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wikidoc
CCNF
CCNF G2/mitotic-specific cyclin-F is a protein that in humans is encoded by the CCNF gene. # Function This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the ...
CCNF G2/mitotic-specific cyclin-F is a protein that in humans is encoded by the CCNF gene.[1][2] # Function This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs ...
https://www.wikidoc.org/index.php/CCNF
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wikidoc
CCR1
CCR1 C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene. CCR1 has also recently been designated CD191 (cluster of differentiation 191). # Function This gene encodes a member of the beta chemokine receptor family, which belongs to G protein-coupled receptors. The ligands of this recep...
CCR1 C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene.[1] CCR1 has also recently been designated CD191 (cluster of differentiation 191). # Function This gene encodes a member of the beta chemokine receptor family, which belongs to G protein-coupled receptors. The ligands of this r...
https://www.wikidoc.org/index.php/CCR1
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wikidoc
CCR2
CCR2 C-C chemokine receptor type 2 (CCR2 or CD192 (cluster of differentiation 192) is a protein that in humans is encoded by the CCR2 gene. CCR2 is a chemokine receptor. # Gene This CCR2 gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the g...
CCR2 C-C chemokine receptor type 2 (CCR2 or CD192 (cluster of differentiation 192) is a protein that in humans is encoded by the CCR2 gene.[1] CCR2 is a chemokine receptor. # Gene This CCR2 gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by t...
https://www.wikidoc.org/index.php/CCR2
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wikidoc
CCR4
CCR4 C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194 (cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines: - CCL2 (MCP-1) -...
CCR4 C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene.[1][2][3] CCR4 has also recently been designated CD194 (cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines: - CCL2...
https://www.wikidoc.org/index.php/CCR4
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wikidoc
CCR5
CCR5 C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines. In humans, the CCR5 gene that encodes the CCR5 protein is located on the short (p) arm at position 21 on chromosome 3. Certain ...
CCR5 C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines. In humans, the CCR5 gene that encodes the CCR5 protein is located on the short (p) arm at position 21 on chromosome 3. Certain...
https://www.wikidoc.org/index.php/CCR5
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wikidoc
CCR9
CCR9 C-C chemokine receptor type 9 is a protein that in humans is encoded by the CCR9 gene. CCR9 has also recently been designated CDw199 (cluster of differentiation w199). The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to ...
CCR9 C-C chemokine receptor type 9 is a protein that in humans is encoded by the CCR9 gene.[1][2] CCR9 has also recently been designated CDw199 (cluster of differentiation w199). The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein simi...
https://www.wikidoc.org/index.php/CCR9
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wikidoc
CD31
CD31 Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17. PECAM-1 plays a key role in removing aged neutrophils from the body. # Function PECAM-1 is found on the surface of platelets, ...
CD31 Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17.[1][2][3][4] PECAM-1 plays a key role in removing aged neutrophils from the body. # Function PECAM-1 is found on the surface o...
https://www.wikidoc.org/index.php/CD-31
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wikidoc
CD14
CD14 CD14 (cluster of differentiation 14) is a human gene. The protein encoded by this gene is a component of the innate immune system. CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol tail (mCD14), the other a soluble form (sCD14). Soluble CD14 either appears after shedding of m...
CD14 CD14 (cluster of differentiation 14) is a human gene.[1][2] The protein encoded by this gene is a component of the innate immune system. CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol tail (mCD14), the other a soluble form (sCD14). Soluble CD14 either appears after sheddi...
https://www.wikidoc.org/index.php/CD14
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wikidoc
CD16
CD16 CD16, also known as FcγRIII, is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which participate in signal transduction. The most ...
CD16 CD16, also known as FcγRIII, is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages.[1] CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which participate in signal transduction.[2] Th...
https://www.wikidoc.org/index.php/CD16
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wikidoc
CD18
CD18 Integrin beta-2 (CD18) is a protein that in humans is encoded by the ITGB2 gene. It is the beta subunit of four different structures: - LFA-1 (paired with CD11a) - Macrophage-1 antigen (paired with CD11b) - Integrin alphaXbeta2 (paired with CD11c) - Integrin alphaDbeta2 (paired with CD11d) # Function The ITGB2 pr...
CD18 Integrin beta-2 (CD18) is a protein that in humans is encoded by the ITGB2 gene. It is the beta subunit of four different structures: - LFA-1 (paired with CD11a) - Macrophage-1 antigen (paired with CD11b) - Integrin alphaXbeta2 (paired with CD11c) - Integrin alphaDbeta2 (paired with CD11d) # Function The ITGB2 p...
https://www.wikidoc.org/index.php/CD18
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wikidoc
CD19
CD19 B-lymphocyte antigen CD19, also known as CD19 molecule (Cluster of Differentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein that in humans is encoded by the gene CD19. In humans, CD19 is expressed in all B lineage cells, except for plasma cells, and i...
CD19 B-lymphocyte antigen CD19, also known as CD19 molecule (Cluster of Differentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein that in humans is encoded by the gene CD19.[1][2] In humans, CD19 is expressed in all B lineage cells, except for plasma cells...
https://www.wikidoc.org/index.php/CD19
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wikidoc
CD1D
CD1D CD1D is the human gene that encodes the protein CD1d, a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are non-classical MHC proteins, related to the class I MHC proteins, and are involved in the presentation of lipi...
CD1D CD1D is the human gene that encodes the protein CD1d,[1] a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are non-classical MHC proteins, related to the class I MHC proteins, and are involved in the presentation of ...
https://www.wikidoc.org/index.php/CD1D
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wikidoc
CD20
CD20 B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. In humans CD20 is encoded by the MS4A1 gene. This gene encodes a member of the membrane-s...
CD20 B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity.[1] In humans CD20 is encoded by the MS4A1 gene.[2][3] This gene encodes a member of the ...
https://www.wikidoc.org/index.php/CD20
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wikidoc
CD22
CD22 CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development...
CD22 CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins.[1] It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the develop...
https://www.wikidoc.org/index.php/CD22
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wikidoc
CD23
CD23 CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macropha...
CD23 CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macroph...
https://www.wikidoc.org/index.php/CD23
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wikidoc
CD27
CD27 CD27 is a member of the tumor necrosis factor receptor superfamily. It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule. # Function The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenan...
CD27 CD27 is a member of the tumor necrosis factor receptor superfamily. It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule. # Function The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintena...
https://www.wikidoc.org/index.php/CD27
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wikidoc
CD28
CD28 CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in...
CD28 CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 i...
https://www.wikidoc.org/index.php/CD28
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wikidoc
CD29
CD29 Integrin beta-1 also known as CD29 is a protein that in humans is encoded by the ITGB1 gene. CD29 is an integrin unit associated with very late antigen receptors. It is known to conjoin with alpha-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. In cardiac muscle and skeletal...
CD29 Integrin beta-1 also known as CD29 is a protein that in humans is encoded by the ITGB1 gene.[1] CD29 is an integrin unit associated with very late antigen receptors. It is known to conjoin with alpha-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. In cardiac muscle and skel...
https://www.wikidoc.org/index.php/CD29
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wikidoc
CD30
CD30 CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. # Function This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the acti...
CD30 CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. # Function This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the act...
https://www.wikidoc.org/index.php/CD30
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wikidoc
CD33
CD33 CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It binds sialic acids, therefore is a member of the SIGLEC family of l...
CD33 CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage.[1] It is usually considered myeloid-specific, but it can also be found on some lymphoid cells.[2] It binds sialic acids, therefore is a member of the SIGLEC fami...
https://www.wikidoc.org/index.php/CD33
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wikidoc
CD34
CD34 CD34 is a transmembrane phosphoglycoprotein protein encoded by the CD34 gene in humans, mice, rats and other species. CD34 derives its name from the cluster of differentiation protocol that identifies cell surface antigens. CD34 was first described on hematopoietic stem cells independently by Civin et al. and Tind...
CD34 CD34 is a transmembrane phosphoglycoprotein protein encoded by the CD34 gene in humans, mice, rats and other species.[1][2][3] CD34 derives its name from the cluster of differentiation protocol that identifies cell surface antigens. CD34 was first described on hematopoietic stem cells independently by Civin et al...
https://www.wikidoc.org/index.php/CD34
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wikidoc
CD36
CD36 CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb (GPIIIB), or IV (GPIV) is a protein that in humans is encoded by the CD36 gene. The CD36 antigen is an integral membrane protei...
CD36 CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb (GPIIIB), or IV (GPIV) is a protein that in humans is encoded by the CD36 gene. The CD36 antigen is an integral membrane prote...
https://www.wikidoc.org/index.php/CD36
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wikidoc
CD38
CD38 CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. In humans,...
CD38 CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase is a glycoprotein[1] found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling.[2] In ...
https://www.wikidoc.org/index.php/CD38
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wikidoc
CD44
CD44 The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded by the CD44 gene on Chromosome 11. CD44 has been referred to as HCAM (homing cell adhesion molecule), Pgp-1 (phagocytic glycoprotein-1), Hermes antigen, lymphocyte...
CD44 The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded by the CD44 gene on Chromosome 11.[1] CD44 has been referred to as HCAM (homing cell adhesion molecule), Pgp-1 (phagocytic glycoprotein-1), Hermes antigen, lympho...
https://www.wikidoc.org/index.php/CD44
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wikidoc
CD46
CD46 CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene. CD46 is an inhibitory complement receptor. # Gene This gene is found in a cluster on chromosome 1q32 with other genes encoding structural co...
CD46 CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene.[1] CD46 is an inhibitory complement receptor.[2] # Gene This gene is found in a cluster on chromosome 1q32 with other genes encoding struct...
https://www.wikidoc.org/index.php/CD46
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wikidoc
CD47
CD47 CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory p...
CD47 CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily[1] and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulato...
https://www.wikidoc.org/index.php/CD47
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wikidoc
CD48
CD48 CD48 antigen (Cluster of Differentiation 48) also known as B-lymphocyte activation marker (BLAST-1) or signaling lymphocytic activation molecule 2 (SLAMF2) is a protein that in humans is encoded by the CD48 gene. CD48 is a member of the CD2 subfamily of the immunoglobulin superfamily (IgSF) which includes SLAM (si...
CD48 CD48 antigen (Cluster of Differentiation 48) also known as B-lymphocyte activation marker (BLAST-1) or signaling lymphocytic activation molecule 2 (SLAMF2) is a protein that in humans is encoded by the CD48 gene.[1] CD48 is a member of the CD2 subfamily of the immunoglobulin superfamily (IgSF) which includes SLAM...
https://www.wikidoc.org/index.php/CD48
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wikidoc
CD52
CD52 CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene. CD52 is present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes were derived. It also is found on monocytes and dendritic cells. Further...
CD52 CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene. CD52 is present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes were derived. It also is found on monocytes[1] and dendritic cells.[2] ...
https://www.wikidoc.org/index.php/CD52
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wikidoc
CD58
CD58 CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. This adhesi...
CD58 CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages.[1][2] It binds to CD2 (LFA-2) [3][4] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells...
https://www.wikidoc.org/index.php/CD58
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wikidoc
CD59
CD59 CD59 glycoprotein, also known as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is a protein that in humans is encoded by the CD59 gene. It belongs to the LY6/uPAR/alpha-neurotoxin protein family. CD59 attaches to host cells via a glycophosphatidylinositol (GPI) anchor...
CD59 CD59 glycoprotein, also known as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is a protein that in humans is encoded by the CD59 gene.[1] It belongs to the LY6/uPAR/alpha-neurotoxin protein family.[2] CD59 attaches to host cells via a glycophosphatidylinositol (GPI)...
https://www.wikidoc.org/index.php/CD59
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wikidoc
CD61
CD61 Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation found on thrombocytes. # Structure and function The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a be...
CD61 Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene.[1] CD61 is a cluster of differentiation found on thrombocytes.[2] # Structure and function The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain a...
https://www.wikidoc.org/index.php/CD61
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wikidoc
CD63
CD63 CD63 antigen is a protein that in humans is encoded by the CD63 gene. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. # Function The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin famil...
CD63 CD63 antigen is a protein that in humans is encoded by the CD63 gene.[1] CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. # Function The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin f...
https://www.wikidoc.org/index.php/CD63
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wikidoc
CD68
CD68 CD68 (Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia). # Structure and function Human CD68 is a transmembrane glycoprotein, heavily glycos...
CD68 CD68 (Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia).[1] # Structure and function Human CD68 is a transmembrane glycoprotein, heavily gl...
https://www.wikidoc.org/index.php/CD68
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wikidoc
CD69
CD69 CD69 (Cluster of Differentiation 69) is a human transmembrane C-Type lectin protein encoded by the CD69 gene. It is an early activation marker that is expressed in hematopoietic stem cells, T cells, and many other cell types in the immune system. It is also implicated in T cell differentation as well as lymphocyte...
CD69 CD69 (Cluster of Differentiation 69) is a human transmembrane C-Type lectin protein encoded by the CD69 gene. It is an early activation marker that is expressed in hematopoietic stem cells, T cells, and many other cell types in the immune system.[1] It is also implicated in T cell differentation as well as lympho...
https://www.wikidoc.org/index.php/CD69
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wikidoc
CD70
CD70 CD70 (Cluster of Differentiation 70) is a ligand for CD27. # Clinical significance The CD70 protein is expressed on highly activated lymphocytes (like in T- and B-cell lymphomas). It is therefore suggested that anti-CD70 antibodies might be a possible treatment for CD70 positive lymphomas as normal lymphocytes ha...
CD70 CD70 (Cluster of Differentiation 70) is a ligand for CD27. # Clinical significance The CD70 protein is expressed on highly activated lymphocytes (like in T- and B-cell lymphomas). It is therefore suggested that anti-CD70 antibodies might be a possible treatment for CD70 positive lymphomas as normal lymphocytes h...
https://www.wikidoc.org/index.php/CD70
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wikidoc
CD74
CD74 HLA class II histocompatibility antigen gamma chain also known as HLA-DR antigens-associated invariant chain or CD74 (Cluster of Differentiation 74), is a protein that in humans is encoded by the CD74 gene. The invariant chain (Abbreviated Ii) is a polypeptide involved in the formation and transport of MHC class ...
CD74 HLA class II histocompatibility antigen gamma chain also known as HLA-DR antigens-associated invariant chain or CD74 (Cluster of Differentiation 74), is a protein that in humans is encoded by the CD74 gene.[1][2] The invariant chain (Abbreviated Ii) is a polypeptide involved in the formation and transport of MHC...
https://www.wikidoc.org/index.php/CD74
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wikidoc
CD81
CD81 CD81 molecule, also known as CD81 (Cluster of Differentiation 81), is a protein which in humans is encoded by the CD81 gene. It is also known as 26 kDa cell surface protein, TAPA-1 (Target of the Antiproliferative Antibody 1), and Tetraspanin-28 (Tspan-28). # Gene The gene is located on the Watson (plus) strand o...
CD81 CD81 molecule, also known as CD81 (Cluster of Differentiation 81), is a protein which in humans is encoded by the CD81 gene.[1][2] It is also known as 26 kDa cell surface protein, TAPA-1 (Target of the Antiproliferative Antibody 1), and Tetraspanin-28 (Tspan-28). # Gene The gene is located on the Watson (plus) s...
https://www.wikidoc.org/index.php/CD81
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wikidoc
CD90
CD90 Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1 can be used as a marker for a variety of stem cells and for th...
CD90 Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1 can be used as a marker for a variety of stem cells and for t...
https://www.wikidoc.org/index.php/CD90
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wikidoc
CD93
CD93 CD93 (Cluster of Differentiation 93) is a protein that in humans is encoded by the CD93 gene. CD93 is a C-type lectin transmembrane receptor which plays a role not only in cell–cell adhesion processes but also in host defense. # Family CD93 belongs to the Group XIV C-Type lectin family, a group containing three ...
CD93 CD93 (Cluster of Differentiation 93) is a protein that in humans is encoded by the CD93 gene.[1][2][3] CD93 is a C-type lectin transmembrane receptor which plays a role not only in cell–cell adhesion processes but also in host defense.[3] # Family CD93 belongs to the Group XIV C-Type lectin family, a group cont...
https://www.wikidoc.org/index.php/CD93
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wikidoc
CD97
CD97 Cluster of differentiation 97 is a protein also known as BL-Ac encoded by the ADGRE5 gene. CD97 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Aut...
CD97 Cluster of differentiation 97 is a protein also known as BL-Ac[F2] encoded by the ADGRE5 gene.[1][2][3][4] CD97 is a member of the adhesion GPCR family.[5][6] Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domai...
https://www.wikidoc.org/index.php/CD97
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wikidoc
CD98
CD98 CD98 is a glycoprotein that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter (LAT1). LAT1 is a heterodimeric membrane transport protein that preferentially transports branched-chain (valine, leucine, isoleucine) and aromatic (tryptophan, tyrosine) amino acids. LA...
CD98 CD98 is a glycoprotein[1][2] that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter (LAT1). LAT1 is a heterodimeric membrane transport protein that preferentially transports branched-chain (valine, leucine, isoleucine) and aromatic (tryptophan, tyrosine) amino aci...
https://www.wikidoc.org/index.php/CD98
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wikidoc
CD99
CD99 CD99 antigen (Cluster of differentiation 99), also known as MIC2 or single-chain type-1 glycoprotein, is a heavily O-glycosylated transmembrane protein that is encoded by the CD99 gene in humans. The protein has a mass of 32 kD. Unusually for a gene present on the X chromosome, the CD99 gene does not undergo X in...
CD99 CD99 antigen (Cluster of differentiation 99), also known as MIC2 or single-chain type-1 glycoprotein, is a heavily O-glycosylated transmembrane protein that is encoded by the CD99 gene in humans.[1][2][3] The protein has a mass of 32 kD. Unusually for a gene present on the X chromosome, the CD99 gene does not un...
https://www.wikidoc.org/index.php/CD99
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wikidoc
Cdk1
Cdk1 Cell division cycle 2, G1 to S and G2 to M, also known as Cdk1 (CDC2), is a human gene. The protein encoded by this gene is called p34cdk1 and is a cyclin-dependent kinase in the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as maturation pr...
Cdk1 Cell division cycle 2, G1 to S and G2 to M, also known as Cdk1 (CDC2), is a human gene. The protein encoded by this gene is called p34cdk1 and is a cyclin-dependent kinase in the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as maturation p...
https://www.wikidoc.org/index.php/CDC2_gene
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wikidoc
CDC6
CDC6 Cell division control protein 6 homolog is a protein that in humans is encoded by the CDC6 gene. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replicatio...
CDC6 Cell division control protein 6 homolog is a protein that in humans is encoded by the CDC6 gene.[1][2] The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA rep...
https://www.wikidoc.org/index.php/CDC6
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wikidoc
CDH2
CDH2 N-cadherin, also known as Cadherin-2 (CDH2) or neural cadherin (NCAD) is a protein that in humans is encoded by the CDH2 gene. CDH2 has also been designated as CD325 (cluster of differentiation 325). N-cadherin is a transmembrane protein expressed in multiple tissues and functions to mediate cell–cell adhesion. In...
CDH2 N-cadherin, also known as Cadherin-2 (CDH2) or neural cadherin (NCAD) is a protein that in humans is encoded by the CDH2 gene.[1][2] CDH2 has also been designated as CD325 (cluster of differentiation 325). N-cadherin is a transmembrane protein expressed in multiple tissues and functions to mediate cell–cell adhes...
https://www.wikidoc.org/index.php/CDH2
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wikidoc
CDK9
CDK9 CDK9 or cyclin-dependent kinase 9 is a cyclin-dependent kinase associated with P-TEFb. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell ...
CDK9 CDK9 or cyclin-dependent kinase 9 is a cyclin-dependent kinase associated with P-TEFb. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell...
https://www.wikidoc.org/index.php/CDK9
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wikidoc
CDON
CDON Cell adhesion molecule-related/down-regulated by oncogenes is a protein that in humans is encoded by the CDON gene. CDON and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III (FNIII) repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, fo...
CDON Cell adhesion molecule-related/down-regulated by oncogenes is a protein that in humans is encoded by the CDON gene.[1][2] CDON and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III (FNIII) repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during developm...
https://www.wikidoc.org/index.php/CDON
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wikidoc
CDS2
CDS2 Phosphatidate cytidylyltransferase 2 is an enzyme that in humans is encoded by the CDS2 gene. Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C a...
CDS2 Phosphatidate cytidylyltransferase 2 is an enzyme that in humans is encoded by the CDS2 gene.[1][2][3] Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein ...
https://www.wikidoc.org/index.php/CDS2
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wikidoc
CDX1
CDX1 Homeobox protein CDX-1 is a protein in humans that is encoded by the CDX1 gene. CDX1 is expressed in the developing endoderm and its expression persists in the intestine throughout adulthood. CDX1 protein expression varies along the intestine, with high expression in intestinal crypts and diminishing expression al...
CDX1 Homeobox protein CDX-1 is a protein in humans that is encoded by the CDX1 gene.[1][2] CDX1 is expressed in the developing endoderm and its expression persists in the intestine throughout adulthood.[3] CDX1 protein expression varies along the intestine, with high expression in intestinal crypts and diminishing exp...
https://www.wikidoc.org/index.php/CDX1
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wikidoc
CDX2
CDX2 Homeobox protein CDX-2 is a protein that in humans is encoded by the CDX2 gene. This gene is a member of the caudal-related homeobox transcription factor family that is expressed in the nuclei of intestinal epithelial cells. # Function Cdx2 is the gene that directs early embryogenesis in mice. It is required to f...
CDX2 Homeobox protein CDX-2 is a protein that in humans is encoded by the CDX2 gene. This gene is a member of the caudal-related homeobox transcription factor family that is expressed in the nuclei of intestinal epithelial cells.[1] # Function Cdx2 is the gene that directs early embryogenesis in mice. It is required ...
https://www.wikidoc.org/index.php/CDX2
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wikidoc
CHD1
CHD1 Chromodomain-helicase-DNA-binding protein 1 is an enzyme that in humans is encoded by the CHD1 gene. The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of...
CHD1 Chromodomain-helicase-DNA-binding protein 1 is an enzyme that in humans is encoded by the CHD1 gene.[1][2][3] The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modif...
https://www.wikidoc.org/index.php/CHD1
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wikidoc
CHD2
CHD2 Chromodomain-helicase-DNA-binding protein 2 is an enzyme that in humans is encoded by the CHD2 gene. # Function The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modi...
CHD2 Chromodomain-helicase-DNA-binding protein 2 is an enzyme that in humans is encoded by the CHD2 gene.[1][2] # Function The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly ...
https://www.wikidoc.org/index.php/CHD2
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wikidoc
CHD3
CHD3 Chromodomain-helicase-DNA-binding protein 3 is an enzyme that in humans is encoded by the CHD3 gene. # Function This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protei...
CHD3 Chromodomain-helicase-DNA-binding protein 3 is an enzyme that in humans is encoded by the CHD3 gene.[1][2][3] # Function This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. T...
https://www.wikidoc.org/index.php/CHD3
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wikidoc
CHD4
CHD4 Chromodomain-helicase-DNA-binding protein 4 is an enzyme that in humans is encoded by the CHD4 gene. # Function The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transc...
CHD4 Chromodomain-helicase-DNA-binding protein 4 is an enzyme that in humans is encoded by the CHD4 gene.[1][2][3] # Function The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigene...
https://www.wikidoc.org/index.php/CHD4
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wikidoc
CHD7
CHD7 Chromodomain-helicase-DNA-binding protein 7 also known as ATP-dependent helicase CHD7 is an enzyme that in humans is encoded by the CHD7 gene. CHD7 is an ATP-dependent chromatin remodeler homologous to the Drosophila trithorax-group protein Kismet. Mutations in CHD7 are associated with CHARGE syndrome. # Model or...
CHD7 Chromodomain-helicase-DNA-binding protein 7 also known as ATP-dependent helicase CHD7 is an enzyme that in humans is encoded by the CHD7 gene.[1][2] CHD7 is an ATP-dependent chromatin remodeler homologous to the Drosophila trithorax-group protein Kismet.[3] Mutations in CHD7 are associated with CHARGE syndrome.[4...
https://www.wikidoc.org/index.php/CHD7
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wikidoc
CHD8
CHD8 Chromodomain-helicase-DNA-binding protein 8 is an enzyme that in humans is encoded by the CHD8 gene. # Function The gene CHD8 encodes the protein chromodomain helicase DNA binding protein 8, which is a chromatin regulator enzyme that is essential during fetal development. CHD8 is an ATP dependent enzyme. The prot...
CHD8 Chromodomain-helicase-DNA-binding protein 8 is an enzyme that in humans is encoded by the CHD8 gene.[1][2] # Function The gene CHD8 encodes the protein chromodomain helicase DNA binding protein 8,[3] which is a chromatin regulator enzyme that is essential during fetal development.[4] CHD8 is an ATP dependent enz...
https://www.wikidoc.org/index.php/CHD8
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wikidoc
CHKA
CHKA Choline kinase alpha is an enzyme that in humans is encoded by the CHKA gene. The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes t...
CHKA Choline kinase alpha is an enzyme that in humans is encoded by the CHKA gene.[1][2][3] The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also c...
https://www.wikidoc.org/index.php/CHKA
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wikidoc
CHL1
CHL1 Neural cell adhesion molecule L1-like protein also known as close homolog of L1 (CHL1) is a protein that in humans is encoded by the CHL1 gene. CHL1 is a cell adhesion molecule closely related to the L1. In melanocytic cells CHL1 gene expression may be regulated by MITF, and can act as a helicase protein during th...
CHL1 Neural cell adhesion molecule L1-like protein also known as close homolog of L1 (CHL1) is a protein that in humans is encoded by the CHL1 gene.[2] CHL1 is a cell adhesion molecule closely related to the L1. In melanocytic cells CHL1 gene expression may be regulated by MITF,[3] and can act as a helicase protein du...
https://www.wikidoc.org/index.php/CHL1
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wikidoc
CHOP
CHOP CHOP is the acronym for a chemotherapy regimen used in the treatment of non-Hodgkin lymphoma. CHOP stands for Cytoxan, Hydroxydaunorubicin (Adriamycin), Oncovin (Vincristine), Prednisone/Prednisolone. # Uses and indications CHOP consists of: - Cyclophosphamide - Hydroxydaunorubicin (alternative name) - doxorubi...
CHOP Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] CHOP is the acronym for a chemotherapy regimen used in the treatment of non-Hodgkin lymphoma. CHOP stands for Cytoxan, Hydroxydaunorubicin (Adriamycin), Oncovin (Vincristine), Prednisone/Prednisolone. # Uses and indications CHOP consists of: - Cyclophosphamide ...
https://www.wikidoc.org/index.php/CHOP
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wikidoc
CHUK
CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha (IKK-α) also known as IKK1 or conserved helix-loop-helix ubiquitous kinase (CHUK) is a protein kinase that in humans is encoded by the CHUK gene. IKK-α is part of the IκB kinase complex that plays an important role in regulating the NF-κB transcription fact...
CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha (IKK-α) also known as IKK1 or conserved helix-loop-helix ubiquitous kinase (CHUK) is a protein kinase that in humans is encoded by the CHUK gene.[1] IKK-α is part of the IκB kinase complex that plays an important role in regulating the NF-κB transcription ...
https://www.wikidoc.org/index.php/CHUK
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wikidoc
CIB1
CIB1 Calcium and integrin-binding protein 1 is a protein that in humans is encoded by the CIB1 gene. The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protei...
CIB1 Calcium and integrin-binding protein 1 is a protein that in humans is encoded by the CIB1 gene.[1][2][3] The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-depend...
https://www.wikidoc.org/index.php/CIB1
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wikidoc
CISH
CISH Cytokine-inducible SH2-containing protein is a protein that in humans is encoded by the CISH gene. CISH orthologs have been identified in most mammals with sequenced genomes. CISH controls T cell receptor (TCR) signaling, and variations of CISH with certain SNPs are associated with susceptibility to bacteremia, t...
CISH Cytokine-inducible SH2-containing protein is a protein that in humans is encoded by the CISH gene.[1][2][3] CISH orthologs [4] have been identified in most mammals with sequenced genomes. CISH controls T cell receptor (TCR) signaling, and variations of CISH with certain SNPs are associated with susceptibility to ...
https://www.wikidoc.org/index.php/CISH
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wikidoc
CIZ1
CIZ1 Cip1-interacting zinc finger protein is a protein that in humans is encoded by the CIZ1 gene. # Function The protein encoded by this gene is a zinc finger DNA binding transcription factor that interacts with CIP1 (p21 / CDKN1A), part of a complex with cyclin E. The encoded protein may regulate the cellular locali...
CIZ1 Cip1-interacting zinc finger protein is a protein that in humans is encoded by the CIZ1 gene.[1][2] # Function The protein encoded by this gene is a zinc finger DNA binding transcription factor that interacts with CIP1 (p21 / CDKN1A), part of a complex with cyclin E. The encoded protein may regulate the cellular...
https://www.wikidoc.org/index.php/CIZ1
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wikidoc
CLN3
CLN3 Battenin is a protein that in humans is encoded by the CLN3 gene located on chromosome 16. Battenin is not clustered into any Pfam clan, but it is included in the TCDB suggesting that it is a transporter. In humans, it belongs to the atypical SLCs due to its structurally and phylogenetically similarity to other SL...
CLN3 Battenin is a protein that in humans is encoded by the CLN3 gene located on chromosome 16.[1][2] Battenin is not clustered into any Pfam clan, but it is included in the TCDB suggesting that it is a transporter.[3] In humans, it belongs to the atypical SLCs[3][4] due to its structurally and phylogenetically simila...
https://www.wikidoc.org/index.php/CLN3
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wikidoc
CLN8
CLN8 Protein CLN8 is a protein that in humans is encoded by the CLN8 gene. # Molecular biology This gene encodes a transmembrane protein that localizes to the endoplasmic reticulum (ER) and recycles between the ER and the Golgi apparatus via COPII- and COPI-coated vesicles. CLN8 protein functions as a cargo receptor f...
CLN8 Protein CLN8 is a protein that in humans is encoded by the CLN8 gene.[1][2] # Molecular biology This gene encodes a transmembrane protein that localizes to the endoplasmic reticulum (ER) and recycles between the ER and the Golgi apparatus via COPII- and COPI-coated vesicles.[3] CLN8 protein functions as a cargo ...
https://www.wikidoc.org/index.php/CLN8
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wikidoc
CLPB
CLPB Caseinolytic peptidase B protein homolog(CLPB), also known as mitochondrial AAA ATPase chaperonin, is an enzyme that in humans is encoded by the CLPB gene, which encodes an ATP-dependent protease and chaperone. CLPB is localized in mitochondria and widely expressed in human tissues. High expression in adult brain ...
CLPB Caseinolytic peptidase B protein homolog(CLPB), also known as mitochondrial AAA ATPase chaperonin, is an enzyme that in humans is encoded by the CLPB gene,[1][2][3] which encodes an ATP-dependent protease and chaperone. CLPB is localized in mitochondria and widely expressed in human tissues. High expression in ad...
https://www.wikidoc.org/index.php/CLPB
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wikidoc
CMAH
CMAH Putative cytidine monophosphate-N-acetylneuraminic acid hydroxylase-like protein is an enzyme that in humans is encoded by the CMAH gene. # Function Sialic acids are terminal components of the carbohydrate chains of glycoconjugates involved in ligand–receptor, cell–cell, and cell–pathogen interactions. The two mo...
CMAH Putative cytidine monophosphate-N-acetylneuraminic acid hydroxylase-like protein is an enzyme that in humans is encoded by the CMAH gene.[1][2][3] # Function Sialic acids are terminal components of the carbohydrate chains of glycoconjugates involved in ligand–receptor, cell–cell, and cell–pathogen interactions. ...
https://www.wikidoc.org/index.php/CMAH
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wikidoc
GJB1
GJB1 Lua error in Module:Redirect at line 65: could not parse redirect on page "CMTX". Gap junction beta-1 protein (GJB1), also known as connexin 32 (Cx32) is a transmembrane protein that in humans is encoded by the GJB1 gene. Gap junction beta-1 protein is a member of the gap junction connexin family of proteins that ...
GJB1 Lua error in Module:Redirect at line 65: could not parse redirect on page "CMTX". Gap junction beta-1 protein (GJB1), also known as connexin 32 (Cx32) is a transmembrane protein that in humans is encoded by the GJB1 gene.[1] Gap junction beta-1 protein is a member of the gap junction connexin family of proteins t...
https://www.wikidoc.org/index.php/CMTX
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wikidoc
COA3
COA3 Cytochrome c oxidase assembly factor 3, also known as Coiled-coil domain-containing protein 56, or Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa is a protein that in humans is encoded by the COA3 gene. This gene encodes a member of the cytochrome c oxidase ass...
COA3 Cytochrome c oxidase assembly factor 3, also known as Coiled-coil domain-containing protein 56, or Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa is a protein that in humans is encoded by the COA3 gene. This gene encodes a member of the cytochrome c oxidase as...
https://www.wikidoc.org/index.php/COA3
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wikidoc
COA5
COA5 Cytochrome c oxidase assembly factor 5 is a protein that in humans is encoded by the COA5 gene. This gene encodes an ortholog of yeast Pet191, which in yeast is a subunit of a large oligomeric complex associated with the mitochondrial inner membrane, and required for the assembly of the cytochrome c oxidase comple...
COA5 Cytochrome c oxidase assembly factor 5 is a protein that in humans is encoded by the COA5 gene. This gene encodes an ortholog of yeast Pet191, which in yeast is a subunit of a large oligomeric complex associated with the mitochondrial inner membrane, and required for the assembly of the cytochrome c oxidase compl...
https://www.wikidoc.org/index.php/COA5
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wikidoc
COA6
COA6 Cytochrome c oxidase assembly factor 6 is a protein that in humans is encoded by the COA6 gene. Mitochondrial respiratory chain Complex IV, or cytochrome c oxidase, is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the ma...
COA6 Cytochrome c oxidase assembly factor 6 is a protein that in humans is encoded by the COA6 gene.[1] Mitochondrial respiratory chain Complex IV, or cytochrome c oxidase, is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in th...
https://www.wikidoc.org/index.php/COA6
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wikidoc
COA7
COA7 Cytochrome c oxidase assembly factor 7 (putative) (COA7), also known as Beta-lactamase hap-like protein, Respiratory chain assembly factor 1 (RESA1), Sel1 repeat-containing protein 1 (SELRC1), or C1orf163 is a protein that in humans is encoded by the COA7 gene. The protein encoded by COA7 is an assembly factor imp...
COA7 Cytochrome c oxidase assembly factor 7 (putative) (COA7), also known as Beta-lactamase hap-like protein, Respiratory chain assembly factor 1 (RESA1), Sel1 repeat-containing protein 1 (SELRC1), or C1orf163 is a protein that in humans is encoded by the COA7 gene.[1][2][3] The protein encoded by COA7 is an assembly ...
https://www.wikidoc.org/index.php/COA7
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wikidoc
COG2
COG2 Conserved oligomeric Golgi complex subunit 2 is a protein that in humans is encoded by the COG2 gene. Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi tran...
COG2 Conserved oligomeric Golgi complex subunit 2 is a protein that in humans is encoded by the COG2 gene.[1][2] Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Gol...
https://www.wikidoc.org/index.php/COG2
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wikidoc
COG4
COG4 Conserved oligomeric Golgi complex subunit 4 is a protein that in humans is encoded by the COG4 gene. Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi tran...
COG4 Conserved oligomeric Golgi complex subunit 4 is a protein that in humans is encoded by the COG4 gene.[1][2] Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Gol...
https://www.wikidoc.org/index.php/COG4
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wikidoc
COQ6
COQ6 Coenzyme Q6 monooxygenase is a protein that in humans is encoded by the COQ6 gene. # Function The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mito...
COQ6 Coenzyme Q6 monooxygenase is a protein that in humans is encoded by the COQ6 gene.[1] # Function The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the ...
https://www.wikidoc.org/index.php/COQ6
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wikidoc
COQ7
COQ7 The clk-1 (clock-1) gene encodes an enzyme (demethoxyubiquinone monooxygenase) that is necessary for ubiquinone biosynthesis in the worm Caenorhabditis elegans and other eukaryotes. The mouse version of the gene is called mclk-1 and the human, fruit fly and yeast homolog COQ7 (coenzyme Q biosynthesis protein 7). C...
COQ7 The clk-1 (clock-1) gene encodes an enzyme (demethoxyubiquinone monooxygenase) that is necessary for ubiquinone biosynthesis in the worm Caenorhabditis elegans and other eukaryotes. The mouse version of the gene is called mclk-1 and the human, fruit fly and yeast homolog COQ7 (coenzyme Q biosynthesis protein 7).[...
https://www.wikidoc.org/index.php/COQ7
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wikidoc
COQ9
COQ9 Ubiquinone biosynthesis protein COQ9, mitochondrial, also known as coenzyme Q9 homolog (COQ9), is a protein that in humans is encoded by the COQ9 gene. # Function This locus represents a mitochondrial ubiquinone biosynthesis gene. The encoded protein is likely necessary for biosynthesis of coenzyme Q10, as mutati...
COQ9 Ubiquinone biosynthesis protein COQ9, mitochondrial, also known as coenzyme Q9 homolog (COQ9), is a protein that in humans is encoded by the COQ9 gene.[1] # Function This locus represents a mitochondrial ubiquinone biosynthesis gene. The encoded protein is likely necessary for biosynthesis of coenzyme Q10, as mu...
https://www.wikidoc.org/index.php/COQ9
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wikidoc
CPA3
CPA3 Carboxypeptidase A3 (mast cell carboxypeptidase A), also known as CPA3, is an enzyme which in humans is encoded by the CPA3 gene. The "CPA3" gene expression has only been detected in mast cells and mast-cell-like lines, and CPA3 is located in secretory granules. CPA3 is one of 8-9 members of the A/B subfamily that...
CPA3 Carboxypeptidase A3 (mast cell carboxypeptidase A), also known as CPA3, is an enzyme which in humans is encoded by the CPA3 gene.[1][2] The "CPA3" gene expression has only been detected in mast cells and mast-cell-like lines, and CPA3 is located in secretory granules. CPA3 is one of 8-9 members of the A/B subfami...
https://www.wikidoc.org/index.php/CPA3
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wikidoc
CPN1
CPN1 Carboxypeptidase N catalytic chain is an enzyme that in humans is encoded by the CPN1 gene. Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also...
CPN1 Carboxypeptidase N catalytic chain is an enzyme that in humans is encoded by the CPN1 gene.[1][2][3] Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, an...
https://www.wikidoc.org/index.php/CPN1
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wikidoc
CPVL
CPVL Probable serine carboxypeptidase CPVL is an enzyme that in humans is encoded by the CPVL gene. The "CPVL" gene is expressed mainly in monocytes and macrophages, and it is located in the endoplasmatic reticulum and in the endosomal/lysosomal compartment. The distribution of CPVL suggests that the enzyme may be invo...
CPVL Probable serine carboxypeptidase CPVL is an enzyme that in humans is encoded by the CPVL gene.[1][2] The "CPVL" gene is expressed mainly in monocytes and macrophages,[1] and it is located in the endoplasmatic reticulum and in the endosomal/lysosomal compartment. The distribution of CPVL suggests that the enzyme m...
https://www.wikidoc.org/index.php/CPVL
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wikidoc
CRKL
CRKL Crk-like protein is a protein that in humans is encoded by the CRKL gene. # Function v-CRK avian sarcoma virus CT10-homolog-like contains one SH2 domain and two SH3 domains. CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a su...
CRKL Crk-like protein is a protein that in humans is encoded by the CRKL gene.[1][2] # Function v-CRK avian sarcoma virus CT10-homolog-like contains one SH2 domain and two SH3 domains. CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It ...
https://www.wikidoc.org/index.php/CRKL
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wikidoc
CRYM
CRYM Mu-crystallin homolog also known as NADP-regulated thyroid-hormone-binding protein (THBP) is a protein that in humans is encoded by the CRYM gene. Multiple alternatively spliced transcript variants have been found for this gene. # Function Crystallins are separated into two classes: taxon-specific and ubiquitous....
CRYM Mu-crystallin homolog also known as NADP-regulated thyroid-hormone-binding protein (THBP) is a protein that in humans is encoded by the CRYM gene. Multiple alternatively spliced transcript variants have been found for this gene.[1][2] # Function Crystallins are separated into two classes: taxon-specific and ubiq...
https://www.wikidoc.org/index.php/CRYM
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wikidoc
CST1
CST1 Cystatin-SN is a protein that in humans is encoded by the CST1 gene. "The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three ...
CST1 Associate Editor(s)-in-Chief: Henry A. Hoff Cystatin-SN is a protein that in humans is encoded by the CST1 gene.[1] "The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never ac...
https://www.wikidoc.org/index.php/CST1
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wikidoc
CST2
CST2 Cystatin-SA is a protein that in humans is encoded by the CST2 gene. "The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three ...
CST2 Associate Editor(s)-in-Chief: Henry A. Hoff Cystatin-SA is a protein that in humans is encoded by the CST2 gene.[1] "The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never ac...
https://www.wikidoc.org/index.php/CST2
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wikidoc
CST4
CST4 Cystatin-S is a protein that in humans is encoded by the CST4 gene. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three in...
CST4 Associate Editor(s)-in-Chief: Henry A. Hoff Cystatin-S is a protein that in humans is encoded by the CST4 gene.[1][2] The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never a...
https://www.wikidoc.org/index.php/CST4
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wikidoc
CTCF
CTCF Transcriptional repressor CTCF also known as 11-zinc finger protein or CCCTC-binding factor is a transcription factor that in humans is encoded by the CTCF gene. CTCF is involved in many cellular processes, including transcriptional regulation, insulator activity, V(D)J recombination and regulation of chromatin a...
CTCF Transcriptional repressor CTCF also known as 11-zinc finger protein or CCCTC-binding factor is a transcription factor that in humans is encoded by the CTCF gene.[1][2] CTCF is involved in many cellular processes, including transcriptional regulation, insulator activity, V(D)J recombination[3] and regulation of c...
https://www.wikidoc.org/index.php/CTCF
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wikidoc
CTGF
CTGF CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferat...
CTGF CTGF, also known as CCN2 or connective tissue growth factor,[1][2] is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein).[3][4][5] CTGF has important roles in many biological processes, including cell adhesion, migra...
https://www.wikidoc.org/index.php/CTGF
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wikidoc
CUL1
CUL1 Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involv...
CUL1 Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins invol...
https://www.wikidoc.org/index.php/CUL1
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wikidoc
CUL3
CUL3 Cullin 3 is a protein that in humans is encoded by the CUL3 gene. Cullin 3 protein belongs to the family of cullins which in mammals contains eight proteins (Cullin 1, Cullin 2, Cullin 3, Cullin 4A, Cullin 4B, Cullin 5, Cullin 7 and Cullin 9). Cullin proteins are an evolutionarily conserved family of proteins thro...
CUL3 Cullin 3 is a protein that in humans is encoded by the CUL3 gene.[1][2][3] Cullin 3 protein belongs to the family of cullins which in mammals contains eight proteins (Cullin 1, Cullin 2, Cullin 3, Cullin 4A, Cullin 4B, Cullin 5, Cullin 7 and Cullin 9).[4] Cullin proteins are an evolutionarily conserved family of ...
https://www.wikidoc.org/index.php/CUL3
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wikidoc
CUL5
CUL5 Cullin-5 is a protein that in humans is encoded by the CUL5 gene. # Discovery The mammalian gene product was originally discovered by expression cloning, due to the protein's ability to mobilize intracellular calcium in response to the peptide hormone arginine vasopressin. It was first titled VACM-1, for vasopre...
CUL5 Cullin-5 is a protein that in humans is encoded by the CUL5 gene.[1][2][3] # Discovery The mammalian gene product was originally discovered by expression cloning, due to the protein's ability to mobilize intracellular calcium in response to the peptide hormone arginine vasopressin. It was first titled VACM-1, f...
https://www.wikidoc.org/index.php/CUL5
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wikidoc
CYBB
CYBB Cytochrome b-245 heavy chain also known as cytochrome b(558) subunit beta or NADPH oxidase 2 or Nox2 is a protein that in humans is encoded by the CYBB gene. The protein is a super-oxide generating enzyme which forms reactive oxygen species (ROS). # Function Nox2, or Cytochrome b (-245) is composed of cytochrome ...
CYBB Cytochrome b-245 heavy chain also known as cytochrome b(558) subunit beta or NADPH oxidase 2 or Nox2 is a protein that in humans is encoded by the CYBB gene.[1] The protein is a super-oxide generating enzyme which forms reactive oxygen species (ROS). # Function Nox2, or Cytochrome b (-245) is composed of cytochr...
https://www.wikidoc.org/index.php/CYBB
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wikidoc
CYC1
CYC1 Cytochrome c1, heme protein, mitochondrial (CYC1), also known as UQCR4, MC3DN6, Complex III subunit 4, Cytochrome b-c1 complex subunit 4, or Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit is a protein that in humans is encoded by the CYC1 gene. CYC1 is a respiratory subunit of Ubiquinol Cytochrome ...
CYC1 Cytochrome c1, heme protein, mitochondrial (CYC1), also known as UQCR4, MC3DN6, Complex III subunit 4, Cytochrome b-c1 complex subunit 4, or Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit is a protein that in humans is encoded by the CYC1 gene. CYC1 is a respiratory subunit of Ubiquinol Cytochrome...
https://www.wikidoc.org/index.php/CYC1
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wikidoc
EDTA
EDTA # Overview EDTA is a widely-used abbreviation for the chemical compound ethylenediaminetetraacetic acid (and many other names, see table). EDTA refers to the chelating agent with the formula (HO2CCH2)2NCH2CH2N(CH2CO2H)2. This amino acid is widely used to sequester di- and trivalent metal ions. EDTA binds to met...
EDTA Template:Chembox new Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview EDTA is a widely-used abbreviation for the chemical compound ethylenediaminetetraacetic acid (and many other names, see table). EDTA refers to the chelating agent with the formula (HO2CCH2)2NCH2CH2N(CH2CO2H)2. This amino acid is ...
https://www.wikidoc.org/index.php/Calcium_Disodium_Versenate
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wikidoc
Iron
Iron # Overview Iron is a chemical element with symbol Fe (from Template:Lang-la) and atomic number 26. It is a metal in the first transition series. It is by mass the most common element on Earth, forming much of Earth's outer and inner core. It is the fourth most common element in the Earth's crust. Its abundance in...
Iron Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Iron is a chemical element with symbol Fe (from Template:Lang-la) and atomic number 26. It is a metal in the first transition series.[1] It is by mass the most common element on Earth, forming much of Earth's outer and inner core. It is the fourth mos...
https://www.wikidoc.org/index.php/Carbonyl_iron
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wikidoc
Cash
Cash Cash usually refers to money in the form of liquid currency, such as banknotes or coins. Sometimes used as a street name or slang for Fentanyl. # Etymology The English word cash is of the French caisse, itself a borrowing of the Provençal caissa. That Provençal word is a derivative of the Latin capsa (box, chest...
Cash Cash usually refers to money in the form of liquid currency, such as banknotes or coins. Sometimes used as a street name or slang for Fentanyl. # Etymology The English word cash is of the French caisse, itself a borrowing of the Provençal caissa. That Provençal word is a derivative of the Latin capsa (box, ches...
https://www.wikidoc.org/index.php/Cash
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wikidoc
Scar
Scar # Overview Scars are areas of fibrous tissue that replace normal skin (or other tissue) after injury. A scar results from the biologic process of wound repair in the skin and other tissues of the body. Thus, scarring is a natural part of the healing process. With the exception of very minor lesions, every wound (...
Scar Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Scars are areas of fibrous tissue that replace normal skin (or other tissue) after injury. A scar results from the biologic process of wound repair in the skin and other tissues of the body. Thus, scarring is a natural part of the healing process. Wit...
https://www.wikidoc.org/index.php/Cicatricial
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wikidoc
Gene
Gene A gene is a locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions and/or other functional sequence regions. The physical development and phenotype of organisms can be thought of as a product of genes interacting with each othe...
Gene Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] A gene is a locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions and/or other functional sequence regions.[1][2] The physical development and phenotype of organisms can be t...
https://www.wikidoc.org/index.php/Cistron
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wikidoc
ClpX
ClpX ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial is an enzyme that in humans is encoded by the CLPX gene. This protein is a member of the family of AAA Proteins (AAA+ ATPase) and is to form the protein complex of Clp protease (Endopeptidase Clp). # Structure ## Protein Structure The knowle...
ClpX ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial is an enzyme that in humans is encoded by the CLPX gene. This protein is a member of the family of AAA Proteins (AAA+ ATPase) and is to form the protein complex of Clp protease (Endopeptidase Clp). # Structure ## Protein Structure The knowl...
https://www.wikidoc.org/index.php/ClpX
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wikidoc
Cmax
Cmax # Overview Cmax is a term used in pharmacokinetics refers to the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administrated and prior to the administration of a second dose. Cmax is the opposite of Cmin, which is the minimu...
Cmax Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2] # Overview Cmax is a term used in pharmacokinetics refers to the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been a...
https://www.wikidoc.org/index.php/Cmax
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wikidoc
Coca
Coca Coca is a plant in the family Erythroxylaceae, native to north-western South America. The plant plays a significant role in traditional Andean culture. It is used by Andean cultures such as the Quechuas of Peru as a messenger from the Gods, but is best-known in most of the world for the stimulant drug cocaine that...
Coca Coca is a plant in the family Erythroxylaceae, native to north-western South America. The plant plays a significant role in traditional Andean culture. It is used by Andean cultures such as the Quechuas of Peru as a messenger from the Gods, but is best-known in most of the world for the stimulant drug cocaine tha...
https://www.wikidoc.org/index.php/Coca