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199 | Case 18 | Courses of Treatment | Carcinoma In Situ | 18.1. . Courses of Treatment. Operation + Postoperative radiation therapy.. Operation. 83. 84. Pathology Report. Ductal carcinoma in situ, pathological TN cat. egory (AJCC 2017): pTis. . 1. Size of tumor: 1.1 cm (pTis).. . 2. Nuclear grade: low.. . 3. Necrosis: present.. . 4. Architectural pattern: micropapillary... |
207 | Case 18 | Important Radiologic | Carcinoma In Situ | Important Radiologic. Findings. 81. 82. 18.3. |
213 | Case 18 | Patient History | Carcinoma In Situ | Patient History and Progress. Female/64 years old, post-menopause.. Screen detected mass lesion on right breast. 8 o’clock direction.. Outside result of biopsy:. Right breast 8 o’clock, atypical intraductal. papillary neoplasm, favor ductal carcinoma in. situ.. No family history.. Hypertension, diabetes mellitus.. 18.... |
200 | Case 18 | Courses of Treatment | HR(+) HER2(+) Breast Cancer | 18.1. . Courses of Treatment. Operation + Adjuvant chemotherapy (#4. cycles of doxorubicin and cyclophosphamide. followed by #4 cycles of docetaxel and trastu. zumab) + Post-operative radiation ther. apy + Trastuzumab + Letrozole 2.5 mg/day. with goserelin.. 99. Pathology Report. Invasive Ductal Carcinoma. ... |
208 | Case 18 | Important Radiologic | HR(+) HER2(+) Breast Cancer | Important Radiologic. Findings. 95 96 97. 98. 18.3. |
214 | Case 18 | Patient History | HR(+) HER2(+) Breast Cancer | Patient History and Progress. Female/38 years old, pre-menopause.. Self-detected palpable mass lesion on portion. of outer half of left breast.. No family history.. Lumbar spine disc.. BRCA 1 and 2 mutation: Not examination.. 18.2. |
201 | Case 18 | Courses of Treatment | HR(+) HER2(-) Breast Cancer | Courses of Treatment. Operation (1st & 2nd, Aug. 2010) + Post-. operative radiation therapy + Tamoxifen. 20 mg/day.. Operation (3rd, Jan. 2021) + Adjuvant che. motherapy (docetaxel & cyclophosphamide) +. Letrozole 2.5 mg/day.. Operation (1st, Aug. 2010). comedo.. . 5. Surgical margins:. . (a) superior margin: 3... |
209 | Case 18 | Important Radiologic | HR(+) HER2(-) Breast Cancer | Important Radiologic. Findings. See Figs. 89, 90, 91, 92, 93, 94, 95 and 96.. 18.3. |
215 | Case 18 | Patient History | HR(+) HER2(-) Breast Cancer | S/P unilateral salpingo-oophorectomy, s/p. hysterectomy, Hypertension.. 18.2. |
202 | Case 18 | Courses of Treatment | HR(−) HER2(+) Breast Cancer | 18.1. . Courses of Treatment. Neoadjuvant chemotherapy (#6 cycles of. docetaxel and carboplatin and trastuzumab and. pertuzumab) + Operation + Post-operative radia. tion therapy + Trastuzumab.. . Y. Kwon et al.. 503. 3/3, 3/1HPF).. 4. Intraductal component: absent.. 5. Surgical margins:. . (a) superior margin: 40 ... |
210 | Case 18 | Important Radiologic | HR(−) HER2(+) Breast Cancer | Important Radiologic. Findings. 127 128 129. 130. . Y. Kwon et al.. 501. . . . HR(−) HER2(+) Breast Cancer. 502. 18.3. . After Neoadjuvant. Chemotherapy. 131 132 133. 134. 18.4. |
216 | Case 18 | Patient History | HR(−) HER2(+) Breast Cancer | Patient History and Progress. Female/61 years old, post-menopause.. Self-detected bloody discharge on nipple of. left breast.. No family history.. S/p hysterectomy.. 18.2. |
203 | Case 18 | Courses of Treatment | HR(−) HER2(−) Breast Cancer | 18.1. . Courses of Treatment. Neoadjuvant chemotherapy (#4 cycles of. doxorubicin and cyclophosphamide + #4. cycles of paclitaxel) + Operation + Post-. operative radiation therapy + Adjuvant. capecitabine.. Operation. 130. Pathology Report. . 1. Invasive Ductal Carcinoma.. . (a) Post-chemotherapy status.. .... |
211 | Case 18 | Important Radiologic | HR(−) HER2(−) Breast Cancer | Important Radiologic Findings. 123 124. 125. After Neoadjuvant. Chemotherapy. 126 127 128. 129. 18.3. |
217 | Case 18 | Patient History | HR(−) HER2(−) Breast Cancer | Patient History and Progress. Female/57 years old, post-menopause.. Self-detected palpable mass lesion and skin. change on left breast.. Family history of breast cancer, aunt. (paternal).. No comorbidities.. BRCA 1 and 2 mutation: Not detected.. 18.2. |
204 | Case 18 | Courses of Treatment | Local Recurrence | 18.1. . Courses of Treatment. Left breast IDC→ Operation → Adjuvant. . therapy → Right breast recurrence (IDC).. Primary Treatment. Operation. May 2001 Left modified radical mastectomy. (outside).. Pathology Report. Invasive Ductal Carcinoma. . 1. Size of tumor: 3.0 cm (pT2).. . 2. Lymph nodes: two metastases in 24 ... |
218 | Case 18 | Patient History | Local Recurrence | Patient History and Progress. Female/71 years old, post-menopause.. Screen detected mass lesion on right breast.. No family history.. Diabetes mellitus, Grave’s disease.. BRCA 2 mutation carrier.. 18.2. |
205 | Case 18 | Courses of Treatment | Metastatic Breast Cancer | 18.1. . Courses of Treatment. Left breast cancer → Operation → Ipsilateral. chest wall recurrence → Neoadjuvant chemo. therapy → operation → targeted therapy →. Ipsilateral lymph node recurrence.. Primary Treatment. Negative (0/8). 0. 0. Progesterone. receptor. Negative (0/8). 0. 0. C-erbB2. Positive (3+). Ki-67. Pos... |
219 | Case 18 | Patient History | Metastatic Breast Cancer | Patient History and Progress. Female/64 years old, post-menopause.. No family history.. Hypertension, diabetes mellitus.. 18.2. |
220 | Case 19 | Courses of Treatment | Benign and Proliferative | 19.1. . Courses of Treatment. →2021-08-03 excision, Lt.. Pathology Report. Diagnosis. • Breast, left 1 o’clock, excision:. –. – Fibroadenoma.. –. – Intraductal papilloma with usual ductal. hyperplasia.. • Breast, left 8 o’clock, excision:. –. – Intraductal papilloma with (1) usual ductal. hyperplasia, (2) microcalci... |
228 | Case 19 | Important Radiologic | Benign and Proliferative | Important Radiologic. Findings. 34 35. 36. Benign and Proliferative Case Series. 40. . . . C. W. Lee et al.. 41. 19.3. |
234 | Case 19 | Patient History | Benign and Proliferative | Patient History and Progress. Female/42 years old, pre-menopause.. Screen detected mass lesion on left breast. 8 o’clock direction.. Outside result of biopsy: papillary neoplasm.. No family history.. No comorbidities.. 19.2. |
221 | Case 19 | Courses of Treatment | Carcinoma In Situ | 19.1. . Courses of Treatment:. Operation. Operation. . 89. 90. Carcinoma In Situ. 92. Pathology Report. Right.. Ductal carcinoma in situ. . 1. Post-mammotome status.. . 2. Size of tumor: 0.3 cm, residual.. . 3. Nuclear grade: high.. . 4. Necrosis: absent.. . 5. Architectural pattern: cribriform/solid.. . 6. Ski... |
229 | Case 19 | Important Radiologic | Carcinoma In Situ | Important Radiologic. Findings. 85 86 87. 88. 19.3. |
235 | Case 19 | Patient History | Carcinoma In Situ | Patient History and Progress. Female/48 years old, pre-menopause.. Screen detected diffuse non-mass lesions on. upper, central, and lower portion of left breast.. Screen detected microcalcification on inner. subareolar of right breast.. Outside result of excisional biopsy: bilateral. ductal carcinoma in situ.. No famil... |
222 | Case 19 | Courses of Treatment | HR(+) HER2(+) Breast Cancer | 19.1. . Courses of Treatment. Neoadjuvant chemotherapy (#6 cycles of. docetaxel and carboplatin and trastuzumab. and pertuzumab) + Operation + Post-. operative radiation therapy + Trastuzumab +. Letrozole 2.5 mg/day.. 105. Pathology Report. Invasive Ductal Carcinoma. 1. Post-chemotherapy status.. 2. Size of tum... |
230 | Case 19 | Important Radiologic | HR(+) HER2(+) Breast Cancer | Important Radiologic. Findings. 100 101 102 103. 104. 19.3. |
236 | Case 19 | Patient History | HR(+) HER2(+) Breast Cancer | Patient History and Progress. Female/71 years old, post-menopause.. Self-detected palpable mass lesion on left. breast 11 o’clock direction.. No family history.. Hypertension,. dyslipidemia,. s/p. appendectomy.. 19.2. |
223 | Case 19 | Courses of Treatment | HR(+) HER2(-) Breast Cancer | Courses of Treatment. Operation + Tamoxifen 20 mg/day with leup. rolide acetate.. Operation. Left nipple–areolar complex sparing mastectomy. with immediate implant reconstruction, sentinel. lymph node biopsy (Figs. 106 and 107).. Pathology Report. Invasive Ductal Carcinoma. 1. Size of tumor: 1.7 cm and 0.5 cm (pT1c(2... |
231 | Case 19 | Important Radiologic | HR(+) HER2(-) Breast Cancer | Important Radiologic. Findings. See Figs. 101, 102, 103, 104 and 105.. 19.3. |
237 | Case 19 | Patient History | HR(+) HER2(-) Breast Cancer | No comorbidities.. 19.2. |
224 | Case 19 | Courses of Treatment | HR(−) HER2(+) Breast Cancer | 19.1. . Operation. 140. Pathology Report. Invasive Ductal Carcinoma. 1. Size of tumor: 2.1 cm (pT2).. 2. Histologic grade: 3/3 (tubule formation: 3/3,. nuclear pleomorphism: 3/3, mitotic count:. 12/3, 2/10HPF).. 3. Intraductal component: present, extratumoral. (5%) (nuclear grade: high, necrosis: present,. architec... |
232 | Case 19 | Important Radiologic | HR(−) HER2(+) Breast Cancer | Important Radiologic. Findings. 136 137 138. 139 |
238 | Case 19 | Patient History | HR(−) HER2(+) Breast Cancer | Patient History and Progress. Female/52 years old, pre-menopause.. Self-detected palpable mass lesion on left. breast 1 and 2 o’clock direction.. No family history.. Hepatitis B virus carrier, liver cirrhosis.. Y. Kwon et al.. 505. 19.2. |
225 | Case 19 | Courses of Treatment | HR(−) HER2(−) Breast Cancer | 19.1. . Courses of Treatment. Operation + adjuvant chemotherapy (#4. cycles of doxorubicin and cyclophospha. mide + #3 cycles of paclitaxel-stop d/t drug-. induced. pneumonitis). +. Post-operative. radiation therapy.. Operation. 134. Pathology Report. Invasive Ductal Carcinoma. 1. Size of tumor: 2.2 cm (pT2).. 2.... |
233 | Case 19 | Important Radiologic | HR(−) HER2(−) Breast Cancer | Important Radiologic Findings. 131 132. 133. 19.3. |
239 | Case 19 | Patient History | HR(−) HER2(−) Breast Cancer | Patient History and Progress. Female/63 years old, post-menopause.. Screen detected mass lesion on right breast 10. o’clock direction.. No family history.. Hepatitis B virus carrier, h/o Tuberculosis.. 19.2. |
226 | Case 19 | Courses of Treatment | Local Recurrence | 19.1. . Courses of Treatment. Left breast IDC → Adjuvant therapy.. Primary Treatment. 133 134 135 136. 137. Neoadjuvant Chemotherapy. Neoadjuvant chemotherapy #4 cycles of doxoru. bicin and cyclophosphamide followed by. #4 cycles of docetaxel and trastuzumab.. Operation. . . 138. 139. Pathology Report. <Right>. Com... |
240 | Case 19 | Patient History | Local Recurrence | Patient History and Progress. Female/52 years old, pre-menopause.. Screen detected mass lesion on right breast. subareolar area and left breast subareolar area.. No family history.. Hypertension.. 19.2. |
227 | Case 19 | Courses of Treatment | Metastatic Breast Cancer | 19.1. . Courses of Treatment. Right breast cancer → Operation → Adjuvant. therapy → Ipsilateral axillary lymph node. recurrence → Operation → Endocrine therapy. → Progressive disease.. Primary Treatment. Positive %. Estrogen. receptor. Strong (7/8). 3. 1/3–2/3. Progesterone. receptor. Strong (7/8). 3. 1/3–2/3. C-erbB2... |
241 | Case 19 | Patient History | Metastatic Breast Cancer | Patient History and Progress. Female/45 years old, post-menopause.. No family history.. S/p bilateral salpingo-oophorectomy.. 19.2. |
242 | Case 2 | Courses of Treatment | Benign and Proliferative | 2.1. . Courses of Treatment. → 2022-02-14 Excision, Lt.. 2.3.1. . Pathology Report. • Breast, left, excision:. –. – Atypical ductal hyperplasia with micro. -. calcification.. –. – Intraductal papilloma with usual ductal. hyperplasia.. 3. |
250 | Case 2 | Important Radiologic | Benign and Proliferative | Important Radiologic. Findings. 3. 2.3. |
256 | Case 2 | Patient History | Benign and Proliferative | Patient History and Progress. Female/47 years old, pre-menopause.. Screen detected mass lesion on left breast. 2 o’clock direction.. Outside result of biopsy: Intraductal papilloma.. No family history.. No comorbidities.. 2.2. |
243 | Case 2 | Courses of Treatment | Carcinoma In Situ | 2.1. |
251 | Case 2 | Important Radiologic | Carcinoma In Situ | Important Radiologic. Findings. 7. 8. 2.3. . Course of Treatment:. Operation. 2.3.1. . Operation. 9. 10. 2.3.2. . Pathology Report. Lobular carcinoma in situ. . 1. Size of tumor: 0.2 cm2.. . 2. Nuclear grade: low.. . 3. Necrosis: absent.. . 4. Architectural pattern: solid.. . 5. Surgical margin: 2 mm from neare... |
257 | Case 2 | Patient History | Carcinoma In Situ | Patient History and Progress. Female/47 years old, pre-menopause.. Nipple discharge on left breast.. Family history of breast cancer, mother and. sister, aunt, cousin sister.. Thrombocytopenia (Follow-up at outside. hospital).. BRCA 2 VUS (variant of uncertain).. 2.2. |
244 | Case 2 | Courses of Treatment | HR(+) HER2(+) Breast Cancer | 2.1. . Courses of Treatment. Neoadjuvant chemotherapy (#6 cycles of. docetaxel and carboplatin and trastuzumab. and pertuzumab) + Operation + Post-. operative radiation therapy + Trastuzumab. emtansine + Tamoxifen 20 mg/day.. 12. 2.3.1. . Pathology Report. . 1. Microinvasive ductal carcinoma.. . (a) Post-che... |
252 | Case 2 | Important Radiologic | HR(+) HER2(+) Breast Cancer | Important Radiologic. Findings. 8 9 10. 11. 2.3. |
258 | Case 2 | Patient History | HR(+) HER2(+) Breast Cancer | Patient History and Progress. Female/42 years old, pre-menopause.. Screen detected mass lesion on left breast. 1:30 and 2 o’clock direction.. No family history.. S/P Cervical spine disc operation.. 2.2. |
245 | Case 2 | Courses of Treatment | HR(+) HER2(-) Breast Cancer | Courses of Treatment. Operation + Post-operative radiation ther. apy + Anastrozole 1 mg/day.. 2.3.1. . Operation. Left breast conserving surgery, sentinel lymph. low, necrosis: absent, architectural pattern:. cribriform, extensive intraductal component:. absent).. 4. Skin: no involvement of tumor.. 5. Surgical ma... |
253 | Case 2 | Important Radiologic | HR(+) HER2(-) Breast Cancer | Important Radiologic. Findings. See Figs. 5, 6, 7 and 8.. HR(+) HER2(−) Breast Cancer. 3. >2/3. C-erbB2. Negative (0). Ki-67. Positive in 5% of tumor cells. 2.3. |
259 | Case 2 | Patient History | HR(+) HER2(-) Breast Cancer | Hepatitis B virus carrier, dyslipidemia.. 2.2. |
246 | Case 2 | Courses of Treatment | HR(−) HER2(+) Breast Cancer | 2.1. . Courses of Treatment. Neoadjuvant chemotherapy (#2 cycles of. docetaxel and carboplatin and trastuzumab and. pertuzumab + #4 cycles of docetaxel and trastu. zumab and pertuzumab) + Operation + Post-. operative radiation therapy + Trastuzumab. emtansine.. 2.4.1. . Operation. 17. 2.4.2. . Pathology Repo... |
254 | Case 2 | Important Radiologic | HR(−) HER2(+) Breast Cancer | Important Radiologic Findings. 9 10 11. 434. 2.3. . After Neoadjuvant. Chemotherapy. 13 14 15. 16. . Y. Kwon et al.. 435. . . . . HR(−) HER2(+) Breast Cancer. 436. 2.4. |
260 | Case 2 | Patient History | HR(−) HER2(+) Breast Cancer | Patient History and Progress. Female/68 years old, post-menopause.. A self-detected skin change and nipple retrac. tion on left breast.. No family history.. Hypothyroidism.. 2.2. |
247 | Case 2 | Courses of Treatment | HR(−) HER2(−) Breast Cancer | 2.1. . Courses of Treatment. Neoadjuvant chemotherapy (#4 cycles of. doxorubicin and cyclophosphamide + #4. cycles of docetaxel) + Operation + Post-. operative radiation therapy.. 2.3.1. . Operation. 15. 2.3.2. . Pathology Report. No residual tumor with stromal fibrosis. . 1. Post-chemotherapy status.. . 2. Lymph... |
255 | Case 2 | Important Radiologic | HR(−) HER2(−) Breast Cancer | Important Radiologic. Findings. 8 9 10. 11. E. S. Lee et al.. 579. . . . HR(−) HER2(−) Breast Cancer. 580. . 2.2.1. . After Neoadjuvant. Chemotherapy. 12 13. 14. 2.3. |
261 | Case 2 | Patient History | HR(−) HER2(−) Breast Cancer | Patient History and Progress. Female/49 years old, pre-menopause.. Self-detected palpable mass lesion on right. breast.. No family history.. No comorbidities.. 2.2. |
248 | Case 2 | Courses of Treatment | Local Recurrence | 2.1. . Courses of Treatment. Left breast IDC → Operation → Adjuvant. . therapy → Left breast recurrence (IDC).. 2.2.1. . Primary Treatment. 10. Operation. Nov. 2008 Left breast conserving surgery, senti. nel lymph node biopsy (outside).. Pathology Report. Invasive Ductal Carcinoma. . 1. Size of tumor: 0.4 cm (pT1a)... |
262 | Case 2 | Patient History | Local Recurrence | Patient History and Progress. Female/54 years old, peri-menopause.. Screen detected mass lesion on left breast. . 2 o’clock direction.. No family history.. No comorbidities.. 2.2. |
249 | Case 2 | Courses of Treatment | Metastatic Breast Cancer | Courses of Treatment. Right breast cancer → Operation + Adjuvant. therapy → Lung metastasis → Palliative therapy. → Progression on rib and lung → Palliative. therapy → Progression on liver → Palliative. therapy.. 2.2.1. . Primary Treatment. Radiologic Finding. Estrogen. receptor. Strong (6/7). 2. >2/3. Progest... |
263 | Case 20 | Courses of Treatment | Benign and Proliferative | 20.1. . Courses of Treatment. →2021-05-10 excision, Lt.. Pathology Report. Diagnosis. • Breast, left, excision:. –. – Atypical ductal hyperplasia.. –. – Fibrocystic change with microcalcification.. 21. |
271 | Case 20 | Important Radiologic | Benign and Proliferative | Important Radiologic. Findings. 37. 38. . Benign and Proliferative Case Series. 42. . 20.3. |
277 | Case 20 | Patient History | Benign and Proliferative | Patient History and Progress. Female/44 years old, pre-menopause.. Screen detected microcalcification on upper. outer portion of left breast.. Family history of breast cancer, sister.. No comorbidities.. 20.2. |
264 | Case 20 | Courses of Treatment | Carcinoma In Situ | 20.1. . Courses of Treatment. First Operation + Tamoxifen 20 mg/day for. 4 months.. Second Operation.. Carcinoma In Situ. 96. . . . Operation. First operation: Breast conserving surgery, senti. nel lymph node biopsy (left).. Second operation: Skin sparing mastectomy. with latissimus dorsi flap reconstruction (left)... |
272 | Case 20 | Important Radiologic | Carcinoma In Situ | Important Radiologic. Findings. 91. 92. 20.3. |
278 | Case 20 | Patient History | Carcinoma In Situ | Patient History and Progress. Female/48 years old, pre-menopause.. Screen detected mass lesion on left breast 3. o’clock direction at first visit.. Pain on right breast at second visit.. No family history.. No comorbidities.. NGS: negative.. 20.2. |
265 | Case 20 | Courses of Treatment | HR(+) HER2(+) Breast Cancer | 20.1. . Courses of Treatment. Operation + Adjuvant chemotherapy (#4. cycles of doxorubicin and cyclophosphamide. followed by #11 cycles of weekly pacli. taxel). +. Post-operative. radiation. ther. apy + Trastuzumab + Letrozole 2.5 mg/day.. 110. Pathology Report. Invasive Ductal Carcinoma. 1. Post-mammotome excisi... |
273 | Case 20 | Important Radiologic | HR(+) HER2(+) Breast Cancer | Important Radiologic. Findings. 106 107 108. 109. 20.3. |
279 | Case 20 | Patient History | HR(+) HER2(+) Breast Cancer | Patient History and Progress. Female/75 years old, post-menopause.. Screen detected mass lesion on right breast 8. o’clock direction.. No family history.. Asthma (follow-up).. 20.2. |
266 | Case 20 | Courses of Treatment | HR(+) HER2(-) Breast Cancer | Courses of Treatment. Operation + Post-operative radiation ther. apy + Tamoxifen 20 mg/day.. Operation. Left breast conserving surgery, sentinel lymph. extensive intraductal component: present).. 4. Skin: no involvement of tumor.. 5. Surgical margins:. . (a) superior margin: 15 mm.. . (b) inferior margin: 20 mm.... |
274 | Case 20 | Important Radiologic | HR(+) HER2(-) Breast Cancer | Important Radiologic. Findings. See Figs. 108, 109, 110, 111 and 112.. 20.3. |
280 | Case 20 | Patient History | HR(+) HER2(-) Breast Cancer | o’clock direction.. No family history.. S/P Tuberculosis, S/P duodenal adenoma. excision.. 20.2. |
267 | Case 20 | Courses of Treatment | HR(−) HER2(+) Breast Cancer | 20.1. . Courses of Treatment. Neoadjuvant chemotherapy (#6 cycles of. docetaxel and carboplatin and trastuzumab and. pertuzumab) + Operation + Post-operative radia. tion therapy + Trastuzumab.. Operation. 147. Pathology Report. Invasive Ductal Carcinoma. 1. Post-chemotherapy status.. 2. Size of tumor: 1.1 cm (ypT1c... |
275 | Case 20 | Important Radiologic | HR(−) HER2(+) Breast Cancer | Important Radiologic. Findings. 141 142. 143. HR(−) HER2(+) Breast Cancer. 508. . . . Y. Kwon et al.. 509. 20.3. . After Neoadjuvant. Chemotherapy. 144 145. 146. . . . HR(−) HER2(+) Breast Cancer. 510. 20.4. |
281 | Case 20 | Patient History | HR(−) HER2(+) Breast Cancer | Patient History and Progress. Female/54 years old, post-menopause.. Screen detected mass lesion on left breast 11. o’clock direction.. Family history of breast cancer, aunt. (paternal).. No comorbidities.. BRCA 1 and 2 mutation: Not detected.. 20.2. |
268 | Case 20 | Courses of Treatment | HR(−) HER2(−) Breast Cancer | 20.1. . Courses of Treatment. Neoadjuvant chemotherapy (#4 cycles of. doxorubicin and cyclophosphamide + #4. cycles of docetaxel) + Operation + Post-. operative radiation therapy.. Operation. 143. Pathology Report. No residual tumor with stromal fibrosis. E. S. Lee et al.. 645. . . . HR(−) HER2(−) Breast Cancer... |
276 | Case 20 | Important Radiologic | HR(−) HER2(−) Breast Cancer | Important Radiologic. Findings. 135 136 137. 138. E. S. Lee et al.. 643. . . . . HR(−) HER2(−) Breast Cancer. 644. . After Neoadjuvant. Chemotherapy. 139 140 141. 142. 20.3. |
282 | Case 20 | Patient History | HR(−) HER2(−) Breast Cancer | Patient History and Progress. Female/59 years old, post-menopause.. Screen detected mass lesion on left breast 9:30. o’clock direction.. Family history of breast cancer, aunt. (maternal).. No comorbidities.. BRCA 1 and 2 mutation: Not detected.. 20.2. |
269 | Case 20 | Courses of Treatment | Local Recurrence | 20.1. . Courses of Treatment. Right breast DCIS → Operation → Adjuvant. therapy → Right breast recurrence (microinva. sive ductal carcinoma).. Primary Treatment. 140. Operation. Jul. 2017 Right breast conserving surgery, senti. nel lymph node biopsy (outside).. Pathology Report. Ductal Carcinoma In Situ. 1. Size of... |
283 | Case 20 | Patient History | Local Recurrence | Patient History and Progress. Female/41 years old, pre-menopause.. Screen detected mass lesion on right breast 12. o’clock direction.. Outside result of biopsy: Ductal carcinoma in. situ.. No family history.. s/p Right breast conserving surgery (Breast. cancer), s/p parotidectomy, Panic disorder.. BRCA 1 VUS (variant o... |
270 | Case 20 | Courses of Treatment | Metastatic Breast Cancer | Courses of Treatment. Left breast cancer → Operation → Adjuvant. therapy → Ipsilateral axillary lymph node. recurrence.. Primary Treatment. Operation. Sep. 1998 Left breast conserving surgery, axil. lary lymph node dissection.. Pathology: Invasive ductal carcinoma, stage. pT1aN0.. Size of tumor: N.A, lymph node: 0/16.... |
284 | Case 20 | Patient History | Metastatic Breast Cancer | Family history of breast cancer, maternal. cousin.. BRCA 1 & 2 mutation: Not detected.. 20.2. |
285 | Case 21 | Courses of Treatment | Benign and Proliferative | 21.1. . Courses of Treatment. →2021-07-07 excision, both.. Pathology Report. Diagnosis. • Breast, left, excision:. –. – Intraductal papilloma.. –. – Sclerosing. adenosis. with. microcal-. cification.. Diagnosis. • Breast, right, excision:. –. – Intraductal papilloma.. –. – Sclerosing adenosis with microcalcification... |
293 | Case 21 | Important Radiologic | Benign and Proliferative | Important Radiologic. Findings. 39 40. 41. 21.3. |
299 | Case 21 | Patient History | Benign and Proliferative | Patient History and Progress. Female/42 years old, pre-menopause.. Screen detected mass lesion on right breast 7. o’clock direction and left 1 o’clock direction.. Outside result of biopsy: both papillary. neoplasm.. No family history.. s/p Right breast mammotome biopsy (result:. fibroadenoma).. 21.2. |
286 | Case 21 | Courses of Treatment | Carcinoma In Situ | 21.1. . Courses of Treatment. Operation + Postoperative radiation therapy +. Tamoxifen 20 mg/day for 5 years.. . . E. S. Lee et al.. 99. Operation. 98. 99. Pathology Report. Ductal carcinoma in situ, pathological TN cat. egory (AJCC 2017): pTisN0 (sn). . 1. Size of tumor: 3.0 cm (pTis).. . 2. Nuclear grade: low.. .... |
294 | Case 21 | Important Radiologic | Carcinoma In Situ | Important Radiologic. Findings. 95 96. 97. 21.3. |
300 | Case 21 | Patient History | Carcinoma In Situ | Patient History and Progress. Female/37 years old, pre-menopause.. Screen detected mass lesion on right breast. 9 o’clock direction.. Outside result of biopsy: Right 9 o’clock, duc. tal carcinoma in situ.. No family history.. Thyroid papillary carcinoma: follow-up at. outside hospital.. BRCA 1 and 2: not detected, POL... |
287 | Case 21 | Courses of Treatment | HR(+) HER2(+) Breast Cancer | 21.1. . Courses of Treatment. Neoadjuvant chemotherapy (#6 cycles of. docetaxel and carboplatin and trastuzumab. and pertuzumab) + Operation + Post-. operative radiation therapy + Letrozole. 2.5 mg/day.. 117. Pathology Report. Invasive Ductal Carcinoma. 1. Post-chemotherapy status.. 2. Size of tumor: 1.1 cm (... |
295 | Case 21 | Important Radiologic | HR(+) HER2(+) Breast Cancer | Important Radiologic. Findings. 111 112 113 114 115. 116. 21.3. |
301 | Case 21 | Patient History | HR(+) HER2(+) Breast Cancer | Patient History and Progress. Female/69 years old, post-menopause.. Screen detected mass lesion on right breast 6. o’clock direction.. Family history of breast cancer, paternal aunt,. cousin (paternal).. No comorbidities.. BRCA 1 and 2 mutation: Not detected.. 21.2. |
288 | Case 21 | Courses of Treatment | HR(+) HER2(-) Breast Cancer | 21.1. . Courses of Treatment. Operation + Post-operative radiation ther. apy + Letrozole 2.5 mg/day.. Operation (1st, Dec. 2020). nent: absent).. 4. Skin: no involvement of tumor.. 5. Surgical margins:. . (a) superior margin: 5 mm.. . (b) inferior margin: 20 mm.. . (c) medial margin: 10 mm.. . (d) lateral mar... |
296 | Case 21 | Important Radiologic | HR(+) HER2(-) Breast Cancer | Important Radiologic. Findings. See Figs. 114, 115, 116 and 117.. 21.3. |
302 | Case 21 | Patient History | HR(+) HER2(-) Breast Cancer | Patient History and Progress. Female/78 years old, post-menopause.. Screen detected mass lesion on left breast 12. o’clock direction.. No family history.. Hypertension, s/p hysterectomy.. 21.2. |
289 | Case 21 | Courses of Treatment | HR(−) HER2(+) Breast Cancer | 21.1. . Operation. 156. Pathology Report. Invasive Ductal Carcinoma. 1. Post-chemotherapy status.. 2. Size of tumor: 1.0 cm (ypT1b).. 3. Histologic grade: 3/3 (tubule formation: 2/3,. nuclear pleomorphism: 3/3, mitotic count:. 3/3, 49/10HPF).. 4. Intraductal component: absent.. Y. Kwon et al.. 515. a. b. . 5. Sur... |
297 | Case 21 | Important Radiologic | HR(−) HER2(+) Breast Cancer | Important Radiologic. Findings. 148 149 150. 151. . HR(−) HER2(+) Breast Cancer. 512. . . . . Y. Kwon et al.. 513. 21.3. . After Neoadjuvant. Chemotherapy. 152 153 154. 155. . HR(−) HER2(+) Breast Cancer |
303 | Case 21 | Patient History | HR(−) HER2(+) Breast Cancer | Patient History and Progress. Female/55 years old, pre-menopause.. Self-detected palpable mass lesion on right. breast.. No family history.. S/P Tuberculosis.. 21.2. |
290 | Case 21 | Courses of Treatment | HR(−) HER2(−) Breast Cancer | 21.1. . Courses of Treatment. Neoadjuvant chemotherapy (#4 cycles of. doxorubicin and cyclophosphamide + #4. cycles of docetaxel) + Operation + Post-. operative radiation therapy + Letrozole. 2.5 mg + Adjuvant capecitabine.. Operation. 152. Pathology Report. Microinvasive Ductal Carcinoma. 1. Post-chemothera... |
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