id stringlengths 40 40 | source stringclasses 9
values | title stringlengths 2 345 | clean_text stringlengths 35 1.63M | raw_text stringlengths 4 1.63M | url stringlengths 4 498 | overview stringlengths 0 10k |
|---|---|---|---|---|---|---|
08b386773b66d3df7c79ee8f4e7a60e833c18a39 | wikidoc | P2RY8 | P2RY8
P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.
# Function
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, ... | P2RY8
P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.[1][2]
# Function
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 ... | https://www.wikidoc.org/index.php/P2RY8 | |
a623e96bf5a1ce62e42b114117650db76bebdb56 | wikidoc | PA2G4 | PA2G4
Proliferation-associated protein 2G4 (PA2G4) also known as ErbB3-binding protein 1 (EBP1) is a protein that in humans is encoded by the PA2G4 gene.
# Function
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and m... | PA2G4
Proliferation-associated protein 2G4 (PA2G4) also known as ErbB3-binding protein 1 (EBP1) is a protein that in humans is encoded by the PA2G4 gene.[1]
# Function
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes a... | https://www.wikidoc.org/index.php/PA2G4 | |
6572f9588a911f98050ff274537951961ea1e642 | wikidoc | PAC-1 | PAC-1
# Overview
PAC-1 (first procaspase activating compound) is a synthesized chemical compound that selectively induces apoptosis, or cell suicide, in cancerous cells. PAC-1 has shown good results in mouse models and is being further evaluated for use in humans.
# Function and discovery
PAC-1 (pronounced "pack one... | PAC-1
# Overview
PAC-1 (first procaspase activating compound) is a synthesized chemical compound that selectively induces apoptosis, or cell suicide, in cancerous cells. PAC-1 has shown good results in mouse models and is being further evaluated for use in humans.
# Function and discovery
PAC-1 (pronounced "pack one... | https://www.wikidoc.org/index.php/PAC-1 | |
a9d493effd62b96fa9db9b03b433861b581ffab5 | wikidoc | PACS1 | PACS1
Phosphofurin acidic cluster sorting protein 1, also known as PACS-1, is a protein that in humans is encoded by the PACS1 gene.
# Function
The PACS-1 protein has a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homol... | PACS1
Phosphofurin acidic cluster sorting protein 1, also known as PACS-1, is a protein that in humans is encoded by the PACS1 gene.[1][2][3]
# Function
The PACS-1 protein has a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of... | https://www.wikidoc.org/index.php/PACS1 | |
f560899d86b3f4cbe251b248ee3d75cb4534e076 | wikidoc | PADI2 | PADI2
Protein-arginine deiminase type-2 is an enzyme that in humans is encoded by the PADI2 gene.
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ion... | PADI2
Protein-arginine deiminase type-2 is an enzyme that in humans is encoded by the PADI2 gene.[1][2]
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calc... | https://www.wikidoc.org/index.php/PADI2 | |
66e92febccdfd829f696cfd4584fcd2c1e0c8d2d | wikidoc | PADI4 | PADI4
Peptidyl arginine deiminase, type IV, also known as PADI4, is a human protein which in humans is encoded by the PADI4 gene.
# Molecular biology
The human gene is found on the short arm of Chromosome 1 near the telomere (1p36.13). It is located on the Watson (plus) strand and is 55,806 bases long. The protein is ... | PADI4
Peptidyl arginine deiminase, type IV, also known as PADI4, is a human protein which in humans is encoded by the PADI4 gene.[1][2]
# Molecular biology
The human gene is found on the short arm of Chromosome 1 near the telomere (1p36.13). It is located on the Watson (plus) strand and is 55,806 bases long. The prot... | https://www.wikidoc.org/index.php/PADI4 | |
27e69118e2f53b649a999fdc0b444f970ab15f21 | wikidoc | PALB2 | PALB2
Partner and localizer of BRCA2, also known as PALB2 or FANCN, is a protein which in humans is encoded by the PALB2 gene.
# Function
This gene encodes a protein that functions in genome maintenance (double strand break repair). This protein binds to and colocalizes with the breast cancer 2 early onset protein (BR... | PALB2
Partner and localizer of BRCA2, also known as PALB2 or FANCN, is a protein which in humans is encoded by the PALB2 gene.[1][2][3]
# Function
This gene encodes a protein that functions in genome maintenance (double strand break repair). This protein binds to and colocalizes with the breast cancer 2 early onset p... | https://www.wikidoc.org/index.php/PALB2 | |
28ffde0daabc03ba1a19f847ba4a1bd258ee0342 | wikidoc | PAM16 | PAM16
Mitochondrial import inner membrane translocase subunit TIM16 also known as presequence translocated-associated motor subunit PAM16, mitochondria-associated granulocyte macrophage CSF-signaling molecule, or presequence translocated-associated motor subunit PAM16 is a protein that in humans is encoded by the PAM16... | PAM16
Mitochondrial import inner membrane translocase subunit TIM16 also known as presequence translocated-associated motor subunit PAM16, mitochondria-associated granulocyte macrophage CSF-signaling molecule, or presequence translocated-associated motor subunit PAM16 is a protein that in humans is encoded by the PAM1... | https://www.wikidoc.org/index.php/PAM16 | |
29bfe18a32ae703d1f950d295877b28020a25a00 | wikidoc | PANX1 | PANX1
Pannexin 1 is a protein in humans that is encoded by the PANX1 gene.
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in vari... | PANX1
Pannexin 1 is a protein in humans that is encoded by the PANX1 gene.[1]
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in ... | https://www.wikidoc.org/index.php/PANX1 | |
3673527471c608900a0fd27f95eb98c749f4b480 | wikidoc | PARP1 | PARP1
Poly polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. It is one of the PARP family of enzymes.
# Function
PARP1 works:
- By modifying nuclear proteins by poly ADP-ribosylation.
- In conjunction with BRCA, which acts on... | PARP1
Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene.[1] It is one of the PARP family of enzymes.
# Function
PARP1 works:
- By modifying nuclear proteins by poly ADP-ribosylation.
- In conjunct... | https://www.wikidoc.org/index.php/PARP1 | |
a7098388f7286f8a479d59d00dfe8dce45c80ca2 | wikidoc | PARP2 | PARP2
Poly polymerase 2 is an enzyme that in humans is encoded by the PARP2 gene. It is one of the PARP family of enzymes.
# Function
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a cata... | PARP2
Poly [ADP-ribose] polymerase 2 is an enzyme that in humans is encoded by the PARP2 gene.[1][2][3] It is one of the PARP family of enzymes.
# Function
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. T... | https://www.wikidoc.org/index.php/PARP2 | |
83fbd7d09dc8734c70f2d2b12c7122c225eff78d | wikidoc | PBDC1 | PBDC1
CXorf26 (Chromosome X Open Reading Frame 26), also known as MGC874, is a well conserved human gene found on the plus strand of the short arm of the X chromosome. The exact function of the gene is poorly understood, but the polysaccharide biosynthesis domain that spans a major portion of the protein product (known... | PBDC1
CXorf26 (Chromosome X Open Reading Frame 26), also known as MGC874, is a well conserved human gene found on the plus strand of the short arm of the X chromosome. The exact function of the gene is poorly understood, but the polysaccharide biosynthesis domain that spans a major portion of the protein product (know... | https://www.wikidoc.org/index.php/PBDC1 | |
0a0e97df1456b7a47d208c5c70298585d03a9f8d | wikidoc | PBRM1 | PBRM1
Protein polybromo-1 (PB1) also known as BRG1-associated factor 180 (BAF180) is a protein that in humans is encoded by the PBRM1 gene.
# Structure and function
Component of the SWI/SNF-B (PBAF) chromatin-remodeling complex, which contains at least SMARCA4/BRG1, SMARCB1/SNF5/INI1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF... | PBRM1
Protein polybromo-1 (PB1) also known as BRG1-associated factor 180 (BAF180) is a protein that in humans is encoded by the PBRM1 gene.[1][2][3]
# Structure and function
Component of the SWI/SNF-B (PBAF) chromatin-remodeling complex, which contains at least SMARCA4/BRG1, SMARCB1/SNF5/INI1/BAF47, ACTL6A/BAF53A or ... | https://www.wikidoc.org/index.php/PBRM1 | |
33a54e48de1ac6dacae62eb12a061cb2e82b7be4 | wikidoc | PCBP2 | PCBP2
Poly(rC)-binding protein 2 is a protein that in humans is encoded by the PCBP2 gene.
# Function
The protein encoded by this gene appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. It contains three K-homologous (KH) domains which may be inv... | PCBP2
Poly(rC)-binding protein 2 is a protein that in humans is encoded by the PCBP2 gene.[1]
# Function
The protein encoded by this gene appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. It contains three K-homologous (KH) domains which may be... | https://www.wikidoc.org/index.php/PCBP2 | |
f71d7f8a4f770e00e673b70e9e8f9107ad15db18 | wikidoc | PCDHY | PCDHY
PCDH11Y is a gene unique to human males that encodes Protocadherin 11Y, a protein that guides the development of nerve cells. PCDH11X, located on the X chromosome, is common, in both sexes, to humans and our nearest relative, the chimpanzee; however, PCDH11Y, located on the Y chromosome, is unique to males.
In t... | PCDHY
PCDH11Y is a gene unique to human males that encodes Protocadherin 11Y, a protein that guides the development of nerve cells. PCDH11X, located on the X chromosome, is common, in both sexes, to humans and our nearest relative, the chimpanzee; however, PCDH11Y, located on the Y chromosome, is unique to males.[1]
... | https://www.wikidoc.org/index.php/PCDHY | |
f0be6ba2d696dae85e3f55fd2959bf059cc8ac0d | wikidoc | PCSK5 | PCSK5
Proprotein convertase subtilisin/kexin type 5 is an enzyme that in humans is encoded by the PCSK5 gene, found in chromosome 9q21.3 Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.
# Function
The protein encoded by this gene belongs to the subtilisi... | PCSK5
Proprotein convertase subtilisin/kexin type 5 is an enzyme that in humans is encoded by the PCSK5 gene, found in chromosome 9q21.3[1][2][3] Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.
# Function
The protein encoded by this gene belongs to the... | https://www.wikidoc.org/index.php/PCSK5 | |
522f20ed05b5429b0aa26c6b1d87fd08da2913e1 | wikidoc | PCSK6 | PCSK6
Proprotein convertase subtilisin/kexin type 6 is an enzyme that in humans is encoded by the PCSK6 gene. PCSK6 is a protease that cleaves NODAL into an active form to help trigger the development of left/right (LR) asymmetry. It may also be involved in left and right handedness in humans.
# Function
The protein e... | PCSK6
Proprotein convertase subtilisin/kexin type 6 is an enzyme that in humans is encoded by the PCSK6 gene.[1][2] PCSK6 is a protease that cleaves NODAL into an active form to help trigger the development of left/right (LR) asymmetry.[3] It may also be involved in left and right handedness in humans.[4][5][6]
# Fun... | https://www.wikidoc.org/index.php/PCSK6 | |
8c4cdcda0e541c2f00263aeb6d27d0d0034ed074 | wikidoc | PCSK9 | PCSK9
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein convertase family of proteins that activate other proteins. Similar genes (orthologs) are found across many species. As with many proteins, PCSK9 is inacti... | PCSK9
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1.[1] It is the 9th member of the proprotein convertase family of proteins that activate other proteins.[2] Similar genes (orthologs) are found across many species. As with many proteins, PCSK9 is... | https://www.wikidoc.org/index.php/PCSK9 | |
589fd97806a8edb9dfc28f0f469bc66f1f04254d | wikidoc | PD-L1 | PD-L1
Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.
Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the adapti... | PD-L1
Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.[1]
Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the ad... | https://www.wikidoc.org/index.php/PD-L1 | |
3b864699ec6a17862b016997fdbec674be68b83b | wikidoc | PDCD2 | PDCD2
Programmed cell death protein 2 is a protein that in humans is encoded by the PDCD2 gene.
# Function
This gene encodes a nuclear protein expressed in a variety of tissues. The rat homolog, Rp8, is transiently expressed in immature thymocytes and is thought to be involved in programmed cell death. Expression of t... | PDCD2
Programmed cell death protein 2 is a protein that in humans is encoded by the PDCD2 gene.[1][2]
# Function
This gene encodes a nuclear protein expressed in a variety of tissues. The rat homolog, Rp8, is transiently expressed in immature thymocytes and is thought to be involved in programmed cell death. Expressi... | https://www.wikidoc.org/index.php/PDCD2 | |
93e6cbe6d9b21f500b51fbbf09518a95742d6176 | wikidoc | PDCD4 | PDCD4
Programmed cell death protein 4 is a protein that in humans is encoded by the PDCD4 gene. It is one of the targets of an oncomiR, MIRN21.
# Function
This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The ge... | PDCD4
Programmed cell death protein 4 is a protein that in humans is encoded by the PDCD4 gene.[1][2] It is one of the targets of an oncomiR, MIRN21.[3]
# Function
This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cel... | https://www.wikidoc.org/index.php/PDCD4 | |
1ce5edd895f9935554dc5af3e8fcf2c98cbc8629 | wikidoc | PDCD6 | PDCD6
Programmed cell death protein 6 is a protein that in humans is encoded by the PDCD6 gene.
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This... | PDCD6
Programmed cell death protein 6 is a protein that in humans is encoded by the PDCD6 gene.[1]
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. ... | https://www.wikidoc.org/index.php/PDCD6 | |
53791c74c51b9d2a50a43670d0e841b6056f3340 | wikidoc | PDE4A | PDE4A
cAMP-specific 3',5'-cyclic phosphodiesterase 4A is an enzyme that in humans is encoded by the PDE4A gene.
# Function
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the secondary messenger, cAMP, which is a regulator and me... | PDE4A
cAMP-specific 3',5'-cyclic phosphodiesterase 4A is an enzyme that in humans is encoded by the PDE4A gene.[1][2]
# Function
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the secondary messenger, cAMP, which is a regulator... | https://www.wikidoc.org/index.php/PDE4A | |
c4ec28bfbec7889e4cddc8543731b6adbf0610fb | wikidoc | PDE4B | PDE4B
cAMP-specific 3',5'-cyclic phosphodiesterase 4B is an enzyme that in humans is encoded by the PDE4B gene.
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cel... | PDE4B
cAMP-specific 3',5'-cyclic phosphodiesterase 4B is an enzyme that in humans is encoded by the PDE4B gene.[1]
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of... | https://www.wikidoc.org/index.php/PDE4B | |
a825bfbb4fdb00a5437540f62e6561a59b6b04bd | wikidoc | PDE4D | PDE4D
cAMP-specific 3',5'-cyclic phosphodiesterase 4D is an enzyme that in humans is encoded by the PDE4D gene.
# Function
The PDE4D gene is complex and has at least 9 different isoforms that encode functional proteins. These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in mu... | PDE4D
cAMP-specific 3',5'-cyclic phosphodiesterase 4D is an enzyme that in humans is encoded by the PDE4D gene.
# Function
The PDE4D gene is complex and has at least 9 different isoforms that encode functional proteins. These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in m... | https://www.wikidoc.org/index.php/PDE4D | |
db651f501119de25f799e19cea0d69f036f14367 | wikidoc | PDE6B | PDE6B
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta is the beta subunit of the protein complex PDE6 that is encoded by the PDE6B gene. PDE6 is crucial in transmission and amplification of visual signal. The existence of this beta subunit is essential for normal PDE6 functioning. Mutations in this subuni... | PDE6B
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta is the beta subunit of the protein complex PDE6 that is encoded by the PDE6B gene.[1][2] PDE6 is crucial in transmission and amplification of visual signal. The existence of this beta subunit is essential for normal PDE6 functioning. Mutations in this... | https://www.wikidoc.org/index.php/PDE6B | |
1fb83f7124f847826dd7a270306d3e9e1d5388d4 | wikidoc | PDGFB | PDGFB
Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene.
# Function
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a... | PDGFB
Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene.[1][2]
# Function
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characteriz... | https://www.wikidoc.org/index.php/PDGFB | |
915984c65377701f1f561de7da469b2a27e01f02 | wikidoc | PDGFC | PDGFC
Platelet-derived growth factor C, also known as PDGF-C, is a 345-amino acid protein that in humans is encoded by the PDGFC gene. Platelet-derived growth factors are important in connective tissue growth, survival and function, and consist of disulphide-linked dimers involving two polypeptide chains, PDGF-A and PD... | PDGFC
Platelet-derived growth factor C, also known as PDGF-C, is a 345-amino acid protein that in humans is encoded by the PDGFC gene.[1][2] Platelet-derived growth factors are important in connective tissue growth, survival and function, and consist of disulphide-linked dimers involving two polypeptide chains, PDGF-A... | https://www.wikidoc.org/index.php/PDGFC | |
46d63084e228037a79f707b175ea268504dee26c | wikidoc | PDS5B | PDS5B
Sister chromatid cohesion protein PDS5 homolog B is a protein that in humans is encoded by the PDS5B gene.
# Model organisms
Model organisms have been used in the study of PDS5B function. A conditional knockout mouse line, called Pds5btm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Con... | PDS5B
Sister chromatid cohesion protein PDS5 homolog B is a protein that in humans is encoded by the PDS5B gene.[1][2][3]
# Model organisms
Model organisms have been used in the study of PDS5B function. A conditional knockout mouse line, called Pds5btm1a(EUCOMM)Wtsi[7][8] was generated as part of the International Kn... | https://www.wikidoc.org/index.php/PDS5B | |
e1c9c6e1973eab421fed6d7387f23149fb6a4c37 | wikidoc | PEG10 | PEG10
Retrotransposon-derived protein PEG10 is a protein that in humans is encoded by the PEG10 gene.
# Function
This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag protein... | PEG10
Retrotransposon-derived protein PEG10 is a protein that in humans is encoded by the PEG10 gene.[1][2][3][4]
# Function
This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic o... | https://www.wikidoc.org/index.php/PEG10 | |
855ec1329a582a54fb34f194f589715d6e09c044 | wikidoc | PEPAP | PEPAP
PEPAP is an opioid analgesic that is an analogue of pethidine (meperidine).
It is related to the drug MPPP, with a phenethyl group in place of the 1-methyl substitution and an acetate ester rather than propionate.
PEPAP presumably has similar effects to other opioids, producing analgesia, sedation and euphoria. S... | PEPAP
PEPAP is an opioid analgesic that is an analogue of pethidine (meperidine).
It is related to the drug MPPP, with a phenethyl group in place of the 1-methyl substitution and an acetate ester rather than propionate.
PEPAP presumably has similar effects to other opioids, producing analgesia, sedation and euphoria. ... | https://www.wikidoc.org/index.php/PEPAP | |
9ae6ef74b319e72db7521292a54c0ddf2118bdfc | wikidoc | PEX10 | PEX10
Peroxisome biogenesis factor 10 is a protein that in humans is encoded by the PEX10 gene. Alternative splicing results in two transcript variants encoding different isoforms.
# Function
Peroxisome biogenesis factor 10 is involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal... | PEX10
Peroxisome biogenesis factor 10 is a protein that in humans is encoded by the PEX10 gene.[1][2] Alternative splicing results in two transcript variants encoding different isoforms.
# Function
Peroxisome biogenesis factor 10 is involved in import of peroxisomal matrix proteins. This protein localizes to the pero... | https://www.wikidoc.org/index.php/PEX10 | |
47bd66388b8a061a8c6f6e51401c181e7273cb79 | wikidoc | PEX12 | PEX12
Peroxisome assembly protein 12 is a protein that in humans is encoded by the PEX12 gene.
# Function
PEX12 is needed for protein import into peroxisomes. This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes.
# Clinical significance... | PEX12
Peroxisome assembly protein 12 is a protein that in humans is encoded by the PEX12 gene.[1][2]
# Function
PEX12 is needed for protein import into peroxisomes.[3] This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes.
# Clinical si... | https://www.wikidoc.org/index.php/PEX12 | |
f258afa6bef32e0841adc279cb675d97657c5536 | wikidoc | PGAM2 | PGAM2
Phosphoglycerate mutase 2 (PGAM2), also known as muscle-specific phosphoglycerate mutase (PGAM-M), is a phosphoglycerate mutase that, in humans, is encoded by the PGAM2 gene on chromosome 7.
Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA... | PGAM2
Phosphoglycerate mutase 2 (PGAM2), also known as muscle-specific phosphoglycerate mutase (PGAM-M), is a phosphoglycerate mutase that, in humans, is encoded by the PGAM2 gene on chromosome 7.[1][2]
Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate... | https://www.wikidoc.org/index.php/PGAM2 | |
5f843bb6fde0e5bb5640c6d675af200e554bae0b | wikidoc | PHKG2 | PHKG2
Phosphorylase b kinase gamma catalytic chain, testis/liver isoform is an enzyme that in humans is encoded by the PHKG2 gene.
The PHKG2 gene provides instructions for making one piece, the gamma subunit, of the phosphorylase b kinase enzyme. This enzyme is made up of 16 subunits, four each of the alpha, beta, gamm... | PHKG2
Phosphorylase b kinase gamma catalytic chain, testis/liver isoform is an enzyme that in humans is encoded by the PHKG2 gene.[1][2][3]
The PHKG2 gene provides instructions for making one piece, the gamma subunit, of the phosphorylase b kinase enzyme. This enzyme is made up of 16 subunits, four each of the alpha, ... | https://www.wikidoc.org/index.php/PHKG2 | |
6a1f63864719009ea31ffbd717f549bdedf13bf4 | wikidoc | PHLPP | PHLPP
The PHLPP isoforms (PH domain and Leucine rich repeat Protein Phosphatases) are a pair of protein phosphatases, PHLPP1 and PHLPP2, that are important regulators of Akt serine-threonine kinases (Akt1, Akt2, Akt3) and conventional/novel protein kinase C (PKC) isoforms. PHLPP may act as a tumor suppressor in sev... | PHLPP
The PHLPP isoforms (PH domain and Leucine rich repeat Protein Phosphatases) are a pair of protein phosphatases, PHLPP1 and PHLPP2, that are important regulators of Akt serine-threonine kinases (Akt1, Akt2, Akt3) and conventional/novel protein kinase C (PKC) isoforms. PHLPP may act as a tumor suppressor in se... | https://www.wikidoc.org/index.php/PHLPP | |
3af41129951c7de976379258fe9db555e833d561 | wikidoc | PI4KA | PI4KA
Phosphatidylinositol 4-kinase alpha is an enzyme that in humans is encoded by the PI4KA gene.
# Function
This gene encodes a 1-phosphatidylinositol 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into ... | PI4KA
Phosphatidylinositol 4-kinase alpha is an enzyme that in humans is encoded by the PI4KA gene.[1][2][3]
# Function
This gene encodes a 1-phosphatidylinositol 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classi... | https://www.wikidoc.org/index.php/PI4KA | |
8aba1d57605c546b9f4fffb0326293dbc1118682 | wikidoc | PI4KB | PI4KB
Phosphatidylinositol 4-kinase beta is an enzyme that in humans is encoded by the PI4KB gene.
# Classification
This gene encodes a phosphatidylinositol 4-kinase which catalyzes phosphorylation of phosphatidylinositol at the D-4 position, yielding phosphatidylinositol 4-phosphate (PI4P). Besides the fact, that PI4... | PI4KB
Phosphatidylinositol 4-kinase beta is an enzyme that in humans is encoded by the PI4KB gene.[1][2][3]
# Classification
This gene encodes a phosphatidylinositol 4-kinase which catalyzes phosphorylation of phosphatidylinositol at the D-4 position, yielding phosphatidylinositol 4-phosphate (PI4P). Besides the fact... | https://www.wikidoc.org/index.php/PI4KB | |
7066101a720febaa2635d8b25737adb96f2da0ee | wikidoc | PIAS3 | PIAS3
E3 SUMO-protein ligase PIAS3 is an enzyme that in humans is encoded by the PIAS3 gene.
# PIAS family
The mammalian PIAS family consists of four members: PIAS1, PIAS2, PIAS3 and PIAS4. In Drosophila, a single PIAS homologue named dPIAS/Zimp has been identified. In yeast, two PIAS-related proteins were identified... | PIAS3
E3 SUMO-protein ligase PIAS3 is an enzyme that in humans is encoded by the PIAS3 gene.[1][2]
# PIAS family
The mammalian PIAS family consists of four members: PIAS1, PIAS2, PIAS3 and PIAS4. In Drosophila, a single PIAS homologue named dPIAS/Zimp has been identified.[3] In yeast, two PIAS-related proteins were ... | https://www.wikidoc.org/index.php/PIAS3 | |
64af8096dd3552e14a37a83eb312be0dc6421d05 | wikidoc | PILRA | PILRA
Paired immunoglobin like type 2 receptor alpha is a protein that in humans is encoded by the PILRA gene.
# Function
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of seve... | PILRA
Paired immunoglobin like type 2 receptor alpha is a protein that in humans is encoded by the PILRA gene.
[1]
# Function
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of... | https://www.wikidoc.org/index.php/PILRA | |
1c97bdb900f238453965e6227b57e8f3dc1fa218 | wikidoc | PINK1 | PINK1
PTEN-induced kinase 1 (PINK1) is a mitochondrial serine/threonine-protein kinase encoded by the PINK1 gene.
It is thought to protect cells from stress-induced mitochondrial dysfunction. PINK1 activity causes the parkin protein to bind to depolarized mitochondria to induce autophagy of those mitochondria. PINK1 i... | PINK1
PTEN-induced kinase 1 (PINK1) is a mitochondrial serine/threonine-protein kinase encoded by the PINK1 gene.[1][2]
It is thought to protect cells from stress-induced mitochondrial dysfunction. PINK1 activity causes the parkin protein to bind to depolarized mitochondria to induce autophagy of those mitochondria.[3... | https://www.wikidoc.org/index.php/PINK1 | |
db9ce884749de0631a920bc5cad1f9d1738df4b1 | wikidoc | PINX1 | PINX1
PIN2/TERF1-interacting telomerase inhibitor 1, also known as PINX1, is a human gene. PINX1 is also known as PIN2 interacting protein 1. PINX1 is a telomerase inhibitor and a possible tumor suppressor.
# Interactions
PINX1 has been shown to interact with MCRS1, TERF1 and telomerase reverse transcriptase.
# Struc... | PINX1
PIN2/TERF1-interacting telomerase inhibitor 1, also known as PINX1, is a human gene.[1] PINX1 is also known as PIN2 interacting protein 1.[2] PINX1 is a telomerase inhibitor and a possible tumor suppressor.
# Interactions
PINX1 has been shown to interact with MCRS1,[3] TERF1[4] and telomerase reverse transcript... | https://www.wikidoc.org/index.php/PINX1 | |
2274e9ad97646be82206f3b2341334836eb3b729 | wikidoc | PITX1 | PITX1
paired-like homeodomain 1 is a protein that in humans is encoded by the PITX1 gene.
# Function
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as... | PITX1
paired-like homeodomain 1 is a protein that in humans is encoded by the PITX1 gene.[1][2][3]
# Function
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This prote... | https://www.wikidoc.org/index.php/PITX1 | |
08e38b8c6e0ec642bdd86c0ddb86397f2f7bc505 | wikidoc | PITX2 | PITX2
Paired-like homeodomain transcription factor 2 also known as pituitary homeobox 2 is a protein that in humans is encoded by the PITX2 gene.
# Function
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor an... | PITX2
Paired-like homeodomain transcription factor 2 also known as pituitary homeobox 2 is a protein that in humans is encoded by the PITX2 gene.[1][2][3]
# Function
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription... | https://www.wikidoc.org/index.php/PITX2 | |
aa8b10997142997ee985d450d6ed61428b3e31d5 | wikidoc | PITX3 | PITX3
Pituitary homeobox 3 is a protein that in humans is encoded by the PITX3 gene.
# Function
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye d... | PITX3
Pituitary homeobox 3 is a protein that in humans is encoded by the PITX3 gene.[1][2]
# Function
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation durin... | https://www.wikidoc.org/index.php/PITX3 | |
013f1a7fda6321e397ed8979921b862be2372748 | wikidoc | PLCB1 | PLCB1
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 is an enzyme that in humans is encoded by the PLCB1 gene.
# Function
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium ... | PLCB1
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 is an enzyme that in humans is encoded by the PLCB1 gene.[1][2][3]
# Function
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction use... | https://www.wikidoc.org/index.php/PLCB1 | |
11b24f99273e9921a2422c1c36cd7e9aed1e1e46 | wikidoc | PLCB3 | PLCB3
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 is an enzyme that in humans is encoded by the PLCB3 gene.
The gene codes for the enzyme phospholipase C β3. The enzyme catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reacti... | PLCB3
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 is an enzyme that in humans is encoded by the PLCB3 gene.[1][2]
The gene codes for the enzyme phospholipase C β3. The enzyme catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This... | https://www.wikidoc.org/index.php/PLCB3 | |
db20a4853b42fabfe18d98eae7dbec2b91c67ad0 | wikidoc | PLCE1 | PLCE1
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1) is an enzyme that in humans is encoded by the PLCE1 gene. This gene encodes a phospholipase enzyme (PLCE1) that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphospha... | PLCE1
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1) is an enzyme that in humans is encoded by the PLCE1 gene.[1][2] This gene encodes a phospholipase enzyme (PLCE1) that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-tri... | https://www.wikidoc.org/index.php/PLCE1 | |
d8879b0359c0ffb8588bebc2ebecc1bbdeb0fbac | wikidoc | PLCG1 | PLCG1
Phospholipase C, gamma 1, also known as PLCG1, is a protein that in humans is encoded by the PLCG1 gene.
# Function
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and ... | PLCG1
Phospholipase C, gamma 1, also known as PLCG1, is a protein that in humans is encoded by the PLCG1 gene.[1][2]
# Function
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofact... | https://www.wikidoc.org/index.php/PLCG1 | |
9023df83473aface8e9e78f772573bdd914819c1 | wikidoc | PMPCA | PMPCA
Mitochondrial-processing peptidase subunit alpha is an enzyme that in humans is encoded by the PMPCA gene. This gene PMPCA encoded a protein that is a member of the peptidase M16 family. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins new... | PMPCA
Mitochondrial-processing peptidase subunit alpha is an enzyme that in humans is encoded by the PMPCA gene.[1][2][3] This gene PMPCA encoded a protein that is a member of the peptidase M16 family. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor pr... | https://www.wikidoc.org/index.php/PMPCA | |
cb354a945f45badddba4fe2c5546692ce2feaadd | wikidoc | PMPCB | PMPCB
Mitochondrial-processing peptidase subunit beta is an enzyme that in humans is encoded by the PMPCB gene. This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of prec... | PMPCB
Mitochondrial-processing peptidase subunit beta is an enzyme that in humans is encoded by the PMPCB gene.[1][2] This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides ... | https://www.wikidoc.org/index.php/PMPCB | |
50b004cd0cafddf77183afe990e391bbdf44c817 | wikidoc | PODXL | PODXL
Podocalyxin-like protein 1 is a protein that in humans is encoded by the PODXL gene.
# Function
This gene encodes a member of the CD34 sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Inactivation of the encoding gene in mice leads to anu... | PODXL
Podocalyxin-like protein 1 is a protein that in humans is encoded by the PODXL gene.[1]
# Function
This gene encodes a member of the CD34 sialomucin protein family.[2] The encoded protein was originally identified as an important component of glomerular podocytes. Inactivation of the encoding gene in mice leads... | https://www.wikidoc.org/index.php/PODXL | |
a6933fb846b4204b6bbc0b67f559e8a90859b91a | wikidoc | POLD1 | POLD1
The gene polymerase delta 1 (POLD1) encodes the large, POLD1/p125, catalytic subunit of the DNA polymerase delta (Polδ) complex. The Polδ enzyme is responsible for synthesizing the lagging strand of DNA, and has also been implicated in some activities at the leading strand (Figure 1). The POLD1/p125 subunit encod... | POLD1
The gene polymerase delta 1 (POLD1) encodes the large, POLD1/p125, catalytic subunit of the DNA polymerase delta (Polδ) complex.[1][2] The Polδ enzyme is responsible for synthesizing the lagging strand of DNA, and has also been implicated in some activities at the leading strand (Figure 1). The POLD1/p125 subuni... | https://www.wikidoc.org/index.php/POLD1 | |
b1975d262036657b54f8a676a452ea326957e5ff | wikidoc | POLG2 | POLG2
DNA polymerase subunit gamma-2, mitochondrial is a protein that in humans is encoded by the POLG2 gene. The POLG2 gene encodes a 55 kDa accessory subunit protein that imparts high processivity and salt tolerance to the catalytic subunit of DNA polymerase gamma, encoded by the POLG gene. Mutations in this gene re... | POLG2
DNA polymerase subunit gamma-2, mitochondrial is a protein that in humans is encoded by the POLG2 gene. The POLG2 gene encodes a 55 kDa accessory subunit protein that imparts high processivity and salt tolerance to the catalytic subunit of DNA polymerase gamma, encoded by the POLG gene.[1][2] Mutations in this ... | https://www.wikidoc.org/index.php/POLG2 | |
72c567074dd42c0b44975f38e5b2dfaa9cfebae9 | wikidoc | PORCN | PORCN
PORCN (porcupine homolog – Drosophila) is a human gene.
The protein is homologous to other membrane-bound O-acyltransferases.
# Function
The protein encoded by this gene is an endoplasmic reticulum transmembrane protein involved in processing of wingless proteins such as WNT7A.
# Clinical significance
Mutations... | PORCN
PORCN (porcupine homolog – Drosophila) is a human gene.[1][2]
The protein is homologous to other membrane-bound O-acyltransferases.
# Function
The protein encoded by this gene is an endoplasmic reticulum transmembrane protein involved in processing of wingless proteins such as WNT7A.[2]
# Clinical significance... | https://www.wikidoc.org/index.php/PORCN | |
869bf64f8683e1dbfd901e2e937f0718cb5ca50e | wikidoc | POTEB | POTEB
POTE ankyrin domain family, member B is a protein in humans that is encoded by the POTEB gene..It is most likely involved in mediating protein-protein interaction via its 5 ankyrin domains. POTEB is most probably aids in intracellular signaling, but is not likely to be a secreted or nuclear protein. POTEB's funct... | POTEB
POTE ankyrin domain family, member B is a protein in humans that is encoded by the POTEB gene.[1](Prostate, Ovary, Testes Expressed ankyrin domain family member B).It is most likely involved in mediating protein-protein interaction via its 5 ankyrin domains.[2] POTEB is most probably aids in intracellular signal... | https://www.wikidoc.org/index.php/POTEB | |
c21f588cb8f2481c22ca730028f147cc337e57c5 | wikidoc | PPIL3 | PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3 is an enzyme that in humans is encoded by the PPIL3 gene.
# Function
This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalyst... | PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3 is an enzyme that in humans is encoded by the PPIL3 gene.[1][2]
# Function
This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as c... | https://www.wikidoc.org/index.php/PPIL3 | |
b0a0c30d146e135a44c827d2d48acbb452a2e35f | wikidoc | PPM1A | PPM1A
Protein phosphatase 1A is an enzyme that in humans is encoded by the PPM1A gene.
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negativ... | PPM1A
Protein phosphatase 1A is an enzyme that in humans is encoded by the PPM1A gene.[1][2]
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and ... | https://www.wikidoc.org/index.php/PPM1A | |
4eac3883d1eb21dcee0da6263ac8ebce9f87a102 | wikidoc | PPP5C | PPP5C
Serine/threonine-protein phosphatase 5 is an enzyme that in humans is encoded by the PPP5C gene.
# Model organisms
Model organisms have been used in the study of PPP5C function. A conditional knockout mouse line, called Ppp5ctm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consortium pr... | PPP5C
Serine/threonine-protein phosphatase 5 is an enzyme that in humans is encoded by the PPP5C gene.[1][2]
# Model organisms
Model organisms have been used in the study of PPP5C function. A conditional knockout mouse line, called Ppp5ctm1a(EUCOMM)Wtsi[12][13] was generated as part of the International Knockout Mous... | https://www.wikidoc.org/index.php/PPP5C | |
52a0826fd9499dbd9868a085eca1a802d60ec4a2 | wikidoc | PQBP1 | PQBP1
Polyglutamine-binding protein 1 is a protein that in humans is encoded by the PQBP1 gene.
Polyglutamine binding protein-1 is a highly conserved nuclear protein expressed in mesodermal and nuclear tissues. The molecular roles of PQBP1 in embryonic development are still being understood, but it has been found to fu... | PQBP1
Polyglutamine-binding protein 1 is a protein that in humans is encoded by the PQBP1 gene.[1][2][3]
Polyglutamine binding protein-1 is a highly conserved nuclear protein expressed in mesodermal and nuclear tissues.[4] The molecular roles of PQBP1 in embryonic development are still being understood, but it has bee... | https://www.wikidoc.org/index.php/PQBP1 | |
0d94b96cfd66b1d343b13637813ad8f67c13ca19 | wikidoc | PRAME | PRAME
Melanoma antigen preferentially expressed in tumors is a protein that in humans is encoded by the PRAME gene.
# Function
This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This ex... | PRAME
Melanoma antigen preferentially expressed in tumors is a protein that in humans is encoded by the PRAME gene.[1][2][3]
# Function
This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testi... | https://www.wikidoc.org/index.php/PRAME | |
74a0e7f136ba44baef0be3d65057dfafcfda2c20 | wikidoc | PRDM1 | PRDM1
PR domain zinc finger protein 1 also known as BLIMP-1 is a protein that in humans is encoded by the PRDM1 gene. BLIMP-1 acts as a repressor of beta-interferon (β-IFN) gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the β-IFN gene promoter. Transcription of thi... | PRDM1
PR domain zinc finger protein 1 also known as BLIMP-1 is a protein that in humans is encoded by the PRDM1 gene.[1][2] BLIMP-1 acts as a repressor of beta-interferon (β-IFN) gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the β-IFN gene promoter. Transcription... | https://www.wikidoc.org/index.php/PRDM1 | |
d26fd9c090594febebd793ec027db205594700ea | wikidoc | PRDM2 | PRDM2
PR domain zinc finger protein 2 is a protein that in humans is encoded by the PRDM2 gene.
# Function
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsi... | PRDM2
PR domain zinc finger protein 2 is a protein that in humans is encoded by the PRDM2 gene.[1][2]
# Function
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-r... | https://www.wikidoc.org/index.php/PRDM2 | |
4d46c8f3acde837346f255df7e1f1893fef90f4d | wikidoc | PRDM9 | PRDM9
PR domain zinc finger protein 9 is a protein that in humans is encoded by the Prdm9 gene. PRDM9 is responsible for positioning recombination hotspots during meiosis by binding a DNA sequence motif encoded in its zinc finger domain. PRDM9 is the only speciation gene found so far in mammals, and is one of the faste... | PRDM9
PR domain[note 1] zinc finger protein 9 is a protein that in humans is encoded by the Prdm9 gene.[1] PRDM9 is responsible for positioning recombination hotspots during meiosis by binding a DNA sequence motif encoded in its zinc finger domain.[2] PRDM9 is the only speciation gene found so far in mammals, and is o... | https://www.wikidoc.org/index.php/PRDM9 | |
da0e726050c8df0a759d20822402c82e22722db2 | wikidoc | PRDX3 | PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene. It is a member of the peroxiredoxin family of antioxidant enzymes.
# Function
This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant ... | PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene.[1][2][3] It is a member of the peroxiredoxin family of antioxidant enzymes.
# Function
This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows si... | https://www.wikidoc.org/index.php/PRDX3 | |
8396dc44c4ef21cf3d555dff877f6d0644989489 | wikidoc | PRDX5 | PRDX5
Peroxiredoxin-5 (PRDX5), mitochondrial is a protein that in humans is encoded by the PRDX5 gene, located on chromosome 11.
This gene encodes a member of the six-member peroxiredoxin family of antioxidant enzymes. Like the other five members, PRDX5 is widely expressed in tissues but differs by its large subcellula... | PRDX5
Peroxiredoxin-5 (PRDX5), mitochondrial is a protein that in humans is encoded by the PRDX5 gene, located on chromosome 11.[1]
This gene encodes a member of the six-member peroxiredoxin family of antioxidant enzymes. Like the other five members, PRDX5 is widely expressed in tissues but differs by its large subcel... | https://www.wikidoc.org/index.php/PRDX5 | |
ff0150548cfc33322002ca4de95acb7e047b4b7a | wikidoc | PRDX6 | PRDX6
Peroxiredoxin-6 is a protein that in humans is encoded by the PRDX6 gene. It is a member of the peroxiredoxin family of antioxidant enzymes.
# Function
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sit... | PRDX6
Peroxiredoxin-6 is a protein that in humans is encoded by the PRDX6 gene.[1][2] It is a member of the peroxiredoxin family of antioxidant enzymes.
# Function
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct act... | https://www.wikidoc.org/index.php/PRDX6 | |
742d31e71650e1f3202cb0c170398f619d57f68b | wikidoc | PREX1 | PREX1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein is a protein that in humans is encoded by the PREX1 gene.
# Function
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and ... | PREX1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein is a protein that in humans is encoded by the PREX1 gene.[1][2][3][4]
# Function
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to... | https://www.wikidoc.org/index.php/PREX1 | |
f5caf7495db583fd96e99f1fc74fa7be48a27d27 | wikidoc | PRKCE | PRKCE
Protein kinase C epsilon type (PKCε) is an enzyme that in humans is encoded by the PRKCE gene. PKCε is an isoform of the large PKC family of protein kinases that play many roles in different tissues. In cardiac muscle cells, PKCε regulates muscle contraction through its actions at sarcomeric proteins, and PKCε mo... | PRKCE
Protein kinase C epsilon type (PKCε) is an enzyme that in humans is encoded by the PRKCE gene.[1][2] PKCε is an isoform of the large PKC family of protein kinases that play many roles in different tissues. In cardiac muscle cells, PKCε regulates muscle contraction through its actions at sarcomeric proteins, and ... | https://www.wikidoc.org/index.php/PRKCE | |
c1405c81be575e0a43151ac4749c40a7c93a5dd9 | wikidoc | PRKCQ | PRKCQ
Protein kinase C theta (PKC-θ) is an enzyme that in humans is encoded by the PRKCQ gene. PKC-θ, a member of serine/threonine kinases, is mainly expressed in hematopoietic cells with high levels in platelets and T lymphocytes, where plays a role in signal transduction. Different subpopulations of T cells vary in t... | PRKCQ
Protein kinase C theta (PKC-θ) is an enzyme that in humans is encoded by the PRKCQ gene.[1] PKC-θ, a member of serine/threonine kinases, is mainly expressed in hematopoietic cells[1] with high levels in platelets and T lymphocytes, where plays a role in signal transduction. Different subpopulations of T cells va... | https://www.wikidoc.org/index.php/PRKCQ | |
7d28e9a6cee04706f02414268bd79ba50ddbfc05 | wikidoc | PRMT1 | PRMT1
Protein arginine N-methyltransferase 1 is an enzyme that in humans is encoded by the PRMT1 gene.
# Function
The HRMT1L2 gene encodes a protein arginine methyltransferase that functions as a histone methyltransferase specific for histone H4.
# Model organisms
Model organisms have been used in the study of PRMT1 ... | PRMT1
Protein arginine N-methyltransferase 1 is an enzyme that in humans is encoded by the PRMT1 gene.[1]
# Function
The HRMT1L2 gene encodes a protein arginine methyltransferase that functions as a histone methyltransferase specific for histone H4.[2]
# Model organisms
Model organisms have been used in the study of... | https://www.wikidoc.org/index.php/PRMT1 | |
db8d3a925b44204defc83a60619b13afdca7096d | wikidoc | PRMT3 | PRMT3
Protein arginine N-methyltransferase 3 is an enzyme that in humans is encoded by the PRMT3 gene.
# Model organisms
Model organisms have been used in the study of PRMT3 function. A conditional knockout mouse line, called Prmt3tm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consortium pr... | PRMT3
Protein arginine N-methyltransferase 3 is an enzyme that in humans is encoded by the PRMT3 gene.[1][2]
# Model organisms
Model organisms have been used in the study of PRMT3 function. A conditional knockout mouse line, called Prmt3tm1a(EUCOMM)Wtsi[11][12] was generated as part of the International Knockout Mous... | https://www.wikidoc.org/index.php/PRMT3 | |
d05b8edcdc94a453833da723b44c0c5bb4b486ea | wikidoc | PROX1 | PROX1
Prospero homeobox protein 1 is a protein that in humans is encoded by the PROX1 gene.
# Interactions
PROX1 has been shown to interact with EP300.
# Production
PROX1 is produced primarily in the dentate gyrus in the mouse, and in the dentate gyrus and white matter in humans. Gene expression data for mouse, human... | PROX1
Prospero homeobox protein 1 is a protein that in humans is encoded by the PROX1 gene.[1][2]
# Interactions
PROX1 has been shown to interact with EP300.[3]
# Production
PROX1 is produced primarily in the dentate gyrus in the mouse, and in the dentate gyrus and white matter in humans. Gene expression data for mo... | https://www.wikidoc.org/index.php/PROX1 | |
0b080f239da34873ecd53810f60392b41966cb7a | wikidoc | PRPF6 | PRPF6
Pre-mRNA-processing factor 6 is a protein that in humans is encoded by the PRPF6 gene.
The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor... | PRPF6
Pre-mRNA-processing factor 6 is a protein that in humans is encoded by the PRPF6 gene.[1][2][3]
The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androge... | https://www.wikidoc.org/index.php/PRPF6 | |
cb14ad7c0524ff7dc748a7c1ce57f3d521328045 | wikidoc | PRR29 | PRR29
PRR29 is a protein located on human chromosome 17 that in humans is encoded by the PRR29 gene.
It is also commonly known as C17orf72. The gene has a size of 5961 base pairs and contains five exons.
# Gene
PRR29 is located on the long arm of chromosome 17 (17q23.3), starting at 63998344 and ending at 64004305. Th... | PRR29
PRR29 is a protein located on human chromosome 17 that in humans is encoded by the PRR29 gene.[1][2]
It is also commonly known as C17orf72. The gene has a size of 5961 base pairs and contains five exons.[1]
# Gene
PRR29 is located on the long arm of chromosome 17 (17q23.3), starting at 63998344 and ending at 64... | https://www.wikidoc.org/index.php/PRR29 | |
e59f3db4a37847d61f11ea550d8c0b2d29035c7b | wikidoc | PRR32 | PRR32
PRR32 is a protein that in humans is encoded by the CXorf64 (Chromosome X Open Reading Frame 64) gene. It was also found that the homologs of the PRR32 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat. It was also found through ncbi that 82 organisms have orthologs with human gene PRR323.
... | PRR32
PRR32 is a protein that in humans is encoded by the CXorf64 (Chromosome X Open Reading Frame 64) gene. It was also found that the homologs of the PRR32 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat. It was also found through ncbi that 82 organisms have orthologs with human gene PRR323.... | https://www.wikidoc.org/index.php/PRR32 | |
436f55a59859c8d570a77ce2520394592b92c6a9 | wikidoc | PRRT2 | PRRT2
Proline-rich transmembrane protein 2 is a protein that in humans is encoded by the PRRT2 gene.
# Structure and tissue distribution
This gene encodes a transmembrane protein containing a proline-rich domain in its N-terminal half. Studies in mice suggest that it is predominantly expressed in brain and spinal cord... | PRRT2
Proline-rich transmembrane protein 2 is a protein that in humans is encoded by the PRRT2 gene.[1]
# Structure and tissue distribution
This gene encodes a transmembrane protein containing a proline-rich domain in its N-terminal half. Studies in mice suggest that it is predominantly expressed in brain and spinal ... | https://www.wikidoc.org/index.php/PRRT2 | |
85ee91c86e6979bbb00fcf3905795a42331dd8e7 | wikidoc | PRRX1 | PRRX1
Paired related homeobox 1 is a protein that in humans is encoded by the PRRX1 gene.
# Function
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription coactivator, enhancing the DNA-binding activity o... | PRRX1
Paired related homeobox 1 is a protein that in humans is encoded by the PRRX1 gene.[1][2]
# Function
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription coactivator, enhancing the DNA-binding act... | https://www.wikidoc.org/index.php/PRRX1 | |
bae1f25d115c71ea8470c24ae61b5e202692699e | wikidoc | PRSS8 | PRSS8
Prostasin is a protein that in humans is encoded by the PRSS8 gene.
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to pro... | PRSS8
Prostasin is a protein that in humans is encoded by the PRSS8 gene.[1][2][3]
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is clea... | https://www.wikidoc.org/index.php/PRSS8 | |
2ad2c8fd4a8aa430a7b9e5c0ef409faea790aab2 | wikidoc | PSAT1 | PSAT1
Phosphoserine aminotransferase (PSA) also known as phosphohydroxythreonine aminotransferase (PSAT) is an enzyme that in humans is encoded by the PSAT1 gene.
The protein encoded by this gene is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila. Alternative sp... | PSAT1
Phosphoserine aminotransferase (PSA) also known as phosphohydroxythreonine aminotransferase (PSAT) is an enzyme that in humans is encoded by the PSAT1 gene.[1]
The protein encoded by this gene is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila. Alternativ... | https://www.wikidoc.org/index.php/PSAT1 | |
847773418084bf652b2e3084ae21388c0ad98532 | wikidoc | PSIP1 | PSIP1
PC4 and SFRS1 interacting protein 1, also known as lens epithelium-derived growth factor (LEDGF/p75), dense fine speckles 70kD protein (DFS 70) or transcriptional coactivator p75/p52, is a protein that in humans is encoded by the PSIP1 gene.
# Function
PSIP1 has not been clearly linked to a specific cellular mec... | PSIP1
PC4 and SFRS1 interacting protein 1, also known as lens epithelium-derived growth factor (LEDGF/p75), dense fine speckles 70kD protein (DFS 70) or transcriptional coactivator p75/p52, is a protein that in humans is encoded by the PSIP1 gene.[1][2]
# Function
PSIP1 has not been clearly linked to a specific cellu... | https://www.wikidoc.org/index.php/PSIP1 | |
435b8d834207e05c54ee4980879c21b1fc58c668 | wikidoc | PSMA2 | PSMA2
Proteasome subunit alpha type-2 is a protein that in humans is encoded by the PSMA2 gene. This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to the complete assembly of 20S proteasome compl... | PSMA2
Proteasome subunit alpha type-2 is a protein that in humans is encoded by the PSMA2 gene.[1][2][3] This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to the complete assembly of 20S protea... | https://www.wikidoc.org/index.php/PSMA2 | |
17b909d41d171f1fbc4e313a54b8e3521a97be64 | wikidoc | PSMA3 | PSMA3
Proteasome subunit alpha type-3 also known as macropain subunit C8 and proteasome component C8 is a protein that in humans is encoded by the PSMA3 gene. This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) th... | PSMA3
Proteasome subunit alpha type-3 also known as macropain subunit C8 and proteasome component C8 is a protein that in humans is encoded by the PSMA3 gene.[1][2] This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, bet... | https://www.wikidoc.org/index.php/PSMA3 | |
4ce100c7cfc571b7f1f1d81fce333a8dd6936826 | wikidoc | PSMA4 | PSMA4
Proteasome subunit alpha type-4 also known as macropain subunit C9, proteasome component C9, and 20S proteasome subunit alpha-3 is a protein that in humans is encoded by the PSMA4 gene. This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits inc... | PSMA4
Proteasome subunit alpha type-4 also known as macropain subunit C9, proteasome component C9, and 20S proteasome subunit alpha-3 is a protein that in humans is encoded by the PSMA4 gene.[1] This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits... | https://www.wikidoc.org/index.php/PSMA4 | |
d990ab8e7fcff2aa7ff0b9bf5df7bc9740a71551 | wikidoc | PSMA5 | PSMA5
Proteasome subunit alpha type-5 also known as 20S proteasome subunit alpha-5 is a protein that in humans is encoded by the PSMA5 gene. This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to ... | PSMA5
Proteasome subunit alpha type-5 also known as 20S proteasome subunit alpha-5 is a protein that in humans is encoded by the PSMA5 gene.[1][2] This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contribu... | https://www.wikidoc.org/index.php/PSMA5 | |
86eb487ea963d28d970aad56e09c979173d32154 | wikidoc | PSMA7 | PSMA7
Proteasome subunit alpha type-7 also known as 20S proteasome subunit alpha-4 is a protein that in humans is encoded by the PSMA7 gene. This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to... | PSMA7
Proteasome subunit alpha type-7 also known as 20S proteasome subunit alpha-4 is a protein that in humans is encoded by the PSMA7 gene.[1][2] This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contrib... | https://www.wikidoc.org/index.php/PSMA7 | |
8b063a5e4d80dc7a7f3f5e25df8fc20948738c7c | wikidoc | PSMB1 | PSMB1
Proteasome subunit beta type-1 also known as 20S proteasome subunit beta-6 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB1 gene. This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, bet... | PSMB1
Proteasome subunit beta type-1 also known as 20S proteasome subunit beta-6 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB1 gene.[1] This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i,... | https://www.wikidoc.org/index.php/PSMB1 | |
5798d0ca3a72df113707ee88001635e0e2a55e5a | wikidoc | PSMB2 | PSMB2
Proteasome subunit beta type-2 also known as 20S proteasome subunit beta-4 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB2 gene. This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, bet... | PSMB2
Proteasome subunit beta type-2 also known as 20S proteasome subunit beta-4 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB2 gene.[1] This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i,... | https://www.wikidoc.org/index.php/PSMB2 | |
233983ef3a4c3561857bbdc5843afdd86f605c0b | wikidoc | PSMB3 | PSMB3
Proteasome subunit beta type-3, also known as 20S proteasome subunit beta-3, is a protein that in humans is encoded by the PSMB3 gene. This protein is one of the 17 essential subunits that contribute to the complete assembly of the 20S proteasome complex. In particular, proteasome subunit beta type-2, along with ... | PSMB3
Proteasome subunit beta type-3, also known as 20S proteasome subunit beta-3, is a protein that in humans is encoded by the PSMB3 gene.[1] This protein is one of the 17 essential subunits[2] that contribute to the complete assembly of the 20S proteasome complex. In particular, proteasome subunit beta type-2, alon... | https://www.wikidoc.org/index.php/PSMB3 | |
47b73ad6c5d19ac1f3b07ff407f87c571375b582 | wikidoc | PSMB4 | PSMB4
Proteasome subunit beta type-4 also known as 20S proteasome subunit beta-7 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB4 gene.
This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, bet... | PSMB4
Proteasome subunit beta type-4 also known as 20S proteasome subunit beta-7 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB4 gene.[1]
This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i,... | https://www.wikidoc.org/index.php/PSMB4 | |
bd20a926c46bfe3b44078a264b0e347636a028a5 | wikidoc | PSMB5 | PSMB5
Proteasome subunit beta type-5 as known as 20S proteasome subunit beta-5 is a protein that in humans is encoded by the PSMB5 gene. This protein is one of the 17 essential subunits (alpha subunits 1–7, constitutive beta subunits 1–7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to the ... | PSMB5
Proteasome subunit beta type-5 as known as 20S proteasome subunit beta-5 is a protein that in humans is encoded by the PSMB5 gene.[1][2][3] This protein is one of the 17 essential subunits (alpha subunits 1–7, constitutive beta subunits 1–7, and inducible subunits including beta1i, beta2i, beta5i) that contribut... | https://www.wikidoc.org/index.php/PSMB5 | |
617116649825df1bb948729745dfddc47ac8fea9 | wikidoc | PSMB6 | PSMB6
Proteasome subunit beta type-6 also known as 20S proteasome subunit beta-1 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB6 gene.
This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, bet... | PSMB6
Proteasome subunit beta type-6 also known as 20S proteasome subunit beta-1 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB6 gene.[1][2][3]
This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including b... | https://www.wikidoc.org/index.php/PSMB6 | |
e732c9eed917b38f7c20339ef7acd3a38947ab77 | wikidoc | PSMB7 | PSMB7
Proteasome subunit beta type-7 as known as 20S proteasome subunit beta-2 is a protein that in humans is encoded by the PSMB7 gene.
This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to the ... | PSMB7
Proteasome subunit beta type-7 as known as 20S proteasome subunit beta-2 is a protein that in humans is encoded by the PSMB7 gene.[1][2]
This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contributes ... | https://www.wikidoc.org/index.php/PSMB7 | |
69580d864ae057c4b2054effa5811e565fca4fe6 | wikidoc | PSMB8 | PSMB8
Proteasome subunit beta type-8 as known as 20S proteasome subunit beta-5i is a protein that in humans is encoded by the PSMB8 gene.
This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to the... | PSMB8
Proteasome subunit beta type-8 as known as 20S proteasome subunit beta-5i is a protein that in humans is encoded by the PSMB8 gene.[1][2][3]
This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contribu... | https://www.wikidoc.org/index.php/PSMB8 | |
1b43c973ae2128db44d0dea6c02543d55349cf41 | wikidoc | PSMB9 | PSMB9
Proteasome subunit beta type-9 as known as 20S proteasome subunit beta-1i is a protein that in humans is encoded by the PSMB9 gene.
This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to the... | PSMB9
Proteasome subunit beta type-9 as known as 20S proteasome subunit beta-1i is a protein that in humans is encoded by the PSMB9 gene.[1][2][3]
This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contribu... | https://www.wikidoc.org/index.php/PSMB9 | |
16ffd81f95386702e237daaae88b4c64e75c1566 | wikidoc | PSMC1 | PSMC1
26S protease regulatory subunit 4, also known as 26S proteasome AAA-ATPase subunit Rpt2, is an enzyme that in humans is encoded by the PSMC1 gene. This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex. Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2 (this protein), Rpt... | PSMC1
26S protease regulatory subunit 4, also known as 26S proteasome AAA-ATPase subunit Rpt2, is an enzyme that in humans is encoded by the PSMC1 gene.[1][2] This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex.[3] Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2 (this pro... | https://www.wikidoc.org/index.php/PSMC1 | |
fa570febd9d78b6cc3338cef668671b821c861d0 | wikidoc | PSMC2 | PSMC2
26S protease regulatory subunit 7, also known as 26S proteasome AAA-ATPase subunit Rpt1, is an enzyme that in humans is encoded by the PSMC2 gene This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex. Six 26S proteasome AAA-ATPase subunits (Rpt1 (this protein), Rpt2, Rpt3... | PSMC2
26S protease regulatory subunit 7, also known as 26S proteasome AAA-ATPase subunit Rpt1, is an enzyme that in humans is encoded by the PSMC2 gene[1][2][3] This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex.[4] Six 26S proteasome AAA-ATPase subunits (Rpt1 (this protein... | https://www.wikidoc.org/index.php/PSMC2 | |
eedbc135627c5d5567e5d4e0d34e122394fd3980 | wikidoc | PSMC3 | PSMC3
26S protease regulatory subunit 6A, also known as 26S proteasome AAA-ATPase subunit Rpt5, is an enzyme that in humans is encoded by the PSMC3 gene. This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3, Rpt4, Rpt5 (... | PSMC3
26S protease regulatory subunit 6A, also known as 26S proteasome AAA-ATPase subunit Rpt5, is an enzyme that in humans is encoded by the PSMC3 gene.[1][2] This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex[3] Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3, Rp... | https://www.wikidoc.org/index.php/PSMC3 | |
dd37e0c0edc01551f8889c11cc5a2e0f60b6d712 | wikidoc | PSMC4 | PSMC4
26S protease regulatory subunit 6B, also known as 26S proteasome AAA-ATPase subunit Rpt3,is an enzyme that in humans is encoded by the PSMC4 gene. This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3 (this protein)... | PSMC4
26S protease regulatory subunit 6B, also known as 26S proteasome AAA-ATPase subunit Rpt3,is an enzyme that in humans is encoded by the PSMC4 gene.[1][2][3] This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex[4] Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3 (... | https://www.wikidoc.org/index.php/PSMC4 | |
ced626f5f4948147ff8782113c0872cfa49f50f2 | wikidoc | PSMC5 | PSMC5
26S protease regulatory subunit 8, also known as 26S proteasome AAA-ATPase subunit Rpt6, is an enzyme that in humans is encoded by the PSMC5 gene. This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3, Rpt4, Rpt5, a... | PSMC5
26S protease regulatory subunit 8, also known as 26S proteasome AAA-ATPase subunit Rpt6, is an enzyme that in humans is encoded by the PSMC5 gene.[1][2][3] This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex[4] Six 26S proteasome AAA-ATPase subunits (Rpt1, Rpt2, Rpt3, ... | https://www.wikidoc.org/index.php/PSMC5 |
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