id stringlengths 40 40 | source stringclasses 9
values | title stringlengths 2 345 | clean_text stringlengths 35 1.63M | raw_text stringlengths 4 1.63M | url stringlengths 4 498 | overview stringlengths 0 10k |
|---|---|---|---|---|---|---|
a3b5bbd91bd6853c82f206e405458c19a5ac4f5f | wikidoc | CARM1 | CARM1
CARM1 (coactivator-associated arginine methyltransferase 1), also known as PRMT4 (protein arginine N-methyltransferase 4), is an enzyme (EC 2.1.1.125) encoded by the CARM1 gene found in human beings, as well as many other mammals. It has a polypeptide (L) chain type that is 348 residues long, and is made up of al... | CARM1
CARM1 (coactivator-associated arginine methyltransferase 1), also known as PRMT4 (protein arginine N-methyltransferase 4), is an enzyme (EC 2.1.1.125) encoded by the CARM1 gene found in human beings, as well as many other mammals.[2] It has a polypeptide (L) chain type that is 348 residues long, and is made up o... | https://www.wikidoc.org/index.php/CARM1 | |
eb4a80793e2e234086608387359b7f3a9739dc17 | wikidoc | CASC5 | CASC5
CASC5 is a protein that is encoded by the CASC5 gene in humans.
# Function
CASC5 is part of the kinetochore. It is involved in microtubule attachment to chromosome centromeres and in the activation of the spindle checkpoint during mitosis. The CASC5 gene is upregulated in the areas of cell proliferation surround... | CASC5
CASC5 is a protein that is encoded by the CASC5 gene in humans.[1][2][3][4]
# Function
CASC5 is part of the kinetochore. It is involved in microtubule attachment to chromosome centromeres and in the activation of the spindle checkpoint during mitosis. The CASC5 gene is upregulated in the areas of cell prolifera... | https://www.wikidoc.org/index.php/CASC5 | |
4dcb18914b5cf92048609b3ff7a7ce10a13f0230 | wikidoc | CASPR | CASPR
CASPR also known as Contactin associated protein 1, Paranodin and CASPR1 is a protein that in humans is encoded by the CNTNAP1 gene.
CASPR is a part of the neurexin family of proteins, hence its another name "Neurexin IV". CASPR is a membrane protein found in the neuronal membrane in the paranodal section of the ... | CASPR
CASPR also known as Contactin associated protein 1, Paranodin and CASPR1 is a protein that in humans is encoded by the CNTNAP1 gene.[1]
CASPR is a part of the neurexin family of proteins, hence its another name "Neurexin IV".[2] CASPR is a membrane protein found in the neuronal membrane in the paranodal section ... | https://www.wikidoc.org/index.php/CASPR | |
6c8ee61e4415505c120d5b165d6c73ec77170802 | wikidoc | CASS4 | CASS4
Cas scaffolding protein family member 4 is a protein that in humans is encoded by the CASS4 gene.
# History and discovery
CASS4 (Crk associated substrate 4) is the fourth and last described member of the CAS protein family. CASS4 was detected by Singh et al. in 2008 following in silico screening of databases des... | CASS4
Cas scaffolding protein family member 4 is a protein that in humans is encoded by the CASS4 gene.[1]
# History and discovery
CASS4 (Crk associated substrate 4) is the fourth and last described member of the CAS protein family.[2] CASS4 was detected by Singh et al.[3] in 2008 following in silico screening of dat... | https://www.wikidoc.org/index.php/CASS4 | |
6b4be5a9a3aa482c5c9dbe5529ddb661bbf6f7e5 | wikidoc | CCBE1 | CCBE1
Collagen and calcium-binding EGF domain-containing protein 1 is a protein that in humans is encoded by the CCBE1 gene.
# Function
CCBE1 is a regulator of the development and growth of the lymphatic system. CCBE1 is necessary for the proteolytic activation of VEGF-C by ADAMTS3, which is the main growth factor for... | CCBE1
Collagen and calcium-binding EGF domain-containing protein 1 is a protein that in humans is encoded by the CCBE1 gene.[1][2]
# Function
CCBE1 is a regulator of the development and growth of the lymphatic system. CCBE1 is necessary for the proteolytic activation of VEGF-C by ADAMTS3[3], which is the main growth ... | https://www.wikidoc.org/index.php/CCBE1 | |
0d565f74b449608713b9adc26d17e79e26087ab6 | wikidoc | CCDC8 | CCDC8
Coiled-coil domain containing 8 is a protein that in humans is encoded by the CCDC8 gene.
# Function
This gene encodes a coiled coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interact... | CCDC8
Coiled-coil domain containing 8 is a protein that in humans is encoded by the CCDC8 gene.[1]
# Function
This gene encodes a coiled coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through inte... | https://www.wikidoc.org/index.php/CCDC8 | |
31b588a2dfa3584b57fdfc3d07515564b89e86de | wikidoc | CCL11 | CCL11
C-C motif chemokine 11 also known as eosinophil chemotactic protein and eotaxin-1 is a protein that in humans is encoded by the CCL11 gene. This gene is encoded on three exons and is located on chromosome 17.
# Function
CCL11 is a small cytokine belonging to the CC chemokine family. CCL11 selectively recruits eo... | CCL11
C-C motif chemokine 11 also known as eosinophil chemotactic protein and eotaxin-1 is a protein that in humans is encoded by the CCL11 gene. This gene is encoded on three exons and is located on chromosome 17.[1][2]
# Function
CCL11 is a small cytokine belonging to the CC chemokine family. CCL11 selectively recr... | https://www.wikidoc.org/index.php/CCL11 | |
35a8b928820d992b4b5cea611dda4c4c9724fe8b | wikidoc | CCL16 | CCL16
Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). This chemokine is expressed by the liver, thymus, and spleen and is chemoattractive for monocytes and lympho... | CCL16
Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). This chemokine is expressed by the liver, thymus, and spleen and is chemoattractive for monocytes and lymph... | https://www.wikidoc.org/index.php/CCL16 | |
659468b33a75be1f5bd486178839346013cb525f | wikidoc | CCL18 | CCL18
Chemokine (C-C motif) ligand 18 (CCL18) is a small cytokine belonging to the CC chemokine family. The functions of CCL18 have been well studied in laboratory settings, however the physiological effects of the molecule in living organisms have been difficult to characterize because there is no similar protein in r... | CCL18
Chemokine (C-C motif) ligand 18 (CCL18) is a small cytokine belonging to the CC chemokine family. The functions of CCL18 have been well studied in laboratory settings, however the physiological effects of the molecule in living organisms have been difficult to characterize because there is no similar protein in ... | https://www.wikidoc.org/index.php/CCL18 | |
cc2dc999fe0cf74cd380b1579306dddc8ed38c84 | wikidoc | CCL19 | CCL19
Chemokine (C-C motif) ligand 19 (CCL19) is a protein that in humans is encoded by the CCL19 gene.
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins... | CCL19
Chemokine (C-C motif) ligand 19 (CCL19) is a protein that in humans is encoded by the CCL19 gene.[1][2]
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are p... | https://www.wikidoc.org/index.php/CCL19 | |
d75abacbce7299b5bb2c92a83a2685481e4da01e | wikidoc | CCL20 | CCL20
Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils. CCL20 is implicated in the formation and funct... | CCL20
Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils.[1] CCL20 is implicated in the formation and f... | https://www.wikidoc.org/index.php/CCL20 | |
d8db52ccd390e1910fc63e78355d535ab7cceed1 | wikidoc | CCL24 | CCL24
Chemokine (C-C motif) ligand 24 (CCL24) also known as myeloid progenitor inhibitory factor 2 (MPIF-2) or eosinophil chemotactic protein 2 (eotaxin-2) is a protein that in humans is encoded by the CCL24 gene. This gene is located on human chromosome 7.
# Function
CCL24 is a small cytokine belonging to the CC chem... | CCL24
Chemokine (C-C motif) ligand 24 (CCL24) also known as myeloid progenitor inhibitory factor 2 (MPIF-2) or eosinophil chemotactic protein 2 (eotaxin-2) is a protein that in humans is encoded by the CCL24 gene.[1] This gene is located on human chromosome 7.[2]
# Function
CCL24 is a small cytokine belonging to the ... | https://www.wikidoc.org/index.php/CCL24 | |
8fd9134bb94a855abeb52fa446e14581a877e7c5 | wikidoc | CCL28 | CCL28
Chemokine (C-C motif) ligand 28 (CCL28), also known as mucosae-associated epithelial chemokine (MEC), CCK1 and SCYA28, is a chemokine. CCL28 regulates the chemotaxis of cells that express the chemokine receptors CCR3 and CCR10.
CCL28 is expressed by columnar epithelial cells in the gut, lung, breast and the saliv... | CCL28
Chemokine (C-C motif) ligand 28 (CCL28), also known as mucosae-associated epithelial chemokine (MEC), CCK1 and SCYA28, is a chemokine. CCL28 regulates the chemotaxis of cells that express the chemokine receptors CCR3 and CCR10.
CCL28 is expressed by columnar epithelial cells in the gut, lung, breast and the sali... | https://www.wikidoc.org/index.php/CCL28 | |
fd8dd7988a5501999dfe5557f0ef737729bcfd23 | wikidoc | CCR10 | CCR10
C-C chemokine receptor type 10 is a protein that in humans is encoded by the CCR10 gene.
# Function
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transm... | CCR10
C-C chemokine receptor type 10 is a protein that in humans is encoded by the CCR10 gene.[1][2]
# Function
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7... | https://www.wikidoc.org/index.php/CCR10 | |
a6bc87968f13a782ed600baa9aab2928f6fef047 | wikidoc | ITGAE | ITGAE
Integrin, alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) is an integrin protein that in human is encoded by the ITGAE gene. CD103 binds integrin beta 7 (β7– ITGB7) to form the complete heterodimeric integrin molecule αEβ7, which has no distinct name. The αEβ7 complex is often referred to as ... | ITGAE
Integrin, alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) is an integrin protein that in human is encoded by the ITGAE gene.[1][2] CD103 binds integrin beta 7 (β7– ITGB7) to form the complete heterodimeric integrin molecule αEβ7, which has no distinct name. The αEβ7 complex is often referred... | https://www.wikidoc.org/index.php/CD103 | |
0616342ed88d6f22bae39ea94627efb57bff0759 | wikidoc | LAMP2 | LAMP2
Lysosome-associated membrane protein 2 (LAMP2) also known as CD107b (Cluster of Differentiation 107b), is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins.
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides sele... | LAMP2
Lysosome-associated membrane protein 2 (LAMP2) also known as CD107b (Cluster of Differentiation 107b), is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins.
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides sel... | https://www.wikidoc.org/index.php/CD107b | |
bb26d73691024432015974bc60100303c9a2b7d8 | wikidoc | CD11a | CD11a
Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a human gene which functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab.
# Function
ITGAL encodes the ... | CD11a
Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a human gene which functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab.
# Function
ITGAL encodes the... | https://www.wikidoc.org/index.php/CD11a | |
73fbb6bb2dd28d7e47a95b1f2f617cadab51867c | wikidoc | CD11c | CD11c
CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a gene that encodes for CD11c .
CD11c is an integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chai... | CD11c
CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a gene that encodes for CD11c .[1][2]
CD11c is an integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta... | https://www.wikidoc.org/index.php/CD11c | |
4a70b0ae58a7f214110b6e34ccf42e59da89c9fe | wikidoc | CD120 | CD120
CD120 (Cluster of Differentiation 120) can refer to two members of the tumor necrosis factor receptor superfamily: tumor necrosis factor receptor 1 (TNFR1) and tumor necrosis factor receptor 2 (TNFR2).
# Receptor subtypes
There are two variants of the receptor, each encoded by a separate gene:
- CD120a - TNFR1 -... | CD120
CD120 (Cluster of Differentiation 120) can refer to two members of the tumor necrosis factor receptor superfamily: tumor necrosis factor receptor 1 (TNFR1) and tumor necrosis factor receptor 2 (TNFR2).[1][2]
# Receptor subtypes
There are two variants of the receptor, each encoded by a separate gene:
- CD120a - ... | https://www.wikidoc.org/index.php/CD120 | |
7c6b5909901df543faf22b2f1fa9a410e78139ea | wikidoc | CD133 | CD133
CD133 antigen, also known as prominin-1, is a glycoprotein that in humans is encoded by the PROM1 gene. It is a member of pentaspan transmembrane glycoproteins, which specifically localize to cellular protrusions. When embedded in the cell membrane, the membrane topology of prominin-1 is such that the N-terminus ... | CD133
CD133 antigen, also known as prominin-1, is a glycoprotein that in humans is encoded by the PROM1 gene.[1][2] It is a member of pentaspan transmembrane glycoproteins, which specifically localize to cellular protrusions. When embedded in the cell membrane, the membrane topology of prominin-1 is such that the N-te... | https://www.wikidoc.org/index.php/CD133 | |
b7d320e6693747f4aec649e41942f57e6ffd4223 | wikidoc | CD134 | CD134
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor, is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to ... | CD134
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor, is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to... | https://www.wikidoc.org/index.php/CD134 | |
5b388959558f905bd3358851587b5a5a34a5788e | wikidoc | CD135 | CD135
Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. ... | CD135
Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III.... | https://www.wikidoc.org/index.php/CD135 | |
6e764fcc9b8f84e651d2341ac3d35c8cf3b40e98 | wikidoc | CD137 | CD137
CD137 is a member of the tumor necrosis factor (TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9 (TNFRSF9), 4-1BB and induced by lymphocyte activation (ILA). It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule.
# Expressio... | CD137
CD137 is a member of the tumor necrosis factor (TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9 (TNFRSF9), 4-1BB and induced by lymphocyte activation (ILA). It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule.
# Expressi... | https://www.wikidoc.org/index.php/CD137 | |
6b5635694e5e66692a06c5c135bf0766efe0f6f3 | wikidoc | CD146 | CD146
CD146 (cluster of differentiation 146) also known as the melanoma cell adhesion molecule (MCAM) or cell surface glycoprotein MUC18, is a 113kDa cell adhesion molecule currently used as a marker for endothelial cell lineage. In humans, the CD146 protein is encoded by the MCAM gene.
# Function
MCAM functions as a... | CD146
CD146 (cluster of differentiation 146) also known as the melanoma cell adhesion molecule (MCAM) or cell surface glycoprotein MUC18, is a 113kDa cell adhesion molecule currently used as a marker for endothelial cell lineage. In humans, the CD146 protein is encoded by the MCAM gene.[1]
# Function
MCAM functions ... | https://www.wikidoc.org/index.php/CD146 | |
e3c9225ee409713d3f0bd217665dcd635c0850f3 | wikidoc | CD154 | CD154
CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding... | CD154
CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells[1] and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three bin... | https://www.wikidoc.org/index.php/CD154 | |
a0307acb17120f3a2f088b43ed9aa9afddec46b7 | wikidoc | CD155 | CD155
CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene.
# Function
CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliov... | CD155
CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene.[1][2]
# Function
CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily.[3] Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellu... | https://www.wikidoc.org/index.php/CD155 | |
44fce36aabe8f6babacba7ed5eaeb6d5a0216d7d | wikidoc | CD160 | CD160
CD160 antigen is a protein that in humans is encoded by the CD160 gene.
CD160 is a 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of ... | CD160
CD160 antigen is a protein that in humans is encoded by the CD160 gene.[1][2][3]
CD160 is a 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA se... | https://www.wikidoc.org/index.php/CD160 | |
43ad0597d64c43b790cdcd83441fc1f5b30d273a | wikidoc | CD163 | CD163
CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene. CD163 is the high affinity scavenger receptor for the hemoglobin-haptoglobin complex and in the absence of haptoglobin - with lower affinity - for hemoglobin alone. It also is a marker of cells from the monocyte/macro... | CD163
CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene.[1] CD163 is the high affinity scavenger receptor for the hemoglobin-haptoglobin complex[2] and in the absence of haptoglobin - with lower affinity - for hemoglobin alone.[3] It also is a marker of cells from the mono... | https://www.wikidoc.org/index.php/CD163 | |
a29dc64e817d1f66304616d141fd8af749c75141 | wikidoc | CD226 | CD226
CD226 (Cluster of Differentiation 226), PTA1 (outdated term, 'platelet and T cell activation antigen 1') or DNAM-1 (DNAX Accessory Molecule-1) is a protein that in humans is encoded by the CD226 gene which is located on chromosome 18q22.3.
# Structure and function
CD226 is a ~65 kDa glycoprotein expressed on the... | CD226
CD226 (Cluster of Differentiation 226), PTA1 (outdated term, 'platelet and T cell activation antigen 1')[1] or DNAM-1 (DNAX Accessory Molecule-1)[1] is a protein that in humans is encoded by the CD226 gene which is located on chromosome 18q22.3.[2]
# Structure and function
CD226 is a ~65 kDa glycoprotein expres... | https://www.wikidoc.org/index.php/CD226 | |
dc1348fb7cbd40afcff4b9b4c4cd87a75df03734 | wikidoc | CD244 | CD244
CD244 (Cluster of Differentiation 244) is a human protein encoded by the CD244 gene. It is also known as Natural Killer Cell Receptor 2B4
This gene encodes a cell surface receptor expressed on natural killer cells (NK cells) (and some T cells) mediating non-major histocompatibility complex (MHC) restricted killin... | CD244
CD244 (Cluster of Differentiation 244) is a human protein encoded by the CD244 gene.[1] It is also known as Natural Killer Cell Receptor 2B4[2]
This gene encodes a cell surface receptor expressed on natural killer cells (NK cells) (and some T cells) mediating non-major histocompatibility complex (MHC) restricted... | https://www.wikidoc.org/index.php/CD244 | |
182ff67ff68841a232136757e829ac091d03398a | wikidoc | CD247 | CD247
T-cell surface glycoprotein CD3 zeta chain also known as T-cell receptor T3 zeta chain or CD247 (Cluster of Differentiation 247) is a protein that in humans is encoded by the CD247 gene.
# Genomics
The gene is located on the long arm of chromosome 1 at location 1q22-q25 on the Crick (negative) strand. The gene ... | CD247
T-cell surface glycoprotein CD3 zeta chain also known as T-cell receptor T3 zeta chain or CD247 (Cluster of Differentiation 247) is a protein that in humans is encoded by the CD247 gene.[1]
# Genomics
The gene is located on the long arm of chromosome 1 at location 1q22-q25 on the Crick (negative) strand. The g... | https://www.wikidoc.org/index.php/CD247 | |
4d8aea8895b778550530cad209d6f5b6b6ff73dd | wikidoc | CD248 | CD248
Endosialin is a protein that in humans is encoded by the CD248 gene.
Endosialin is a member of the “Group XIV”, a novel family of C-type lectin transmembrane receptors which play a role not only in cell–cell adhesion processes but also in host defence. This family comprise two other members, CD93 and Thrombomodul... | CD248
Endosialin is a protein that in humans is encoded by the CD248 gene.[1][2][3]
Endosialin is a member of the “Group XIV”, a novel family of C-type lectin transmembrane receptors which play a role not only in cell–cell adhesion processes but also in host defence. This family comprise two other members, CD93 and Th... | https://www.wikidoc.org/index.php/CD248 | |
c50ad12ff8ff4be56917af254a533cc7b0fa687e | wikidoc | CD276 | CD276
CD276 (Cluster of Differentiation 276) is a human protein encoded by the CD276 gene.
# Function
Costimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558).
CD276 (aka B7-H3), an immune checkpoint molecule,... | CD276
CD276 (Cluster of Differentiation 276) is a human protein encoded by the CD276 gene.[1]
# Function
Costimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558).[supplied by OMIM][1]
CD276 (aka B7-H3), an im... | https://www.wikidoc.org/index.php/CD276 | |
5ebc138720d5b267063e2d0e8946dd829fae4aad | wikidoc | CD278 | CD278
Inducible T-cell costimulator is an immune checkpoint protein that in humans is encoded by the ICOS gene.
CD278 or ICOS (Inducible T-cell COStimulator) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells. It is thought to be important for Th2 cells in particular.
# Function
The pr... | CD278
Inducible T-cell costimulator is an immune checkpoint protein that in humans is encoded by the ICOS gene.[1][2][3]
CD278 or ICOS (Inducible T-cell COStimulator) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells. It is thought to be important for Th2 cells in particular.[4][5]
#... | https://www.wikidoc.org/index.php/CD278 | |
40c7b3e67a123b9825b521ba714e33786f847042 | wikidoc | CD49b | CD49b
Integrin alpha-2 or CD49b (cluster of differentiation 49b) is a protein which in humans is encoded by the CD49b gene.
The CD49b protein is an integrin alpha subunit. It makes up half of the α2β1 integrin duplex. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a c... | CD49b
Integrin alpha-2 or CD49b (cluster of differentiation 49b) is a protein which in humans is encoded by the CD49b gene.
The CD49b protein is an integrin alpha subunit. It makes up half of the α2β1 integrin duplex. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a ... | https://www.wikidoc.org/index.php/CD49b | |
a00bb7a9524dcb99c975ccb7d42f8be9f6ac55b8 | wikidoc | CD49c | CD49c
Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene.
ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes up half of the α3β1 integrin duplex that plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin.
ITGA3 encodes the i... | CD49c
Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene.[1][2]
ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes up half of the α3β1 integrin duplex that plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin.
ITGA3 encode... | https://www.wikidoc.org/index.php/CD49c | |
c75f86ad541ae27ea27f0c06cf2247fec9680e96 | wikidoc | CD79A | CD79A
Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene.
The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglob... | CD79A
Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene.[1]
The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immuno... | https://www.wikidoc.org/index.php/CD79A | |
6ff3993d4f404267c5557656f57d5a82e42982d9 | wikidoc | CDC20 | CDC20
The cell-division cycle protein 20 is an essential regulator of cell division that is encoded by the CDC20 gene in humans. To the best of current knowledge its most important function is to activate the anaphase promoting complex (APC/C), a large 11-13 subunit complex that initiates chromatid separation and entra... | CDC20
The cell-division cycle protein 20 is an essential regulator of cell division that is encoded by the CDC20 gene[1][2] in humans. To the best of current knowledge its most important function is to activate the anaphase promoting complex (APC/C), a large 11-13 subunit complex that initiates chromatid separation an... | https://www.wikidoc.org/index.php/CDC20 | |
ce6394642aff4577c1164d1f0dfd99160977c411 | wikidoc | CDC34 | CDC34
CDC34 is a gene encoding a protein product that has ubiquitin conjugating activity. CDC34 was originally discovered by work in baker's yeast as a gene that has a role in the cell division cycle. Cdc34 in yeast targets numerous substrates (Sic1, Far1, Cln1, Cln2) for ubiquitin mediated degradation.
Ubiquitin-conj... | CDC34
CDC34 is a gene encoding a protein product that has ubiquitin conjugating activity. CDC34 was originally discovered by work in baker's yeast as a gene that has a role in the cell division cycle. Cdc34 in yeast targets numerous substrates (Sic1, Far1, Cln1, Cln2) for ubiquitin mediated degradation.
Ubiquitin-con... | https://www.wikidoc.org/index.php/CDC34 | |
92dd85c960a88bcce0d8b0c3b64d9a52c1056575 | wikidoc | CDC37 | CDC37
Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene.
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been ... | CDC37
Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene.[1][2]
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It ha... | https://www.wikidoc.org/index.php/CDC37 | |
b4acd341d5965d3bca6f2fd0a7f8c9e67cbb7db4 | wikidoc | CDC42 | CDC42
Cell division control protein 42 homolog, also known as Cdc42, is a protein involved in regulation of the cell cycle. It was originally identified in S. cerevisiae (yeast) as a mediator of cell division, and is now known to influence a variety of signaling events and cellular processes in a variety of organisms f... | CDC42
Cell division control protein 42 homolog, also known as Cdc42, is a protein involved in regulation of the cell cycle. It was originally identified in S. cerevisiae (yeast) as a mediator of cell division, and is now known to influence a variety of signaling events and cellular processes in a variety of organisms ... | https://www.wikidoc.org/index.php/CDC42 | |
e95b2b44a83f93f1e76034fde396991780c502de | wikidoc | CDC73 | CDC73
Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae), also known as CDC73 and parafibromin, is a protein which in humans is encoded by the CDC73 gene.
# Function
Parafibromin, LEO1, PAF1, and CTR9 form the PAF protein complex, which associates with the RNA polymerase II subun... | CDC73
Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae), also known as CDC73 and parafibromin, is a protein which in humans is encoded by the CDC73 gene.[1][2][3]
# Function
Parafibromin, LEO1, PAF1, and CTR9 form the PAF protein complex, which associates with the RNA polymeras... | https://www.wikidoc.org/index.php/CDC73 | |
71ac6136c8544b06cf0658f4cd081237684db50e | wikidoc | CDCA5 | CDCA5
Sororin is a protein that in humans is encoded by the CDCA5 gene.
# Function
Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.
# Clinical significance
Transactivation of Sororin and its phosphorylation at Ser209 by ERK play an important role in lung ... | CDCA5
Sororin is a protein that in humans is encoded by the CDCA5 gene.[1][2][3]
# Function
Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.[4]
# Clinical significance
Transactivation of Sororin and its phosphorylation at Ser209 by ERK play an important ... | https://www.wikidoc.org/index.php/CDCA5 | |
df17a4eb54f3a74321bda0342ef60e06f8bdfd4d | wikidoc | CDCA8 | CDCA8
Borealin is a protein that in humans is encoded by the CDCA8 gene.
# Function
CDCA8 is a component of a chromosomal passenger complex required for stability of the bipolar mitotic spindle.
# Interactions
CDCA8 has been shown to interact with INCENP, Survivin and Aurora B kinase. | CDCA8
Borealin is a protein that in humans is encoded by the CDCA8 gene.[1][2][3]
# Function
CDCA8 is a component of a chromosomal passenger complex required for stability of the bipolar mitotic spindle.[3][4]
# Interactions
CDCA8 has been shown to interact with INCENP,[4] Survivin[2][4] and Aurora B kinase.[2][4] | https://www.wikidoc.org/index.php/CDCA8 | |
2d45736d486403e7b49dae15285998d580a89cbb | wikidoc | CDCP1 | CDCP1
CUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. CDCP1 has also been designated as CD318 (cluster of differentiation 318) and Trask (Transmembrane and associated with src kinases). Alternatively spliced transcript variants encoding distinct isoforms have been repor... | CDCP1
CUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene.[1][2] CDCP1 has also been designated as CD318 (cluster of differentiation 318) and Trask (Transmembrane and associated with src kinases). Alternatively spliced transcript variants encoding distinct isoforms have bee... | https://www.wikidoc.org/index.php/CDCP1 | |
4161ab82806396b64ef9ee3005db972e9db4b7fb | wikidoc | CDCa1 | CDCa1
CDCa1 is a protein product of the human genome. The gene that codes for this protein is found on chromosome 1, from 150,076,963-150,079,657. The gene contains 2 exons and encodes 353 amino acids. Synonyms for CDCa1 are "hypothetical protein LOC100191040" and NP_001129475. CDCa1 contains a conserved metal bindi... | CDCa1
CDCa1 is a protein product of the human genome. The gene that codes for this protein is found on chromosome 1, from 150,076,963-150,079,657. The gene contains 2 exons and encodes 353 amino acids. Synonyms for CDCa1 are "hypothetical protein LOC100191040"[1] and NP_001129475. CDCa1 contains a conserved metal b... | https://www.wikidoc.org/index.php/CDCa1 | |
87dec77254fd12b0d33f7ef7d9efebb6a08aa5ff | wikidoc | CDEPT | CDEPT
# Overview
Clostridial-directed enzyme prodrug therapy (CDEPT) is the use of Clostridia to convert prodrugs into active drug agents. It is comparable to a more popular strategy, called ADEPT.
# The CDEPT strategy
Perhaps the most challenging issue in cancer treatment is how to reduce the side effects of the inj... | CDEPT
# Overview
Clostridial-directed enzyme prodrug therapy (CDEPT) is the use of Clostridia to convert prodrugs into active drug agents. It is comparable to a more popular strategy, called ADEPT.[1]
# The CDEPT strategy
Perhaps the most challenging issue in cancer treatment is how to reduce the side effects of the ... | https://www.wikidoc.org/index.php/CDEPT | |
b751eed37a0dc17ceeecc418b9a9e0a950aa3d4b | wikidoc | CDH11 | CDH11
Cadherin-11 is a protein that in humans is encoded by the CDH11 gene.
# Function
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular do... | CDH11
Cadherin-11 is a protein that in humans is encoded by the CDH11 gene.[1][2]
# Function
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracell... | https://www.wikidoc.org/index.php/CDH11 | |
c8bfe2344b58d50dbdae30a08b2c5a9ffe9fbeb5 | wikidoc | CDH23 | CDH23
Cadherin-23 is a protein that in humans is encoded by the CDH23 gene.
# Function
This gene is a member of the cadherin superfamily, genes encoding calcium dependent cell-cell adhesion glycoproteins. The protein encoded by this gene is a large, single-pass transmembrane protein composed of an extracellular domain... | CDH23
Cadherin-23 is a protein that in humans is encoded by the CDH23 gene.[1][2][3]
# Function
This gene is a member of the cadherin superfamily, genes encoding calcium dependent cell-cell adhesion glycoproteins. The protein encoded by this gene is a large, single-pass transmembrane protein composed of an extracellu... | https://www.wikidoc.org/index.php/CDH23 | |
605424153bd4f1a2a8bc942b02377f7876b58c31 | wikidoc | CDKL5 | CDKL5
CDKL5 is a gene that provides instructions for making a protein called cyclin-dependent kinase-like 5 also known as serine/threonine kinase 9 (STK9) that is essential for normal brain development with mutations causing deficiencies in the protein level. It regulates neuronal morphology through cytoplasmic signali... | CDKL5
CDKL5 is a gene that provides instructions for making a protein called cyclin-dependent kinase-like 5 also known as serine/threonine kinase 9 (STK9) that is essential for normal brain development with mutations causing deficiencies in the protein level. It regulates neuronal morphology through cytoplasmic signal... | https://www.wikidoc.org/index.php/CDKL5 | |
ec3271ad2bc2ad2fee419e3788d887e9bea1fa4a | wikidoc | CDKN3 | CDKN3
Cyclin-dependent kinase inhibitor 3 is an enzyme that in humans is encoded by the CDKN3 gene.
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase,... | CDKN3
Cyclin-dependent kinase inhibitor 3 is an enzyme that in humans is encoded by the CDKN3 gene.[1][2][3]
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CD... | https://www.wikidoc.org/index.php/CDKN3 | |
c062f39a8f1636222a078b11b8ef65f83f5971d3 | wikidoc | CEBPA | CEBPA
CCAAT/enhancer-binding protein alpha is a protein encoded by the CEBPA gene in humans. CCAAT/enhancer-binding protein alpha is a transcription factor involved in the differentiation of certain blood cells. For details on the CCAAT structural motif in gene enhancers and on CCAAT/Enhancer Binding Proteins see the s... | CEBPA
CCAAT/enhancer-binding protein alpha is a protein encoded by the CEBPA gene in humans.[1][2] CCAAT/enhancer-binding protein alpha is a transcription factor involved in the differentiation of certain blood cells.[3] For details on the CCAAT structural motif in gene enhancers and on CCAAT/Enhancer Binding Proteins... | https://www.wikidoc.org/index.php/CEBPA | |
acd9434da22cfedfe8e25847e0aeb2f182162b07 | wikidoc | CEBPB | CEBPB
CCAAT/enhancer-binding protein beta is a protein that in humans is encoded by the CEBPB gene.
# Function
The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, C... | CEBPB
CCAAT/enhancer-binding protein beta is a protein that in humans is encoded by the CEBPB gene.[1][2]
# Function
The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-a... | https://www.wikidoc.org/index.php/CEBPB | |
1a34a4d65c19931b339be2812ae1cb0cfd7a6331 | wikidoc | CEBPD | CEBPD
CCAAT/enhancer-binding protein delta is a protein that in humans is encoded by the CEBPD gene.
# Function
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. ... | CEBPD
CCAAT/enhancer-binding protein delta is a protein that in humans is encoded by the CEBPD gene.[1][2]
# Function
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-... | https://www.wikidoc.org/index.php/CEBPD | |
3ebfbea15be28b08375d51246605dce89464e107 | wikidoc | CENPA | CENPA
Centromere protein A, also known as CENPA, is a protein which in humans is encoded by the CENPA gene.
# Function
Centromeres are the chromosomal domains that specify the mitotic behavior of chromosomes. The CENPA gene encodes a centromere protein which contains a histone H3 related histone fold domain that is re... | CENPA
Centromere protein A, also known as CENPA, is a protein which in humans is encoded by the CENPA gene.[1]
# Function
Centromeres are the chromosomal domains that specify the mitotic behavior of chromosomes. The CENPA gene encodes a centromere protein which contains a histone H3 related histone fold domain that i... | https://www.wikidoc.org/index.php/CENPA | |
861000498ef4a79db816b87020f761e283f73078 | wikidoc | CENPH | CENPH
Centromere protein H is a protein that in humans is encoded by the CENPH gene.
# Function
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CE... | CENPH
Centromere protein H is a protein that in humans is encoded by the CENPH gene.[1][2][3]
# Function
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate p... | https://www.wikidoc.org/index.php/CENPH | |
1bd64a43a89b56b379ad20c63700dffb9229a68f | wikidoc | CENPJ | CENPJ
Centromere protein J is a protein that in humans is encoded by the CENPJ gene. It is also known as centrosomal P4.1-associated protein (CPAP).
During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disa... | CENPJ
Centromere protein J is a protein that in humans is encoded by the CENPJ gene.[1][2] It is also known as centrosomal P4.1-associated protein (CPAP).
During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubu... | https://www.wikidoc.org/index.php/CENPJ | |
bc3b2563fd069ed27e8319575e083f424908e38f | wikidoc | CEP63 | CEP63
Centrosomal protein of 63 kDa is a protein that in humans is encoded by the CEP63 gene. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.
# Function
This gene encodes a protein with six coiled-coil domains. The protein is localized to the ... | CEP63
Centrosomal protein of 63 kDa is a protein that in humans is encoded by the CEP63 gene.[1][2] Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.
# Function
This gene encodes a protein with six coiled-coil domains. The protein is localized ... | https://www.wikidoc.org/index.php/CEP63 | |
e1e410fdaf2ad5ada4549d3be2597e8e726be3c5 | wikidoc | CHD1L | CHD1L
Chromodomain-helicase-DNA-binding protein 1-like (ALC1) is an enzyme that in humans is encoded by the CHD1L gene. It has been implicated in chromatin remodeling and DNA relaxation process required for DNA replication, repair and transcription. The ALC1 comprises ATPase domain and macro domain. On the basis of hom... | CHD1L
Chromodomain-helicase-DNA-binding protein 1-like (ALC1) is an enzyme that in humans is encoded by the CHD1L gene.[1][2] It has been implicated in chromatin remodeling and DNA relaxation process required for DNA replication, repair and transcription. The ALC1 comprises ATPase domain and macro domain. On the basis... | https://www.wikidoc.org/index.php/CHD1L | |
677a3a6f0997632feab6032ec619975c57b1c6ef | wikidoc | CHEK1 | CHEK1
Checkpoint kinase 1, commonly referred to as Chk1, is a serine/threonine-specific protein kinase that, in humans, is encoded by the CHEK1 gene. Chk1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response. Activation of Chk1 results in the initiation of cell cycle checkpoints, cell cycle arre... | CHEK1
Checkpoint kinase 1, commonly referred to as Chk1, is a serine/threonine-specific protein kinase that, in humans, is encoded by the CHEK1 gene.[1][2] Chk1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response.[3] Activation of Chk1 results in the initiation of cell cycle checkpoints, cell ... | https://www.wikidoc.org/index.php/CHEK1 | |
b82c2fbde7dfc525887c8cf5a127ff0ad882c8f4 | wikidoc | CHEK2 | CHEK2
CHEK2 (Checkpoint kinase 2) is a tumor suppressor gene that encodes the protein CHK2, a serine-threonine kinase. CHK2 is involved in DNA repair, cell cycle arrest or apoptosis in response to DNA damage. Mutations to the CHEK2 gene have been linked to a wide range of cancers.
# Gene location
The CHEK2 gene is loc... | CHEK2
CHEK2 (Checkpoint kinase 2) is a tumor suppressor gene that encodes the protein CHK2, a serine-threonine kinase. CHK2 is involved in DNA repair, cell cycle arrest or apoptosis in response to DNA damage. Mutations to the CHEK2 gene have been linked to a wide range of cancers.[1]
# Gene location
The CHEK2 gene is... | https://www.wikidoc.org/index.php/CHEK2 | |
907f2abee36de44947728cff6934e96746b47249 | wikidoc | CHHIP | CHHIP
# Overview
CHHIP stands for Conventional or Hypofractionated High Dose Intensity Modulated Radiotherapy for Prostate Cancer, a treatment protocol currently undergoing clinical trials for the treatment of prostate cancer using external beam radiotherapy.
# Protocol Details
The main arm of the protocol prescribes... | CHHIP
# Overview
CHHIP stands for Conventional or Hypofractionated High Dose Intensity Modulated Radiotherapy for Prostate Cancer, a treatment protocol currently undergoing clinical trials for the treatment of prostate cancer using external beam radiotherapy.
# Protocol Details
The main arm of the protocol prescribes... | https://www.wikidoc.org/index.php/CHHIP | |
37fd6c9a3f48fa05ab8cad7b38a08422d4746ba0 | wikidoc | CHODL | CHODL
Chondrolectin is a protein that in humans is encoded by the CHODL gene. Mouse chondrolectin is encoded by Chodl.
# Structure
Chondrolectin is a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved ... | CHODL
Chondrolectin is a protein that in humans is encoded by the CHODL gene.[1][2] Mouse chondrolectin is encoded by Chodl.[3]
# Structure
Chondrolectin is a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion.[1][3] In other proteins, this dom... | https://www.wikidoc.org/index.php/CHODL | |
a6962a35040a6fc106e2490c0d782c99e89276ec | wikidoc | CHRND | CHRND
Acetylcholine receptor subunit delta is a protein that in humans is encoded by the CHRND gene.
# Function
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation ... | CHRND
Acetylcholine receptor subunit delta is a protein that in humans is encoded by the CHRND gene.[1]
# Function
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformat... | https://www.wikidoc.org/index.php/CHRND | |
65b70e855b1b91bea9b6d62fbc34359284590783 | wikidoc | CHRNE | CHRNE
Acetylcholine receptor subunit epsilon is a protein that in humans is encoded by the CHRNE gene.
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The ac... | CHRNE
Acetylcholine receptor subunit epsilon is a protein that in humans is encoded by the CHRNE gene.[1][2]
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit.... | https://www.wikidoc.org/index.php/CHRNE | |
aa51a0360fb3c11ab8ab076ba06b76567de8ac20 | wikidoc | CIITA | CIITA
CIITA is a human gene which encodes a protein called the class II, major histocompatibility complex, transactivator. Mutations in this gene are responsible for the bare lymphocyte syndrome in which the immune system is severely compromised and cannot effectively fight infection. Chromosomal rearrangement of CIIT... | CIITA
CIITA is a human gene which encodes a protein called the class II, major histocompatibility complex, transactivator.[1] Mutations in this gene are responsible for the bare lymphocyte syndrome in which the immune system is severely compromised and cannot effectively fight infection.[1] Chromosomal rearrangement ... | https://www.wikidoc.org/index.php/CIITA | |
34781966ed12c1b782b7178838570578543042a3 | wikidoc | CKAP2 | CKAP2
Cytoskeleton-associated protein 2 is a protein that in humans is encoded by the CKAP2 gene.
Human CKAP2 gene, the cDNA of which is known as LB1, is a cytoskeleton-associated protein involved in mitotic progression. Its high transcriptional activity has been observed in the testes, thymus, and diffuse B-cell lymph... | CKAP2
Cytoskeleton-associated protein 2 is a protein that in humans is encoded by the CKAP2 gene.[1][2]
Human CKAP2 gene, the cDNA of which is known as LB1, is a cytoskeleton-associated protein involved in mitotic progression. Its high transcriptional activity has been observed in the testes, thymus, and diffuse B-cel... | https://www.wikidoc.org/index.php/CKAP2 | |
38350d0efb410661d1b403cfe0fbdc69b2962d18 | wikidoc | CKAP4 | CKAP4
Cytoskeleton-associated protein 4 is a protein that in humans is encoded by the CKAP4 gene.
CKAP4 also historically known as CLIMP-63 (cytoskeleton-linking membrane protein 63), or just p63 (during the 90’s) is an abundant type II transmembrane protein residing predominantly in the endoplasmic reticulum (ER) of e... | CKAP4
Cytoskeleton-associated protein 4 is a protein that in humans is encoded by the CKAP4 gene.[1][2]
CKAP4 also historically known as CLIMP-63 (cytoskeleton-linking membrane protein 63), or just p63 (during the 90’s) is an abundant type II transmembrane protein residing predominantly in the endoplasmic reticulum (E... | https://www.wikidoc.org/index.php/CKAP4 | |
b33e262e6ffccdf589e093879482a8977fa766b5 | wikidoc | CKMT2 | CKMT2
Creatine kinase S-type, mitochondrial is an enzyme that in humans is encoded by the CKMT2 gene.
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. The "energy-rich" gamma-phosphate group of ATP that is generated by ox... | CKMT2
Creatine kinase S-type, mitochondrial is an enzyme that in humans is encoded by the CKMT2 gene.[1][2]
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. The "energy-rich" gamma-phosphate group of ATP that is generate... | https://www.wikidoc.org/index.php/CKMT2 | |
e37efe2b8c04cb82935841add9f81cc42b5735aa | wikidoc | CKS1B | CKS1B
Cyclin-dependent kinases regulatory subunit 1 is a protein that in humans is encoded by the CKS1B gene.
# Function
The CKS1B protein binds to the catalytic subunit of the cyclin-dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through... | CKS1B
Cyclin-dependent kinases regulatory subunit 1 is a protein that in humans is encoded by the CKS1B gene.[1][2]
# Function
The CKS1B protein binds to the catalytic subunit of the cyclin-dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns ... | https://www.wikidoc.org/index.php/CKS1B | |
f40ed29cdc161cbe70a249a6ed6b96470c225236 | wikidoc | CLCF1 | CLCF1
Cardiotrophin-like cytokine factor 1 (CLCF1), also known as Novel Neurotrophin-1 (NNT-1) or B cell-stimulating factor-3 (BSF-3), is a protein that in humans is encoded by the CLCF1 gene.
# Function
CLCF1 induces tyrosine phosphorylation of the IL-6 receptor common subunit glycoprotein 130 (gp130), leukemia inhib... | CLCF1
Cardiotrophin-like cytokine factor 1 (CLCF1), also known as Novel Neurotrophin-1 (NNT-1) or B cell-stimulating factor-3 (BSF-3), is a protein that in humans is encoded by the CLCF1 gene.[1]
# Function
CLCF1 induces tyrosine phosphorylation of the IL-6 receptor common subunit glycoprotein 130 (gp130), leukemia i... | https://www.wikidoc.org/index.php/CLCF1 | |
5bb2c583b13613518ab1ae55df9792d061c8439e | wikidoc | CLCN1 | CLCN1
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Muta... | CLCN1
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mut... | https://www.wikidoc.org/index.php/CLCN1 | |
1df4c61cd5456e166238f1925da7f6a6c7c708f8 | wikidoc | CLCN4 | CLCN4
H(+)/Cl(-) exchange transporter 4 is a protein that in humans is encoded by the CLCN4 gene.
# Function
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Ch... | CLCN4
H(+)/Cl(-) exchange transporter 4 is a protein that in humans is encoded by the CLCN4 gene.[1][2]
# Function
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homol... | https://www.wikidoc.org/index.php/CLCN4 | |
438b8bd675fea6567ce2317e2262675a1f6817b6 | wikidoc | CLDN2 | CLDN2
Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. It belongs to the group of claudins.
Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions (Sakaguchi et al., 2002).
# Function
... | CLDN2
Claudin-2 is a protein that in humans is encoded by the CLDN2 gene.[1][2] It belongs to the group of claudins.
Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions (Sakaguchi et al., 2002).[suppl... | https://www.wikidoc.org/index.php/CLDN2 | |
65bb5a71facb256755bbf428c6a27de51d2c3b3f | wikidoc | CLIC4 | CLIC4
Chloride intracellular channel 4, also known as CLIC4, is a eukaryotic gene.
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume.... | CLIC4
Chloride intracellular channel 4, also known as CLIC4, is a eukaryotic gene.[1]
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell vol... | https://www.wikidoc.org/index.php/CLIC4 | |
ec13dee9b56dfd7fec995c2741de53473b7fd279 | wikidoc | CLIC5 | CLIC5
Chloride intracellular channel protein 5 is a protein that in humans is encoded by the CLIC5 gene.
# Expression and localization
CLIC5 exists in two alternative splice variants, a smaller CLIC5A and larger CLIC5B protein.
CLIC5A is expressed chiefly in the renal glomerulus, specifically in podocytes. Within the ... | CLIC5
Chloride intracellular channel protein 5 is a protein that in humans is encoded by the CLIC5 gene.[1][2]
# Expression and localization
CLIC5 exists in two alternative splice variants, a smaller CLIC5A and larger CLIC5B protein.
CLIC5A is expressed chiefly in the renal glomerulus, specifically in podocytes. With... | https://www.wikidoc.org/index.php/CLIC5 | |
20b098d8b0b2c9b5dcaecf2a268a6cefad31d7b9 | wikidoc | CLOCK | CLOCK
Clock (Circadian Locomotor Output Cycles Kaput) is a gene encoding a basic helix-loop-helix-PAS transcription factor (CLOCK) that is believed to affect both the persistence and period of circadian rhythms.
Research shows that the CLOCK gene plays a major role as an activator of downstream elements in the pathway ... | CLOCK
Clock (Circadian Locomotor Output Cycles Kaput) is a gene encoding a basic helix-loop-helix-PAS transcription factor (CLOCK) that is believed to affect both the persistence and period of circadian rhythms.
Research shows that the CLOCK gene plays a major role as an activator of downstream elements in the pathway... | https://www.wikidoc.org/index.php/CLOCK | |
68bfa9d009d6b1e49074840e4640bde190ca41ff | wikidoc | CNDP1 | CNDP1
Beta-Ala-His dipeptidase is an enzyme that in humans is encoded by the CNDP1 gene.
This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG... | CNDP1
Beta-Ala-His dipeptidase is an enzyme that in humans is encoded by the CNDP1 gene.[1][2]
This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleoti... | https://www.wikidoc.org/index.php/CNDP1 | |
4d5634666e3c47d5ade88ccd8663d3b3362476ad | wikidoc | COPII | COPII
COPII is a coatomer, a type of vesicle coat protein that transports proteins from the rough endoplasmic reticulum to the Golgi apparatus. This process is termed anterograde transport, in contrast to the retrograde transport associated with the COPI protein. The name "COPII" refers to the specific coat protein com... | COPII
COPII is a coatomer, a type of vesicle coat protein that transports proteins from the rough endoplasmic reticulum to the Golgi apparatus.[2][3] This process is termed anterograde transport, in contrast to the retrograde transport associated with the COPI protein. The name "COPII" refers to the specific coat prot... | https://www.wikidoc.org/index.php/COPII | |
8f063eadef27d497cd8a4db20284dde0a2fe85f5 | wikidoc | CORIN | CORIN
Corin, also called atrial natriuretic peptide-converting enzyme, is a protein that in humans is encoded by the CORIN gene.
# Protein
Human corin, a polypeptide of 1042 amino acids, consists of an N-terminal cytoplasmic domain, a transmembrane domain and an extracellular region with two frizzled-like domains, eig... | CORIN
Corin, also called atrial natriuretic peptide-converting enzyme, is a protein that in humans is encoded by the CORIN gene.[1][2]
# Protein
Human corin, a polypeptide of 1042 amino acids, consists of an N-terminal cytoplasmic domain, a transmembrane domain and an extracellular region with two frizzled-like domai... | https://www.wikidoc.org/index.php/CORIN | |
b83137a2fb08c1123f2b326e168def112a8228a6 | wikidoc | CORO6 | CORO6
Coronin-6 also known as coronin-like protein E (Clipin-E) is a protein that in humans is encoded by the CORO6 gene.
Coronin-6 is belongs to coronin family which is an actin binding protein. Human CORO6 gene is located on chromosome 17 on the cytogenetic band 17 p11.2. Gene CORO6 is well conserved across domain of... | CORO6
Coronin-6 also known as coronin-like protein E (Clipin-E) is a protein that in humans is encoded by the CORO6 gene.
Coronin-6 is belongs to coronin family which is an actin binding protein.[1][2] Human CORO6 gene is located on chromosome 17 on the cytogenetic band 17 p11.2.[3] Gene CORO6 is well conserved across... | https://www.wikidoc.org/index.php/CORO6 | |
186f75418c40747f95b48526be9836d1c2cdfc1e | wikidoc | COTL1 | COTL1
Coactosin-like protein (COTL1 or CLP) is a protein that in humans is encoded by the COTL1 gene.
# Function
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with and thereby stabilizes 5-lipoxygenase (ALOX5). Althoug... | COTL1
Coactosin-like protein (COTL1 or CLP) is a protein that in humans is encoded by the COTL1 gene.[1][2][3][4]
# Function
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with and thereby stabilizes 5-lipoxygenase (AL... | https://www.wikidoc.org/index.php/COTL1 | |
0991f11e93a0cf2f241332da29eea7ef90241c15 | wikidoc | PTGS1 | PTGS1
Cyclooxygenase 1 (COX-1), also known as prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1, is an enzyme that in humans is encoded by the PTGS1 gene. In humans it is one of two cyclooxygenases.
# History
Cyclooxygenase (COX) is the central enzyme in the biosyntheti... | PTGS1
Cyclooxygenase 1 (COX-1), also known as prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1, is an enzyme that in humans is encoded by the PTGS1 gene.[1][2] In humans it is one of two cyclooxygenases.
# History
Cyclooxygenase (COX) is the central enzyme in the bios... | https://www.wikidoc.org/index.php/COX-1 | |
2069c0b8a5752748f6a9b34254247005c2350389 | wikidoc | COX10 | COX10
Protoheme IX farnesyltransferase, mitochondrial is an enzyme that in humans is encoded by the COX10 gene. Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisti... | COX10
Protoheme IX farnesyltransferase, mitochondrial is an enzyme that in humans is encoded by the COX10 gene.[1][2] Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex c... | https://www.wikidoc.org/index.php/COX10 | |
2cf9342d5df831d5cc2f8b8b608ea811ce2e664b | wikidoc | COX14 | COX14
Cytochrome c oxidase assembly factor COX14 is a protein that in humans is encoded by the COX14 gene. This gene encodes a small single-pass transmembrane protein that localizes to mitochondria. This protein may play a role in coordinating the early steps of cytochrome c oxidase (COX; also known as complex IV) subu... | COX14
Cytochrome c oxidase assembly factor COX14 is a protein that in humans is encoded by the COX14 gene. This gene encodes a small single-pass transmembrane protein that localizes to mitochondria. This protein may play a role in coordinating the early steps of cytochrome c oxidase (COX; also known as complex IV) sub... | https://www.wikidoc.org/index.php/COX14 | |
c1542f68f62cfbcd2647d864719ae1618ab5480a | wikidoc | COX15 | COX15
Cytochrome c oxidase assembly protein COX15 homolog (COX15), also known as heme A synthase, is a protein that in humans is encoded by the COX15 gene. This protein localizes to the inner mitochondrial membrane and involved in heme A biosynthesis. COX15 is also part of a three-component mono-oxygenase (ferredoxin, ... | COX15
Cytochrome c oxidase assembly protein COX15 homolog (COX15), also known as heme A synthase, is a protein that in humans is encoded by the COX15 gene.[1][2] This protein localizes to the inner mitochondrial membrane and involved in heme A biosynthesis.[3] COX15 is also part of a three-component mono-oxygenase (fe... | https://www.wikidoc.org/index.php/COX15 | |
4261710dcd143c1f2d58fcde4de0db8213d1df5c | wikidoc | COX20 | COX20
Cytochrome c oxidase assembly factor COX20 is a protein that in humans is encoded by the COX20 gene.This gene encodes a protein that plays a role in the assembly of cytochrome c oxidase, an important component of the respiratory pathway. Mutations in this gene can cause mitochondrial complex IV deficiency. There ... | COX20
Cytochrome c oxidase assembly factor COX20 is a protein that in humans is encoded by the COX20 gene.This gene encodes a protein that plays a role in the assembly of cytochrome c oxidase, an important component of the respiratory pathway. Mutations in this gene can cause mitochondrial complex IV deficiency. There... | https://www.wikidoc.org/index.php/COX20 | |
b2000a5ea43375c6388d461554f18ba143be366c | wikidoc | COX5A | COX5A
Cytochrome c oxidase subunit 5a is a protein that in humans is encoded by the COX5A gene. Cytochrome c oxidase 5A is a subunit of the cytochrome c oxidase complex, also known as Complex IV, the last enzyme in the mitochondrial electron transport chain.
# Structure
The COX5A gene, located on the q arm of chromoso... | COX5A
Cytochrome c oxidase subunit 5a is a protein that in humans is encoded by the COX5A gene. Cytochrome c oxidase 5A is a subunit of the cytochrome c oxidase complex, also known as Complex IV, the last enzyme in the mitochondrial electron transport chain.[1]
# Structure
The COX5A gene, located on the q arm of chro... | https://www.wikidoc.org/index.php/COX5A | |
424db27a47bfe062fdbc08919e9a3f46ac5c7665 | wikidoc | COX5B | COX5B
Cytochrome c oxidase subunit 5B, mitochondrial is an enzyme in humans that is a subunit of the cytochrome c oxidase complex, also known as Complex IV, the last enzyme in the mitochondrial electron transport chain. In humans, cytochrome c oxidase subunit 5B is encoded by the COX5B gene.
# Structure
The enzyme wei... | COX5B
Cytochrome c oxidase subunit 5B, mitochondrial is an enzyme in humans that is a subunit of the cytochrome c oxidase complex, also known as Complex IV, the last enzyme in the mitochondrial electron transport chain.[2] In humans, cytochrome c oxidase subunit 5B is encoded by the COX5B gene.
# Structure
The enzyme... | https://www.wikidoc.org/index.php/COX5B | |
8e4412bc298d01bd622d84a25b7deb4c9beac357 | wikidoc | COX7B | COX7B
Cytochrome c oxidase subunit 7B, mitochondrial (COX7B) is an enzyme that in humans is encoded by the COX7B gene. COX7B is a nuclear-encoded subunit of cytochrome c oxidase (COX). Cytochrome c oxidase (complex IV) is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecul... | COX7B
Cytochrome c oxidase subunit 7B, mitochondrial (COX7B) is an enzyme that in humans is encoded by the COX7B gene.[1] COX7B is a nuclear-encoded subunit of cytochrome c oxidase (COX). Cytochrome c oxidase (complex IV) is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to mol... | https://www.wikidoc.org/index.php/COX7B | |
37f71148cef8b3fc93aea9db801ae786e6cc2a3a | wikidoc | COX8A | COX8A
Cytochrome c oxidase subunit 8A (COX8A) is a protein that in humans is encoded by the COX8A gene. Cytochrome c oxidase 8A is a subunit of the cytochrome c oxidase complex, also known as Complex IV. Mutations in the COX8A gene have been associated with complex IV deficiency with Leigh syndrome and epilepsy.
# Str... | COX8A
Cytochrome c oxidase subunit 8A (COX8A) is a protein that in humans is encoded by the COX8A gene.[1] Cytochrome c oxidase 8A is a subunit of the cytochrome c oxidase complex, also known as Complex IV. Mutations in the COX8A gene have been associated with complex IV deficiency with Leigh syndrome and epilepsy.[2]... | https://www.wikidoc.org/index.php/COX8A | |
c3c1f2eea9e45e19906d2000e9a0f390f276c9ca | wikidoc | CRADD | CRADD
Death domain-containing protein CRADD is a protein that in humans is encoded by the CRADD gene.
# Function
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase ... | CRADD
Death domain-containing protein CRADD is a protein that in humans is encoded by the CRADD gene.[1][2][3]
# Function
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits... | https://www.wikidoc.org/index.php/CRADD | |
142ed5b25685a93638c694f1de9f3c168b88e989 | wikidoc | CRIM1 | CRIM1
Cysteine-rich motor neuron 1 protein is a protein that in humans is encoded by the CRIM1 gene.
# Function
Motor neurons are among the earliest neurons to appear after the commencement of cell patterning and the beginning of cell differentiation. Differentiation occurs in a ventral-to-dorsal gradient and is media... | CRIM1
Cysteine-rich motor neuron 1 protein is a protein that in humans is encoded by the CRIM1 gene.[1][2]
# Function
Motor neurons are among the earliest neurons to appear after the commencement of cell patterning and the beginning of cell differentiation. Differentiation occurs in a ventral-to-dorsal gradient and i... | https://www.wikidoc.org/index.php/CRIM1 | |
f13534485e234196a101afa2f5e6533c52d06d27 | wikidoc | CRLF1 | CRLF1
Cytokine receptor-like factor 1 is a protein that in humans is encoded by the CRLF1 gene.
# Function
This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors... | CRLF1
Cytokine receptor-like factor 1 is a protein that in humans is encoded by the CRLF1 gene.[1][2]
# Function
This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor re... | https://www.wikidoc.org/index.php/CRLF1 | |
8ab6bbedf14f1fc88a161b6bd8a8fc428395f9e5 | wikidoc | CRMP1 | CRMP1
Collapsin response mediator protein 1, encoded by the CRMP1 gene, is a human protein of the CRMP family.
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implic... | CRMP1
Collapsin response mediator protein 1, encoded by the CRMP1 gene, is a human protein of the CRMP family.[1]
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway im... | https://www.wikidoc.org/index.php/CRMP1 | |
b6c89c1e48693c9ba61a5338c4a98e2f7599f91d | wikidoc | CRSP3 | CRSP3
Mediator of RNA polymerase II transcription subunit 23 is an enzyme that in humans is encoded by the MED23 gene.
# Function
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direc... | CRSP3
Mediator of RNA polymerase II transcription subunit 23 is an enzyme that in humans is encoded by the MED23 gene.[1][2]
# Function
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators t... | https://www.wikidoc.org/index.php/CRSP3 | |
98d2af4b25fabc406a48aca45daefc6787012a73 | wikidoc | CRTC1 | CRTC1
CREB-regulated transcription coactivator 1 (CRTC1), previously referred to as TORC1 (Transducer Of Regulated CREB activity 1), is a protein that in humans is encoded by the CRTC1 gene. It is expressed in a limited number of tissues that include fetal brain and liver and adult heart, skeletal muscles, liver and s... | CRTC1
CREB-regulated transcription coactivator 1 (CRTC1), previously referred to as TORC1 (Transducer Of Regulated CREB activity 1), is a protein that in humans is encoded by the CRTC1 gene.[1][2][3][4] It is expressed in a limited number of tissues that include fetal brain and liver and adult heart, skeletal muscles... | https://www.wikidoc.org/index.php/CRTC1 | |
875f1f37b491ec18271814c9da92c98aa1f8ebc4 | wikidoc | CRYAA | CRYAA
Alpha-crystallin A chain is a protein that in humans is encoded by the CRYAA gene.
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since le... | CRYAA
Alpha-crystallin A chain is a protein that in humans is encoded by the CRYAA gene.[1]
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Sinc... | https://www.wikidoc.org/index.php/CRYAA | |
ee512614663ed7c998bc1bf1e86518ff4ef46bab | wikidoc | CRYGC | CRYGC
Crystallin, gamma C, also known as CRYGC, is a protein which in humans is encoded by the CRYGC gene.
# Function
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refracti... | CRYGC
Crystallin, gamma C, also known as CRYGC, is a protein which in humans is encoded by the CRYGC gene.[1][2]
# Function
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and r... | https://www.wikidoc.org/index.php/CRYGC | |
adadb027d12ddee1c358670db120bd70801a3ef0 | wikidoc | CRYGS | CRYGS
Gamma-crystallin S is a protein that in humans is encoded by the CRYGS gene.
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens cen... | CRYGS
Gamma-crystallin S is a protein that in humans is encoded by the CRYGS gene.[1]
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens... | https://www.wikidoc.org/index.php/CRYGS |
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