tubulin genes in trifluralin-resistant water foxtail (Alopecurus aequalis). | BACKGROUND: Trifluralin-resistant biotypes of water foxtail (Alopecurus aequalis) have been identified in wheat fields from northern Kyushu, Japan. Water foxtail is a winter-annual grassy weed, causing substantial crop losses. This study reports on mutation in á-tubulin (TUA) genes from water foxtail, the site of actio... | [
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24198878 | Cost of hospital care for HIV/AIDS infected patients in three general reference hospitals in Lubumbashi, DR Congo: prospective cohort study. | INTRODUCTION: This article analyses the composition of healthcare costs for HIV/AIDS infected patients in a country with limited resources and attempts to identify the factors that influence these costs. The aims are to calculate medical care costs, analysing how they vary depending on patients' income, and to evaluate... | [
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8923749 | The development of spelling procedures in French-speaking, normal and reading-disabled children: effects of frequency and lexicality. | The spelling procedures of normal and reading-disabled French-speaking children matched for reading level were examined. Subjects had to spell frequent and infrequent words containing either inconsistent nondominant graphonemes (e.g., /s/ spelled "c" as in "cigarette," the dominant spelling for /s/ being "s") or consis... | [
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"Achievement",
"Child",
"Dyslexia",
"Female",
"Humans",
"Language",
"Male",
"Phonetics",
"Verbal Learning",
"Vocabulary"
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} |
3125946 | Depletion of central catecholamines reduces pressor responses to arginine vasopressin. | Previous reports that central administration of arginine vasopressin (AVP) increases turnover of brain catecholamines raise the possibility that the pressor responses which follow central administration of AVP may be mediated, in part, by central catecholamines. To test this hypothesis, rats were given intraventricular... | [
30,
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522,
206,
5663,
732,
18404,
3475,
35,
3543,
43,
700
] | [
"Animals",
"Arginine Vasopressin",
"Blood Pressure",
"Brain",
"Catecholamines",
"Heart Rate",
"Hydroxydopamines",
"Injections, Intraventricular",
"Male",
"Oxidopamine",
"Rats",
"Rats, Inbred Strains"
] | {
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"Z": 0
} |
1514690 | Allele-specific and asymmetric polymerase chain reaction amplification in combination: a one step polymerase chain reaction protocol for rapid diagnosis of familial defective apolipoprotein B-100. | We have combined the asymmetric polymerase chain reaction (PCR) with allele-specific PCR to detect a single point mutation. A set of two priming oligonucleotides and a third allele-specific primer were used to identify heterozygotes for a G to A mutation at nucleotide 10,708 in the apolipoprotein B (apo B) gene. The sy... | [
631,
14367,
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1342,
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] | [
"Alleles",
"Apolipoprotein B-100",
"Apolipoproteins B",
"Base Sequence",
"DNA",
"DNA Mutational Analysis",
"Female",
"Humans",
"Hyperlipoproteinemias",
"Male",
"Molecular Sequence Data",
"Nucleic Acid Amplification Techniques",
"Pedigree",
"Polymerase Chain Reaction"
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9851736 | Focused antithrombotic therapy: novel anti-platelet salicylates with reduced ulcerogenic potential and higher first-pass detoxification than aspirin in rats. | The use of aspirin as an anti-platelet drug is limited by its propensity to induce gastric injury and by its adverse effect on vascular prostacyclin formation. Two phenolic non-steroidal anti-inflammatory drugs (salicylic acid and diflunisal) were modified by esterification with a series of O-acyl moieties. The short-t... | [
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830,
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245,
2684,
1394,
2315
] | [
"Animals",
"Anti-Inflammatory Agents",
"Arthritis, Experimental",
"Aspirin",
"Blood Platelets",
"Diflunisal",
"Dose-Response Relationship, Drug",
"Female",
"Fibrinolytic Agents",
"Gastric Mucosa",
"In Vitro Techniques",
"Inactivation, Metabolic",
"Liver",
"Platelet Aggregation",
"Platele... | {
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} |
1987926 | The incidence of ulcerative keratitis among aphakic contact lens wearers in New England. | We conducted a population-based incidence study in five New England states to quantify the risk of ulcerative keratitis associated with contact lens use among aphakic persons. All practicing ophthalmologists in the five-state area were surveyed to identify prospectively all new cases of ulcerative keratitis during a 4-... | [
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] | [
"Adolescent",
"Adult",
"Aphakia, Postcataract",
"Child",
"Contact Lenses",
"Contact Lenses, Extended-Wear",
"Contact Lenses, Hydrophilic",
"Corneal Ulcer",
"Female",
"Humans",
"Incidence",
"Male",
"Middle Aged",
"New England",
"Prospective Studies",
"Random Allocation",
"Risk Factors... | {
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} |
8519594 | Do pancreatic islet cells from neonatal rats have surface receptors or sensors for divalent cations? | The effects of extracellular divalent cations on the intracellular Ca2+ concentration ([Ca2+]i) in neonatal rat islet cells were investigated to determine whether these cells, like several others, have signal-generating surface cation sensors. Raising the external Ca2+ concentration by 1 mM increments triggered either ... | [
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7514,
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35,
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5276,
588
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"Animals",
"Animals, Newborn",
"Calcium",
"Calcium Channel Blockers",
"Calcium Channels",
"Cations, Divalent",
"Cells, Cultured",
"Female",
"Fluorescent Dyes",
"Fura-2",
"Ion Transport",
"Islets of Langerhans",
"Male",
"Rats",
"Rats, Sprague-Dawley",
"Receptors, Cell Surface",
"Signa... | {
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} |
22256585 | [Acute subdural hematoma secondary to cerebrospinal fluid drainage during thoracic endovascular aortic repair (TEVAR): A case report]. | We report a case of acute subdural hematoma which occurred following cerebrospinal fluid (CSF) drainage during thoracic endovascular aortic repair (TEVAR) surgery. A 63-year-old woman was scheduled to receive TEVAR for thoracic-abdominal aneurysm extending from the descending aorta (T10) to 15 mm above the celiac trunk... | [
3439,
1570,
7421,
1050,
6715,
1598,
3334,
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18060,
3,
979,
160,
233
] | [
"Aorta, Thoracic",
"Aortic Aneurysm, Thoracic",
"Celiac Artery",
"Cerebrospinal Fluid",
"Decompression, Surgical",
"Drainage",
"Endovascular Procedures",
"Female",
"Hematoma, Subdural, Acute",
"Humans",
"Intraoperative Complications",
"Middle Aged",
"Stents"
] | {
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"E": 1,
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} |
3117903 | Interleukin-2 stimulates resting human T lymphocytes' response to allogeneic, gamma interferon-treated keratinocytes. | In order to investigate the biologic significance of HLA-DR expression by human keratinocytes, we have examined the possibility that DR-positive keratinocytes become alloantigen presenting cells for resting T cells in the presence of interleukin-2. Using this system, gamma interferon-treated, DR-positive keratinocytes ... | [
622,
51,
4558,
1060,
4354,
6189,
3,
1045,
2384,
5312,
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506,
3450,
1047
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"Antibodies, Monoclonal",
"Cells, Cultured",
"Epidermal Cells",
"Epidermis",
"HLA-D Antigens",
"HLA-DR Antigens",
"Humans",
"Interferon-gamma",
"Interleukin-2",
"Isoantibodies",
"Lymphocyte Activation",
"Recombinant Proteins",
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} |
30976803 | Predictive models of eukaryotic transcriptional regulation reveals changes in transcription factor roles and promoter usage between metabolic conditions. | Transcription factors (TF) are central to transcriptional regulation, but they are often studied in relative isolation and without close control of the metabolic state of the cell. Here, we describe genome-wide binding (by ChIP-exo) of 15 yeast TFs in four chemostat conditions that cover a range of metabolic states. We... | [
6838,
2133,
12746,
1131,
8787,
1624,
5685,
1428,
372,
3371,
4537,
2677
] | [
"Basic-Leucine Zipper Transcription Factors",
"Cluster Analysis",
"Eukaryotic Cells",
"Gene Expression Profiling",
"Gene Ontology",
"Models, Genetic",
"Nitrogen",
"Promoter Regions, Genetic",
"Protein Binding",
"Saccharomyces cerevisiae",
"Saccharomyces cerevisiae Proteins",
"Transcription Fac... | {
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"L": 1,
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"Z": 0
} |
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