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wikidoc
Thigh
Thigh In humans the thigh is the area between the pelvis and buttocks and the knee. Anatomically, it is part of the lower limb. The single bone in the thigh is called the femur. This bone is very thick and strong (due to the high proportion of cortical bone), and forms a ball and socket joint at the hip, and a condylar...
Thigh Template:Infobox Anatomy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] In humans the thigh is the area between the pelvis and buttocks and the knee. Anatomically, it is part of the lower limb. The single bone in the thigh is called the femur. This bone is very thick and strong (due to the high proportion of...
https://www.wikidoc.org/index.php/Thigh
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wikidoc
Thyme
Thyme Thyme (Thymus) (pronounced "time") is a genus of about 350 species of aromatic perennial herbaceous plants and sub-shrubs to 40 cm tall, in the family Lamiaceae and native to Europe, North Africa and Asia. A number of species have different chemotypes. The stems tend to be narrow or even wiry; the leaves are ever...
Thyme Thyme (Thymus) (pronounced "time") is a genus of about 350 species of aromatic perennial herbaceous plants and sub-shrubs to 40 cm tall, in the family Lamiaceae and native to Europe, North Africa and Asia. A number of species have different chemotypes. The stems tend to be narrow or even wiry; the leaves are eve...
https://www.wikidoc.org/index.php/Thyme
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wikidoc
Tinea
Tinea # Overview Dermatophytosis are a group of mycosis infections of the skin caused by parasitic fungi (dermatophytes). # Presentations Infections on the body may give rise to typical enlarging raised red rings of ringworm, infection on the skin of the feet may cause athlete's foot and in the groin jock itch. Invol...
Tinea Template:Seealso For patient information click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Dermatophytosis are a group of mycosis infections of the skin caused by parasitic fungi (dermatophytes). # Presentations Infections on the body may give rise to typical enlarging raised red rings o...
https://www.wikidoc.org/index.php/Tinea
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wikidoc
Titer
Titer # Overview A titer (or titre) is the unit in which the analytical detection of many substances is expressed. It is the result of a titration. Generally, the test is performed on an undiluted sample, and then repeated when the sample is mixed with 100% water, saline, or other diluent in repeated steps (a serial d...
Titer # Overview A titer (or titre) is the unit in which the analytical detection of many substances is expressed. It is the result of a titration. Generally, the test is performed on an undiluted sample, and then repeated when the sample is mixed with 100% water, saline, or other diluent in repeated steps (a serial d...
https://www.wikidoc.org/index.php/Titer
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wikidoc
Titin
Titin Titin /ˈtaɪtɪn/, also known as connectin, is a protein that, in humans, is encoded by the TTN gene. Titin is a giant protein, greater than 1 µm in length, that functions as a molecular spring which is responsible for the passive elasticity of muscle. It is composed of 244 individually folded protein domains conn...
Titin Titin /ˈtaɪtɪn/, also known as connectin, is a protein that, in humans, is encoded by the TTN gene.[1][2] Titin is a giant protein, greater than 1 µm in length,[3] that functions as a molecular spring which is responsible for the passive elasticity of muscle. It is composed of 244 individually folded protein do...
https://www.wikidoc.org/index.php/Titin
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wikidoc
Tooth
Tooth # Overview Teeth (singular, tooth) are structures found in the jaws of many vertebrates that are used to tear, scrape, and chew food. Some animals, particularly carnivores, also use teeth for hunting or defense. The roots of teeth are covered by gums. Teeth are among the most distinctive (and long-lasting) feat...
Tooth Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Template:Infobox Anatomy Teeth (singular, tooth) are structures found in the jaws of many vertebrates that are used to tear, scrape, and chew food. Some animals, particularly carnivores, also use teeth for hunting or defense. The roots of teeth are ...
https://www.wikidoc.org/index.php/Tooth
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Torso
Torso # Overview Torso is an anatomical term for the central part of the many animal bodies (including that of the human) from which extend the neck and limbs. It is sometimes referred to as the trunk. The torso includes the thorax and abdomen. # Anatomy ## Major organs Most critical organs are housed within the to...
Torso Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Torso is an anatomical term for the central part of the many animal bodies (including that of the human) from which extend the neck and limbs. It is sometimes referred to as the trunk. The torso includes the thorax and abdomen. # Anatomy ## Major ...
https://www.wikidoc.org/index.php/Torso
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Troya
Troya Troya is a brand of hand-made premium cigar owned by Lignum-2, Inc.. The brand was originally a Cuban brand, established in 1932, but the Cuban version is now offered only as an all-machine-made brand of only two vitolas. # History and Background This non-Cuban version of the Troya brand was introduced into the ...
Troya Troya is a brand of hand-made premium cigar owned by Lignum-2, Inc.. The brand was originally a Cuban brand, established in 1932, but the Cuban version is now offered only as an all-machine-made brand of only two vitolas.[1] # History and Background This non-Cuban version of the Troya brand was introduced into ...
https://www.wikidoc.org/index.php/Troya
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Tsuga
Tsuga Tsuga (from Template:Lang-ja, 栂; the name for Tsuga sieboldii ) is a genus of conifers in the family Pinaceae. The common name hemlock is derived from a perceived similarity in the smell of the crushed foliage to that of the unrelated herb poison hemlock; see hemlock for other senses of the word. Unlike the herb,...
Tsuga Tsuga (from Template:Lang-ja, 栂; the name for Tsuga sieboldii ) is a genus of conifers in the family Pinaceae. The common name hemlock is derived from a perceived similarity in the smell of the crushed foliage to that of the unrelated herb poison hemlock; see hemlock for other senses of the word. Unlike the herb...
https://www.wikidoc.org/index.php/Tsuga
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Virus
Virus A virus (from the Latin virus meaning "toxin" or "poison"), is a sub-microscopic infectious agent that is unable to grow or reproduce outside a host cell. Each viral particle, or virion, consists of genetic material, DNA or RNA, within a protective protein coat called a capsid. The capsid shape varies from simple...
Virus Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] A virus (from the Latin virus meaning "toxin" or "poison"), is a sub-microscopic infectious agent that is unable to grow or reproduce outside a host cell. Each viral particle, or virion, consists of genetic material, DNA or RNA, within a protective protein coat ...
https://www.wikidoc.org/index.php/Tumor_virus
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U2AF2
U2AF2 Splicing factor U2AF 65 kDa subunit is a protein that in humans is encoded by the U2AF2 gene. # Function U2 auxiliary factor (U2AF), composed of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit, which co...
U2AF2 Splicing factor U2AF 65 kDa subunit is a protein that in humans is encoded by the U2AF2 gene.[1] # Function U2 auxiliary factor (U2AF), composed of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit, whic...
https://www.wikidoc.org/index.php/U2AF2
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UBAP1
UBAP1 Ubiquitin-associated protein 1 is a protein that in humans is encoded by the UBAP1 gene. This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding ...
UBAP1 Ubiquitin-associated protein 1 is a protein that in humans is encoded by the UBAP1 gene.[1] This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin bind...
https://www.wikidoc.org/index.php/UBAP1
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wikidoc
UBE1C
UBE1C NEDD8-activating enzyme E1 catalytic subunit is a protein that in humans is encoded by the UBA3 gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-...
UBE1C NEDD8-activating enzyme E1 catalytic subunit is a protein that in humans is encoded by the UBA3 gene.[1][2] The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubi...
https://www.wikidoc.org/index.php/UBE1C
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UBE2I
UBE2I SUMO-conjugating enzyme UBC9 is an enzyme that in humans is encoded by the UBE2I gene. It is also sometimes referred to as "ubiquitin conjugating enzyme E2I" or "ubiquitin carrier protein 9", even though these names do not accurately describe its function. # Expression Four alternatively spliced transcript varia...
UBE2I SUMO-conjugating enzyme UBC9 is an enzyme that in humans is encoded by the UBE2I gene.[1] It is also sometimes referred to as "ubiquitin conjugating enzyme E2I" or "ubiquitin carrier protein 9", even though these names do not accurately describe its function. # Expression Four alternatively spliced transcript v...
https://www.wikidoc.org/index.php/UBE2I
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wikidoc
UBE2M
UBE2M NEDD8-conjugating enzyme Ubc12 is a protein that in humans is encoded by the UBE2M gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating en...
UBE2M NEDD8-conjugating enzyme Ubc12 is a protein that in humans is encoded by the UBE2M gene.[1][2] The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activa...
https://www.wikidoc.org/index.php/UBE2M
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wikidoc
UBE2Z
UBE2Z Ubiquitin conjugating enzyme E2 Z (UBE2Z), also known as UBA6-specific E2 enzyme 1 (USE1), is an enzyme that in humans is encoded by the UBE2Z gene on chromosome 17. It is ubiquitously expressed in many tissues and cell types. UBE2Z is an E2 ubiquitin conjugating enzyme and participates in the second step of prot...
UBE2Z Ubiquitin conjugating enzyme E2 Z (UBE2Z), also known as UBA6-specific E2 enzyme 1 (USE1), is an enzyme that in humans is encoded by the UBE2Z gene on chromosome 17.[1][2] It is ubiquitously expressed in many tissues and cell types.[3] UBE2Z is an E2 ubiquitin conjugating enzyme and participates in the second st...
https://www.wikidoc.org/index.php/UBE2Z
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wikidoc
UBE3A
UBE3A Ubiquitin-protein ligase E3A (UBE3A) also known as E6AP ubiquitin-protein ligase (E6AP) is an enzyme that in humans is encoded by the UBE3A gene. This enzyme is involved in targeting proteins for degradation within cells. Protein degradation is a normal process that removes damaged or unnecessary proteins and hel...
UBE3A Ubiquitin-protein ligase E3A (UBE3A) also known as E6AP ubiquitin-protein ligase (E6AP) is an enzyme that in humans is encoded by the UBE3A gene. This enzyme is involved in targeting proteins for degradation within cells. Protein degradation is a normal process that removes damaged or unnecessary proteins and he...
https://www.wikidoc.org/index.php/UBE3A
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wikidoc
UBXD5
UBXD5 UBX domain-containing protein 11 is a protein that in humans is encoded by the UBXN11 gene. # Function This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal regi...
UBXD5 UBX domain-containing protein 11 is a protein that in humans is encoded by the UBXN11 gene.[1][2] # Function This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-termin...
https://www.wikidoc.org/index.php/UBXD5
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wikidoc
UHMK1
UHMK1 U2AF homology motif (UHM) kinase 1, also known as UHMK1, is a protein which in humans is encoded by the UHMK1 gene. # Function UHMK1 is a kinase enzyme which phosphorylates the protein stathmin and has an RNA recognition motif of unknown function. # Clinical significance UHMK1 is highly expressed in the brain a...
UHMK1 U2AF homology motif (UHM) kinase 1, also known as UHMK1, is a protein which in humans is encoded by the UHMK1 gene.[1][2] # Function UHMK1 is a kinase enzyme which phosphorylates the protein stathmin and has an RNA recognition motif of unknown function.[3] # Clinical significance UHMK1 is highly expressed in t...
https://www.wikidoc.org/index.php/UHMK1
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wikidoc
UHRF1
UHRF1 Ubiquitin-like, containing PHD and RING finger domains, 1, also known as UHRF1, is a protein which in humans is encoded by the UHRF1 gene. # Function This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to hemi-methylated DNA during S-phase and recruits the main D...
UHRF1 Ubiquitin-like, containing PHD and RING finger domains, 1, also known as UHRF1, is a protein which in humans is encoded by the UHRF1 gene.[1][2] # Function This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to hemi-methylated DNA during S-phase and recruits the...
https://www.wikidoc.org/index.php/UHRF1
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wikidoc
UQCC2
UQCC2 Ubiquinol-cytochrome c reductase complex assembly factor 2 is a protein that in humans is encoded by the UQCC2 gene. Located in the mitochondrial nucleoid, this protein is a complex III assembly factor, playing a role in cytochrome b biogenesis along with the UQCC1 protein. It regulates insulin secretion and mito...
UQCC2 Ubiquinol-cytochrome c reductase complex assembly factor 2 is a protein that in humans is encoded by the UQCC2 gene. Located in the mitochondrial nucleoid, this protein is a complex III assembly factor, playing a role in cytochrome b biogenesis along with the UQCC1 protein.[1] It regulates insulin secretion and ...
https://www.wikidoc.org/index.php/UQCC2
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wikidoc
UQCC3
UQCC3 Ubiquinol-cytochrome c reductase complex assembly factor 3 is a protein that in humans is encoded by the UQCC3 gene. Located in mitochondria, this protein is involved in the assembly of mitochondrial Complex III, stabilizing supercomplexes containing Complex III. Mutations in the UQCC3 gene cause Complex III defi...
UQCC3 Ubiquinol-cytochrome c reductase complex assembly factor 3 is a protein that in humans is encoded by the UQCC3 gene.[1] Located in mitochondria, this protein is involved in the assembly of mitochondrial Complex III, stabilizing supercomplexes containing Complex III.[2] Mutations in the UQCC3 gene cause Complex I...
https://www.wikidoc.org/index.php/UQCC3
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wikidoc
UQCRB
UQCRB Ubiquinol-cytochrome c reductase binding protein, also known as UQCRB, Complex III subunit 7, QP-C, or Ubiquinol-cytochrome c reductase complex 14 kDa protein is a protein which in humans is encoded by the UQCRB gene.This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists ...
UQCRB Ubiquinol-cytochrome c reductase binding protein, also known as UQCRB, Complex III subunit 7, QP-C, or Ubiquinol-cytochrome c reductase complex 14 kDa protein is a protein which in humans is encoded by the UQCRB gene.This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists...
https://www.wikidoc.org/index.php/UQCRB
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wikidoc
UQCRQ
UQCRQ Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa is a protein that in humans is encoded by the UQCRQ gene. This ubiqinone-binding protein is a subunit of mitochondrial Complex III in the electron transport chain. A mutation in the UQCRQ gene has been shown to cause severe neurological disorders. ...
UQCRQ Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa is a protein that in humans is encoded by the UQCRQ gene. This ubiqinone-binding protein is a subunit of mitochondrial Complex III in the electron transport chain.[1] A mutation in the UQCRQ gene has been shown to cause severe neurological disorde...
https://www.wikidoc.org/index.php/UQCRQ
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USP11
USP11 Ubiquitin carboxyl-terminal hydrolase or Ubiquitin specific protease 11 is an enzyme that in humans is encoded by the USP11 gene. USP11 belongs to the Ubiquitin specific proteases family (USPs) which is a sub-family of the Deubiquitinating enzymes (DUBs).USPs are multiple domain proteases and belong to the C19 cy...
USP11 Ubiquitin carboxyl-terminal hydrolase or Ubiquitin specific protease 11 is an enzyme that in humans is encoded by the USP11 gene.[1][2] USP11 belongs to the Ubiquitin specific proteases family (USPs) which is a sub-family of the Deubiquitinating enzymes (DUBs).USPs are multiple domain proteases and belong to the...
https://www.wikidoc.org/index.php/USP11
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wikidoc
USP20
USP20 Ubiquitin carboxyl-terminal hydrolase 20 is an enzyme that in humans is encoded by the USP20 gene. Ubiquitin-specific protease 20 (USP20), also known as ubiquitin-binding protein 20 and VHL protein-interacting deubiquitinating enzyme 2 (VDU2), is a cysteine protease deubiquitinating enzyme (DUB). The catalytic si...
USP20 Ubiquitin carboxyl-terminal hydrolase 20 is an enzyme that in humans is encoded by the USP20 gene.[1][2] Ubiquitin-specific protease 20 (USP20), also known as ubiquitin-binding protein 20 and VHL protein-interacting deubiquitinating enzyme 2 (VDU2), is a cysteine protease deubiquitinating enzyme (DUB). The catal...
https://www.wikidoc.org/index.php/USP20
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wikidoc
USP48
USP48 Ubiquitin carboxyl-terminal hydrolase 48 is an enzyme that in humans is encoded by the USP48 gene. This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, ...
USP48 Ubiquitin carboxyl-terminal hydrolase 48 is an enzyme that in humans is encoded by the USP48 gene.[1][2] This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating en...
https://www.wikidoc.org/index.php/USP48
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USP53
USP53 Inactive ubiquitin carboxyl-terminal hydrolase 53 is a protein that in humans is encoded by the USP53 gene. Although USP53 is classified as a deubiquitinating enzyme based on sequence homology to other proteases from this group, it lacks a functionally essential histydine in the catalytic domaine and activity ass...
USP53 Inactive ubiquitin carboxyl-terminal hydrolase 53 is a protein that in humans is encoded by the USP53 gene.[1] Although USP53 is classified as a deubiquitinating enzyme based on sequence homology to other proteases from this group, it lacks a functionally essential histydine in the catalytic domaine and activity...
https://www.wikidoc.org/index.php/USP53
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wikidoc
USP9X
USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X is an enzyme that in humans is encoded by the USP9X gene. # Function This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactiva...
USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X is an enzyme that in humans is encoded by the USP9X gene.[1][2] # Function This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-i...
https://www.wikidoc.org/index.php/USP9X
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wikidoc
USP9Y
USP9Y Ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila), also known as USP9Y, is an enzyme which in humans is encoded by the USP9Y gene. It is required for sperm production. This enzyme is a member of the peptidase C19 family and is similar to ubiquitin-specific proteases, which cleave the ubiquiti...
USP9Y Ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila), also known as USP9Y, is an enzyme which in humans is encoded by the USP9Y gene.[1] It is required for sperm production. This enzyme is a member of the peptidase C19 family and is similar to ubiquitin-specific proteases, which cleave the ubiq...
https://www.wikidoc.org/index.php/USP9Y
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wikidoc
USPTO
USPTO # Overview The United States Patent and Trademark Office (PTO or USPTO) is an agency in the United States Department of Commerce that issues patents to inventors and businesses for their inventions, and trademark registration for product and intellectual property identification. The USPTO is currently based in A...
USPTO Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The United States Patent and Trademark Office (PTO or USPTO) is an agency in the United States Department of Commerce that issues patents to inventors and businesses for their inventions, and trademark registration for product and intellectual proper...
https://www.wikidoc.org/index.php/USPTO
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wikidoc
Ulcer
Ulcer Synonyms and keywords: ulceration An ulcer is a discontinuity or break in a bodily membrane that impedes the organ of which that membrane is a part from continuing its normal functions. Common forms of ulcers recognized in medicine include: - Ulcer (dermatology), a discontinuity of the skin or a break in the skin...
Ulcer Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Synonyms and keywords: ulceration An ulcer is a discontinuity or break in a bodily membrane that impedes the organ of which that membrane is a part from continuing its normal functions. Common forms of ulcers recognized in medicine include: - Ulcer (dermatology)...
https://www.wikidoc.org/index.php/Ulcer
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wikidoc
Umami
Umami Glutamate has a long history in cooking: it appears in Asian foods such as soy sauce and fish sauce, and in Italian food in parmesan cheese and anchovies. It is the taste of Marmite in the UK, of Golden Mountain sauce in Thailand, of Maggi Sauce worldwide, of Goya Sazón on the Latin islands of the Caribbean, of S...
Umami Template:Nihongo is a proposed addition to the currently accepted four basic tastes sensed by specialized receptor cells present on the human tongue.[1] The same taste is also known as xiānwèi (Template:Zh-ts) in Chinese cooking. Umami is a Japanese word meaning "savory" or "deliciousness" and so applies to the ...
https://www.wikidoc.org/index.php/Umami
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wikidoc
VAC14
VAC14 Protein VAC14 homolog, also known as ArPIKfyve (Associated Regulator of PIKfyve), is a protein that in humans is encoded by the VAC14 gene. # Functions and interactions The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events t...
VAC14 Protein VAC14 homolog, also known as ArPIKfyve (Associated Regulator of PIKfyve), is a protein that in humans is encoded by the VAC14 gene.[1][2][3] # Functions and interactions The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusio...
https://www.wikidoc.org/index.php/VAC14
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wikidoc
VAMP1
VAMP1 Vesicle-associated membrane protein 1 is a protein that in humans is encoded by the VAMP1 gene. # Function Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presyna...
VAMP1 Vesicle-associated membrane protein 1 is a protein that in humans is encoded by the VAMP1 gene.[1][2] # Function Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the ...
https://www.wikidoc.org/index.php/VAMP1
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wikidoc
VAMP2
VAMP2 Vesicle-associated membrane protein 2 is a protein that in humans is encoded by the VAMP2 gene. # Function Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presyna...
VAMP2 Vesicle-associated membrane protein 2 is a protein that in humans is encoded by the VAMP2 gene.[1][2] # Function Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the ...
https://www.wikidoc.org/index.php/VAMP2
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wikidoc
VAMP4
VAMP4 Vesicle-associated membrane protein 4 is a protein that in humans is encoded by the VAMP4 gene. # Function Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presyna...
VAMP4 Vesicle-associated membrane protein 4 is a protein that in humans is encoded by the VAMP4 gene.[1][2] # Function Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the ...
https://www.wikidoc.org/index.php/VAMP4
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wikidoc
VDAC2
VDAC2 Voltage-dependent anion-selective channel protein 2 is a protein that in humans is encoded by the VDAC2 gene on chromosome 10. This protein is a voltage-dependent anion channel and shares high structural homology with the other VDAC isoforms. VDACs are generally involved in the regulation of cell metabolism, mito...
VDAC2 Voltage-dependent anion-selective channel protein 2 is a protein that in humans is encoded by the VDAC2 gene on chromosome 10.[1][2] This protein is a voltage-dependent anion channel and shares high structural homology with the other VDAC isoforms.[3][4][5] VDACs are generally involved in the regulation of cell ...
https://www.wikidoc.org/index.php/VDAC2
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wikidoc
VDAC3
VDAC3 Voltage-dependent anion-selective channel protein 3 (VDAC3) is a protein that in humans is encoded by the VDAC3 gene on chromosome 8. The protein encoded by this gene is a voltage-dependent anion channel and shares high structural homology with the other VDAC isoforms. Nonetheless, VDAC3 demonstrates limited por...
VDAC3 Voltage-dependent anion-selective channel protein 3 (VDAC3) is a protein that in humans is encoded by the VDAC3 gene on chromosome 8. [1][2] The protein encoded by this gene is a voltage-dependent anion channel and shares high structural homology with the other VDAC isoforms.[1][2][3] Nonetheless, VDAC3 demonstr...
https://www.wikidoc.org/index.php/VDAC3
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wikidoc
VIPR1
VIPR1 Vasoactive intestinal polypeptide receptor 1 also known as VPAC1, is a protein, that in humans is encoded by the VIPR1 gene. VPAC1 is expressed in the brain (cerebral cortex, hippocampus, amygdala), lung, prostate, peripheral blood leukocytes, liver, small intestine, heart, spleen, placenta, kidney, thymus and te...
VIPR1 Vasoactive intestinal polypeptide receptor 1 also known as VPAC1, is a protein, that in humans is encoded by the VIPR1 gene.[1] VPAC1 is expressed in the brain (cerebral cortex, hippocampus, amygdala), lung, prostate, peripheral blood leukocytes, liver, small intestine, heart, spleen, placenta, kidney, thymus an...
https://www.wikidoc.org/index.php/VIPR1
1d4c68261e76ffa5c4cd01ae8c6a58067773cfd4
wikidoc
VIPR2
VIPR2 Vasoactive intestinal peptide receptor 2 also known as VPAC2, is a G-protein coupled receptor that in humans is encoded by the VIPR2 gene. # Tissue distribution VIPR2 is expressed in the uterus, prostate, smooth muscle of the gastrointestinal tract, seminal vesicles and skin, blood vessels and thymus. VIPR2 is a...
VIPR2 Vasoactive intestinal peptide receptor 2 also known as VPAC2, is a G-protein coupled receptor that in humans is encoded by the VIPR2 gene.[1] # Tissue distribution VIPR2 is expressed in the uterus, prostate, smooth muscle of the gastrointestinal tract, seminal vesicles and skin, blood vessels and thymus.[2][3] ...
https://www.wikidoc.org/index.php/VIPR2
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wikidoc
VLA-4
VLA-4 Integrin α4β1 (Very Late Antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the beta 1 subunit is 150 kDa. # Function The integrin VLA-4 is expressed on the cell surfaces of stem cells, progenitor cells, T and B cells, monocytes, natural kill...
VLA-4 Integrin α4β1 (Very Late Antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the beta 1 subunit is 150 kDa.[1] # Function The integrin VLA-4 is expressed on the cell surfaces of stem cells, progenitor cells, T and B cells, monocytes, natural ...
https://www.wikidoc.org/index.php/VLA-4
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wikidoc
VPS11
VPS11 Vacuolar protein sorting-associated protein 11 homolog is a protein that in humans is encoded by the VPS11 gene. # Function Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar p...
VPS11 Vacuolar protein sorting-associated protein 11 homolog is a protein that in humans is encoded by the VPS11 gene.[1] # Function Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuol...
https://www.wikidoc.org/index.php/VPS11
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wikidoc
VPS25
VPS25 Vacuolar protein-sorting-associated protein 25 is a protein that in humans is encoded by the VPS25 gene. It is a component of the endosome-associated complex ESCRT-II (Endosomal Sorting Complexes Required for Transport protein II). ESCRT (ESCRT-I, -II, -III) complexes orchestrate efficient sorting of ubiquitinate...
VPS25 Vacuolar protein-sorting-associated protein 25 is a protein that in humans is encoded by the VPS25 gene.[1][2] It is a component of the endosome-associated complex ESCRT-II (Endosomal Sorting Complexes Required for Transport protein II). ESCRT (ESCRT-I, -II, -III) complexes orchestrate efficient sorting of ubiqu...
https://www.wikidoc.org/index.php/VPS25
1cbe3e30725af22ddd9c89c9a110801f2c82bae1
wikidoc
VPS29
VPS29 VPS29 is a human gene coding for the vacuolar protein sorting protein Vps29, a component of the retromer complex. # Yeast homolog The homologous protein (one that performs the same function) in yeast is Vacuolar protein sorting 29 homolog (S. cerevisiae). # Function VPS29 belongs to a group of genes coding for ...
VPS29 VPS29 is a human gene coding for the vacuolar protein sorting protein Vps29, a component of the retromer complex.[1] # Yeast homolog The homologous protein (one that performs the same function) in yeast is Vacuolar protein sorting 29 homolog (S. cerevisiae).[2] # Function VPS29 belongs to a group of genes codi...
https://www.wikidoc.org/index.php/VPS29
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wikidoc
VPS35
VPS35 Vacuolar protein sorting-associated protein 35 is a protein that in humans is encoded by the VPS35 gene. This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins...
VPS35 Vacuolar protein sorting-associated protein 35 is a protein that in humans is encoded by the VPS35 gene.[1][2] This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of p...
https://www.wikidoc.org/index.php/VPS35
34acfed0e7fb38d80f7536029af19a1ab30a1c10
wikidoc
VPS53
VPS53 Vacuolar protein sorting 53 homolog (S. cerevisiae) is a protein that in humans is encoded by the VPS53 gene. # Function This gene encodes a protein with sequence similarity to the yeast Vps53p protein. Vps53p is involved in retrograde vesicle trafficking in late Golgi. . Mutations in VPS53 cause ...
VPS53 Vacuolar protein sorting 53 homolog (S. cerevisiae) is a protein that in humans is encoded by the VPS53 gene.[1] # Function This gene encodes a protein with sequence similarity to the yeast Vps53p protein. Vps53p is involved in retrograde vesicle trafficking in late Golgi. [provided by RefSeq, Jul 2008]. Mutati...
https://www.wikidoc.org/index.php/VPS53
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wikidoc
Vinca
Vinca Vinca (from Latin vincire "to bind, fetter") is a genus of five species in the family Apocynaceae, native to Europe, northwest Africa and southwest Asia. The common name, shared with the related genus Catharanthus, is Periwinkle. They are subshrubs or herbaceous, and have slender trailing stems 1-2 m (3-6 feet) ...
Vinca Vinca (from Latin vincire "to bind, fetter") is a genus of five species in the family Apocynaceae, native to Europe, northwest Africa and southwest Asia. The common name, shared with the related genus Catharanthus, is Periwinkle. They are subshrubs or herbaceous, and have slender trailing stems 1-2 m (3-6 feet)...
https://www.wikidoc.org/index.php/Vinca
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wikidoc
Vomer
Vomer The vomer (from Latin vomer, -ĕris, "ploughshare") is one of the unpaired facial bones of the skull. It is located in the midsagittal line, and touches the sphenoid, the ethmoid, the left and right palatine bones, and the left and right maxillary bones. # Vomeronasal organ The vomeronasal organ, also called Jac...
Vomer Template:Infobox Anatomy The vomer (from Latin vomer, -ĕris, "ploughshare") is one of the unpaired facial bones of the skull. It is located in the midsagittal line, and touches the sphenoid, the ethmoid, the left and right palatine bones, and the left and right maxillary bones. # Vomeronasal organ The vomerona...
https://www.wikidoc.org/index.php/Vomer
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wikidoc
WASF1
WASF1 Wiskott-Aldrich syndrome protein family member 1, also known as WASP-family verprolin homologous protein 1 (WAVE1), is a protein that in humans is encoded by the WASF1 gene. # Function The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP) family, plays a critical role downstre...
WASF1 Wiskott-Aldrich syndrome protein family member 1, also known as WASP-family verprolin homologous protein 1 (WAVE1), is a protein that in humans is encoded by the WASF1 gene.[1][2][3] # Function The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP) family, plays a critical rol...
https://www.wikidoc.org/index.php/WASF1
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wikidoc
WBP11
WBP11 # Alternative names - WW domain binding protein 11 (WBP11) - Npw38-binding protein (NpwBP) - Splicing factor that Interacts with PQBP-1 and PP1 (SIPP1) - SH3 domain binding Protein, 70 kDa (SNP70) # Function Studies suggest that Wbp11 plays a role in DNA/ RNA transcriptional or post-transcriptional events relat...
WBP11 # Alternative names - WW domain binding protein 11 (WBP11) - Npw38-binding protein (NpwBP) - Splicing factor that Interacts with PQBP-1 and PP1 (SIPP1) - SH3 domain binding Protein, 70 kDa (SNP70) # Function Studies suggest that Wbp11 plays a role in DNA/ RNA transcriptional or post-transcriptional events relat...
https://www.wikidoc.org/index.php/WBP11
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wikidoc
WDR12
WDR12 Ribosome biogenesis protein WDR12 is a protein that in humans is encoded by the WDR12 gene on chromosome 2. It is ubiquitously expressed in many tissues and cell types. WDR12 participates in ribosome biogenesis and cell proliferation as a component of the PeboW complex. This protein is associated with cardiovascu...
WDR12 Ribosome biogenesis protein WDR12 is a protein that in humans is encoded by the WDR12 gene on chromosome 2.[1][2][3] It is ubiquitously expressed in many tissues and cell types.[4] WDR12 participates in ribosome biogenesis and cell proliferation as a component of the PeboW complex.[1] This protein is associated ...
https://www.wikidoc.org/index.php/WDR12
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wikidoc
WDR45
WDR45 WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) is a protein that in humans is encoded by the WDR45 gene. Mutations in this gene cause a distinct form of Neurodegeneration with brain iron accumulation (NBIA). # Function WIPI-4 is a member of the WD repeat protein family. WD repeats are minimally...
WDR45 WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) is a protein that in humans is encoded by the WDR45 gene.[1][2] Mutations in this gene cause a distinct form of Neurodegeneration with brain iron accumulation (NBIA).[3] # Function WIPI-4 is a member of the WD repeat protein family. WD repeats are...
https://www.wikidoc.org/index.php/WDR45
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wikidoc
WDR47
WDR47 WD repeat domain 47 is a protein that in humans is encoded by the WDR47 gene. # Model organisms Model organisms have been used in the study of WDR47 function. A conditional knockout mouse line, called Wdr47tm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-thro...
WDR47 WD repeat domain 47 is a protein that in humans is encoded by the WDR47 gene.[1] # Model organisms Model organisms have been used in the study of WDR47 function. A conditional knockout mouse line, called Wdr47tm1a(EUCOMM)Wtsi[7][8] was generated as part of the International Knockout Mouse Consortium program — a...
https://www.wikidoc.org/index.php/WDR47
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wikidoc
WDR62
WDR62 WD repeat-containing protein 62 is a protein that in humans is encoded by the WDR62 gene. # Clinical relevance Mutations in the WDR62 gene cause of a wide spectrum of severe cerebral cortical malformations including microcephaly, pachygyria with cortical thickening, hypoplasia of the corpus callosum, polymicrogy...
WDR62 WD repeat-containing protein 62 is a protein that in humans is encoded by the WDR62 gene.[1][2] # Clinical relevance Mutations in the WDR62 gene cause of a wide spectrum of severe cerebral cortical malformations including microcephaly,[3] pachygyria with cortical thickening, hypoplasia of the corpus callosum[1]...
https://www.wikidoc.org/index.php/WDR62
685c7a8d2f2a8ae6812626a23ea5ff12b5e534b5
wikidoc
WFDC2
WFDC2 WAP four-disulfide core domain protein 2 - also known as Human Epididymis Protein 4 (HE4) - is a protein that in humans is encoded by the WFDC2 gene. HE4 is a tumor marker of ovarian cancer, with 80% sensitivity at a cut-off of 150 pmol/L. # Function This gene encodes a protein that is a member of the WFDC domai...
WFDC2 WAP four-disulfide core domain protein 2 - also known as Human Epididymis Protein 4[1] (HE4) - is a protein that in humans is encoded by the WFDC2 gene.[2][3][4] HE4 is a tumor marker of ovarian cancer, with 80% sensitivity at a cut-off of 150 pmol/L.[5] # Function This gene encodes a protein that is a member o...
https://www.wikidoc.org/index.php/WFDC2
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wikidoc
WIPF1
WIPF1 WAS/WASL-interacting protein family member 1 (WIP) is a protein that in humans is encoded by the WIPF1 gene. # Function This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. Overexpression of WIP in mammalian cells has been shown to increase actin polymerization....
WIPF1 WAS/WASL-interacting protein family member 1 (WIP) is a protein that in humans is encoded by the WIPF1 gene.[1][2] # Function This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. Overexpression of WIP in mammalian cells has been shown to increase actin polymeri...
https://www.wikidoc.org/index.php/WIPF1
ed55a9d50b901bbfcdf6faee6584f86696bd3c49
wikidoc
WIPI2
WIPI2 WD repeat domain phosphoinositide-interacting protein 2 is a protein that in humans is encoded by the WIPI2 gene. # Function WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous ...
WIPI2 WD repeat domain phosphoinositide-interacting protein 2 is a protein that in humans is encoded by the WIPI2 gene.[1][2] # Function WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simult...
https://www.wikidoc.org/index.php/WIPI2
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wikidoc
WNT16
WNT16 Protein Wnt-16 is a protein that in humans is encoded by the WNT16 gene. It has been proposed that stimulation of WNT16 expression in nearby normal cells is responsible for the development of chemotherapy-resistance in cancer cells. # Function The WNT gene family consists of structurally related genes that encod...
WNT16 Protein Wnt-16 is a protein that in humans is encoded by the WNT16 gene.[1][2] It has been proposed that stimulation of WNT16 expression in nearby normal cells is responsible for the development of chemotherapy-resistance in cancer cells.[3] # Function The WNT gene family consists of structurally related genes ...
https://www.wikidoc.org/index.php/WNT16
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wikidoc
WNT5A
WNT5A Protein Wnt-5a is a protein that in humans is encoded by the WNT5A gene. # Function The WNT gene family consists of structurally related genes that encode secreted signaling lipid modified glycoproteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulati...
WNT5A Protein Wnt-5a is a protein that in humans is encoded by the WNT5A gene.[1][2] # Function The WNT gene family consists of structurally related genes that encode secreted signaling lipid modified glycoproteins. These proteins have been implicated in oncogenesis and in several developmental processes, including r...
https://www.wikidoc.org/index.php/WNT5A
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wikidoc
WWTR1
WWTR1 WW domain-containing transcription regulator protein 1 is a protein that in humans is encoded by the WWTR1 gene. # Function WWTR1 It is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression b...
WWTR1 WW domain-containing transcription regulator protein 1 is a protein that in humans is encoded by the WWTR1 gene.[1][2][3] # Function WWTR1 It is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor sup...
https://www.wikidoc.org/index.php/WWTR1
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wikidoc
WebMD
WebMD WebMD is a medical and wellness information service, primarily known for its public internet site, which provides health information, a symptom checklist, pharmacy information, a place to store personal medical information, and an online community with over 140 moderated expert-led and peer-to-peer message boards...
WebMD WebMD is a medical and wellness information service, primarily known for its public internet site, which provides health information, a symptom checklist, pharmacy information, a place to store personal medical information, and an online community with over 140 moderated expert-led and peer-to-peer message board...
https://www.wikidoc.org/index.php/WebMD
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wikidoc
Wheat
Wheat Wheat (Triticum spp.) is a grass that is cultivated worldwide. Globally, it is an important human food grain ranking second in total production as a cereal crop behind maize; the third being rice. Wheat grain is a staple food used to make flour for leavened, flat and steamed breads; cookies, cakes, pasta, noodles...
Wheat Wheat (Triticum spp.)[1] is a grass that is cultivated worldwide. Globally, it is an important human food grain ranking second in total production as a cereal crop behind maize; the third being rice.[2] Wheat grain is a staple food used to make flour for leavened, flat and steamed breads; cookies, cakes, pasta, ...
https://www.wikidoc.org/index.php/Wheat
3e0056c2bcfca50126efb749273d5c8d9fcd8cf0
wikidoc
XB130
XB130 XB130 (also known as AFAP1L2) is a cytosolic adaptor protein and signal transduction mediator. XB130 regulates cell proliferation, cell survival, cell motility and gene expression. XB130 is highly similar to AFAP and is thus known as actin filament associated protein 1-like 2 (AFAP1L2). XB130 is a substrate and r...
XB130 XB130 (also known as AFAP1L2) is a cytosolic adaptor protein and signal transduction mediator. XB130 regulates cell proliferation, cell survival, cell motility and gene expression. XB130 is highly similar to AFAP and is thus known as actin filament associated protein 1-like 2 (AFAP1L2). XB130 is a substrate and ...
https://www.wikidoc.org/index.php/XB130
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wikidoc
XRCC1
XRCC1 DNA repair protein XRCC1 also known as X-ray repair cross-complementing protein 1 is a protein that in humans is encoded by the XRCC1 gene. XRCC1 is involved in DNA repair where it complexes with DNA ligase III. # Function XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure t...
XRCC1 DNA repair protein XRCC1 also known as X-ray repair cross-complementing protein 1 is a protein that in humans is encoded by the XRCC1 gene. XRCC1 is involved in DNA repair where it complexes with DNA ligase III. # Function XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure ...
https://www.wikidoc.org/index.php/XRCC1
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wikidoc
XRCC2
XRCC2 DNA repair protein XRCC2 is a protein that in humans is encoded by the XRCC2 gene. # Function This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double...
XRCC2 DNA repair protein XRCC2 is a protein that in humans is encoded by the XRCC2 gene.[1][2][3] # Function This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of ...
https://www.wikidoc.org/index.php/XRCC2
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wikidoc
XRCC3
XRCC3 DNA repair protein XRCC3 is a protein that in humans is encoded by the XRCC3 gene. # Function This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamste...
XRCC3 DNA repair protein XRCC3 is a protein that in humans is encoded by the XRCC3 gene.[1] # Function This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese ha...
https://www.wikidoc.org/index.php/XRCC3
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wikidoc
XYLT2
XYLT2 Xylosyltransferase 2 is an enzyme that in humans is encoded by the XYLT2 gene. # Function The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initi...
XYLT2 Xylosyltransferase 2 is an enzyme that in humans is encoded by the XYLT2 gene.[1][2] # Function The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein an...
https://www.wikidoc.org/index.php/XYLT2
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wikidoc
Xenin
Xenin Xenin is a peptide hormone produced by a subpopulation of chromogranin A-positive endocrine cells in the mucous membrane of the duodenum. The peptide has been found in humans, dogs, pigs, rats, and rabbits. In humans, xenin circulates in the blood plasma. There is a relationship between peaks of xenin concentrati...
Xenin Xenin is a peptide hormone produced by a subpopulation of chromogranin A-positive endocrine cells in the mucous membrane of the duodenum. The peptide has been found in humans, dogs, pigs, rats, and rabbits. In humans, xenin circulates in the blood plasma.[1] There is a relationship between peaks of xenin concent...
https://www.wikidoc.org/index.php/Xenin
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wikidoc
Xenon
Xenon # Overview Xenon (Template:PronEng in the UK, Template:IPA in the US) is a chemical element that has the symbol Xe and atomic number 54. A colorless, heavy, odorless noble gas, xenon occurs in the earth's atmosphere in trace amounts. Although generally unreactive, xenon can undergo a few chemical reactions such...
Xenon Template:Infobox xenon # Overview Xenon (Template:PronEng in the UK, Template:IPA in the US) is a chemical element that has the symbol Xe and atomic number 54. A colorless, heavy, odorless noble gas, xenon occurs in the earth's atmosphere in trace amounts.[1] Although generally unreactive, xenon can undergo a ...
https://www.wikidoc.org/index.php/Xenon
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wikidoc
YIPF1
YIPF1 Protein YIPF1 is a protein that in humans is encoded by the YIPF1 gene. # Model organisms Model organisms have been used in the study of YIPF1 function. A conditional knockout mouse line, called Yipf1tm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throughput...
YIPF1 Protein YIPF1 is a protein that in humans is encoded by the YIPF1 gene.[1][2] # Model organisms Model organisms have been used in the study of YIPF1 function. A conditional knockout mouse line, called Yipf1tm1a(EUCOMM)Wtsi[7][8] was generated as part of the International Knockout Mouse Consortium program — a hi...
https://www.wikidoc.org/index.php/YIPF1
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wikidoc
YPEL3
YPEL3 Yippee-like 3 (Drosophila) is a protein that in humans is encoded by the YPEL3 gene. YPEL3 has growth inhibitory effects in normal and tumor cell lines. One of five family members (YPEL1-5), YPEL3 was named in reference to its Drosophila melanogaster orthologue. Initially discovered in a gene expression profiling...
YPEL3 Yippee-like 3 (Drosophila) is a protein that in humans is encoded by the YPEL3 gene.[1][2] YPEL3 has growth inhibitory effects in normal and tumor cell lines.[3] One of five family members (YPEL1-5), YPEL3 was named in reference to its Drosophila melanogaster orthologue.[2] Initially discovered in a gene express...
https://www.wikidoc.org/index.php/YPEL3
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wikidoc
YWHAG
YWHAG 14-3-3 protein gamma is a protein that in humans is encoded by the YWHAG gene. This gene product belongs to the 14-3-3 protein family which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100...
YWHAG 14-3-3 protein gamma is a protein that in humans is encoded by the YWHAG gene.[1][2] This gene product belongs to the 14-3-3 protein family which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein...
https://www.wikidoc.org/index.php/YWHAG
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wikidoc
YWHAZ
YWHAZ 14-3-3 protein zeta/delta (14-3-3ζ) is a protein that in humans is encoded by the YWHAZ gene on chromosome 8. The protein encoded by this gene is a member of the 14-3-3 protein family and a central hub protein for many signal transduction pathways. 14-3-3ζ is a major regulator of apoptotic pathways critical to ce...
YWHAZ 14-3-3 protein zeta/delta (14-3-3ζ) is a protein that in humans is encoded by the YWHAZ gene on chromosome 8.[1][2] The protein encoded by this gene is a member of the 14-3-3 protein family and a central hub protein for many signal transduction pathways.[2][3] 14-3-3ζ is a major regulator of apoptotic pathways c...
https://www.wikidoc.org/index.php/YWHAZ
8a4d669555f657e405cf48a83f06f355048f5418
wikidoc
Yeast
Yeast Yeasts are a growth form of eukaryotic micro organisms classified in the kingdom Fungi, with about 1,500 species described; they dominate fungal diversity in the oceans. Most reproduce asexually by budding, although a few do by binary fission. Yeasts are unicellular, although some species with yeast forms may be...
Yeast Yeasts are a growth form of eukaryotic micro organisms classified in the kingdom Fungi, with about 1,500 species described;[1] they dominate fungal diversity in the oceans.[2] Most reproduce asexually by budding, although a few do by binary fission. Yeasts are unicellular, although some species with yeast forms...
https://www.wikidoc.org/index.php/Yeast
368e15f3f7dffb1fca49a1f87a990b4f08a350ce
wikidoc
Ypadu
Ypadu # Ypadú Ypadú or ypadu is an unrefined, unconcentrated powder made from coca leaves and the ash of various other plants. Like coca teas consumed in Peru to adapt to sickness induced by high elevation, it has a long ethnobotanical history and cultural associations. A report by Pien Metaal and others written for t...
Ypadu # Ypadú Ypadú or ypadu is an unrefined, unconcentrated powder made from coca leaves and the ash of various other plants. Like coca teas consumed in Peru to adapt to sickness induced by high elevation, it has a long ethnobotanical history and cultural associations. A report by Pien Metaal and others written for t...
https://www.wikidoc.org/index.php/Ypadu
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wikidoc
ZAP70
ZAP70 ZAP-70 (Zeta-chain-associated protein kinase 70) is a protein normally expressed near the surface membrane of T cells and natural killer cells. It is part of the T cell receptor, and plays a critical role in T-cell signaling. Its molecular weight is 70 kDa, and it is a member of the protein-tyrosine kinase family...
ZAP70 ZAP-70 (Zeta-chain-associated protein kinase 70) is a protein normally expressed near the surface membrane of T cells and natural killer cells. It is part of the T cell receptor, and plays a critical role in T-cell signaling. Its molecular weight is 70 kDa, and it is a member of the protein-tyrosine kinase famil...
https://www.wikidoc.org/index.php/ZAP70
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wikidoc
ZFP36
ZFP36 Tristetraprolin (TTP), also known as zinc finger protein 36 homolog (ZFP36), is a protein that in humans, mice and rats is encoded by the ZFP36 gene. It is a member of the TIS11 (TPA-induced sequence) family, along with butyrate response factors 1 and 2. TTP binds to AU-rich elements (AREs) in the 3'-untranslated...
ZFP36 Tristetraprolin (TTP), also known as zinc finger protein 36 homolog (ZFP36), is a protein that in humans, mice and rats is encoded by the ZFP36 gene.[1][2] It is a member of the TIS11 (TPA-induced sequence) family, along with butyrate response factors 1 and 2.[3] TTP binds to AU-rich elements (AREs) in the 3'-un...
https://www.wikidoc.org/index.php/ZFP36
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wikidoc
ZFP57
ZFP57 Zinc finger protein 57 homolog (ZFP57), also known as zinc finger protein 698 (ZNF698), is a protein that in humans is encoded by the ZFP57 gene. # Function The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcripti...
ZFP57 Zinc finger protein 57 homolog (ZFP57), also known as zinc finger protein 698 (ZNF698), is a protein that in humans is encoded by the ZFP57 gene.[1] # Function The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcr...
https://www.wikidoc.org/index.php/ZFP57
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wikidoc
ZFPM2
ZFPM2 Zinc finger protein ZFPM2, i.e. zinc finger protein, FOG family member 2, but also termed Friend of GATA2, Friend of GATA-2, FOG2, or FOG-2, is a protein that in humans is encoded by the ZFPM2 and in mice by the Zfpm2 gene. The zinc finger-containing protein encoded by this gene is a widely expressed member of th...
ZFPM2 Zinc finger protein ZFPM2, i.e. zinc finger protein, FOG family member 2, but also termed Friend of GATA2, Friend of GATA-2, FOG2, or FOG-2, is a protein that in humans is encoded by the ZFPM2 and in mice by the Zfpm2 gene.[1][2][3] The zinc finger-containing protein encoded by this gene is a widely expressed me...
https://www.wikidoc.org/index.php/ZFPM2
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wikidoc
ZGRF1
ZGRF1 ZGRF1 is a protein in humans that is encoded by the ZGRF1 gene that has uncharacterised function and a weight of 236.6 kDa. This gene shows relatively low expression in most human tissues, with increased expression in situations of chemical dependence. ZGRF1 is orthologous to nearly all kingdoms of Eukarya. Funct...
ZGRF1 ZGRF1 is a protein in humans that is encoded by the ZGRF1 gene that has uncharacterised function and a weight of 236.6 kDa.[1] This gene shows relatively low expression in most human tissues, with increased expression in situations of chemical dependence. ZGRF1 is orthologous to nearly all kingdoms of Eukarya. F...
https://www.wikidoc.org/index.php/ZGRF1
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wikidoc
Zocor
Zocor Synonyms / Brand Names:Cholestat, Coledis, Colemin, Corolin, Denan, Labistatin, Lipex, Lodales, Medipo, Nivelipol, Pantok, Rendapid, Simovil, Simvastatin, Simvastatina, Simvastatine, Simvastatinum, Sinvacor, Sivastin, Synvinolin, Vasotenal, Vytorin, Zocor, Zocord # Dosing and Administration The recommended usual...
Zocor Synonyms / Brand Names:Cholestat, Coledis, Colemin, Corolin, Denan, Labistatin, Lipex, Lodales, Medipo, Nivelipol, Pantok, Rendapid, Simovil, Simvastatin, Simvastatina, Simvastatine, Simvastatinum, Sinvacor, Sivastin, Synvinolin, Vasotenal, Vytorin, Zocor, Zocord Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1...
https://www.wikidoc.org/index.php/Zocor
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wikidoc
2C-B
2C-B 2C-B, or 4-bromo-2,5-dimethoxyphenethylamine (sometimes referred to as 4-Bromo-2,5-dimethoxybenzeneethanamine) is a psychedelic drug of the 2C family, an entactogen. It was first synthesized by Alexander Shulgin in 1974. In his book PIHKAL (Phenethylamines I Have Known and Loved), the dosage range is listed as 16...
2C-B Template:OrganicBox small 2C-B, or 4-bromo-2,5-dimethoxyphenethylamine (sometimes referred to as 4-Bromo-2,5-dimethoxybenzeneethanamine) is a psychedelic drug of the 2C family, an entactogen. It was first synthesized by Alexander Shulgin in 1974. In his book PIHKAL (Phenethylamines I Have Known and Loved), the d...
https://www.wikidoc.org/index.php/2C-B
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wikidoc
2C-C
2C-C 2C-C is a psychedelic drug of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. The full name of the chemical is 4-chloro-2,5-dimethoxyphenethylamine. In his book PIHKAL (Phenethylamines I Have Known and Loved), Shulgin lists the dosage range as 20 to 40 mg. 2C-C is u...
2C-C 2C-C is a psychedelic drug of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. The full name of the chemical is 4-chloro-2,5-dimethoxyphenethylamine. In his book PIHKAL (Phenethylamines I Have Known and Loved), Shulgin lists the dosage range as 20 to 40 mg. 2C-C is ...
https://www.wikidoc.org/index.php/2C-C
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wikidoc
2C-D
2C-D 2C-D is a psychedelic drug of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. The full name of the chemical is 2,5-dimethoxy-4-methyl-phenethylamine. In his book PiHKAL (Phenethylamines I Have Known and Loved), Shulgin lists the dosage range as being from 20 to 80 mg....
2C-D 2C-D is a psychedelic drug of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. The full name of the chemical is 2,5-dimethoxy-4-methyl-phenethylamine. In his book PiHKAL (Phenethylamines I Have Known and Loved), Shulgin lists the dosage range as being from 20 to 80 mg...
https://www.wikidoc.org/index.php/2C-D
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wikidoc
2C-E
2C-E 2C-E (2,5-dimethoxy-4-ethylphenethylamine) is a psychedelic drug and phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. It is commonly active in the 10-20 mg range, taken orally, and highly dose-sensitive. Insufflating (ie administering the chemical nas...
2C-E 2C-E (2,5-dimethoxy-4-ethylphenethylamine) is a psychedelic drug and phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. It is commonly active in the 10-20 mg range, taken orally, and highly dose-sensitive. Insufflating (ie administering the chemical na...
https://www.wikidoc.org/index.php/2C-E
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wikidoc
2C-G
2C-G 2C-G is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. It has structural and pharmacodynamic properties similar to 2C-D and Ganesha. Like many of the phenethylamines in PiHKAL, 2C-G and its homologues (see below) have only been taken b...
2C-G 2C-G is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. It has structural and pharmacodynamic properties similar to 2C-D and Ganesha. Like many of the phenethylamines in PiHKAL, 2C-G and its homologues (see below) have only been taken ...
https://www.wikidoc.org/index.php/2C-G
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wikidoc
2C-I
2C-I 2C-I is a psychedelic drug and phenethylamine of the 2C family. It was developed and popularized by Alexander Shulgin. Its full chemical name is 2,5-dimethoxy-4-iodophenethylamine. It was described in Shulgin’s book PiHKAL. The drug is used both recreationally and as an entheogen but no medical or industrial u...
2C-I Template:OrganicBox small 2C-I is a psychedelic drug and phenethylamine of the 2C family. It was developed and popularized by Alexander Shulgin. Its full chemical name is 2,5-dimethoxy-4-iodophenethylamine. It was described in Shulgin’s book PiHKAL. The drug is used both recreationally and as an entheogen but...
https://www.wikidoc.org/index.php/2C-I
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wikidoc
2C-N
2C-N 2C-N, or 2,5-Dimethoxy-4-nitrophenethylamine, is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. # Chemistry The full name of the chemical is 2-(2,5-dimethoxy-4-nitrophenyl)ethanamine. Salts of 2C-N have a bright yellow to orange color...
2C-N 2C-N, or 2,5-Dimethoxy-4-nitrophenethylamine, is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. # Chemistry The full name of the chemical is 2-(2,5-dimethoxy-4-nitrophenyl)ethanamine. Salts of 2C-N have a bright yellow to orange colo...
https://www.wikidoc.org/index.php/2C-N
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wikidoc
2C-O
2C-O 2C-O (or 2,4,5-trimethoxyphenethylamine) is a phenethylamine of the 2C family. It is also a positional isomer of mescaline and was first synthesized by Jansen in 1931. This chemical is also called 2,4,5-TMPEA. It has structurally similar to the drugs mescaline and 2C-D. # Chemistry 2C-O is in a class of compou...
2C-O 2C-O (or 2,4,5-trimethoxyphenethylamine) is a phenethylamine of the 2C family. It is also a positional isomer of mescaline and was first synthesized by Jansen in 1931. This chemical is also called 2,4,5-TMPEA. It has structurally similar to the drugs mescaline and 2C-D. # Chemistry 2C-O is in a class of compo...
https://www.wikidoc.org/index.php/2C-O
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wikidoc
2C-P
2C-P 2C-P is an entheogenic phenethylamine and 2C compound first synthesized by Alexander Shulgin. # Chemistry 2C-P is 2,5-dimethoxy-4-(n)-propylphenethylamine. The full name of the chemical is 2-(2,5-dimethoxy-4-propylphenyl)ethanamine. # Dosage In his book 'PiHKAL' (Phenethylamines I Have Known and Loved), Shulgin...
2C-P 2C-P is an entheogenic phenethylamine and 2C compound first synthesized by Alexander Shulgin. # Chemistry 2C-P is 2,5-dimethoxy-4-(n)-propylphenethylamine. The full name of the chemical is 2-(2,5-dimethoxy-4-propylphenyl)ethanamine. # Dosage In his book 'PiHKAL' (Phenethylamines I Have Known and Loved), Shulgi...
https://www.wikidoc.org/index.php/2C-P
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wikidoc
2C-T
2C-T 2C-T (or 4-methylthio-2,5-DMPEA) is a psychedelic and hallucinogenic drug of the 2C family. It is used by some as an entheogen. It has structural and pharmacodynamic properties similar to the drugs mescaline and 2C-T-2. It was first synthesized and studied through a collaboration between David E. Nichols and Ale...
2C-T 2C-T (or 4-methylthio-2,5-DMPEA) is a psychedelic and hallucinogenic drug of the 2C family. It is used by some as an entheogen. It has structural and pharmacodynamic properties similar to the drugs mescaline and 2C-T-2. It was first synthesized and studied through a collaboration between David E. Nichols and Al...
https://www.wikidoc.org/index.php/2C-T
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wikidoc
A1CF
A1CF APOBEC1 complementation factor is a protein that in humans is encoded by the A1CF gene. # Gene Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these varia...
A1CF APOBEC1 complementation factor is a protein that in humans is encoded by the A1CF gene.[1][2][3] # Gene Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of t...
https://www.wikidoc.org/index.php/A1CF
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wikidoc
AATK
AATK Serine/threonine-protein kinase LMTK1 (also known as Apoptosis-associated tyrosine kinase) is an enzyme that in humans is encoded by the (AATK) gene. # Structure and expression The gene was identified in 1998. It is located on chromosome 17 (17q25.3) and is expressed in the pancreas, kidney, brain and lungs. The ...
AATK Serine/threonine-protein kinase LMTK1 (also known as Apoptosis-associated tyrosine kinase) is an enzyme that in humans is encoded by the (AATK) gene.[1][2][3] # Structure and expression The gene was identified in 1998. It is located on chromosome 17 (17q25.3) and is expressed in the pancreas, kidney, brain and l...
https://www.wikidoc.org/index.php/AATK
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wikidoc
ABAT
ABAT 4-Aminobutyrate aminotransferase is a protein that in humans is encoded by the ABAT gene. This gene is located in chromosome 16 at position of 13.2. This gene has also different name, to give some are GABA, GABAT, 4-aminobutyrate transaminase, NPD009 and etc. This gene is mainly and abundant located in neuronal ti...
ABAT 4-Aminobutyrate aminotransferase is a protein that in humans is encoded by the ABAT gene.[1] This gene is located in chromosome 16 at position of 13.2.[2] This gene has also different name, to give some are GABA, GABAT, 4-aminobutyrate transaminase, NPD009 and etc.[2] This gene is mainly and abundant located in n...
https://www.wikidoc.org/index.php/ABAT
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wikidoc
ABI1
ABI1 Abl interactor 1 also known as Abelson interactor 1 (Abi-1) is a protein that in humans is encoded by the ABI1 gene. # Function Abl interactor 1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, the encoded protein may p...
ABI1 Abl interactor 1 also known as Abelson interactor 1 (Abi-1) is a protein that in humans is encoded by the ABI1 gene.[1][2] # Function Abl interactor 1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, the encoded protei...
https://www.wikidoc.org/index.php/ABI1
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wikidoc
ABL2
ABL2 Tyrosine-protein kinase ABL2 also known as Abelson-related gene (Arg) is an enzyme that in humans is encoded by the ABL2 gene. # Function ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amin...
ABL2 Tyrosine-protein kinase ABL2 also known as Abelson-related gene (Arg) is an enzyme that in humans is encoded by the ABL2 gene.[1][2] # Function ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and exten...
https://www.wikidoc.org/index.php/ABL2
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wikidoc
ABVD
ABVD # Overview ABVD is a chemotherapy regimen used in the first-line treatment of Hodgkin's lymphoma. It consists of concurrent treatment with the chemotherapy drugs adriamycin, bleomycin, vinblastine and dacarbazine. # Indications As of 2006, ABVD is widely used as the initial chemotherapy treatment for newly diagn...
ABVD # Overview ABVD is a chemotherapy regimen used in the first-line treatment of Hodgkin's lymphoma. It consists of concurrent treatment with the chemotherapy drugs adriamycin, bleomycin, vinblastine and dacarbazine. # Indications As of 2006, ABVD is widely used as the initial chemotherapy treatment for newly diagn...
https://www.wikidoc.org/index.php/ABVD
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wikidoc
ACHE
ACHE Acetylcholinesterase (Yt blood group), also known as AChE, is a human enzyme coded for by a gene. Acetylcholinesterase hydrolyzes the neurotransmitter acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, ...
ACHE Acetylcholinesterase (Yt blood group), also known as AChE, is a human enzyme coded for by a gene. Acetylcholinesterase hydrolyzes the neurotransmitter acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes,...
https://www.wikidoc.org/index.php/ACHE
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wikidoc
ACO2
ACO2 Aconitase 2, mitochondrial is a protein that in humans is encoded by the ACO2 gene. # Structure The secondary structure of ACO2 consists of numerous alternating alpha helices and beta sheets (SCOP classification: α/β alternating). The tertiary structure reveals that the active site is buried in the middle of the ...
ACO2 Aconitase 2, mitochondrial is a protein that in humans is encoded by the ACO2 gene.[1] # Structure The secondary structure of ACO2 consists of numerous alternating alpha helices and beta sheets (SCOP classification: α/β alternating). The tertiary structure reveals that the active site is buried in the middle of ...
https://www.wikidoc.org/index.php/ACO2