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9682112a41bc67a2767bf4ba72a9c30f48e4935f | wikidoc | Rumen | Rumen
# Overview
The rumen, also known as the fardingbag or paunch forms the larger part of the reticulorumen, which is the first chamber in the alimentary canal of ruminant animals. It serves as the primary site for microbial fermentation of ingested feed. The smaller part of the reticulorumen is the reticulum, which... | Rumen
# Overview
The rumen, also known as the fardingbag or paunch forms the larger part of the reticulorumen, which is the first chamber in the alimentary canal of ruminant animals. It serves as the primary site for microbial fermentation of ingested feed. The smaller part of the reticulorumen is the reticulum, which... | https://www.wikidoc.org/index.php/Rumen | |
8e1045bb3977b918089470eab806fc7a8ebf438d | wikidoc | Rutin | Rutin
# Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pa... | Rutin
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]
# Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be... | https://www.wikidoc.org/index.php/Rutin | |
31c4306ad5e74c8f24c0e33a1baa71529aa7aebe | wikidoc | S100B | S100B
S100 calcium-binding protein B (S100B) is a protein of the S-100 protein family.
S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 me... | S100B
S100 calcium-binding protein B (S100B) is a protein of the S-100 protein family.
S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 m... | https://www.wikidoc.org/index.php/S100B | |
20cfa2cf4c58fe169e1ffb4ab0f7b45efe2fe2b8 | wikidoc | S100P | S100P
S100 calcium-binding protein P (S100P) is a protein that in humans is encoded by the S100P gene.
# Function
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells... | S100P
S100 calcium-binding protein P (S100P) is a protein that in humans is encoded by the S100P gene.[1][2][3]
# Function
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide rang... | https://www.wikidoc.org/index.php/S100P | |
ce0cf134014900166932e20fc78d739e7387bab8 | wikidoc | S1PR1 | S1PR1
Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 is a G-protein-coupled receptor which binds the bioactive signaling molecule sphingosine 1-phosphate (S1P). S1PR1 belongs to a sphin... | S1PR1
Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 is a G-protein-coupled receptor which binds the bioactive signaling molecule sphingosine 1-phosphate (S1P). S1PR1 belongs to a sphi... | https://www.wikidoc.org/index.php/S1PR1 | |
6921f1c555f50ad4e76f40b8c1c96ab7ef92f53f | wikidoc | SALL1 | SALL1
Sal-like 1 (Drosophila), also known as SALL1, is a protein which in humans is encoded by the SALL1 gene. As the full name suggests, it is one of the human versions of the spalt (sal) gene known in Drosophila.
# Function
The protein encoded by this gene is a zinc finger transcriptional repressor and may be part o... | SALL1
Sal-like 1 (Drosophila), also known as SALL1, is a protein which in humans is encoded by the SALL1 gene.[1][2] As the full name suggests, it is one of the human versions of the spalt (sal) gene known in Drosophila.
# Function
The protein encoded by this gene is a zinc finger transcriptional repressor and may be... | https://www.wikidoc.org/index.php/SALL1 | |
a905340d3bc0e08e7ae7d4186e52b0d530437c72 | wikidoc | SALL4 | SALL4
Sal-like protein 4 (SALL4) is a transcription factor encoded by a member of the Spalt-like (SALL) gene family, SALL4. The SALL genes were identified based on their sequence homology to Spalt, which is a homeotic gene originally cloned in Drosophila melanogaster that is important for terminal trunk structure forma... | SALL4
Sal-like protein 4 (SALL4) is a transcription factor encoded by a member of the Spalt-like (SALL) gene family, SALL4.[1][2] The SALL genes were identified based on their sequence homology to Spalt, which is a homeotic gene originally cloned in Drosophila melanogaster that is important for terminal trunk structur... | https://www.wikidoc.org/index.php/SALL4 | |
a7e43af3b7da3c87e1dc5f988ba2e928467651fa | wikidoc | SAP30 | SAP30
Sin3A-associated protein, 30kDa, also known as SAP30, is a protein which in humans is encoded by the SAP30 gene.
# Function
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by t... | SAP30
Sin3A-associated protein, 30kDa, also known as SAP30, is a protein which in humans is encoded by the SAP30 gene.[1]
# Function
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded ... | https://www.wikidoc.org/index.php/SAP30 | |
740a15880dafd33cfb752135f38c37b8936e6829 | wikidoc | SAR1B | SAR1B
SAR1 gene homolog B (S. cerevisiae), also known as SAR1B, is a protein which in humans is encoded by the SAR1B gene.
# Function
SAR1B belongs to the Sar1-ADP ribosylation factor family of small GTPases, which govern the intracellular trafficking of proteins in coat protein (COP)-coated vesicles.
# Clinical sign... | SAR1B
SAR1 gene homolog B (S. cerevisiae), also known as SAR1B, is a protein which in humans is encoded by the SAR1B gene.[1][2]
# Function
SAR1B belongs to the Sar1-ADP ribosylation factor family of small GTPases,[3] which govern the intracellular trafficking of proteins in coat protein (COP)-coated vesicles.[4]
# ... | https://www.wikidoc.org/index.php/SAR1B | |
fdc704882f3ae7e1609b36aca6c05b6583ebc5db | wikidoc | SART3 | SART3
Squamous cell carcinoma antigen recognized by T-cells 3 is a protein that in humans is encoded by the SART3 gene.
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cy... | SART3
Squamous cell carcinoma antigen recognized by T-cells 3 is a protein that in humans is encoded by the SART3 gene.[1][1][2][2][3]
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and t... | https://www.wikidoc.org/index.php/SART3 | |
043073fb2f19273d458edec827dd25301f00f852 | wikidoc | SASS6 | SASS6
Spindle assembly abnormal protein 6 homolog (SAS-6) is a protein that in humans is encoded by the SASS6 gene.
# Function
SAS-6 is necessary for centrosome duplication and functions during procentriole formation; SAS-6 functions to ensure that each centriole seeds the formation of a single procentriole per cell c... | SASS6
Spindle assembly abnormal protein 6 homolog (SAS-6) is a protein that in humans is encoded by the SASS6 gene.[1][2][3]
# Function
SAS-6 is necessary for centrosome duplication and functions during procentriole formation; SAS-6 functions to ensure that each centriole seeds the formation of a single procentriole ... | https://www.wikidoc.org/index.php/SASS6 | |
49e566702a1a442aca8e4ac827f49047e8be4fea | wikidoc | SATB2 | SATB2
Special AT-rich sequence-binding protein 2 (SATB2) also known as DNA-binding protein SATB2 is a protein that in humans is encoded by the SATB2 gene. SATB2 is a DNA-binding protein that specifically binds nuclear matrix attachment regions and is involved in transcriptional regulation and chromatin remodeling. SAT... | SATB2
Special AT-rich sequence-binding protein 2 (SATB2) also known as DNA-binding protein SATB2 is a protein that in humans is encoded by the SATB2 gene.[1] SATB2 is a DNA-binding protein that specifically binds nuclear matrix attachment regions and is involved in transcriptional regulation and chromatin remodeling.[... | https://www.wikidoc.org/index.php/SATB2 | |
e2886366d7a8c814322207b2bd563d18f5de036f | wikidoc | SCN1B | SCN1B
Sodium channel subunit beta-1 is a protein that in humans is encoded by the SCN1B gene.
Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits... | SCN1B
Sodium channel subunit beta-1 is a protein that in humans is encoded by the SCN1B gene.[1][2]
Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta s... | https://www.wikidoc.org/index.php/SCN1B | |
39c45edaedaa4a5eb74dffb973c84c3257b30a1a | wikidoc | SCN3A | SCN3A
Sodium channel, voltage-gated, type III, alpha subunit (SCN3A) is a protein that in humans is encoded by the Nav1.3 gene.
# Function
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. Th... | SCN3A
Sodium channel, voltage-gated, type III, alpha subunit (SCN3A) is a protein that in humans is encoded by the Nav1.3 gene.[1]
# Function
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits... | https://www.wikidoc.org/index.php/SCN3A | |
ff6ed1f38c484ebb5200965ca4024b9a0065049d | wikidoc | SCN8A | SCN8A
Sodium channel, voltage gated, type VIII, alpha subunit also known as SCN8A or Nav1.6 is a membrane protein encoded by the SCN8A gene. Nav1.6 is one sodium channel isoform and is the primary voltage-gated sodium channel at the nodes of Ranvier. The channels are highly concentrated in sensory and motor axons in t... | SCN8A
Sodium channel, voltage gated, type VIII, alpha subunit also known as SCN8A or Nav1.6 is a membrane protein encoded by the SCN8A gene.[1] Nav1.6 is one sodium channel isoform and is the primary voltage-gated sodium channel at the nodes of Ranvier. The channels are highly concentrated in sensory and motor axons ... | https://www.wikidoc.org/index.php/SCN8A | |
c3eb8fda8fbbe8f1809df0d8efbf7b1d0784abfd | wikidoc | SCRIB | SCRIB
SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. It was originally isolated in Drosophila melanogaster in a pathway (also known as the Scribble complex) with DLGAP5 (Discs large) and LLGL1 (Lethal giant larvae) as a tumor... | SCRIB
SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene.[1][2] It was originally isolated in Drosophila melanogaster in a pathway (also known as the Scribble complex) with DLGAP5 (Discs large) and LLGL1 (Lethal giant larvae) as ... | https://www.wikidoc.org/index.php/SCRIB | |
3de65e1f8962bcb79a4a232765cdc2f3f11f703a | wikidoc | SCYL1 | SCYL1
SCY1-like 1 (S. cerevisiae), also known as SCYL1, is a human gene which is highly conserved throughout evolution.
# Function
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalyti... | SCYL1
SCY1-like 1 (S. cerevisiae), also known as SCYL1, is a human gene which is highly conserved throughout evolution.[1][2]
# Function
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be c... | https://www.wikidoc.org/index.php/SCYL1 | |
1cdc9e83a35d8e42fafe750eff0108e9b76273d5 | wikidoc | SEC63 | SEC63
Translocation protein SEC63 homolog is a protein that in humans is encoded by the SEC63 gene.
# Function
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with... | SEC63
Translocation protein SEC63 homolog is a protein that in humans is encoded by the SEC63 gene.[1][2][3]
# Function
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be assoc... | https://www.wikidoc.org/index.php/SEC63 | |
9bbaed6d52f8043854634e0a4a9ab5917893bb7e | wikidoc | SENP1 | SENP1
Sentrin-specific protease 1 is an enzyme that in humans is encoded by the SENP1 gene.
# General
So far there are six SUMO proteases in humans that have been designated SENP1-3 and SENP5-7 (sentrin/SUMO-specific protease).1 The six proteases possess a conserved C-terminal domain which are variable in size, and wi... | SENP1
Sentrin-specific protease 1 is an enzyme that in humans is encoded by the SENP1 gene.[1][2][3]
# General
So far there are six SUMO proteases in humans that have been designated SENP1-3 and SENP5-7 (sentrin/SUMO-specific protease).1 The six proteases possess a conserved C-terminal domain which are variable in si... | https://www.wikidoc.org/index.php/SENP1 | |
99f5de698b84f4e4fd18a19e400d6bd253c6c953 | wikidoc | SENP3 | SENP3
SUMO1/sentrin/SMT3 specific peptidase 3, also known as SENP3, is a protein which in humans is encoded by the SENP3 gene.
SENP3 together with SENP5, belongs to the Ulp1 branch in yeast and localize to nucleolus through B23/NPM1. SENP3 is associated and regulated by B23/nucleophosmin/NPM1 and involved in the regula... | SENP3
SUMO1/sentrin/SMT3 specific peptidase 3, also known as SENP3, is a protein which in humans is encoded by the SENP3 gene.[1][2]
SENP3 together with SENP5, belongs to the Ulp1 branch in yeast and localize to nucleolus through B23/NPM1. SENP3 is associated and regulated by B23/nucleophosmin/NPM1 and involved in the... | https://www.wikidoc.org/index.php/SENP3 | |
7d08f26cc1c0d3a0f3cb0339e1e8b7654718ccb1 | wikidoc | SEP15 | SEP15
15 kDa selenoprotein is a protein that in humans is encoded by the SEP15 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
# Function
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine... | SEP15
15 kDa selenoprotein is a protein that in humans is encoded by the SEP15 gene.[1] Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
# Function
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocyst... | https://www.wikidoc.org/index.php/SEP15 | |
043d855580ba1f6327eddac4d90623c5b57eaca5 | wikidoc | SEPN1 | SEPN1
Selenoprotein N is a protein that in humans is encoded by the SEPN1 gene.
# Function
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes... | SEPN1
Selenoprotein N is a protein that in humans is encoded by the SEPN1 gene.[1][2]
# Function
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotei... | https://www.wikidoc.org/index.php/SEPN1 | |
523fbd833cd0d9adae44aed573f81dfd29143ad6 | wikidoc | SEPT6 | SEPT6
Septin-6 is a protein that in humans is encoded by the SEPT6 gene.
# Function
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identifi... | SEPT6
Septin-6 is a protein that in humans is encoded by the SEPT6 gene.[1][2][3]
# Function
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has bee... | https://www.wikidoc.org/index.php/SEPT6 | |
a64a5665bf32d7dfcf87119b7df6574caf09bd34 | wikidoc | SEPT9 | SEPT9
Septin-9 is a protein that in humans is encoded by the SEPT9 gene.
# Interactions
SEPT9 has been shown to interact with SEPT2 and SEPT7.
# Function
Along with AHNAK, eIF4E and S100A11, SEPT9 has been shown to be essential for pseudopod protrusion, tumor cell migration and invasion.
# Clinical significance
The ... | SEPT9
Septin-9 is a protein that in humans is encoded by the SEPT9 gene.[1][2][3]
# Interactions
SEPT9 has been shown to interact with SEPT2[4] and SEPT7.[4]
# Function
Along with AHNAK, eIF4E and S100A11, SEPT9 has been shown to be essential for pseudopod protrusion, tumor cell migration and invasion.[5]
# Clinica... | https://www.wikidoc.org/index.php/SEPT9 | |
ae61e3ddba007d731939e2cdb5b6e390b6ab8d7f | wikidoc | SESN1 | SESN1
Sestrin 1, also known as p53-regulated protein PA26, is a protein that in humans is encoded by the SESN1 gene.
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress.
The encoded prote... | SESN1
Sestrin 1, also known as p53-regulated protein PA26, is a protein that in humans is encoded by the SESN1 gene.
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress.
The encoded prot... | https://www.wikidoc.org/index.php/SESN1 | |
9c5ac7e281a3a5dd5dc5463495ba7470a5c7009d | wikidoc | SESN2 | SESN2
Sestrin-2 also known as Hi95 is a protein that in humans is encoded by the SESN2 gene.
# Function
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to differe... | SESN2
Sestrin-2 also known as Hi95 is a protein that in humans is encoded by the SESN2 gene.[1][2][3]
# Function
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response ... | https://www.wikidoc.org/index.php/SESN2 | |
fd83e7d45cf3a0c2b0b0451e37ff1035d8cde273 | wikidoc | SETD2 | SETD2
SET domain containing 2 is an enzyme that in humans is encoded by the SETD2 gene.
# Function
SETD2 protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activatio... | SETD2
SET domain containing 2 is an enzyme that in humans is encoded by the SETD2 gene.[1][2][3]
# Function
SETD2 protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional... | https://www.wikidoc.org/index.php/SETD2 | |
4eb4f12eabe45bda4a6536de624838f38e75d130 | wikidoc | SF3B1 | SF3B1
Splicing factor 3B subunit 1 is a protein that in humans is encoded by the SF3B1 gene.
# Function
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The s... | SF3B1
Splicing factor 3B subunit 1 is a protein that in humans is encoded by the SF3B1 gene.[1][2]
# Function
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP)... | https://www.wikidoc.org/index.php/SF3B1 | |
9c75602b42574d67ed17d53af1a7d6a71ade53bb | wikidoc | SF3B2 | SF3B2
Splicing factor 3B subunit 2 is a protein that in humans is encoded by the SF3B2 gene.
# Function
This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The s... | SF3B2
Splicing factor 3B subunit 2 is a protein that in humans is encoded by the SF3B2 gene.[1][2]
# Function
This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP)... | https://www.wikidoc.org/index.php/SF3B2 | |
4cbebb207d5b6437478f0e11aa58c72535cde507 | wikidoc | SF3B3 | SF3B3
Splicing factor 3B subunit 3 is a protein that in humans is encoded by the SF3B3 gene.
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing fact... | SF3B3
Splicing factor 3B subunit 3 is a protein that in humans is encoded by the SF3B3 gene.[1][2]
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splici... | https://www.wikidoc.org/index.php/SF3B3 | |
623e8b6a80c7afd26980518a86c8a9f560d4a35f | wikidoc | SF3B4 | SF3B4
Splicing factor 3B subunit 4 is a protein that in humans is encoded by the SF3B4 gene.
# Function
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the presplic... | SF3B4
Splicing factor 3B subunit 4 is a protein that in humans is encoded by the SF3B4 gene.[1][2]
# Function
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the p... | https://www.wikidoc.org/index.php/SF3B4 | |
7feefbdabd696717af94a97d7dd87798879aed12 | wikidoc | SFRP4 | SFRP4
Secreted frizzled-related protein 4 is a protein that in humans is encoded by the SFRP4 gene.
# Function
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulator... | SFRP4
Secreted frizzled-related protein 4 is a protein that in humans is encoded by the SFRP4 gene.[1][2]
# Function
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble mo... | https://www.wikidoc.org/index.php/SFRP4 | |
414e9746888593c75487494454e4dd765d10ebfa | wikidoc | SFRS7 | SFRS7
Serine/arginine-rich splicing factor 7 (SRSF7) also known as splicing factor, arginine/serine-rich 7 (SFRS7) or splicing factor 9G8 is a protein that in humans is encoded by the SRSF7 gene.
# Function
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factor... | SFRS7
Serine/arginine-rich splicing factor 7 (SRSF7) also known as splicing factor, arginine/serine-rich 7 (SFRS7) or splicing factor 9G8 is a protein that in humans is encoded by the SRSF7 gene.[1]
# Function
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing fa... | https://www.wikidoc.org/index.php/SFRS7 | |
1ebc11b23773546e4e713f6ecc45feb081c21c29 | wikidoc | SGLT2 | SGLT2
The sodium/glucose cotransporter 2 (SGLT2) is a protein that in humans is encoded by the SLC5A2 (solute carrier family 5 (sodium/glucose cotransporter)) gene.
# Function
SGLT2 is a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. SGLT2 is the major cotrans... | SGLT2
The sodium/glucose cotransporter 2 (SGLT2) is a protein that in humans is encoded by the SLC5A2 (solute carrier family 5 (sodium/glucose cotransporter)) gene.[1]
# Function
SGLT2 is a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. SGLT2 is the major cot... | https://www.wikidoc.org/index.php/SGLT2 | |
03655b7fef06c4d9b6269a6e6fb9cba74491f60c | wikidoc | SGMS1 | SGMS1
Phosphatidylcholine:ceramide cholinephosphotransferase 1 is an enzyme that in humans is encoded by the SGMS1 gene.
# Function
The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain.
# Model organisms
Model organisms have been used... | SGMS1
Phosphatidylcholine:ceramide cholinephosphotransferase 1 is an enzyme that in humans is encoded by the SGMS1 gene.[1][2][3]
# Function
The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain.[3]
# Model organisms
Model organisms h... | https://www.wikidoc.org/index.php/SGMS1 | |
8256f1a9a27647f57e1cc50241c75ca2346c03e4 | wikidoc | SGOL1 | SGOL1
Shugoshin-like 1 is a protein that in humans is encoded by the SGOL1 gene.
# Model organisms
Model organisms have been used in the study of SGOL1 function. A conditional knockout mouse line, called Sgol1tm1a(EUCOMM)Wtsi has been generated.
Male and female animals underwent a standardized phenotypic screen to det... | SGOL1
Shugoshin-like 1 is a protein that in humans is encoded by the SGOL1 gene.[1][2]
# Model organisms
Model organisms have been used in the study of SGOL1 function. A conditional knockout mouse line, called Sgol1tm1a(EUCOMM)Wtsi[8][9] has been generated.[10][11][12]
Male and female animals underwent a standardized... | https://www.wikidoc.org/index.php/SGOL1 | |
9ea0c3fb6789921ccc66ffc5f03ad9cbb335154b | wikidoc | SGOL2 | SGOL2
Shugoshin-like 2 (S. pombe), also known as SGOL2, is a protein which in humans is encoded by the SGOL2 gene.
# Function
Shugoshin-like 2 (SGOL2) is one of the two mammalian orthologs of the Shugoshin/Mei-S322 family of proteins that regulate sister chromatid cohesion by protecting the integrity of a multiprotein... | SGOL2
Shugoshin-like 2 (S. pombe), also known as SGOL2, is a protein which in humans is encoded by the SGOL2 gene.[1][2]
# Function
Shugoshin-like 2 (SGOL2) is one of the two mammalian orthologs of the Shugoshin/Mei-S322 family of proteins that regulate sister chromatid cohesion by protecting the integrity of a multi... | https://www.wikidoc.org/index.php/SGOL2 | |
1dcaab100c877a78f68e654ae7aeebf75f3850f3 | wikidoc | SH2B2 | SH2B2
SH2B adapter protein 2 is a protein that in humans is encoded by the SH2B2 gene.
# Function
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt lymphoma cell lines, it is tyrosine phosphorylated in response to B cell recepto... | SH2B2
SH2B adapter protein 2 is a protein that in humans is encoded by the SH2B2 gene.[1][2]
# Function
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt lymphoma cell lines, it is tyrosine phosphorylated in response to B cell ... | https://www.wikidoc.org/index.php/SH2B2 | |
ef7cfff3753ff43cde39cc718bfedff006c67fcb | wikidoc | SH2B3 | SH2B3
SH2B adapter protein 3 (SH2B3), also known as lymphocyte adapter protein (LNK), is a protein that in humans is encoded by the SH2B3 gene on chromosome 12.
SH2B adapter protein 3 is a protein that in humans is encoded by the SH2B3 gene on chromosome 12. It is ubiquitously expressed in many tissues and cell types. ... | SH2B3
SH2B adapter protein 3 (SH2B3), also known as lymphocyte adapter protein (LNK), is a protein that in humans is encoded by the SH2B3 gene on chromosome 12.[1][2]
SH2B adapter protein 3 is a protein that in humans is encoded by the SH2B3 gene on chromosome 12. It is ubiquitously expressed in many tissues and cell ... | https://www.wikidoc.org/index.php/SH2B3 | |
02f308fee42bdd1719d7fac1bb814b915993eec0 | wikidoc | SHLD1 | SHLD1
SHLD1 or shieldin complex subunit 1 is a gene on chromosome 20. The C20orf196 gene encodes an mRNA that is 1,763 base pairs long, and a protein that is 205 amino acids long.
# Function
C20orf196 is involved in the DNA repair network. Gupta et al. identified C20orf196 as part of a vertebrate-specific protein comp... | SHLD1
SHLD1 or shieldin complex subunit 1 is a gene on chromosome 20.[1] The C20orf196 gene encodes an mRNA that is 1,763 base pairs long, and a protein that is 205 amino acids long.[1]
# Function
C20orf196 is involved in the DNA repair network. Gupta et al. identified C20orf196 as part of a vertebrate-specific prote... | https://www.wikidoc.org/index.php/SHLD1 | |
435fcbba9d3d81a696065751944dd390d1663459 | wikidoc | SHOX2 | SHOX2
Short stature homeobox 2, also known as homeobox protein Og12X or paired-related homeobox protein SHOT, is a protein that in humans is encoded by the SHOX2 gene.
# Function
SHOX2 is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA-bindin... | SHOX2
Short stature homeobox 2, also known as homeobox protein Og12X or paired-related homeobox protein SHOT, is a protein that in humans is encoded by the SHOX2 gene.[1][2][3]
# Function
SHOX2 is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a ... | https://www.wikidoc.org/index.php/SHOX2 | |
29bd6daa666f6ee5f586cc29fdf23cd88b4b7087 | wikidoc | SIAH2 | SIAH2
E3 ubiquitin-protein ligase SIAH2 is an enzyme that in humans is encoded by the SIAH2 gene.
# Function
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific protein... | SIAH2
E3 ubiquitin-protein ligase SIAH2 is an enzyme that in humans is encoded by the SIAH2 gene.[1][2]
# Function
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific ... | https://www.wikidoc.org/index.php/SIAH2 | |
533d87d9831451860ac473bdfdf589a10367ec02 | wikidoc | SIRT2 | SIRT2
NAD-dependent deacetylase sirtuin-2 is an enzyme that in humans is encoded by the SIRT2 gene. SIRT2 is an NAD+ (nicotinamide adenine dinucleotide)-dependent deacetylase. Studies of this protein have often been divergent, highlighting the dependence of pleiotropic effects of SIRT2 on cellular context. The natural ... | SIRT2
NAD-dependent deacetylase sirtuin-2 is an enzyme that in humans is encoded by the SIRT2 gene.[1][2][3] SIRT2 is an NAD+ (nicotinamide adenine dinucleotide)-dependent deacetylase. Studies of this protein have often been divergent, highlighting the dependence of pleiotropic effects of SIRT2 on cellular context. Th... | https://www.wikidoc.org/index.php/SIRT2 | |
6ca801b593ee4d29a3d9b7fadad24542a58a2349 | wikidoc | SIRT4 | SIRT4
Sirtuin 4, also known as SIRT4, is a protein which in humans is encoded by the SIRT4 gene.
# Function
This gene encodes a member of the sirtuin family of proteins which are homologs of the Sir2 gene in budding yeast. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four c... | SIRT4
Sirtuin 4, also known as SIRT4, is a protein which in humans is encoded by the SIRT4 gene.[1][2]
# Function
This gene encodes a member of the sirtuin family of proteins which are homologs of the Sir2 gene in budding yeast. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into... | https://www.wikidoc.org/index.php/SIRT4 | |
dd11ad84992131e32ed471dd9cdc3f2128d8ae7f | wikidoc | SIRT5 | SIRT5
Sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae), also known as SIRT5 is a protein which in humans in encoded by the SIRT5 gene and in other species by the orthologous Sirt5 gene.
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Membe... | SIRT5
Sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae), also known as SIRT5 is a protein which in humans in encoded by the SIRT5 gene and in other species by the orthologous Sirt5 gene.[1]
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. M... | https://www.wikidoc.org/index.php/SIRT5 | |
dc69934f000e3e080f99c395e7790baa7ad9a6ff | wikidoc | SIRT6 | SIRT6
Sirtuin-6 (SIRT6) is a stress responsive protein deacetylase and mono-ADP ribosyltransferase enzyme encoded by the SIRT6 gene. SIRT6 functions in multiple molecular pathways related to aging, including DNA repair, telomere maintenance, glycolysis and inflammation.
# Function
Studies in mice have revealed that Si... | SIRT6
Sirtuin-6 (SIRT6) is a stress responsive protein deacetylase and mono-ADP ribosyltransferase enzyme encoded by the SIRT6 gene.[1][2] SIRT6 functions in multiple molecular pathways related to aging, including DNA repair, telomere maintenance, glycolysis and inflammation.[1]
# Function
Studies in mice have reveal... | https://www.wikidoc.org/index.php/SIRT6 | |
bb7286432576d5cd45f463e5b0cead8fbe39a1ba | wikidoc | SIRT7 | SIRT7
NAD-dependent deacetylase sirtuin-7 is an enzyme that in humans is encoded by the SIRT7 gene.
# Function
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The fu... | SIRT7
NAD-dependent deacetylase sirtuin-7 is an enzyme that in humans is encoded by the SIRT7 gene.[1][2][3]
# Function
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four class... | https://www.wikidoc.org/index.php/SIRT7 | |
661c90a3221ee59146a676fbe58ca404c9ff224d | wikidoc | SIVA1 | SIVA1
Apoptosis regulatory protein Siva is a protein that in humans is encoded by the SIVA1 gene.
This gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasm... | SIVA1
Apoptosis regulatory protein Siva is a protein that in humans is encoded by the SIVA1 gene.[1][2]
This gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cy... | https://www.wikidoc.org/index.php/SIVA1 | |
bcfd3439bb6f2810a4e26ddd2e8294f3e7601a5b | wikidoc | SKAP1 | SKAP1
Src kinase-associated phosphoprotein 1 is an adapter protein that in humans is encoded by the SKAP1 gene.
This gene encodes a T cell adapter protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded prot... | SKAP1
Src kinase-associated phosphoprotein 1 is an adapter protein that in humans is encoded by the SKAP1 gene.[1][2]
This gene encodes a T cell adapter protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encod... | https://www.wikidoc.org/index.php/SKAP1 | |
0ee80c85e5cea6b6b9905387ed25fe5898c89948 | wikidoc | SMC1A | SMC1A
Structural maintenance of chromosomes protein 1A is a protein that in humans is encoded by the SMC1A gene.
# Function
Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion.... | SMC1A
Structural maintenance of chromosomes protein 1A is a protein that in humans is encoded by the SMC1A gene.[1][2]
# Function
Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid co... | https://www.wikidoc.org/index.php/SMC1A | |
f407f72bae0856d06e06154d2a14f5096c48115a | wikidoc | SMCO4 | SMCO4
SMCO4 (Single-pass membrane protein with coiled-coil domains 4) is a human gene that encodes the FN5 protein. The FN5 protein is a single-pass transmembrane protein, which means that one end of the protein will remain in the cytoplasm, while the other end of the protein is exposed to the interior of the cell.
#... | SMCO4
SMCO4 (Single-pass membrane protein with coiled-coil domains 4) is a human gene that encodes the FN5 protein. The FN5 protein is a single-pass transmembrane protein, which means that one end of the protein will remain in the cytoplasm, while the other end of the protein is exposed to the interior of the cell.
... | https://www.wikidoc.org/index.php/SMCO4 | |
e3a07e4bf84f6d3bf6d283756f5c9d518a6d0ea4 | wikidoc | SMOC2 | SMOC2
SPARC-related modular calcium-binding protein 2 is a protein that in humans is encoded by the SMOC2 gene.
# Clinical relevance
This gene has been shown mutated in clinical cases of major dental developmental defects.
Brachycephalic dogs show a shortening of the snout along with a widening of the hard palate. Thi... | SMOC2
SPARC-related modular calcium-binding protein 2 is a protein that in humans is encoded by the SMOC2 gene.[1][2]
# Clinical relevance
This gene has been shown mutated in clinical cases of major dental developmental defects.[3]
Brachycephalic dogs show a shortening of the snout along with a widening of the hard p... | https://www.wikidoc.org/index.php/SMOC2 | |
d5661ccb113694f24925b7c0f8ca3246e8751cb8 | wikidoc | SMYD3 | SMYD3
SET and MYND domain-containing protein 3 is a protein that in humans is encoded by the SMYD3 gene.
# Function
SMYD3 is a histone methyltransferase that plays a role in transcriptional regulation as a member of an RNA polymerase complex.
# Model organisms
Model organisms have been used in the study of SMYD3 func... | SMYD3
SET and MYND domain-containing protein 3 is a protein that in humans is encoded by the SMYD3 gene.[1]
# Function
SMYD3 is a histone methyltransferase that plays a role in transcriptional regulation as a member of an RNA polymerase complex.[1]
# Model organisms
Model organisms have been used in the study of SMY... | https://www.wikidoc.org/index.php/SMYD3 | |
e5670a7341faa8f36b4c6d053504690c15cfde3c | wikidoc | SMYD4 | SMYD4
SET and MYND domain-containing protein 4 is a protein that in humans is encoded by the SMYD4 gene.
# Model organisms
Model organisms have been used in the study of SMYD4 function. A conditional knockout mouse line, called Smyd4tm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consortium ... | SMYD4
SET and MYND domain-containing protein 4 is a protein that in humans is encoded by the SMYD4 gene.[1][2]
# Model organisms
Model organisms have been used in the study of SMYD4 function. A conditional knockout mouse line, called Smyd4tm1a(EUCOMM)Wtsi[7][8] was generated as part of the International Knockout Mous... | https://www.wikidoc.org/index.php/SMYD4 | |
08affc0d6c2e97ee9e3acbf5821f7a5239a39c25 | wikidoc | SNAI1 | SNAI1
Zinc finger protein SNAI1 (sometimes referred to as Snail) is a protein that in humans is encoded by the SNAI1 gene. Snail is a family of transcription factors that promote the repression of the adhesion molecule E-cadherin to regulate epithelial to mesenchymal transition (EMT) during embryonic development.
# Fu... | SNAI1
Zinc finger protein SNAI1 (sometimes referred to as Snail) is a protein that in humans is encoded by the SNAI1 gene.[1][2] Snail is a family of transcription factors that promote the repression of the adhesion molecule E-cadherin to regulate epithelial to mesenchymal transition (EMT) during embryonic development... | https://www.wikidoc.org/index.php/SNAI1 | |
9c2185fad9be430a9d019a650724c5f256b5647d | wikidoc | SNAI2 | SNAI2
Zinc finger protein SNAI2 is a protein that in humans is encoded by the SNAI2 gene.
# Function
This gene encodes a member of the Snail superfamily of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cad... | SNAI2
Zinc finger protein SNAI2 is a protein that in humans is encoded by the SNAI2 gene.[1][2][3]
# Function
This gene encodes a member of the Snail superfamily of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to rep... | https://www.wikidoc.org/index.php/SNAI2 | |
61a0e7395466d71a5c952f613c75c0fddaa23a94 | wikidoc | SNX17 | SNX17
Sorting nexin-17 is a protein that in humans is encoded by the SNX17 gene.
# Function
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain... | SNX17
Sorting nexin-17 is a protein that in humans is encoded by the SNX17 gene.[1][2][3]
# Function
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does n... | https://www.wikidoc.org/index.php/SNX17 | |
fce1b82ba83b923360457a128794300de5c36ce5 | wikidoc | SOAT1 | SOAT1
Sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1, also known as SOAT1, is an enzyme that in humans is encoded by the SOAT1 gene.
# Function
Acyl-coenzyme A:cholesterol acyltransferase (EC 2.3.1.26) is an intracellular protein located in the endoplasmic reticulum that forms cholesterol es... | SOAT1
Sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1, also known as SOAT1, is an enzyme that in humans is encoded by the SOAT1 gene.[1]
# Function
Acyl-coenzyme A:cholesterol acyltransferase (EC 2.3.1.26) is an intracellular protein located in the endoplasmic reticulum that forms cholestero... | https://www.wikidoc.org/index.php/SOAT1 | |
af8044da2d2c9364986551e0f7d317f0a1d92c32 | wikidoc | SOCS2 | SOCS2
Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene.
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The... | SOCS2
Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene.[1][2][3]
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine sign... | https://www.wikidoc.org/index.php/SOCS2 | |
b2cebf40f1427cc89e45cf9515dc10fe503e7330 | wikidoc | SOCS3 | SOCS3
Suppressor of cytokine signaling 3 (SOCS3 or SOCS-3) is a protein that in humans is encoded by the SOCS3 gene.
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytok... | SOCS3
Suppressor of cytokine signaling 3 (SOCS3 or SOCS-3) is a protein that in humans is encoded by the SOCS3 gene.[1][2]
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators o... | https://www.wikidoc.org/index.php/SOCS3 | |
56c39aa97c915185c788fd74554fa6cbae1820b3 | wikidoc | SOCS7 | SOCS7
Suppressor of cytokine signaling 7 is a protein that in humans is encoded by the SOCS7 gene.
# Model organisms
Model organisms have been used in the study of SOCS7 function. A conditional knockout mouse line, called Socs7tm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consortium progra... | SOCS7
Suppressor of cytokine signaling 7 is a protein that in humans is encoded by the SOCS7 gene.[1][2][3]
# Model organisms
Model organisms have been used in the study of SOCS7 function. A conditional knockout mouse line, called Socs7tm1a(EUCOMM)Wtsi[9][10] was generated as part of the International Knockout Mouse ... | https://www.wikidoc.org/index.php/SOCS7 | |
bf8d62277a88266b11d13a7622eadb8aa7855fc0 | wikidoc | SOGA2 | SOGA2
SOGA2, also known as Suppressor of glucose autophagy associated 2 or CCDC165, is a protein that in humans is encoded by the SOGA2 gene.
SOGA2 has two human paralogs, SOGA1 and SOGA3.
In humans, the gene coding sequence is 151,349 base pairs long, with an mRNA of 6092 base pairs, and a protein sequence of 1586 ami... | SOGA2
SOGA2, also known as Suppressor of glucose autophagy associated 2 or CCDC165, is a protein that in humans is encoded by the SOGA2 gene.[1][2]
SOGA2 has two human paralogs, SOGA1 and SOGA3.[3][4]
In humans, the gene coding sequence is 151,349 base pairs long, with an mRNA of 6092 base pairs, and a protein sequenc... | https://www.wikidoc.org/index.php/SOGA2 | |
bdbefb55d2230344dd3991ad43cd7e7f03429ad8 | wikidoc | SORL1 | SORL1
Sortilin-related receptor, L(DLR class) A repeats containing is a protein that in humans is encoded by the SORL1 gene.
SORL1 (also known as SORLA, SORLA1, or LR11) is a neuronal apolipoprotein E receptor, the gene for which is predominantly expressed in the central nervous system.
# Clinical significance
Mutatio... | SORL1
Sortilin-related receptor, L(DLR class) A repeats containing is a protein that in humans is encoded by the SORL1 gene.[1]
SORL1 (also known as SORLA, SORLA1, or LR11) is a neuronal apolipoprotein E receptor, the gene for which is predominantly expressed in the central nervous system.[2]
# Clinical significance
... | https://www.wikidoc.org/index.php/SORL1 | |
6cb80e22ea06f2b6de74539280bd235dd8ac61d4 | wikidoc | SOX10 | SOX10
Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene.
# Function
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and determination of cell fate. The encoded protein act as a transcripti... | SOX10
Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene.[1][2][3][4]
# Function
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and determination of cell fate. The encoded protein act as ... | https://www.wikidoc.org/index.php/SOX10 | |
0c022f5ba02ceaaa3d6e57469f702c76ad3a374a | wikidoc | SOX11 | SOX11
Transcription factor SOX-11 is a protein that in humans is encoded by the SOX11 gene.
# Function
This intronless gene encodes a member of the group C SOX (SRY-related HMG-box) transcription factor family involved in the regulation of embryonic development and in the determination of the cell fate. The encoded pr... | SOX11
Transcription factor SOX-11 is a protein that in humans is encoded by the SOX11 gene.[1][2][3]
# Function
This intronless gene encodes a member of the group C SOX (SRY-related HMG-box) transcription factor family involved in the regulation of embryonic development and in the determination of the cell fate. The ... | https://www.wikidoc.org/index.php/SOX11 | |
4e8b27227de61ba3afbbef05ba272e6df21bed25 | wikidoc | SOX13 | SOX13
Transcription factor SOX-13 is a protein that in humans is encoded by the SOX13 gene.
# Function
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a ... | SOX13
Transcription factor SOX-13 is a protein that in humans is encoded by the SOX13 gene.[1][2]
# Function
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may ac... | https://www.wikidoc.org/index.php/SOX13 | |
8ad404271e1896f9ad4bd822278ef20639e5068f | wikidoc | SOX21 | SOX21
Transcription factor SOX-21 is a protein that in humans is encoded by the SOX21 gene. It is a member of the Sox gene family of transcription factors.
# Function
In the chick embryo, Sox21 promotes neuronal cellular differentiation by counteracting the activity of Sox1, Sox2, and Sox3, which maintain neural cells... | SOX21
Transcription factor SOX-21 is a protein that in humans is encoded by the SOX21 gene.[1][2] It is a member of the Sox gene family of transcription factors.
# Function
In the chick embryo, Sox21 promotes neuronal cellular differentiation by counteracting the activity of Sox1, Sox2, and Sox3, which maintain neura... | https://www.wikidoc.org/index.php/SOX21 | |
0951adfb5f59d203783d102f612d568681b8eb8e | wikidoc | SPDEF | SPDEF
SAM pointed domain-containing Ets transcription factor is a protein that in humans is encoded by the SPDEF gene.
PDEF is an ETS transcription factor expressed in prostate epithelial cells. It acts as an androgen-independent transactivator of PSA (MIM 176820) expression.
# Interactions
SPDEF has been shown to int... | SPDEF
SAM pointed domain-containing Ets transcription factor is a protein that in humans is encoded by the SPDEF gene.[1][2][3]
PDEF is an ETS transcription factor expressed in prostate epithelial cells. It acts as an androgen-independent transactivator of PSA (MIM 176820) expression.[supplied by OMIM][3]
# Interacti... | https://www.wikidoc.org/index.php/SPDEF | |
dfc75a7e581d35184637f0da221e8fd700904693 | wikidoc | SPG20 | SPG20
Spartin is a protein that in humans is encoded by the SPG20 gene.
This gene encodes a protein that contains a MIT (Microtubule Interacting and Trafficking molecule) domain. This protein may be involved in endosomal trafficking, microtubule dynamics, or both functions. Frameshift mutations associated with this gen... | SPG20
Spartin is a protein that in humans is encoded by the SPG20 gene.[1][2][3]
This gene encodes a protein that contains a MIT (Microtubule Interacting and Trafficking molecule) domain. This protein may be involved in endosomal trafficking, microtubule dynamics, or both functions. Frameshift mutations associated wit... | https://www.wikidoc.org/index.php/SPG20 | |
c2d0e51e5aaf7463b0b2e872fc1dff8b9f07d30a | wikidoc | SPNS2 | SPNS2
Spinster homolog 2 (Drosophila) is a protein that in humans is encoded by the SPNS2 gene.
# Model organisms
Model organisms have been used in the study of SPNS2 function. A conditional knockout mouse line, called Spns2tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consortium program — a... | SPNS2
Spinster homolog 2 (Drosophila) is a protein that in humans is encoded by the SPNS2 gene.[1]
# Model organisms
Model organisms have been used in the study of SPNS2 function. A conditional knockout mouse line, called Spns2tm1a(KOMP)Wtsi[12][13] was generated as part of the International Knockout Mouse Consortium... | https://www.wikidoc.org/index.php/SPNS2 | |
25147d74351ddfe1de4e6fe54d5f6c34b3dc4ecb | wikidoc | SPRY2 | SPRY2
Sprouty homolog 2 (Drosophila), also known as SPRY2, is a protein which in humans is encoded by the SPRY2 gene.
# Function
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine ... | SPRY2
Sprouty homolog 2 (Drosophila), also known as SPRY2, is a protein which in humans is encoded by the SPRY2 gene.[1]
# Function
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyros... | https://www.wikidoc.org/index.php/SPRY2 | |
b789265cdb12c9c0c2a1689bd34c283a77a46718 | wikidoc | SRPK1 | SRPK1
Serine/threonine-protein kinase SRPK1 is an enzyme that in humans is encoded by the SRPK1 gene.
# Function
This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play... | SRPK1
Serine/threonine-protein kinase SRPK1 is an enzyme that in humans is encoded by the SRPK1 gene.[1][2][3]
# Function
This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thoug... | https://www.wikidoc.org/index.php/SRPK1 | |
75a11b95eed634ec290a5f7f2e3ab9cc3ca4a960 | wikidoc | STAG2 | STAG2
Cohesin subunit SA-2 is a protein that in humans is encoded by the STAG2 gene.
# Function
STAG2 is part of the cohesin complex, which is a structure that holds the sister chromatids together after DNA replication. STAG2 has been shown to interact with STAG1.
# Role in Disease
Of the cohesin complex, STAG2 is t... | STAG2
Cohesin subunit SA-2 is a protein that in humans is encoded by the STAG2 gene.[1][2]
# Function
STAG2 is part of the cohesin complex, which is a structure that holds the sister chromatids together after DNA replication.[3] STAG2 has been shown to interact with STAG1.[4]
# Role in Disease
Of the cohesin comple... | https://www.wikidoc.org/index.php/STAG2 | |
0efa7bd4613810f17be9d64b0f7ec1f06cb016c7 | wikidoc | STAM2 | STAM2
Signal transducing adapter molecule 2 is a protein that in humans is encoded by the STAM2 gene.
# Function
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine... | STAM2
Signal transducing adapter molecule 2 is a protein that in humans is encoded by the STAM2 gene.[1][2][3]
# Function
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunorecepto... | https://www.wikidoc.org/index.php/STAM2 | |
15ddd42e8aadffd3e01d79940a16cc524d996bbf | wikidoc | STAT1 | STAT1
Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. It is a member of the STAT protein family.
# Function
All STAT molecules are phosphorylated by receptor associated kinases, that causes activation, dimerization by forming homo- or h... | STAT1
Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. It is a member of the STAT protein family.
# Function
All STAT molecules are phosphorylated by receptor associated kinases, that causes activation, dimerization by forming homo- or ... | https://www.wikidoc.org/index.php/STAT1 | |
c8b7087959860c81d9b0c6c6286efb2947325dc5 | wikidoc | STAT3 | STAT3
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene. It is a member of the STAT protein family.
# Function
STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT3 is phosphorylated by receptor-a... | STAT3
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.[1] It is a member of the STAT protein family.
# Function
STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT3 is phosphorylated by recept... | https://www.wikidoc.org/index.php/STAT3 | |
cab180f99c6f6e86de0c4fe27e7dfb58de595fe1 | wikidoc | STAT4 | STAT4
Signal transducer and activator of transcription 4 (STAT4) is a transcription factor belonging to the STAT protein family. It is required for the development of Th1 cells from naive CD4+ T cells and IFN-γ production in response to IL-12.
# Structure
Human as well murine STAT4 genes lie next to STAT1 gene locus ... | STAT4
Signal transducer and activator of transcription 4 (STAT4) is a transcription factor belonging to the STAT protein family.[1] It is required for the development of Th1 cells from naive CD4+ T cells[2] and IFN-γ production in response to IL-12.[3]
# Structure
Human as well murine STAT4 genes lie next to STAT1 g... | https://www.wikidoc.org/index.php/STAT4 | |
c21dcb07b638193c5f16bc17210c09ade56a479a | wikidoc | STAT5 | STAT5
Signal transducer and activator of transcription 5 (STAT5) refers to two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins. Though STAT5A and STAT5B are encoded by separate genes, the proteins are 90% identical at the amino acid level. STAT5 proteins are invo... | STAT5
Signal transducer and activator of transcription 5 (STAT5) refers to two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins. Though STAT5A and STAT5B are encoded by separate genes, the proteins are 90% identical at the amino acid level.[1] STAT5 proteins are ... | https://www.wikidoc.org/index.php/STAT5 | |
2ca036c62ed2500e83d8b006d5b1b791582d3021 | wikidoc | STAT6 | STAT6
Signal transducer and activator of transcription 6 (STAT6) is a human gene. The protein encoded by this gene is a member of the STAT family of transcription factors.
In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or hete... | STAT6
Signal transducer and activator of transcription 6 (STAT6) is a human gene. The protein encoded by this gene is a member of the STAT family of transcription factors.[1][2]
In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- ... | https://www.wikidoc.org/index.php/STAT6 | |
421644f8cc49952b9a7a33f2dad39a903d8a86de | wikidoc | STIM1 | STIM1
Stromal interaction molecule 1 is a protein that in humans is encoded by the STIM1 gene. STIM1 has a single transmembrane domain, and is localized to the endoplasmic reticulum, and to a lesser extent to the plasma membrane.
Even though the protein has been identified earlier, its function was unknown until recent... | STIM1
Stromal interaction molecule 1 is a protein that in humans is encoded by the STIM1 gene.[1][2][3] STIM1 has a single transmembrane domain, and is localized to the endoplasmic reticulum, and to a lesser extent to the plasma membrane.[4]
Even though the protein has been identified earlier, its function was unknown... | https://www.wikidoc.org/index.php/STIM1 | |
a78eb55004407c3bff6c957efecb62cb528cbde8 | wikidoc | STIM2 | STIM2
Stromal interaction molecule 2 (STIM2) is a protein that in humans is encoded by the STIM2 gene.
This gene is a member of the stromal interaction molecule (STIM) family which comprises only two members together with its homologue STIM1, and likely arose from a common ancestral gene. They encode type 1 transmembra... | STIM2
Stromal interaction molecule 2 (STIM2) is a protein that in humans is encoded by the STIM2 gene.[1][2]
This gene is a member of the stromal interaction molecule (STIM) family which comprises only two members together with its homologue STIM1, and likely arose from a common ancestral gene. They encode type 1 tran... | https://www.wikidoc.org/index.php/STIM2 | |
502aa14fab7503017ab20fba158703f8cc13df6c | wikidoc | STK11 | STK11
Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a protein kinase that in humans is encoded by the STK11 gene.
# Expression
Testosterone and DHT treatment of murine 3T3-L1 or human SGBS adipocytes for 24 h significantly decreased the mRNA expression ... | STK11
Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a protein kinase that in humans is encoded by the STK11 gene.[1]
# Expression
Testosterone and DHT treatment of murine 3T3-L1 or human SGBS adipocytes for 24 h significantly decreased the mRNA express... | https://www.wikidoc.org/index.php/STK11 | |
10583f6c328f243cb156b2774a597155f846d7eb | wikidoc | STK24 | STK24
Serine/threonine-protein kinase 24 is an enzyme that in humans is encoded by the STK24 gene located in the chromosome 13, band q32.2. It is also known as Mammalian STE20-like protein kinase 3 (MST-3). The protein is 443 amino acids long and its mass is 49 kDa.
# Classification and discovery
The yeast 'Sterile 2... | STK24
Serine/threonine-protein kinase 24 is an enzyme that in humans is encoded by the STK24 gene [1][2][3] located in the chromosome 13, band q32.2. It is also known as Mammalian STE20-like protein kinase 3 (MST-3).[4] The protein is 443 amino acids long and its mass is 49 kDa.[4]
# Classification and discovery
The ... | https://www.wikidoc.org/index.php/STK24 | |
f21b8420e120bb722cc1fa406799bb355576b1a8 | wikidoc | STK39 | STK39
STE20/SPS1-related proline-alanine-rich protein kinase is an enzyme that in humans is encoded by the STK39 gene.
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of s... | STK39
STE20/SPS1-related proline-alanine-rich protein kinase is an enzyme that in humans is encoded by the STK39 gene.[1][2]
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylati... | https://www.wikidoc.org/index.php/STK39 | |
9dd61b5e9ffe7ec993f086afebc240c56d744a81 | wikidoc | STUB1 | STUB1
STUB1 (STIP1 homology and U-Box containing protein 1) is a human gene that codes for the protein CHIP (C terminus of HSC70-Interacting Protein).
# Function
The CHIP protein encoded by this gene binds to and inhibits the ATPase activity of the chaperone proteins HSC70 and HSP70 and blocks the forward reaction of... | STUB1
STUB1 (STIP1 homology and U-Box containing protein 1) is a human gene that codes for the protein CHIP (C terminus of HSC70-Interacting Protein). [1][2]
# Function
The CHIP protein encoded by this gene binds to and inhibits the ATPase activity of the chaperone proteins HSC70 and HSP70 and blocks the forward reac... | https://www.wikidoc.org/index.php/STUB1 | |
e1d46079471c3ae506a2671d94bf08bd7883b8af | wikidoc | STX10 | STX10
Syntaxin-10 (STX10) is a SNARE protein that is encoded by the STX10 gene. This protein is found in most vertebrates (including humans) but is noticeably absent from mice. As with other SNARE proteins, STX10 facilitates vesicle fusion and thus is important for intracellular trafficking of proteins and other cel... | STX10
Syntaxin-10 (STX10) is a SNARE protein that is encoded by the STX10 gene.[1] This protein is found in most vertebrates (including humans) but is noticeably absent from mice.[2][3] As with other SNARE proteins, STX10 facilitates vesicle fusion and thus is important for intracellular trafficking of proteins and... | https://www.wikidoc.org/index.php/STX10 | |
e837180292c1aae06377489513f9b38e4afa20e2 | wikidoc | STX1A | STX1A
Syntaxin-1A is a protein that in humans is encoded by the STX1A gene.
# Function
Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic... | STX1A
Syntaxin-1A is a protein that in humans is encoded by the STX1A gene.[1]
# Function
Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presyna... | https://www.wikidoc.org/index.php/STX1A | |
eef0840b1dfce56333a9c954b0c3bd6289b86b8f | wikidoc | SUDS3 | SUDS3
Sin3 histone deacetylase corepressor complex component SDS3 is an enzyme that in humans is encoded by the SUDS3 gene.
# Function
SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003).
# Interactions
SUDS3 has been shown to ... | SUDS3
Sin3 histone deacetylase corepressor complex component SDS3 is an enzyme that in humans is encoded by the SUDS3 gene.[1][2]
# Function
SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003).[supplied by OMIM][2]
# Interacti... | https://www.wikidoc.org/index.php/SUDS3 | |
c3b3900507f828b16e53e641dd66b105dd2a839b | wikidoc | SUHW4 | SUHW4
Zinc finger protein 280D, also known as Suppressor Of Hairy Wing Homolog 4, SUWH4, Zinc Finger Protein 634, ZNF634, or KIAA1584, is a protein that in humans is encoded by the ZNF280D gene located on chromosome 15q21.3.
# Gene
There are a total of 24 possible exons in any variant of the ZNF280D gene. ZNF280D is ... | SUHW4
Zinc finger protein 280D, also known as Suppressor Of Hairy Wing Homolog 4, SUWH4, Zinc Finger Protein 634, ZNF634, or KIAA1584, is a protein that in humans is encoded by the ZNF280D gene located on chromosome 15q21.3.[1][2]
# Gene
There are a total of 24 possible exons in any variant of the ZNF280D gene.[3] Z... | https://www.wikidoc.org/index.php/SUHW4 | |
faa772e93ae077b6b48b85579b565b38776f10f0 | wikidoc | SULF1 | SULF1
Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.
Heparan sulfate proteoglycans (HSPGs) act as co-receptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endo-sulfatases, such as SULF1, selectively remov... | SULF1
Sulfatase 1, also known as SULF1, is an enzyme which in humans is encoded by the SULF1 gene.[1]
Heparan sulfate proteoglycans (HSPGs) act as co-receptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endo-sulfatases, such as SULF1, selectively r... | https://www.wikidoc.org/index.php/SULF1 | |
b0d7d7bba5680e3a6d0f29ba3ebd37cdbd0477c3 | wikidoc | SUMO3 | SUMO3
Small ubiquitin-related modifier 3 is a protein that in humans is encoded by the SUMO3 gene.
# Function
SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets protei... | SUMO3
Small ubiquitin-related modifier 3 is a protein that in humans is encoded by the SUMO3 gene.[1][2]
# Function
SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets... | https://www.wikidoc.org/index.php/SUMO3 | |
300c293aa5342e9a26b106d0b3a8a523628b0214 | wikidoc | SURF1 | SURF1
Surfeit locus protein 1 (SURF1) is a protein that in humans is encoded by the SURF1 gene. The protein encoded by SURF1 is a component of the mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex (MITRAC complex), which is involved in the regulation of cytochrome c oxidase asse... | SURF1
Surfeit locus protein 1 (SURF1) is a protein that in humans is encoded by the SURF1 gene.[1][2] The protein encoded by SURF1 is a component of the mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex (MITRAC complex), which is involved in the regulation of cytochrome c oxida... | https://www.wikidoc.org/index.php/SURF1 | |
c67ffe71cfab4bf90c41e1e2c3d751ecf32ef0cf | wikidoc | SUZ12 | SUZ12
Polycomb protein SUZ12 is a protein that in humans is encoded by the SUZ12 gene.
# Function
This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF... | SUZ12
Polycomb protein SUZ12 is a protein that in humans is encoded by the SUZ12 gene.[1][2][3][4]
# Function
This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this ... | https://www.wikidoc.org/index.php/SUZ12 | |
24b84bbc3fa45317b4f3f7a75d91d5e600befb8c | wikidoc | SYMPK | SYMPK
Symplekin is a protein that in humans is encoded by the SYMPK gene.
# Function
This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to... | SYMPK
Symplekin is a protein that in humans is encoded by the SYMPK gene.[1][2]
# Function
This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is tho... | https://www.wikidoc.org/index.php/SYMPK | |
910cc1ff4b03ef8cea640796adcfd6d3e19eae78 | wikidoc | SYT14 | SYT14
Synaptotagmin XIV is a protein that in humans is encoded by the SYT14 gene.
# Function
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmi... | SYT14
Synaptotagmin XIV is a protein that in humans is encoded by the SYT14 gene.[1]
# Function
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptot... | https://www.wikidoc.org/index.php/SYT14 | |
ffed306f9ad45f6d43ed6441f3d3b72ee218fd73 | wikidoc | SYTL1 | SYTL1
Synaptotagmin-like protein 1 is a protein that in humans is encoded by the SYTL1 gene.
# Model organisms
Model organisms have been used in the study of SYTL1 function. A conditional knockout mouse line, called Sytl1tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consortium program — a hi... | SYTL1
Synaptotagmin-like protein 1 is a protein that in humans is encoded by the SYTL1 gene.[1][2]
# Model organisms
Model organisms have been used in the study of SYTL1 function. A conditional knockout mouse line, called Sytl1tm1a(KOMP)Wtsi[11][12] was generated as part of the International Knockout Mouse Consortium... | https://www.wikidoc.org/index.php/SYTL1 | |
34ce48d3abbf80f4562ee20e20d1f02646dafcaa | wikidoc | Salix | Salix
Willows, sallows and osiers form the genus Salix, around 400 species of deciduous trees and shrubs, found primarily on moist soils in cold and temperate regions of the Northern Hemisphere. Most species are known as willow, but some narrow-leaved shrub species are called osier, and some broader-leaved species are... | Salix
Willows, sallows and osiers form the genus Salix, around 400 species[1] of deciduous trees and shrubs, found primarily on moist soils in cold and temperate regions of the Northern Hemisphere. Most species are known as willow, but some narrow-leaved shrub species are called osier, and some broader-leaved species... | https://www.wikidoc.org/index.php/Salix | |
0362de95bc5286930a4ee2756453e669a00d0387 | wikidoc | Sarin | Sarin
Sarin, also known by its NATO designation of GB, (O-Isopropyl methylphosphonofluoridate) is an extremely toxic substance whose sole application is as a nerve agent. As a chemical weapon, it is classified as a weapon of mass destruction by the United Nations in UN Resolution 687. Production and stockpiling of Sari... | Sarin
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Template:Chembox new
Sarin, also known by its NATO designation of GB, (O-Isopropyl methylphosphonofluoridate) is an extremely toxic substance whose sole application is as a nerve agent. As a chemical weapon, it is classified as a weapon of mass destruction by th... | https://www.wikidoc.org/index.php/Sarin | |
28903d1e9395fc40719be3d5838ff32f7dfde060 | wikidoc | Scalp | Scalp
# Overview
The scalp is the anatomical area bordered by the face anteriorly and the neck to the sides and posteriorly.
# Layers
It is usually described as having five layers, which can be remembered with the mnemonic "SCALP":
- S: The skin on the head from which head hair grows. It is richly supplied with blood... | Scalp
Template:Infobox Anatomy
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Overview
The scalp is the anatomical area bordered by the face anteriorly and the neck to the sides and posteriorly.
# Layers
It is usually described as having five layers, which can be remembered with the mnemonic "SCALP":[1]
- S: T... | https://www.wikidoc.org/index.php/Scalp | |
1c25f1b433ce8ff5cd60661d0a26fd17d2c2b0d8 | wikidoc | Semen | Semen
Semen is an organic fluid (also known as seminal fluid) that usually contains spermatozoa. It is secreted by the gonads (sexual glands) and other sexual organs of male or hermaphroditic animals for fertilization of female ova. The process of discharge is called ejaculation.
# Physiological aspects
## Internal a... | Semen
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]
Semen is an organic fluid (also known as seminal fluid) that usually contains spermatozoa. It is secreted by the gonads (sexual glands) and other sexual organs of male or hermaphroditic animals for fertilization of female ova. The process of discharge is called ... | https://www.wikidoc.org/index.php/Semen |
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