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wikidoc
PSMC6
PSMC6 26S protease regulatory subunit S10B, also known as 26S proteasome AAA-ATPase subunit Rpt4,is an enzyme that in humans is encoded by the PSMC6 gene. This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3, Rpt4 (this ...
PSMC6 26S protease regulatory subunit S10B, also known as 26S proteasome AAA-ATPase subunit Rpt4,is an enzyme that in humans is encoded by the PSMC6 gene.[1][2][3] This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex[4] Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3...
https://www.wikidoc.org/index.php/PSMC6
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wikidoc
PSMD1
PSMD1 26S proteasome non-ATPase regulatory subunit 1, also as known as 26S Proteasome Regulatory Subunit Rpn2 (systematic nomenclature), is a protein that in humans is encoded by the PSMD1 gene. This protein is one of the 19 essential subunits that contributes to the complete assembly of 19S proteasome complex. # Str...
PSMD1 26S proteasome non-ATPase regulatory subunit 1, also as known as 26S Proteasome Regulatory Subunit Rpn2 (systematic nomenclature), is a protein that in humans is encoded by the PSMD1 gene.[1][2] This protein is one of the 19 essential subunits that contributes to the complete assembly of 19S proteasome complex....
https://www.wikidoc.org/index.php/PSMD1
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wikidoc
PSMD2
PSMD2 26S proteasome non-ATPase regulatory subunit 2, also as known as 26S Proteasome Regulatory Subunit Rpn1 (systematic nomenclature), is an enzyme that in humans is encoded by the PSMD2 gene. # Structure ## Gene expression The gene PSMD2 encodes a non-ATPase subunit of the 19S regulator base, which is responsible ...
PSMD2 26S proteasome non-ATPase regulatory subunit 2, also as known as 26S Proteasome Regulatory Subunit Rpn1 (systematic nomenclature), is an enzyme that in humans is encoded by the PSMD2 gene.[1][2] # Structure ## Gene expression The gene PSMD2 encodes a non-ATPase subunit of the 19S regulator base, which is respo...
https://www.wikidoc.org/index.php/PSMD2
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wikidoc
PSMD3
PSMD3 26S proteasome non-ATPase regulatory subunit 3 is an enzyme that in humans is encoded by the PSMD3 gene. # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-iden...
PSMD3 26S proteasome non-ATPase regulatory subunit 3 is an enzyme that in humans is encoded by the PSMD3 gene.[1][2] # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 n...
https://www.wikidoc.org/index.php/PSMD3
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wikidoc
PSMD4
PSMD4 26S proteasome non-ATPase regulatory subunit 4, also as known as 26S Proteasome Regulatory Subunit Rpn10 (systematic nomenclature), is an enzyme that in humans is encoded by the PSMD4 gene. This protein is one of the 19 essential subunits that contributes to the complete assembly of 19S proteasome complex. # Gen...
PSMD4 26S proteasome non-ATPase regulatory subunit 4, also as known as 26S Proteasome Regulatory Subunit Rpn10 (systematic nomenclature), is an enzyme that in humans is encoded by the PSMD4 gene.[1][2] This protein is one of the 19 essential subunits that contributes to the complete assembly of 19S proteasome complex....
https://www.wikidoc.org/index.php/PSMD4
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wikidoc
PSMD5
PSMD5 26S proteasome non-ATPase regulatory subunit 5 is an enzyme that in humans is encoded by the PSMD5 gene. # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-iden...
PSMD5 26S proteasome non-ATPase regulatory subunit 5 is an enzyme that in humans is encoded by the PSMD5 gene.[1] # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-...
https://www.wikidoc.org/index.php/PSMD5
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wikidoc
PSMD6
PSMD6 26S proteasome non-ATPase regulatory subunit 6 is an enzyme that in humans is encoded by the PSMD6 gene. # Clinical significance The Proteasome and its subunits are of clinical significance for at least two reasons: (1) a compromised complex assembly or a dysfunctional proteasome can be associated with the under...
PSMD6 26S proteasome non-ATPase regulatory subunit 6 is an enzyme that in humans is encoded by the PSMD6 gene.[1][2] # Clinical significance The Proteasome and its subunits are of clinical significance for at least two reasons: (1) a compromised complex assembly or a dysfunctional proteasome can be associated with th...
https://www.wikidoc.org/index.php/PSMD6
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wikidoc
PSMD7
PSMD7 26S proteasome non-ATPase regulatory subunit 7, also known as 26S proteasome non-ATPase subunit Rpn8, is an enzyme that in humans is encoded by the PSMD7 gene. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S...
PSMD7 26S proteasome non-ATPase regulatory subunit 7, also known as 26S proteasome non-ATPase subunit Rpn8, is an enzyme that in humans is encoded by the PSMD7 gene.[1][2] The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. ...
https://www.wikidoc.org/index.php/PSMD7
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wikidoc
PSMD8
PSMD8 26S proteasome non-ATPase regulatory subunit 8 is an enzyme that in humans is encoded by the PSMD8 gene. # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-iden...
PSMD8 26S proteasome non-ATPase regulatory subunit 8 is an enzyme that in humans is encoded by the PSMD8 gene.[1][2] # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 n...
https://www.wikidoc.org/index.php/PSMD8
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wikidoc
PSMD9
PSMD9 26S proteasome non-ATPase regulatory subunit 9 is an enzyme that in humans is encoded by the PSMD9 gene. # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-iden...
PSMD9 26S proteasome non-ATPase regulatory subunit 9 is an enzyme that in humans is encoded by the PSMD9 gene.[1][2] # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 n...
https://www.wikidoc.org/index.php/PSMD9
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wikidoc
PTBP1
PTBP1 Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These protei...
PTBP1 Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene.[1][2][3] This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). Th...
https://www.wikidoc.org/index.php/PTBP1
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wikidoc
PTCH1
PTCH1 Protein patched homolog 1 is a protein that is the member of the patched family and in humans is encoded by the PTCH1 gene. # Function PTCH1 is a member of the patched gene family and is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis....
PTCH1 Protein patched homolog 1 is a protein that is the member of the patched family and in humans is encoded by the PTCH1 gene.[1][2] # Function PTCH1 is a member of the patched gene family and is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorig...
https://www.wikidoc.org/index.php/PTCH1
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wikidoc
PTCH2
PTCH2 Patched 2 is a protein that in humans is encoded by the PTCH2 gene. # Function This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. # Clinical significance Alterations in this gene have been associated wi...
PTCH2 Patched 2 is a protein that in humans is encoded by the PTCH2 gene.[1] # Function This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway.[1] # Clinical significance Alterations in this gene have been associ...
https://www.wikidoc.org/index.php/PTCH2
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wikidoc
PTK2B
PTK2B Protein tyrosine kinase 2 beta is an enzyme that in humans is encoded by the PTK2B gene. # Function This gene encodes a cytoplasmic protein tyrosine kinase that is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an impor...
PTK2B Protein tyrosine kinase 2 beta is an enzyme that in humans is encoded by the PTK2B gene.[1][2] # Function This gene encodes a cytoplasmic protein tyrosine kinase that is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent a...
https://www.wikidoc.org/index.php/PTK2B
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wikidoc
PTPN1
PTPN1 Tyrosine-protein phosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme that is the founding member of the protein tyrosine phosphatase (PTP) family. In humans it is encoded by the PTPN1 gene. PTP1B is a negative regulator of the insulin signaling pathway and is conside...
PTPN1 Tyrosine-protein phosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme that is the founding member of the protein tyrosine phosphatase (PTP) family. In humans it is encoded by the PTPN1 gene.[1] PTP1B is a negative regulator of the insulin signaling pathway and is con...
https://www.wikidoc.org/index.php/PTPN1
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wikidoc
PTPN5
PTPN5 Protein tyrosine phosphatase non-receptor type 5 is an enzyme that in humans is encoded by the PTPN5 gene. Protein tyrosine phosphatase (PTP), non-receptor type 5, also known as STEP (STriatal-Enriched protein tyrosine Phosphatase), was the first brain-specific PTP discovered. The human STEP locus maps to chromos...
PTPN5 Protein tyrosine phosphatase non-receptor type 5 is an enzyme that in humans is encoded by the PTPN5 gene.[1][2] Protein tyrosine phosphatase (PTP), non-receptor type 5, also known as STEP (STriatal-Enriched protein tyrosine Phosphatase), was the first brain-specific PTP discovered.[1] The human STEP locus maps ...
https://www.wikidoc.org/index.php/PTPN5
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wikidoc
PTPN6
PTPN6 Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), is an enzyme that in humans is encoded by the PTPN6 gene. # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be s...
PTPN6 Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), is an enzyme that in humans is encoded by the PTPN6 gene.[1] # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to ...
https://www.wikidoc.org/index.php/PTPN6
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wikidoc
PTPRB
PTPRB Receptor-type tyrosine-protein phosphatase beta or VE-PTP is an enzyme specifically expressed in endothelial cells that in humans is encoded by the PTPRB gene. # Function VE-PTP is a member of the classical protein tyrosine phosphatase (PTP) family. The deletion of the gene in mouse models was shown to be embry...
PTPRB Receptor-type tyrosine-protein phosphatase beta or VE-PTP is an enzyme specifically expressed in endothelial cells that in humans is encoded by the PTPRB gene.[1][2] # Function VE-PTP is a member of the classical protein tyrosine phosphatase (PTP) family. The deletion of the gene in mouse models was shown to b...
https://www.wikidoc.org/index.php/PTPRB
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wikidoc
PTPRC
PTPRC Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene. PTPRC is also known as CD45 antigen (CD stands for cluster of differentiation), which was originally called leukocyte common antigen (LCA). # Function The protein encoded by this gene i...
PTPRC Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene.[1] PTPRC is also known as CD45 antigen (CD stands for cluster of differentiation), which was originally called leukocyte common antigen (LCA).[2] # Function The protein encoded by this...
https://www.wikidoc.org/index.php/PTPRC
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wikidoc
PTPRD
PTPRD Receptor-type tyrosine-protein phosphatase delta is an enzyme that in humans is encoded by the PTPRD gene. # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cel...
PTPRD Receptor-type tyrosine-protein phosphatase delta is an enzyme that in humans is encoded by the PTPRD gene.[1][2][3] # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes inc...
https://www.wikidoc.org/index.php/PTPRD
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wikidoc
PTPRK
PTPRK Receptor-type tyrosine-protein phosphatase kappa is an enzyme that in humans is encoded by the PTPRK gene. PTPRK is also known as PTPkappa and PTPκ. # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Protein tyrosine phosphatases are protein enzymes that rem...
PTPRK Receptor-type tyrosine-protein phosphatase kappa is an enzyme that in humans is encoded by the PTPRK gene.[1][2][3] PTPRK is also known as PTPkappa and PTPκ. # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Protein tyrosine phosphatases are protein enzyme...
https://www.wikidoc.org/index.php/PTPRK
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wikidoc
PTPRM
PTPRM Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene. # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Protein tyrosine phosphatases are protein enzymes that remove phosphate moieties from tyrosine residues...
PTPRM Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene.[1][2][3] # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Protein tyrosine phosphatases are protein enzymes that remove phosphate moieties from tyrosin...
https://www.wikidoc.org/index.php/PTPRM
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wikidoc
PTPRS
PTPRS Receptor-type tyrosine-protein phosphatase S, also known as R-PTP-S, R-PTP-sigma, or PTPσ, is an enzyme that in humans is encoded by the PTPRS gene. # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a v...
PTPRS Receptor-type tyrosine-protein phosphatase S, also known as R-PTP-S, R-PTP-sigma, or PTPσ, is an enzyme that in humans is encoded by the PTPRS gene.[1][2][3] # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that re...
https://www.wikidoc.org/index.php/PTPRS
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wikidoc
PTPRT
PTPRT Receptor-type tyrosine-protein phosphatase T is an enzyme that in humans is encoded by the PTPRT gene. PTPRT is also known as PTPrho, PTPρ and human accelerated region 9. The human accelerated regions are 49 regions of the human genome that are conserved among vertebrates, but in humans show significant distinct...
PTPRT Receptor-type tyrosine-protein phosphatase T is an enzyme that in humans is encoded by the PTPRT gene.[1][2][3] PTPRT is also known as PTPrho, PTPρ and human accelerated region 9. The human accelerated regions are 49 regions of the human genome that are conserved among vertebrates, but in humans show significan...
https://www.wikidoc.org/index.php/PTPRT
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wikidoc
PTPRU
PTPRU Receptor-type tyrosine-protein phosphatase PCP-2 (also known as PTP-pi, PTP lambda, hPTP-J, PTPRO and PTP psi), is an enzyme that in humans is encoded by the PTPRU gene. # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecu...
PTPRU Receptor-type tyrosine-protein phosphatase PCP-2 (also known as PTP-pi, PTP lambda, hPTP-J, PTPRO and PTP psi), is an enzyme that in humans is encoded by the PTPRU gene.[1][2][3] # Function The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signal...
https://www.wikidoc.org/index.php/PTPRU
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wikidoc
PTTG1
PTTG1 Securin is a protein that in humans is encoded by the PTTG1 gene. # Function The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the AP...
PTTG1 Securin is a protein that in humans is encoded by the PTTG1 gene.[1][2][3] # Function The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation...
https://www.wikidoc.org/index.php/PTTG1
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wikidoc
PUS7L
PUS7L Pseudouridylate synthase 7 homolog-like protein is an enzyme that in humans is encoded by the PUS7L gene. # Model organisms Model organisms have been used in the study of PUS7L function. A conditional knockout mouse line, called Pus7ltm2a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consor...
PUS7L Pseudouridylate synthase 7 homolog-like protein is an enzyme that in humans is encoded by the PUS7L gene.[1][2] # Model organisms Model organisms have been used in the study of PUS7L function. A conditional knockout mouse line, called Pus7ltm2a(KOMP)Wtsi[7][8] was generated as part of the International Knockout...
https://www.wikidoc.org/index.php/PUS7L
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wikidoc
PYCR2
PYCR2 Pyrroline-5-carboxylate reductase family, member 2 is a protein that in humans is encoded by the PYCR2 gene. # Function This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in pr...
PYCR2 Pyrroline-5-carboxylate reductase family, member 2 is a protein that in humans is encoded by the PYCR2 gene.[1] # Function This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step i...
https://www.wikidoc.org/index.php/PYCR2
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wikidoc
Taxus
Taxus Taxus is a genus of yews, small coniferous trees or shrubs in the yew family Taxaceae. They are relatively slow growing and can be very long-lived, and reach heights of 1-40 m, with trunk diameters of up to 4 m. They have reddish bark, lanceolate, flat, dark-green leaves 1-4 cm long and 2-3 mm broad, arranged spi...
Taxus Taxus is a genus of yews, small coniferous trees or shrubs in the yew family Taxaceae. They are relatively slow growing and can be very long-lived, and reach heights of 1-40 m, with trunk diameters of up to 4 m. They have reddish bark, lanceolate, flat, dark-green leaves 1-4 cm long and 2-3 mm broad, arranged sp...
https://www.wikidoc.org/index.php/Pacific_yew
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wikidoc
Panic
Panic Panic is a sudden fear which dominates or replaces thinking and often affects groups of people or animals. Panics typically occur in disaster situations, or violent situations (such as robbery, home invasion, a shooting rampage, etc.) which may endanger the overall health of the affected group. The word panic der...
Panic Template:Disputed Panic is a sudden fear which dominates or replaces thinking and often affects groups of people or animals. Panics typically occur in disaster situations, or violent situations (such as robbery, home invasion, a shooting rampage, etc.) which may endanger the overall health of the affected group....
https://www.wikidoc.org/index.php/Panic
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wikidoc
Pecan
Pecan # Overview The pecan (/pˈkɑːn/, /pˈkæn/, or /ˈpiːkæn/), Carya illinoinensis, is a species of hickory, native to south-central North America, in Mexico from Coahuila south to Jalisco and Veracruz, in the United States from southern Iowa, Illinois, Missouri, and Indiana to Virginia, southwestern Ohio, south throug...
Pecan Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The pecan (/[invalid input: 'icon']p[invalid input: 'ɨ']ˈkɑːn/, /p[invalid input: 'ɨ']ˈkæn/, or /ˈpiːkæn/), Carya illinoinensis, is a species of hickory, native to south-central North America, in Mexico from Coahuila south to Jalisco and Veracruz,[1]...
https://www.wikidoc.org/index.php/Pecan
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wikidoc
Penis
Penis The penis (plural penises, penes) is an external sexual organ of certain biologically male organisms. The penis is a reproductive organ and, for mammals, additionally serves as the external organ of urination. # Structure The human penis is made up of three columns of tissue: two corpora cavernosa lie next to ea...
Penis Template:Infobox Anatomy Editor-in-Chief: Joel Gelman, M.D. [1], Director of the Center for Reconstructive Urology and Associate Clinical Professor in the Department of Urology at the University of California, Irvine The penis (plural penises, penes) is an external sexual organ of certain biologically ma...
https://www.wikidoc.org/index.php/Penile_disease
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wikidoc
Renin
Renin Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that mediates the volume of extracellular fl...
Renin Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that mediates the volume of extracellular f...
https://www.wikidoc.org/index.php/Plasma_renin_activity
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wikidoc
Plunc
Plunc Palate, lung, and nasal epithelium clone protein (PLUNC) is a gene encoding a secretory protein. It is also called Secretory protein in upper respiratory tracts (SPURT). In humans, it is encoded by the BPIFA1 gene, previously called PLUNC. # Function This gene is the human homolog of murine plunc, and like the...
Plunc Palate, lung, and nasal epithelium clone protein[1] (PLUNC) is a gene encoding a secretory protein. It is also called Secretory protein in upper respiratory tracts (SPURT). In humans, it is encoded by the BPIFA1 gene, previously called PLUNC.[2][3] # Function This gene is the human homolog of murine plunc, an...
https://www.wikidoc.org/index.php/Plunc
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wikidoc
Poppy
Poppy A poppy is any of a number of showy flowers, typically with -ne per stem, belonging to the poppy family. They include a number of attractive wildflower species with showy flowers found growing singularly or in large groups; many species are also grown in gardens. Those that are grown in gardens include large plan...
Poppy Template:This A poppy is any of a number of showy flowers, typically with one per stem, belonging to the poppy family. They include a number of attractive wildflower species with showy flowers found growing singularly or in large groups; many species are also grown in gardens. Those that are grown in gardens inc...
https://www.wikidoc.org/index.php/Poppy
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wikidoc
Prion
Prion Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us to indicate your interest in serving either as an Editor-In-Chief of the entire topic ...
Prion Template:DiseaseDisorder infobox Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an...
https://www.wikidoc.org/index.php/Prion
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wikidoc
Vulva
Vulva The vulva (from Latin, vulva, plural vulvae or vulvas; see etymology) is the region of the external genital organs of the female, including the labia majora, mons pubis, labia minora, clitoris, bulb of the vestibule, vestibule of the vagina, greater and lesser vestibular glands, and vaginal orifice. The vulva ha...
Vulva Template:Infobox Anatomy The vulva (from Latin, vulva, plural vulvae or vulvas; see etymology) is the region of the external genital organs of the female, including the labia majora, mons pubis, labia minora, clitoris, bulb of the vestibule, vestibule of the vagina, greater and lesser vestibular glands, and vag...
https://www.wikidoc.org/index.php/Pudendum
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wikidoc
QSER1
QSER1 Glutamine Serine Rich Protein 1 or QSER1 is a protein encoded by the QSER1 gene. The function of this protein is currently unknown. QSER1 has one alias, FLJ21924. # Gene ## Location The QSER1 gene is found on the short arm of chromosome 11 (11p13), beginning at 32,914,792 bp and ending at 33,001,816 bp. It is 8...
QSER1 Glutamine Serine Rich Protein 1 or QSER1 is a protein encoded by the QSER1 gene.[1] The function of this protein is currently unknown. QSER1 has one alias, FLJ21924.[1] # Gene ## Location The QSER1 gene is found on the short arm of chromosome 11 (11p13), beginning at 32,914,792 bp and ending at 33,001,816 bp. ...
https://www.wikidoc.org/index.php/QSER1
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wikidoc
Qanat
Qanat A qanat (from Template:Lang-ar) or kareez (from Template:Lang-fa) is a water management system used to provide a reliable supply of water to human settlements or for irrigation in hot, arid and semi-arid climates. The widespread distribution of qanat known in different places in their local names has confounded t...
Qanat Template:Globalize A qanat (from Template:Lang-ar) or kareez (from Template:Lang-fa) is a water management system used to provide a reliable supply of water to human settlements or for irrigation in hot, arid and semi-arid climates. The widespread distribution of qanat known in different places in their local na...
https://www.wikidoc.org/index.php/Qanat
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wikidoc
Quark
Quark A quark (Template:IPAEng, Template:IPAEng or Template:IPAEng) is a generic type of physical particle that forms one of the two basic constituents of matter, the other being the lepton. Various species of quarks combine in specific ways to form protons and neutrons, in each case taking exactly three quarks to mak...
Quark Template:Tfd A quark (Template:IPAEng, Template:IPAEng or Template:IPAEng[1]) is a generic type of physical particle that forms one of the two basic constituents of matter, the other being the lepton. Various species of quarks combine in specific ways to form protons and neutrons, in each case taking exactly th...
https://www.wikidoc.org/index.php/Quark
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wikidoc
RAB23
RAB23 Ras-related protein Rab-23 is a protein that in humans is encoded by the RAB23 gene. Alternative splicing occurs at this gene locus and two transcript variants encoding the same protein have been identified. # Function RAB23 belongs to the small GTPase superfamily, Rab family. It may be involved in small GTPase ...
RAB23 Ras-related protein Rab-23 is a protein that in humans is encoded by the RAB23 gene.[1][2][3] Alternative splicing occurs at this gene locus and two transcript variants encoding the same protein have been identified.[4] # Function RAB23 belongs to the small GTPase superfamily, Rab family. It may be involved in ...
https://www.wikidoc.org/index.php/RAB23
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wikidoc
RAB27
RAB27 Rab27 is a member of the Rab subfamily of GTPases. Rab27 is post translationally modified by the addition of two geranylgeranyl groups on the two C-terminal cysteines. # Pathology Mutations that prevent the expression of Rab27 ('knock out' mutations) cause the hypopigmentation and immunodefficiency disorder know...
RAB27 Rab27 is a member of the Rab subfamily of GTPases. Rab27 is post translationally modified by the addition of two geranylgeranyl groups on the two C-terminal cysteines. # Pathology Mutations that prevent the expression of Rab27 ('knock out' mutations) cause the hypopigmentation and immunodefficiency disorder kno...
https://www.wikidoc.org/index.php/RAB27
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wikidoc
RAB7A
RAB7A Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. Ras-related protein Rab-7a is involved in endocytosis, which is a process that brings substances into a cell. The process of endocytosis works by folding the cell membrane around a substance outside of the cell (for example a pro...
RAB7A Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene.[1][2] Ras-related protein Rab-7a is involved in endocytosis, which is a process that brings substances into a cell. The process of endocytosis works by folding the cell membrane around a substance outside of the cell (for exampl...
https://www.wikidoc.org/index.php/RAB7A
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wikidoc
RAD18
RAD18 E3 ubiquitin-protein ligase RAD18 is an enzyme that in humans is encoded by the RAD18 gene. # Function The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is a ubiquitin-conjugating enzyme required for...
RAD18 E3 ubiquitin-protein ligase RAD18 is an enzyme that in humans is encoded by the RAD18 gene.[1][2][3] # Function The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is a ubiquitin-conjugating enzyme re...
https://www.wikidoc.org/index.php/RAD18
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wikidoc
RAD51
RAD51 RAD51 is a eukaryotic gene. The enzyme encoded by this gene is a member of the RAD51 protein family which assists in repair of DNA double strand breaks. RAD51 family members are homologous to the bacterial RecA, Archaeal RadA and yeast Rad51. The protein is highly conserved in most eukaryotes, from yeast to hum...
RAD51 RAD51 is a eukaryotic gene. The enzyme encoded by this gene is a member of the RAD51 protein family which assists in repair of DNA double strand breaks. RAD51 family members are homologous to the bacterial RecA, Archaeal RadA and yeast Rad51.[1][2] The protein is highly conserved in most eukaryotes, from yeast...
https://www.wikidoc.org/index.php/RAD51
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wikidoc
RAD52
RAD52 RAD52 homolog (S. cerevisiae), also known as RAD52, is a protein which in humans is encoded by the RAD52 gene. # Function The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product ...
RAD52 RAD52 homolog (S. cerevisiae), also known as RAD52, is a protein which in humans is encoded by the RAD52 gene.[1][2] # Function The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene p...
https://www.wikidoc.org/index.php/RAD52
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wikidoc
RAD9A
RAD9A Cell cycle checkpoint control protein RAD9A is a protein that in humans is encoded by the RAD9A gene.Rad9 has been shown to induce G2 arrest in the cell cycle in response to DNA damage in yeast cells. Rad9 was originally found in budding yeast cells but a human homolog has also been found and studies have suggest...
RAD9A Cell cycle checkpoint control protein RAD9A is a protein that in humans is encoded by the RAD9A gene.[1]Rad9 has been shown to induce G2 arrest in the cell cycle in response to DNA damage in yeast cells. Rad9 was originally found in budding yeast cells but a human homolog has also been found and studies have sug...
https://www.wikidoc.org/index.php/RAD9A
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wikidoc
RANKL
RANKL Receptor activator of nuclear factor kappa-.mw-parser-output .polytonic{font-family:"SBL BibLit","SBL Greek",Athena,"EB Garamond 12","Foulis Greek",Cardo,"Gentium Plus",Gentium,Garamond,"Palatino Linotype","DejaVu Sans","DejaVu Serif",FreeSerif,FreeSans,"Arial Unicode MS","Lucida Sans Unicode","Lucida Grande",Cod...
RANKL Receptor activator of nuclear factor kappa-.mw-parser-output .polytonic{font-family:"SBL BibLit","SBL Greek",Athena,"EB Garamond 12","Foulis Greek",Cardo,"Gentium Plus",Gentium,Garamond,"Palatino Linotype","DejaVu Sans","DejaVu Serif",FreeSerif,FreeSans,"Arial Unicode MS","Lucida Sans Unicode","Lucida Grande",Co...
https://www.wikidoc.org/index.php/RANKL
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wikidoc
RAPSN
RAPSN 43 kDa receptor-associated protein of the synapse (rapsyn) is a protein that in humans is encoded by the RAPSN gene. # Function This protein belongs to a family of proteins that are receptor associated proteins of the synapse. It contains a conserved cAMP-dependent protein kinase phosphorylation site. It is beli...
RAPSN 43 kDa receptor-associated protein of the synapse (rapsyn) is a protein that in humans is encoded by the RAPSN gene.[1][2] # Function This protein belongs to a family of proteins that are receptor associated proteins of the synapse. It contains a conserved cAMP-dependent protein kinase phosphorylation site. It ...
https://www.wikidoc.org/index.php/RAPSN
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wikidoc
RASD1
RASD1 Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein that in humans is encoded by the RASD1 gene on chromosome 17. It is ubiquitously expressed in many tissues and cell types. As a member of the Ras superfamily of small G-proteins, RASD1 regulates signal transduction pathways through both G proteins a...
RASD1 Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein that in humans is encoded by the RASD1 gene on chromosome 17.[1][2] It is ubiquitously expressed in many tissues and cell types.[3] As a member of the Ras superfamily of small G-proteins, RASD1 regulates signal transduction pathways through both G ...
https://www.wikidoc.org/index.php/RASD1
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wikidoc
RASEF
RASEF Ras and EF-hand domain-containing protein also known as Ras-related protein Rab-45 is a protein that in humans is encoded by the RASEF gene. The RASEF gene is located on chromosome 9 (9q21.32). # Introduction RASEF belongs to the small GTPase family, which means that it’s able to hydrolyse a molecule of GTP; kn...
RASEF Ras and EF-hand domain-containing protein also known as Ras-related protein Rab-45 is a protein that in humans is encoded by the RASEF gene.[1] The RASEF gene is located on chromosome 9 (9q21.32).[2] # Introduction RASEF belongs to the small GTPase family, which means that it’s able to hydrolyse a molecule of ...
https://www.wikidoc.org/index.php/RASEF
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wikidoc
RBBP4
RBBP4 Histone-binding protein RBBP4 (also known as RbAp48, or NURF55) is a protein that in humans is encoded by the RBBP4 gene. # Function This gene encodes a ubiquitously expressed nuclear protein that belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histon...
RBBP4 Histone-binding protein RBBP4 (also known as RbAp48, or NURF55) is a protein that in humans is encoded by the RBBP4 gene.[1][2] # Function This gene encodes a ubiquitously expressed nuclear protein that belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in...
https://www.wikidoc.org/index.php/RBBP4
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wikidoc
RBBP6
RBBP6 Retinoblastoma-binding protein 6 is a protein that in humans is encoded by the RBBP6 gene. # Function The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulate...
RBBP6 Retinoblastoma-binding protein 6 is a protein that in humans is encoded by the RBBP6 gene.[1][2][3] # Function The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylatio...
https://www.wikidoc.org/index.php/RBBP6
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wikidoc
RBBP7
RBBP7 Histone-binding protein RBBP7 is a protein that in humans is encoded by the RBBP7 gene. # Function This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which re...
RBBP7 Histone-binding protein RBBP7 is a protein that in humans is encoded by the RBBP7 gene.[1] # Function This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, whic...
https://www.wikidoc.org/index.php/RBBP7
e7727371ea0ec919bb6371056b5b1e58ec6d3a19
wikidoc
RBCK1
RBCK1 RanBP-type and C3HC4-type zinc finger-containing protein 1 is a protein that in humans is encoded by the RBCK1 gene. The protein encoded by this gene is similar to mouse UIP28/UbcM4 interacting protein. Alternative splicing has been observed at this locus, resulting in distinct isoforms. # Clinical significance ...
RBCK1 RanBP-type and C3HC4-type zinc finger-containing protein 1 is a protein that in humans is encoded by the RBCK1 gene.[1] The protein encoded by this gene is similar to mouse UIP28/UbcM4 interacting protein. Alternative splicing has been observed at this locus, resulting in distinct isoforms.[1] # Clinical signif...
https://www.wikidoc.org/index.php/RBCK1
eb6bc25b4277fe528c0639e07a921eb1441b7312
wikidoc
RBM39
RBM39 RNA-binding protein 39 is a protein that in humans is encoded by the RBM39 gene. # Function The protein encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it colocalizes with core spliceosomal proteins. Studies of a mouse protein with h...
RBM39 RNA-binding protein 39 is a protein that in humans is encoded by the RBM39 gene.[1][2] # Function The protein encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it colocalizes with core spliceosomal proteins. Studies of a mouse protein...
https://www.wikidoc.org/index.php/RBM39
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wikidoc
RBM8A
RBM8A RNA-binding protein 8A is a protein that in humans is encoded by the RBM8A gene. This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, includi...
RBM8A RNA-binding protein 8A is a protein that in humans is encoded by the RBM8A gene.[1][2] This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, ...
https://www.wikidoc.org/index.php/RBM8A
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wikidoc
RBMS1
RBMS1 RNA-binding motif, single-stranded-interacting protein 1 is a protein that in humans is encoded by the RBMS1 gene. # Function This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus se...
RBMS1 RNA-binding motif, single-stranded-interacting protein 1 is a protein that in humans is encoded by the RBMS1 gene.[1][2][3][4] # Function This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein...
https://www.wikidoc.org/index.php/RBMS1
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wikidoc
RBPMS
RBPMS RNA-binding protein with multiple splicing is a protein that in humans is encoded by the RBPMS gene. # Function This gene encodes a member of the RRM family of RNA-binding proteins. The RRM domain is between 80-100 amino acids in length and family members contain one to four copies of the domain. The RRM domain ...
RBPMS RNA-binding protein with multiple splicing is a protein that in humans is encoded by the RBPMS gene.[1][2] # Function This gene encodes a member of the RRM family of RNA-binding proteins. The RRM domain is between 80-100 amino acids in length and family members contain one to four copies of the domain. The RRM ...
https://www.wikidoc.org/index.php/RBPMS
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wikidoc
RCHY1
RCHY1 RING finger and CHY zinc finger domain-containing protein 1 is a protein that in humans is encoded by the RCHY1 gene. # Function The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is onc...
RCHY1 RING finger and CHY zinc finger domain-containing protein 1 is a protein that in humans is encoded by the RCHY1 gene.[1] # Function The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is...
https://www.wikidoc.org/index.php/RCHY1
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wikidoc
RDH11
RDH11 Retinol dehydrogenase 11 is an enzyme that in humans is encoded by the RDH11 gene. RHD11, a member of the short-chain dehydrogenase/reductase (SDR) superfamily of oxidoreductases, is expressed at high levels in prostate epithelium, and its expression is regulated by androgens. # Clinical significance Mutations i...
RDH11 Retinol dehydrogenase 11 is an enzyme that in humans is encoded by the RDH11 gene.[1][2][3][4] RHD11, a member of the short-chain dehydrogenase/reductase (SDR) superfamily of oxidoreductases, is expressed at high levels in prostate epithelium, and its expression is regulated by androgens.[supplied by OMIM][4] #...
https://www.wikidoc.org/index.php/RDH11
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wikidoc
RDH13
RDH13 Retinol dehydrogenase 13 (all-trans/9-cis) is a protein that in humans is encoded by the RDH13 gene. This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the...
RDH13 Retinol dehydrogenase 13 (all-trans/9-cis) is a protein that in humans is encoded by the RDH13 gene. This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect th...
https://www.wikidoc.org/index.php/RDH13
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wikidoc
RECQL
RECQL ATP-dependent DNA helicase Q1 is an enzyme that in humans is encoded by the RECQL gene. The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some mem...
RECQL ATP-dependent DNA helicase Q1 is an enzyme that in humans is encoded by the RECQL gene.[1][2][3] The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair...
https://www.wikidoc.org/index.php/RECQL
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wikidoc
REEP2
REEP2 Receptor expression-enhancing protein 2 is a protein that in humans is encoded by the REEP2 gene. # Function The protein encoded by REEP2 belongs to a family of proteins with receptor enhancing expression capabilities, including possible enhancement of G protein-coupled receptors. The REEP2 protein shows a restr...
REEP2 Receptor expression-enhancing protein 2 is a protein that in humans is encoded by the REEP2 gene.[1][2] # Function The protein encoded by REEP2 belongs to a family of proteins with receptor enhancing expression capabilities, including possible enhancement of G protein-coupled receptors[3]. The REEP2 protein sho...
https://www.wikidoc.org/index.php/REEP2
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wikidoc
REG3A
REG3A Regenerating islet-derived protein 3 alpha (or Regenerating islet-derived protein III-alpha) formerly known as HIP/PAP (Hepatocarcinoma-Intestine-Pancreas/Pancreatitis-Associated Protein) and peptide 23 is a protein that in humans is encoded by the REG3A gene. This gene encodes a pancreatic secretory protein that...
REG3A Regenerating islet-derived protein 3 alpha (or Regenerating islet-derived protein III-alpha) formerly known as HIP/PAP (Hepatocarcinoma-Intestine-Pancreas/Pancreatitis-Associated Protein) and peptide 23[1] is a protein that in humans is encoded by the REG3A gene.[2][3] This gene encodes a pancreatic secretory pr...
https://www.wikidoc.org/index.php/REG3A
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wikidoc
REG3G
REG3G Regenerating islet-derived protein 3 gamma (also Regenerating islet-derived protein III-gamma) is a protein that in humans is encoded by the REG3G gene. Intestinal paneth cells produce REG3G (or REG3 gamma) via stimulation of toll-like receptors (TLRs) by pathogen-associated molecular patterns (PAMPs). REG3 gamma...
REG3G Regenerating islet-derived protein 3 gamma (also Regenerating islet-derived protein III-gamma) is a protein that in humans is encoded by the REG3G gene.[1][2][3][4] Intestinal paneth cells produce REG3G (or REG3 gamma) via stimulation of toll-like receptors (TLRs) by pathogen-associated molecular patterns (PAMPs...
https://www.wikidoc.org/index.php/REG3G
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wikidoc
REPS2
REPS2 RalBP1-associated Eps domain-containing protein 2 is a protein that in humans is encoded by the REPS2 gene. # Function The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that func...
REPS2 RalBP1-associated Eps domain-containing protein 2 is a protein that in humans is encoded by the REPS2 gene.[1][2][3] # Function The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein...
https://www.wikidoc.org/index.php/REPS2
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wikidoc
RGS13
RGS13 Regulator of G-protein signaling 13 is a protein that in humans is encoded by the RGS13 gene. RGS 13 is a member of R4 subfamily of RGS (Regulators of G Protein Signaling) proteins which have only short peptide sequences flanking the RGS domain. RGS 13 suppresses the immunoglobulin E- mediated allergic responses....
RGS13 Regulator of G-protein signaling 13 is a protein that in humans is encoded by the RGS13 gene.[1][2] RGS 13 is a member of R4 subfamily of RGS (Regulators of G Protein Signaling) proteins which have only short peptide sequences flanking the RGS domain. RGS 13 suppresses the immunoglobulin E- mediated allergic res...
https://www.wikidoc.org/index.php/RGS13
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wikidoc
RGS14
RGS14 Regulator of G-protein signaling 14 (RGS14) is a protein that in humans is encoded by the RGS14 gene. # Function RGS14 is a member of the regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco motif. The protein attenuates the signa...
RGS14 Regulator of G-protein signaling 14 (RGS14) is a protein that in humans is encoded by the RGS14 gene.[1] # Function RGS14 is a member of the regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco motif. The protein attenuates the s...
https://www.wikidoc.org/index.php/RGS14
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wikidoc
RGS17
RGS17 Regulator of G-protein signaling 17 is a protein that in humans is encoded by the RGS17 gene. # Function This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the ...
RGS17 Regulator of G-protein signaling 17 is a protein that in humans is encoded by the RGS17 gene.[1][2] # Function This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuat...
https://www.wikidoc.org/index.php/RGS17
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wikidoc
RGS19
RGS19 Regulator of G-protein signaling 19 is a protein that in humans is encoded by the RGS19 gene. G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosi...
RGS19 Regulator of G-protein signaling 19 is a protein that in humans is encoded by the RGS19 gene.[1][2] G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a ...
https://www.wikidoc.org/index.php/RGS19
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wikidoc
RGS20
RGS20 Regulator of G-protein signaling 20 is a protein that in humans is encoded by the RGS20 gene. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNA...
RGS20 Regulator of G-protein signaling 20 is a protein that in humans is encoded by the RGS20 gene.[1][2][3] Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and G...
https://www.wikidoc.org/index.php/RGS20
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wikidoc
RHOT1
RHOT1 Mitochondrial Rho GTPase 1 (MIRO1) is an enzyme that in humans is encoded by the RHOT1 gene on chromosome 17. As a Miro protein isoform, the protein facilitates mitochondrial transport by attaching the mitochondria to the motor/adaptor complex. Through its key role in mitochondrial transport, RHOT1 is involved in...
RHOT1 Mitochondrial Rho GTPase 1 (MIRO1) is an enzyme that in humans is encoded by the RHOT1 gene on chromosome 17.[1][2] As a Miro protein isoform, the protein facilitates mitochondrial transport by attaching the mitochondria to the motor/adaptor complex.[3] Through its key role in mitochondrial transport, RHOT1 is i...
https://www.wikidoc.org/index.php/RHOT1
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wikidoc
RING1
RING1 E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene. # Function This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as...
RING1 E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene.[1][2] # Function This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can...
https://www.wikidoc.org/index.php/RING1
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wikidoc
RIPK1
RIPK1 Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is an enzyme that in humans is encoded by the RIPK1 gene, which is located on chromosome 6. This protein belongs to the Receptor Interacting Protein (RIP) kinases family, which consists of 7 members, RIPK1 being the first member of the family. RIPK1 i...
RIPK1 Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is an enzyme that in humans is encoded by the RIPK1 gene, which is located on chromosome 6.[1][2][3] This protein belongs to the Receptor Interacting Protein (RIP) kinases family, which consists of 7 members, RIPK1 being the first member of the famil...
https://www.wikidoc.org/index.php/RIPK1
5cfb63971e58039b7bfdc4d569fec3a450b058de
wikidoc
RIPK3
RIPK3 Receptor-interacting serine/threonine-protein kinase 3 is an enzyme that in humans is encoded by the RIPK3 gene. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The enc...
RIPK3 Receptor-interacting serine/threonine-protein kinase 3 is an enzyme that in humans is encoded by the RIPK3 gene.[1][2][3][4] The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family mem...
https://www.wikidoc.org/index.php/RIPK3
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wikidoc
RIPK5
RIPK5 Dual serine/threonine and tyrosine protein kinase is an enzyme that in humans is encoded by the DSTYK gene. This protein is also known as the Dusty protein kinase and the Receptor interacting protein 5 (RIP5). This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tis...
RIPK5 Dual serine/threonine and tyrosine protein kinase is an enzyme that in humans is encoded by the DSTYK gene.[1][2] This protein is also known as the Dusty protein kinase and the Receptor interacting protein 5 (RIP5). This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multi...
https://www.wikidoc.org/index.php/RIPK5
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wikidoc
RMDN3
RMDN3 Regulator of microtubule dynamics protein 3 (RMDN3), more commonly known as Protein tyrosine phosphatase interacting protein 51 (PTPIP51), is a protein that in humans is encoded by the RMDN3 gene on chromosome 15. This protein contributes to multiple biological functions, including cellular differentiation, proli...
RMDN3 Regulator of microtubule dynamics protein 3 (RMDN3), more commonly known as Protein tyrosine phosphatase interacting protein 51 (PTPIP51), is a protein that in humans is encoded by the RMDN3 gene on chromosome 15.[1][2] This protein contributes to multiple biological functions, including cellular differentiation...
https://www.wikidoc.org/index.php/RMDN3
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wikidoc
RNF10
RNF10 RING finger protein 10 is a protein that in humans is encoded by the RNF10 gene. # Function The protein encoded by this gene contains a ring finger motif, which is known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. EST data suggests the existe...
RNF10 RING finger protein 10 is a protein that in humans is encoded by the RNF10 gene.[1] # Function The protein encoded by this gene contains a ring finger motif, which is known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. EST data suggests the ex...
https://www.wikidoc.org/index.php/RNF10
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wikidoc
ROBO1
ROBO1 Roundabout homolog 1 is a protein that in humans is encoded by the ROBO1 gene. # Function Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants...
ROBO1 Roundabout homolog 1 is a protein that in humans is encoded by the ROBO1 gene.[1][2][3] # Function Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoa...
https://www.wikidoc.org/index.php/ROBO1
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wikidoc
ROCK1
ROCK1 ROCK1 is a protein serine/threonine kinase also known as rho-associated, coiled-coil-containing protein kinase 1. Other common names are ROKβ and P160ROCK. ROCK1 is a major downstream effecter of the small GTPase RhoA and is a regulator of the actomyosin cytoskeleton which promotes contractile force generation. R...
ROCK1 ROCK1 is a protein serine/threonine kinase also known as rho-associated, coiled-coil-containing protein kinase 1. Other common names are ROKβ and P160ROCK. ROCK1 is a major downstream effecter of the small GTPase RhoA and is a regulator of the actomyosin cytoskeleton which promotes contractile force generation.[...
https://www.wikidoc.org/index.php/ROCK1
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wikidoc
RPAP2
RPAP2 RNA polymerase II associated protein 2, also known as RPAP2, is a human gene. # Model organisms Model organisms have been used in the study of RPAP2 function. A conditional knockout mouse line, called Rpap2tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throug...
RPAP2 RNA polymerase II associated protein 2, also known as RPAP2, is a human gene.[1] # Model organisms Model organisms have been used in the study of RPAP2 function. A conditional knockout mouse line, called Rpap2tm1a(KOMP)Wtsi[6][7] was generated as part of the International Knockout Mouse Consortium program — a h...
https://www.wikidoc.org/index.php/RPAP2
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wikidoc
RPE65
RPE65 Retinal pigment epithelium-specific 65 kDa protein, also known as retinoid isomerohydrolase, is an enzyme of the vertebrate visual cycle that is encoded in humans by the RPE65 gene. RPE65 is expressed in the retinal pigment epithelium (RPE, a layer of epithelial cells that nourish the photoreceptor cells) and is ...
RPE65 Retinal pigment epithelium-specific 65 kDa protein, also known as retinoid isomerohydrolase, is an enzyme of the vertebrate visual cycle that is encoded in humans by the RPE65 gene.[1][2] RPE65 is expressed in the retinal pigment epithelium (RPE, a layer of epithelial cells that nourish the photoreceptor cells) ...
https://www.wikidoc.org/index.php/RPE65
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wikidoc
RPL36
RPL36 60S ribosomal protein L36 is a protein that in humans is encoded by the RPL36 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This ...
RPL36 60S ribosomal protein L36 is a protein that in humans is encoded by the RPL36 gene.[1] Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. T...
https://www.wikidoc.org/index.php/RPL36
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wikidoc
RPTOR
RPTOR Regulatory-associated protein of mTOR also known as raptor or KIAA1303 is an adapter protein that is encoded in humans by the RPTOR gene. Two mRNAs from the gene have been identified that encode proteins of 1335 (isoform 1) and 1177 (isoform 2) amino acids long. # Gene and expression The human gene is located o...
RPTOR Regulatory-associated protein of mTOR also known as raptor or KIAA1303 is an adapter protein that is encoded in humans by the RPTOR gene.[1][2][3] Two mRNAs from the gene have been identified that encode proteins of 1335 (isoform 1) and 1177 (isoform 2) amino acids long. # Gene and expression The human gene is...
https://www.wikidoc.org/index.php/RPTOR
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wikidoc
RRBP1
RRBP1 Ribosome-binding protein 1, also referred to as p180, is a protein that in humans is encoded by the RRBP1 gene. RRBP1 is a membrane-bound protein found in the endoplasmic reticulum (ER). It was originally identified as the ribosome receptor for the ER, however several groups later demonstrated that this activity ...
RRBP1 Ribosome-binding protein 1, also referred to as p180, is a protein that in humans is encoded by the RRBP1 gene.[1][2] RRBP1 is a membrane-bound protein found in the endoplasmic reticulum (ER). It was originally identified as the ribosome receptor for the ER,[3] however several groups later demonstrated that this...
https://www.wikidoc.org/index.php/RRBP1
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wikidoc
RRM2B
RRM2B Ribonucleoside-diphosphate reductase subunit M2 B is an enzyme that in humans is encoded by the RRM2B gene. The gene encoding the RRM2B protein is located on chromosome 8, at position 8q23.1. The gene and its products are also known by designations MTDPS8A, MTDPS8B, and p53R2. # Function RRM2B codes for one of t...
RRM2B Ribonucleoside-diphosphate reductase subunit M2 B is an enzyme that in humans is encoded by the RRM2B gene.[1][2][3][4] The gene encoding the RRM2B protein is located on chromosome 8, at position 8q23.1. The gene and its products are also known by designations MTDPS8A, MTDPS8B, and p53R2. # Function RRM2B codes...
https://www.wikidoc.org/index.php/RRM2B
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wikidoc
RSPO1
RSPO1 R-spondin-1 is a secreted protein that in humans is encoded by the Rspo1 gene, found on chromosome 1. In humans, it interacts with WNT4 in the process of female sex development. Loss of function can cause female to male sex reversal. Furthermore, it promotes canonical WNT/β catenin signaling. # Structure The ...
RSPO1 R-spondin-1 is a secreted protein that in humans is encoded by the Rspo1 gene, found on chromosome 1.[1] In humans, it interacts with WNT4 in the process of female sex development. Loss of function can cause female to male sex reversal.[2] Furthermore, it promotes canonical WNT/β catenin signaling.[3] # Stru...
https://www.wikidoc.org/index.php/RSPO1
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wikidoc
RSPO3
RSPO3 R-spondin-3 is a protein that in humans is encoded by the RSPO3 gene. # Function This gene encodes a member of the thrombospondin type 1 repeat supergene family. In addition, the protein contains a furin-like cysteine-rich region. Furin-like repeat domains have been found in a variety of eukaryotic proteins invo...
RSPO3 R-spondin-3 is a protein that in humans is encoded by the RSPO3 gene.[1][2][3] # Function This gene encodes a member of the thrombospondin type 1 repeat supergene family. In addition, the protein contains a furin-like cysteine-rich region. Furin-like repeat domains have been found in a variety of eukaryotic pro...
https://www.wikidoc.org/index.php/RSPO3
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wikidoc
RUFY2
RUFY2 RUN and FYVE domain containing 2 (RUFY2) is a protein that in humans is encoded by the RUFY2 gene. The RUFY2 gene is named for two of its domains, the RUN domain and FYVE domains. RUFY2 is a member of the RUFY family of proteins that include RUFY1, RUFY2, RUFY3, and RUFY4. RUFY2 protein has a dynamic role in endo...
RUFY2 RUN and FYVE domain containing 2 (RUFY2) is a protein that in humans is encoded by the RUFY2 gene.[1] The RUFY2 gene is named for two of its domains, the RUN domain and FYVE domains. RUFY2 is a member of the RUFY family of proteins that include RUFY1, RUFY2, RUFY3, and RUFY4. RUFY2 protein has a dynamic role in ...
https://www.wikidoc.org/index.php/RUFY2
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wikidoc
RUNX1
RUNX1 Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) is a protein that in humans is encoded by the RUNX1 gene. RUNX1 is a transcription factor that regulates the differentiation of hematopoietic stem cells into mature bloo...
RUNX1 Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) is a protein that in humans is encoded by the RUNX1 gene.[1][2] RUNX1 is a transcription factor that regulates the differentiation of hematopoietic stem cells into matu...
https://www.wikidoc.org/index.php/RUNX1
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wikidoc
RUNX2
RUNX2 Runt-related transcription factor 2 (RUNX2) also known as core-binding factor subunit alpha-1 (CBF-alpha-1) is a protein that in humans is encoded by the RUNX2 gene. RUNX2 is a key transcription factor associated with osteoblast differentiation. It has also been suggested that Runx2 plays a cell proliferation reg...
RUNX2 Runt-related transcription factor 2 (RUNX2) also known as core-binding factor subunit alpha-1 (CBF-alpha-1) is a protein that in humans is encoded by the RUNX2 gene. RUNX2 is a key transcription factor associated with osteoblast differentiation. It has also been suggested that Runx2 plays a cell proliferation re...
https://www.wikidoc.org/index.php/RUNX2
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wikidoc
RUNX3
RUNX3 Runt-related transcription factor 3 is a protein that in humans is encoded by the RUNX3 gene. # Function This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-YGYGGT-3' foun...
RUNX3 Runt-related transcription factor 3 is a protein that in humans is encoded by the RUNX3 gene.[1] # Function This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-YGYGGT-3' ...
https://www.wikidoc.org/index.php/RUNX3
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wikidoc
Rad50
Rad50 DNA repair protein RAD50, also known as RAD50, is a protein that in humans is encoded by the RAD50 gene. # Function The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1 (also kn...
Rad50 DNA repair protein RAD50, also known as RAD50, is a protein that in humans is encoded by the RAD50 gene.[1] # Function The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1 (als...
https://www.wikidoc.org/index.php/Rad50
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wikidoc
Ramus
Ramus Ramus can refer to: - A portion of a bone (from Latin ramus, "branch"), as in the Ramus mandibulæ or Superior pubic ramus - A nerve ramus such as the Dorsal ramus of spinal nerve - An arterial branch such as the ramus intermedius in the heart
Ramus Ramus can refer to: - A portion of a bone (from Latin ramus, "branch"), as in the Ramus mandibulæ or Superior pubic ramus - A nerve ramus such as the Dorsal ramus of spinal nerve - An arterial branch such as the ramus intermedius in the heart
https://www.wikidoc.org/index.php/Ramus
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wikidoc
Raphe
Raphe A raphe has different uses: # In science Pronounced "RAY-fee" Template:IPA), it is most commonly used when describing diatoms, seeds, and human anatomy. In the field of anatomy, the term refers to a continuous ridge of tissue. There are several different significant raphes: - The perineal raphe extends from the ...
Raphe Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] A raphe has different uses: # In science Pronounced "RAY-fee" Template:IPA), it is most commonly used when describing diatoms, seeds, and human anatomy. In the field of anatomy, the term refers to a continuous ridge of tissue. There are several different signif...
https://www.wikidoc.org/index.php/Raphe
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wikidoc
Rayon
Rayon # Overview Rayon is a manufactured regenerated cellulosic fiber. Rayon is produced from naturally occurring polymers and therefore it is not a truly synthetic fiber, nor is it a natural fiber. # History ## Nitrocellulose The fact that Nitrocellulose is soluble in organic solvents such as ether and acetone, mad...
Rayon Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Rayon is a manufactured regenerated cellulosic fiber. Rayon is produced from naturally occurring polymers and therefore it is not a truly synthetic fiber, nor is it a natural fiber. # History ## Nitrocellulose The fact that Nitrocellulose is solubl...
https://www.wikidoc.org/index.php/Rayon
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wikidoc
Relay
Relay A relay is an electrical switch that opens and closes under the control of another electrical circuit. In the original form, the switch is operated by an electromagnet to open or close one or many sets of contacts. It was invented by Joseph Henry in 1835. Because a relay is able to control an output circuit -f h...
Relay Template:Otheruses1 A relay is an electrical switch that opens and closes under the control of another electrical circuit. In the original form, the switch is operated by an electromagnet to open or close one or many sets of contacts. It was invented by Joseph Henry in 1835. Because a relay is able to control an...
https://www.wikidoc.org/index.php/Relay
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wikidoc
Ricin
Ricin The protein ricin (pronounced Template:IPA) is a toxin extracted from the castor bean (Ricinus communis). Ricin has an average lethal dose in humans of 0.2 milligrams (1/5,000th of a gram), though some sources give higher figures. # Toxicity Ricin is poisonous if inhaled, injected, or ingested, acting as a toxin...
Ricin The protein ricin (pronounced Template:IPA) is a toxin extracted from the castor bean (Ricinus communis). Ricin has an average lethal dose in humans of 0.2 milligrams (1/5,000th of a gram), though some sources give higher figures.[1] # Toxicity Ricin is poisonous if inhaled, injected, or ingested, acting as a t...
https://www.wikidoc.org/index.php/Ricin
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wikidoc
Rosin
Rosin Rosin, formerly called colophony or Greek pitch (Pix græca), is a solid form of resin obtained from pines and some other plants, mostly conifers, produced by heating fresh liquid resin to vaporize the volatile liquid terpene components. It is semi-transparent and varies in color from yellow to black. At room temp...
Rosin Rosin, formerly called colophony or Greek pitch (Pix græca), is a solid form of resin obtained from pines and some other plants, mostly conifers, produced by heating fresh liquid resin to vaporize the volatile liquid terpene components. It is semi-transparent and varies in color from yellow to black. At room tem...
https://www.wikidoc.org/index.php/Rosin